A naturally occurring compound known as flavan-3-ol, present in cocoa, tea, apples, and grapes, has been shown to enhance blood pressure and vascular health, according to a recent meta-analysis conducted by researchers at the University of Surrey involving 145 prior studies.
Flavan-3-OL-rich foods and supplements, similar to medications, are regularly consumed, particularly by those with high blood pressure, to help lower blood pressure. Image credit: Lagou et al., doi: 10.1093/eurjpc/zwaf173.
“Flavan-3-ol found in cocoa, tea, and various fruits shows potential in enhancing blood pressure and vascular function, but is not yet utilized for cardiovascular prevention,” stated Professor Christian Heiss, the lead author of the study from the University of Surrey.
“Our meta-analysis evaluated how flavan-3-ol-rich interventions impact blood pressure and endothelial function.”
In the meta-analysis, the researchers examined data from 145 randomized controlled trials published between 1946 and 2024.
The findings indicated that regular intake of flavan-3-OLs could lead to reductions in blood pressure readings, particularly among individuals with elevated blood pressure or hypertension.
Some results showed that the average decrease in blood pressure was comparable to that produced by certain medications.
Additionally, flavan-3-ol was found to enhance endothelial function (the inner layer of blood vessels), which is crucial for overall cardiovascular health.
This improvement occurs independently of blood pressure changes, suggesting a broad positive impact on circulatory health.
“These results are promising for those seeking a simple way to manage blood pressure and support heart health through enjoyable dietary adjustments,” Professor Heiss added.
“Incorporating small amounts of commonly enjoyed foods such as tea, apples, dark chocolate, and cocoa powder into a balanced daily diet can provide beneficial flavan-3-ol levels.”
“While it should not replace prescribed medications or medical guidance, it can be a beneficial addition to a healthy lifestyle, particularly for individuals with high blood pressure, by incorporating flavan-3-ol-rich foods into their daily routine.”
“These encouraging findings warrant further research.”
A paper discussing the survey results has been published in the European Journal of Preventive Psychology.
____
Vasiriki Ragou et al. Effect of flavan-3-OL on blood pressure and endothelial function in various populations: a systematic review and meta-analysis of randomized controlled trials. European Journal of Preventive Psychology Published online on March 24th, 2025. doi: 10.1093/eurjpc/zwaf173
Source: www.sci.news
