Tag Archives: acid

Scientists Express Concern Over Emerging Type of Acid Rain

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Researchers have raised concerns about a novel type of acid rain that is becoming increasingly prevalent, complicating efforts to mitigate its impact; I did it poses a hazard to all forms of life on Earth.

Trifluoroacetic acid (TFA) — a type of persistent “forever chemical” — is now found in rain and snow globally, in concentrations significantly higher than in past decades.

While the exact implications of TFA for human health and the environment remain unclear, some scientists are suggesting that these chemicals I did it may present an existential risk.

“Recent findings indicate that TFA can interfere with critical Earth system processes, such as mammalian embryo development and diminished soil respiration,” stated Professor Hans Peter Alp, a chemist at the Norwegian University of Science and Technology, in BBC Science Focus.

Professor Alp’s latest research categorized TFA as a planetary threat comparable to global warming and ozone depletion.

“We are uncertain about the long-term consequences,” he continued. “Due to the global accumulation of TFA, any long-term effects may manifest on a worldwide scale.”

“Moreover, when TFA impacts the environment, it does not break down naturally, making intervention too late. Existing technologies for TFA removal are prohibitively expensive and only applicable in limited scenarios.”

The ARP paper emphasized the necessity of taking proactive measures to curb the rapid buildup of TFA before it is officially deemed an emergency threat.

“In the heating and cooling sectors, this means we must avoid gases that lead to TFA formation,” Alp added.

“Another necessary step is to phase out pesticides and pharmaceuticals that produce TFA during degradation.”

Some nations have already begun taking action. Denmark is leading the charge, having banned 23 pesticide products in July 2025 due to their association with TFA contamination.

TFA is merely one of countless forever chemicals. Other PFAs are linked to health issues such as reproductive problems, fetal deformities, and various cancers – Credit: Chris Macrolin via Getty

TFA belongs to a category of “Forever Chemicals,” more formally known as polyfluoroalkyl substances (PFAs), which are notably resistant to degradation.

Among these persistent chemicals, TFA is one of the smallest. It can infiltrate the environment from sources such as refrigerants, aerosols, pesticides, air conditioning units, landfills, and sewage systems. When larger PFAs degrade, they often convert into TFA.

Because of its small size, TFA readily dissolves in water. This property contributes to its prevalence as a persistent chemical, as it is rapidly increasing not only in rain but also in rivers, lakes, groundwater, oceans, vegetation, food, and urine.

The ARP indicated that finding TFA in “previously untouched water resources” could be alarming. This is particularly troubling as TFA is considered nearly impossible to remove from drinking water.

Some scientists suggest that TFA may not pose significant risks to humans because it does not linger or accumulate in our bodies but is quickly excreted through urine.

However, the ARP maintains that new evidence shows an increasing presence of TFA in humans, animals, and ecosystems.

“We observe that TFA can penetrate cells, becoming integral components of lipids, proteins, and cellular structures. This may explain noticed alterations in microbial activity within soil,” stated ARP.

Researchers, including Alp, are exploring methods to eliminate TFA from the environment, such as cultivating crops that can absorb TFA.

Nonetheless, Alp emphasizes that further research is essential to assess the true level of threat posed by TFA. In the meantime, he urges that “the foremost priority is to curtail emissions before irreversible global consequences unfold.”

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About our experts

Professor Hans Peter Alp is a chemist at the Norwegian Geotechnical Institute and a professor at the Norwegian University of Science and Technology. His research focuses on how pollutants behave in environments that include microplastics, everlasting chemicals, metals, and more.

Source: www.sciencefocus.com

Chemists show the existence of sulfurous acid in the gas phase in normal atmospheric conditions

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Chemists at the Leibniz Institute for Tropospheric Research have discovered that sulfurous acid (H2So3), once formed in the gas phase, is kinetically stable enough to allow its characterization and subsequent reactions.

In the gas phase, sulfurous acid, once formed, exhibits some kinetic stability with a lifetime of at least 1 second in atmospheric water vapor conditions. Image courtesy of Berndt others., doi:10.1002/anie.202405572.

Sulfurous acid Having formula H2So3 The molecular weight is 82.075 g/mol.

This molecule, also known as sulfuric acid(IV) or thioic acid, is a difficult-to-reach acid that has never before been observed in aqueous solution.

However, sulfite Detected It was discovered in the gas phase in 1988 by dissociative ionization of diethyl sulfite.

“The only experimental detection of sulfurous acid to date was achieved in 1988 by the team of Helmut Schwarz at the Technical University of Berlin using in situ generation with a mass spectrometer,” said Dr. Torsten Berndt of the Leibniz Institute for Tropospheric Research and colleagues.

“Under vacuum conditions, we estimated an extremely short lifetime of more than 10 microseconds.”

“Theoretical calculations show that H2So3 As a possible reaction product of the gas-phase reaction of OH radicals with dimethyl sulfide (DMS), which are produced from ozone and water molecules in the troposphere primarily in the presence of ultraviolet light.”

“DMS is produced primarily by biological processes in the ocean and is the largest source of biogenic sulfur in the atmosphere, producing approximately 30 million tonnes per year.”

The researchers experimentally investigated possible reaction pathways to H.2So3 It starts with DMS.

Formation of H2So3 Its formation in the gas phase was clearly demonstrated in a flow reactor under atmospheric conditions.

“Under our experimental conditions, sulfurous acid remained stable for 30 seconds, regardless of humidity,” the researchers said.

“With the existing experimental setup, longer residence times have not yet been explored.”

“Therefore, H2So3 It may persist in the atmosphere long enough to affect chemical reactions.”

“The observed yields were somewhat higher than theoretically expected.”

According to related model simulations, about 8 million tons of H2So3 They form every year all over the world.

“In this pathway, the mass of H increases by about 200 times.2So3 Sulfuric acid (H2So4“It produces carbon dioxide (CO2) from dimethyl sulfide in the atmosphere,” said Dr Andreas Tilgner and Dr Eric Hofmann from the Leibniz Institute for Tropospheric Research.

“The new results may contribute to a better understanding of the atmospheric sulfur cycle.”

Team paper Published in the journal Applied Chemistry.

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Torsten Berndt others2024. Gas-phase production of sulfurous acid (H)2So3) floats in the atmosphere. Applied Chemistry 63(30):e202405572;doi:10.1002/anie.202405572

Source: www.sci.news

New study sheds light on amino acid metabolism and transport in tea plants

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High concentrations of free amino acids in tea leaves are important for tea’s flavor and health functions, but their biosynthesis, transport and turnover in the tea plant have remained unknown.

A practical model of nitrogen assimilation, amino acid synthesis, transport, and decomposition/recycling in tea plants. Image courtesy of Yu others., doi: 10.1093/hr/uhae060.

“Amino acids are essential for plant growth and have a significant impact on the flavor and health benefits of tea,” Professor Zhao Jian Hunan Agricultural University and colleagues.

“Especially the tea trees Camellia sinensis exhibits a unique amino acid profile that contributes to its distinctive taste and nutritional value.”

“Although the importance of amino acids such as theanine and glutamine (Gln) is known, the detailed dynamics of their synthesis, transport and degradation in tea plants remain unknown.”

“These challenges require intensive research to be carried out to understand the complex metabolic pathways and spatial distribution of amino acids within the tea plant.”

In the study, Professor Zhao and his co-authors analyzed the spatial dynamics of amino acid biosynthesis, transport and turnover in tea plants.

“This study provides a detailed analysis of the metabolic pathways and gene expression that control these processes,” the researchers said.

“By understanding these mechanisms, we hope to improve tea cultivation and enhance the quality of tea beverages.”

“This study revealed that nitrogen assimilation occurs mainly in the roots, where glutamate, theanine and arginine (Arg) are actively synthesized. These amino acids are then transported through the plant’s vascular system.”

“Transcriptome analysis revealed that genes involved in Arg synthesis are highly expressed in roots, whereas genes involved in Arg transport and degradation are expressed in stems and young leaves. This indicates that there is a sophisticated amino acid management system within the plant.”

“One of the key findings is the role of the CsGSIa gene, which is crucial for the synthesis, transport and recycling of amino acids.”

“Overexpression and knockdown experiments of CsGSIa in transgenic tea plants demonstrated significant effects on the levels of Gln and theanine.”

“The study also revealed that Arg, Gln, glutamic acid (Glu), and theanine are the major amino acids transported through xylem sap, facilitating long-distance nitrogen transport from roots to leaves.”

“Our findings provide a detailed map of amino acid metabolism in the tea plant, which is of vital importance for both basic science and applied agricultural practice,” Dr Zhao said.

“Understanding these metabolic pathways opens up new possibilities for breeding tea varieties with enhanced flavor and health benefits.”

The team’s findings have important implications for the tea industry.

“By elucidating the pathway of amino acid metabolism, our study paves the way for the development of tea plants with higher contents of beneficial amino acids, enhancing both flavour and nutritional value,” the researchers said.

“These insights can be applied to breeding programs and cultivation practices to produce superior tea varieties.”

“Furthermore, understanding these metabolic processes can help us develop strategies to improve nitrogen use efficiency, contributing to more sustainable and productive tea farms.”

of study Published in the journal Horticultural Research.

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Shuwei Yu others2024. Analysis of spatial dynamics of biosynthesis, transport and metabolism of major amino acids in tea plants (Camellia sinensis). Horticultural Research 11(5):uhae060; doi:10.1093/hr/uhae060

Source: www.sci.news

Study suggests ellagic acid as a promising dietary option for non-alcoholic fatty liver disease

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Ellagic acid is a polyphenolic, non-flavonoid compound found naturally in a variety of fruits, including pomegranates, raspberries, strawberries, and grapes, as well as nuts, including pistachios, pecans, walnuts, and acorns.

Senavirasna othersResearchers are investigating the effects of ellagic acid, an antioxidant found in pomegranates, raspberries, strawberries, grapes and nuts, in preventing and potentially reversing the damage caused by fatty liver disease. Image courtesy of Engin Akyurt.

Obesity is epidemic in many parts of the world and contributes to increasing rates of non-alcoholic fatty liver disease (NAFLD).

This rapidly expanding epidemic is the most common chronic liver disease worldwide.

The prevalence of NAFLD increased from 25.24% in 2015 to 29.38% in 2021.

NAFLD represents a range of pathologies from simple fatty liver (nonalcoholic fatty liver, NAFL) to nonalcoholic steatohepatitis (NASH), which can progress to more severe conditions including fibrosis.

Currently, no cure exists for the long-term management of NAFLD/NASH, but dietary interventions containing several polyphenolic compounds have been investigated for the treatment of NASH. Ellagic acid is one such compound.

“Ellagic acid, found in a variety of foods including raspberries, pomegranates, blackberries and pecans, is widely known for its antioxidant properties but has also demonstrated anti-inflammatory, anti-fibrotic and anti-cancer properties,” said researcher Lois Balmer and doctoral student Tarani Senaviratna, both from Edith Cowan University.

“Ellagic acid stands out as a remarkable polyphenolic compound with a wide range of pharmacological properties that may be promising for the treatment of various chronic diseases, including NAFLD.”

“Edible plants containing ellagic acid and its derivatives are recognized as valuable functional foods that promote human health due to their pleiotropic biological effects.”

“Furthermore, evidence suggests that ellagic acid may exert synergistic therapeutic effects when combined with other antioxidant dietary supplements, making it a potential candidate for combination therapy.”

The authors were involved in a previous pilot study investigating the effects of several polyphenolic compounds on NAFLD, with ellagic acid showing the most promise in reducing inflammation.

“Ellagic acid exerts its hepatoprotective properties mainly through scavenging free radicals, modulating cytokine production, and regulating lipid metabolism,” the researchers said.

“Ellagic acid, a potent antioxidant, combats reactive oxygen species (ROS) and activates the NrF2 pathway to reduce oxidative stress and protect the liver.”

“Surprisingly, ellagic acid also inhibits the Nf-kB and MAPK pathways, reducing inflammation during NAFLD/NASH.”

“Evidence also shows that ellagic acid can lower both triglyceride and cholesterol levels and combat de novo lipogenesis, a significant risk factor in the progression of NASH.”

“Test-tube findings suggest that ellagic acid has the ability to reduce fibrosis.”

“Urolithins, the main microbial metabolites of ellagic acid, have been shown to improve the gut microbiota in several mouse models of obesity.”

“Specifically, Urolithin A has been shown to lower LDL and increase HDL levels and is also involved in improving lipid metabolism through gene regulation, while Urolithin C activates the hepatic AMPK pathway, countering the pathophysiology of NAFLD.”

“While the health benefits of ellagic acid and urolithins in NAFLD/NASH are being debated, their biological effects on the liver are still poorly understood.”

“Given that lipid metabolism, oxidative stress, inflammation, and insulin resistance play a role in the development of NASH, the results of this review suggest that ellagic acid may be a potential dietary intervention for NASH, potentially suppressing and even reversing the pathological symptoms of NAFLD/NASH.”

of study Published in the journal Antioxidants.

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Tarani Senavilasna others2024. Elucidation of the therapeutic effects of ellagic acid on nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Antioxidants 13(4):485; doi:10.3390/antiox13040485

Source: www.sci.news