How Exercise Can Be as Effective as Antidepressants in Reducing Depression

jogging in fog or mist

Exercise: An Effective Treatment for Depression

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Experiencing a post-workout mood boost is common, and a recent review highlights just how impactful this effect can be. Simple activities like walking or gardening can alleviate depression symptoms as effectively as psychotherapy or antidepressants.

“This research reinforces that exercise is a viable option for individuals suffering from depression, showing that it can rival the effectiveness of psychotherapy or medication,” states Andrew Clegg from the University of Lancashire, UK.

A prior Cochrane Library review in 2013 discovered that exercise alleviates depression symptoms comparably to standard treatments like antidepressants and cognitive behavioral therapy (CBT), which focuses on modifying thought patterns and behavior.

Consequently, health authorities advocate regular exercise for depression management. The UK’s National Institute for Healthcare Excellence (NICE) suggests engaging in aerobic activities such as jogging for ten weeks, typically in conjunction with other therapies for optimal results.

Since the 2013 review, numerous clinical trials have surfaced, prompting the Cochrane Library to embark on an updated review. “This new review nearly doubles the existing evidence base from the previous publication,” comments Clegg, a co-author of the review.

Clegg and colleagues reviewed data from 69 randomized controlled trials involving nearly 5,000 adults diagnosed with mild to severe depression or showing elevated depression symptom scores. Their analysis focused on 57 trials where participants were assigned to either an exercise group or a control group receiving no treatment.

Trial methodologies varied significantly, but usually directed participants to maintain a routine of low to moderate exercise—like gardening or brisk walking—compared to more vigorous activities like sprinting or soccer. Yoga and stretching were excluded, as these often incorporate meditative or breathing practices, which detracted from the study’s emphasis on pure physical activity.

The research indicated that exercise modestly reduced depression severity, characterized by feelings of sadness and disinterest in social activities.

“Clinically meaningful improvements were observed—individuals reported noticeable changes,” remarks Brendon Stubbs from King’s College London, who was not part of the review.

Furthermore, the team analyzed ten of the 59 trials that compared exercise to CBT and five trials involving participants on antidepressants devoid of an exercise component. Results indicated that, on average, regular exercise proved equally effective as these treatment modalities. “There was no significant difference in outcomes among the three,” emphasizes Emily Hird from University College London, who also did not partake in the study.

The research highlighted that light to moderate exercise outperformed intense workouts. This may be linked to higher adherence rates; as Stubbs explains, “Strenuous exercises often lead to dropout, thus diminishing the observed benefits.”

While the precise advantages of exercise remain under investigation, Stubbs suggests multiple potential mechanisms. Group activities could enhance social well-being, and acquiring new skills might boost self-esteem, fostering positive life changes.

Studies indicate that muscle-released chemicals, known as myokines, help reduce inflammation, which may exacerbate depression. One particular myokine, brain-derived neurotrophic factor, is known for promoting new brain cell growth, potentially aiding in the reconfiguration of negative thought patterns, as asserted by Stubbs. Interestingly, Clegg’s team discovered that resistance training, which generates more myokines, was more effective than aerobic workouts alone.

Collectively, these findings advocate for exercise as a depression treatment modality. However, since participants were aware of their group assignments, some gains might stem from placebo effects, where expectations influence symptom relief. Additionally, the majority of studies had limited participant numbers, which may impact reliability, according to Hurd.

Hurd advocates for larger studies to investigate optimal exercise types tailored for individuals and their unique challenges. “Currently, we lack clarity on who benefits most from different exercise forms,” she asserts. Individuals with severe depression might struggle to maintain exercise routines and may find more relief through CBT or antidepressants, both of which exhibit effectiveness akin to exercise in managing depression. Furthermore, some individuals may respond preferentially to specific activities based on their depression’s root causes.

Nevertheless, evidence consistently reveals the benefits of exercise for both mental and physical health. “Activities such as running, gym workouts, Pilates, and yoga all impart various positive effects. The most crucial aspect is to engage individuals in activities they enjoy,” concludes Stubbs.

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Source: www.newscientist.com

Quantum Computers with Recyclable Qubits: A Solution for Reducing Errors

Internal optics of Atom Computing’s AC1000 system

Atom Computing

Quantum computers, utilizing qubits formed from extremely cold atoms, are rapidly increasing in size and may soon surpass classical computers in computational power. However, the frequency of errors poses a significant challenge to their practicality. Researchers have now found a way to replenish and recycle these qubits, enhancing computation reliability.

All existing quantum systems are susceptible to errors and are currently unable to perform calculations that would give them an edge over traditional computers. Nonetheless, researchers are making notable advancements in the creation of error correction methods to address this issue.

One approach involves dividing the components of quantum computers, known as qubits, into two primary categories: operational qubits that manipulate data and auxiliary qubits that monitor errors.

Developing large quantities of high-quality qubits for either function remains a significant technical hurdle. Matt Norcia and his team at Atom Computing have discovered a method to lessen the qubit requirement by recycling or substituting auxiliary qubits. They demonstrated that an error-tracking qubit can be effectively reused for up to 41 consecutive runs.

“The calculation’s duration is likely to necessitate numerous rounds of measurement. Ideally, we want to reuse qubits across these rounds, minimizing the need for a continuous influx of new qubits,” Norcia explains.

The team utilized qubits derived from electrically neutral ytterbium atoms that were chilled close to absolute zero using lasers and electromagnetic pulses. By employing “optical tweezers,” they can manipulate each atom’s quantum state, which encodes information. This method allowed them to categorize the quantum computer into three distinct zones.

In the first zone, 128 optical tweezers directed the qubits to conduct calculations. The second zone comprised 80 tweezers that held qubits for error tracking, or that could be swapped in for faulty qubits. The third zone functioned as a storage area, keeping an additional 75 qubits that had recently been deemed useful. These last two areas enabled researchers to reset or exchange the auxiliary qubit as needed.

Norcia noted that it was challenging to establish this setup due to stray laser light interfering with nearby qubits. Consequently, researchers had to develop a highly precise laser control and a method to adjust the state of data qubits, ensuring they remained “hidden” from specific harmful light types.

“The reuse of Ancilla is crucial for advancing quantum computing,” says Yuval Borger from QuEra, a U.S. quantum computing firm. Without this ability, even basic calculations would necessitate millions, or even billions, of qubits, making it impractical for current or forthcoming quantum hardware, he adds.

This challenge is recognized widely across the atom-based qubit research community. “Everyone acknowledges that neutral atoms understand the necessity to reset and reload during calculations,” Norcia asserts.

For instance, Borger highlights that a team from Harvard and MIT employed similar techniques to maintain the operation of their quantum computer using 3000 ultra-cold rubidium atoms for several hours. Other quantum setups, like Quantinuum’s recently launched Helios machine, which uses ions controlled by light as qubits, also feature qubit reusability.

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Source: www.newscientist.com

Grayscale and Prune Algorithm: “Digital Nutritionist” Provides Tips for Reducing Screen Time

A professor, now regarded as a “digital nutritionist,” suggests that disabling the color on your phone and dedicating 30 minutes a week to pruning your online feeds can enhance consumers’ control over their digital media consumption.

These strategies, termed grayscale and algorithmic tolerance, are part of Dr. Kaitlyn Regehr’s many recommendations. She is an associate professor at the University of London and a prominent authority on digital literacy.

While much of the conversation centers on social media’s negative effects on children, Regehr’s focus is on combating digital illiteracy among parents, empowering them to better understand and use their children’s devices safely and effectively.

In her upcoming book, Smartphone Nation, Regehr advises taking an initial step by performing a digital “walkthrough” of your preferred app alongside friends and family.

“Switching your phone to GreyScale is one of the easiest and quickest methods to grasp how colors and images impact your user experience,” she notes. “This experience allows you to feel the addictive nature of these devices through their visual elements.”

Users can find instructions for this feature in Google Help for Android devices or Apple Support for iPhones.

On the flip side, algorithm resistance focuses on taking charge of the algorithm rather than allowing it to dictate your preferences. Thus, Regehr advocates for being deliberate about what you wish to see in your feed, and filtering out unwanted content for 30 minutes each week.

“When I had concerns about my family’s digital consumption… I struggled to find adequate guidance,” Regehr shares in her book. “I developed a framework to help myself and my family navigate the digital landscape. I came to see myself as a digital nutritionist.”

In a conversation with the Guardian, she expressed her support for school smartphone bans and initiatives promoting a smartphone-free childhood, but highlighted the necessity for more education to encourage families to think critically about their digital choices.

“Even if parents postpone giving their children smartphones until they are 15, they will still turn 16. It’s essential to equip them with the tools to navigate this environment effectively,” she emphasized. “Education on how these devices operate is crucial.”

Her forthcoming book, “Why Are We All Obsessed with the Screen and What You Can Do About It,” aims to bridge this knowledge gap, with new educational resources set to be introduced in schools later this month.

As per the UK’s first national survey, nearly all schools in the country have implemented a ban on mobile phone usage during school hours.

Driven by worries regarding children’s mental health, attention span, and online safety, a survey of over 15,000 schools revealed that 99.8% of primary schools and 90% of secondary schools enforce some form of ban.

“I advocate for my efforts towards a smartphone-free childhood,” stated Regehr, who directs the digital humanities program at UCL and previously explored the rapid amplification of extreme misogynistic content through social media algorithms. “My concern is that enforcing the ban can lead schools and lawmakers to feel complacent, believing they’ve fulfilled their responsibilities.”

Dedicated to two young girls, Regehr’s book aims to prompt a cultural shift. “I aspire to reflect on our generation as being less healthy and more skillfully ensnared, akin to looking back on previous norms like smoking in delivery rooms and not using seatbelts.”

“My aim is to foster cultural change to ensure their lives are better. This represents the largest threat to their health and well-being, and that is the challenge I wish to tackle. I believe change is possible; people simply need access to information.”

Smartphone Nation: Why We’re All Obsessed with Screens and What You Can Do by Dr. Kaitlyn Regehr is set to be published by Bluebird on May 15th.

Source: www.theguardian.com

Reducing high blood pressure may decrease the likelihood of developing dementia

Low blood pressure is associated with a lower risk of dementia

Shutterstock/Greeny

According to a large study from Chinese people, lowering hypertension reduces the risk of dementia and cognitive impairment.

Many studies link Hypertension is also known as hypertension, and is at a high risk of developing dementia.. Some studies have also shown that side effects of blood pressure treatment may be at a lower risk of dementia.

now, jiang he At the University of Texas Southwestern Medical Center, Dallas and his colleagues are directly considering the effectiveness of drugs that lower blood pressure for dementia and cognitive impairment.

They studied 33,995 people in rural China. They were all over 40 years old and had high blood pressure. Participants were split into one of two random groups, each with an average age of approximately 63 years.

On average, the first group actively received three antitherapeutic drugs, such as ACE inhibitors, diuretics, or calcium channel blockers, actively ensuring lower blood pressure. They also coached home blood pressure monitoring and lifestyle changes that help to reduce blood pressure, such as weight loss and alcohol and salt intake.

Another set treated as a control group achieved local treatment levels with the same coaching and more general levels of treatment, including on average one drug.

At follow-up appointments 48 months later, participants were tested for blood pressure and measured for signs of cognitive impairment using a standard questionnaire.

Concerns about hypertension begin when a person’s systolic pressure exceeds 130 mm mercury (mmHg) or when diastolic pressure exceeds 80 mmHg. blood pressure It has exceeded 130/80.

On average, many people who received the medication lowered their blood pressure from 157.0/87.9 to 127.6/72.6 mmHg, while the control group was able to take it from 155.4/87.2 to just 147.7/81.0 mmHg.

The researchers also found that 15% fewer people who received multiple drug therapies during the study received dementia diagnosis compared to the control group, and 16% suffered from cognitive impairment.

“The results of this study demonstrated that lowering blood pressure is effective in reducing the risk of dementia in patients with uncontrolled hypertensive conditions,” he says. “This proven and effective intervention should be widely adopted and expanded to alleviate the global burden of dementia.”

“Over the years, many people know that blood pressure is likely a risk factor for dementia. Zachary Malcolm At Washington University in Seattle.

Raj Shah Rush University in Chicago says it’s helpful to add evidence that treating high blood pressure can help stop dementia, but that’s just one of the dementia puzzles, as we affect brain abilities as we age.

“You need to treat hypertension for multiple reasons,” says Shah. “Because of people’s longevity and happiness, they can age healthyly over time.”

Marcum also says people should think more broadly than just blood pressure to avoid dementia. He says there is Other known risk factors This is associated with an increased risk of dementia, including smoking, inactivity, obesity, social isolation, and hearing loss.

And many factors are more influential at different stages of life. To reduce the risk of dementia, “a holistic approach is needed throughout your life,” says Shah.

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Source: www.newscientist.com

Reducing the Risk of Heart Disease: A New Approach


Quantum Universe

Quantum physics is confused. Luckily, scientists have been exploring it for years, and finally we are beginning to understand it all. Quantum Mechanics guide now easier. A Whistlestop tour to understand the basic theory that governs very small things.

Near-death experience

They left their bodies, witnessed a bright light, and returned forever. But will the survivors of near-death experiences (NDEs) get a glimpse of something great beyond that? Here’s what NDES can tell us about the mystery of our final moments:

Losing the world under the sea

Discover the lost landscape off the coast of Australia, engulfed in the ocean that could have lived over half a million years ago.

Mystical signals from deep space

Fast Radio Burst: Are these mystical signals from deep spaces becoming even more strangers?

plus

  • There’s a bit of hope: Having hope is a way to do better for your mental health than mindfulness.
  • New pieces of obesity puzzle: A better understanding of the human hypothalamus pathways has great medical potential and could lead to new treatments of obesity.
  • Q&A: Your question answered! This month: Does your name affect your physical appearance? Does something poop gold? How old is Jupiter’s Great Red Spot? Why is it so difficult to switch tasks? What’s the craziest thing ever stolen? And more!

Issue 417 for sale on Tuesday, March 18th, 2025

Don’t forget that BBC Science Focus It is also available on all major digital platforms. There is a version Android, Kindle Fire and Kindle e-book readersas well as iOS App For iPad and iPhone.

Source: www.sciencefocus.com

Reducing Bias, Improving Recruitment: How AI is Revolutionizing Hiring for Small Businesses

Artificial intelligence is trained on human-created content, known as actual intelligence. To train AI to write fiction, novels are used, while job descriptions are used to train AI for writing job specifications. However, a problem arises from this approach. Despite efforts to eliminate biases, humans inherently possess biases, and AI trained on human-created content may adopt these biases. Overcoming bias is a significant challenge for AI.

“Bias is prevalent in hiring and stems from the existing biases in most human-run recruitment processes,” explains Kevin Fitzgerald, managing director of UK-based employment management platform Employment Hero. The platform utilizes AI to streamline recruitment processes and minimize bias. “The biases present in the recruitment team are embedded in the process itself.”

One way AI addresses bias is through tools like SmartMatch offered by Employment Hero. By focusing on candidates’ skills and abilities while omitting demographic information such as gender and age, biases can be reduced. This contrasts with traditional methods like LinkedIn and CVs, which may unintentionally reveal personal details.

AI helps businesses tackle bias when screening for CVs. Photo: Fiordaliso/Getty Images

Another concern is how AI processes information compared to humans. While humans can understand nuances and subtleties, AI may lack this capability and rely on keyword matching. To address this, tools like SmartMatch evaluate a candidate’s entire profile to provide a holistic view and avoid missed opportunities due to lack of nuance.

SmartMatch not only assists in matching candidates with suitable roles but also helps small businesses understand their specific hiring needs. By analyzing previous hires and predicting future staffing requirements, SmartMatch offers a comprehensive approach to recruitment.

Understanding SME needs and employment history allows SmartMatch to introduce you to suitable candidates. Photo: Westend61/Getty Images

By offering candidates the ability to maintain an employment passport, Employment Hero empowers both job seekers and employers. This comprehensive approach to recruitment ensures that both parties benefit from accurate and efficient matches.

For small and medium-sized businesses, the impact of poor hiring decisions can be significant. By utilizing advanced tools like SmartMatch, these businesses can access sophisticated recruitment solutions previously available only to larger companies.

Discover how Employment Hero can revolutionize your recruitment process.

Source: www.theguardian.com

Strong evidence of Ozempic and Wegoby reducing alcohol consumption

People report lower alcohol cravings when using semaglutide

ShutterStock/David MG

According to the first randomized clinical trials of drugs for this purpose, semaglutide appears to help people who are truly obsessed with alcohol reduce their intake.

Semaglutide, sold under brand names including Wegovy and Ozempic, uses the work by mimicking the intestinal hormone called glucagon-like peptide-1 (GLP-1), so the technical term is GLP-1 receptor It's an agonist. This drug was first used to treat type 2 diabetes, but to reduce appetite, Wegovy is also approved for weight loss 8 countries. Semaglutide also offers tips to help with an extraordinary number of medical conditions.

Regarding alcohol use, there was a 2024 survey that 84,000 people injected Ozempic or Wegovy because of a lower risk of alcoholism. The results were promising and showed correlation rather than causality.

But now, Christian Hendershot The University of Southern California and his colleagues completed the first randomized clinical trial of the effects of semaglutide on alcohol use disorders.

Their trial involved 48 US people diagnosed with the condition, of which 34 were women and 14 were male. Half received a weekly low-dose injection of semaglutide for 9 weeks, and the rest received a placebo injection.

Semaglutide patients no longer consumed drinks per drinking session, reducing their weekly alcohol cravings compared to placebo drinks.

“There was no evidence of any significant adverse effects or safety concerns for drugs in this population. Overall, we found that it reduces the amount of alcohol people consume across several different drinking outcomes,” Hender said. Shot says.

“The results are promising.” Long Xu at Case Western Reserve University School of Medicine, Ohio. “Despite the small sample size, this randomized clinical trial highlights the therapeutic potential of semaglutide in the treatment of alcohol use disorders.”

ziyad al-aly At Washington University in St. Louis, Missouri, the study added ” yet another evidence of GLP-1RAS . [GLP-1 receptor agonists] It could help with addiction disorders.”

He needs greater research to answer questions about whether people will increase their drinking, especially when they leave semaglutide, particularly what the long-term impact is, and whether people will increase their drinking. He says. Bone and muscle mass.

The study should be treated as a promising first evidence, says Hendershot, but more research is needed. People should not start taking semaglutide due to alcohol problems, he says.

“This is the first study like this and people are excited about it, but we have approved effective drugs for alcohol use disorders, so more research has been conducted. Until now, people are encouraged to pursue and approve the existing medicines there right now,” says Hendershot.

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Source: www.newscientist.com

Chips linked with light could speed up AI training while reducing energy consumption.

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IBM optical module prototype for connecting chips with optical fibers

IBM’s Ryan Rabin

Fiber optic technology helps chips communicate with each other at the speed of light, allowing them to transmit 80 times more information than using traditional electrical connections. This could significantly reduce the training time required for large-scale artificial intelligence models from months to weeks, while also reducing data center energy and emissions costs.

Most cutting-edge computer chips still communicate using electrical signals transmitted over copper wires. But as the tech industry rushes to train AI models at scale, a process that requires networks of AI superchips to transfer large amounts of data, companies are using fiber optic speed-of-light communications to link chips together. I am very passionate about this.

This technology is not new. The Internet already relies on undersea fiber-optic cables that stretch thousands of kilometers between continents. But to transmit data between fingernail-sized chips, companies need to connect as many hair-thin optical fibers as possible to the end of each chip.

“As everyone knows, the best communication technology is fiber optics. That’s why fiber optics is used everywhere for long-distance communications.” Mukesh Khare A preview of the technology was given at a press conference at IBM Research. “This co-packaged optical innovation essentially brings the power of fiber optics to the chip itself.”

Khare and his colleagues have developed an optical module that allows chipmakers to add six times more optical fibers to the edge of a chip than with current technology. This module uses a structure called an optical waveguide to connect 51 optical fibers per millimeter. It also prevents optical signals from one fiber from interfering with adjacent fibers.

“What IBM has really done here is take advantage of all of its materials and packaging technology, its history of leadership in that field, to truly break down the way waveguides can be used to achieve high-density optical fiber. “It’s about doing it,” he says. dan hutchison at TechInsights, a semiconductor technology research company headquartered in Canada. “For me, when I saw this, it was a big step forward.”

The result is enhanced chip-to-chip communication, potentially allowing AI developers to train large language models in less than three weeks instead of three months. Switching from wires to fiber optics for chip communications could also mean cutting energy costs for training such AI models by a factor of five.

IBM has already put its optical modules through stress tests that include high humidity and temperatures ranging from -40°C (-40°F) to 125°C (257°F). Hutcheson expects large semiconductor manufacturing companies may be interested in licensing the technology.

“We are in the early days of all of this, but semiconductor technology is the hottest area right now in terms of high-performance computing and AI technology,” he says.

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  • artificial intelligence/
  • computing

Source: www.newscientist.com

The Impact of AI Monitoring on Reducing Stillbirths and Neonatal Deaths at a Clinic in Malawi

WEllen Kafamtengo felt a sharp pain in her lower abdomen and thought she might be going into labor. It was the ninth month of her first pregnancy, but she wasn’t taking any chances. With the help of her mother, the 18-year-old took a motorbike taxi and raced to a hospital in Malawi’s capital Lilongwe, a 20-minute drive away.

At Area 25 Health Center, she was told it was a false alarm and taken to the maternity ward. But when a routine ultrasound reveals that the baby is much smaller than expected at this stage of pregnancy, things quickly escalate, leading to suffocation, a condition that limits blood flow and oxygen to the baby may cause.

In Malawi, approx. 19 out of 1,000 babies Death occurs during childbirth or within the first month of birth. Childbirth asphyxia is the leading cause of neonatal death in this country and can result in brain damage to newborns with long-term effects such as developmental delays and cerebral palsy.

Doctors reclassified Ms Kafamtengo, who was expected to have a normal delivery, as a high-risk patient. Further tests using AI-powered fetal monitoring software revealed that the baby’s heart rate was slow. Stress tests revealed that the baby would not survive delivery.




Chikondi Chiweza, head of maternal and child care at Area 25 Health Center in Lilongwe, said: Photo: Provided by Halma plc

Chikondi Chiweza, the hospital’s head of maternal and child care, knew she had less than 30 minutes to deliver Kafamtengo’s baby by caesarean section. Having delivered thousands of babies in some of the city’s busiest public hospitals, she was well aware of how quickly a baby’s chances of survival can change during delivery.

Chiweza, who gave birth to Kafamtengo’s baby healthy, says the fetal monitoring program has made a huge difference to hospital births.

“[In Kaphamtengo’s case]we wouldn’t have realized what we did until later or as a stillborn baby,” she says.

Software donated by a birth safety technology company Perigen Through a partnership with the Malawi Ministry of Health, Texas Children’s Hospitaltracks your baby’s vital signs during delivery, giving clinicians early warning of abnormalities.
Since it began using the system three years ago, the number of stillbirths and neonatal deaths at the center has fallen by 82%. It is the only hospital in the country that has introduced this technology.

“The period around birth is the most dangerous for mothers and babies,” says Jeffrey Wilkinson, an obstetrician at Texas Children’s Hospital who leads the program. “Most deaths can be prevented by ensuring the baby’s safety during the birth process.”

AI monitoring systems require less time, equipment, and skilled staff than traditional fetal monitoring methods, making them essential for hospitals in low-income countries such as Malawi, which face severe health worker shortages. Routine fetal monitoring often relies on a doctor performing routine tests. This means that while the AI-assisted program provides continuous, real-time monitoring, important information may be missed during the interval. Traditional tests also require doctors to interpret raw data from various devices, which can be time-consuming and error-prone.

Area 25’s maternity ward handles approximately 8,000 births annually with a staff of 80 physicians. While only about 10% are trained to perform traditional electronic monitoring, most can detect abnormalities using AI software, helping doctors recognize higher-risk or more complicated births. Masu. Hospital staff also say that the use of AI has standardized key aspects of obstetric care in the clinic, such as interpreting fetal health status and deciding when to intervene.

Kafamutengo, who is excited to become a new mother, believes that doctors’ intervention may have saved her baby’s life. “They realized early enough that my baby was suffering and were able to take action,” she said as she held her son, Justice.

Doctors at the hospital hope the technology will be introduced to other hospitals in Malawi and across Africa.

“AI technology is being used in many fields, and saving the lives of babies is no exception,” Chiweza said. “We can really close the gap in the quality of care available to underserved populations.”

Source: www.theguardian.com

Reducing arm fat decreases dementia risk by 18%

It is widely known that excess body fat can lead to health issues like heart disease and diabetes. However, recent research has found a correlation between fat distribution in the arms and abdomen and the risk of developing dementia.

Dementia, a group of neurodegenerative disorders that includes Alzheimer’s disease, is on the rise globally. By 2050, it is projected that 139 million people worldwide will be affected. In the UK, it is estimated that one in three people born currently may develop dementia.


The causes of dementia are complex and not fully understood. However, a study published in the Journal of Neurology suggests that having high levels of body fat in the arms and abdomen can significantly increase the likelihood of developing neurodegenerative diseases like dementia.

The study involved over 400,000 participants, of whom a subset developed neurodegenerative diseases. After considering other factors like high blood pressure, smoking, and diabetes, the researchers found that individuals with higher levels of abdominal and arm fat had an increased risk of developing these conditions.

The researchers also found that greater muscle strength was associated with a lower risk of disease. They suggest that targeted interventions to reduce abdominal and arm fat may be more effective in preventing neurodegeneration than general weight management.

Further research is needed to fully understand how body composition affects overall health outcomes. The team plans to investigate the impact of body composition on other health issues like heart failure in the future.


About our experts

Xu Shishi Dr. Xu is a clinical physician specializing in endocrinology and metabolism at West China Hospital of Sichuan University, China. With a background in epidemiology and evidence-based research, his research interests include metabolic diseases and large-scale population cohort data analysis.

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Source: www.sciencefocus.com

Paris Olympics to showcase city’s shift towards reducing air pollution by limiting car usage.

Paris, the host city for the 2024 Summer Olympics, has undergone a significant transformation in recent years. The city has made efforts to become greener by reducing its reliance on cars, setting an example for cities around the world.

Under the leadership of Mayor Anne Hidalgo, Paris has enacted several changes to promote sustainability. Over 100 roads have been closed to automobiles, parking fees have tripled, SUVs have been restricted, around 50,000 parking spaces have been removed, and over 1,300 kilometers of bike lanes have been built.

These efforts have resulted in a 40% reduction in air pollution, according to city officials. Hidalgo expressed that Paris would end its dependency on cars through disruptive changes.

Although European cities like Paris have been leading the way in reducing car use, similar reforms in the U.S. have been slow to materialize. The American infrastructure has historically been built around cars, making it challenging to transition to alternative modes of transportation.

The environmental reforms in Paris have garnered support from residents like Louise Kraustl, who believes that fewer cars and more walking and cycling make the city safer and less polluted. Inspired by the concept of the “15-minute city,” Paris aims to create pedestrian and bike-friendly neighborhoods where daily necessities are within easy reach.

While some cities in the U.S. have made progress in promoting biking and public transport, car dependency remains prevalent. Despite the challenges, experts emphasize the importance of reducing transportation emissions to combat climate change and improve air quality.

Paris’ efforts to prioritize sustainable urban planning serve as a model for other cities to follow. As cities worldwide grapple with the effects of climate change, the need for transportation reform becomes increasingly urgent.

The upcoming elections in Paris will be crucial in determining the city’s continued commitment to reducing car use and combating climate change.

Source: www.nbcnews.com

Adopting a low FODMAP diet may be more effective than medication in reducing symptoms of irritable bowel syndrome

Eating less of some types of foods and more of others may ease irritable bowel syndrome

Aamrya/Getty Images

Two types of diets are more effective at treating irritable bowel syndrome (IBS) than drugs, a trial has found.

One diet was designed to be low in FODMAPs, a group of carbohydrates similar to sugars found in dairy products, wheat, and certain fruits and vegetables. The second, less common approach used for IBS is an adaptation of a low-carbohydrate diet that is high in fiber and low in other types of carbohydrates, such as sugar and starch.

In a randomized trial, both diets showed better symptom improvement than standard drug treatment after four weeks.

IBS can cause mysterious symptoms such as diarrhea, constipation, bloating, and abdominal pain that increase or decrease over time. The underlying cause of this condition is unknown.

The usual advice is to avoid common triggers such as caffeine, alcohol and spicy foods. Symptomatic treatments such as laxatives for constipation and drug therapy for diarrhea may be given.

If these measures don’t work, you may want to consider cutting back on foods high in FODMAPs. FODMAPs tend not to be digested until they reach the colon, which is why they are thought to cause bloating and diarrhea. This encourages the colon to retain water, and when the molecules are consumed by bacteria, gas is produced and causes bloating.

Sanna Niebacka Researchers from the University of Gothenburg in Sweden wanted to find out how a regular low-FODMAP diet compared to an alternative approach: high in fiber but low in carbohydrates. In practice, this means eating high-fat, high-protein foods such as meat and dairy products, and sources of fiber include nuts, seeds, beans, and vegetables such as cabbage.

The research team asked around 300 people with IBS to use one of three approaches depending on their symptoms: take medication or adopt one of two diets. The diet provided people with free grocery delivery, as well as detailed meal plans and recipes.

After one month, 76% of the low-FODMAP group reported a significant reduction in symptoms, compared with 71% of the low-carbohydrate diet group and 58% of the drug treatment group.

The big surprise was that a low-carbohydrate, high-fiber diet that didn’t exclude FODMAP-containing foods was about as effective as a low-FODMAP approach, Nybacka says. “We can’t answer any questions as to why. It appears that altering carbohydrate content and reducing FODMAP intake may be beneficial.”

but hazel everitt Researchers at the University of Southampton in the UK say the trial would have been more informative if it had lasted longer. “The problem with many of the IBS diets that have been proposed is that they are very difficult to stick to long-term,” she says.

Participants were followed for up to six months, but during the last five months participants who were initially offered drug treatment were also given dietary advice.

Niebacka says one potential problem with the low-carbohydrate, high-fiber diet is that this group of people had slightly elevated blood cholesterol levels. Therefore, you should seek your doctor’s advice before adopting this diet, she says.

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Source: www.newscientist.com

New Study Identifies the Most Effective Diet for Reducing Loud Snoring

Dealing with snoring can be a bothersome experience for everyone involved, whether it’s falling asleep on a public bus or waking a loved one. Researchers may have found the best diet to combat this issue.

Obstructive sleep apnea (OSA) is a common condition that puts people at risk for high blood pressure, stroke, heart disease, and type 2 diabetes. This is because OSA causes multiple disruptions during sleep due to loud snoring and interruptions in breathing.

The solution may lie in a diet rich in vegetables, fruits, and whole grains, as suggested by a new study published in the journal ERJ Open Research. This diet may help prevent or treat OSA.

In order to test this theory, researchers at Flinders University in Adelaide, Australia, used data from 14,210 participants in the US National Health and Nutrition Examination Survey. Participants were asked to list everything they had consumed in the past 24 hours, and the research team categorized their responses into three dietary patterns: a healthy plant-based diet, an unhealthy plant-based diet, and a diet high in animal products.

The “unhealthy” plant-based diet included high amounts of refined carbohydrates, potatoes, sugary drinks, sweets, desserts, and salty foods.

Additionally, participants completed a sleep questionnaire to determine the likelihood of having OSA. The researchers found that people with diets high in plant foods were 19% less likely to suffer from snoring caused by OSA. On the other hand, those who consumed an unhealthy plant-based diet were 22% more likely to have OSA.

Researchers believe that a healthy plant-based diet may be important due to its anti-inflammatory components and antioxidants, which can impact fat mass, inflammation, and muscle tone, thereby affecting a person’s OSA risk.

Dr. Johannes Melak, the chief researcher, emphasized that diet quality is important in managing the risk of OSA, and that a healthy plant-based diet may reduce inflammation and obesity.

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Source: www.sciencefocus.com

Probiotics found effective in reducing fatigue and memory loss related to prolonged COVID-19 infection

Probiotics, illustration of live microorganisms that can affect intestinal bacteria

ART-ur/Shutterstock

A daily cocktail of prebiotics and probiotics can help reduce fatigue, memory, and symptoms in people with long-term COVID-19 (symptoms that persist for months or years after being infected with COVID-19). May be useful in treating gastrointestinal complaints.

Although little is understood about long-term coronavirus infections, previous research has shown that people with the disease have lower levels of certain gut microbes than those without. Masu. In particular, they lack gut bacteria that produce compounds called short-chain fatty acids that regulate immune responses.

Siu Ng and his colleagues at the Chinese University of Hong Kong have formulated a mixture that boosts the production of short-chain fatty acids. The product, called SIM01, contained three probiotics (live bacterial strains) and three prebiotics (compounds that help the growth of beneficial gut bacteria).

They distributed this cocktail to 232 adults. Another group of 231 adults took a mixture containing starch and low-dose vitamin C. Both mixtures were taken twice a day for 6 months. All participants were residents of Hong Kong, had previously tested positive for COVID-19, and met the U.S. Centers for Disease Control and Prevention’s criteria for long-term COVID-19 infection.

Researchers used a questionnaire to assess 14 long-term COVID-19 symptoms in participants before treatment began and after treatment ended. At the end of the trial, people who received SIM01 were likely to experience relief from five long-term coronavirus symptoms: fatigue, memory loss, difficulty concentrating, general unwellness, and gastrointestinal upset. It was found to be about 2 to 2.5 times higher on average. The research team also found no serious side effects from the treatment.

Analysis of fecal samples taken before and after the trial revealed that SIM01 increases gut microbial diversity and promotes the growth of beneficial gut bacteria, Ng said. Therefore, she says, it could be useful in treating other conditions that are associated with disruption of the gut microbiome, such as chronic fatigue syndrome.

However, it is unclear how these changes in the gut reduce the symptoms of long-term coronavirus infection. timothy sampson At Emory University in Georgia. “It makes sense that the microbiome has the ability to mediate immune responses, but… [immune system] What is actually at the root of [long covid] You get symptoms,” he says.

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Source: www.newscientist.com