The Evolution of Sperm: Tracing Its Origins Before Multicellular Animals

The origins of the sperm swimming mechanism date back to ancient times.

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The evolutionary roots of sperm can be traced to the unicellular forerunners of all existing animals.

Nearly all animals go through a unicellular phase in their life cycle, which involves two forms of sex cells, or gametes. Eggs are sizeable cells that hold genetic information and the nutrients necessary for early development, while sperm transport genetic material from one organism to another to fertilize eggs and create new life.

“Sperms play a crucial role in the process that allows life to be transmitted from generation to generation,” states Arthur Matt from Cambridge University. “It carries the legacy of over 700 million years of evolutionary history and is likely linked to the origins of animals themselves. Our aim was to explore this extensive evolutionary narrative to understand the origins of sperm.”

Matt and his team utilized an open science dataset containing information about sperm proteins from 32 animal species, including humans. They combined this data with the genomes of 62 organisms, including various related single-cell groups, to track the evolution of sperm across different animal lineages.

The research revealed a “sperm toolkit” comprising about 300 gene families that make up the last universal common sperm core genome.


“We have now identified numerous significant advancements in sperm mechanisms occurring long before multicellular animals emerged, even before the sperm themselves,” explains Matt.

This indicates that the sperm mechanics, represented by a “flagellum that propels a single cell,” were already evolving prior to the development of multicellular organisms.

Thus, our ancient progenitors were once all single-celled oceanic swimmers, and the sperm toolkit was present in our earliest swimming unicellular predecessors long before the advent of animals.

“Animals evolved multicellularity and cellular differentiation, but they did not create sperm from nothing. They repurposed the body structure of their swimming forebears as the foundation for sperm,” states Matt. “In essence, sperm are not a novel creation of multicellular organisms but are constructed upon the designs of a single-celled organism repurposed for reproduction.”

The study also indicated that the significant technological developments leading to the vast variety of current sperm primarily affected the cell heads, while the tails have remained largely constant since their common ancestor.

According to the research team members, fertilization can occur in various manners, with some sperm reaching the egg within the body, while others swim in open waters, notes Adria Leboeuf, also from the University of Cambridge. “Finding eggs in these different settings presents unique challenges and requires specialized machinery,” she explains. “However, the tail remains well-preserved since it must be capable of swimming in all environments.”

“This illustrates how evolution can modify existing structures instead of creating mechanisms from scratch,” says Jenny Graves, from La Trobe University in Melbourne, Australia.

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Source: www.newscientist.com

Sperm Are Self-Serving – Just Like Us.

Selfish behavior is alarmingly prevalent in biological contexts. A recent study underscores this, illustrating how genetic mutations accumulate in the sperm of older men. Research indicates that as men age, new stem cells increase the likelihood of carrying disease-related mutations, potentially affecting up to 5% of their sperm by the time they reach 70.

This discovery highlights not only the advantages of having children at a younger age but also the indifferent nature of mutated stem cells, which do not consider the consequences for future offspring as long as their genetic material is passed on. This serves as a potent reminder that the notion of “selfish genes” remains a foundational concept in evolutionary biology. Genes prioritize their own survival over any altruistic intentions, continually bringing discussions back to genetic selection, contrary to the idea of “survival of the fittest.”

The ongoing debate is weary and centers around whether evolution through natural selection favors cooperation or promotes competitive and ruthless organisms that prioritize reproduction above all else. Over the past century, numerous biologists have debated this issue, labeling differing perspectives on group versus individual selection. These distinctions fundamentally shape our understanding of the natural world and our role within it.

The divide between these views has consistently straddled ideological lines. Earlier animal behaviorists believed that organisms act for the benefit of their species. The idea was that individual survival is advantageous for the entire group, creating a potential contributor to the continuation of humanity. Homo sapiens can achieve this common goal through mutual assistance.

However, as highlighted by key biologists from Ronald Fisher to contemporary thinkers like Richard Dawkins, organisms that accept help from others without reciprocating consistently outperform those that give help. Those that disrupt group dynamics tend to position themselves for greater success—as long as their impact isn’t so destructive that it eliminates all competition.

From an evolutionary standpoint, the optimal strategy for individuals is to encourage cooperation while withholding it from others—ideally, without detection. Instead of fostering good and altruistic qualities, cooperation can create an environment where competitive and exploitative behaviors thrive unnoticed.

The issue of destruction undermines populations, whether they are gametes, bacteria, animals, or humans. Stem cells, which reproduce at the expense of a host’s descendants, are indifferent to whether their proliferation harms future generations. The welfare of both the host and its species is irrelevant.

This logic extends to human societies, both ancient and modern. Individuals in power—often older men—tend to monopolize resources and frequently choose younger women as partners. Given the adverse effects of older men on fertility, it’s challenging to take the group selection model seriously in light of new findings regarding sperm.

Crucially, these unsettling realities about our biological roots do not dictate our behavior today. We should strive for mutual aid and not take it for granted. Recognizing our inherent selfish tendencies at every biological level is the initial step toward overcoming them.

Jonathan R. Goodman is the author of Invisible Rivals: How We Evolved to Compete in a Cooperative World

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Source: www.newscientist.com

Man confesses to selling teeth and bones of sperm whales

A South Carolina man admitted guilt on Thursday for bringing in and selling sperm whale teeth and bones from four countries in the United States, according to federal prosecutors.

Lauren H. Deloha, 69, of St. Helena, South Carolina, pleaded guilty to violating the Lacy Act and the Marine Mammal Protection Act by importing and selling sperm whale parts. The US Attorney’s Office in South Carolina reported this.

Deloach is said to have imported sperm teeth and bones into South Carolina from July 2022 to September 2024, including at least 30 shipments from Australia, Latvia, Norway, and Ukraine, as revealed in court documents and statements made in court.

He allegedly sold around $18,000 worth of at least 85 pieces on eBay, falsely labeling them as “plastic” to evade detection by customs officials, according to prosecutors.

Authorities mentioned that they confiscated about $20,000 worth of sperm whale parts while searching his residence.

It remains unclear how Deloach acquired these items and who purchased them from him. Teeth and bones are sought after for use in artworks like sculptures, prosecutors stated.

Sperm whales, the largest toothed whales, inhabit deep waters worldwide, from the equator to the edges of ice in the Arctic and Antarctic, according to the National Oceanic and Atmospheric Administration. Females can grow up to 40 feet long, while males can reach up to 52 feet long, as per the agency.

Sperm whales have been safeguarded since 1970 under the Endangered Species Act and the International Treaty on Endangered Species of Wild Fauna and Flora. The Lacey Act criminalizes the illegal sale of wildlife that was imported illegally, prosecutors mentioned.

“Illegal wildlife trafficking is a multi-billion dollar global enterprise, with animals and fuels protecting organized crime,” stated Brooke B. Andrews, acting US attorney for South Carolina. “We will uphold the Lacey Act and the Marine Mammal Protection Act. Vulnerable species like sperm whales have been slaughtered for profit.”

Deloach’s attorney, Nathan S. Williams, mentioned in a statement on Sunday that Deloach “regretted his actions and took responsibility for them.”

Deloha faces a maximum of five years in prison, a $250,000 fine for felony Lacey Act violations, and up to one year in prison for misdemeanor violations of the Marine Mammal Protection Act.

This incident was the latest involving protected wildlife.

In February, a California couple reached a plea agreement in Butte County, California. They were caught by wildlife officers smuggling mountain lion trophies and turtle skulls in their carry-on bags, breaching fish and game laws. The California Department of Fish and Wildlife stated.

Source: www.nytimes.com

Uncovering the Truth Behind Earth’s Crisis of Declining Sperm Counts

With the abundance of news stories, one might believe that humanity is on a path to self-destruction due to pollution, microplastics, and harmful chemicals. Reports of decreasing sperm counts have led to discussions about a possible “Spermageddon,” with politicians even considering incentivizing women to have children (source).

However, after speaking with experts like Professor Alan Pacey, a male infertility researcher, and Professor Sarah Harper, director of the Oxford Institute of Population Ageing, it seems that while there is reason to be concerned, we are not currently in a crisis.

Why are some people concerned about “Spermageddon”?

The concern dates back to a study from 1974 that showed a decrease in sperm counts among American men compared to the data from the 1950s (source). While various factors like climate change, genetic defects, and microplastics have been suggested as causes for declining sperm counts, not all experts are convinced about the severity of the issue.

Recent studies, including those conducted in Denmark, have not shown significant declines in sperm quality, leading to doubts about the extent of the problem. While concerns about microplastics and chemicals are valid, they may not be directly linked to infertility as some believe.

Recent research published in the journal Nature also suggests that semen quality worldwide may not be declining significantly.

Is global infertility on the rise?

While birth rates are indeed falling, experts argue that there is no concrete evidence of a widespread increase in infertility. Factors like delayed childbearing, improved access to fertility treatments, and reduced stigma around infertility may be contributing to more people seeking assistance at fertility clinics.

Why are populations declining in many areas?

The declining birth rates in countries like South Korea, China, and the United States are influenced by various factors, including economic growth and changing societal norms. While it may seem like an “infertility epidemic,” some experts see it as a demographic outcome of broader trends.

Should we be concerned?

Experts have differing perspectives on the issue. While some, like Professor Harper, believe that falling birth rates are not a cause for alarm, others, like Professor Pacey, are concerned about the barriers to fertility treatment and the impact on individuals facing infertility. Both emphasize the need for a nuanced approach to addressing the complex factors affecting fertility rates.

About our experts

Professor Alan Pacey MBE is a renowned researcher in male fertility and sperm biology at the University of Manchester, with over 30 years of experience in the field.

Professor Sarah Harper CBE is a gerontology expert at the University of Oxford, focusing on population aging and fertility trends.

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Source: www.sciencefocus.com

Study reveals sperm whale communication is more intricate than previously believed

Sperm whale (physeter macrocephalus) They are highly social mammals that use clicks to communicate. New research shows that, just like in human language, they can combine and coordinate different clicks and rhythms to create complex calls.

Sperm whale (physeter macrocephalus). Image credit: Gabriel Barathieu / CC BY-SA 2.0 Certificate.

Communication is important for social animals to make group decisions and coordinate collaborative tasks such as foraging and raising children.

Sperm whales are social mammals that communicate with each other by clicking repeatedly.

Little else is known about sperm whales' communication systems, although some of their clicks have previously been shown to communicate their identity.

“Cetaceans are an important group for studying evolution and the development of sophisticated communication systems,” said Pratyusha Sharma, a researcher at the Massachusetts Institute of Technology (MIT), and colleagues.

“Among cetaceans, long-term observational studies of sperm whales describe both a culturally defined, multilayered matrilineal society and a socially transmitted communication system.”

“Sperm whales are known for their complex social and foraging behaviors, as well as their collective decision-making.”

“They communicate using codas, stereotypical sequences of three to 40 broadband clicks. Codas are exchanged when whales interact with each other and during long, deep dives foraging. .”

For the study, the authors Dominican Sperm Whale Projectthe largest repository of sperm whale data.

They analyzed the records of about 60 different whales from the eastern Caribbean sperm whale clan and used them to define a “sperm whale phonetic alphabet” of click combinations from this clan's records.

They discovered that whales' communication systems are more complex and have greater information-transfer capabilities than previously thought.

We found that the combination and structure of the generated click sequences depended on the context of the individual's conversation.

Scientists also identified a “combinatorial structure” in whale language. Whales can combine and coordinate different clicks and rhythms to create complex vocalizations, similar to human language.

“Although the function and meaning of the click combinations are still unknown, the sperm whale language could potentially express a large number of meanings,” the researchers said.

Their paper It was published in the magazine nature communications.

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P. Sharma other. 2024. Contextual and combinatorial structure in sperm whale calls. Nat Commune 15, 3617; doi: 10.1038/s41467-024-47221-8

Source: www.sci.news

Ultrasound treatment activates sluggish sperm movement

Sperm that don't move fast enough have a hard time reaching the egg and can cause fertility problems.

Alexei Kotelnikov / Alamy

Laboratory research has revealed that applying ultrasound to immobile sperm causes it to move. If sperm does not move properly, it becomes difficult for them to reach the egg, which is a major cause of infertility. With further research, this technology could help improve the success rate of in vitro fertilization (IVF).

Previous research suggests that: High frequency ultrasound increases sperm motility. However, the study did not involve isolating the sperm to assess which individual cells would be beneficial, allowing doctors to find the best cells to use in fertility treatments.

In the latest research, Ali Vafaie The researchers, from Monash University in Melbourne, Australia, classified 50 semen samples into three groups (fast, slow, and stationary) according to sperm motility, based on guidelines for assessing swimming speed.

After separating individual sperm cells from semen samples, the researchers measured the motility of the cells before and after exposure to ultrasound waves with a power of 800 megawatts and a frequency of 40 megahertz.

After 20 seconds of ultrasound, 59 percent of the immobile sperm slowed down, and some started swimming rapidly. Changes in sperm motility peaked at an increase of 266%.

Overall, immotile sperm made up 36% of the samples at the start of the study, but this decreased to just 10% after treatment. It is unclear how long the increase in migration lasted.

Researchers believe that exposure to ultrasound improves dysfunction in sperm's mitochondria, the cells' powerhouses, contributing to increased motility.

This approach could increase the success rate of in vitro fertilization, which requires motile sperm for conception, and could avoid the need for multiple costly surgeries.

But first, Vafai says, the research group will need to test the effectiveness of the approach on sperm, particularly in people experiencing infertility due to reduced sperm mobility. Scientists also need to assess whether it is safe to create embryos from sperm exposed to ultrasound, he says.

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Source: www.newscientist.com

Researchers Are Investigating the Decline in Sperm Counts Globally

The year was 1974. While newspaper columnists were busy talking about the development of in vitro fertilization and the possibility of “test tube babies,” the surprising discovery about male fertility completely escaped their notice.

Two doctors, Iowa State CM Kinloch Nelson and Raymond Bunge, compared semen samples from that time with historical data. Dramatic changes in a man’s sperm count Over the past 20 years. In 1951, one milliliter of semen contained 107 million sperm. By the 1970s, that number had fallen by more than 50% to just 48 million people. The average volume of semen per ejaculation also decreased.

By the 1990s, the problem began to receive considerable scientific attention, although some researchers remained skeptical. They blamed differences in technology or the fact that most of the research involved men already undergoing treatment for infertility. Those doubts are now diminishing. “There is a tremendous amount of scientific evidence showing this decline,” he says. Albert Salas-Huetos at the University of Rovira y Virgili, Spain.

For researchers like Salas-Huetos, the big question is no longer whether this so-called “Spermageddon” is really happening, but why and what to do about it. Research is beginning to uncover environmental toxins that may be the culprit, as well as other lifestyle factors that contribute to the problem. With a better idea of the prime suspects, we may finally be able to put the brakes on this trend, or even reverse it.

decreased sperm count

around the world 1 in 6 people have problems…

Source: www.newscientist.com