First-Time Detection of Ammonia-Containing Compounds in Europe: Key Findings and Implications

A recent analysis of archival data from NASA’s Galileo spacecraft’s Near Infrared Mapping Spectrometer (NIMS) has uncovered the first evidence of ammonia-containing compounds on Jupiter’s icy moon Europa. This groundbreaking discovery provides vital clues about Europa’s subsurface ocean and recent geological activity.



This composite image highlights red pixels indicating sites on Europa where ammonia compounds were detected; purple indicates areas without detection. Image credit: NASA/JPL-Caltech.

“The detection of ammonia (NH3) is significant for understanding not only the geology of icy bodies in our solar system but also their potential habitability and astrobiological relevance,” stated Dr. Al Emran, a researcher at NASA’s Jet Propulsion Laboratory.

“On Europa, the identification of ammonia or ammoniated species is crucial for revealing ocean chemistry, assessing habitability, and reconstructing the moon’s early atmosphere.”

Ammonia functions as an antifreeze agent, reducing the freezing point of liquid water by up to 100 K, which may help preserve underground oceans in icy celestial bodies.

Though it’s unclear if Europa’s underground ocean is directly linked to the surface, detecting ammonia compounds could imply such a connection, given that these materials are unstable under cosmic radiation.

In a new study published in Planetary Science Journal, Dr. Emran reported detecting a distinct ammonia absorption feature at 2.20 microns in Europa’s near-infrared spectrum.

This signal was confirmed through observations from Galileo’s NIMS instrument, which examined Europa during a flyby in the 1990s.

Ammonia hydrate and ammonium chloride are likely responsible for the detected spectral features.

The instability of ammonia under strong cosmic radiation highlights the importance of its presence on Europa’s surface.

The discovery of ammonia-containing materials suggests they may have originated from Europa’s subsurface ocean or shallow subsurface during the moon’s geologically recent past, possibly through cryovolcanism or similar processes.

This analysis also hints at significant implications for Europa’s internal structure.

The presence of ammoniated compounds aligns with a subsurface ocean characterized by a thinner, chemically reduced ice shell with a higher pH.

Ammonia’s antifreeze properties are essential, as they lower the freezing point of water ice, allowing for the maintenance of a liquid ocean beneath Europa’s icy shell.

“Faint signals of ammonia have been detected near fractures in the moon’s frozen surface, where liquid water, rich in dissolved ammonia compounds, is expected to ascend,” Emran noted.

“These compounds might have traversed the surface due to recent geologically active cryovolcanic events.”

Ammonia’s presence, which significantly lowers the freezing point of water, acts as a natural antifreeze.

Similar ammonia-bearing species have been identified on other icy objects in the outer solar system, including Pluto, Charon, certain moons of Uranus, and Saturn’s moon Enceladus. However, earlier attempts to confirm ammonia’s presence on Europa produced inconclusive results.

“The identification of ammonia-containing compounds in this research marks the first evidence of nitrogen-based species on Europa, a finding of considerable astrobiological importance due to nitrogen’s fundamental role in life’s molecular structure,” Emran concluded.

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A. Emran. 2026. NH3 detection at Europa’s 2.2 μm absorption band. Planetary Science Journal 6,255; doi: 10.3847/PSJ/ae1291

Source: www.sci.news

L-Theanine: Can Matcha and Other Tea Compounds Alleviate Anxiety and Enhance Focus?

Black and green teas including matcha exhibit various levels of L-theanine

inna finkova / alamy stock photos

L-theanine is a naturally occurring amino acid found in tea leaves. Its association with the calming effects of tea dates back to the 1940s, and it is now available as a supplement aimed at alleviating stress, enhancing focus, and improving sleep quality. Although studies on its effectiveness are still somewhat limited, there are intriguing insights that may suggest advantages for brain health, particularly for those experiencing anxiety.

What are the potential benefits of L-theanine?

Research on L-theanine shows promise but remains in the preliminary stages. “The research is limited, the sample sizes are small, and the results can vary,” says Crystal Haskell-Ramsay from Northumbria University, UK.

Nonetheless, findings from minor trials indicate that L-theanine may help reduce blood pressure during attention-demanding tasks, and during stressful periods, it might mitigate heart rate surges associated with cortisol, the stress hormone. Some evidence also points to its potential for enhancing relaxation and concentration.

How does L-theanine influence the brain?

Upon entering the bloodstream through the intestine, L-theanine is capable of crossing the blood-brain barrier. It shares similarities with brain glutamic acid and GABA, neurotransmitters responsible for regulating signals in the brain. Studies on rodents suggest that L-theanine may elevate levels of dopamine and serotonin, chemicals linked to various cognitive functions, including mood and reward.

Furthermore, L-theanine is known to increase alpha brain wave activity, which is associated with a calm yet alert state. “When you close your eyes, alpha waves increase instantly,” remarks Manuel Gomez Ramirez from Rochester University in New York.

Does it contribute positively to mood and well-being?

Generally, heightened alpha brain wave activity can enable better focus and diminish distractions, and L-theanine may amplify this effect. “The greater the alpha activity, the better the brain coordinates its surroundings,” explains Gomez Ramirez. The synergy between caffeine and L-theanine likely enhances this effect.

The influence of L-theanine on alpha waves appears to be more pronounced in individuals who are already experiencing anxiety. Studies on stressed rodents reveal that L-theanine can affect dopamine and serotonin levels in certain brain regions, correlating with a reduction in symptoms akin to depression. However, human studies yield inconsistent results, with some indicating a lack of efficacy for generalized anxiety disorder, while others report reductions in stress and anxiety levels.

If L-theanine alleviates anxiety, this could elucidate its benefits for sleep. A review found that it may help individuals fall asleep more swiftly and enhance their overall sleep quality.

Is there sufficient L-theanine in tea?

Teas, particularly green varieties like matcha, contain varying amounts of L-theanine, averaging between 5-40mg per cup. While this could provide a mild effect, most research studies utilize dosages around 200 mg, akin to those commonly found in supplements.

How robust is the evidence for L-theanine?

Many studies involve small participants, focus on short-term outcomes, and frequently test just single doses or limited supplementation periods. “There’s certainly potential, but further work is required in this area,” states Amanda Bluman from the University of Canberra in Australia.

A noteworthy complication is that L-theanine is often studied in conjunction with other components, which complicates the interpretation of results. “It’s challenging to ascertain whether L-theanine is solely responsible,” mentions Haskell-Ramsay. “Disentangling which elements are effective is problematic.”

Moreover, Haskell-Ramsay cautions, “Many people take it consistently for long durations, so long-term data is lacking.”

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Source: www.newscientist.com

Compounds in Chocolate and Tea Could Help Reduce Blood Pressure

A naturally occurring compound known as flavan-3-ol, present in cocoa, tea, apples, and grapes, has been shown to enhance blood pressure and vascular health, according to a recent meta-analysis conducted by researchers at the University of Surrey involving 145 prior studies.



Flavan-3-OL-rich foods and supplements, similar to medications, are regularly consumed, particularly by those with high blood pressure, to help lower blood pressure. Image credit: Lagou et al., doi: 10.1093/eurjpc/zwaf173.

“Flavan-3-ol found in cocoa, tea, and various fruits shows potential in enhancing blood pressure and vascular function, but is not yet utilized for cardiovascular prevention,” stated Professor Christian Heiss, the lead author of the study from the University of Surrey.

“Our meta-analysis evaluated how flavan-3-ol-rich interventions impact blood pressure and endothelial function.”

In the meta-analysis, the researchers examined data from 145 randomized controlled trials published between 1946 and 2024.

The findings indicated that regular intake of flavan-3-OLs could lead to reductions in blood pressure readings, particularly among individuals with elevated blood pressure or hypertension.

Some results showed that the average decrease in blood pressure was comparable to that produced by certain medications.

Additionally, flavan-3-ol was found to enhance endothelial function (the inner layer of blood vessels), which is crucial for overall cardiovascular health.

This improvement occurs independently of blood pressure changes, suggesting a broad positive impact on circulatory health.

“These results are promising for those seeking a simple way to manage blood pressure and support heart health through enjoyable dietary adjustments,” Professor Heiss added.

“Incorporating small amounts of commonly enjoyed foods such as tea, apples, dark chocolate, and cocoa powder into a balanced daily diet can provide beneficial flavan-3-ol levels.”

“While it should not replace prescribed medications or medical guidance, it can be a beneficial addition to a healthy lifestyle, particularly for individuals with high blood pressure, by incorporating flavan-3-ol-rich foods into their daily routine.”

“These encouraging findings warrant further research.”

A paper discussing the survey results has been published in the European Journal of Preventive Psychology.

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Vasiriki Ragou et al. Effect of flavan-3-OL on blood pressure and endothelial function in various populations: a systematic review and meta-analysis of randomized controlled trials. European Journal of Preventive Psychology Published online on March 24th, 2025. doi: 10.1093/eurjpc/zwaf173

Source: www.sci.news

Amino Acids, Salt, and Other Compounds Discovered in Asteroid Bennu Sample by Scientists

The asteroid Benne is believed to be made of tile BLE fragments from the body 4.5 billion years ago, which contains materials generated beyond Saturn, which is a separate object long ago. Destroyed by a collision. In two new papers, scientists include amino acids (including 14 out of 20 used in land biology), polygan aromatic hydrocarbons, ammonia and other compounds, and sodium carbonate, phosphate. It is reported to detect salt such as sulfate, sulfate, sulfate, and sulfate sulfate. Chloride is a Bennu sample delivered to the earth by NASA's OSIRIS-REX spacecraft in 2023.

This mosaic image of the asteroid Benne consists of 12 images collected by 15 miles (24 km) of OSIRIS-REX on December 2, 2018. Image Credit: NASA / NASA Godaddo Space Flight Center / Arizona University.

Dr. Nicky Fox, a semi -manager of the NASA headquarters science mission director, states:

“Asteroids provide time capsules to the history of our hometown planet, and Bennne's sample is extremely important to understand what our solar components exist before life begins on the earth.”

In the Bennu sample, researchers Found Amino Acid -Life on the Earth Used to produce proteins, 14- and all five nuclear foundations used by life on the earth, including a method of placing amino acids amino acids. Used to save and send genetic instructions to molecules. protein.

In addition, the very high existence of ammonia was detected. This is important for biology because it may react with formaldehyde detected in samples, form complex molecules such as amino acids and react in consideration of proper conditions.

When the amino acid is linked to a long chain, protein is created and almost all biological functions supply power.

These building blocks detected by the Bennu sample have previously been found on the outer rocks.

However, it supports the idea that identifying them with an unbalanced sample collected in the universe may be an important cause for the life of the entire solar system. I am.

Dr. Dany Gravin, a senior sample scientist at NASA's Godde Space Flight Center, states:

“That's why some of these new discoveries are not possible without sample return missions, close pollution control measures, and the precious curation and storage of this precious material from Benne.”

OSIRIS-REX View on the outside of sample collector. The asteroid sample material can be seen in the center of the right. Image credit: NASA / ERIKA Blumenfeld / Joseph AeberSold.

scientist It will be identified The traces of 11 salt minerals in the bene sample, which are formed as water containing dissolved salt, evaporate for a long period of time, leaving salt as solid crystals.

Similar salt water is detected or proposed throughout the solar system, including Dwarf Planet Ceres and Saturn's Moon Enkelladus.

“The discovery of these salt was a break -through in space research,” said Dr. Nick Timms, a researcher at Curtin University.

“I was surprised to identify the mineral haright, which is a sodium chloride. It is exactly the same salt as the salt that may be placed in the chip.”

“The mineral we discovered is formed from the evaporation of salt water, which is a bit similar to the salt sediment formed in Australia and the salt lake around the world.”

“By comparing with the mineral sequence of the salt lake on the earth, we can begin to imagine what the asteroid Bennne was, and provide instructions on ancient universe water activities.”

“OSIRIS-REX was a very successful mission,” said Dr. Jason Dworkin, the scientist of OSIRIS-REX, a researcher of NASA's Goddard Space Flight Center.

“OSIRIS-REX data adds a major brush stroke to photos of the solar system that may have life.”

“Why are we so far, not only to see the life on the earth, but it's a really appetite question.”

The survey results are displayed in two journals Natural astronomy And journal Nature

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DP gravin et al。 Asteroid (101955) Sil soluble organic matter with abundant ammonia and nitrogen in Benne sample. Nut asronReleased online on January 29, 2025. Doi: 10.1038/S41550-02472-9

TJ McCoy et al。 2025. An evaporated sequence from ancient salt water recorded in Bennne sample. Nature 637, 1072-1077; DOI: 10.1038/S41586-024-08495-6

Source: www.sci.news

Discovery of Metabolic Compounds that Control Appetite and Weight

Research has revealed a new metabolic pathway involving beta-hydroxybutyric acid (BHB). Previously known as a liver-produced fuel, BHB is now found to be attached to amino acids by the enzyme CNDP2. The most abundant BHB amino acid, N-β-hydroxybutyryl phenylalanine (BHB-Phe), can impact body weight and metabolism in animal models.



Beta-hydroxybutyric acid (BHB) is an abundant ketone body. All BHB metabolic pathways known to date involve the interconversion of BHB and primary energy intermediates. Moya Garzon others. BHB et al. identified a previously undescribed BHB secondary metabolic pathway via CNDP2-dependent enzymatic binding of BHB and free amino acids. Image credit: Moya-Garzon others., doi: 10.1016/j.cell.2024.10.032.

Mammals have developed intricate nutrient response pathways linking external energy sources with internal metabolic balance.

These pathways involve changes in cellular energy metabolites serving as both fuel sources and downstream regulators.

BHB, a ketone body, is a key example whose levels rise during low carbohydrate conditions like starvation, intermittent fasting, or ketogenic diet.

In a recent study, Professor Yong Xu of Baylor College of Medicine and team investigated how BHB-Phe, the most common BHB amino acid, affects eating habits and body weight in mice.

“Brain neuron groups regulate feeding behavior, so we mapped the brain to identify regions activated by BHB-Phe,” explained Professor Xu.

“BHB-Phe activated neural populations in the hypothalamus and brainstem, suppressing feeding and leading to weight loss.”

In contrast, mice lacking CNDP2 enzyme, deficient in BHB-Phe, ate more and gained weight.

Interestingly, CNDP2 also produces Lac-Phe, a compound discovered earlier by the research team.

“Lac-Phe from exercise can reduce food intake and obesity in mice,” added Professor Xu.

“But do Lac-Phe and BHB-Phe trigger effects by activating the same brain neurons?”

This discovery points to a possible disruption of the BHB-Phe pathway, present in humans, in obesity and other conditions, warranting further research to understand the mechanism.

“This study unveils new prospects,” commented Dr. Jonathan Long from Stanford.

“In the future, using BHB-Phe to promote weight loss without carbohydrate restrictions may be feasible.”

Featured in this week’s cell journal.

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Maria Dolores Moya-Garzon others. The β-hydroxybutyrate shunt pathway produces anti-obesity ketone metabolites. cell published online on November 12, 2024. doi: 10.1016/j.cell.2024.10.032

Source: www.sci.news

Three-Carbon Compounds Found in Titan’s Atmosphere

Tricarbon molecule (C3) is probably produced in Titan’s upper atmosphere by the reaction of abundant acetylene with atomic carbon.



This view of Titan is one of the last images NASA’s Cassini spacecraft transmitted to Earth before entering the giant planet’s atmosphere. Image credit: NASA / JPL-Caltech / Space Science Institute.

Of the solar system’s more than 150 known moons, Saturn’s largest moon Titan is the only one with a substantial atmosphere.

And of all the places in the solar system, Titan is the only place other than Earth that is known to have liquid in the form of rivers, lakes, and oceans on its surface.

Titan is larger than Mercury and is the second largest moon in the solar system. Jupiter’s moon Ganymede is only slightly larger (about 2%).

Titan’s atmosphere is composed primarily of nitrogen, like Earth’s, but its surface pressure is 50% higher than Earth’s.

Titan has clouds of liquid hydrocarbons such as methane and ethane, rain, rivers, lakes, and oceans.

“Home to a thick and chemically diverse atmosphere, Titan stands out among the icy moons of the giant planets as one of the most thoroughly studied objects in the solar system,” said Lisboa Observatory and University of Astronomy. said Dr. Rafael Silva. of Lisbon.

“Titan’s atmosphere acts like a planet-sized chemical reactor, producing many complex carbon-based molecules.”

“Of all the atmospheres we know of in the solar system, it is most similar to the atmosphere thought to exist on early Earth.”

“Methane, which is a gas on Earth, provides information about geological and potentially biological processes.”

“This molecule cannot survive for long in the atmospheres of Earth or Titan because it is quickly and irreversibly destroyed by solar radiation.”

“Therefore, methane must be replenished on Titan by geological processes such as underground gas emissions.”

In the study, Dr. Silva and his colleagues UVES High Resolution Visible and Ultraviolet Spectrometer ESO’s Very Large Telescope.

They were able to identify 97 absorption lines for methane and one absorption line for the three-carbon molecule.

“Even in high-resolution spectra, the methane absorption lines are not strong enough for the amount of gas that can exist in a laboratory on Earth,” Dr. Silva said.

“But Titan has an entire atmosphere, and the path that light travels through the atmosphere can span hundreds of kilometers.”

“This allows various bands and lines that have weak signals in labs on Earth to be very obvious on Titan.”

“In our solar system, three-carbon molecules, which appear as bluish luminescence, were previously known only in the material surrounding the cores of comets.”

“The absorption lines in Titan that we have associated with tricarbons, although highly specific for this type of molecule, are small in number and low in intensity, so new observations will be needed in the future to confirm this detection.” will be done.”

“The more we learn about the different molecules involved in the chemical complexity of Titan’s atmosphere, the better we understand the types of chemical evolution that may have enabled or are associated with the origin of life on Earth.” You will be able to do it.”

“Some of the organic matter that contributed to the origin of life on Earth is thought to have been produced in the atmosphere by processes relatively similar to those observed on Titan.”

a paper The survey results were published in a magazine planetary space science.

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Rafael Lianzo Silva other. 2024. Study of Titan’s very high-resolution visible spectrum: Line characterization in visible CH.Four Search for band and C3. planetary space science 240: 105836; doi: 10.1016/j.pss.2023.105836

Source: www.sci.news

Webb discovers complex organic compounds in interstellar ice approaching dual protostars

astronomer using Mid-infrared measuring instrument The NASA/ESA/CSA James Webb Space Telescope's (MIRI) detected molecules ranging from relatively simple ones like methane to complex compounds like ethanol (alcohol) and acetic acid. interstellar ice One low-mass protostar and one high-mass protostar: toward NGC 1333 IRAS 2A and IRAS 23385+6053, respectively.



This image taken by Webb's MIRI instrument shows the region near the IRAS 23385+6053 protostar. Image credit: NASA/ESA/CSA/WRM Rocha, LEI.

Complex organic molecules (COM) are molecules with six or more atoms, including at least one carbon atom.

These materials are the raw material for future exoplanetary systems and are therefore of essential importance in understanding the chemical complexity developed in star-forming regions.

If this material becomes available in a primitive planetary system, it could facilitate the planet's habitability.

In a new study, astronomers Will Rocha, Harold Linnaerts and colleagues at Leiden University used Webb's mid-infrared instrument to determine the extent of COM ice in two protostars, NGC 1333 IRAS 2A and IRAS 23385+6053. We investigated the characteristics.

They were able to identify a variety of COMs, including ethanol (alcohol) and perhaps acetic acid (a component of vinegar).

“Our discovery contributes to one of the long-standing questions in astrochemistry,” Dr. Rocha said.

“What is the origin of COM in the Universe?” Are they created in the gas phase or in ice? Detection of COM in ice is based on the solid phase at the surface of cold dust particles It suggests that chemical reactions can build complex types of molecules. ”

“Some COMs, including those detected in the solid phase in our study, were previously detected in the warm gas phase, so they are now thought to originate from ice sublimation.”

“Sublimation is the change from a solid directly to a gas without becoming a liquid.”

“Therefore, we have hope that detecting COM in ice will improve our understanding of the origins of other, larger molecules in the universe.”



This figure shows the spectrum of the NGC 1333 IRAS 2A protostar. Image credit: NASA/ESA/CSA/Leah Hustak, STScI.

The researchers also detected simpler molecules such as formic acid, methane, formaldehyde, and sulfur dioxide.

“Sulfur-containing compounds, such as sulfur dioxide, played an important role in promoting metabolic reactions on early Earth,” the researchers said.

“Of particular interest is that one of the investigated origins, NGC 1333 IRAS 2A, is characterized as a low-mass protostar.”

“NGC 1333 IRAS 2A may resemble the early stages of our solar system.”

“Therefore, the chemicals identified around this protostar may have been present during the earliest stages of the development of the solar system and were later delivered to the proto-Earth.”

“All of these molecules could become part of comets, asteroids, and ultimately new planetary systems as icy material is transported inside planet-forming disks as protostar systems evolve.” '' said Dr. Ewain van Dyschoek, an astronomer at Leiden University.

“We look forward to using more web data in the coming years to follow this astrochemical trajectory step by step.”

of the team paper It was published in the magazine astronomy and astrophysics.

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WRM Rocha other. 2024. JWST Young Protostar Observation (JOYS+): Detection of icy complex organic molecules and ions. I.CH.FourSo2,HCOO,OCN,H2Colorado, Cooh, Switzerland3CH2Oh, CH3Cho, channel3Ocho and CH3Coo. A&A 683, A124; doi: 10.1051/0004-6361/202348427

Source: www.sci.news

Matabele ants discovered to use antibacterial compounds for treating infected wounds

Infected wounds pose a significant mortality risk to animals. Injuries are common in Matabeleari (Megaponera analis), raiding warlike prey. New research shows that these predatory ants can tell when a wound has become infected and treat it accordingly. Workers apply various antimicrobial compounds and proteins secreted from the retropleura to infected wounds, reducing mortality rates in infected individuals by 90%.

Matabeleari (Megaponera analis) He cares for the wound of a fellow ant whose leg was bitten off during a fight with termites. Image credit: Erik Frank / University of Würzburg.

Infectious diseases are a major mortality risk for animals, and animals that live in groups are particularly at risk of contracting life-threatening contagious pathogens.

This has led to a series of pathogen-induced changes in social interactions, including social distancing, disease signaling, and medical care.

Injured people are an easy entry point for life-threatening infections because their primary barrier to infection, the epidermis, or epidermis, is damaged.

Recently, some mammals have been shown to lick wounds to apply antiseptic saliva. However, the effectiveness of these actions remains largely unknown and occurs regardless of wound status.

In social insects, interactions to combat pathogens range from preventive measures such as nest disinfection and conspecific grooming, to dying individuals leaving the nest and dying in isolation, to destructive disinfection of infected mates. It's wide-ranging.

However, whether and how social insect colonies care for injured individuals exposed to pathogens is still poorly understood.

Predatory Matabele ant workers have been known to treat injuries to their nestmates, a common occurrence since the ants only feed on belligerent termites. As many as 22% of collectors engaged in termite raids lose one or two of their legs.

Injured workers are carried to the nest, and for the first three hours after injury, other workers treat the wound by licking and grooming the wound.

If the wounds of injured workers are not treated by nestmates, 90% of the injured workers die within 24 hours after injury, but the mechanisms of these treatments are unknown.

“The aim of our study was to identify the causes of death in injured individuals and the potential mechanisms involved in the detection and treatment of injuries,” said first author Eric, a researcher at the University of Lausanne and the University of Würzburg.・Dr. Frank said. , and his colleagues.

they discovered gram-negative bacteria Pseudomonas aeruginosa It caused a fatal infection in injured Matabele ant workers.

They showed that wound infections were associated with specific changes in the epidermal hydrocarbon profile, allowing nestmates to diagnose the infected status of the injured and apply appropriate antimicrobial treatment. .

They also identified 112 chemical compounds and 41 proteins in secretions from the ants' posterior thymus, half of which were found to have antibacterial or wound-healing properties.

“Chemical analysis showed that the hydrocarbon profile of the ant's epidermis changes as a result of wound infection,” Dr. Frank said.

“It is precisely this change that allows the ants to recognize and diagnose the infection status of injured nestmates.”

“For treatment, they apply antibacterial compounds and proteins to the infected wound. They ingest these antibiotics through the retropleura, which is located on the side of the thorax.”

“The secretion contains 112 components, half of which have antibacterial and wound healing effects.”

“And this treatment is highly effective, reducing the mortality rate of infected people by 90%.”

“Aside from humans, I don't know of any other creature capable of such sophisticated wound healing.”

“These findings have medical implications because the main pathogens in ant wounds are Pseudomonas aeruginosait is also a major cause of human infections, and some strains are resistant to antibiotics,” said the study's senior author, Dr. Laurent Keller from the University of Lausanne.

of result appear in the diary nature communications.

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ET Frank other. 2023. Targeted treatment of injured nestmates with antimicrobial compounds in an ant community. Nat Commune 14, 8446; doi: 10.1038/s41467-023-43885-w

Source: www.sci.news