Scientists Unlock the Genome of Sweet Potatoes

Researchers have successfully created a chromosomal-level genomic assembly of a sweet potato cultivar known as “Tanzania.”



“Tanzania” sweet potato variety. Image credit: Benard Yada from the National Crop Resources Institute in Uganda.

The sweet potato is a crucial global staple crop that supports millions of people, particularly in sub-Saharan Africa. Its inherent resilience to harsh climates significantly contributes to food security.

Despite its importance, this humble root vegetable has hidden its genetic complexities for many years.

Sweet potato DNA is exceptionally intricate. While humans have two sets of chromosomes from each parent, sweet potatoes possess six sets.

This phenomenon, known as Hexaploidy, involves deciphering genetic codes that aim to piece together a set of six distinct, albeit similar, encyclopedias mixed together.

Utilizing advanced DNA sequencing and other state-of-the-art technologies, Professor Zhangjun Fei and his team at the Boyce Thompson Institute have produced the first complete genetic blueprint of “Tanzania,” which is widely appreciated in Africa for its stress tolerance and high dry matter content.

The key challenge was organizing the 90 chromosomes of the plant into six original sets known as haplotypes.

The researchers succeeded in either completely or incrementally separating this intricate genetic puzzle.

“Having this complete gradual genome provides an unprecedented level of clarity,” Professor Fei noted.

“This allows us to explore remarkable details of the sweet potato’s genetic narrative.”

The research team found that the sweet potato genome is a mosaic formed from various wild ancestors, some of which remain unidentified.

Approximately one-third of the genome is derived from ipomoea aequatoriensis, a wild species from Ecuador believed to be a direct progenitor of sweet potato cells.

Another significant portion is similar to the wild species of Central America, Ipomoea batatas 4x, though actual wild donors have yet to be discovered.

Dr. Shan Wu, a researcher at the Boyce Thompson Institute, stated:

“In sweet potatoes, ancestral sequences are intermixed within the same chromosome, resulting in a unique genomic structure.”

This complex genetic heritage suggests that sweet potatoes can be tentatively classified as segmented allopolyploids—hybrids that effectively function as though derived from a single species while originating from different ones.

This genomic merging and recombination grant sweet potatoes exceptional adaptability and disease resistance, essential for subsistence farmers globally.

“The six sets of chromosomes in sweet potatoes also contribute to their resilience,” Professor Fei added.

“With multiple versions of key genes, these plants can retain backup copies that assist them in surviving droughts, resisting pests, and adapting to diverse environments. This phenomenon is referred to as the polyploid buffer.”

“However, to fully comprehend the genetic capabilities of sweet potatoes, we need to decode multiple varieties from various regions, as each can possess unique genetic traits absent in others.”

Survey results were published this month in the journal Nature Plants.

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S. Woo et al. Gradual chromosomal level assembly provides insight into the genomic architecture of hexaploid sweet potatoes. Nature Plants Published online August 8, 2025. doi:10.1038/s41477-025-02079-6

Source: www.sci.news

The strength of your sweet tooth could be linked to your sugar-digesting capabilities

When it comes to food cravings, some of us lean towards ice cream while others prefer something savory. It can be hard to understand how people have different tastes when it comes to food. How can anyone not enjoy chocolate?

A recent study may provide some answers. It appears that individuals who have an aversion to sweet foods may have a genetic anomaly in their DNA that makes it challenging for them to digest sucrose (sugar).



Genetic issues with sucrose digestion are commonly linked to irritable bowel syndrome. However, a new study featured in the journal Gastroenterology suggests that defects in the sucrase-isomaltase (SI) gene could also impact how much we enjoy sweet treats.

To investigate further, a team of researchers from the University of Nottingham conducted studies on mice lacking the SI gene. They discovered that these mice had a decreased preference for sucrose consumption.

The researchers then expanded their study to include humans, analyzing data from 6,000 individuals in Greenland and approximately 135,000 individuals in the UK from the UK Biobank. Their findings showed that Greenlandic participants with a completely non-functional SI gene consumed more sugar compared to those with a functioning gene. This pattern was also observed in the UK, where individuals with a partially functioning SI gene showed a lower inclination towards sweet foods.

If you are not a fan of sweet treats, could it be due to a genetic issue? Not necessarily.

“If you have a dislike for sweet foods, it may be linked to reduced SI function, but other factors with bigger impacts are likely contributing to your preference for less sweet foods,” said Dr. Mette Andersen, a co-author of the study and assistant professor at the University of Copenhagen in Denmark, as reported by BBC Science Focus.

Excessive sugar consumption is a significant factor in the rise of obesity and type 2 diabetes. Researchers involved in the study believe that targeting the SI gene with new medications to enhance digestive health could potentially help reduce sugar intake.


About our experts

Dr. Mette Andersen is an assistant professor at the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen, Denmark.

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Source: www.sciencefocus.com

Sweet Dreams Universe: Exploring the Mind of a Psychic Infant | Activities

HHow do you follow up on a game that made the world cry? It’s a question that’s vexed writer Graham Parks since his 2021 BAFTA-winning Before Your Eyes. Released during the height of lockdown, Parks’ webcam-controlled story uses the player’s blinks to fast-forward through protagonist Benny’s memories, blinking through each uplifting and heartbreaking moment of his existence. It quickly gained a reputation as Twitch’s tearjerker, its moving story and the misery of the pandemic’s last few months creating a perfect, tissue-paper-shredding storm. “As a writer, it was definitely a scary thing,” Parks says. “I’m interested in using games to tell concise, emotional stories, but I can’t say they’re going to make you cry every time.”

Still, tears or no tears, things are already looking pretty promising for Goodnight Universe, an intriguing sequel to Before Your Eyes. Developed by Nice Dream, an all-new studio founded by creators Graham Parks and Oliver Lewin, Goodnight Universe has already won the 2024 Game of the Year award at the TriBeCa Film Festival, beating out the excellent Thank Goodness You’re Here!

So moving…Goodnight universe Photo: Nice Dream

What’s the premise of Goodnight Universe? “It’s a game where you play as a baby with psychic powers,” Parks says with a coy laugh. Using a webcam or a VR headset, players step inside the tiny body of baby Isaac, who begins to develop mysterious abilities. The slithering psychic must grasp his rapidly blossoming new powers and use his eyes to bend the vast world around him to his will – preferably without scaring Isaac’s poor parents, Parker explains.

“Before Your Eyes was a game about disempowering the player,” Parks says, “but we always felt that mechanics like blinking and eye tracking could also be used to empower the player and give them a sense of magic.”

Second grade angst…Goodnight universe. Photo: Nice Dream

Sounding more like Boss Baby than indie darling, Goodnight Universe’s storyline was definitely a tonal shift, and one that took the team a while to realise. “We had been anxious about the second album for a really long time,” Parks says. “We even had to make a rule in ideation sessions that we couldn’t even talk about ‘Before Your Eyes’.”

Luckily, inspiration struck from a new face in the room. “Our lead designer, Bella, had just had her first child,” says Parks. “She started coming into meetings and was at an age where you’d sit down and she’d just stare at one thing for an hour and you’d forget she was there. We’d become known as people who make games that don’t move around a lot… I noticed her quietly staring at me, and that was my ‘Oh, noooo!’ moment.” Goodnight Universe was born.

From kinetically changing TV channels to sending wooden blocks flying, Goodnight Universe takes players on Isaac’s strange but heartwarming journey to understand his powers, be accepted by his family, and avoid being kidnapped by a shady tech company. The diaper-clad protagonist is voiced by Top Gun Maverick’s Lewis Pullman, and the supporting cast includes actors from TV shows like Veep, Barry, and The Daily Show, and the LA studio cleverly takes advantage of its proximity to Hollywood.

“Many indies [the union] “Some actors only do film or TV,” adds the game’s director and composer Oliver Lewin, “but the truth is, these actors are really excited about this.”

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Thanks to its BAFTA win, Before Your Eyes has transcended its webcam origins, making its way to PlayStation VR2 and joining Netflix’s steadily growing library of mobile games. But while you can play Goodnight Universe in VR and turn off face tracking, for Lewin, the game’s story is still tied to the humble webcam. “For us, the face-tracking technology is there to enhance immersion,” Lewin says. [few] Developers are researching this…There’s a lot you can do with just a simple webcam, and everyone has one.”

“Our game is, in many ways, a playable movie,” Parks adds. “I think what motivates us more than any exciting controls is how we can use this medium to tell a story in an interesting and unique way.”

In a medium that revolves around slaying dragons, crushing demons and embarking on intergalactic power fantasies, there’s something fresh and quaint about Goodnight Universe, but after shedding a fair few tears over Before Your Eyes, if anyone can do justice to this strange premise, it’s the quirky LA Art Games collective.

Goodnight Universe is scheduled for release on PC in 2025. Other platforms are yet to be determined.

Source: www.theguardian.com