Tag Archives: endurance

Can Hormonal Implants Enhance Focus, Endurance, and Libido?

Posted on by
Reply

What is the future of hormone patches?

Phanie – Sipa Press / Alamy Stock Photo

Can flashy technology directly influence the regulation of hormones within your body and mind? By the year 2035, a myriad of options had emerged on the market. Morning pick-me-ups? Do you stimulate desire when you settle down for the night? Or perhaps a period of immunity to discomfort? It’s all now within reach.

This innovation began in 2027, when daily treatments for severe surface and internal abrasions were developed within a living dressing. This dressing belonged to a class of engineered Biological Materials (ELM) that produce enzymes and antibiotics to expedite healing.

ELM is also utilized in the production of fermented beverage kombucha, inspired by the biofilm that can form in vinegar. Known as the “mother” layer, biofilms are living substances and symbiotic cultures of bacteria and yeast (Scoby). In vinegar, Scoby transforms alcohol into acetic acid, while in kombucha, it generates acetic acid and other compounds from sweetened tea. However, crafting unique synthetic scobies (sin-sobies) with gene-edited yeasts and bacteria can generate the essential enzymes, nutrients, and hormones. In 2021, a team from Imperial College London developed programmable Scobys using Baker’s yeast, easily modified to produce various compounds.

The first widely adopted Syn-Scoby was a medical material, stored in a dormant state within emergency kits and surgical units. When required, the material, now referred to as the Heal Me patch, is extracted and applied to the affected area. Once exposed to oxygen, the yeast is reactivated to convert its cellulose matrix into the necessary compounds. These include protein-degrading enzymes that swiftly dismantle dead and damaged tissues, alongside other enzymes that mitigate pain and inflammation, thereby accelerating recovery.

Following successful medical applications, Syn-Scobys were devised in the 2030s for numerous uses, extending from contaminant detection in the environment to delivering vital nutrients, enzymes, and hormones. Syn-Scobys replaced the bionic pancreas utilized by individuals with type 1 diabetes for insulin production and blood glucose control. Other variants emitted a luminescent protein upon identifying specific contaminants, metals, or pathogens in the surroundings.

Military researchers created patches that produce adrenaline and testosterone to alleviate pain and enhance aggression. However, Heal Me patches had direct access to the bloodstream via human wounds, exposing the compounds to digestive enzymes before absorption. To counter this, scientists engineered patches intended to be implanted in the thighs or abdomen. When soldiers required a boost, an activating enzyme was injected at the implant site. This initiating enzyme activates the Syn-Scoby within the patch and releases the desired compounds into the bloodstream.

Activate your customized living implants to enhance focus, aggression, stamina, and pain tolerance.

Customized living implants can be triggered as needed to amplify focus, aggression, endurance, and pain resistance. Recreational Synscobi is designed to generate stimulants, psychedelics, and libido enhancers.

The array of embedded patches is now available for immediate use. They secrete leptin to mimic solid leptin and inhibit ghrelin, which triggers hunger. Another variant allows live implants to produce semaglutide drugs such as Mounjaro, Wegovy, and Ozempic to suppress the urge to eat or drink, focusing on generating drugs like modafinil and oxiracetam that enhance cognitive function and memory retention.

For recreational purposes, psychoactive compounds like psilocybin are secreted, easily synthesized from gene-edited yeast. Users are filled with oxytocin and serotonin, fostering feelings of love, joy, and sexual desire. Dream Me facilitates controllable dreaming and stages of restful sleep, offering two options: Lucid and Black Out.

The most exclusive and sought-after implant was the Juve Me series, which generated various anti-aging compounds known as cytopathy and gathered senomorphic substances such as rapamycin and metformin that clear senescent cells and rejuvenate aged cells. Unlike many other ELMs, which have a temporary existence within the body before being metabolized, Juve Me implants were purposefully designed to be self-sustaining. It represents a symbiotic being living harmoniously within a fortunate individual, supplying nutrients essential for the implant’s longevity and vitality.

Hat Tips for Iain M. Banks’s culture The novels serve as inspiration for my symbiotic implants, which align with the bank’s concept of “Granding.”

Rowan Hooper is the podcast editor for New Scientist and author of How to Spend $1 Trillion: These are 10 global issues that can realistically be addressed. Follow him on Bluesky @rowhoop.bsky.social

Topic:

  • Medical Technology/
  • Health

Source: www.newscientist.com

For the First Time, NASA’s Endurance Mission Measures Earth’s Bipolar Electric Field

Posted on by
Reply

First hypothesized over 60 years ago Bipolar electric field Polar winds are the primary driver of a constant outflow of charged particles into space above the Earth’s poles. These electric fields lift charged particles in the upper atmosphere to higher altitudes than usual, and may have shaped the evolution of Earth in ways that are still unknown.

Collinson othersThey report that a potential drop of +0.55 ± 0.09 V exists between 250 km and 768 km due to the planetary electrostatic field, generated solely by the outward pressure of ionospheric electrons. They experimentally demonstrate that the Earth’s ambipolar field controls the structure of the polar ionosphere, increasing its scale height by 271%. Image courtesy of NASA.

Since the 1960s, spacecraft flying over Earth’s poles have detected streams of particles streaming from Earth’s atmosphere into space.

Theorists predicted these outflows, named them polar winds, and stimulated research to understand their causes.

Some outflow from the atmosphere was expected — intense, unobstructed sunlight should send some atmospheric particles escaping into space, like water vapor evaporating from a pot of water — but the observed polar winds were more puzzling.

Many of the particles inside were cold and showed no signs of heating, but they were moving at supersonic speeds.

“Something must be attracting these particles to the outer reaches of the atmosphere,” said Dr. Glynn Collinson, Endurance mission principal investigator and a researcher at NASA’s Goddard Space Flight Center.

The electric fields, hypothesized to be generated at subatomic levels, would be incredibly weak and their effects would be expected to be felt only for distances of hundreds of miles.

For decades, detecting it has been beyond the limits of existing technology.

In 2016, Dr Collinson and his colleagues began inventing a new instrument that they thought would be suitable for measuring Earth’s bipolar magnetic field.

The team’s equipment and ideas were perfectly suited for a suborbital rocket flight launched from the Arctic.

The researchers named the mission “Antarctic Expedition,” in honor of the ship that carried Ernest Shackleton on his famous 1914 Antarctic voyage. Endurance.

They set course for Svalbard, a Norwegian island just a few hundred miles from the North Pole and home to the world’s northernmost rocket launch site.

“Svalbard is the only rocket launch site in the world that can fly through the polar winds and make the measurements we need,” said Dr Susie Ingber, an astrophysicist at the University of Leicester.

Endurance was launched on May 11, 2022, reaching an altitude of 768.03 kilometers (477.23 miles) and splashing down in the Greenland Sea 19 minutes later.

Over the 518.2 kilometres (322 miles) altitude where Endurance collected data, it measured a change in electrical potential of just 0.55 volts (V).

“Half a volt is almost meaningless – it’s about the strength of a watch battery – but it’s just right for describing polar winds,” Dr Collinson said.

Hydrogen ions, the most abundant type of particle in the polar wind, experience an outward force from this field that is 10.6 times stronger than gravity.

“That’s more than enough to counter gravity, in fact to launch you into space at supersonic speeds,” said Dr. Alex Grosser, a research scientist at NASA’s Goddard Space Flight Center and Endurance project scientist.

Heavier particles are also accelerated: an oxygen ion at the same altitude, immersed in this 0.5 volt electric field, loses half its mass.

In general, scientists have found that bipolar magnetic fields increase what’s called the scale height of the ionosphere by 271%, meaning the ionosphere remains denser up to higher altitudes than it would be without the bipolar magnetic field.

“It’s like a conveyor belt that lifts the atmosphere up into space,” Dr Collinson said.

The Endurance discovery has opened up many new avenues of exploration.

The polarity field, as a fundamental energy field of the Earth alongside gravity and magnetism, may have continually shaped the evolution of the atmosphere in ways that we are only now beginning to explore.

Because it is generated by the internal dynamics of the atmosphere, similar electric fields are expected to exist on other planets, including Venus and Mars.

“Any planet with an atmosphere should have a bipolar magnetic field, and now that we’ve finally measured it we can start to learn how it has shaped our planet and other planets over time,” Dr Collinson said.

Team result Published in a journal Nature.

_____

G.A. Collinson others2024. Earth’s bipolar electrostatic field and its role in the escape of ions into space. Nature 632, 1021-1025;doi:10.1038/s41586-024-07480-3

This article is a version of a press release from NASA Goddard Space Flight Center.

Source: www.sci.news

New insights uncovered by scientists on the transformative effects of endurance training on muscles

Posted on by
Reply

Researchers at the University of Basel have conducted a study on muscle adaptations in mice and discovered that endurance training leads to significant muscle remodeling. This is evident in the differential gene expression in trained muscles compared to untrained muscles, with epigenetic changes playing a crucial role in these adaptations. Trained muscles become more efficient and resilient, allowing for improved performance over time. The findings shed new light on the mechanisms behind these muscle adaptations.

Endurance training comes with numerous benefits. Regular exercise not only enhances overall fitness and health but also brings about substantial changes in muscle structure. This results in decreased muscle fatigue, increased energy production, and optimized oxygen usage. The recent experiments conducted by researchers at the University of Basel, using mice as subjects, have further elucidated these muscle changes.

Professor Christoph Handsin, who has extensive experience in muscle biology research at the Biozentrum University of Basel, explains that it is well-known that muscles adapt to physical activity. The goal of their study was to gain a deeper understanding of the processes occurring in muscles during athletic training. The researchers found that training status is reflected in gene expression.

Comparing untrained and trained mice, Handsin’s team examined the changes in gene expression in response to exercise. Surprisingly, they discovered that a relatively small number of around 250 genes were altered in trained resting muscles compared to untrained muscles. However, after intense exercise, approximately 1,800 to 2,500 genes were regulated. The response of specific genes and the degree of regulation depended largely on the training condition.

Untrained muscles activated inflammatory genes in response to endurance training, which could lead to muscle soreness from small injuries. In contrast, trained muscles exhibited increased activity in genes that protect and support muscle function, allowing them to respond differently to exercise stress. Trained muscles were more efficient and resilient, enabling them to handle physical loads better.

The researchers found that epigenetic modifications, chemical tags in the genome, played a crucial role in shaping muscle fitness. Epigenetic patterns determine whether genes are turned on or off, and the patterns differed significantly between untrained and trained muscles. The modifications affected important genes that control the expression of numerous other genes, ultimately activating a distinct program in trained muscles compared to untrained muscles.

These epigenetic patterns determine how muscles respond to training. Chronic endurance training induces short and long-term changes in the epigenetic patterns of muscles. Trained muscles are primed for long-term training due to these patterns and exhibit faster reactions and improved efficiency. With each training session, muscular endurance improves.

The next step for researchers is to determine whether these findings in mice also apply to humans. Biomarkers that reflect training progress can be used to enhance training efficiency in competitive sports. Additionally, understanding how healthy muscles function is crucial for developing innovative treatments for muscle wasting associated with aging and disease.

In conclusion, the study conducted by researchers at the University of Basel has unveiled the mechanisms through which muscles adapt to regular endurance training in mice. The insights gained from these findings may have implications for human performance and health. Furthermore, understanding muscle function can aid in the development of treatments for muscle-related conditions.

Source: scitechdaily.com