Should Scientists Have the Authority to Edit Animal Genes? Some Conservation Groups Say Yes

“The technology has arrived and is currently unfolding,” stated Susan Lieberman, vice president of international policy at the Wildlife Conservation Society. “There may be instances where genetically modified organisms can be cautiously and ethically tested and introduced into natural environments.”

He remarked that the new framework represents a “transformative advancement” that may enable conservationists to explore innovative solutions to climate change challenges and to assess new methods for disease control.

The IUCN consists of a vast coalition of conservation organizations, governments, and indigenous communities, boasting over 1,400 members from roughly 160 nations, convening once every four years. It stands as the globe’s largest network of environmental organizations and is responsible for the Red List, which monitors endangered species and global biodiversity.

This year’s conference took place in Abu Dhabi, where the vote favoring “synthetic biology” established a new framework for assessing genetic engineering initiatives and their potential implementation. This measure mandates that scientists evaluate such projects on an individual basis, maintain transparency regarding the associated risks and benefits, and adhere to precautionary principles relating to genetic engineering. This applies to a spectrum of organisms, including animals, plants, yeast, and bacteria.

Another proposal, which aimed to suspend the release of genetically modified organisms into the environment, failed by a narrow margin of one vote.

Jessica Owley, a professor and director of the environmental law program at the University of Miami, noted that while the IUCN decision lacks legal force, it carries symbolic importance and could influence international policy.

“IUCN is a powerful and recognized entity in the conservation field. Their word holds weight, and governments pay attention. They play a significant role in various treaties,” she commented. “This can be viewed as groundwork for future legal language.”

Organizations advocating for a moratorium on the release of genetically modified organisms into the wild argue that there is insufficient evidence to prove it can be done safely and responsibly.

“We’re disappointed,” stated Dana Perls, senior food and agriculture program manager at the nonprofit Friends of the Earth. “Our focus should be on confined research that doesn’t turn our environment into a live experimental lab.”

As a potential example, she cited: genetically modifying mosquitoes to combat the malaria-causing parasite. The disease claims over 500,000 lives annually, prompting scientists to propose spreading this malaria resistance across broader mosquito populations through a method known as genetic drive.

Source: www.nbcnews.com

Will a Ban on Genetic Engineering in Wildlife Hinder Conservation Efforts?

The concept of genetically modifying wild lions sparks debate

Andrewfel/Shutterstock

Is there a need to genetically modify wild lions? While it may seem unnecessary, it provokes a quick reaction. Consider a scenario where a devastating disease, introduced by humans, threatens their survival. What if genetic alterations could boost immunity against this disease, providing a natural evolution path through time as more lions perish?

This debate is fracturing the environmentalist community, with discussions set to intensify. Next week, at a meeting of the International Union for Conservation of Nature (IUCN)—the leading conservation organization—delegates will vote on a proposal to “suspend” genetic engineering in wildlife, including the introduction of modified microorganisms.

“I’m uncertain how the voting will unfold,” says Piero Genovesi from the Italian Institute of Environmental Protection, who backs an open letter opposing the proposal.

While the IUCN’s moratorium on synthetic biology carries no legal weight, it may still have significant repercussions. Various conservation organizations might halt projects involving genetic engineering, and some nations could incorporate such restrictions into their laws.

“Moratoriums would undoubtedly pose challenges on various fronts,” states Ben Novak, of the US-based nonprofit Revive & Restore, which aims to leverage biotechnology for the recovery of endangered and extinct species.

Why is this issue gaining attention now? The answer lies in CRISPR. In 2014, the potential for gene drives using CRISPR technology was demonstrated. Gene drives allow specific DNA segments to be passed down through generations, enabling them to spread even if detrimental. This technology could theoretically eliminate invasive species or spread beneficial traits like disease resistance.

Discussions emerged at a 2016 conference in Hawaii regarding employing gene drives to eradicate invasive mosquitoes that have decimated Hawaii’s native bird species, according to Genovesi. Reactions were mixed; some were enthusiastic, while others expressed deep concern.

This tension led to the proposed moratorium. “Gene drives are being promoted by some as a one-size-fits-all solution to environmental issues,” mentions Ricarda Steinbrecher from Econex, an organization also advocating for the moratorium.

However, the broad language of the proposed motion could affect much more than just gene drives. It might unintentionally restrict passive conservation efforts and the use of live vaccines.

Steinbrecher suggests the moratorium is a temporary halt, indicating another vote may take place later “when more data becomes available.” However, with many proponents of the ban being staunchly against genetic engineering, changing their perspectives may be challenging. “I’m concerned it could lead to an extended pause,” Genovesi states.

Imagine the prospect of using gene editing to make wild animals disease-resistant. While Steinbrecher raises concerns about unintended consequences, current evidence suggests the risks remain low. This is why some genetically edited foods are already being consumed, and the first CRISPR therapy received approval last year.

The same considerations regarding benefits and risks are applicable to conservation efforts. For instance, is it preferable to witness global warming decimating coral reefs rather than releasing genetically engineered symbiotic algae to enhance coral heat tolerance?

The scalability of such endeavors is crucial, asserts Novak. Manual transplanting of corals will not be enough to salvage the reefs. “Synthetic biology tools are essential for achieving the broad objective of restoring 30% of land and saving seed varieties,” he emphasizes.

Ultimately, this discourse revolves around conflicting visions of nature. Some regard it as a pristine entity, wary of genetic modification. Nonetheless, humans have already altered nature significantly. Our actions have unintentionally interfered with genetic selection through practices like hunting, pollution, pesticide use, and the introduction of invasive species and diseases.

These actions necessitate adaptations among many species for their survival; for instance, specific elephant populations are now nearly devoid of tusks.

However, this does not imply that further interference will yield positive outcomes. The release of gene drives carries significant risks, such as their potential spread beyond intended targets.

Researchers are cognizant of these hazards. Methods like self-limiting gene drives can be implemented to prevent unrestrained gene dispersion.

“We are confronted with a severe biodiversity crisis,” Genovesi argues. “We shouldn’t close ourselves off to innovative tools that could assist us in combatting substantial threats.”

Conservation and Rewilding in the Central Apennines: Italy

A journey through Italy’s central Apennines introduces the practical realities and philosophy behind rewilding.

Topics:

Source: www.newscientist.com

Innovative Wildlife Conservation Strategies Emerge in Guatemala Due to Climate Change

Research conducted by the Wildlife Conservation Association highlights the diverse wildlife that frequents artificial watering holes in the Mayan forests of Guatemala.

Jaguars find respite from the heat in Guatemala’s artificial waterfall hole. Image credit: WCS Guatemala.

As temperatures rise in Mesoamerica, protected areas in northern Guatemala are confronting increasing ecological challenges, primarily due to severe water shortages negatively impacting local wildlife.

In response, the conservation organization has taken proactive measures to safeguard biodiversity in two key ecosystems: Laguna del Tigray National Park and Mirador Rio Azur National Park.

To tackle this pressing concern, strategic installations of artificial waterfall holes have been made throughout the parks.

Constructed from durable materials designed to endure extreme local conditions, these water sources are situated in the most vulnerable wildlife habitats, despite the logistical challenges of accessing remote jungle areas.

Camera traps have captured images of various species using these waterfowl, including tapirs, pumas, jaguars, deer, margays, and snakes.

These findings offer valuable insights into animal behavior under water stress and demonstrate how scientifically-informed conservation efforts can alleviate the impact of climate change on fragile ecosystems.

https://www.youtube.com/watch?v=bk1lijeo1ue

“During the dry season, many natural water sources completely dry up,” notes Ronnie Garcia Andru, director of the Biology Research Division at the Wildlife Conservation Association’s Guatemala Program.

“This drastically lowers the survival chances for numerous species.”

Initially intended to provide critical relief during periods of drought, monitoring with camera traps has shown that the artificial watering holes are also frequented in the rainy season.

This unexpected trend indicates that not only are some regions experiencing ongoing water shortages, but that these structures are becoming an integral part of the local wildlife’s habitat.

This adaptive maintenance strategy has been developed through collaboration.

“While artificial watering holes are not a permanent fix, they serve as a crucial tool for helping wildlife adapt to increasingly erratic environmental conditions,” Garcia Andru remarked.

“The success of this initiative highlights the significance of collaborative, science-driven approaches in the conservation of the Mayan forests, one of the largest tropical forests in the Americas.”

“As climate patterns continue to evolve, these partnerships will be essential to preserving the remarkable biodiversity of the region for future generations.”

____

This article is derived from a press release provided by the Wildlife Conservation Association.

Source: www.sci.news

Introducing the New England Team Dedicated to Seal Conservation

Block Island, Rhode Island – The enigmatic aquarium animal rescue team is busier than ever.

With binoculars in hand, Program Manager Sarah Curran surveys the coastline, facing an increasing problem on Block Island.

When fishing gear, litter, or balloons entangle a gray seal’s neck, these marine mammals, which can weigh over 800 pounds, may suffer serious injuries or even death as the restraints tighten.

Thus far this year, Connecticut nonprofits have reported 20 tangled gray seals, surpassing the usual count recorded by Mystic each year.

Curran affectionately dubbed one of the seals “anxiety.”

Intertwined stickers.
Mysterious aquarium

NBC News has been granted rare access to follow Mystic’s collaboration with the Atlantic Marine Conservation Association and the Brock Island Maritime Institute, which recently formed.

Curran and her team navigated around a group of seal pups basking at the water’s edge. They skillfully separated the entangled pups and dashed on bright red boards to capture them with precision and speed.

Once a pup was secured, the team worked quickly to attach a tracker for research and freed it from the fishing net constricting its neck.

“We can release stickers today and avoid the need to transport them to the clinic for rehabilitation,” said Curran, who leads the effort. “The sooner you can intervene, the better the chances of recovery.”

This team previously photographed a seal pup stuck with a plastic object in downtown New Haven, Connecticut, in February. The pup, with its big eyes and gentle whine, captured the public’s heart and even received the name “Chappy” through a voting contest.

Unfortunately, Chappy’s story didn’t have a happy ending. In a statement online, Mystic reported that pieces of plastic were found in his stomach, highlighting the dangers that marine debris, particularly plastic, poses to marine life.

Some estimates indicate that plastic pollution claims the lives of over 100,000 marine mammals annually.

“The number of animals interacting with human debris in their early months of life is quite alarming,” Curran stated.

In this ongoing battle, Mystic remains undeterred.

The team celebrated as the seals returned to the sea, now freed from the constraining nets.

“It’s a special moment to give these animals a second chance at life,” Curran remarked. “It’s truly rewarding to witness.”

Source: www.nbcnews.com

The COP16 biodiversity summit resulted in significant setbacks for conservation efforts

Police stand guard in front of a hotel ahead of the United Nations biodiversity conference COP16 to be held in Cali, Colombia on October 19th.

Fernando Vergara/AP/Alamy

Biodiversity loss is a crisis. And it's clearer than ever that the world isn't moving fast enough to solve it. Last weekend's COP16 summit in Cali, Colombia, collapsed in overtime, with too few countries present to agree on a global plan to halt the decline of nature.

“Unfortunately, too many countries and UN officials are working to address our species’ most pressing existential issues without the level of urgency and ambition needed to secure an outcome at COP16. “I came to Cali,” he says. Brian O'Donnell At the environmental advocacy group “Campaign for Nature.”

Signs of the lack of progress were evident from the start of the meeting, with nearly all countries demonstrating how far they have reached ambitious biodiversity targets set at COP15 two years ago, including protecting 30 percent of the planet's land. The deadline to submit a formal plan on how to achieve this was missed. Several more plans were brought forward during the two weeks of the summit, including plans from big countries like India and Argentina, but strategies for most countries have yet to be developed.

As COP16 began, it was clear that the world was not on track to achieve these goals. Since 2020, the area of ​​Earth's land and oceans under formal protection has increased by just 0.5%, according to a UN report released during the summit. This is too slow a rate to protect 30 percent of the planet by the end of the decade.

And their protection is desperately needed. a report A report by the Zoological Society of London and the World Wildlife Fund released ahead of the summit found that vertebrate populations have declined by an average of 73 percent since 1970, and have increased by 4 percentage points since 2022. reportA report presented at a conference by the International Union for Conservation of Nature found that 38 percent of the world's tree species are at risk of extinction.

Many low-income countries said a lack of financial resources prevented them from developing and submitting plans on time, let alone starting implementation. At COP16, high-income countries pledged a total of around $400 million to support these efforts, but funding remains billions of dollars short of the annual target of $20 billion pledged by 2025. .

Negotiations went into overtime early Saturday morning, with no clear plan to close the funding gap and monitor progress toward the goal left unresolved. As delegates left, the number of countries present fell below the minimum required for decision-making, and the meeting was adjourned without reaching a resolution. The topic will be taken up at an interim meeting to be held in Bangkok, Thailand, in 2025.

“Nature is on life support and here in Cali, unless we reach a strong financial compromise, we risk collapse,” he says. Patricia Zurita At Conservation International, a nonprofit environmental organization.

Although COP16's failure to change the direction of fiscal issues disappointed observers, one important agreement was reached at the meeting. It's an agreement on how to collect revenue from products developed using Earth's genetic data. Before the conference is adjourned, each country will require pharmaceutical and other biotech companies that use such “digital sequence information” to donate 0.1% of their revenue or 1% of their profits to the “Kali Fund” We agreed to ask. This fund will be used to protect the biodiversity that is the source of such genetic data.

The fact that the agreement, which took nearly a decade of negotiations and is voluntary and less comprehensive than the African Union and some low-income countries had hoped, means that individual countries and companies This means that it depends greatly on how you respond to the situation. But the United Nations estimates that the fund could raise up to $1 billion a year for biodiversity. “We may be able to get some, but it's nowhere near the scale and speed that is required,” said Pierre du Plessis, a longtime African Union negotiator. Ahead of the meeting, he claimed: new scientist The fund should be bigger.

Indigenous peoples also see a victory ahead of the conference's suspension, with the establishment of formal institutions that will give them a stronger voice in biodiversity negotiations.

However, the overall atmosphere was heavy. “The really disappointing thing about COP16 is that [debates on] “Digital sequence information sucks every last drop of energy and time,” he says. Amber Scholz At the Leibniz Institute DSMZ in Germany.

One reason for the apparent lack of urgency is that the world treats climate change and biodiversity loss as two separate problems. The annual global climate summit attracts more participants and far more attention than the biodiversity negotiations. While 154 people attended last year's climate summit in Dubai, United Arab Emirates, only six leaders attended COP16. This is a problem when the two issues are intertwined. Climate change is one of the main threats to biodiversity, and the ecosystems with the highest biodiversity often also have the greatest ability to store carbon.

“I think the most important thing we need is to change the persistent neglect of biodiversity, especially when compared to climate change,” UN Secretary-General António Guterres said at the summit. mentioned in. “They are all interconnected and cannot be divided.”

topic:

Source: www.newscientist.com

Iberian lynx saved from the brink of extinction thanks to conservation efforts

Things are getting better Iberian Lynx.

About 20 years ago, the pointy-eared wild cat was on the brink of extinction, but as of Thursday, the International Union for Conservation of Nature announced that the species is no longer endangered.

Thanks to successful conservation efforts, the animal, which is native to Spain and Portugal, is now considered almost certainly not threatened, according to the latest IUCN Red List.

A baby Iberian lynx in Doñana National Park, Aznalcázar, Spain, in 2018.
Antonio Pizarro/AP Files

In 2001, there were only 62 mature Iberian lynx left in the Iberian Peninsula. The Iberian lynx is a medium-sized, spotted brown cat with distinctive pointed ears and a pair of whisker-like tufts of facial hair. The extinction of this species is closely linked to the extinction of its main prey, the European rabbit, habitat degradation, and human activities.

Alarm bells were sounded and breeding, reintroduction and conservation projects were launched, as well as efforts to restore habitats such as dense forests, Mediterranean scrub and pastures. Portugal The IUCN said the population was 648 adults, but the most recent count last year found there were more than 2,000 adults and juveniles.

“This huge population increase is a really huge success,” Craig Hilton-Taylor, head of the IUCN Red List Division, told The Associated Press.

Iberian Lynx.
Juan Giribet/VWPics/VWPics via AP

One of the keys to the rabbit population’s recovery has been attention to rabbit populations that were affected by changes in agricultural production, which has led to a steady increase in lynx numbers, Hilton-Taylor said.

“The greatest recovery of this cat species has been achieved through conservation efforts thanks to the dedicated collaboration between public and scientific institutions, NGOs, the private sector and local residents, including local landowners, farmers, game wardens and hunters,” Francisco Javier Salcedo Ortiz, coordinator of the EU-funded LIFE Lynx-Connect project, said in a statement.

IUCN has worked with local communities to raise awareness of the Iberian lynx’s importance to the ecosystem, which has helped reduce animal deaths from poaching and roadkill, and farmers receive compensation if an Iberian lynx kills their livestock, Hilton-Taylor said.

More than 400 Iberian lynx have been reintroduced into parts of Portugal and Spain since 2010 and now live over at least 3,320 square kilometres of land, up from 449 square kilometres in 2005.

Iberian lynx in Doñana National Park, Aznalcázar, Spain, 2019.
Antonio Pizarro/AP Files

“Everything has to be taken into consideration before we release the lynx, and we revise our protocols approximately every four years,” said Ramon Pérez de Ayala, Spain’s species project manager for the World Wildlife Fund (WWF), one of the NGOs involved in the project.

While the latest Red List status offers hope for other species in a similar situation, Hilton-Taylor said the lynx was not out of danger yet.

The biggest uncertainty is what will happen to rabbits, an animal vulnerable to virus outbreaks and other diseases that can be transmitted by livestock.

“We’re also concerned about the issue of climate change and how habitats will respond to it, particularly the increased impact of fires such as we’ve seen in the Mediterranean over the past year or two,” Hilton-Taylor said.

Source: www.nbcnews.com

Utilizing DNA from Polar Bear Snow Tracks to Support Conservation efforts

Researchers have developed a breakthrough method to protect polar bears by analyzing DNA from footprints in the snow. This non-invasive technique can also be applied to other snow-dwelling animals such as lynx and snow leopards, providing a safer and more efficient way to collect data essential to wildlife conservation.

Scientists have discovered a way to capture DNA Observations from snow tracks – a promising non-invasive way to monitor elusive animals like polar bears.

The polar bear is a symbol of the Arctic, an elusive and vulnerable animal. Close monitoring of polar bear populations is critical to polar bear conservation, but polar bears are so difficult to find that critical data about population size and connectivity between those populations is lacking. I am. Scientists have now developed a helpful new tool: DNA analysis using skin cells shed from bear tracks in the snow.

Dr Melanie Lancaster of the World Wildlife Fund’s Global Arctic Program said: ‘Finding polar bears in the Arctic, let alone counting them and understanding how they are coping with climate change, is particularly difficult. “And it’s expensive and time-consuming.” , senior author of the study Frontiers of conservation science.

Innovative forensic techniques in preservation

The scientists were inspired by forensic techniques that can be applied to trace amounts of degraded DNA samples. These techniques eliminate the need to physically capture bears, which can be stressful and dangerous for both bears and humans, and is a concern for some local indigenous communities. Instead, scientists can look at the source of accidentally released DNA: environmental DNA.

A polar bear in Utchagvik, Alaska.Credit: Elizabeth Kruger, World Wildlife Fund

“Many Inuit have expressed concerns about invasive research methods,” said the article’s author, Elizabeth Krueger of the World Wildlife Fund. “People are concerned about the welfare of individual polar bears and the health and safety of those who may later harvest the bears. This is one reason we are so excited about new methods like this. The person collecting the samples does not need to see or even be seen by the polar bear.”

Environmental DNA: a non-invasive tool

A common form of environmental DNA is deposited when animals defecate. However, the quality of DNA is not always sufficient for the individual-level analysis required for preservation. Furthermore, in the case of territorial animals like her other two, seed Scientists tested lynx and snow leopards, and the collection of faeces can affect the animals’ behavior. So the researchers focused on the skin cells in snowy footprints.

“Trucks typically contain fresh cells and the DNA is intact due to the cold ‘storage’ temperatures. “The DNA that passes through the intestine is further degraded, making it more difficult to study,” said lead author Dr Michaela Helström from MIX Research Sweden AB.

Real-world tracking and sampling

The researchers collected snow from individual footprints made by polar bears in Alaska and Eurasian lynx in Sweden in the wild and in captivity. They also collected snow from footprints made by captive snow leopards. Additional substances such as hair, saliva, and mucus were also sampled to ensure that the traces yielded accurate genotypes.

Twenty-four wild polar bear tracks and 44 wild lynx tracks were sampled. The researchers melted and filtered the snow to collect environmental DNA and analyzed the microsatellites. Although the concentration of DNA recovered from footprints collected in the wild was very low, we were able to recover nuclear DNA from 87.5% of wild polar bear footprints and 59.1% of wild lynx footprints. We were able to genotype 13 of the wild polar bear samples and identify 12 different individuals.

They were able to genotype 11% of the lynx footprints, but this percentage increased significantly when scientists examined only footprints sampled by trained personnel. They were able to recover nuclear DNA from 76% of the samples collected by trained personnel and genotype 24% of the samples.

A step-by-step approach

This technology has great potential to inform conservation of these animals, better understand animal populations and behavior, and manage conflicts with humans through accurate animal identification. Although non-invasive sampling has a low success rate, it is easy to collect and can greatly expand sample size.

“We hope this method will be adopted by the polar bear research community as a new way to collect information about polar bears, with the participation of hunters, volunteers, and indigenous communities,” Lancaster said. “We also hope that this method can be extended to other animals that live in snowy environments. We have started by showing that this method works for lynx and snow leopards as well. I did.”

Reference: “Capturing environmental DNA from snow tracks of polar bears, lynx, and snow leopards for individual identification” Michaela Hellström, Elisabeth Kruger, Johan Neslund, Mia Bister, Anna Edlund, Patrick Hernvall, Viktor・Birgerson, Rafael Augusto, Melanie L. Lancaster, October 11, 2023. Frontiers of conservation science.
DOI: 10.3389/fcosc.2023.1250996

Source: scitechdaily.com