Reviving Nostalgia: DNA Upgrade Leads to the Comeback of Cassette Tapes in 2025

DNA cassette tape technology

DNA Tapes: Revolutionizing Information Storage Beyond Standard Cassettes

Jiankai Li et al. 2025

In an innovative revival of 1960s technology, researchers have created a cassette tape that utilizes DNA for encoding information, substituting traditional iron oxide with synthetic DNA molecules printed onto plastic tape.

This groundbreaking technology boasts an astounding capacity for storing information. While conventional cassette tapes typically hold about 12 songs per side, DNA tapes can encapsulate every song ever recorded.

With a capacity of 10 megabytes per song, 100 meters of DNA cassette tape can accommodate over 3 billion songs. In total, the storage potential is a staggering 36 petabytes, equal to 36,000 terabytes of hard drive space.

Led by Jiang Xinyu and his team at Southern University of Science and Technology in Guangdong, China, these cassettes are engineered to represent digital data through the sequencing of DNA bases (A, T, C, G) much like binary code in computers. This enables the storage of various digital files, including text, images, audio, and video.

The researchers were thrilled by the public’s reaction following the announcement of the DNA cassette. New Scientist reported Jiang stating, “The diverse feedback we’ve received from scientists, artists, engineers, and educators has been rewarding, inspiring many to rethink the intersection of data, biology, and technology.”


The project team’s next objective is to create a specialized reading/writing mechanism for DNA cassettes that emulates the function of traditional magnetic tape drives. “Our new ‘head’ design will precisely align the DNA tape in a reaction chamber for chemical processes like reading and rewriting,” Jiang explains.

They anticipate that DNA cassette tapes could be available commercially within five years. “Our exploration of DNA cassette tape technology transcends mere storage capability; it encompasses a reimagining of how information exists in both physical and biological forms,” Jiang concludes.

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Source: www.newscientist.com

DNA Cassette Tapes: A Storage Solution for All Recorded Songs to Date

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DNA cassettes resemble music cassette tapes

Jiankai Li et al. 2025

With a modern twist, the nostalgic cassette tape may be resurging in the form of DNA. Previously used solely as a medium for information storage, researchers have now fused the concept with the style of 1980s cassette tapes, leading to the innovation termed DNA cassettes.

Xingyu Jiang and his colleagues at the Southern University of Science and Technology in Guangdong, China, crafted these cassettes by printing synthetic DNA molecules onto plastic tapes. “The sequences can be designed in such a manner that the order of DNA bases (A, T, C, G) conveys digital information just like binary code (0 or 1) in a computer,” he remarks. This allows for the storage of all forms of digital files, from text and images to audio and video.

A significant challenge of earlier DNA storage methods was accessing the data. To remedy this, the team implemented a series of barcodes on the tape to simplify searching. “It’s akin to locating a book in a library,” explains Jiang. “You first identify the shelf corresponding to the book and then locate the specific book on that shelf.”

The tape is also treated with a protective coating dubbed “crystal armor,” made from zeolite imidazolate, which ensures the integrity of the DNA. This allows the cassettes to retain data for centuries without degradation.

While classic cassette tapes can hold around 12 songs per side, the new 100-meter DNA cassette can house over 3 billion pieces of music comprising 10 megabytes of songs. This results in an astounding total data storage capacity of 36 petabytes, comparable to a 36,000 terabyte hard drive.

However, Jiankai Li warns that if one were to place the new tape into an old-school Walkman, it wouldn’t produce sound. “Our tapes contain DNA molecules,” he notes. “It’s similar to trying to play a photograph on a record player—the formats simply don’t align.”

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Source: www.newscientist.com