RFK Jr. supports Vitamin A treatment for select measles patients

West Texas doctors are seeing measles patients whose illness is complicated by alternative therapy approved by vaccine skeptics, including health secretary Robert F. Kennedy Jr.

Parents in Gaines County, Texas, are at the heart of the outbreak of turbulent measles, many of which have become increasingly repurposed and unproven treatments to protect children who have not been vaccinated against the virus.

One of those supplements is Vitamin A, which Kennedy advertises as a miraculous treatment for measles. Doctors at Covenant Children’s Hospital in Lubbock, Texas, say they have treated a small number of children who were given so much vitamin A, which has signs of liver damage.

Dr. Summer Davis, who cares for children with acute illnesses at the hospital, said some of them had been receiving unsafe supplements for weeks to prevent measles infection.

“We were sick for just a few days, five days, five days, and five days, but we had been taking it for about three weeks,” Dr. Davis said.

Doctors may manage severe measles by administering high doses of vitamin A in hospitals, but experts do not recommend taking it without supervision from a doctor. Vitamin A is not an effective way to prevent measles. However, two doses of measles, mumps and rubella vaccines are about 97% effective.

At high doses, vitamin A can cause liver damage. Dry skin peeled skin. Hair loss; and in rare cases, seizures and com sleep. So far, doctors at a hospital in West Texas have said they have seen patients with high yellow skin and liver enzymes in both blood tests for both liver signs.

Many of these patients were in hospital due to severe measles infection. The doctor only discovered liver damage after regular lab work.

As of Tuesday, the outbreak that began in January had spread to more than 320 cases in Texas. Forty patients were hospitalized and one child died.

Nearby New Mexico County, the virus has suffered 43 illnesses and two hospitalised. Seven confirmed cases in Oklahoma are also linked to outbreaks.

Local doctors and health officials are increasingly concerned about the growing popularity of unproven treatments to prevent and treat measles. They fear that people will delay serious treatment and refuse vaccination, the only proven way to prevent measles infection.

Alternative medicine has always been popular in Gaines County. Many of the large Mennonite communities in areas where most cases are clustered are avoiding interaction with the healthcare system and adhere to a long tradition of natural therapy.

Health officials said the popularity of Vitamin A’s recent use of measles could go back to a Fox News interview with Kennedy.

in Opinion essay In the Washington Post Tuesday afternoon, Kevin Griffith, who was the communications director for the Centers for Disease Control and Prevention until last week, wrote that he had resigned to handle Kennedy’s outbreak.

“In my last few weeks at the CDC, I saw a career infectious disease expert being tasked with spending valuable time wasting data searches to support Kennedy’s preferred treatment,” writes Griffith.

A few weeks after the interview with Fox News, Drugstore In West Texas, I had a hard time maintaining vitamin A and cod liver oil supplements on my shelf. “I didn’t hear anything about Vitamin A until he said that on TV,” said Katherine Wells, director of public health at Lubbock.

One local doctor, appointed as one of the doctors that Kennedy said in an interview with Fox News, opened a makeshift clinic in Gaines County, and began eliminating a variety of treatments, including vitamin A supplements, to treat active incorrect cases and prevent infection.

Dr. Davis said he suspected that the majority of the children she treated had taken vitamins at home.

Experts say Vitamin A can play an important role in the “advocacy care” provided by doctors to patients with severe measles infection.

Dr. William Schaffner, an infectious disease expert at Vanderbilt University Medical Center, works by replenishing physical reservoirs that have been depleted by viruses that strengthen the immune system.

In hospitals, doctors only give measles children two vitamins, usually over two days, and “adjusting very carefully” the amount according to their age and weight, he said.

Dr. Schaffner emphasized that it is not a miraculous treatment of the virus, and that measles does not have antiviral drugs. Also, there is no reliable evidence that vitamin A can help prevent infection in children in the US, with extremely rare vitamin A defects.

In fact, giving children high doses of repeated vitamins is dangerous. Unlike other vitamins that are washed away from the body via urine, excess vitamin A accumulates in adipose tissue and is more likely to reach dangerous levels over time.

“I think this type of preventative use is particularly concerning,” said Dr. Lara Johnson, another doctor at Lubbock Hospital.

“When you’ve been taking it on your kids for weeks or weeks, you can have a cumulative toxicity impact.,” she added.

Dr. Johnson added that local doctors don’t always accurately reflect the amount of vitamins the label contains and are particularly concerned about parents’ dependence on over-the-counter supplements that can accept dosage recommendations from unverified sources.

Source: www.nytimes.com

Research on Dark Energy Supports the Evolving Theory

The Lambda-CDM (λCDM) model has been the basis of modern cosmology for some time, and it successfully explains the large-scale structure of the universe. It proposes that 95% of cosmos consists of dark matter (25%) and dark energy (70%). Dark energy, represented by the cosmic constant (λ), is thought to promote accelerated expansion of the universe, and maintains a constant energy density over time. However, new results from the dark energy research suggest a departure from this assumption, suggesting that dark energy may evolve over time.

This artist's impression shows the evolution of the universe, beginning with the Big Bang on the left. After that, you will see the microwave background of the universe. The formation of the first stars ends the dark ages of the universe, followed by the formation of galaxies. Image credit: M. Weiss/Harvard – Smithsonian Center for Astrophysics.

The Dark Energy Survey (DES) was carried out using a 570 megapixel energy-enhanced dark energy camera (decam) mounted on the NSF Víctor M. Blanco 4-M telescope from the NSF Neuroab program, Cerro Tololo Inter-American Observatory.

By obtaining data of 758 nights over six years, DES scientists mapped almost one-eighth area of ​​the sky.

The project employs multiple observation techniques, including supernova measurement, galaxy clustering analysis, and weak gravity lenses, to study dark energy.

Two important DES measurements, baryon acoustic vibration (BAO) and explosive star distance measurements (type IA supernova) track the enlarged history of the universe.

Bao refers to a standard cosmic ruler formed by early universe sound waves, with peaks spanning approximately 500 million light years.

Astronomers can measure these peaks over several periods of universe history to see how dark energy has expanded the scale over time.

“By analyzing 16 million galaxies, DES discovered that the measured BAO scale is actually 4% smaller than predicted by λCDM,” says Dr. Santiago Avila, an astronomer at the Center for Energy and Environmental Technology Research (CIEMAT).

Type IA supernova acts as a standard candle. In other words, the essential brightness is known.

Therefore, its apparent brightness is combined with information about the host's galaxy to allow scientists to perform accurate distance calculations.

In 2024, the DES team released the most extensive and detailed supernova dataset to date, providing highly accurate measurements of space distance.

New discoveries from the combined supernova data and BAO data independently confirm the anomalies seen in the 2024 supernova data.

By integrating DES measurements with cosmic microwave background data, researchers infer the properties of dark energy, and the results suggest that they evolve time.

When verified, this implies a dynamic phenomenon in which the cosmological constant, dark energy, is not ultimately constant and requires a new theoretical framework.

“The results are interesting as they suggest physics beyond the standard models of cosmology,” says Dr. Juan Mena Fernandez, a researcher at the Institute of Subatomic Physics and Cosmology.

“If more data supports these findings, we may be on the brink of a scientific revolution.”

Although current results are still inconclusive, future analyses incorporating additional DES probes such as Galaxy Clustering and weak lenses could enhance the evidence.

Similar trends have emerged from other major cosmological projects, such as Dark Energy Spectroscopy (DESI).

“We've seen a lot of experience in our research,” said Jesse Muir, a researcher at the University of Cincinnati.

“There's still a lot to learn and it's exciting to see how understanding evolves as new measurements become available.”

Team's paper It will be published in journal Physical Review d.

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TMC Abbott et al. (DES collaboration). 2025. Dark Energy Survey: Final Devalion Acoustic Vibrations and Impact on Cosmological Expansion Models from Supernova Data. Physical Review din press; Arxiv: 2503.06712

Source: www.sci.news

Recent Discovery of Messier 87 Black Hole Supports Einstein’s General Theory of Relativity

In April 2019, the Event Horizon Telescope (EHT) collaboration resolved the central black hole of the giant elliptical galaxy Messier 87 (M 87), known as M87*, the first-ever event horizon-scale black hole. I reported the image. . In a new paper, astronomers present new images of M87* from data collected by the Atacama Large Millimeter/Submillimeter Array (ALMA), the Greenland Telescope, and several other instruments within the EHT. doing. These new images show the shadow of his M87* as predicted by general relativity. Interestingly, the peak brightness of the ring is shifted by about 30 degrees compared to the first image. This is consistent with the theoretical understanding of fluctuations due to turbulent matter around a black hole.



The Event Horizon Telescope Collaboration has released new images of M87* from observations taken in April 2018, one year after the first observations in April 2017. The new observations reveal a familiar bright luminescent ring, the same size as the one originally observed. The brightest part of the ring has moved about 30 degrees to the 5 o'clock position compared to the 2017 image. Image credit: EHT Collaboration.

“A fundamental requirement of science is to be able to reproduce results,” says Dr. Keiichi Asada, an astronomer at the Institute of Astronomy and Astrophysics, Academia Sinica.

“The confirmation of the ring in a completely new data set is a major milestone for our collaboration and a strong indication that we are observing the shadow of a black hole and the matter orbiting around it. .”

An image of M87* taken in 2018 is strikingly similar to what astronomers saw in 2017.

They see bright rings of the same size, with a dark central area and one side of the ring brighter than the other.

Because M87*'s mass and distance do not increase appreciably over a human lifetime, general relativity predicts that the diameter of the ring will remain the same from year to year.

The diameter stability measured in the 2017-2018 images strongly supports the conclusion that M87* is well described by general relativity.

“One of the remarkable properties of a black hole is that its radius strongly depends on only one quantity: its mass,” said Dr. Nitika Yadrapalli-Yurku, a postdoctoral fellow at NASA's Jet Propulsion Laboratory.

“M87* is not a material that gains mass rapidly, so according to general relativity, its radius will change little throughout human history. We see our data confirm this prediction. That's very interesting.”

Although the size of the black hole's shadow did not change between 2017 and 2018, the location of the brightest region around the ring changed significantly.

The bright area rotated about 30 degrees counterclockwise and settled in the lower right part of the ring, at about the 5 o'clock position.

Historical observations of M87* with less sensitive arrays and a small number of telescopes also show that the shadow structure changes from year to year, but with low precision.

Although the 2018 EHT array cannot yet observe jets emerging from M87*, the black hole's axis of rotation predicted from the location of the brightest region around the ring is more consistent with the axis of jets seen at other wavelengths. Masu.

“The biggest change is that the brightness peak has moved around the ring, which is actually the first time in 2019 that “This is what we predicted when we announced the results.”

“According to general relativity, the size of the ring should remain approximately constant, but radiation from the turbulent and messy accretion disk around the black hole causes the brightest parts of the ring to move toward a common center. It wobbles around you.”

“The amount of wobble observed over time can be used to test theories about the magnetic field and plasma environment around the black hole.”

of new results appear in the diary astronomy and astrophysics.

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Collaboration with Event Horizon Telescope. 2024. The persistent shadow of M 87's supermassive black hole. I. Observation, Calibration, Imaging, and Analysis. A&A 681, A79; doi: 10.1051/0004-6361/202347932

Source: www.sci.news

Flipboard now supports ActivityPub as a federated app

Instagram Threads isn’t the only app participating in the decentralized social web. The decentralized social web includes Twitter/X rival Mastodon and other apps, and has added support for the new networking protocol ActivityPub. Currently, the social magazine app Flipboard is announcement It is also now integrated with ActityPub. In the initial phase, his selected Flipboard account will be discoverable and followable by millions of users on decentralized social apps, including Mastodon. Over time, all profiles on Flipboard will be available in the Fediverse, as this network of decentralized social apps is known.

The company announced its intention to join the Fediverse earlier this year. It started by integrating the app with His Mastodon via the API and setting up its own Mastodon server. flipboard.social, prior to full integration of ActivityPub. This gave Flipboard a feel for the world of decentralized social media and how users would react. It also gave Flipboard a way to stay connected to social media after Twitter/X increased API fees for third-party developers. unsustainable This is to allow more developers to continue working with the company.

The main purpose of the Flipboard app was to curate news and information from around the web into a social “magazine” that included links to articles, photos, and other social posts. As a result, we relied on Twitter as one of our sources of information. Things changed this year when Flipboard moved its Twitter integration to his Mastodon and another alternative social app, Bluesky. He also set up his own Mastodon server and began curating news from across the Commonwealth through an editorial “desk” focused on improving news discovery on Mastodon.

All of this is in preparation for making Flipboard itself a federated social app, a process that begins today.

Initially, Flipboard was launched by a select group of publishers, including Semafor, Pitchfork, Fast Company, Medium, LGBTQ Nation, Refinery 29, DIgiday, Polygon, SPIN, Kotaku, Frommer’s, The Verge, Smithsonian Magazine, Refinery 29, The Root, and more. Testing integration with your account. , ScienceAlert, AFAR Media, and more. Although many are news-focused, there are also several nonprofit organizations, including: News Literacy Project and education-focused news sites. 74, Among this debut list.

Image credits: flip board

“As we said earlier this year, we’re bringing ActivityPub to Flipboard and effectively reworking the entire backend to go with it,” Flipboard CEO Mike McCue said in a conversation with TechCrunch about the upcoming changes. explained. He said the company first integrated with his Mastodon at the API level, so users can log into their Mastodon accounts, see those posts from Flipboard, and interact with other users in the Fediverse. It is now possible. “But you had to have an account on all of these platforms,” McCue noted.

“What we’re announcing on Monday is essentially a roadmap for how to deploy ActivityPub and effectively tear down the walls of our own walled garden,” he said. added.

With this change, when a Flipboard user curates an article on the Flipboard app or posts it to one of our social magazines, with an optional comment, that “flip” (so-called “flip”) can be viewed on the new flipboard. com It will also appear as a post in your Mastodon account. . This is not the same server that his Flipboard previously set up (flipboard.social), which was a place to experiment with decentralized social media. Instead, the Flipboard app itself is now connected to fediverse. A user’s posts on Mastodon include links to both the article being flipped and the user’s Flipboard magazine, and the user’s profile shows her Flipboard profile page.

Image credits: flip board

Once this is rolled out, all Flipboard users will have one Flipboard.com account connected to fediverse, even if they host many Flipboard magazines. This is not ideal since their magazines may focus on different topics. But McCue believes Mastodon could one day support the concept of subfeeds, which would allow for further differentiation.

Users can opt out of having their “flips” posted to Mastodon, but being opted in is the default experience. The company plans to have all users’ accounts connected to Fediverse by the end of January. (This does not affect magazines that are set to “private” on Flipboard, which will remain private, he said.)

Flipboard currently has over 10,000 social magazine publishers on its app and over 250,000 individuals who use the Flipboard app to curate content. Considering today’s Mastodon, 1.5 million monthly active usersassuming Flipboard’s users don’t opt ​​out, this could be a notable change for the Fediverse when the Flipboard integration is fully rolled out.

Flipboard is just one of several companies currently embracing decentralized social media. In addition to X’s rival Instagram Threads, which began testing ActivityPub last week, other tech companies are moving in this direction as well. Automattic enables the federation of all blogs on WordPress.org and WordPress.com, and said it is working on doing the same for Tumblr next year. Medium and Mozilla have also set up their own servers, and the latter also supports his Mastodon client called Mammoth.

In Flipboard’s case, after integrating its backend with Fediverse, it may rethink what its frontend should look like for the new age of social media.

“The front end was built before federation,” McCue said. “What are the implications for federation on the front end? How are we thinking about curation and everything else and all the features and tools that we’ve created over the years? “How does it work in a federated world from a user experience perspective? That’s a great question,” he said.

Despite all the changes, Flipboard doesn’t need funding to support new development. As we move in this direction, we are depleting the profits of our own businesses.

The company is also betting on the fact that federated social media may be just the beginning of what’s to come across the web.

“Seeing what was happening with ActivityPub made it very clear that this is the future of the web,” McCue said. “The social web is people linking to pages and people linking to people. So it’s a more complex web.”

He sees Flipboard as part of that opportunity. “We need a way to do discovery and search that is beautiful, simple and easy to use. That’s what we’re focused on,” McCue added.

Source: techcrunch.com