Bulgarian Yogurt: A Key Factor in Colonizing Mars?

space yogurt

Could Bulgarian yogurt improve astronauts' performance during Mars missions?asks Isabella Shopova, Diana Bogeva, Maria Yotova, and Svetla Danova in a study about that name published in “. ethnic food journal.

Researchers had seven people make and eat Bulgarian-style yogurt. Lactobacillus delbrueckiiSubspecies bulgaricus and thermophilus. At the time, the seven were members of a “team of analog astronauts participating in a two-week analog mission in a closed Mars-like environment at the Mars Desert Research Station in the Utah desert, USA.”

Most of these astronauts who stayed on Earth were not simply yogurt eaters. The study found that “five out of seven crew members had previously consumed yogurt in some form.”

The experiment extends a research tradition in which Bulgarian yogurt was ingested during the space flight of the second Bulgarian astronaut to date, as well as the crew of a 150-day voyage to Antarctica, and 56 of the Bulgarian Air Force. Also eaten by pilots and similar people. Number of volunteers in “simulated shipwreck situation”.

Scientists ahead of the Mars mission reported success, saying: “Bulgarian yogurt has proven to be a valuable food product for colonization of Mars due to its long shelf life and probiotic properties.” Reporting. This “underlines the versatility of Bulgarian yogurt,” they say. They outline the hope that further research will provide insight into changes in gut microbiome diversity and “flatulence frequency.”

in the name of science

Taken together, the scientific names of living organisms are a hodgepodge. Richard Wakeford warns of feedback on attempts. Proceedings of the Royal Society Bto enjoy the diversity.

In their paper, “Zoo naming: Creativity, culture, and influence in the formation of scientific names.'', Stephen B. Heard of the University of New Brunswick and Julia J. Mlinarek of the Insectarium de Montréal, in Canada, survey the diversity and lament its difficulties.

Source: www.newscientist.com

Decoding the key to aging well with medaka fish

A study of killifish by the Max Planck Institute revealed that older fish enter a state of starvation due to changes in their adipose tissue. Activating a specific subunit of AMP kinase restores health and longevity in humans, suggesting a new way to promote healthier aging in humans.

Genetic switch rescues aging fish from starvation trap.

Fasting interventions that alternate between fasting and refeeding are generally thought to improve health. However, these interventions do not work well in older animals.

The question is, why?

By studying short-lived killifish, researchers at the Max Planck Institute for the Biology of Aging in Cologne found that older fish deviate from the fasting and refeeding cycles of their youth, and even when they consume food, they permanently It was shown that the body enters a state of fasting. However, the benefits of post-fasting refeeding in old medaka fish can be restored by genetically activating specific subunits of AMP kinase, an important sensor of cellular energy.

These mutant fish experience improved health and longevity and require both fasting and refeeding to provide health benefits, which have been shown to act through AMP kinase. I am.

Medaka ages rapidly. The bright colors of their youth fade in just a few months.Credit: K. Link / Max Planck Institute for the Biology of Aging

It has already been shown in many model organisms that reducing food intake through calorie restriction or periods of fasting has positive effects on health. However, it is difficult for humans to reduce the amount they eat throughout their lifetime. To find the optimal timing for fasting, researchers introduced fasting interventions at different ages, but found that these interventions in older adults did not provide the same benefits as in younger animals.

A research team in Cologne, Germany, now investigated the effects of age-related fasting on medaka fish. Medaka is a rapidly aging fish that grows from young to old in just a few months. The researchers either starved young and old fish for several days or fed them twice a day. They found that the visceral adipose (adipose) tissue of older fish became less responsive to feeding. “Adipose tissue is known to respond most strongly to changes in food intake and plays an important role in metabolism, which is why we looked at it more closely,” said lead author of the study. explains Roberto Ripa.

It is important to alternate between fasting and meals

The researchers found that, unable to respond to the feeding phase, the adipose tissue of old fish enters a permanent state of starvation, where energy metabolism ceases, protein production decreases, and tissue does not renew. “We thought that older fish would be unable to switch to fasting after feeding. Surprisingly, the opposite was true, and older fish would be unable to switch to fasting after feeding. , they were in a state of permanent starvation,” said study leader Adam Antebi, director of the Max Planck Institute for the Biology of Aging.

Permanently fasted adipose tissue

When the researchers looked more closely at how the fat tissue of old fish differs from that of young fish, they discovered a specific protein called AMP kinase. This kinase is a cellular energy sensor and is composed of various subunits, among which the activity of the γ1 subunit decreases with age. When scientists genetically engineered this subunit to increase its activity, the starvation-like state was overcome, and the old fish became healthier and lived longer.

human aging

Interestingly, an association was also found between the γ1 subunit and human aging. Significantly lower levels of certain subunits were measured in samples from older patients. Additionally, in human samples, we were able to show that people who are less frail at older ages have higher levels of the γ1 subunit.

“Of course, we still don’t know whether the human γ1 subunit is actually involved in healthy aging. The next step is to find a molecule that precisely activates this subunit and use it to “We investigate whether this can have a positive impact on aging,” explains Adam Antebi.

Reference: “Refeeding related AMPK”γ1 Complex activity is a hallmark of health and longevity.” Roberto Ripa, Eugen Barrissa, Joachim D. Steiner, Raymond Lavoie, Andrea Annibal, Nadine Hocher, Christian Razza, Luca Dolfi, Chiara Calabrese, By Anna M. Meyer, Maria Cristina Polidori, and Roman – Ulrich Müller and Adam Antebi, November 13, 2023, natural aging.
DOI: 10.1038/s43587-023-00521-y

Source: scitechdaily.com

Gogoro’s Decision to Enter the Indian Market as a Key Move

Co-founder of Gogoro, CEO Horace Luke says Taiwanese companies want to “grow big” in India despite the challenges they face at home. India’s potential seems ripe to simply ignore, and not just because India is the world’s largest two-wheeler market with 15 million to 20 million new two-wheelers on the road each year. Luke also sees the world’s most populous country as a springboard to accelerate global expansion into other markets. This is not a bad strategy considering that India is already making strides to become a competitive manufacturing hub for all major international brands and products, from smartphones to satellites. Earlier this month, Gogolo made its first commercial entry into India with the introduction of a battery swapping network and smart scooters after piloting and investing millions of dollars in the country. Speaking with Luke on the sidelines at a company event, it’s clear that his ambitions extend beyond this initial debut of his. Founded in 2011 by former HTC executives Luke and Matt Taylor, Gogoro sees itself as the Android of all EVs. The company sells its own branded scooters with replaceable batteries, as well as providing its proprietary technology to other automakers. In addition to its home base of Taiwan, the company already operates in markets such as China, Indonesia, Singapore, Israel, and the Philippines. Speaking at the company’s launch in New Delhi, Luke said the company has chosen India as a strategic market where it can gain many new users and enter new markets, starting with neighboring Nepal. These new developments include an initial battery swapping pilot in Delhi and a partnership with Bellrise Industries to invest a total of $2.5 billion in Maharashtra to build battery swapping infrastructure and networks in the western peninsula. This follows Gogoro’s previous announcement in India. The state government invested his $25 million in electric vehicle management startup Zypp Electric. Luke said Gogoro is in talks with various local and global companies to expand its operations and presence in India, without disclosing their names. The company is already working with domestic manufacturers to produce components locally and is currently partnering with Foxconn to assemble them at a facility in Maharashtra. The company is also looking to partner with Indian and global automakers who can deploy its technology to help grow their businesses in India. The company has about 11 automakers in Taiwan, which manufacture vehicles in various sizes and configurations based on standard battery sizes, the executive said. These include Suzuki, Yamaha, Ion Motor, and more. He suggested that some of them could be introduced in India along with Gogoro’s replaceable battery technology in the future. “Everyone is waiting for me to bring the network,” Luke said, without providing specific details. “Once the network is up and running, [partners] Bring out their abilities and abilities. ” In April 2021, Gogoro partnered with Hero MotoCorp, a major Indian two-wheeler company, to roll out a battery exchange network in the country. However, this deal has not yielded any results. When asked how Gogoro will leverage its partnership with Hero MotoCorp and why it didn’t choose a local automaker to debut and instead bring its own smart scooters to the country, Luke gave a rough answer. Sharing the answer, the management of Hero MotoCorp said that they did so. I wish him all the best before the release. “their [Hero MotoCorp] The brand and the company as a whole is very B2C focused…We’re launching with a B2B focus first, so we try to keep them informed about everything that’s going on,” he says. I did. “We are an open platform. One day they will be ready. [to] Start your vehicle using our system.But what really came first, the chicken or the egg? [situation]. They need to prove that they have a ready platform before they can actually come in and do that. ” Copying the Taiwanese model Gogoro plans to simulate Taiwan’s growth in India by opening 30 stations in Delhi by the first quarter of 2024. The company started operations in Taipei with the same number of stations, but has since expanded to his 12,500 stations serving approximately 600,000 vehicles across Taiwan. We are ready to invest more in India to reach that level and grow even bigger over time. “If you think about Pan India, by 2030-2032 it will easily be in the billions of dollars,” Luke asserted. He told reporters at the launch that Gogoro’s battery swapping system accounts for 93% of all electric vehicles in Taiwan, of which about 80% use its own brand vehicles. In its home country, the company is not limited to two-wheelers but also provides replacement battery technology to players operating autorickshaws. Nevertheless, as Luke admitted to TechCrunch, Gogoro’s growth has stalled and is also declining in Taiwan. among them Recent earnings report [PDF]the Nasdaq-listed company said its revenue fell 10.2% from a year ago to $91.8 million and its net loss was $3.1 million, down from net income of $56.4 million in the year-ago period. He emphasized that there are several reasons for the deterioration of the financial situation and the withdrawal of the Taiwan business. First, he said, is due to lobbying against the speed of electric vehicle adoption after the 2020 election. Second, the country has been slow to recover from the COVID-19 pandemic. “Taiwan has always been a pilot for us,” Luke said. “India has always been a market where we develop technology and develop systems so that when we come to India, we are ready. And that’s where the point is now.” He said gasoline in Taiwan is subsidized to the point where it is available at an average price of 0.85 cents per liter, which is significantly cheaper than India’s average price of $1.4 per liter and higher than the world price of $1.22 per liter. did. Although Gogoro is optimistic about starting operations in India, the country has its challenges. relatively small market The share of EVs is only 3.7% of the country’s total car market. Electric scooters account for 90% of total EV sales in the country, but only about 5% of the total motorcycle market. The Indian government is allocated billions of dollars Subsidy and discount systems to attract manufacturers and commuters to EVs. However, these advantages are only sustained for a short period of time, and the electric two-wheeler market has recently been disrupted by structural changes. But Gogoro, like other players in the EV market, is bullish as the Indian government targets 30% EV adoption by 2030. Gogoro’s approach of considering India as a manufacturing base is also likely to appeal to the government and help the company make some changes. Move production from China and enter new markets. It’s important to note that while GoGoro’s revenue decreased significantly last quarter, its battery replacement service continued to grow, with revenue increasing 10.4% year-over-year to $33.6 million. The company is considering collaborating with other automakers in India on battery replacement technology, which could be a mutually beneficial move for both Gogoro and the automaker. The Indian automotive industry is actively seeking solutions to reduce charging times and provide efficient alternatives to ICE vehicles. By offering its technology to automakers, Gogoro can capitalize on this need and increase revenue from battery replacement services. A recent report co-authored by Bain & Company and Blume Ventures forecast Battery-free electric two-wheelers can reduce the initial cost of a vehicle by 40-50%, thereby attracting price-sensitive Indian customers. But at the same time, he cautioned that building a battery replacement ecosystem in India will be difficult in the short term, saying that maintaining battery replacement inventory of top SKUs across manufacturers, identifying targeted customer segments, and creating a “walled-in” ecosystem will be challenging in the short term. proposed to establish a partnership between the two countries. Supports replaceable battery system. One investor told TechCrunch that to truly succeed, the market needs interoperability and standardization of battery swapping, similar to how today’s mobile phones have USB-C. . But for Gogoro, this is just the beginning of exploring how much of an impact he can have on the overall EV market with available battery replacement solutions. “We’ve got a whole ecosystem that we need to deploy. It took us a little while to get it ready, but it’s going to take a little while to get up and running. Besides, who said this was going to…

Source: techcrunch.com

Experts Uncover the Key to Student Success in Education

Research by the University of South Australia and its partners shows that increasing student engagement with complex learning tasks significantly improves critical thinking and problem-solving skills. This study suggests that teachers should focus on deep learning techniques to improve student outcomes.

High engagement, high returns. This is advice from education experts at the University of South Australia for teachers looking to improve student performance.

In a new study conducted in partnership with
flinders university
Researchers from the Melbourne School of Education found that fewer than a third of teachers engage students in complex learning, limiting students’ opportunities to develop critical thinking and solve problems. Did.

Researchers who filmed and assessed classroom content in South Australia and Victoria found that nearly 70% of student assignments consisted of simple questions and answers and notes, rather than activities that engaged students on a deeper level. I found that it is related to superficial learning such as taking things and listening to the teacher.

Emphasis on deep learning

UniSA researcher Dr Helen Stevenson said teachers needed more support to plan interactive and constructive lessons that foster deep learning.

“When it comes to learning, the greater the engagement, the deeper the learning. But too often, students are not very active and do passive work,” says Dr. Stevenson. Masu

“Our research suggests that about 70% of classroom content may be ‘passive’ (students have little observable input), or doing something simple like answering questions on a fact sheet. was considered to be “active”. While there is certainly a place for such tasks in the classroom, student learning is greatly enhanced when students spend more time doing complex activities that promote deep conceptual learning. Deep learning requires organizing knowledge into conceptual structures, which has been shown to improve information retention and improve learning outcomes. Deep learning also supports the knowledge needed for innovation. Making small changes to teachers’ existing lesson plans and instruction can significantly increase student engagement, which in turn improves overall outcomes. ”

She continues: “At a basic level, teachers need to consider how they can adjust existing classroom activities to place more tasks deeper into the learning scale. For example, suppose you watch a video. . Students can watch the video silently (this is “passive”). Watch the video and take notes using the presenter’s words (this is considered “active”). Write any questions that arise while watching the video (this is “constructive”). Or watch the video and discuss it with other students to generate different ideas (this is ‘interactive’). Interactive classroom engagement involves students participating in activities with other students and receiving stimulation that fosters deeper understanding. They make judgments, propose and criticize arguments and opinions, and come up with solutions to problems. These activities also help develop critical thinking and reasoning skills. All of these are predictive of learning gains. ”

Survey results regarding teacher awareness

Interestingly, one of the study’s key findings is that many teachers do not recognize or fully appreciate the importance of how classroom assignments can stimulate different modes of student participation. It seems like it hasn’t.

“Simply changing class activities from ‘active’ to ‘constructive’ can go a long way in improving student learning,” says Dr. Stevenson.

“Teachers should be supported to engage in professional development to shift their thinking to practices that support deeper learning and better outcomes for students.”

References: “Using the Extended ICAP-Based Coding Guide as a Framework for Analyzing Classroom Observations,” by Stella Vosniadou, Michael J. Lawson, Erin Bodner, Helen Stephenson, David Jeffries, and I Gusti Ngurah Darmawan; April 13, 2023 Education and teacher education.
DOI: 10.1016/j.tate.2023.104133

This research was funded by the Australian Research Council.

Source: scitechdaily.com

Is Pulsar Light the Key to Solving the Dark Matter Mystery?

New research explores the possibility that dark matter is composed of theoretical particles called axions, and focuses on detecting them through additional light from pulsars. Although axions have not yet been confirmed in early observations, this research is critical to understanding dark matter.

A central question in the ongoing search for dark matter is: What is dark matter made of? One possible answer is that dark matter is made up of particles known as axions. A recent study by astrophysicists at the University of Amsterdam and Princeton University suggests that if dark matter is indeed made of axions, it could manifest itself in the form of subtle additional glow emanating from pulsating stars.

Dark matter may be the most sought-after building block in our universe. Remarkably, this mysterious form of matter, so far undetectable by physicists and astronomers, is thought to make up a huge portion of what exists on Earth. It is suspected that more than 85% of the matter in the universe is “dark”, and at the moment it is only recognized by the gravitational force it exerts on other celestial bodies. Naturally, scientists want to look directly detect its existence rather than just inferring it from gravitational effects. And of course they want to know what of course, solve two problems One thing is clear: dark matter cannot be the same kind of matter that makes up you and me. If so, dark matter would simply behave like ordinary matter. Dark matter will form star-like objects, will glow, and will no longer be “dark.” So scientists are looking for something new, a type of particle that no one has detected yet, and perhaps one that only interacts very weakly with the types of particles we know about.

One common hypothesis is that dark matter may be made of: Axion. This hypothetical type of particle was first introduced in the 1970s when he solved a problem that had nothing to do with dark matter. The separation of positive and negative charges inside a neutron, one of the building blocks of a normal atom, turns out to be unexpectedly small. Of course, scientists wanted to know why. It turns out that the presence of a previously undetected type of particle that interacts very weakly with components of neutrons can cause just such an effect. Frank Wilczek, who later won the Nobel Prize, came up with the name for this new particle. Axion – as well as similar to another particle name such as protons, neutrons, and electrons. photon, but it’s also inspired by the laundry detergent of the same name. Axion existed to solve problems. In fact, it might clean up the two even if it’s not detected. Several theories about elementary particles, including string theory, one of the leading candidate theories for unifying all the forces in nature, seem to predict the possibility of axion-like particles.

Fortunately, there appears to be a way out of this conundrum for axions. If the theory predicting axions is correct, not only would axions be expected to be produced in large quantities in the universe, but some axions could also be converted to light in the presence of strong electromagnetic fields. If there is light, we can see. Could this be the key to detecting axions and, by extension, dark matter? To answer this question, scientists first had to ask themselves where in the universe the strongest known electric and magnetic fields occur. The answer is known in the region around rotating neutron stars. pulsar. These pulsars (short for “pulsating stars”) are dense objects with a mass about the same as the Sun, but a radius about 100,000 times smaller, or only about 10 km. Because pulsars are so small, they rotate at enormous frequencies and emit bright, narrow beams of radio radiation along their axis of rotation. Just like a lighthouse pulsarThe beam can sweep across the Earth, making it easy to observe the pulsating star. But the pulsar’s massive rotation does more than that. it is, neutron star It turns into a very powerful electromagnet. That could mean Pulsar is a highly efficient axion factory. The average pulsar can produce 50 orders of magnitude axions per second. Because of the strong electromagnetic fields surrounding pulsars, some of these axions can be converted into observable light.

As always in science, carrying out such observations in practice is, of course, not so easy. The light emitted by axions (which can be detected in the form of radio waves) is only a fraction of the total light these bright cosmic lighthouses send back to us. Much less can we quantify the difference and turn it into a measurement of the amount of dark matter. This is exactly what a team of physicists and astronomers are currently doing. Through a collaboration between the Netherlands, Portugal, and the United States, the research team has uncovered details about how axions are created, how axions escape the neutron star’s gravity, and…

First observational tests were performed on the theory and simulation results…referencesystem, simulate a subtle glow

Next, first observational tests were performed on the theory and simulation results…referencesystem to show that it is very unlikely that axions are a component of…s

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Source: scitechdaily.com