Monitoring waste at only 20 airports can help identify potential pandemics

A global early warning system for disease outbreaks and future pandemics is possible with minimal surveillance. We test wastewater from just a few of our international flights at just 20 airports around the world.

If passengers fly while infected with bacteria or viruses, traces of these pathogens can be left in the waste, allowing airports to gather from the plane after the flight. “If you go to the airplane toilet, blow your nose and place it in the toilet, some of the genetic material from the pathogen can go. In the wastewater.” Guillaume St-Onge at Northeastern University, Massachusetts.

St-Onge and his colleagues used an A Simulator Called the Global Epidemic and Mobility Model, it analyzes how airport waste monitoring networks can detect new variants of the virus, such as those that cause Covid-19. By testing the model using different numbers and locations at airports, they have been able to provide 20 strategically located “sentinel airports” around the world and are as quickly as a network involving thousands of airports. It has been shown that occurrence can be detected efficiently. The larger network was only 20% faster, but cost more.

To detect new threats from anywhere in the world, your network should include major international airports in cities such as London, Paris, Dubai and Singapore. However, the team also showed how networks containing different airport sets could provide a more targeted detection of disease outbreaks that are likely to occur on a particular continent.

“This modeling study is the first to provide the actual number of sentinel airports needed to support effective global monitoring while optimizing resource use,” he says. jiaying li At the University of Sydney, Australia.

Additionally, airport-based networks provide useful information on disease outbreaks during an epidemic, such as how quickly diseases spread from person to person, and estimating people who may become infected from exposure to a single case. You can also do it, says ST-. Onge.

Such wastewater surveillance provides early warnings for known diseases and could also track new and emerging threats if genome data for bacterial or viral is available. “I don’t think I can look at the wastewater and say, ‘There’s a new pathogen out there.'” Temi Ibitoye At Brown University in Rhode Island. “But when new pathogens are announced, we can look at previous waste data very quickly and say, “Is this present in the sample?” “

There are still some nuances, such as the frequency of ingesting wastewater samples to track different pathogens. Other challenges include knowing the most efficient way to sample wastewater from an aircraft and assessing the actual effectiveness of the system, says Li.

Long-term surveillance programs also require cooperation from airlines and airports, along with consistent funding sources.

Individual airports can hesitate to participate as risks are recognized for business if infectious disease statistics become widely available. Unless a data processing agreement can alleviate such concerns, Trevor Charles At the University of Waterloo, Canada. He emphasized the importance of coordinated international funding to offset “local political considerations.”

However, given President Donald Trump’s launch of the US withdrawal from the organization, even coordination through international organizations such as the World Health Organization is bringing its own political complications, according to Ibitoye He said. Still, such research is “contributed to making it.” [the monitoring network] She says.