According to new research published in the journal Food, daily consumption of mango (Mangifera indica) over a period of 24 weeks has shown improvements in both short- and long-term glycemic control, reduced insulin resistance, increased insulin sensitivity, and favorable changes in body composition for pre-diabetic patients. These findings indicate that incorporating fresh mangoes into the diet may aid glycemic control for those at high risk for type 2 diabetes, offering a practical food-based strategy to enhance body composition.
Daily consumption of mangoes for 24 weeks significantly enhanced glycemic control, insulin sensitivity, and body composition in adults with diabetes, underscoring the potential of mangoes as an effective dietary strategy for metabolic health. Image credit: Mohan Nannapaneni.
Currently, over 130 million adults in the United States are living with diabetes or pre-diabetes, as reported by the CDC.
Predictions indicate that by 2030, nearly 40% of U.S. adults will be affected by prediabetes.
Early identification and prevention at the prediabetic stage is crucial, as many individuals remain unaware of their condition until complications arise.
Nutrition plays a vital role in glycemic control, and a balanced diet can promote both enhanced blood glucose regulation and overall long-term health.
In a diabetes prevention program, lifestyle interventions resulted in a 58% reduction in the incidence of type 2 diabetes, compared to a 31% reduction with metformin versus placebo. Thus, identifying accessible natural strategies to mitigate these risk factors is essential for delaying diabetes onset and minimizing associated complications.
Dietary practices enriched with fruits, vegetables, and bioactive compounds have shown beneficial effects on glycemic control and metabolic health.
Mangoes, being tropical fruits, are rich in several bioactive compounds such as carotenoids, ascorbic acid, dietary fiber, phenolic compounds, gallbladder acid, and quercetin.
“It’s not merely about the sugar content; the overall context of the food is crucial,” stated Dr. Raedeh Basiri, a Clinical Nutrition Researcher at George Mason University.
“This study stands as the first long-term clinical trial to showcase the metabolic and body composition benefits of mangoes for individuals with prediabetes.”
“Essentially, it’s about more than just the sugar present in food. The naturally occurring sugars in mangoes and other fruits are balanced by the fiber and other vitamins and nutrients that confer additional health advantages.”
“Foods with added sugars, like breakfast cereals and low-sugar snacks, often lack the same nutritional value and may even elevate the risk of diabetes.”
“The objective is to urge people to include whole fruits like mangoes in their dietary strategies for healthy eating and diabetes prevention.”
“Individuals at high risk for diabetes should emphasize not only the sugar content of their food but also how the sugar is delivered.”
Dr. Basiri and her team divided participants into two groups: one receiving fresh mangoes daily and the other receiving low-sugar granola bars.
Throughout the six-month study, researchers measured participants’ blood glucose levels, their insulin response, and body fat.
The results showed that the high-sugar content in mangoes (32 grams of sugar) was more beneficial than the low-sugar granola bars (11 grams of sugar).
The group consuming mangoes daily exhibited improved glycemic control, heightened insulin sensitivity, and reduced body fat.
“Our findings reinforce and broaden the emerging evidence on the metabolic advantages of consuming fresh mango daily among pre-diabetic individuals,” the researchers noted.
“Participants who ate an average of one mango each day for 24 weeks recorded lower fasting blood glucose levels compared to the control group.”
“Future studies should utilize objective dietary biomarkers (like plasma carotenoids and urinary polyphenols) to enhance accuracy and credibility.”
“Additionally, exploring the mechanisms underlying these observed effects, including the role of bioactive compounds in mango on insulin signaling and inflammation, is essential, especially across diverse populations.”
“Longer follow-up periods and comparisons with other fruits and dietary strategies could provide clarity on the specific benefits of mangoes for metabolic health.”
“Final investigations should delve into broader health advantages of mango consumption beyond glycemic control and body composition, including potential impacts on metabolic pathways and variations in gene expression, as individual responses to the same foods can differ.”
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Raedeh Basiri et al. 2025. Daily mango intake improves blood glucose and body composition outcomes in prediabetic adults: a randomized controlled study. Food 14 (17): 2971; doi: 10.3390/foods14172971
Source: www.sci.news
