Adopting a low FODMAP diet may be more effective than medication in reducing symptoms of irritable bowel syndrome

Eating less of some types of foods and more of others may ease irritable bowel syndrome

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Two types of diets are more effective at treating irritable bowel syndrome (IBS) than drugs, a trial has found.

One diet was designed to be low in FODMAPs, a group of carbohydrates similar to sugars found in dairy products, wheat, and certain fruits and vegetables. The second, less common approach used for IBS is an adaptation of a low-carbohydrate diet that is high in fiber and low in other types of carbohydrates, such as sugar and starch.

In a randomized trial, both diets showed better symptom improvement than standard drug treatment after four weeks.

IBS can cause mysterious symptoms such as diarrhea, constipation, bloating, and abdominal pain that increase or decrease over time. The underlying cause of this condition is unknown.

The usual advice is to avoid common triggers such as caffeine, alcohol and spicy foods. Symptomatic treatments such as laxatives for constipation and drug therapy for diarrhea may be given.

If these measures don’t work, you may want to consider cutting back on foods high in FODMAPs. FODMAPs tend not to be digested until they reach the colon, which is why they are thought to cause bloating and diarrhea. This encourages the colon to retain water, and when the molecules are consumed by bacteria, gas is produced and causes bloating.

Sanna Niebacka Researchers from the University of Gothenburg in Sweden wanted to find out how a regular low-FODMAP diet compared to an alternative approach: high in fiber but low in carbohydrates. In practice, this means eating high-fat, high-protein foods such as meat and dairy products, and sources of fiber include nuts, seeds, beans, and vegetables such as cabbage.

The research team asked around 300 people with IBS to use one of three approaches depending on their symptoms: take medication or adopt one of two diets. The diet provided people with free grocery delivery, as well as detailed meal plans and recipes.

After one month, 76% of the low-FODMAP group reported a significant reduction in symptoms, compared with 71% of the low-carbohydrate diet group and 58% of the drug treatment group.

The big surprise was that a low-carbohydrate, high-fiber diet that didn’t exclude FODMAP-containing foods was about as effective as a low-FODMAP approach, Nybacka says. “We can’t answer any questions as to why. It appears that altering carbohydrate content and reducing FODMAP intake may be beneficial.”

but hazel everitt Researchers at the University of Southampton in the UK say the trial would have been more informative if it had lasted longer. “The problem with many of the IBS diets that have been proposed is that they are very difficult to stick to long-term,” she says.

Participants were followed for up to six months, but during the last five months participants who were initially offered drug treatment were also given dietary advice.

Niebacka says one potential problem with the low-carbohydrate, high-fiber diet is that this group of people had slightly elevated blood cholesterol levels. Therefore, you should seek your doctor’s advice before adopting this diet, she says.

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Source: www.newscientist.com

Why recycling may not always be the most effective solution for combating climate change

Recycling is not a silver bullet to stop climate destruction. Far from it. Potential Impact – Savings of approximately 11 gigatons of carbon dioxide (CO2) over 30 years. Even if the world recycled more than 80 percent of its municipal waste, that amount would be overshadowed by the greenhouse gases emitted by fossil fuels and industry – a staggering 36.8 gigatons in 2022 alone.

In the UK, it is estimated that recycling 18 million tons of CO2 annually. This is equivalent to removing five million cars from the road. While promising, it is only a very small fraction of the emissions generated by fossil fuels and industry each year, which are about 200 times greater than those from agriculture and the global fashion industry.

These numbers may be discouraging, but what can an individual do to help?

Reduce, Reuse, Recycle

First and foremost, do not give up on recycling. It is a simple way to reduce landfill waste and slow down the depletion of the earth’s resources.

To put into perspective the impact of recycling, dividing the 18 million tonnes by the UK’s population of 67 million, the average Briton is saving about 269kg of CO2 per year through recycling.

According to DEFRA, Britons recycled 44% of household waste in 2021. By recycling 100% of household waste, an individual could save up to 610kg per year.


If you truly want to make a difference, focus on making sustainable choices early on in the consumption process. Opt for loose fruits and vegetables, solid detergents, repair and reuse old clothes, and most importantly, buy less.

Emphasize the Reduce and Reuse aspects of the 3R mantra and resort to recycling only when other options are exhausted.

Let’s Start With One Thing

If you feel overwhelmed, start by making one sustainable change at a time. For example, by using a reusable water bottle instead of plastic ones, you can save 20kg of CO2 per year.

A review of thousands of studies worldwide suggests that changes like taking fewer long-haul flights, using public transport, and improving home energy efficiency are significant in reducing household carbon footprints.

While recycling alone may not be the solution to climate change, it is a step in the right direction. Each individual has the power to make a positive impact.

This article addresses the question posed by Jensen Pitts via email: “Can recycling really make a difference?”

If you have any questions, please email us at: questions@sciencefocus.com or reach out to us via Facebook, Twitter, or Instagram (don’t forget to include your name and location).

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Source: www.sciencefocus.com

Study: Certain plants are more effective than others in removing air pollution through green walls

Biologists are University of Surrey They investigated interspecific variation in particulate matter accumulation, washout, and retention in 10 broad-leaved plants, focusing on leaf characteristics.

thomson other. We found that the interaction between macromorphology and micromorphology in green-walled plant species determines their particulate matter removal ability.Image credit: Thomson other. 2024., doi: 10.1016/j.scitotenv.2024.170950.

Green wall is a vertical system that has received particular attention because it can be installed without occupying additional space at street level.

They also offer other benefits, such as reduced dependence on existing soil conditions and additional ecosystem services.

Green wall is a term that includes walls covered with all forms of vegetation.

Green facades and living walls are two types of green walls, where green facades usually include climbing plants, whereas living walls include planting materials and plants to support a more diverse variety of plants. Includes technology.

The reduction of air pollutants by green walls depends on several factors such as plant type, barrier dimensions, leaf area index, humidity, wind speed, and orientation of the location.

“By planting vertically against green walls, communities can purify the air without taking up too much street space,” said Mamatha Thomson, a postgraduate researcher at the University of Surrey.

“Our study suggests that this process depends not only on leaf shape but also on the micromorphological properties of the leaf surface.”

“We believe that the right mix of species creates the most effective green walls. We look forward to conducting further research to see if we are right. .”

In this study, Thomson et al. planted 10 species: Evergreen Candy Tuft (Iberis sempervirens), Ivy (hedera helix) And that Wild marjoram (Ornamental pill beetle)in a custom-built 1.4 meter green wall.

The leaves of the evergreens candytuft and ivy were found to be particularly good at trapping pollutant particles, both large and small.

Meanwhile, rain was able to wash most of the pollutants from the lavender's hairy leaves.

Candytuft and marjoram also performed well in washing away small pollution particles.

“We hope that urban planners and infrastructure experts can use our findings to think more carefully about what they plant,” said Prashant Kumar, a professor at the University of Surrey.

“Having a green wall is a great way to remove pollution, but what you plant on top of it can make a big difference to its success.”

of result It was published in the magazine Total environmental science.

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Mamatha Thomson other. 2024. Investigating the interplay between particulate matter scavenging, scavenging, and leaf properties in green-walled species. Total environmental science 921: 170950; doi: 10.1016/j.scitotenv.2024.170950

Source: www.sci.news

Is spam email effective for receiving responses?

DDo spam emails actually work? We're not talking about suspicious phishing emails, we're talking about annoying ads and sales pitches. Perhaps the answer is yes, otherwise spammers wouldn't care, but I find it hard to believe.
Ali Farhan, Manchester

Please send new questions to
nq@theguardian.com
.

Reader replies

wait a minute. I'm going to email 300 million people and ask them. el comentario

It's more effective than doing nothing. This is the secret behind all marketing. one, another name

There are many different types of spam. More targeted types (e.g., an email from a company you've previously shopped with telling you they have a sale) can tell people what they might be interested in and potentially lead to a sale. That's why it works so well. Anything that's completely fake or untargeted won't be very effective.

But the reason companies use this kind of email is because it's so cheap. Send thousands of emails for just a few pounds. It only takes a few people to respond to make it worthwhile. For many of them, if 1 out of 1,000 people who receive an email buys something, they can make a profit from it. Meanwhile, everyone's inboxes suffer.
Snowy John

I work in sales and send out so-called spam emails. (This is in the business-to-business sales space.) There's a trick behind this. I don't reach out unless I have a reason and think there's something I can do to help. This is done by looking at the role the company is in, the types of technology, and evaluating its growth. Emails are personalized. Mixed in with my phone calls, I also embed videos of me reviewing websites in my emails.

It definitely works. Will everyone react? Absolutely not. Some people show interest, but it takes time to strike up a conversation. But that's part of sending an email. To get people in and out. If you choose not to contact us anymore, please do not contact us again.
Konobu 2020

I really don't understand people who don't care about spam or sell things on the street. I ignore everyone and look it up myself if I need to buy something. I may be missing out on countless deals, but I'll take a chance. Babylonian SheDevil03

My inbox is mostly unusable due to emails from companies I love and have previously purchased from. I receive at least two emails a month from companies that sell belts. How many quality belts can I buy? I might buy another one in five years, but I won't buy it from that annoying spammer. mega road

Last week's N&Q was about beans, this week it's about Spam. Will it be mushrooms next Sunday? Fried onion rings? Please wait and see… eddie miscellaneous post

I especially despise people who have an “unsubscribe” button that doesn't actually work. They immediately rank at the top of my banned list. Oz Josh

Avoiding spam is a great way to waste time. bricklayer options

Source: www.theguardian.com

New Study Identifies the Most Effective Diet for Reducing Loud Snoring

Dealing with snoring can be a bothersome experience for everyone involved, whether it’s falling asleep on a public bus or waking a loved one. Researchers may have found the best diet to combat this issue.

Obstructive sleep apnea (OSA) is a common condition that puts people at risk for high blood pressure, stroke, heart disease, and type 2 diabetes. This is because OSA causes multiple disruptions during sleep due to loud snoring and interruptions in breathing.

The solution may lie in a diet rich in vegetables, fruits, and whole grains, as suggested by a new study published in the journal ERJ Open Research. This diet may help prevent or treat OSA.

In order to test this theory, researchers at Flinders University in Adelaide, Australia, used data from 14,210 participants in the US National Health and Nutrition Examination Survey. Participants were asked to list everything they had consumed in the past 24 hours, and the research team categorized their responses into three dietary patterns: a healthy plant-based diet, an unhealthy plant-based diet, and a diet high in animal products.

The “unhealthy” plant-based diet included high amounts of refined carbohydrates, potatoes, sugary drinks, sweets, desserts, and salty foods.

Additionally, participants completed a sleep questionnaire to determine the likelihood of having OSA. The researchers found that people with diets high in plant foods were 19% less likely to suffer from snoring caused by OSA. On the other hand, those who consumed an unhealthy plant-based diet were 22% more likely to have OSA.

Researchers believe that a healthy plant-based diet may be important due to its anti-inflammatory components and antioxidants, which can impact fat mass, inflammation, and muscle tone, thereby affecting a person’s OSA risk.

Dr. Johannes Melak, the chief researcher, emphasized that diet quality is important in managing the risk of OSA, and that a healthy plant-based diet may reduce inflammation and obesity.

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Source: www.sciencefocus.com

Probiotics found effective in reducing fatigue and memory loss related to prolonged COVID-19 infection

Probiotics, illustration of live microorganisms that can affect intestinal bacteria

ART-ur/Shutterstock

A daily cocktail of prebiotics and probiotics can help reduce fatigue, memory, and symptoms in people with long-term COVID-19 (symptoms that persist for months or years after being infected with COVID-19). May be useful in treating gastrointestinal complaints.

Although little is understood about long-term coronavirus infections, previous research has shown that people with the disease have lower levels of certain gut microbes than those without. Masu. In particular, they lack gut bacteria that produce compounds called short-chain fatty acids that regulate immune responses.

Siu Ng and his colleagues at the Chinese University of Hong Kong have formulated a mixture that boosts the production of short-chain fatty acids. The product, called SIM01, contained three probiotics (live bacterial strains) and three prebiotics (compounds that help the growth of beneficial gut bacteria).

They distributed this cocktail to 232 adults. Another group of 231 adults took a mixture containing starch and low-dose vitamin C. Both mixtures were taken twice a day for 6 months. All participants were residents of Hong Kong, had previously tested positive for COVID-19, and met the U.S. Centers for Disease Control and Prevention’s criteria for long-term COVID-19 infection.

Researchers used a questionnaire to assess 14 long-term COVID-19 symptoms in participants before treatment began and after treatment ended. At the end of the trial, people who received SIM01 were likely to experience relief from five long-term coronavirus symptoms: fatigue, memory loss, difficulty concentrating, general unwellness, and gastrointestinal upset. It was found to be about 2 to 2.5 times higher on average. The research team also found no serious side effects from the treatment.

Analysis of fecal samples taken before and after the trial revealed that SIM01 increases gut microbial diversity and promotes the growth of beneficial gut bacteria, Ng said. Therefore, she says, it could be useful in treating other conditions that are associated with disruption of the gut microbiome, such as chronic fatigue syndrome.

However, it is unclear how these changes in the gut reduce the symptoms of long-term coronavirus infection. timothy sampson At Emory University in Georgia. “It makes sense that the microbiome has the ability to mediate immune responses, but… [immune system] What is actually at the root of [long covid] You get symptoms,” he says.

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Source: www.newscientist.com

Artificial Intelligence identifies novel antibiotics effective against drug-resistant bacteria

Methicillin-resistant Staphylococcus aureus (MRSA)

Shutterstock / Katerina Conn

Artificial intelligence has contributed to the discovery of new classes of antibiotics that can treat infections caused by drug-resistant bacteria. This could help fight antibiotic resistance, which claimed more than 1.2 million lives in 2019, and that number is expected to increase in the coming decades.

A new antibiotic compound has proven to be a promising treatment for both methicillin resistance and tolerance in tests in mice. Staphylococcus aureus (MRSA) and vancomycin resistance Enterococcus – Bacteria that have developed resistance to drugs commonly used to treat MRSA infections.

“our [AI] The model not only tells us which compounds have selective antibiotic activity, but also why in terms of their chemical structure. ” Felix Wong at the Broad Institute of MIT and Harvard University in Massachusetts.

Wong and colleagues aimed to show that AI-driven drug discovery can go beyond identifying specific targets to which drug molecules can bind to predicting the biological effects of entire classes of drug-like compounds.

First, we tested the effects of over 39,000 compounds. Staphylococcus aureus Three types of human cells: liver, skeletal muscle, and lung. The result was training data for the AI ​​model to learn the chemical atoms and bond patterns of each compound. This has enabled AI to predict both the antibacterial activity and potential toxicity of such compounds to human cells.

The trained AI model then analyzed 12 million compounds through computer simulations and found 3,646 compounds with ideal drug-like properties. Additional calculations identified chemical substructures that could explain the properties of each compound.

By comparing such substructures of different compounds, researchers identified a new class of potential antibiotics and ultimately two non-antibiotics that can kill both MRSA and vancomycin-resistant bacteria. discovered a toxic compound Enterococcus.

Finally, researchers used mouse experiments to demonstrate the effectiveness of these compounds in treating skin and thigh infections caused by MRSA.

Only a few new classes of antibiotics, such as oxazolidinones and lipopeptides, have been discovered to be effective against both MRSA and vancomycin-resistant bacteria. Enterococcus – and says resistance to such compounds is increasing. james collins at the Broad Institute, where he co-authored the study.

“Our research has identified one of the few new classes of antibiotics in 60 years that complements other antibiotics,” he says.

Researchers are working to design entirely new antibiotics and discover other new drug classes, such as compounds that selectively kill aging and damaged cells involved in conditions such as osteoarthritis and cancer. are starting to use this AI-driven approach.

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Source: www.newscientist.com