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You are at:Home » The overlooked nutrient that can play a vital role in preserving brain health as you age
The overlooked nutrient that can play a vital role in
Science April 20, 2025

The overlooked nutrient that can play a vital role in preserving brain health as you age

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Vitamin K is a crucial nutrient primarily found in green vegetables and may play a vital role in safeguarding the brain from cognitive decline.

Recent research suggests that vitamins, particularly vitamin K, could help in preserving the cells of the hippocampus, which is the brain’s memory center.

In a recent study, scientists conducted an experiment where 60 middle-aged mice were fed either low or regular diets supplemented with vitamin K for six months. Subsequent behavioral tests revealed the impact of vitamin K on mouse learning and memory.

The study showed that mice lacking vitamin K struggled with memory and learning tasks. Compared to mice on a regular diet, those deficient in vitamin K had difficulty recognizing familiar objects, indicating memory loss. They also faced challenges in spatial learning tasks, as evidenced by their performance in a water maze.

Green vegetables like spinach, kale, lettuce, Brussels sprouts, broccoli, and cabbage are excellent sources of vitamin K. Avocados and kiwi fruits also contain high levels of this nutrient – Credit: Mediterranean via Getty

Further analysis of the mice’s brain tissue revealed reduced neurogenesis in the hippocampus of vitamin K-deficient mice. Neurogenesis, the process of generating new neurons, is essential for maintaining brain health and protecting against damage.

“Neurogenesis is believed to be crucial for learning and memory functions, and its impairment may contribute to cognitive decline,” stated Ton Zheng, a research scientist at Tufts’ Center for Human Nutrition (HNRCA).

In addition to reduced neurogenesis, the brains of vitamin K-deficient mice also showed signs of inflammation, further linking vitamin K deficiency to cognitive decline.

While the study highlights the importance of vitamin K, researchers emphasize the significance of obtaining nutrients from a balanced diet rather than relying on supplements.

“It’s essential for people to consume a healthy diet rich in vegetables,” advised Professor Sarah Booth, senior author of the study and director of the HNRCA.

Most individuals typically obtain sufficient vitamin K from their diet, with sources like spinach, kale, peas, Brussels sprouts, broccoli, cabbage, parsley, avocados, and kiwi. However, older adults are more prone to vitamin K deficiency.

The study was recently published in the Journal of Nutrition.

Read more:

Source: www.sciencefocus.com

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