The reasons behind diet failures, as explained by a weight loss surgeon, and the key to successful eating.

Perhaps many of us have attempted to reduce our waistline by watching our calorie intake or hitting the gym, only to find little success. Should we be doing things differently?

According to Dr. Andrew Jenkinson, a consultant bariatric surgeon at University College London Hospital and the author of “Why do we eat (overeating)?” and “How to eat (and still lose weight)”, losing weight has more to do with eating foods that manage levels of leptin hormone rather than focusing on calorie counting or exercise.

So what exactly is leptin, and how does it work? Dr. Jenkinson shared insights in a recent discussion with us about leptin, food consumption, and strategies to reduce appetite.

When it comes to the problem of obesity, Dr. Jenkinson views it as a major health and economic issue that could lead to the collapse of healthcare systems. He highlighted the prevalence of obesity-related conditions such as type 2 diabetes, high blood pressure, sleep apnea, joint problems, and an increased risk for cancer.

Leptin, a hormone secreted by fat cells, regulates body weight by signaling the hypothalamus, the weight control center of the brain. However, certain foods can block leptin signals, such as sugar, refined carbohydrates, and processed foods, which increase insulin levels and block leptin.

Dr. Jenkinson emphasized that the concept of calories alone is not an effective approach to weight loss. Instead of focusing on calorie counting, he suggested avoiding foods that negatively impact insulin, which can shift the weight set point downward without significant effort.

In terms of exercise, Dr. Jenkinson explained that intense exercise can burn calories, but it can also lead to increased hunger and decreased metabolic rate if not balanced with calorie restriction. He recommended a combined approach of calorie restriction and intense exercise to achieve effective weight loss.

This interview with Dr. Andrew Jenkinson has been edited for clarity and length.

Dr. Andrew Jenkinson is a Consultant in Bariatric (Weight Loss) and General Surgery at University College London Hospital and the author of “Why do we eat (overeating)?” and “How to eat (and still lose weight).”