Breast Milk Defends Against Infections Threatening Pregnancy

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Streptococcus Bacteria are responsible for vaginal and urinary tract infections, as well as neonatal infections

Cavallini James/BSIP/Universal Images Group via Getty Images

The sugars found in breast milk play a significant role in combating common strains of Streptococcus Bacteria, which can cause complications during pregnancy if they infect the vagina.

Research on breast milk remains ongoing. “This is the second most crucial liquid in the universe after water, and yet its intricacies remain largely unexplored,” states Stephen Townsend from Vanderbilt University in Tennessee.

Investigators are starting to uncover the beneficial sugar structures unique to breast milk: human milk oligosaccharides (HMOs). While once regarded as trivial sugars, they are now believed to function as effective prebiotics.

Prior investigations into HMOs primarily focused on their advantages for gut microbiota. However, Townsend and his team shifted their attention to their impact on vaginal health, specifically how HMOs may assist in regulating the balance of beneficial bacteria while managing potentially harmful Group B Streptococcus (GBS).

“Group B Strep is a bacterium we all harbor,” Townsend notes. “It typically poses no harm, remaining undetected in most cases.” Nevertheless, GBS can lead to serious illnesses in immunocompromised individuals, including pregnant women and newborns, causing various complications such as preterm births. Thus, women with vaginal GBS infections are often prescribed antibiotics during pregnancy.

Townsend and his team monitored GBS and the growth of lactobacillus Bacteria when exposed to HMOs, conducting their research in three distinct scenarios: live mice and lab-created vaginal tissue. Across all three settings, HMOs were found to enhance beneficial bacterial growth while inhibiting GBS.

As a result, Townsend suggests the presence of a “small storm of positive effects.” He elaborates that GBS struggles to thrive in an HMO-rich environment, while healthy bacteria not only consume HMOs for nourishment but also multiply and flourish, further hampering GBS growth. Additionally, the metabolism of HMOs by beneficial bacteria leads to a more acidic environment and the generation of fatty acids that can kill more harmful bacteria.

This discovery opens pathways for regulating and restoring a healthy vaginal microbiome. “These insights present new tools and strategies of significant therapeutic value for women and their infants,” remarks Katie Patras from Baylor College of Medicine, Texas. However, she emphasizes that potential treatments are still in developmental stages.

Even if new therapies emerge, researchers maintain that the most effective strategy for treating GBS infections remains the use of antibiotics. “Our work is not intended to replace antibiotics,” insists Townsend. “Our research aims to preserve their efficacy.” This is crucial, considering that overuse of antibiotics can contribute to the issue of antibiotic resistance. Innovative therapies like HMOs to modulate microbiomes may ultimately reduce the volume of antibiotics required to combat GBS.

“These synergistic interactions can prove extremely beneficial,” he asserts. Lars Bode from the University of California, San Diego, cautions that the application of breast milk therapies should wait until further research validates their efficacy, as unprocessed milk may pose additional risks, including infections like HIV.

In the interim, Townsend aims to deepen understanding of the unique evolutionary adaptations humans have developed in their HMOs.

“It’s incredibly daunting that we have barely scratched the surface in recognizing the strength of breast milk,” Bode expresses.

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Source: www.newscientist.com

Unveiling the Hidden Dangers Threatening the Internet’s Vital Network of Cables

ITonga was plunged into darkness in the aftermath of a massive volcanic eruption in the early days of 2022. The undersea eruption, 1,000 times more powerful than the Hiroshima bomb, sent tsunamis into Tonga’s neighbouring islands and covered the islands’ white coral sand in ash.

The force of the eruption of the Hunga Tonga Hunga Ha’apai volcano cut off internet connections to Tonga, cutting off communications at the very moment the crisis began.

The scale of the disruption was clear when the undersea cables that carry the country’s internet were restored weeks later. The loss of connectivity hampered restoration efforts and dealt a devastating blow to businesses and local finances that rely on remittances from overseas.

The disaster has exposed extreme vulnerabilities in the infrastructure that underpins how the Internet works.

Nicole Starosielski, a professor at the University of California, Berkeley and author of “The Undersea Network,” says modern life is inseparable from the running internet.

In that sense, it’s a lot like drinking water: a utility that underpins our very existence, and like water, few people understand what it takes to get it from distant reservoirs to our kitchen taps.

Modern consumers have come to imagine the internet as something invisible floating in the atmosphere, an invisible “cloud” that rains data down on our heads. Many believe everything is wireless because our devices aren’t connected by cables, but the reality is far more unusual, Starosielski says.


An undersea internet cable laid on the ocean floor. Photo: Mint Images/Getty Images/Mint Images RF

Nearly all internet traffic — Zoom calls, streaming movies, emails, social media feeds — reaches us through high-speed fibre optics laid beneath the ocean. These are the veins of the modern world, stretching for around 1.5 million kilometres beneath the surface of the ocean, connecting countries through physical cables that conduct the internet.

Speaking on WhatsApp, Starosielski explains that the data transmitting her voice is sent from her phone to a nearby cell tower. “That’s basically the only radio hop in the entire system,” she says.

It travels underground at the speed of light from a mobile phone tower via fibre optic cable on land, then to a cable landing station (usually near water), then down to the ocean floor and finally to the cable landing station in Australia, where The Guardian spoke to Starosielski.

“Our voices are literally at the bottom of the ocean,” she says.

Spies, Sabotage, and Sharks

The fact that data powering financial, government and some military communications travels through cables little thicker than a hose and barely protected by the ocean water above it has become a source of concern for lawmakers around the world in recent years.

In 2017, NATO officials reported that Russian submarines were stepping up surveillance of internet cables in the North Atlantic, and in 2018 the Trump administration imposed sanctions on Russian companies that allegedly provided “underwater capabilities” to Moscow for the purpose of monitoring undersea networks.

At the time, Jim Langevin, a member of the House Armed Services Committee, said a Russian attack on the undersea cables would cause “significant harm to our economy and daily life.”


Workers install the 2Africa submarine cable on the beach in Amanzimtoti, South Africa, in 2023. Photo: Logan Ward/Reuters

Targeting internet cables has long been a weapon in Russia’s hybrid warfare arsenal: When Russia annexed Crimea in 2014, Moscow cut off the main cable connection to the peninsula, seizing control of the internet infrastructure and allowing the Kremlin to spread disinformation.

Global conflicts have also proven to wreak unexpected havoc on internet cable systems: In February, Iran-backed Houthi militants attacked a cargo ship in the Red Sea. The sinking of the Rubimaa likely cut three undersea cables in the region, disrupting much of the internet traffic between Asia and Europe.

The United States and its allies have expressed serious concerns that adversaries could eavesdrop on undersea cables to obtain “personal information, data, and communications.” A 2022 Congressional report highlighted the growing likelihood that Russia or China could gain access to undersea cable systems.

It’s an espionage technique the US knows all too well: in 2013, The Guardian revealed how Britain’s Government Communications Headquarters (GCHQ) had hacked into internet cable networks to access vast troves of communications between innocent people and suspected targets. This information was then passed on to the NSA.

Documents released by whistleblower Edward Snowden also show that undersea cables connecting Australia and New Zealand to the US were tapped, giving the NSA access to internet data in Australia and New Zealand.

Despite the numerous dangers and loud warnings from Western governments, there have been few calls for more to be done to secure cable networks, and many believe the threat is exaggerated.

The 2022 EU report said there were “no published and verified reports suggesting a deliberate attack on cable networks by any actor, including Russia, China or non-state groups.”

“Perhaps this suggests that the threat scenarios being discussed may be exaggerated.”

One expert speaking to the Guardian offered a more blunt assessment, describing the threat of sabotage as “nonsense”.


TeleGeography map of undersea internet cables connecting the US, UK and Europe. Photo: TeleGeography/https://www.submarinecablemap.com/

The data bears this out, showing that sharks, anchors and fishing pose a bigger threat to the global Internet infrastructure than Russian espionage. A US report on the issue said the main threat to networks is “accidental human-involved accidents.” On average, a cable is cut “every three days.”

“In 2017, a vessel accidentally cut an undersea communications cable off the coast of Somalia, causing a three-week internet outage and costing the country $10 million per day,” the report said.

An Unequal Internet

But for many experts, the biggest risk to the internet isn’t sabotage, espionage or even rogue anchors, but the uneven spread of the globe-spanning cable infrastructure that ties together the world’s digital networks.

“There aren’t cables everywhere,” Starosielski said. “The North Atlantic has a high concentration of cables connecting the U.S. and Europe, but the South Atlantic doesn’t have as many.”

“So you’re seeing diversity in terms of some parts of the world being more connected and having multiple routes in case of a disconnection.”

As of 2023, there are more than 500 communication cables on the ocean floor. Map of the world’s submarine cable networks These are found to be mainly concentrated in economic and population centres.

South Pacific Submarine Cable Network

Map of undersea internet cables in the South Pacific.

The uneven distribution of cables is most pronounced in the Pacific, where a territory like Guam, with a population of just 170,000 and home to a U.S. naval base, has more than 10 internet cables connecting the island, compared with seven in New Zealand and just one in Tonga, both with a population of more than 5 million.

The aftermath of the 2022 Tonga eruption spurred governments around the world to act, commissioning reports on the vulnerabilities of existing undersea cable networks while technology companies worked to harden networks to prevent a similar event from happening again.

Last month, Tonga’s internet went down again.

Damage to undersea internet cables connecting the island’s networks caused power outages across much of the country and disruption to local businesses.

For now, economic fundamentals favor laying cables to Western countries and emerging markets where digital demand is surging. Despite warnings of sabotage and accidental damage, without market imperatives to build more resilient networks, there is a real risk that places like Tonga will continue to be cut off, threatening the very promise of digital fairness that the internet is based on, experts say.

Source: www.theguardian.com

Photos Show Plastic Threatening Bird Populations on Paradise Island

Lord Howe Island

Neil Hadaway

Jutting out into the Tasman Sea between Australia and New Zealand is the curved, crescent-shaped volcanic remnant of Lord Howe Island. Measuring 10 kilometres in length and 2 kilometres at its widest point, the rocky island is covered in lush, unspoiled forest and boasts a sandy, coral-rich lagoon.

“This is paradise.” Neil HadawayA photographer who went there to document the activities of the marine research group. drifting“There are birdsongs all around, beautiful coral reefs and golden sand beaches.” Among the bird calls is the shearwater (Aldena CarneipesOf the total, approximately 22,000 breed on the island.

Petrel chick (Ardenna carneipes)

Neil Hadaway

But life there is not ideal, and newly hatched petrel chicks, like the one pictured above, are under threat from increasing marine plastic pollution. Adult petrels mistake plastic debris in the sea for food and end up feeding it to their young. In fact, Adrift researchers have found that the amount of plastic ingested by chicks is increasing every year. One of the team, pictured below, sifts through chunks of plastic in the stomach of just one bird.

As a result, these chicks become increasingly underdeveloped, with dozens dying each year from starvation and plastic-related diseases.

“This island may be magical,” Hadaway said, “but it's also full of frustration and sadness.”

He says stricter laws against plastic pollution are needed to protect populations of petrels, which locals affectionately call “muttonbirds” (see above) after their taste.

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Source: www.newscientist.com

Be prepared: A fungus is threatening to eradicate millions of ‘zombie cicadas’ in the US. Here’s what to expect.

It’s finally here. Once every 200 years, two flocks of periodical cicadas will emerge from the ground.

Across much of the US, billions of winged insects are emerging from the ground in search of a mating opportunity, but an unlucky few have been infected by a mysterious pathogen that is transforming them into flying insects. The salt shaker of death.

Are you locking the door and hiding under the covers? Before you do, hear this: Although zombie insects sound like the plot of a low-budget ’70s horror movie, they’re completely harmless to humans, plants, and pets, so feel free to marvel (probably from afar) as one of nature’s most powerful forces takes control.


Why do cicadas turn into zombies?

Cicada species live all over the planet, but the species currently abundant across the US are called “periodic cicadas,” which spend years underground as larvae before emerging as adults to mate.

Currently, two so-called “swarms” occur simultaneously in parts of the eastern U.S.: one that appears every 13 years, the other every 17. If you live in an area where this phenomenon is occurring, you’ll notice that it’s accompanied by a noise that’s louder than traffic.

The current occupation is expected to continue until the end of June, by which time most of the cicadas will have died and their eggs will have hatched and burrowed underground for another 13 to 17 years.

“One of the main reasons for this periodic emergence is to prevent predators from developing specialized ways to catch them,” says Dr. Jonathan Larson, an entomologist at the University of Kentucky. BBC Science Focus.

The only exception, Larson said, is Massospora cicadaina. “It’s likely that the disease will play a long game and remain dormant and not cause any symptoms until the cicadas emerge as adults above ground,” he said.

Once above ground, the infected cicada’s normally hollow body fills with white fungal spores and the abdomen bursts open to reveal what Larson describes as a “chalky white mass.”

Once exposed, the spores are free to infect other cicadas…

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How bacteria reproduce

Imagine a third of your body being filled with a harmful pathogen. You might not feel too great, and for good reason. However, infected cicadas can carry on with life as normal. In fact, the fungus changes the cicada’s behavior in some pretty significant ways.

“They can continue to act normally as if they are not infected, which allows them to continue spreading the virus,” Larson explains.

What is normal cicada behavior? After 17 years (or 13) underground, all they have on their mind is finding a mate. Male cicadas shake their abdomens to attract females, hence the loud explosion. Infected males do the same, killing unsuspecting females.

But the fungus has another trick up its sleeve.

“Female cicadas flap their wings in response to the loud, boisterous calls of males,” Larson explains, “but if the males are infected, they also start flapping their wings, fooling other males into thinking they’re mating with the female.”

How cicadas manage to stay alive with so many parts of their bodies packed with spores remains a mystery, but scientists have found some clues in recent years.

Billions of cicadas will emerge in the United States this year in a once-in-200-year event. – Image credit: Getty

For example, a study published in the journal Fungal Ecology It turns out that the fungus produces a type of amphetamine in its mass, which is used as a powerful human stimulant. Massospora Cicadina Will it stick?

Larson explains that it’s not clear exactly how the psychoactive substances affect the cicadas, but that the insects must be stimulated in some way. “That’s the real zombification part: They’re doing their job, they’re alive, but they’re just going through the motions. The lights are on, but no one’s home,” Larson says.

Should we worry about zombies?

First, the percentage of infected insects is very small, less than 5%, but 5% out of billions or even trillions of insects is still a lot of zombies flying around.

Thankfully, this fungus is specialized for cicadas. Massospora Cicadina ‘ is just a little hint so you don’t have to worry about infecting yourself.

“Transmission tends to be very localized, so while there are hotspots, it’s not common everywhere,” Larson said.

However, if you are planning to eat cicadas, you should definitely be careful. Yes, there are a lot of people out there who eat cicadas. Spicy Popcorn Cicada RecipeIf you’re interested, however, you should definitely avoid eating infected varieties.

“If you’re catching cicadas, the infected ones will be noticeably different,” Larson says. “If some fall off and you see a whitish lump, throw it away and don’t eat it.” Who would have thought eating insects infected with a pathogenic zombie fungus would be a bad idea? Everyone would.

About our experts

Jonathan Larson He is an entomologist and assistant professor at the University of Kentucky who provides his insect expertise to those dealing with problems in urban landscapes, lawns, nurseries, greenhouses and the home, and he is co-host of the informative insect podcast, The Insect Podcast. Arthropods.

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Source: www.sciencefocus.com