New Study Finds COVID-19 Vaccination Does Not Increase Risk of Miscarriage

A study by Boston University researchers found no increased risk of miscarriage associated with the COVID-19 vaccine among individuals planning a pregnancy. This encouraging evidence supports the safety of preconception vaccination and is consistent with health authorities’ recommendations for vaccination of people planning pregnancy.

The new study is the first to prospectively assess the relationship between bias and bias. COVID-19 (new coronavirus infection) We found that vaccinating both partners and having a miscarriage slightly reduced the risk of miscarriage among vaccinated partners trying to conceive.

In many studies, It is shown COVID-19 vaccines do not cause infertility or increase the risk of pregnancy-related problems, including miscarriage.Despite this evidence, people still on guard About the potential negative effects of vaccines on pregnancy.

A recent study conducted by researchers at the Boston University School of Public Health (BUSPH) provided more comprehensive information about the safety of COVID-19 vaccines for individuals considering pregnancy.

It was published in the magazine human reproductionthe study found no increased risk of early or late miscarriage as a result of either the man or the woman’s partner receiving the COVID-19 vaccine before pregnancy.

Insights from new research on pre-pregnancy vaccine safety

This study is the first to assess the risk of early miscarriage (<8 weeks gestation) following preconception COVID-19 vaccination, and the first to assess vaccination and miscarriage in men. The researchers hope these results will be useful information for individuals planning pregnancy and health care providers.

“These findings should be replicated in other populations, but are reassuring for couples planning pregnancy,” says lead author Jennifer Eland, an epidemiology doctoral student at BUSPH at the time of the study. .

Study details and results

For this study, Yland and colleagues analyzed survey data on COVID-19 vaccination and miscarriage among male and female participants of the BUSPH-based Online Pregnancy Study (PRESTO). National Institutes of Health– A funded study that enrolls women who wish to become pregnant and follows them from before pregnancy until 6 months after giving birth. Participants in this new analysis included 1,815 women in the United States and Canada who were followed in the study from December 2020 to November 2022. They were observed from the first positive pregnancy test until miscarriage or other event (e.g. induced abortion, ectopic pregnancy) occurred. , or 20 weeks of pregnancy)—whichever comes first.

Among female participants, 75% had received at least one dose of a coronavirus vaccine before becoming pregnant. Almost a quarter of pregnancies led to miscarriage, 75% of which occurred before 8 weeks of pregnancy, but there was no increased risk.

The risk of miscarriage was 26.6% for unvaccinated female participants, 23.9% for female participants who received one dose of vaccine before pregnancy, and 24.5% for female participants who completed the full first dose before pregnancy. and 22.1% among female participants who completed the vaccination series. 20.1% of women received only one dose of the two-dose vaccine three months before pregnancy.

“The miscarriage rate among vaccinated people was not only comparable to that among PRESTO participants who became pregnant before the pandemic, but also that the risk of miscarriage among vaccinated people was higher than that of unvaccinated people. “Our data showed that it was slightly lower than the previous year,” Yland said.

Federal health officials continue to recommend COVID-19 vaccination for people planning pregnancy, emphasizing that the benefits of COVID-19 vaccination outweigh the potential risks of vaccination before or during pregnancy. ing.

Reference: “Prospective Cohort Study of Preconception COVID-19 Vaccination and Miscarriage” Jennifer J Yland, Amelia K Wesselink, Annette K Regan, Elizabeth E Hatch, Kenneth J Rothman, David A Savitz, Tanran R Wang, Krista By F Huybrechts, Sonia Hernández-Diaz, Michael L. Eisenberg, Lauren A. Wise, October 20, 2023. human reproduction.
DOI: 10.1093/hamrep/dead211

The study was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the National Institute of Allergy and Infectious Diseases, and the National Science Foundation.

Source: scitechdaily.com

An alarming increase in unnoticed deaths in England

Research in England and Wales shows an alarming increase in the number of decomposing bodies found, which is linked to social isolation and indicates a breakdown in social support systems, particularly among men.

Exploratory research has revealed worrying trends in England and Wales. This means that an increasing number of people are being found dead or decomposed.

This study Journal of the Royal Society of Medicinesuggesting an association between increased social isolation and these deaths; COVID-19 (new coronavirus infection) Pandemic.

The study was authored by a team led by Dr. Lucinda Hiam. oxford university and Dr. Theodore Estrin-Cerluis, Registrar of Histopathology at Imperial College NHS Healthcare Trust.

Researchers analyzed data from the Office for National Statistics (ONS) to identify deaths where bodies were found decomposed. They used new proxies with deaths coded as R98 (“neglected death”) and R99 (“other unclear causes of death”) according to the International Classification of Diseases (ICD-10) and previous versions. did. “Unspecified death.”

amazing discovery

The study found that between 1979 and 2020, there was a steady increase in ‘unspecified deaths’, or deaths of people found decomposed, for both men and women. Male deaths exceed those of females, and male deaths increased significantly from the 1990s to the 2000s, when overall mortality rates were rapidly improving. The authors said the increase in deaths found in decomposing conditions, especially in men, was a worrying trend.

“Many people would be shocked to find out that someone could lie dead in their home for days, weeks, or even longer, without anyone in their community raising the alarm,” Estrin said. Dr. Serrui says: “The increase in people found dead and in decomposing conditions suggests that there was a broader societal breakdown in both formal and informal social support networks even before the pandemic. and warrants urgent further investigation.”

The study’s authors call on national and international authorities to consider measures to make it easier to identify deaths when people’s corruption is more easily detected in routine data.

Reference: ‘Deadly Silence: Why are the number of people found decomposing in England and Wales increasing?’ Lucinda Higham, Theodore Estrin-Cerlouis, Danny Doring, Martin Mackie , by John Minton, November 20, 2023, Journal of the Royal Society of Medicine.
DOI: 10.1177/01410768231209001

Source: scitechdaily.com

Expecting an Increase in IT Budgets in 2024, Though Startups May Face Tough Conditions

I think most People would agree that 2023 was a difficult time for startups. Many layoffs occurred as companies struggled to move from growth to profitability. On the other hand, sales cycles were becoming longer and many startups were struggling to grow at a decent pace.

As we start to see that the economic indicators are starting to improve a little bit.
calming inflation,
cost of money You might think 2024 might be a better year if currencies weaken and headwinds for most currencies subside.

necessarily.

We’re entering a new era, one in which money won’t flow as freely, and according to the experts we spoke to, it won’t be coming back anytime soon. This means startups that don’t have enough capital now may continue to struggle in 2024, and flipping the calendar won’t change that.

What does that mean for startups heading into 2024? It means they need to prove their worth more than ever. This means you need enough cash to survive long sales cycles. That means he will have to fight for a piece of the corporate budget, and perhaps 2024 could be a year much like his 2023.

Budget outlook

A good starting point for budget discussions is what the proposed budget looks like. Analyst firms like IDC and Gartner forecast IT spending each year, but they typically adjust throughout the year as reality becomes clearer.

IDC predicts growth of 6.8%, up from 5% last year. This figure covers hardware, software, and services, but excludes communications spending. Gartner, on the other hand, predicts a slightly higher rate of 8.2%.

The overall upward trend should be good news for startups looking to corporate buyers to lift their business. But his Gartner analyst John-David Lovelock, who tracks IT budgets, says that while 2023 was a year of increased efficiency, it won’t just end in the new year.

Source: techcrunch.com

A16z-funded Apex Space inaugurates new facility to increase satellite bus production

when apex space The company, which came out of stealth last October, had the provocative goal of eliminating “new bottlenecks” plaguing the space industry by building satellite buses at scale.

To get there, Apex announced today that it will open a new headquarters and production facility in California and eventually scale up to manufacture 50 satellite platforms per year. Apex CEO Ian Cinnamon said in a statement that the new 46,000-square-foot facility is “vital to meeting customer demand.”

“Our customers want spacecraft with short lead times, and Factory One delivers that,” he said.

Apex wants to disrupt one of the most entrenched parts of the space industry. Satellite buses are generally made to order, which means their costs are very high and delivery times are very long. However, major changes in the industry, such as the reduction in the cost of mass launches into space, have opened up a whole new group of customers looking to send payloads into orbit.

The company plans to initially offer three satellite bus classes. One is a smaller 100 kilogram bus called Aries, which can support a payload of up to 100 kilograms. The motorcoach, called Nova, can accommodate a payload of up to 230 kg. The even larger bus “Comet” can carry up to 500 kilograms. Apex plans to fly the first Aries on SpaceX’s Transporter 10 rideshare mission, scheduled for the first quarter of next year.

Apex aims to expand the factory in the coming years. The company currently plans to deliver five Aries platforms to customers in 2024 and aims to increase production to 20 aircraft by 2025.

The company has raised at least $23.5 million in seed and Series A funding from backers including Andreessen Horowitz and Shield Capital.

Source: techcrunch.com