As a healthcare professional, I often encounter concerns from patients about COVID-19, particularly those suffering from long-term effects. A common inquiry I receive is, “Can I get reinfected with COVID-19 while experiencing long-term symptoms from a previous infection?“
Many individuals believe that enduring the virus for an extended period grants them some level of immunity against future infections. Unfortunately, this assumption is not accurate.
Long-lasting COVID-19 symptoms, including fatigue, breathing difficulties, and cognitive issues, can persist for months after initial infection. Regrettably, even prolonged exposure to COVID-19 does not shield you from reinfection.
The protective effects from previous infections and vaccinations fade over time. New variants of the virus, such as Omicron KP.3 and XEC in 2025, can evade the immune response.
This means that even if you’re grappling with persistent COVID-19 symptoms, it’s possible to contract the virus again, which may exacerbate symptoms or prolong recovery.
A positive COVID-19 test may indicate a reinfection with the same variant or a new one, but either way, it remains a manifestation of the coronavirus. Vaccines, particularly the 2025 booster shot, can significantly reduce the risk of severe illness. If you’re experiencing long-term COVID-19 and test positive, ensure you rest, stay hydrated, and consult your physician if symptoms worsen.
The coronavirus is still prevalent and continues to mutate, necessitating the practice of protective measures. It’s essential to get tested if you feel unwell, wear masks in crowded indoor settings, and keep up with vaccinations.
These proactive steps help mitigate exposure and safeguard those around you, especially as we navigate the lingering effects of this virus.
This article addresses the question from Yorkshire’s Terence Caldwell: “Can I be infected with COVID-19 along with the new variants?“
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Source: www.sciencefocus.com












