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A new study from the University of California, San Francisco suggests that cutting back on ultra-processed foods could help alleviate symptoms of depression. The research, recently published in JAMA Psychiatry and funded by the National Institutes of Health, found that participants who reduced their intake of ultra-processed foods saw significant improvements in their depression symptoms.
The study, led by Andrew Crystal, MD, involved 20 participants who transitioned from a regular ultra-processed diet to healthier foods. The participants experienced moderate to large improvements in three different measures of depression, as well as slight improvements in anxiety scores.
Ultra-processed foods, such as packaged snacks and fast foods, are known to contain ingredients like preservatives and artificial flavors that may negatively impact mental health. According to Nyasha Chagwedera, MD, PhD, reducing these foods can be challenging due to their addictive properties.
The study also highlighted the gut-brain connection, suggesting that ultra-processed foods can cause intestinal damage, leading to inflammation that may contribute to depression.
While the pilot study had a small sample size, researchers are planning a larger trial to further investigate the link between diet and depression. Enrollment for the second phase of the study is expected to begin in 2028.
Authors of the study include researchers from UCSF, the University of Queensland, Mayo Clinic, and Emory University. The study was funded by the National Institutes of Health and other organizations supporting translational research in mental health.
Source: www.sciencedaily.com
