Tag Archives: vaccination

Doctors Warn of Rising Tetanus Cases Due to Declining Vaccination Rates

Posted on by
Reply

Health professionals are sounding the alarm over potential rises in tetanus, commonly known as bone-lock. Symptoms may take anywhere from 3 to 21 days to manifest and can include severe muscle spasms leading to breathing difficulties. Once the infection establishes itself, sufferers often experience jaw clenching, resembling a fixed grin, coupled with painful back muscle contractions.

“The effects are alarming,” stated Dr. Mobeen Rathore, Chief of Pediatric Infectious Diseases at the University of Florida Jacksonville School of Medicine.

The bacterium Clostridium tetani is commonly found in soil and fertilizers. Infections can arise from puncture wounds, and the illness can persist for several weeks, complicating treatment.

Treatment is not only challenging but also expensive. A case reported by the CDC highlighted an unvaccinated 6-year-old in Oregon who incurred nearly $1 million in medical expenses due to tetanus in 2019.

Dr. Rasool emphasized the stark difference in costs, likening vaccination expenses to intensive care costs.

“It’s a fraction of a cent compared to hundreds of thousands of dollars,” Rasool remarked. “It’s a hefty price to pay.”

This year, he diagnosed an unvaccinated 9-year-old in Laseau, Florida, who exhibited signs of muscle spasms reminiscent of warnings from his medical school tetanus wards—dark, quiet spaces meant to minimize sensory overload.

“Even minimal noise can provoke seizures in many cases,” Rasool explained.

Light sensitivity, or photophobia, can also lead to painful spasms and airway muscle contractions.

In the bustling ICU, bright lights and alarms limited Rasool’s ability to reduce patient stimulation. The 9-year-old was sedated, intubated, and treated with tetanus immune globulin antibodies alongside vaccination to mitigate future risks.

The child spent a challenging 37 days in the hospital.

“Before widespread immunization, we witnessed increased tetanus cases and a higher mortality rate,” noted Dr. Matthew Davis, Chief Scientific Officer at Nemours Children’s Health.

John Johnson, a vaccination and epidemic prevention expert with Médecins Sans Frontières, operates in regions like the Democratic Republic of Congo, where tetanus remains a pressing concern. In 2022 alone, 540 cases were reported in the DRC according to the World Health Organization.

“This disease is trivially preventable,” Johnson lamented. “One case of tetanus in the U.S. would be a regrettable anomaly; there’s no reason for this illness to reappear.”

“My jaw has completely locked.”

Post childhood vaccination, booster doses are advised every decade for adults, yet many remain unaware of this necessity.

Nikki Arellano, aged 42, hadn’t received a tetanus shot since 2010. After a minor injury while assisting a friend, she began experiencing jaw pain during lunch. Soon, she found herself unable to open her mouth.

“My jaw completely locked shut,” said Arellano from Reno, Nevada. “Despite heavy sedation and pain relief in the emergency room, nothing worked.”

Arellano was diagnosed with tetanus and admitted for IV antibiotics.

“With each episode, I heard a loud beeping response. The muscle contractions felt explosive,” she recounted.

Initially, spasms began in one arm, spreading rapidly. “My back curved painfully,” she shared.

Arellano then struggled to swallow and feared her airway was at risk.

“It was terrifying,” she added.

After nearly a week in the hospital, Arellano continues her recovery process.

Climate Change Heightens Tetanus Risks

Natural disasters like hurricanes, tornadoes, and floods heighten the risks of tetanus outbreaks. Injuries from debris can facilitate bacterial infection.

“As global temperatures rise, the frequency and severity of extreme weather events are increasing,” stated Christy Ebi, an epidemiologist at the University of Washington. “More flooding translates to fewer vaccinations for diseases like tetanus, heightening public vulnerability.”

States severely affected by natural disasters, such as Florida, Texas, and Kansas, have reported significant drops in tetanus vaccination rates, according to NBC News data.

Source: www.nbcnews.com

Coronavirus Poses Greater Heart Disease Risk for Children Than Vaccination

Posted on by
Reply

Vaccination against covid-19 is safer than infection

Juan Monino/Getty Images

Recent findings highlight that vaccinating children is more beneficial than exposing them to the coronavirus. A comprehensive study involving nearly 14 million children revealed that the likelihood of experiencing serious, albeit uncommon, side effects related to the heart and blood vessels was considerably greater following an infection compared to a vaccination.

Specifically, children aged 5 to 18 experienced 17 additional infections per 100,000 with inflammatory conditions such as Kawasaki disease in the six months after contracting SARS-CoV-2, as opposed to other periods. Conversely, among children first vaccinated with the Pfizer/BioNTech mRNA vaccine, infections per 100,000 dropped by almost two.

Myocarditis, which is inflammation of the heart muscle, resulted in over two extra cases per 100,000 individuals in the six months post-infection. In comparison, there was less than one additional case among vaccinated individuals, indicating that the risk of myocarditis is more than double following infection relative to vaccination.

A report highlighting a new coronavirus infection causing myocarditis has been made known. As early as April 2020, reports began surfacing even after vaccinations commenced in December. Vaccines associated with myocarditis tend to present milder symptoms, particularly in young men, and most individuals recover swiftly.

The uncommon side effects of this vaccine have garnered substantial media focus and stirred significant concern, contributing to delays in introducing routine childhood vaccinations in the UK until April 2022.

The latest findings reinforce earlier research indicating that vaccinated children face a lower risk of myocarditis compared to their unvaccinated peers, despite the rarity of this side effect. A majority of children contracted the virus, placing them at an elevated risk of adverse effects.

“It’s important to note that severe complications are highly uncommon among children and adolescents in general,” states Angela Wood from Cambridge, UK, a part of the HDR UK regional network. “Nevertheless, evidence suggests that the risk is generally higher following COVID-19 compared to vaccination.”

Wood’s team evaluated data from the UK’s National Health Service (NHS) encompassing approximately 14 million children under 18 from January 2020 to December 2021. During the latter half of this timeframe, 3.9 million children received the Pfizer/BioNTech vaccine, while 3.4 million were diagnosed with COVID-19 for the first time. Subsequent periods could not be analyzed due to insufficient testing.

This approach does have its limitations. For instance, the data does not indicate whether children who experienced these complications made a full recovery, and many mild COVID-19 cases amongst children may not have been formally recognized. “However, despite these constraints, the scale of the data and the comprehensive connection across all NHS data instills great confidence in our overall conclusions today,” says Wood.

“It’s crucial to understand that findings relevant to the strain of the coronavirus prevalent during the peak of the pandemic may differ for the current strain,” advises William Whiteley from the University of Edinburgh, UK, who was not involved in the study. His team previously reported that COVID-19 vaccines reduce the risk of heart attacks and strokes for at least six months post-vaccination.

The fact that nearly all individuals, apart from very young children, now possess some level of immunity to COVID-19 means they may respond differently to both booster shots and reinfections, according to team members including Peer Hardelid from University College London. “Ongoing research is essential,” she emphasizes.

Topic:

Source: www.newscientist.com

Hepatitis B Vaccination Linked to Reduced Diabetes Risk

Posted on by
Reply

Daily vaccinations for hepatitis B are administered worldwide

Mehmet Salih Guler / Getty Images

The hepatitis B vaccine not only prevents infection but also appears to lower the chances of developing diabetes.

In most countries, infants receive this vaccine routinely, typically as part of a three-dose series. In the US, it was incorporated into vaccination schedules in 1991. By 2018, around 30% of adults were fully vaccinated.

Researchers previously noted that vaccination may decrease diabetes risk. This is related to hepatitis B, which infects the liver and is transmitted through blood, semen, and vaginal fluids – impairing the liver’s ability to manage glucose. Elevated blood sugar levels can lead to diabetes.

However, earlier studies didn’t investigate whether vaccination could lower diabetes risk in individuals who were not infected with hepatitis B.

To address this gap, Nhu-Quynh Phan from Taipei Medical University in Taiwan and her team examined health data from over 580,000 people across the US, Europe, Africa, Latin America, the Middle East, and Asia-Pacific. These records averaged almost four years for each individual, covering the period from 2005 to 2023.

Participants aged 18 to 90 had no types of diabetes and were not infected with hepatitis B. About half were vaccinated, determined by measuring virus-specific antibodies in their blood.

The study revealed that diabetes prevalence among vaccinated individuals was 15% lower than in the unvaccinated group, with most cases being type 2 diabetes, the most prevalent form. The findings will be shared at the upcoming annual meeting of the Diabetes Association in Vienna, Austria.

This observational study also indicated a dose-response correlation. Participants with higher levels of hepatitis B-specific antibodies were less likely to develop diabetes compared to those with lower levels. Variations in antibody levels might correlate with the number of vaccinations received, timing of immunization, or individual immune responses.

No participants were purposefully infected with hepatitis B, suggesting that vaccination not only wards off the virus but may also lower diabetes risk, Fan notes. One explanation could be that vaccines help alleviate chronic inflammation damaging the liver and pancreas, which produce hormones like insulin regulate blood sugar levels.

Nonetheless, researchers cannot dismiss the theory that some protective benefits of vaccines might stem from their role in preventing infections, she adds. They are keen to investigate credible pathways and how mouse models can elucidate distinctions between diabetes types, Fan states.

Vaccinated individuals might also engage in healthier lifestyle choices, such as maintaining a nutritious diet and staying active. “Those likely to get vaccinated often exhibit greater awareness of health,” states Albert Osterhouse from the University of Veterinary Medicine in Hanover, Germany.

The research team considered factors including participants’ age, gender, and lifestyle choices like smoking, along with conditions such as obesity and hypertension. However, Osterhouse emphasizes the difficulty in ruling out the impact of these variables.

Topic:

Source: www.newscientist.com

Many in the UK contracting severe coronavirus infections in summer due to lack of vaccination

Posted on by
Reply

A coronavirus vaccine is being administered at Epsom Racecourse in Surrey, England.

PA Image/Alamy

Around 7,000 people in the UK would have avoided dying or being hospitalized from coronavirus in the summer of 2022 if they had been fully vaccinated against the virus, a major study has found. This is the first time that the health impact of hesitancy to get a COVID-19 vaccine has been calculated on a national basis.

Since the emergence of the Omicron variant, covid-19 vaccines are less effective at preventing people from getting infected, but they still reduce the risk of dying or needing hospitalization from the virus.

katherine sudlow Researchers at the University of Edinburgh in the UK used national health service data to determine how much vaccination would reduce hospitalizations and deaths in the summer of 2022, when most COVID-19 restrictions had ended. We investigated whether it had an impact on

Sudlow's team included data from June 1 to September 30, 2022, spanning the wave of coronavirus infections that peaked in July. During this period, 40,000 people died or required hospitalization due to the virus, all of which were classified as serious health hazards.

The team then looked at people who have received the recommended number of COVID-19 vaccines and boosters (for example, four doses for people 75 and older by that point) and those who have received fewer than the recommended number of doses. They compared rates of severe outcomes among people who received the vaccine or booster immunization. Not at all.

People who have not been fully vaccinated are more likely to develop severe disease than people who are fully vaccinated, and the exact increased risk depends on age. For example, people over the age of 75 are about three times more likely to develop severe illness from COVID-19 if they have not been fully vaccinated.

The researchers calculated that if everyone in the UK had been fully vaccinated, there would have been around 7,000 fewer deaths and hospital admissions. “Fully immunizing people will reduce adverse outcomes for society as a whole,” Sudlow said.

One caveat is that this study was not a randomized trial, which is the best medical evidence, but simply observed a correlation between vaccination status and outcome, which could bias the results. The fact is that there is, he said. stephen evans At the London School of Hygiene and Tropical Medicine.

Nevertheless, he says the results of studies on the vaccine's effectiveness are broadly consistent with previous randomized trials. “Their approach is a reasonable one.”

topic:

Source: www.newscientist.com

New Study Finds COVID-19 Vaccination Does Not Increase Risk of Miscarriage

Posted on by
Reply

A study by Boston University researchers found no increased risk of miscarriage associated with the COVID-19 vaccine among individuals planning a pregnancy. This encouraging evidence supports the safety of preconception vaccination and is consistent with health authorities’ recommendations for vaccination of people planning pregnancy.

The new study is the first to prospectively assess the relationship between bias and bias. COVID-19 (new coronavirus infection) We found that vaccinating both partners and having a miscarriage slightly reduced the risk of miscarriage among vaccinated partners trying to conceive.

In many studies, It is shown COVID-19 vaccines do not cause infertility or increase the risk of pregnancy-related problems, including miscarriage.Despite this evidence, people still on guard About the potential negative effects of vaccines on pregnancy.

A recent study conducted by researchers at the Boston University School of Public Health (BUSPH) provided more comprehensive information about the safety of COVID-19 vaccines for individuals considering pregnancy.

It was published in the magazine human reproductionthe study found no increased risk of early or late miscarriage as a result of either the man or the woman’s partner receiving the COVID-19 vaccine before pregnancy.

Insights from new research on pre-pregnancy vaccine safety

This study is the first to assess the risk of early miscarriage (<8 weeks gestation) following preconception COVID-19 vaccination, and the first to assess vaccination and miscarriage in men. The researchers hope these results will be useful information for individuals planning pregnancy and health care providers.

“These findings should be replicated in other populations, but are reassuring for couples planning pregnancy,” says lead author Jennifer Eland, an epidemiology doctoral student at BUSPH at the time of the study. .

Study details and results

For this study, Yland and colleagues analyzed survey data on COVID-19 vaccination and miscarriage among male and female participants of the BUSPH-based Online Pregnancy Study (PRESTO). National Institutes of Health– A funded study that enrolls women who wish to become pregnant and follows them from before pregnancy until 6 months after giving birth. Participants in this new analysis included 1,815 women in the United States and Canada who were followed in the study from December 2020 to November 2022. They were observed from the first positive pregnancy test until miscarriage or other event (e.g. induced abortion, ectopic pregnancy) occurred. , or 20 weeks of pregnancy)—whichever comes first.

Among female participants, 75% had received at least one dose of a coronavirus vaccine before becoming pregnant. Almost a quarter of pregnancies led to miscarriage, 75% of which occurred before 8 weeks of pregnancy, but there was no increased risk.

The risk of miscarriage was 26.6% for unvaccinated female participants, 23.9% for female participants who received one dose of vaccine before pregnancy, and 24.5% for female participants who completed the full first dose before pregnancy. and 22.1% among female participants who completed the vaccination series. 20.1% of women received only one dose of the two-dose vaccine three months before pregnancy.

“The miscarriage rate among vaccinated people was not only comparable to that among PRESTO participants who became pregnant before the pandemic, but also that the risk of miscarriage among vaccinated people was higher than that of unvaccinated people. “Our data showed that it was slightly lower than the previous year,” Yland said.

Federal health officials continue to recommend COVID-19 vaccination for people planning pregnancy, emphasizing that the benefits of COVID-19 vaccination outweigh the potential risks of vaccination before or during pregnancy. ing.

Reference: “Prospective Cohort Study of Preconception COVID-19 Vaccination and Miscarriage” Jennifer J Yland, Amelia K Wesselink, Annette K Regan, Elizabeth E Hatch, Kenneth J Rothman, David A Savitz, Tanran R Wang, Krista By F Huybrechts, Sonia Hernández-Diaz, Michael L. Eisenberg, Lauren A. Wise, October 20, 2023. human reproduction.
DOI: 10.1093/hamrep/dead211

The study was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the National Institute of Allergy and Infectious Diseases, and the National Science Foundation.

Source: scitechdaily.com

UK News: Government Urges Targeted Vaccination for Individuals Most Vulnerable to Gonorrhea and Monkeypox

Posted on by
Reply

British scientists are urging the government to implement routine vaccines for those most susceptible to monkeypox and gonorrhea, marking the world’s first immunization program against the latter. The Joint Committee on Vaccination and Immunization (JCVI) has recommended to Rishi Sunak that both programs be offered opportunistically to those who need it most.

Professor Andrew Pollard, Chair of the JCVI, expressed, “The UK’s gonorrhea prevention program is a world-first and is expected to significantly reduce gonorrhea levels, which are currently at record highs. In addition, we recommend implementing routine monkeypox vaccinations to prevent a recurrence of the outbreaks seen in early 2022. Both vaccines should be offered to those at highest risk.”

The JCVI also advises that recommended vaccination programs against gonorrhea should primarily target gay and bisexual men and other men who have sex with men, who are at higher risk of contracting the disease. This comes in light of a 50.3% increase in gonorrhea diagnoses in 2022 compared to 2021, totaling 82,592 cases, according to Health and Safety Executive sexually transmitted infection (STI) statistics. Additionally, the number of gonorrhea cases in the UK last year was reported to be up by more than a fifth from pre-pandemic levels.

Greg Fell, chairman of the Association of Public Health Officers, told Sky News: “The recent rise in sexually transmitted infections such as gonorrhea is extremely worrying and today’s advice from the JCVI is undoubtedly a prudent course of action. However, this increase in numbers is also a result of more people visiting clinics and other diagnostic services for testing, which has led to higher demand for sexual health services.”

“As we said in June, we are concerned that the current level of funding for sexual health services provided by public health grants in England will not be able to meet this increase in demand. The new vaccination program will therefore be planned with this in mind and backed by appropriate funding and resources to ensure that existing services remain intact and people can be vaccinated in a timely and dignified manner as needed.”

Source: news.sky.com