New Study Reveals Benefits of Regular Grape Consumption for Healthy Skin

Consuming grapes may enhance the skin’s protective barrier against environmental damage by altering gene activity, according to a groundbreaking study conducted by Western New England University.

Grape phytochemicals interact with the microbiome, influencing gene expression and promoting skin health. Image credit: Nicky Pe.

Grapes are rich in a variety of natural compounds known for their antioxidant and anti-inflammatory properties, making them a valuable addition to your diet.

Key components include quercetin, anthocyanins, and the well-known resveratrol.

Clinical research has linked regular grape consumption to various health benefits, including enhanced cardiovascular health, reduced inflammation, improved bowel function, and better cognitive performance in older adults.

“We are increasingly confident that grapes serve as a superfood, mediating nutritional genomic responses in humans,” stated Professor John Pezzuto, the study’s lead author from Western New England University.

“This was particularly evident in the body’s largest organ, the skin.”

“Notably, we observed changes in gene expression that indicated improved skin health.”

“Furthermore, grape consumption likely influences gene expression in other vital organs, such as the liver, muscles, kidneys, and even the brain.”

“This research enriches our understanding of how whole foods, like grapes, impact overall health.”

“It’s thrilling to be part of a post-genomics era, where we can visualize the complex matrices that illustrate nutritional genomic responses.”

The study involved human volunteers who consumed the equivalent of three servings of whole grapes daily for two weeks.

Gene expression in the skin was measured both before and after grape ingestion, with and without exposure to low-dose ultraviolet (UV) radiation.

The findings displayed variations in gene expression between individuals, indicating unique responses to both grape consumption and UV exposure.

More significant changes were observed when UV exposure coincided with grape consumption.

Thus, while individual responses varied, all participants experienced notable changes in gene expression after eating grapes.

By identifying functional similarities in gene expression changes post-grape consumption, researchers noted increased keratinization of the skin, a process that forms a protective barrier against environmental harm.

This conclusion was further reinforced by exposing the skin to low doses of UV radiation and measuring malondialdehyde, an oxidative stress marker, which decreased with grape consumption.

“Our results, primarily based on transcriptomic data and theoretical protein-protein interactions, support the conclusion that grape consumption benefits skin health,” the researchers confirmed.

“Of course, other factors such as non-coding RNA and epigenetics also play a role and require further exploration.”

For more details, refer to their published paper in ACS Nutrition.

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Asim Dave et al. Inter- and intra-individual variation in gene expression in human skin after grape consumption and/or exposure to ultraviolet radiation. ACS Nutritional Science, published online on May 13, 2026. doi: 10.1021/acsnutrsci.6c00003

Source: www.sci.news

Grape seeds dating back 60 million years found in Colombia

Paleobotanists have described nine new species of the Vitaceae family. Vitaceae It is based on fossil seeds from four tropical palaeoflora sites, dating back 60 to 19 million years. Rithuva Susmani This new species, discovered in Colombia, is the oldest evidence of a Vitaceae plant in the Western Hemisphere.

Rithuva Susmani From the Paleocene of Colombia. Scale bar – 1 mm. Image courtesy of Herrera et al., doi: 10.1038/s41477-024-01717-9.

Soft tissues, like those of fruit, rarely preserve as fossils, so scientists often learn more about ancient fruits through their seeds, which fossilize more easily.

The oldest known grape seed fossils were found in India and date back to 66 million years ago.

“We always think about animals, we think about dinosaurs, because they were the ones most affected, but the extinction also had a big impact on plants,” said Dr. Fabianie Herrera, a paleobotanist at the Field Museum.

“The forest has reset itself and changed its plant composition.”

Dr Herrera and his colleagues hypothesize that the extinction of the dinosaurs may have prompted changes in the forests.

“Large animals like dinosaurs are known to alter the ecosystems around them,” said Dr. Monica Carvalho, a paleobotanist at the University of Michigan Museum of Paleontology.

“We think that if large dinosaurs roamed the forests, they would likely have cut down trees and maintained more open forests than we have today.”

“But with no large dinosaurs around to cut down forests, some tropical forests, including those in South America, became densely wooded, with layers of trees forming an understory and a canopy.”

“These new dense forests provided an opportunity, and the fossil record shows that around this time we start to see an increase in plants that use vines to climb trees, like grapes,” Dr Herrera said.

“The diversification of birds and mammals in the years following the extinction may also have helped spread grape seeds.”

The researchers examined fossilized grape seeds from the 60-million-year-old Bogotá Formation in Colombia, the 41-million-year-old Tonosi Formation in Panama, the 28-million-year-old Máncora Formation in western Peru, and the 19-million-year-old Cucaracha Formation, exposed at the Gaillard Cut in the Panama Canal.

They were able to identify at least nine new species of the Vitaceae family, including: Rithuva SusmaniThis provides the oldest evidence of grapes in the Western Hemisphere.

“This new species is important as it confirms the South American origin of the group that includes the common grape vine. Grapes “It evolved,” says Dr Gregory Staal, a paleobotanist at the National Museum of Natural History.

“These are the oldest grapes ever found in this region, millions of years younger than the oldest found on the other side of the world,” Dr Herrera said.

“This discovery is important because it shows that grapes really started to spread around the world after the dinosaurs went extinct.”

The new species' place in the grapevine family tree indicates that its evolutionary journey has been a checkered one.

“The fossil record shows that grapevines are very resilient plants,” Dr Herrera said.

“They are an endangered group in the Latin American region, but they have been able to adapt and survive in other parts of the world.”

“Given the mass extinctions facing the Earth today, studies like this one are valuable in revealing patterns about how biodiversity crises will unfold.”

“But the other thing I like about these fossils is that these tiny, humble seeds can tell us a lot about forest evolution.”

of study Published in the journal Natural plants.

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F. Herrera othersCenozoic Vitaceae seeds reveal a long history of extinction and dispersal in the Neotropics. Natural plantsPublished online July 1, 2024; doi: 10.1038/s41477-024-01717-9

Source: www.sci.news