The ketogenic diet causes damaged cells to accumulate in the organs of mice. These accumulations suggest that the keto diet may accelerate organ aging and increase the risk of diseases such as heart disease and cancer.
Many people adopt low-carbohydrate diets, such as ketogenic diets, to lose weight and control blood sugar levels, but research on their health effects is mixed, with some studies linking them to an increased risk of heart attack. It has been revealed.
You can learn more about david gius Researchers at the University of Texas Health Science Center in San Antonio fed six mice a ketogenic diet for three weeks. More than 90 percent of their calories come from fat and less than 1 percent from carbohydrates. The control group ate a standard diet with 17 percent of calories coming from fat and 58 percent from carbohydrates.
The researchers then analyzed tissue samples from the mice's hearts, kidneys, livers, and brains, looking for senescent cells. Aging occurs when cells become too damaged to function, but instead of dying, cells become zombie-like. These cells remain in the tissue and spew out toxins that cause inflammation.
Animals fed a ketogenic diet had significantly more senescent cells in their organs compared to animals fed a standard diet. For example, their kidneys contained, on average, four times as many markers of cellular senescence compared to the kidneys of animals fed a normal diet.
Senescent cells increase with age. Therefore, these findings suggest that the keto diet may accelerate organ aging and increase the risk of diseases such as heart disease, cancer, and type 2 diabetes. However, returning the mice to a standard diet reduced the number of senescent cells.
“The ketogenic diet is probably a good thing, but [it is not for] everyone. And importantly, you need to take a break,” Gius says. “I think our paper really says that we need to study this more rigorously.”
It is unclear how the results of these experiments will be reflected in people, he said. Russell Jones At the Van Andel Institute in Michigan. “They run a 90 percent fat diet, which is virtually impossible for us to adhere to as humans,” he says.
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Source: www.newscientist.com