Revolutionary Fully 3D Printed Microscope Set to Make Waves in 2025

3D Printed Microscope

Dr. Liam M. Rooney/University of Strathclyde

In early 2025, excitement surged within the research community with the release of a groundbreaking preprint paper detailing the world’s first fully 3D printed microscope. This innovative device was constructed in just hours and costs a fraction of traditional models.

Dr. Liam Rooney, a professor at the University of Glasgow, explained to New Scientist that the response to their revolutionary microscope has been overwhelming, attracting interest from biomedical researchers, community organizations, and even filmmakers. He stated, “The community response has been remarkable.” This significant research has been published in the Microscope Journal.

For the microscope’s body, the team employed designs from the Open Flexure project, a public resource for 3D printing scientific instruments. Utilizing a commercial camera and light source, they controlled the entire system using a Raspberry Pi computer.

The true innovation lies in the 3D-printed microscope lenses made from clear plastic, drastically reducing costs and enhancing accessibility. Traditional microscopes can cost thousands; in contrast, this new model can be assembled for less than £50.

“Since January, we have printed approximately 1,000 lenses in various shapes,” remarked team member Gail McConnell, from the University of Strathclyde.

Several companies producing commercial products that require optics have reached out to discuss potential collaborations, as affordable, lightweight 3D-printed lenses are still uncommon in large-scale production. The team has successfully used the microscope to analyze blood samples and tissue sections from mouse kidneys, validating its utility for medical and biological research.

The researchers aim to democratize access to microscopy, and they are making strides toward that goal. Collaboration with a lab at the Kwame Nkrumah University of Science and Technology in Ghana is underway to enhance microscope accessibility for researchers and students across West Africa. Additionally, they’ve secured funding from the UK Institute for Technology Strategy, and are involved in programs designed to upskill and empower students facing educational barriers.

Furthermore, the team has developed a new microscope course through the Strathclyde Light Microscopy Course, aimed at researchers of all experience levels and providing a unique educational opportunity in the UK. Rooney noted, “This is revolutionizing our teaching methods.”

Looking towards the future, there is substantial potential for further enhancements in 3D printed microscopes. The research team is working to improve resolution without raising costs and have found methods to enhance image contrast by 67%.

McConnell emphasized that the microscope’s design leverages consumer electronics and accessible 3D printing technologies, stating that the future advancements and capabilities are limited only by current 3D printing technology. “As these printers advance, so will our capabilities. The only bottleneck is technology, not creativity,” she explained. “We’re frequently contacted by individuals eager to see new designs.”

Source: www.newscientist.com

Revolutionary Fully 3D Printed Microscope Set to Launch in 2025

3D Printed Microscope

3D Printed Microscope

Dr. Liam M. Rooney/University of Strathclyde

In early 2025, a groundbreaking paper revealed the world’s first fully 3D printed microscope, sparking significant enthusiasm among researchers. This innovative microscope can be constructed in just a few hours and costs significantly less than traditional models.

Dr. Liam Rooney, a professor at the University of Glasgow involved in this project, stated to New Scientist that coverage of the microscope has prompted outreach from biomedical researchers, community organizations, and filmmakers worldwide. “The community response has been amazing,” he noted. The research has been subsequently published in Microscope Journal.

His team utilized the OpenFlexure design, a publicly available resource for creating scientific instruments via 3D printing. Additionally, they incorporated a commercially available camera and light source, all controlled by a Raspberry Pi computer.

A major breakthrough was the 3D printing of microscope lenses using clear plastic, significantly reducing costs and making microscopy more accessible. While traditional microscopes can cost thousands, this new version is available for under £50.

Since January, the team has produced approximately 1,000 lenses in various shapes, according to Gail McConnell from the University of Strathclyde, UK.

Several companies manufacturing products requiring lenses have shown interest in the team’s research, as inexpensive, lightweight 3D-printed lenses are rare in large-scale production. They tested the microscope on blood samples and thin sections of mouse kidneys, confirming its potential utility in medical and biological research.

The team’s mission is to democratize access to microscopy. They are collaborating with the Kwame Nkrumah University of Science and Technology in Ghana, aiming to enhance microscope accessibility for researchers and students in West Africa. They have also secured funding from the UK Institute for Technology Strategy and participate in initiatives that empower students facing educational barriers.

In addition, they have developed a new microscope course at the Strathclyde Light Microscopy Course, tailored for researchers of all experience levels. Mr. Rooney emphasized, “This is truly changing how we educate.”

Furthermore, researchers believe there’s ample opportunity for improvement. They are focused on enhancing resolution without adding costs, having already improved contrast by up to 67%.

McConnell remarked that because the microscope is designed for low-cost consumer electronics and accessible 3D printers, its future scalability is tied to advancements in 3D printing technology. “As these printers improve, so will we. The bottleneck isn’t imagination,” she explained. “We are continually receiving inquiries to develop new innovations.”

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Source: www.newscientist.com

Water-Soluble 3D Printed Electronics for Fast Recycling

Prototype electronics can be made from polymers that dissolve in water, facilitating recycling.

ZEYU YAN/University of Maryland

Devices like Bluetooth speakers can be 3D printed using water-soluble materials in just a few hours. This innovation enables rapid prototyping, easier recycling of electronic waste, and encourages more sustainable manufacturing practices for consumer electronics.

Researchers have successfully created technology that can dissolve, including printed circuit boards that house essential components and wiring for modern electronics. Each year, hundreds of millions of printed circuit boards are produced for military aircraft, automobiles, medical devices, smartphones, and inexpensive toys. Yet, globally, only a fraction of these devices are recycled through labor-intensive methods, often involving shredding to reclaim usable materials, according to Huaishu Peng from the University of Maryland.

Peng and his team crafted a 3D printed circuit board with polyvinyl alcohol, a polymer that dissolves in water. They filled the circuit board’s channels with liquid gallium-indium metal alloys for wiring, and manually attached electronic components. After sealing the circuit with a polymer adhesive, the device was dried for an hour at 60 °C.

This method enabled researchers to assemble functioning prototypes of a Bluetooth speaker, a fidget toy, and an electronic gripper with three fingers. A small amount of water does not immediately damage these devices, but after soaking for 36 hours at a room temperature of 22°C, they dissolve.

The researchers could then easily retrieve most electronic components and liquid metals, which accumulated as small beads. The evaporation of water also allowed them to recover 99% of the dissolved polyvinyl alcohol.

Soluble circuit boards are particularly beneficial for designers who aim to quickly test and validate electronic prototypes, as recycling traditional printed circuit boards presents significant challenges. As noted by Jasmine Lu from the University of Chicago, Illinois, in her study on circuit board reuse, “Printed circuit boards are a major source of e-waste during the prototyping of electronic devices.”

A 2022 United Nations Report regarding e-waste revealed that Asia generated 600,000 tons of discarded circuit boards but managed to recycle only 17%. In contrast, Europe and North America produced 300,000 tons of printed circuit boards, achieving a recycling rate of 61% in Europe and 44% in North America.

What sets this approach apart is that virtually anyone with a 3D printer can implement this dissolvable electronics methodology, making it more accessible compared to other sustainable electronics initiatives, according to Lu. For practical use, Peng suggests that the devices can be safeguarded with a temporary waterproof casing.

Nonetheless, due to the inherent fragility of these circuit boards, Lu indicates that soluble electronics are currently more suited for rapid prototyping rather than mass production of finished electronic goods.

Peng and his colleagues have not dismissed the idea of mass production. They are reaching out to circuit board manufacturers to explore the possibilities. For now, Peng aims to utilize this technology to enable university students to rapidly prototype and reuse designs.

“Typically, you would need to outsource circuit board production to a factory, which could take weeks for manufacturing and shipping,” he explains. “You can design something here, print it in under 30 minutes, and if it doesn’t work, simply dissolve it in water and try again.”

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Source: www.newscientist.com

World’s First 3D Printed Trachea Successfully Implanted in Woman

In a groundbreaking achievement in the field of medicine, a 3D printed organ has been successfully transplanted into a patient for the first time in history. A South Korean patient is currently recovering with a new trachea partially made from someone else’s stem cells.

The pioneering 3D-printed trachea transplant took place at Seoul St. Mary’s Hospital in 2023, led by a team of scientists, doctors, and engineers. The recipient was a woman in her 50s who had lost part of her trachea following thyroid cancer surgery.

While 3D printed bones and food have shown some success, the transplantation of organs marks a new frontier in medical technology.

What is the 3D printed trachea made of?

The patient’s new trachea is composed of cartilage and mucosal lining, sourced from nasal stem cells and chondrocytes obtained from other patients. The bioink used also contains polycaprolactone (PCL) for structural support, different from the standard ink used in home printers.

Given its biodegradable nature, PCL has a limited lifespan of about 5 years. However, researchers hope that within this timeframe, the artificial organ will stimulate the patient’s body to regenerate its own windpipe.

According to the hospital, traditional treatments post-tracheal resection do not allow for restoration of the original organ and can be complex and risky. The introduction of 3D printed organs could transform the treatment of patients with thyroid cancer, congenital defects, and tracheal trauma.

Significantly, patients undergoing this procedure did not require immunosuppressants. At the six-month mark post-surgery, the patient’s trachea was healing well with the development of new blood vessels.

The research is currently undergoing peer review for publication in a scientific journal.

How do I 3D print a trachea?

The dimensions of the trachea must be customized for each patient based on their CT and MRI data. In this particular case, the trachea’s length needed to be under 5 cm (2 inches).

The printing process took less than two weeks, and the implantation occurred during a half-day surgery.


The successful collaboration behind this procedure involved the Catholic University of Korea, Gachon University, and T&R Biofab, the biomedical engineering company responsible for manufacturing the printer.

This achievement is the culmination of two decades of research, dating back to 2004 with preliminary laboratory studies on animals such as beagles. T&R Biofab’s specially designed printer enabled the creation of personalized, hollow, tubular organs with high precision technology.

Although the printer was tailored for Seoul St. Mary’s Hospital, there is potential for future expansion beyond this specific institution.

Dr. Paulo Marinho, Head of Science Strategy at T&R Biofab, expressed optimism about the future of 3D bioprinting technology and its potential to address organ shortages for transplantation.

About our experts

Dr. Paulo Marinho, with a background in chemical engineering and postdoctoral experience in regenerative medicine, plays a crucial role at T&R Biofab in advancing the frontiers of 3D bioprinting.

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Source: www.sciencefocus.com

Artificial Intelligence creates personalized 3D printed prosthetic eyes

A man with artificial eyes not made by AI

Stephen Bell, Ocupeye Ltd.

Prosthetic eyes designed with artificial intelligence and 3D printing could benefit more people by requiring 80% less time for human experts compared to traditional manufacturing methods. Small trials also suggest that this approach leads to adequate prostheses in most cases.

For example, in the UK, Approximately 1 in 1,000 people wears a prosthetic eye., it takes a highly trained ophthalmologist to take an impression of the eye socket. Many people wearing such prostheses also have orbital implants that replace lost eye volume and create a surface to which muscles can be reattached, allowing natural eye movement. Masu. A prosthesis is placed over this to give it a natural appearance.

The standard process for making a prosthetic limb takes about eight hours; Johan Reinhardt Researchers at the Fraunhofer Institute for Computer Graphics in Darmstadt, Germany, have developed a method to automatically design and 3D print an implant that fits into a wearer's eye socket and aesthetically matches the remaining eye. .

“It's more comfortable to do an optical scan than to have someone pour this alginate.” [mould-making material] It seems difficult to make an impression on the eye socket, especially for children. [sit through] This is the procedure,” Reinhardt said.

In the new process, an optical coherence tomography scanner uses light to create a 3D model of a person's missing eye, so the back of the prosthesis can be designed to fit snugly. A color image of the remaining eye is also taken to ensure an aesthetic match.

The data is collected into an AI model, a design is created, and then 3D printed on a machine that can operate at a resolution of 18 billion droplets per cubic centimeter.

Once the prosthesis is printed, a human eye doctor can polish and adjust it for the perfect fit. This task takes only 20% of the time of the existing process.

3D printed prosthetic eye designed by AI

Johann Reinhardt, Fraunhofer IGD

In a trial of 10 people at Moorfields Eye Hospital in London, only two people found these prostheses did not fit properly. Neither has orbital implants, which Reinhardt says poses problems for scanners and AI designers.

The team hopes to improve the process to significantly reduce the cost required to create convincing prosthetics and make them available to more people. However, Reinhardt says it is unlikely that future prosthetics will be created without human experts.

“We think of this like a tool for ophthalmologists,” he says. “So this is not going to replace an eye doctor, but it's a new process that they can use, and we think it's going to give them better results in terms of appearance.”

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Source: www.newscientist.com

‘Spanish Tech Startup Aims to Introduce 3D Printed Meat to Our Tables’

Cocuus, a cutting-edge technology start-up headquartered in an industrial park on the outskirts of Pamplona, ​​takes on a group of drunken tourists who willingly surrender to the sound of fate, horns and hooves during a bull run in a Spanish city. They are just as happy to embrace every bit of the clichés of their sector. A festival held every July.

Table soccer? check.lager and IPA on tap? check. Inspirational Message – Preferably an homage to Alice in Wonderland with “Before Breakfast She Believes in Six Impossible Things”? Check. How about sci-fi memorabilia, perhaps Tintin's moon rocket or Alien's xenomorph head? Check. clearly.

A clue as to what's different lies in the platters of oysters, tuna, foie gras, bacon, nuggets, steak and charcuterie displayed at the bar. Nothing is what it seems. Steak and pork do contain meat, but like other dishes, they are the result of years of research into “copycat foods,” culminating in the rapid burst of 3D printing.

Founded six years ago by Patxi Larumbe and Daniel Rico, Cocuus continues its loud and disruptive quest to fuse science, technology, and nutrition. It announced its existence three years ago when the duo decided to attract meat lovers in Pamplona and beyond by 3D printing steaks and posting them on social media.




Patsi Larumbe with 3D machinery to produce shrimp. Photo: Markel Redondo/Guardian

“I knew that if I was going to print something, it had to be something that would piss people off,” says Larumbe, who quit a €100,000-a-year job in construction materials to focus on the startup.

“We knew that printing a big steak would upset a lot of people in Spain, especially in northern Spain. So we printed the steak and posted it on Facebook, Twitter, and LinkedIn. 700,000 people. We got replies. Most of them were people telling us to shove it up our butts. It was crazy and I was really happy.”

Even better, the product also attracted the attention of American food company Cargill, which is now one of Coccus' major investors. This Spanish company also specializes in formulations and machinery used in food printing, and for the past few years has designed and manufactured multi-nozzle printers that can create food products that mimic the taste and texture of meat and fish. . The hardware can also be painted on molded purees to look like a plate of chicken and chips or hake and peas, creating meals that stimulate the eyes and appetites of people with swallowing difficulties.

As befits a self-confessed bunch of sci-fi geeks, much of the inspiration comes from the transport plane that beams the crew of the USS Enterprise between the ship and the planet's surface. Larrambe said Social Media Steak is the result of experimenting with the idea of ​​converting steak cells into data that can be teleported. After taking X-rays and cross-sectional scans of real steaks, they located the cells that make up the meat, fat, and bones, converted them into data, and entered them into a printer.




Larumbe cooks 3D vegan steaks. Photo: Markel Redondo/Guardian

“We're a group of physicists, geometry mathematicians, geeks, and Star Trek and Star Wars enthusiasts who are starting to research food,” Larumbe says. “Every food company studies things in very similar ways, using nutritionists and food technologists, and they come to very similar conclusions to existing ones. To come up with new cakes. If you get a bunch of bakers together, they'll come up with something very similar to what already exists and what we know as cake.”

But if you combine a physicist with a nutritionist, a machine maker, a baker and a comedian, he added, “you'll create a new kind of cake.”

Cocuus' bacon and foie gras are made from a rich vegetable paste, while the steaks are made with real beef from 50kg of meat that would otherwise be discarded or made into cat food when cows are slaughtered. The fat in steak marbling is made from a vegetable mixture and is much lower in saturated fat than the real thing.

Mr Larumbe exudes confidence in his products as surely as his printers extrude meat and vegetable pastes, but he also takes a swipe at many of his supposed rivals and says they've made light work of the vegan burger boom in recent years. He dismissed it as a “bubble” and pointed out the huge costs and low costs. Yields of lab-grown meat.




Cocuus' 3D printed meat steaks contain real beef. Photo: Markel Redondo/Guardian

When asked what sets his company apart in an already crowded field, he insists it's scale. Cocuus and its partner Foody's have sold 80,000 pieces of meat-free foie gras and 200,000 pieces of cholesterol-free vegan bacon since the products hit Carrefour store shelves last September. Cocius also has the production capacity to produce 1,000 tons of bacon and his 3,000 tons of foie gras annually at his factory in the city of Tudela.

“We are the first company in the world to successfully do this on an industrial scale rather than on an experimental scale,” says Larumbe.

“Secondly, our imitation is complete and has never existed before. There was a vegetarian version, but the content was bad. Thirdly, there is something fundamentally wrong here. We have scientists coming up with different formulations and technologies. All of this means we are the most advanced company in the world in this field, and one that partners with the largest international food companies. about it.”

What has the local reaction been like in areas where beef is highly revered?

Making bacon without pigs or “seeing a bunch of idiots make steaks with 3D printing” may not be appealing to Navarre's farmers, Larumbe admits. But after learning more about the company and understanding that more money could be made for the cows thanks to new technology that utilizes parts that were traditionally thrown or fed to cats, many He says people are coming.

Once again, after spending an hour or two with him, you get the impression that Larumbe doesn't really care about other people's opinions.

“Humanity progresses because of people who disagree,” he says. “There is no progress if you and I agree. We don't agree on everything.”

Source: www.theguardian.com

3D Printed Ice Blood Vessels Could Enhance the Quality of Artificial Organs

3D printed blood vessel ice template

Philip LeDuc and others/Carnegie Mellon University

Complex artificial organs can be created by 3D printing molds of veins, arteries, and capillaries in ice, casting them in organic materials, and melting the ice to form delicate, hollow networks. This leaves space for the complex vascular grafts required for the development of laboratory-cultured internal organs.

Researchers have been working for decades to develop artificial organs to meet the high global demand for transplants such as hearts, kidneys and livers. However, creating the vascular network necessary to keep them alive remains a challenge.

Existing technology can grow artificial skin and ears, but the meat and organ materials disappear when they are more than 200 micrometers away from blood vessels. Philippe Leduc at Carnegie Mellon University in Pennsylvania.

“It's about twice the width of a hair. Once you get through that, and you can't access nutrients anymore, your cells start dying,” he says. Therefore, new processes will be needed to produce internal organs cheaply and quickly.

LeDuc and his colleagues experimented with printing blood vessels with meltable wax, which requires fairly high temperatures and can leave behind residue. “One day, out of the blue, a student of mine said, 'What if we tried using water, the most biologically compatible substance in the world?'” he says. “And I'm like, 'Oh, yeah.' It still makes me laugh. It's that simple.”

They developed a technique that uses a 3D printer to create a mold of the inside of an organ's blood vessels in ice. In the test, they embedded them in a gelatin material that hardens when exposed to ultraviolet light before the ice melts away.

The researchers used a platform cooled to -35°C and a printer nozzle that ejected hundreds of drops of water per second, allowing them to print structures as small as 50 micrometers in diameter.

LeDuc says the process is conceptually simple, but requires complete coordination. If the droplet is ejected too quickly, the droplet will not solidify quickly enough to create the desired shape, but if it prints too slowly, it will just form a clump.

The system is also affected by weather and humidity, so researchers are looking into using artificial intelligence to adjust the printer to different conditions.

They also used a version of water in which all the hydrogen was replaced with deuterium, a stable isotope of the element. This so-called heavy water has a high freezing point and helps create a smooth structure by avoiding unwanted crystallization. Deuterium is not radioactive, unlike some isotopes, and tests have shown it to be safe for creating artificial organs, LeDuc said.

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Source: www.newscientist.com