A Cochrane review has shown that certain types of insulin can remain effective when stored at room temperature for several months, offering a practical solution for diabetes treatment in areas without stable refrigeration. This finding is particularly crucial for people with diabetes in low- and middle-income countries, as well as those affected by conflict, natural disasters, and environmental challenges.
Insulin storage options have been highlighted in the review, which summarizes the results of various studies investigating the effects of storing insulin outside the refrigerator. It was found that unopened vials and cartridges of certain types of human insulin can be stored for extended periods at temperatures up to 25°C and 37°C without any clinical consequences or loss of insulin activity. This has significant implications for people living in areas where access to refrigeration is limited.
Dr. Bernd Richter led a research team that conducted a comprehensive study on insulin stability under different storage conditions. The review analyzed 17 studies and found consistent insulin efficacy at temperatures ranging from 4°C to 37°C, providing reassurance that alternatives to powered cooling of insulin are possible without compromising its stability.
The study also identified areas for future research, such as better understanding the efficacy of insulin after storage under different conditions, studies of mixed insulin, effects of movement on insulin pumps, contamination of opened vials and cartridges, and cold environmental conditions.
The study was funded by the World Health Organization.
Source: scitechdaily.com
