Tag Archives: early

Southern Europe saw the arrival of early humans approximately 1.3 million years ago.

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a New Researchpublished in the journal Geoscience Reviewhelps resolve one of the longest-running debates in paleoanthropology: when did early humans arrive in Europe?

Ancient humans. Image courtesy of Ninara / CC BY 2.0.

“chronology Homo “Migration out of Africa has expanded substantially over the past 40 years,” said paleoanthropologist Luis Hibbert of the University of Barcelona and his colleagues.

“In 1982, Homo The Asian volcano has been paleomagnetically dated to 900,000 years ago in Java and 700,000 years ago in Italy, Europe.

“Forty years later, the early Homo Outside of Africa, the South Caucasus dates back 1.8 million years, China 1.7-2.1 million years ago, and Java 1.5-1.3 million years ago.

“In Europe, several sites are found to have layers of paleomagnetic polarity reversal several metres deep, indicating that they are more than 770,000 years old.”

In the study, the authors used magnetostratigraphic dating, a method that uses the state of the Earth's magnetic field at the time the sediments were deposited, to date five paleontological localities in the Orce region of Spain.

“The technique is a relative dating method based on the study of the planet's magnetic pole reversals due to the dynamics of the Earth's interior,” they explained.

“These changes have no particular periodicity, but they are recorded in minerals and it is possible to establish periods from various magnetic events.”

“What's unique about these sites is that they are layered and sit within a very long sedimentary layer, over 80 metres long,” Dr Zibert said.

“Typically these sites are found in caves or within very short geological sequences, so it's not possible to develop long paleomagnetic sequences where you can find the different magnetic reversals.”

Global distribution of humans before 1 million years ago (orange) with major dated sites showing potential dispersal routes. The diagram shows Oldowan sites over 2 million years ago in Africa and over 1 million years ago in Eurasia (black dots). White dots indicate the earliest Acheulean sites in Africa (over 1.5 million years ago) and Eurasia (1 million to 800,000 years ago). The oldest Oldowan and Acheulean tools have been found in East Africa, over 2.5 million years ago and over 1.7 million years ago, respectively. In Asia, the oldest Oldowan and Acheulean tools have been found in the Caucasus (7) at 1.8 million years ago and in the Levantine Corridor (9) at 1.2 million years ago, respectively. In Europe, the oldest Oldowan and associated humans have been found in Spain (1, 2) and are debated to be between 1.6 and 900,000 years ago. Images/Photos Courtesy of: Gibert others., doi: 10.1016/j.earscirev.2024.104855.

The oldest remains at the Orce site, which have no evidence of human activity, date to 1.6 million and 1.35 million years ago, according to the study.

The top three sites containing evidence of early humans are dated 1.32 million years ago (Venta Misena), 1.28 million years ago (Barranco Leon 5), and 1.23 million years ago (Fuente Nueva 3).

These chronologies suggest that the Strait of Gibraltar acted as a filter bridge for African species such as hominins. Theropithecus Oswaldand the early Pleistocene hippopotamus.

“This new dating adds to other evidence and supports European colonization through the Strait of Gibraltar rather than the alternative route back to the Mediterranean via Asia,” the scientists said.

“We also support the hypothesis that they arrived from Gibraltar, as no older evidence has been found elsewhere along the alternative route.”

“Our results show a dating gap between the earliest occupation of Asia, 1.8 million years ago, and the earliest occupation of Europe, 1.3 million years ago. This means that African humans arrived in southwestern Europe more than 500,000 years after they first left Africa around 2 million years ago.”

“These differences in human expansion can be explained by the fact that Europe is isolated from Asia and Africa by difficult-to-surmount biogeographical barriers both to the east (the Bosphorus, the Dardanelles and the Sea of ​​Marmara) and to the west (the Strait of Gibraltar),” Dr. Zibert said.

“When humans arrived in Europe, they had the technology necessary to cross the maritime barrier, just as happened a million years ago on the Indonesian island of Flores.”

“In this sense, the Gibraltar route currently requires crossing a sea channel of up to 14 kilometres, although in the past this distance could have been shorter at certain times due to the tectonically active nature of the region and sea-level changes favourable for migration.”

“We found that African animals were migrating through Gibraltar both 6.2 million years ago and 5.5 million years ago, when the Strait of Gibraltar was very narrow.”

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Lewis Guibert othersMagnetic strata dating of Europe's oldest human remains. Geoscience ReviewPublished online July 2, 2024; doi: 10.1016/j.earscirev.2024.104855

Source: www.sci.news

Webb finds early universe protoglobular cluster

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Astronomers using the NASA/ESA/CSA James Webb Space Telescope have discovered at least five young globular clusters within SPT 0615-JD1 (also known as the Cosmic Gems Arc), a strongly lensed galaxy that existed when the universe was 460 million years old.

These images show the galaxy cluster SPT-CL J0615-5746 (right) and part of this cluster (left), showing two clearly lensed galaxies. The Cosmic Gems arc is shown along with several galaxy clusters. Images courtesy of NASA / ESA / CSA / Webb / L. Bradley, STScI / A. Adamo, Stockholm University / Cosmic Spring Collaboration.

“These galaxies are thought to be the main source of intense radiation that reionized the early universe,” said Dr Angela Adamo, astronomer at Stockholm University and the Oskar Klein Centre.

“What’s special about the Cosmic Gems Ark is that thanks to gravitational lensing, we can actually resolve galaxies down to the parsec scale.”

SPT 0615-JD1 was originally discovered in Hubble Space Telescope images obtained by the RELICS (Reionizing Lensing Cluster Survey) program of the lensing galaxy cluster SPT-CL J0615-5746, located about 7.7 billion light-years away in the constellation of Scorpio.

The Webb telescope will enable Dr Adamo and his colleagues to see where stars are forming and how they are distributed, in a similar way that the Hubble telescope is used to study the local galaxy.

Webb’s observations provide a unique opportunity to study star formation and the internal structure of young galaxies at unprecedented distances.

“The combination of the Webb Telescope’s incredible sensitivity and angular resolution at near-infrared wavelengths, along with gravitational lensing by a large foreground galaxy cluster, made this discovery possible that would not have been possible with any other telescope,” said Dr. Larry Bradley, an astronomer at the Space Telescope Science Institute.

“The surprise and excitement I felt when I first opened the Webb images was overwhelming,” Dr. Adamo said.

“We saw a string of tiny bright dots projected from one side to the other. These cosmic gems are star clusters.”

“Without Webb, we would never have known we were observing star clusters in such a young galaxy.”

Astronomers say the discovery connects different scientific disciplines.

“These results provide direct evidence of the formation of protoglobular clusters in faint galaxies during periods of reionization and help us understand how these galaxies successfully reionized the Universe,” Dr Adamo said.

“This discovery also places important constraints on the formation of globular clusters and their early properties.”

“For example, the high stellar densities found in galaxy clusters provide the first indications of processes occurring within them and give new insights into the possible formation of very massive stars and black hole seeds that are important for the evolution of galaxies.”

In the future, the team hopes to construct a sample of galaxies that can achieve a similar resolution.

“I am convinced that there are more such systems in the early universe waiting to be discovered, which will improve our understanding of early galaxies even further,” said Dr Eros Vanzella, astronomer at the Bologna Observatory for Astrophysics and Space Sciences (INAF).

of Investigation result Published in today’s journal Nature.

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A. Adamo othersA bound star cluster observed in a lensed galaxy 460 million years after the Big Bang. NaturePublished online June 24, 2024, doi: 10.1038/s41586-024-07703-7

Source: www.sci.news

Amazing Discovery: JWST Uncovers Abundance of Supernovae in Early Universe

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Many of the circled objects represent previously unknown supernovae.

Collaboration between NASA, ESA, CSA, STScI and JADES

Astronomers using the James Webb Space Telescope (JWST) have discovered a surprising number of supernovae in the distant universe, including some of the most distant yet seen. Their discoveries increase the number of known supernovae in the early universe by a factor of ten.

The researchers imaged the same small patch of sky twice, in 2022 and 2023, and found 79 new supernovae. “It’s actually very small, about the size of a grain of rice held at arm’s length,” the researchers said. Christa DeCourcy “We’ve spent more than 100 hours on JWST,” said Dr. [observing] I took my time with each image, which gives them a lot of depth.”

Astronomers then compared the two images with each other and with previous photos of the same area taken by the Hubble Space Telescope, looking for bright spots that appear in one image but not the other.

These specks are relatively faint stars that shone brightly before fading in bright supernova explosions. Some of them are candidates for the most distant supernovae ever found, although their distances have yet to be confirmed. And one of them is definitely the most distant one ever seen. This star exploded when the universe was only about 1.8 billion years old.

Such supernovae would have produced the heavy elements that are now widespread throughout the universe, so they would have had lower concentrations of these elements than modern supernovae. “The universe at this early stage was fundamentally different from what has been explored in the past by the Hubble Space Telescope and especially ground-based surveys,” he said. Justin Pierre “This is really new territory that JWST is breaking into,” he said during a presentation at the Space Telescope Science Institute in Maryland, where observations could help shed light on what the first stars were like.

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  • Performer/
  • James Webb Space Telescope

Source: www.newscientist.com

New research indicates that woolly rhinos may have been driven to extinction by early humans

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Extinction of Woolly rhinoceros (Coelodonta Antiquitatis) This species, which lived at the beginning of the Holocene Epoch, remains shrouded in mystery, with conflicting evidence as to its causes and dynamics. A team of paleontologists led by scientists from the University of Adelaide and the University of Copenhagen has used computationally intensive modelling techniques and extensive paleontological and ancient DNA information to uncover why and how this enigmatic species went extinct.

Woolly rhinoceros (Coelodonta Antiquitatis) was once widespread across northern and central Eurasia but became extinct about 10,000 years ago. Image by Mauricio Antón.

The woolly rhinoceros is an iconic member of the giant steppe fauna of central and northern Eurasia, originating from the Tibetan Plateau approximately 2.5 million years ago.

It is a cold-adapted species with thick skin and long fur, and its body size is comparable to that of modern mammals. African white rhinoceros (Ceratotherium simum).

Based on fossil chronology, the woolly rhino is estimated to have become extinct by 13,900 years ago, despite having survived multiple glacial and interglacial cycles during the Pleistocene.

However, recent discovery of woolly rhinoceros DNA in early Holocene deposits suggests a later extinction date of 9,800 years ago. This young dating is subject to debate, but is unlikely to be due to redeposition of DNA.

“Using computer models, fossils and ancient DNA, we have traced the population history of woolly rhinoceros across Eurasia over 52,000 years, at a resolution previously thought impossible,” said Dr Damian Fordham, from the University of Adelaide.

“This suggests that a combination of decreasing temperatures beginning 30,000 years ago and small-scale but continuing hunting by humans caused the woolly rhino's range to shrink southwards, confining it to isolated and rapidly degraded habitat at the end of the last ice age.”

“As the Earth thawed and temperatures rose, woolly rhino populations were unable to colonize key new habitats in northern Eurasia, causing destabilization and collapse, ultimately leading to extinction.”

The new research contradicts previous studies that found humans were not responsible for the woolly rhino's extinction, despite the animal coexisting with humans for tens of thousands of years before its disappearance.

“The demographic responses revealed by our analysis have a much higher resolution than previously captured in genetic studies,” said Professor Eline Lorenzen from the University of Copenhagen.

“This allowed us to pinpoint key interactions between woolly rhinos and humans and document how these have changed over time and space.”

“One of these largely overlooked interactions is persistent, low-level hunting by humans, presumably for food.”

“Humans pose similar environmental threats today,” the researchers said.

“Large animal populations have been forced into fragmented and suboptimal habitats by overhunting and changes in human land use.”

“Of the 61 species of large terrestrial herbivores weighing more than one tonne that lived during the Late Pleistocene, only eight survive today, five of which are rhinos.”

“Our results show how climate change and human activities can lead to the extinction of large animals,” said Professor David Nogus Brabo from the University of Copenhagen.

“This understanding is crucial for developing conservation strategies to protect species currently at risk of extinction, such as vulnerable rhinos in Africa and Asia.”

“Studying past extinctions can provide valuable lessons for conserving Earth's remaining large animals.”

of study Appeared in Proceedings of the National Academy of Sciences.

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Damien A. Fordham others2024. 52,000 years of woolly rhino population dynamics reveal mechanisms of extinction. PNAS 121(24):e2316419121; doi:10.1073/pnas.2316419121

Source: www.sci.news

478-Million-Year-Old Fossil Illuminates the Diversity and Evolution of Early Euchelidae

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Euchericherata A large group of arthropods that includes horseshoe crabs, scorpions, spiders, mites, ticks, and the extinct sea scorpions and snails. Abundant cetapedites The new species of Euchelycerate, which lived in what is now Morocco during the Early Ordovician period 478 million years ago, bridges the gap between modern and Cambrian species.

rebuilding the life of Abundant cetapedites. Image credit: Elissa Sorojsrisom.

“Modern scorpions, spiders, and horseshoe crabs belong to a vast lineage of arthropods that appeared on Earth about 540 million years ago,'' said Lorenzo Lustri, a paleontologist at the University of Lausanne. Ta.

“More precisely, they belong to the subphylum, chelicerates, which includes organisms equipped with pincers used specifically for biting, grasping prey, and injecting venom, and therefore chelicerates ( Euchelicerata+Pycnogonida). But what is the ancestor of this very special group?

“This question has puzzled paleontologists ever since the study of ancient fossils began.”

“Among early arthropods, it has been impossible to identify with certainty which forms share enough similarities with modern species to be considered ancestral.”

“The mystery is further complicated by the dearth of available fossils from the critical period between 505 million and 430 million years ago. This has made genealogical research easier. must.”

Abundant cetapedites. Image credit: Lustri other., doi: 10.1038/s41467-024-48013-w.

Dr. Rustri and his co-authors collected fossils of euchelicerate from the 478-million-year-old Fezouata Shale in Morocco, and found that the modern-day euchelicerate and the Cambrian (505 million-year-old) We identified a new species that binds the eucheris cerate.

with scientific name Abundant cetapeditesthe body length of this species was 0.5-1 cm.

“This animal makes it possible for the first time to trace the entire lineage of Euchelicerates, from the appearance of early arthropods to modern spiders, scorpions and horseshoe crabs,” Dr Rustri said.

“Initially, we just wanted to describe this fossil and give it a name.”

“I had no idea it would hold so many secrets.”

“It was therefore an exciting surprise to discover, after careful observation and analysis, that it also fills an important gap in the evolutionary tree of life.”

“Yet, this fossil has not yet revealed all its secrets,” he added.

“Indeed, some of its anatomical features allow for a deeper understanding of the early evolution of the eucherycerate group and perhaps link other fossil forms to this group, the similarities of which are still hotly debated. It is even possible.”

of result appear in the diary nature communications.

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L. Rustri other. 2024. Late Ordovician syndiphosrines reveal the diversity and evolution of early euchelicerates. Nat Commune 15, 3808; doi: 10.1038/s41467-024-48013-w

Source: www.sci.news

Discovery of a previously unknown Jurassic Shuotheriid species illuminates early mammalian evolution

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In a new study, a team of paleontologists examined the structure of teeth. Feredkodon Chowi aims to better understand the phylogenetic relationships and evolutionary paths of a new species of Xuozalaid mammal that lived in what is now China during the Jurassic period.

rebuilding the life of Feredkodon Chowi (right) and Dianoconodon Yonggi (left). Image credit: Institute of Vertebrate Paleontology and Paleoanthropology, Chinese Academy of Sciences.

Professor Patricia Vickers-Rich, a researcher at Monash University and Museums Victoria, said: “Our study challenges current theory and provides a new perspective on the evolutionary history of mammals.”

“By describing the complex tooth shapes and occlusal patterns, we provide important insights into the phylogenetic relationships and evolutionary trajectory of the family Xenodiaceae, which was largely unknown until its recent discovery in China. ”

Shoeteraid a mammal-like animal from the Jurassic period, has baffled scientists because of its unique dental features.

These creatures have so-called pseudoclaws (basin-like structures) located in front of the triangular teeth of the mandibular molars, and the claws seen in modern therian mammals are similar to the triangular teeth of the lower molars. It is different from the claw-like pattern located at the back.

“This unique tooth pattern hinders our understanding of schootelid relationships and the first steps in the evolution of mammalian species,” Professor Vickersrich said.

Professor Vickers Rich and her colleagues examined the pseudotribosphene tooth of a new Jurassic schiotelid. Feredkodon Chowi represented by two skeletal specimens.

They were able to more completely dissect the tooth structure using a variety of analyses, and the results suggested that the tooth structure of schootherids is very similar to that of docodontans. Ta.

This study suggests that there are no true trigonids present in the basal teeth of Xuozalidae, indicating that they are more closely related to Docodontans than previously thought.

This reassessment of tooth structure not only resolves outstanding interpretations but also triggers a reconsideration of evolutionary connections within mammals.

“In 1982, a single small Jurassic mandible with four teeth was placed at a single point in the mammal family tree,” said Dr Thomas Rich, also from Monash University and Museums Victoria.

“We now have two virtually complete specimens analyzed in different ways, all of which place them in very different positions on the mammal family tree.”

“Additional specimens and different methods suggest different interpretations. Science often works like this.”

Based on new data, the Xuozidae appears to belong to a separate clade, the Docodontiformes, separate from the Auscutolibospheniformes, and are therefore grouped as follows: docodontance.

This finding highlights the importance of pseudotribosphenic characters in elucidating the initial diversification of mammals.

“This study highlights the presence of a huge variety of tooth morphologies in early mammals, demonstrating unique ecomorphological adaptations throughout the evolutionary development of mammals,” Professor Vickersrich said. Ta.

of findings Published in today's diary Nature.

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F. Mao other. The Jurassic family Xenotheliidae represents the earliest dental diversification of mammals. Nature, published online on April 3, 2024. doi: 10.1038/s41586-024-07258-7

Source: www.sci.news

Research suggests smartphone app could aid in early diagnosis of dementia in younger adults

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New data suggests that a smartphone app could aid in detecting the main cause of early-onset dementia in individuals at a high risk of developing it.

Researchers have discovered that cognitive tests conducted through smartphone apps can identify early signs of frontotemporal dementia in those genetically predisposed to the condition, showing comparable sensitivity to traditional medical evaluations.

Frontotemporal dementia is a neurological disorder that typically emerges in middle age, impacting a person’s ability to plan, prioritize, filter distractions, and control impulses as certain brain regions responsible for these functions diminish over time.


Approximately one-third of individuals affected by this disease have a genetic component, underscoring the urgency of early diagnosis and monitoring response to treatments most effective in the disease’s initial stages.

Lead author Adam from the University of California, San Francisco, noted, “Most frontotemporal dementia patients receive a belated diagnosis due to their young age and symptoms being mistaken for mental health issues.”

The use of smartphones as diagnostic tools for Alzheimer’s, Parkinson’s, and Huntington’s diseases has been gaining popularity. Researchers collaborated with a software company to develop an app for assessing cognitive function, gait, balance, movement, and language skills in individuals at high genetic risk for frontotemporal dementia, even before symptoms manifest.

The study published in JAMA Network Open demonstrated the app’s ability to accurately detect dementia and potentially outperform traditional neuropsychological assessments in the early stages of the disease.


While there are no immediate plans for public availability, the app could significantly advance research efforts in understanding and treating frontotemporal dementia.

Over 30 clinical trials are underway or in the pipeline, exploring treatments that may slow disease progression in specific gene carriers. The app could address the challenge of collecting sensitive outcome measures easily, benefitting patients, caregivers, and clinicians.

Stafaroni added, “We believe smartphone-based assessments could facilitate innovative trials for potential treatments, reducing the need for frequent in-person evaluations.”

Ultimately, the app may serve as a tool to monitor treatment efficacy and potentially replace most in-person visits to clinical trial sites.

Source: www.theguardian.com

Ancient Canoe Uncovers Early Advances in Navigation Technology

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More than 7,000 years ago, Neolithic people used technologically sophisticated boats to navigate the Mediterranean Sea, according to a new study.

The 7,300-year-old canoe Marmotta 1 is on display at the Museum of Civilization in Rome. It is a huge dugout canoe made from an oak trunk, approximately 10.43 meters long, 1.15 meters wide at the stern, and 0.85 meters wide at the bow. Depending on the part of the canoe, the height is 65 to 44 cm. Image credit: Gibaja other., doi: 10.1371/journal.pone.0299765.

Many of Europe's most important civilizations were born along the Mediterranean coast.

The Phoenicians, Greeks, Romans, and Carthaginians took advantage of the virtually enclosed sea to move quickly between islands along the coast.

At various times in history, the Mediterranean Sea has been a space of travel and a means of communication.

However, one of the major migration phenomena in history occurred during the Neolithic period, when rural societies began to spread around Europe and North Africa.

The beginning of the Neolithic period is recorded in the Near East around 10,000 BC, but communities from that region gradually occupied the entire Mediterranean Sea around 7500-7000 BC, reaching the coast of Portugal around 5400 BC.

In a new study, Dr. Juan Guibaja and colleagues from Spain's National Research Council dug out a tree from La Marmotta, a Neolithic lakeside village near Rome, Italy, between 5700 and 5100 BC. Five dugout canoes that were built were investigated.

Analysis revealed that the canoe was constructed from four types of wood, which is unusual for similar sites, and incorporated advanced construction techniques such as lateral reinforcement.

Three T-shaped wooden objects are also associated with one canoe, each with a series of holes that may have been used to secure ropes tied to sails or other nautical elements. there is.

These features, together with previous reconstruction experiments, indicate that these are seaworthy vessels, a conclusion supported by the presence of stone tools associated with nearby islands.

“These canoes are exceptional examples of prehistoric vessels, and their construction required a well-organized and specialized workforce, as well as a detailed understanding of structural design and wood properties,” the researchers said. said.

“The similarities between these canoes and modern navigation technology support the idea that many major advances in sailing took place during the early Neolithic period.”

“Direct dating of a Neolithic canoe discovered at La Marmotta reveals it to be the oldest in the Mediterranean and provides valuable insight into Neolithic navigation,” the study said. they added.

“Our research reveals the remarkable technological sophistication of early agricultural and pastoral communities, highlighting their woodworking skills and complex shipbuilding.”

of study Published in an online journal PLoS ONE.

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JF Gibaha other. 2024. The first Neolithic ship in the Mediterranean: the settlement of La Marmotta (Anguillara Sabazia, Lazio, Italy). PLoS ONE 19 (3): e0299765; doi: 10.1371/journal.pone.0299765

Source: www.sci.news

When will the current Bitcoin bull run peak based on its early characteristics? – Blockchain News, Opinion, TV, Jobs

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Mateo Greco, Research Analyst, Listed Digital Assets and FinTech Investment Business Finekia International (CSE:FNQ).

Bitcoin (BTC) ended the week at around $68,400, down just 0.8% from the previous week’s closing price of around $69,000. Throughout the week, BTC showed significant volatility, with a price range of 13.4%. The week started off strong with BTC surging to $72,000 on Monday. It then peaked above $73,000 on both Wednesday and Thursday, before reaching an all-time high of nearly $73,800 on Thursday.

Also on Thursday, BTC plummeted to $68,000 before rebounding to close around $71,400. Selling pressure continued on Friday and Saturday, with BTC falling to $64,700 before closing near $65,300 on Saturday. However, positive momentum returned on Sunday, nearly reversing weekly losses and closing at around $68,400.

Despite the volatility and price changes, the past week demonstrated continued strong momentum for the BTC Spot ETF, with net inflows recorded on every trading day. Net inflows for the week exceeded $2.5 billion, with net inflows exceeding $1 billion on Tuesday alone. Cumulative net inflows since its inception are currently approximately $12.2 billion.

BTC spot ETF trading volume is also on the rise, with total trading volume reaching $141.7 billion since inception, including around $28 billion in trades last week. This took his daily trading volume past his $5.5 billion mark last week, and his average daily trading volume has increased since its inception, now sitting at around $3.15 billion.

These numbers confirm that investment momentum from traditional finance to the digital asset space continues. Despite BTC price stabilization last week, demand is primarily coming from ETFs, while native digital asset investors are more active on the short side.

This trend is noticeable in the decline in BTC held by long-term holders, which refers to BTC that has not moved for at least 155 days. At the beginning of 2024, this supply was approximately 16.3 million BTC, but has gradually decreased and currently stands at approximately 15.1 million BTC. While this shift reflects traditional investors driving purchasing activity through ETFs, native digital asset investors who accumulated during the downtrend in 2022 and 2023 are now seeing higher profit-taking rates. The supply of long-term holders is decreasing.

Such behavior is characteristic of early bull phases, when long-term holders distribute assets to new investors. Analyzing past cycles, if the current market is trending up, this pattern is likely to continue until supply from long-term holders matches demand from new investors, which typically occurs at the peak of the cycle. coincides with the beginning of the downtrend phase.

Notably, BTC’s halving is approximately 1 month later, whereas previous cycles’ peaks have historically been 6 to 12 months later. If past patterns repeat, the peak of the current cycle could occur in late 2024 or early 2025.

Source: the-blockchain.com

Innovative Wearable Device Identifies Early Signs of Breast Cancer

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The World Health Organization reported that in 2020, 2.3 million women worldwide were diagnosed with breast cancer. American Cancer Society states that early diagnosis of breast cancer leads to a 100% survival rate. During the initial diagnosis, images or scans of breast tissue are examined by the doctor to detect abnormalities.

Doctors commonly use ultrasound devices to diagnose breast cancer using sound waves. Ultrasound for diagnosing breast cancer. Scientists have identified limitations of ultrasound in the past, such as the need for proper skills and training, poor contact with skin during scanning, and maintenance challenges of large ultrasound machines in hospitals.

To address these limitations, a group of researchers developed a wearable, portable, and affordable device called cUSBr-Patch, which stands for Compatible Ultrasonic Chest Patch. To create this wearable patch, they used a 3D printer to design a honeycomb-shaped patch with holes that can be attached to a soft fabric bra.

Scientists attached a small scanning device to the patch that uses sound waves to acquire medical images similar to an ultrasound machine. This device, called phased array transducer, uses piezoelectric material and differs from traditional hospital ultrasound scanners, producing clear and high-resolution images.

The cUSBr-Patch is attached to a bra with magnets and allows the patch to directly touch the skin for scanning. A small tracker on the phased array transducer is moved and rotated using a handle to capture images of the entire breast.

Researchers tested cUSBr-Patch on female patients with breast abnormalities, scanning both breasts in six different locations using the phased array transducer connected to the patch. Computer programs were then used to generate images similar to those from standard hospital ultrasound machines.

The researchers concluded that cUSBr-Patch can detect breast cancer at a level comparable to traditional hospital ultrasound equipment. They are working on a smaller version of the device, aiming to make it accessible for home use by high-risk individuals and populations without regular testing facilities to improve breast cancer survival rates significantly.


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Source: sciworthy.com

Early humans may have colonized Ukraine as the first part of Europe

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Korolevo Quarry in Ukraine, one of the oldest human remains in Europe

Roman Galba

Molecular dating reveals that an area in Ukraine was occupied by humans 1.4 million years ago, making it one of the oldest human remains in Europe, and possibly the oldest.

The ruins, located in Korolevo in western Ukraine, have been studied since the 1970s. Numerous stone tools were found buried in layers of sediment next to outcrops of volcanic rock suitable for tool making.

“It was like a magnet that drew people to it, and they were camping nearby,” he says. Roman Galba At the Czech Academy of Sciences in Prague.

No bones have been found because the soil was too acidic to preserve bones, but hominins homo erectusa species that evolved about 2 million years ago and spread from Africa to Europe and Asia.

It is clear that early humans were present at the Korolevo sites repeatedly over hundreds of thousands of years, but we do not know exactly when they were present. But Garba's team has now used a technique called cosmogenic nuclide dating to date the oldest layer containing the tools to 1.4 million years ago.

This method relies on cosmic rays that are energetic enough to split atomic nuclei and create unusual isotopes. However, these cosmic rays do not penetrate deeply into solid objects, so these isotopes form only in exposed areas.

When an object is buried, the radioactive isotopes produced by cosmic rays decay into other isotopes, making it possible to determine when the object was buried.

Another early human site in Dmanisi, Georgia, is estimated to be 1.7 million years old, and other sites in France and Spain are about 1.2 million years old. This suggests that early humans migrated from Africa through Georgia into Ukraine and then west to other parts of Europe, Galba said, although some crossed the Bosphorus Strait in Turkey. There is a possibility that it was.

Some humans are crossed the Strait of Gibraltar It arrived in Spain when sea levels were lower than it is now, and then migrated east to other parts of Europe, but there is no evidence to support this, Galba said.

While parts of Georgia are geographically in Europe and the entire country is politically considered part of Europe, the Dmanisi site is geographically located in Asia, Garba said. As such, he and his team consider Korolevo to be the oldest reliably dated human site in Europe.

“Korolevo is, to our knowledge, the oldest confirmed human presence in Europe,” the paper says.

“I agree that the new age estimates are important, and they support the idea of ​​an early east-west dispersal,” he says. chris stringer At the Natural History Museum in London.

But this was already evident from four other sites in Western Europe. It is estimated that it is already about 1.4 million years old.he says.

Garba said these other sites may be just as old; their relationship is questionable. “We're not sure about those,” he says. “It's not safe or robust.”

“With all due respect, I disagree with that,” Stringer said.

topic:

  • archeology/
  • ancient humans

Source: www.newscientist.com

New Study Suggests Photons from Dwarf Galaxies Helped Reionize the Early Universe

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Reionization of the universe happened about 500 million to 900 million years after the Big Bang. This represents the transformation of neutral hydrogen into an ionized gas and marks the end of the “Dark Ages” in the history of the universe. Currently, astronomers using the NASA/ESA/CSA James Webb Space Telescope have obtained spectra of eight ultrafaint dwarf galaxies that existed less than a billion years after the Big Bang. Their observations could help settle long-standing scientific debates about the driving force of reionization and could also be essential to understanding the formation of the first galaxies.

Astronomers estimate that 50,000 near-infrared sources are represented in the Webb image of galaxy cluster Abel 2744. Image credits: NASA / ESA / CSA / I. Labbe, Swinburne Institute of Technology / R. Bezanson, University of Pittsburgh / A. Pagan, STScI.

There is still much we don’t understand about the period in the early history of the universe known as the Era of Reionization.

It was a time of darkness, without stars or galaxies, and filled with a thick fog of hydrogen gas, until the first stars ionized the surrounding gas and light began to pass through.

Astronomers have spent decades trying to identify sources that emit radiation powerful enough to gradually remove this hydrogen fog that blanketed the early universe.

“Our discovery reveals the important role played by ultrafaint galaxies in the evolution of the early universe,” said astronomer Dr. Irina Chemelinska from the Paris Institute of Astrophysics.

“They produce ionizing photons that convert neutral hydrogen into ionized plasma during the reionization of the universe.”

“This highlights the importance of understanding low-mass galaxies in shaping the history of the universe.”

“These cosmic power plants collectively emit more than enough energy to accomplish their work,” said Dr. Hakim Atek, also of the Paris Institute of Astrophysics.

“Despite their small size, these low-mass galaxies produce large amounts of energetic radiation, and their abundance during this period is so great that their collective impact alters the state of the entire universe can do.”

In the study, astronomers captured and analyzed the spectra of eight very faint galaxies magnified by the lensing star cluster Abel 2744.

They found that these galaxies emit large amounts of ultraviolet light, at levels four times higher than previously thought.

This means that most of the photons that reionized the Universe likely came from these dwarf galaxies.

“With the web, we have stepped into uncharted territory,” said Dr. Themiya Nanayakkara, an astronomer at Swinburne University of Technology.

“Our study reveals more provocative questions that must be answered in efforts to chart the evolutionary history of our beginnings.”

of result It was published in the magazine Nature.

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H. Atek other. 2024. Most of the photons that reionized the universe came from dwarf galaxies. Nature 626, 975-978; doi: 10.1038/s41586-024-07043-6

Source: www.sci.news

Satoshi Nakamoto, the founder of Bitcoin, refutes claims of early climate change worries

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Bitcoin was created by Satoshi Nakamoto

Damian Ravaso/Alamy

Bitcoin’s mysterious founder Satoshi Nakamoto dismissed early concerns about the cryptocurrency’s potential to consume large amounts of electricity and contribute to carbon emissions, according to newly released emails.

The true identity of Bitcoin’s creator was never revealed, but after Bitcoin’s creation in January 2009, Nakamoto (a pseudonym) remained active in online forums and emails until late 2010, after which he was removed from the project and stopped communicating with him. .

…

Source: www.newscientist.com

Early Earth conditions could have supported the production of essential life chemicals

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Chemical reactions in volcanic pools may have contributed to the birth of life on Earth

Michael S. Nolan/Alamy

One of the most important molecules in living organisms is synthesized from scratch under everyday conditions. The discovery suggests that this chemical formed naturally early in Earth's history and may have played a role in the origin of life.

The substance in question is called pantetheine. It is not a well-known name at the DNA or protein level. However, pantetheine is an important component of a larger molecule called pantetheine. acetyl coenzyme A, A “cofactor” that helps enzymes work.

“Coenzyme A is present in every organism ever sequenced,” he says. Matthew Powner At University College London.

Powner has spent most of his career discovering ways to make biomolecules from simple chemicals in a way that can occur naturally. Over the past decade, he has shown that: aminonitrile can be used to make nucleotide – the building blocks of DNA – and peptide, Short version of protein.

His team has now shown that aminonitrile can be used to make pantetheine in a series of reactions starting with simple chemicals like formaldehyde. This was done in water, often at such dilute concentrations that the reaction mixture appeared like clear water. The team sometimes used heat to speed up their work, but otherwise did not need to intervene once the reaction started.

“We just put everything in one pot. We literally just throw everything in, we don't change anything, we don't do anything, and we have a 60% yield of product,” Powner says.

Acetyl coenzyme A is involved in the synthesis of several biologically important chemicals. Some of the oldest microbial groups use processes involving microorganisms to obtain carbon from the environment.

Importantly, pantetheine is the active portion of the acetyl-coenzyme A molecule. No more than one bit is “essential to its functionality,” Powner says.

This type of cofactor is present in all living organisms.They are described as follows Origin of life and remnants of early evolution.

“Obtaining key organic biological cofactors from scratch,” he says, is impressive, “not to mention one of such centrally important ones.” Zachary Adam from the University of Wisconsin-Madison was not involved in the study.

For Adam, the importance of this research extends beyond pantetheine and acetyl coenzyme A. “They report this particular part of the cofactor, but intermediates have been shown to be important as well,” he says. Other chemicals produced in the process have been shown to aid in the production of other biomolecules. “They're building a network of compounds.”

Many ideas about the origin of life have assumed that a small set of biomolecules formed long before other molecules. For example, the “RNA world” hypothesis states that first life was made solely of RNA, and other chemicals such as proteins and lipids were added after RNA was able to make them. .

Powner is one of several researchers pushing for an alternative scenario in which many important molecules form early and interact from the beginning. “These products can all be products of the same chemical reaction,” he says. Rather than starting with just RNA, or just peptides, “it might be easier to make them all together, so the chemical reactions they perform are integrated from the original state.”

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  • origin of life

Source: www.newscientist.com

Starting Drug Treatment Early Improves Outcomes for Crohn’s Disease Patients

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Crohn’s disease can cause abdominal pain, diarrhea, and weight loss

Jacob Wackerhausen/iStockphoto/Getty Images/www.peopleimages.com

A one-year study of 386 people found that receiving advanced treatment soon after diagnosis of Crohn’s disease improves outcomes for patients.

This disease is a lifelong inflammatory bowel disease; impact millions of peopleIn the world. Symptoms include abdominal pain, diarrhea, fatigue, and weight loss.

“These symptoms have a huge impact on people’s quality of life, education, relationships, and ability to work,” he says. Miles Parks at Cambridge University. “While there is no cure, there are ways to reduce some of these negative outcomes.”

Treatment often includes dietary changes, immunosuppressants, and steroids. In the UK, a drug called infliximab (an antibody that targets a specific protein in the body that is thought to contribute to intestinal inflammation) is given to people who regularly experience flare-ups of Crohn’s disease, or other mild symptoms. It can be prescribed to people who are not responding to. Treatment.

“This is a ‘step-up’ approach where treatment is progressively escalated in a reactive manner as the disease returns,” he says. Nurlaminnuralso at the University of Cambridge.

To see what happens if this more powerful treatment is used as early as possible, Parkes and Noor et al. studied 386 newly diagnosed Crohn’s disease patients aged 16 to 80 in the UK. Recruited people.

They were divided into two groups. One patient received infliximab immediately regardless of symptoms, and the other was treated with other Crohn’s disease drugs. If symptoms persist or continue to worsen, participants in the second group will also be prescribed infliximab, in line with a “step-up” approach.

After one year, 80 percent of patients who initially received infliximab had their symptoms under control over time, compared with only 15 percent of those who did not receive treatment immediately.

Additionally, only 0.5% of people in the group who received infliximab immediately required abdominal surgery for Crohn’s disease, compared to 4.5% in the second group.

The results of this study suggest that giving patients with Crohn’s disease intensive treatment as soon as they are diagnosed may be more effective in improving their lives, Dr. Noor said.

Parks said the extra money spent on medication would be balanced out by not having to pay for subsequent scans, colonoscopies and surgeries for people with repeated relapses.

“People with Crohn’s disease don’t want to be hospitalized or undergo surgery. They want to go out into the outside world and live their lives. Anything that speeds the path to remission. It can only be a good thing,” says Ruth Wakeman of the charity Crohn’s & Colitis UK.

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Source: www.newscientist.com

New research indicates that early Mars experienced both tectonic and volcanic activity.

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Mars' relatively well-preserved ancient crust provides a natural window into early planetary evolution not visible on Earth. Mars has generally been thought to be a monolithic basaltic planet, but recent evidence suggests that magmatic evolution leading to a felsic crust may have occurred sporadically. A new study shows multiple lines of evidence for diverse volcanic activity and complex volcanic tectonics in Mars' southern highlands in and around the Eridanian basin 3.5 to 4 billion years ago.

Topographic map of the Eridanian region of Mars. The volcanic structure described by Michalski et al. Classified by morphology and morphometrics. Image credit: Michalski other., doi: 10.1038/s41550-023-02191-7.

In contrast to Earth, Mars today has little volcanic or tectonic activity.

Additionally, nearly half of Earth's surface is more than 3.5 billion years old, and since then it has undergone extensive tectonic recycling (a phenomenon typically caused by Earth-like tectonic movements, in which surface material is recycled into the mantle). This shows that there is no such phenomenon.

Recent discoveries suggest that this is not always the case, but geological activity during the first billions of years after Mars' formation is still unknown.

“Geological exploration of other rocky planets provides clues to early crustal evolution and volcanic tectonic processes,” said Dr. Joseph Michalski of the University of Hong Kong. “This is an example of an equivalent Earth system with a changing composition.”

“Looking through the lens of different gravitational fields, bulk planetary compositions, and heat flows allows us to test models of crustal resurfacing and discover the steps that led to plate tectonics and other forms of crustal recycling.” It will be possible to do so.”

“Mars represents a particularly valuable piece of the puzzle in this regard.”

The authors studied the morphology and mineralogy of the Eridanian region in Mars' southern hemisphere.

They analyzed remote sensing data from a variety of orbiting satellites, including NASA's Mars Global Surveyor, Mars Odyssey, and Mars Reconnaissance Orbiter.

The Eridanian region contains the most powerful crustal remains of Mars' ancient magnetic field and various traces of volcanic activity.

The researchers identified 63 examples of four different types of volcanoes (volcanic domes, stratovolcanoes, pyroclastic shields, and caldera complexes), and there are likely hundreds more in the Eridanian region alone. , these are probably the remnants of a period of active geological activity about 3.5 billion years ago.

This set of observations is consistent with the existence of early Martian tectonic cycles driven by vertical tectonics, a type of tectonic process precursor to full plate tectonics on Earth.

Such diverse volcanic structures may be more widespread on ancient Mars than previously thought.

“The observed remnants of this activity may be the closest analog on Earth to the proposed hydrothermal origin of life scenario for Earth,” the scientists said.

Their paper Published in an online journal today natural astronomy.

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JR Michalski other. Diverse volcanic activity and crustal circulation on early Mars. Nat Astron, published online on February 12, 2024. doi: 10.1038/s41550-023-02191-7

Source: www.sci.news

Paleontologists Say Early Dinosaurs Thrived and Survived Due to Advances in Motor Skills

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Early dinosaurs were faster and more dynamic than their competitors, according to a study led by University of Bristol researcher Amy Shipley.

By adopting more diverse limb morphologies and styles, dinosaurs may have been able to occupy more terrestrial habitats and greatly diversify extinction events. Image credit: Sergey Krasovskiy.

In their study, Shipley and colleagues compared the limb proportions of a wide range of Triassic reptiles. The Triassic period is the period from 252 million years ago, when dinosaurs first appeared and became famous, to 201 million years ago.

They determined which of these ancient beasts were quadrupedal (quadrupedal) or bipedal (bipedal), and also examined the cursority index, a measure of running ability.

Researchers found that not only were dinosaurs and their relatives bipedal from the beginning, meaning they had limbs adapted for running, but they also We found that it showed a much wider range of running styles. pseudostia.

Pseudonesians also included the ancestors of modern crocodiles. Although there were some small bipedal animals that ate insects, most were medium to large carnivores or herbivores, and they were diverse throughout the Triassic.

The authors believe that dinosaurs and their relatives bird metatarsal maintained a higher range of motor modes throughout this period.

“When the crisis hit 233 million years ago, the dinosaurs won,” Shipley said.

“At that time, the climate changed from wet to dry and there was severe pressure on food.”

“For some reason, dinosaurs, which had been living in small numbers for 20 million years, appeared, but no pseudo-dinosaurs appeared.”

“Like many reptiles and birds today, early dinosaurs may have been good at conserving water.”

“However, our evidence shows that their high adaptability during walking and running played an important role.”

“After the mass extinction at the end of the Triassic period, dinosaurs expanded again,” added Professor Mike Benton from the University of Bristol.

“With the exception of the crocodile ancestors, most of the pseudodinosaurs went extinct in mass extinctions, and we found that these surviving dinosaurs once again expanded their range and took over many of the niches that had been vacated.”

“When we looked at the rate of evolution, we found that dinosaurs were not actually evolving particularly rapidly,” said co-author Dr Armin Elsler, a researcher at the University of Bristol.

“This was a surprise because we expected to see rapid evolution in ornithopods and slower evolution in pseudopods.”

“What this means is that while dinosaur locomotion style was advantageous for dinosaurs, it was not the driving force behind intense evolutionary selection.”

“In other words, when the crisis happened, they were in a better position to take advantage of the opportunities after the crisis.”

“We always think of dinosaurs as large, mobile animals,” says co-author Dr Tom Stubbs, also from the University of Bristol.

“This reminds us that dinosaurs actually started out as nifty little insect-eaters.”

“The first dinosaurs were only a meter long and walked bipedally with their legs raised high. Their leg posture meant they could move quickly and capture prey while fleeing from larger predators. I meant it.”

“And of course, dinosaurs' postural diversity and focus on fast running mean that dinosaurs could diversify given the opportunity,” said co-author Suresh Singh, also from the University of Bristol. the doctor said.

“After the mass extinction at the end of the Triassic period, truly gigantic dinosaurs emerged, over 10 meters long, some with armor, many quadrupedal, but many still bipedal, like their ancestors. Walking.”

“Their diversity of posture and gait means they are highly adaptable, and this ensured their great success for a long time on Earth.”

of study It was published in the magazine Royal Society Open Science.

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Amy E. Shipley other. 2024. Archosauromorph migration and early Mesozoic success. R. Soc. Open Science 11(2):231495; doi: 10.1098/rsos.231495

Source: www.sci.news

Unique Crown Shapes of Early Carboniferous Tree Species

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Sanphodiacaulis densifolia is an extinct tree species that existed in what is now New Brunswick, Canada, between 359 and 347 million years ago (Carboniferous period). The structure consisted of an unbranched 16 cm diameter trunk and compound leaves arranged in a 13 cm spiral and compressed to a vertical trunk length of 14 cm. The compound leaves in the upper 0.75 m of the trunk were over 1.75 m long, with preserved alternating secondary collaterals starting 0.5 m from the trunk. In the lower region of the trunk there were only persistent leaf bases. Sanphodiacaulis densifolia shows that the early Carboniferous vegetation was more complex than expected, indicating that this was an experimental, perhaps transitional, period of diverse growth structures.

Sanphodiacaulis densifolia. Image credit: Tim Stonecipher.

Trees first appeared during the Middle Devonian period (393 to 383 million years ago), but modern woody plants did not appear until about 10 million years later.

Evidence for dendritic structures (tree-like structures) is primarily based on mud moldings, sand moldings, or calcified stumps, or extensive root structures in fossilized soils.

Under unique preservation conditions, these early trees fossilized with roots and crown structures attached to their trunks.

“The method is Sanphodiacaulis densifolia “It has very long leaves around its slender trunk, and it's amazing how many leaves there are on such a short trunk,” said Dr. Robert Gastaldo, a paleontologist at Colby College. he said.

“The morphology of these 350-million-year-old trees looks like ferns or palms, even though palms arose 300 million years ago.”

“However, the functional leaves of ferns and palm trees are clustered at the top and are relatively few in number.”

“in contrast, Sanphodiacaulis densifolia More than 250 leaves have been preserved around the trunk, with each partially preserved leaf extending 1.75 meters from the trunk. ”

“We estimate that each leaf grew at least another meter before it finished.”

“This means that ‘bottlebrush’ had a dense canopy of leaves that were not woody and spread for at least 5.5 meters around a trunk that was only 16 cm in diameter. Amazing to say the least. .”

Sanphodiacaulis densifolia It has compound leaves arranged in a spiral.Image credit: Gastaldo other., doi: 10.1016/j.cub.2024.01.011.

Dr. Gastaldo and his colleagues examined five fossil specimens. Sanphodiacaulis densifolia.

The fossil was excavated from the Sanford Quarry, part of the Albert Formation in New Brunswick, Canada.

“These fossils were preserved when an earthquake destroyed trees and other vegetation along the edge of a rift lake,” Gastaldo said.

“The first fossil wood was unearthed from a quarry about seven years ago, but it contained only one partial sample.”

“It took several years to find four other specimens of the same plant in close spatial proximity.”

“One of the specimens reveals how the leaves separate from the top of the tree, which makes this tree quite unique.”

“This is one of the few preserved trunks with crown leaves still attached in a fossil record spanning more than 400 million years.”

Actual and reconstructed heights and biostratigraphic ranges of Pennsylvanian trees from the Middle Devonian. Image credit: Gastaldo et al., doi: 10.1016/j.cub.2024.01.011.

Sanphodiacaulis densifolia It probably relied on its unusual growth form to maximize the amount of light it could capture and reduce competition with other plants above ground.

This discovery provides important insights into the evolution of plants and arboreal growth, that is, plants that grow to the height of a tree, or at least 4.5 m, at maturity.

They also remind us that throughout the history of life on Earth, there have been trees that look like nothing we've ever seen before.

“We all have a mental concept of what a tree looks like, depending on where we live on the planet, and we all have a vision of something familiar,” Dr. Gastaldo said. Ta.

“The fossils we report are unique and represent some of the strangest growth forms in the history of life.”

“This is an evolutionary experiment during a period of forest plant biodiversity, and it appears to be a short-lived form.”

“The history of life on land consists of plants and animals that are different from those that live today,” he added.

“The evolutionary mechanisms that operated in the distant past allowed organisms to survive for long periods of time, but their shape, morphology, growth structure, and life history followed different trajectories and strategies.”

“Rare and unusual fossils like the New Brunswick tree are just a few examples of failed experiments that have colonized our planet.”

a paper The survey results were published in a magazine current biology.

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Robert A. Gastaldo other. A mysterious fossil plant with a three-dimensional tree-like growth structure from the earliest Carboniferous period in New Brunswick, Canada. current biology, published online on February 2, 2024. doi: 10.1016/j.cub.2024.01.011

Source: www.sci.news

Early Arrival of Humans in China Surprises Researchers by Thousands of Years

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The first members of our species to reach China may have entered this region from the north

Esteban de Armas / Alamy

Modern humans lived in what is now China by 45,000 years ago. This discovery means our species arrived in this region thousands of years earlier than commonly thought, probably via a northern route through present-day Siberia and Mongolia.

A team co-led by Francesco d'Errico Researchers from the University of Bordeaux in France reexamined an archaeological site in northern China called Shiyu. Originally, he was excavated in 1963 during the turbulent period of China's Cultural Revolution. “It couldn't have been a better time to find such an important site,” D'Errico says.

Shiyu is an outdoor site located in a river gorge. There, 30 meters deep, sand and other sediments were deposited, which the first excavators divided into four horizontal layers, from the bottom of which the second layer contained human It was found that there was evidence of residence in

Excavators discovered more than 15,000 stone artifacts and thousands of animal bones. There was also part of a hominin skull, which anthropologist Wu Lukang identified as a modern human.homo sapiens).

Some of the artifacts were later transferred to the Institute of Vertebrate Paleontology and Paleoanthropology in Beijing. However, those left behind at the local facility were lost, including the hominin bones. “We own maybe 10 percent of the stone tools,” D'Errico says.

D'Errico and his colleagues re-excavated Shiyu to determine its age. They dated 15 sediment samples using a technique called photostimulated luminescence and carbon-dated 10 animal bones and teeth. The hominid layer is approximately 44,600 years old.

D'Errico believes the excavator was “knowledgeable” and correctly identified the skull.

The Shuyu tribe is probably homo sapienssay Alina Katzenovic from the Institute of Archeology and Ethnology in Novosibirsk, Russia, was not involved in the study.

The new study therefore suggests that modern humans arrived in northern China about 45,000 years ago. This would postpone the arrival of our species to China by about 5,000 years.Derico claims to be the next oldest homo sapiens China's site Tengen Cave 40,000 years ago.

Some researchers argue that our species may have arrived earlier than that, up to 260,000 years ago. However, D'Errico points out that researchers: criticized much of the evidence As for the presence of such early humans in this region.

Humans probably entered Asia from Africa and spread through multiple routes, Katzenovich said. They not only explored the tropical southern regions of Asia, but also headed further north. Katzenovich says there are signs of modern human presence in the area. Obi Rakhmat Cave Uzbekistan 48,800 years ago. Perhaps our species reached Shiyu and then China via this route. north route.

When modern humans reached new areas, they encountered hominids that were already living there, such as Neanderthals and Denisovans further east. Genetic evidence shows that we interbred with them. There may also have been cultural exchanges, and the Shiyu artifacts also include what appear to be more ancient human tools.

There is also evidence of long-distance contact. The Shiyu team identified four fragments of obsidian, a volcanic glass. They were able to track them as far as 800 and 1000 kilometers northeast of Shiyu. D'Errico said it was unlikely that the residents traveled this distance themselves, so they were probably part of the group's network. In line with this, Kazenovich said some of Shiyu's artifacts resemble items found as far east as Korea.

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Source: www.newscientist.com

Discovery of new Tyrannosaurus species through early fossil findings

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Artist's impression of Tyrannosaurus macraensis, a relative of Tyrannosaurus rex

sergei krasinski

A portion of a dinosaur skull discovered 40 years ago has been identified as a new species of dinosaur. tyrannosaurusand is probably the closest relative tyrannosaurus rex. The study adds a new twist to the long-standing debate about how many different tyrannosaurus species there were, and could help shed light on how the iconic predator evolved.

tyrannosaurus They first appeared in North America about 68 million years ago, 2 million years before the mass extinction event that wiped out most dinosaurs. Paleontologists are puzzled about the origins of this carnivore. Some suggest that it is an ancestor of tyrannosaurus Some people walked across land bridges from prehistoric Asia, while others traced their origins to southern North America.

Anthony Fiorillo Researchers from the New Mexico Museum of Natural History and Science reviewed fossils in the museum's collection that were discovered in a rock formation known as the McRae Formation in western New Mexico.

Skulls were originally classified as: tyrannosaurus, Fiorillo and his colleagues noticed differences in the bones.They proposed that this specimen represented an older species, which they named Tyrannosaurus macraiensis in reference to the rock in which it was found.

They estimated that the dinosaur was about 12 meters long, comparable in size to an aosaurus. Tyrannosaurus, However, it lived about 4 million years ago.

difference between tyrannosaurus and T. macraensis It would have been relatively subtle.on the other hand tyrannosaurus He had a prominent ridge on his eyebrow, and a bone-crushingly wide jaw with the same ridge. T. macraensis The body is less developed and the skull is thinner, Fiorillo said.

Jawbone identified as new species of Tyrannosaurus

nick longrich

Other recent studies have proposed that several species exist. tyrannosaurus And the so-called tyrannosaurus Fossils need to be reallocated. However, such proposals are controversial and are mostly rejected by dinosaur paleontologists. The new study is likely to spark further debate about that number. tyrannosaurus The species was found in North America.

“I hesitate to consider Tyrannosaurus macraiensis as different from tyrannosaurus rex” Jared Voris at the University of Calgary, Canada. He points out that many of the anatomical features that make the new species unique are also present in the specimen. tyrannosaurus.

Regardless of species assignment, the existence of such large tyrannosaurs millions of years ago is tyrannosaurus This suggests that southwestern North America was an important center of dinosaur evolution. “The age range of the proposed specimen is unique and requires further study,” Voris said. That's because it could outline a clearer picture of dinosaur evolution during the last few million years of the Cretaceous.

The New Mexico tyrannosaurus was discovered in the same rock as a giant horned dinosaur, an anthropomorphic duck-billed dinosaur, and a long-necked herbivore up to 30 meters long. Fiorillo and his colleagues tyrannosaurus It may have evolved to its gigantic size to prey on these large herbivores, and later spread north as the last “tyrant lizard” to stalk the planet.

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Source: www.newscientist.com

First American lunar lander in over five decades blasts off towards the moon, but faces early technical issues

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Astrobotic said the cause of the failure was likely a propulsion failure, adding that a further update would be issued once more data is acquired and analyzed.

Peregrine’s mission represents a new chapter in the commercial space industry, launching private companies into the space race and delivering to NASA and other customers.

The Pittsburgh-based company First private company to succeed in landing This is something only four countries have achieved on the moon. A Houston-based company also has a lander ready to fly and is expected to take a more direct route to the moon.

NASA provided both companies with significant funding to build and fly their own lunar landers. The space agency hopes the privately owned lander will scout the site before astronauts arrive, while also providing technical and scientific experiments for NASA and benefiting other customers. Astrobotic’s Peregrine lander contract: $108 million.

During its first flight, the Peregrine lander carried five NASA instruments. Following the technical anomaly, NASA said it would learn from the situation.

“Each success and setback is an opportunity for us to learn and grow,” Joel Kearns, deputy assistant administrator for exploration at NASA’s Science Mission Directorate, said in a statement Monday. “We will use these lessons to advance our efforts to advance science, exploration, and commercial development of the Moon.”

The last time the United States launched a moon landing mission was in December 1972. Apollo 17’s Gene Cernan was the last human to set foot on the moon as mission commander, and Harrison Schmidt was the 12th astronaut to walk on the moon. , concluded an era that continued to be the pinnacle of NASA.

The space agency’s new Artemis mission, named after Apollo’s twin sister in Greek mythology, aims to return astronauts to the moon’s surface within the next few years. first, Flight around the moon by four astronautsProbably by the end of the year.

Highlighting Monday’s moonshot was the long-delayed initial test flight of the Vulcan rocket from Cape Canaveral Space Force Station. The 202-foot (61-meter) rocket is essentially an upgraded version of ULA’s highly successful flagship Atlas V, which will be phased out along with the company’s Delta IV. Jeff Bezos’ rocket company Blue Origin provided his two main engines for the Vulcan.

The then-Soviet Union and the United States suspended touchdowns after a string of successful moon landings in the 1960s and 1970s. China joined the elite club in 2013, India in 2023.But I also saw it last year Landing craft from Russia and Japanese private companies crash into the moon. In 2019, an Israeli nonprofit organization's lander crashed.

Next month, SpaceX will provide lifts for the lander from Intuitive Machines.

In addition to flight experiments for NASA, Astrobotic has launched its own cargo transportation business, shipping its 6-foot-tall (1.9-meter-tall) Hayabusa lander with rock chips from Everest and toy-sized objects it catapults from Mexico. I packed everything up to my car. It will reach and cruise the moon’s surface, collecting the ashes and DNA of deceased space enthusiasts, including “Star Trek” creator Gene Roddenberry and science fiction writer Arthur C. Clarke.

The Navajo Nation recently asked for the launch to be postponed because of the human remains. He said it would be a “grave desecration” of the celestial bodies worshiped by Native Americans. Thornton said the December challenge was too late, but promised to work to find a “good path forward” with the Navajo Nation for future missions.

Celestis, one of the spaceflight memorial companies that purchased space for the lander, said in a statement that no single culture or religion owns the moon and should not be able to veto the mission. There will be more debris in the rocket’s upper stage, and once released from the lander, it will orbit the sun indefinitely all the way to Mars.

Freight rates for Hayabusa range from a few hundred dollars to $1.2 million per kilogram (2.2 pounds), not enough for Astrobotic to break even. But Astrobotic CEO John Thornton says that’s not the point for this first flight.

“A lot of people’s dreams and hopes rest on this,” he said.

Source: www.nbcnews.com

Apple Vision Pro Expected to Launch between Late January and Early February

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We’ve known about the Vision Pro for more than six months now (not to mention it’s been rumored for years), but Apple’s first “spatial computing” device is expected to arrive in consumer electronics heading into the new year. One of the biggest question marks. The $3,499 headset was given an “early 2024” release date when it was announced at WWDC in June, but the company hasn’t provided further specifics since then.

Apple oracle Ming-Chi Kuo Provided an early holiday gift He narrowed down the system’s release date to “late January to early February.” According to the analyst, the first Vision Pro will be shipped to Apple within about a month, bringing the total number of units shipped this year to about 500,000 units.

Company’s accurate target There are still open-ended questions remaining for this year. About a month after the device was announced, it was reported that Apple had reduced its forecast from around 1 million units to “less than 400,000 units.”

Even the latest figure of 500,000 is small for a company of Apple’s enormous size and influence. Keep in mind that the company should ship more than 200 million iPhones this calendar year.

But Vision Pro is widely considered to be Tim Cook’s biggest challenge in his 12 years as CEO. Not only is this an entirely new category and form factor for the company, but it’s also an exorbitant price point, even for customers accustomed to paying extra for Apple products. Add to that the fact that VR has not lived up to expectations for decades, and we have a big uphill battle ahead.

Kuo calls Vision Pro “Apple’s most important product in 2024.” That’s a tough statement to argue with, given years of speculation and all the time and money the company has undoubtedly poured into the headset.

Source: techcrunch.com

Utilizing New Technology to Detect Cancer Early: The Impact on Calderdale and Huddersfield NHS Foundation Trust in West Yorkshire

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A West Yorkshire NHS Trust is utilizing advancements in technology, such as artificial intelligence and surgical robots, to achieve crucial cancer targets and alleviate widespread pressure on hospitals.

Calderdale and Huddersfield NHS The Foundation Trust is meeting three important cancer targets established by the government.

These targets include a waiting time of 28 days for patients who receive an emergency referral and are diagnosed with an infection or cancer, a 31-day wait from the patient’s treatment decision to the first treatment, and a 62-day wait from the emergency GP referral to the first treatment.

Sky News was given a tour of the innovations behind the hospital’s results, starting with a diagnostic test called Cytosponge. The Cytosponge is a small capsule with a string attached that is swallowed by the patient. When dissolved in the stomach, a brush collects cells from the esophageal lining, which are then analyzed for abnormalities.

image:
New diagnostic test site sponge could help doctors find cases of esophageal cancer faster

Cytosponges are used as an alternative to longer and more invasive endoscopies. Patients find the cytosponge less invasive and report a quicker procedure time.

…

Source: news.sky.com

Save 20% on a TechCrunch Early Stage 2024 pass when you buy by January 2nd

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Will 2024 be the year you do whatever it takes to take your startup ambitions to the next level? Hey, yeah! Building on that entrepreneurial spirit, we offer holiday gifts that wrap around New Year’s resolutions you’ll actually want to keep. 20% off the already low launch price of Founders Pass and Investor Pass Attending TechCrunch Early Stage 2024 on April 25th in Boston, Massachusetts. This benefit is good Until January 1st at 11:59pm PT. Unwrap your festive gift and purchase your pass today.

For those not familiar with TC Early Stage, it is an important destination for ambitious startups and newly established startup founders. Here you can find leading founders, investors, entrepreneurs, and startup experts from across the technology ecosystem.

Learn from them in small group presentations and roundtables that focus on the core topics every founder needs to master.

  • It is attracting media attention.
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Do you consider yourself a startup expert? Want to join our plethora of speakers? Submit your application to the call for content by January 10th for a roundtable slot on TechCrunch Early Stage. You may be able to obtain it.

20% off passes To TechCrunch Early Stage 2024. buy a pass January 1st 11:59pm PT And we are determined to make 2024 the best year for startups ever.

Is your company interested in sponsoring or exhibiting at TC Early Stage 2024? Please contact our sponsorship sales team. Please fill out this form.

Source: techcrunch.com

Early Detection of Parkinson’s Disease Possible 30 Years Before Onset of Symptoms, Scientists Find

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Researchers have discovered a way to detect Parkinson’s disease up to 30 years before symptoms appear using biomarkers and PET scans. This breakthrough includes tracking neurodegeneration more sensitively than current methods and shows that rapid eye movement sleep behavior disorder (RBD) is an important early indicator of Parkinson’s disease. is identified. This discovery could lead to earlier diagnosis and treatment, potentially up to 10 years earlier than currently.

Researchers at The Florey and Austin Health in Melbourne, Australia, have demonstrated the potential to identify early indicators of Parkinson’s disease 20 to 30 years before the onset of symptoms. This breakthrough paves the way for early screening programs and intervention, potentially allowing treatment before significant damage occurs.

Researchers at the Florey Institute and Austin Health have demonstrated the possibility of identifying early indicators of Parkinson’s disease 20 to 30 years before the onset of symptoms. This breakthrough paves the way for early screening efforts and preventive treatment, long before permanent damage occurs.

Florey Professor Kevin Burnham said that although Parkinson’s disease, a debilitating neurodegenerative disease, is often thought of as a disease of the elderly, it actually begins in midlife and can last for decades. He said it may not be detected.

“Parkinson’s disease is very difficult to diagnose until symptoms become apparent, by which time up to 85 percent of the neurons in the brain that control motor coordination have been destroyed. At that point, many treatments are likely to be ineffective,” Professor Burnham said. “Our long-term goal is to find ways to detect diseases earlier and treat people before they cause harm.”

Advanced diagnostic technology

In a recently published study, neurologylead researcher Professor Burnham and colleagues explore how a known biomarker called F-AV-133 can be used in positron emission tomography (PET) scans to diagnose Parkinson’s disease and accurately track neurodegeneration. I’m explaining how it can be done.

In the Melbourne study, Austin Health’s Frawley Professor Chris Rowe and his team studied 26 patients with Parkinson’s disease, 12 controls, and 11 patients with rapid eye movement sleep behavior disorder (RBD), a strong indicator of Parkinson’s disease. I checked the name. .

Each person underwent two PET scans two years apart. Key findings include:

  • Currently available assessments of Parkinson’s disease showed no significant changes in clinical symptoms in any of the participants.
  • In contrast, PET scans showed “significant neuronal loss” in three key areas of the brains of people with the disease, making F-AV-133 more effective than what is currently available. also suggests that it is a sensitive means of monitoring neurodegeneration.

Further mathematical modeling yields the following calculation:

  • Slow nerve cell loss over a total of approximately 33 years in Parkinson’s disease
  • This loss takes about 10.5 years before the disease is detected on a PET scan.
  • Even if a PET scan detects the disease, it will take another six and a half years for motor symptoms to appear.
  • It takes about 3 years after physical symptoms appear until a clinical diagnosis is confirmed.
  • This corresponds to approximately 22.5 years of neuronal loss before clinical symptoms are sufficient for diagnosis.

Professor Burnham said the findings pave the way for the development of screening protocols to diagnose and treat Parkinson’s disease up to 10 years earlier than is currently possible. It may also help identify patients for clinical trials.

What is RBD?

  • RBD stands for Rapid Eye Movement Behavior Disorder.
  • Patients with RBD scream, thrash, and sometimes move violently during sleep, enacting vivid and disturbing dreams.
  • RBD is caused by a lack of muscle relaxation (sleep paralysis).
  • 90% of RBD patients develop Parkinson’s disease.
  • Half of all Parkinson’s patients have RBD.
  • RBD is an important warning sign for early Parkinson’s disease.
  • If you have RBD, see a sleep specialist or neurologist.

Reference: “Use of 18F-AV-133 VMAT2 PET Imaging to Monitor Progressive Nigrostriatal Degeneration in Parkinson’s Disease”, Leah C. Beauchamp, Vincent Dore, Victor L. Villemagne, SanSan Xu, David Finkelstein, Kevin J. Barnham, Christopher Rowe, 28 November 2023 neurology.
DOI: 10.1212/WNL.0000000000207748

Source: scitechdaily.com

Astrobotic readies for early January launch of Peregrine lunar module

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astrobotic‘s first lunar module is ready for launch.

The company announced Tuesday that the lander, called Peregrine, has completed final inspection and refueling after mating with United Launch Alliance’s Vulcan Centaur rocket last month. All that remains is the January 8th launch — and then, of course, the historic moon landing.

“If you’ve followed the lunar industry, you know that landing on the moon is incredibly difficult,” Astrobotic CEO John Thornton said in a statement. . “That being said, our team has continually exceeded expectations and demonstrated incredible ingenuity during flight reviews, spacecraft testing, and major hardware integration.”

“We are ready for launch and landing.”

The Peregrine lander, which is approximately 2 meters tall, will carry 20 payloads for government and commercial customers. The lander has a payload of 90 kg and will operate for approximately 192 hours after landing on the moon. During that time, it provides power and communications to the payload. According to Astrobotic’s payload user guide on his website, the company charges about $1.2 million per kilogram of mass delivered to the lunar surface.

Astrobotic is performing this mission as part of a $79.5 million contract from NASA under NASA’s Commercial Lunar Payload Services (CLPS) program. The company also won her second CLPS contract for the larger Griffin lander. The mission is scheduled to launch at the end of 2024.

Pittsburgh-based Astrobotic is one of the few commercial companies betting on the growing market for lunar payload delivery services. Other companies include Intuitive Machines, which aims to launch its first lander on January 12, days after Peregrine, Firefly Aerospace, and the Japanese company whose moon launch attempt failed earlier this year. Includes ispace etc.

After Peregrine lifts off from Cape Canaveral, Florida, the spacecraft will perform a series of burns to position it for landing on the moon’s surface on February 23.

Astrobotic isn’t the only company with a lot at stake in the January 8 launch. This mission also marks the first flight of United Launch Alliance’s Vulcan Centaur rocket. The rocket was hit by delays that postponed its debut for years. . ULA aims to launch several Vulcan flights next year and will ultimately need to sign a multibillion-dollar 38-vehicle launch deal with Amazon for its Project Kuiper satellite broadband constellation.

Astrobotic and ULA originally targeted a Dec. 24 launch date, but it was later postponed to give ULA time to complete a wet dress rehearsal. According to ULA, the wet dress was finally completed on December 14th.

Source: techcrunch.com

AI trained on extensive life stories has the ability to forecast the likelihood of early mortality

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Data covering Denmark’s entire population was used to train an AI that predicts people’s life outcomes

Francis Joseph Dean/Dean Photography/Alamy Stock Photo

Artificial intelligence trained on personal data covering Denmark’s entire population can predict people’s likelihood of dying more accurately than existing models used in the insurance industry. Researchers behind the technology say it has the potential to have a positive impact on early prediction of social and health problems, but must be kept out of the hands of large corporations. There is.

Sune Lehmann Jorgensen The researchers used a rich Danish dataset covering the education, doctor and hospital visits, resulting diagnoses, income, and occupation of 6 million people from 2008 to 2020.

They converted this dataset into words that can be used to train large-scale language models, the same technology that powers AI apps like ChatGPT. These models work by looking at a set of words and statistically determining which word is most likely to come next based on a large number of examples. In a similar way, the researcher’s Life2vec model can look at the sequence of life events that form an individual’s history and determine what is most likely to happen next.

In the experiment, Life2vec was trained on all data except for the last four years of data, which was kept for testing. Researchers took data on a group of people aged 35 to 65, half of whom died between 2016 and 2020, and asked Life2vec to predict who lived and who died. This was 11% more accurate than existing AI models and life actuarial tables used in the financial industry to price life insurance policies.

The model was also able to predict personality test results for a portion of the population more accurately than AI models trained specifically to do the job.

Jorgensen believes the model has consumed enough data that it has a good chance of shedding light on a wide range of topics in health and society. This means it can be used to predict and detect health problems early, or by governments to reduce inequalities. But he stresses that it can also be used by companies in harmful ways.

“Obviously, our model should not be used by insurance companies, because the whole idea of ​​insurance is that if some unlucky person suffers some kind of incident, dies, loses their backpack, etc. ‘Because we share the lack of knowledge about what to do, we can share this burden to some extent,’ says Jorgensen.

But such technology already exists, he says. “Big tech companies that have large amounts of data about us are likely already using this information against us, and they are using it to make predictions about us. It is.”

Matthew Edwards Researchers from UK professional institutes the Institute of Actuaries and the Faculty of Actuaries say that while insurers are certainly interested in new forecasting techniques, the bulk of decision-making is based on a type of model called a generalized linear model. The research is done using AI, which he says is rudimentary compared to this research. .

“If you look at what insurance companies have been doing for years, decades, centuries, they’ve taken the data they have and tried to predict life expectancy from that,” Edwards said. “But we are deliberately conservative in adopting new methodologies, because when we are creating policies that are likely to be in place for the next 20 or 30 years, the last thing we want is to make any significant mistakes. . Everything can change, but slowly because no one wants to make mistakes.”

topic:

Source: www.newscientist.com

Neanderthals May Have Been Early Risers, New Study Finds

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When the ancestors of modern Eurasians migrated from Africa and interbred with the archaic humans of Eurasia, namely Neanderthals and Denisovans, the DNA of the archaic ancestors became anatomically integrated into the genomes of modern humans. homo sapiens. This process could accelerate adaptation to Eurasian environmental factors, such as reduced UV radiation and increased seasonal variation. In a new study, scientists from Vanderbilt University, the University of Pennsylvania, and the University of California, San Francisco have discovered lineage-specific genetic differences in circadian genes and their regulatory elements between humans and Neanderthals. They found that the introgressed genetic variants were enriched with effects on circadian regulation and consistently increased morningness tendencies in Europeans. The results expand our understanding of how the genomes of humans and our closest relatives responded to environments with different light-dark cycles.

Velasquez Alsuley other. They found that genetic material from Neanderthal ancestors may contribute to the tendency of some people today to be early risers, the type of people who wake up early and go to bed more easily. Image credit: Holger Neumann / Neanderthal Museum.

All anatomically modern humans trace their origins to the African continent about 300,000 years ago, where environmental factors shaped many of their biological characteristics.

They arrived in Eurasia 70,000 years ago, but other humans, Neanderthals and Denisovans, lived there for more than 400,000 years.

These archaic humans diverged from anatomically modern humans about 700,000 years ago, and as a result, humans and archaic hominid ancestors evolved under different environmental conditions.

“Although there was considerable variation in the latitudinal range of each group, Eurasian hominids primarily lived at consistently high latitudes and were therefore exposed to larger amplitude seasonal fluctuations in photoperiod,” said the University of California. said the San Francisco school. Dr. John Capra and his colleagues.

“Given the influence of environmental cues on circadian biology, we hypothesized that these separate evolutionary histories produced differences in circadian traits adapted to different environments.”

Although previous studies have shown that many of the archaic ancestors of modern humans are not beneficial and have been removed by natural selection, some archaic hominin variants that remain in human populations has shown evidence of adaptation.

For example, archaic genetic variation is thought to be associated with differences in hemoglobin levels, immune resistance to new pathogens, levels of skin pigmentation, and fat composition among Tibetans at high altitudes.

Changes in patterns and levels of light exposure have biological and behavioral effects that lead to evolutionary adaptations.

Scientists have extensively studied the evolution of circadian adaptations in insects, plants, and fish, but humans have been less well studied.

The Eurasian environment where Neanderthals and Denisovans lived for hundreds of thousands of years is located at higher latitudes and has more variable daylight hours than where modern humans evolved before leaving Africa.

Dr. Capra and his co-authors therefore investigated whether there was genetic evidence for differences in circadian clocks between Neanderthals and modern humans.

Using a combination of literature searches and expert knowledge, they defined a set of 246 circadian genes.

They found hundreds of genetic variations unique to each strain that can affect genes involved in the circadian clock.

Using artificial intelligence techniques, they identified 28 circadian genes that contain mutations that could alter splicing in archaic humans and that may be differentially regulated between modern and archaic humans. identified 16 circadian genes.

This indicates that there may be functional differences between the circadian clocks of ancient and modern humans.

Eurasian modern humans and Neanderthal ancestors interbred, so some humans may have acquired circadian variation from Neanderthals.

To test this, researchers investigated whether introgressed genetic variants were associated with the body’s preferences for wakefulness and sleep in a large cohort of hundreds of thousands of people at UK Biobank. did.

They found a number of introgressed mutants that affected sleep preferences, and most surprisingly, they found that these mutants consistently increased morningness, or the tendency to rise early.

This suggests a directional influence on this trait and is consistent with adaptations to high latitudes observed in other animals.

Increased morning time in humans is associated with a shortened circadian clock period. This may be beneficial at high latitudes, as it has been shown that sleep and wakefulness can be coordinated more quickly with external timing cues.

Shortening of the circadian period is required to synchronize the long summer light period at high latitudes in Drosophila, and selection for a shorter circadian period results in a latitudinal shift with increasing latitude in natural Drosophila populations. There is a latitudinal gradient in which the period decreases.

Therefore, the bias toward morningness in introgressed mutants may indicate selection for shortened circadian periods in populations living at high latitudes.

The tendency to be a morning person may have been evolutionarily beneficial to our ancestors who lived in the high latitudes of Europe, and would have been a Neanderthal genetic trait worth preserving.

“By combining ancient DNA, extensive genetic studies in modern humans, and artificial intelligence, we discovered substantial genetic differences in the circadian systems of Neanderthals and modern humans,” Dr. Capra said. .

“And by analyzing fragments of Neanderthal DNA that remain in the genomes of modern humans, we discovered surprising trends, many of which influence the regulation of circadian genes in modern humans. These effects are primarily in the consistent direction of increasing Neanderthal tendencies.” Morning people. ”

“This change is consistent with the effects of living at high latitudes on animals’ circadian clocks, and changes in seasonal light patterns may allow them to adjust their circadian clocks more quickly. ”

“Our next steps include applying these analyzes to more diverse modern human populations and investigating the effects of the Neanderthal variants we identified on circadian clocks in model systems. and applying similar analyzes to other potentially adaptive traits.”

of the team paper It was published in the magazine Genome biology and evolution.

_____

Kayla Velasquez-Arsley other. 2023. Archaic genetic introgression shaped human circadian characteristics. Genome biology and evolution 15 (12): evad203; doi: 10.1093/gbe/evad203

Source: www.sci.news

How did Paranthropus, a peculiar, ape-like early hominin, manage to survive for so long?

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P. Prairie/E. Daines/Science Photo Library

It’s not often that a respected professor embarks on an investigation into a scientific discovery by a 15-year-old, but in 1938 Robert Bloom made an exception. The British-born paleontologist was keenly aware that South Africa in the 1930s was gaining a reputation for extremely primitive-looking hominin fossils. So when he heard that elementary school student Gerd Terblanche had discovered a fragment of a human skull in a cave there, he immediately tracked him down. Bloom’s visit to the boy’s school was successful. The boy later recalled that he was walking around with children. “Probably the world’s four most precious teeth are in his pants pocket.”.

Within a few months, Bloom completed his analysis of the fossil. He determined that they were different from anything previously discovered; He gave ancient humans a new name. paranthropus.

However, although he was convinced that the remains were valuable, paranthropus He never became famous. Perhaps it was because it was a misfit. It resembled one of our small-brained ancestors, but existed on Earth long after other ape-like hominids were replaced by large-brained hominins. Even among paleoanthropologists, paranthropus They are depicted as a “forgotten” human race.

It probably won’t last very long. Spurred by the discovery of more fossils, researchers are finally starting to re-evaluate this addition to the evolutionary tree – and their research suggests it was one of the strangest. ing. paranthropus They may have been skilled tool makers, but they also may have grazed like cows and communicated with low calls like elephants. The question now is whether this research will bring us any closer to understanding how the last apemen survived in a world dominated by…

Source: www.newscientist.com

Bluesky, X’s competitor, reaches 2 million users; federation to launch in early next year

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Bluesky is a company building a decentralized alternative to Twitter/X. announced It now has 2 million users, an increase of another 1 million since September, despite still being an invite-only app. It also revealed deadlines for other important goals, saying it plans to have a public web interface up and running by the end of this month and start federation by early next year.

The latter is one of the most important differentiators between Bluesky and X, as it allows Bluesky to function as a more open social network. This means it works more like Mastodon, where users can choose which servers to join and move their accounts around freely. This is what Bluesky today claims is “billionaire-proof” and criticizes Elon Musk’s ownership of Twitter, now known as X.

“Rather than being bound to the whims and black-box algorithms of private companies, you have the freedom to choose (and exit) at any time.” Explained in company blog post. “And wherever you go, your friends and relationships will be there too,” it states.

Similar to Mastodon, a decentralized service, federation allows anyone to run their own service and connect to other services running the same protocol. For Bluesky, this is done like this: AT protocol The company is also developing consumer services and mobile apps in parallel. But his other major decentralized social network, Mastodon, uses an established protocol, his ActivityPub, which has grown significantly in the months since Musk’s acquisition of Twitter. It is attracting attention.

Since then, other companies have adopted ActivityPub and Mastodon, including Mozilla, Flipboard, Medium, and Automattic (WordPress.com’s parent company). Unless Bluesky makes the AT protocol and ActivityPub interoperable in some way, there could be challenges regarding Bluesky’s ultimate reach. Bridging Maybe the two of you Technically It’s possible, but it’s more likely to be in the future, not in the near future.

Meanwhile, Bluesky is working to make its services more accessible, including launching a public web interface later this month. This will allow anyone to view his Bluesky posts, even if they don’t have an account. This could make the network more promising in terms of being a true competitor to X in breaking news and conversation, but it could expose Bluesky users’ posts to the outside world in ways they are not ready for. There is also. (This app currently does not have an option to set your profile to “private” like Twitter/X does. some users is not Happy about this. )

Despite its growth, Bluesky’s reluctance to drop its invite-only status and open its network to more users has allowed other competitors of X to gain a foothold. Last month, for example, Meta CEO Mark Zuckerberg announced that Instagram Threads, an alternative to X, had just under 100 million monthly active users. He believes he can reach 1 billion users in the next few years. Threads also plans to interoperate with ActivityPub in the future.

Bluesky’s announcement follows Threads’ rapid release of features to make the app more competitive with X, including a chronological feed, support for displaying likes, search, and (free) Includes an edit button, web version, voting, GIF support, and more. , topic tags, and soon a developer API. Mastodon also took advantage of the opportunity presented by the Twitter acquisition and launched an easier-to-use version of its service in September of this year. However, Mastodon currently has 1.6 million monthly active usersHowever, it is much smaller than a thread.

In addition to today’s news, Mr. Bluesky also provides mobile push notifications, shareable user lists, email verification, advanced feed and thread settings for sorting and filtering posts, a media tab in user profiles, and a user profile for your own users. We also mentioned other recently released features, such as a Likes tab for profiles. , the suggestions below, and various accessibility improvements.

Bluesky started life as a Twitter project under Jack Dorsey, but the company was spun off from Twitter. $13 million How to start research and development. Mr. Dorsey sits on its board of directors. This year, the company raised an $8 million seed round led by Neo to further its development and transformed from a public benefit LLC to a public benefit C Corp.

Source: techcrunch.com