Tag Archives: Hair

Red Tattoo Ink Linked to Hair Loss and Sweating Issues: A Cautionary Tale

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Inflamed Areas of a Man’s Tattoo

University Centre for General Dermatology and Oncodermatology, Wrocław Medical University

A Polish man experienced a severe allergic reaction to the red ink used in his tattoo, resulting in hair loss, cessation of sweat production, and the development of vitiligo. This alarming case highlights potential adverse effects of certain modern tattoo inks on the immune system.

Tattooing is a time-honored practice that traditionally utilized black soot-based inks and manual techniques. Today, electric tattoo machines are employed to rapidly apply colorful synthetic inks across larger skin areas.

Many dyes found in colored tattoo inks were originally formulated for use in printer inks and automotive paints, not for human application. Reports of allergic reactions to colorful tattoo inks have surged in recent years, particularly among individuals with existing immune issues, such as eczema, asthma, and celiac disease. According to research, around 6% of people report allergic reactions that persist for more than four months, particularly with red ink.

The Polish man’s symptoms began four months post-tattoo application on his forearm. Initially, itched intensely, followed by the emergence of a widespread red rash. Over time, he developed hair loss, yellowing nails, swollen lymph nodes, and an inability to sweat. After two years, he also noticed large patches of vitiligo.

Despite consultations with several specialists, including dermatologists and allergists, the underlying issue remained undiagnosed. It wasn’t until the red ink decorations of his tattoo became visibly inflamed that suspicion arose. A biopsy of a swollen lymph node revealed traces of red ink had migrated from the tattoo site.

Due to limited treatment options, the man underwent eight surgeries to eliminate the problematic red ink and apply skin grafts. Post-treatment, while his hair has regrown and vitiligo has stabilized, he still suffers from permanent dysfunction of his sweat glands, presenting a risk of heat exhaustion and necessitating his resignation from military service, as he must frequently spray himself with water.

Despite attempts, dermatologists at Wrocław Medical University could not obtain a sample of the red ink for analysis. However, past studies have identified synthetic organic dyes, particularly azo dyes, as agents responsible for allergic reactions in red tattoos.

The potential health risks associated with tattoo ink are linked to its chronic activation of the immune system. Most tattoo ink remains on the skin, but some can migrate to lymph nodes. Here, immune cells known as macrophages attempt to eliminate the ink but often fail due to its size. This failure leads to a cycle of immune activation, as macrophages transfer the ink to others, perpetuating the immune response. Dr. Sine Clemmensen of the University of Southern Denmark elaborates on this issue.

The Polish man also had Hashimoto’s disease, an autoimmune condition that may have heightened his sensitivity, resulting in the immune system mistakenly attacking his skin.

Emerging research suggests that even individuals without pre-existing immune conditions might face long-term risks related to tattoos. Clemmensen’s findings indicate that having any tattoo color could triple the risk of developing lymphoma, a cancer affecting the lymphatic system.

In January 2022, following another case similar to that of the Polish man, the European Union initiated measures to enhance tattoo safety by restricting chemicals commonly found in tattoo inks with azo dyes. However, legislation in other regions is still pending.

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Source: www.newscientist.com

Study Indicates Gray Hair May Result from the Body’s Shutdown of Cancer-Prone Cells.

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Gray hair might represent the marks left by our bodies in the battle against cancer, according to a new study.

The recently released Natural Cell Biology explores how the cells that provide pigment in our hair and skin “self-destruct” upon damage, as part of the body’s protective measures against cancer.

Researchers have found that when these pigment-producing cells experience certain types of damage, they cease to function on their own instead of continuing to divide.

This selection process helps to prevent the spread of faulty cells that can cause harmful mutations, but it ultimately leads to a decline in pigment-producing cells over time, resulting in gray hair.

While scientists have been examining methods to prevent the self-destruction of pigment cells to combat gray hair, recent findings indicate that gray hair may indicate a significant anti-cancer defensive mechanism.

Damaged DNA can lead to mutations and cause cancer – Credit: Getty

“[This study] indicates that gray hair and melanoma are not unrelated occurrences but are framed as varied outcomes of stem cell stress responses,” stated Professor Emi Nishimura of the University of Tokyo, who spearheaded the research.

The Tokyo team made this revelation while examining mouse melanocyte stem cells, which are responsible for producing hair pigment. They found that these melanocyte cells only sacrificed themselves when their DNA faced a “double-strand break,” or a precise cut on both sides of the DNA helix.

However, when the cells encountered different stressors, like ultraviolet light or carcinogens, they did not undergo self-destruction. Instead, they survived and continued to divide, allowing mutations to accumulate and potentially paving the way for cancer.

These two distinct responses—cells opting for self-sacrifice in some situations but persisting in others—may help clarify why gray hair and skin cancer become increasingly prevalent as we age.

Researchers suggest that gaining a deeper understanding and ultimately controlling this response could lead to innovative methods for eliminating high-risk cells before they turn cancerous.

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Source: www.sciencefocus.com

People with Red Hair May Experience Slower Healing for Cuts and Scrapes.

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Our hair color seems to influence wound healing in unexpected ways

Stock Enjoy/Shutterstock

Red-haired individuals might experience slower wound healing compared to those with blonde, brunette, or dark hair. Research conducted on mice indicated that genetic differences related to hair color may affect the speed at which wounds heal, insights that could lead to improved treatment strategies for various hair colors.

The genes responsible for our hair color play a significant role. The gene MC1R is critical as it produces a protein determining the balance of black-brown and red-yellow pigments within hair follicles.

Individuals with brown or black hair typically have an MC1R variant encoding the active version of this protein. In contrast, nearly all redheads possess a less active or entirely inactive variant due to MC1R mutations. The genetics of hair pigmentation is complex for blondes, too, as they can display either active or inactive protein forms.

This protein is also present in the skin and has an anti-inflammatory effect. This led Jenna Cash from the University of Edinburgh to explore its influence on wound healing. The healing process requires an initial inflammatory response to clear out pathogens and dead cells from the injury site; however, if this response is too intense or prolonged, it can hinder proper healing.

To examine this, she and her team surgically created 4-millimeter wounds on the backs of black and red-haired mice, the latter having completely inactive MC1R protein.

After a week, red-haired mice exhibited an average scar contraction of 73%, while dark-haired mice showed a 93% contraction.

With these results in mind, the researchers hypothesized that an experimental topical agent, which enhances the activity of the active protein form (without impacting the inactive form), could aid in healing chronic wounds. This is particularly relevant for diabetics, in whom persistent high blood sugar can lead to excessive inflammation and delayed healing.

To test this hypothesis, the researchers inflicted wounds on black-haired mice and treated them with medication and bandages, while other black-haired mice with similar wounds received saline and bandages instead.

After one week, wounds of the treated mice had closed by an average of 63%, significantly larger than those of control group mice. “Patients would likely be pleased if their scars were visibly smaller, especially in a short timeframe,” noted Cash. Further analyses revealed the drug’s mechanism: it reduces the number of inflammatory immune cells.

This approach offers potential for treating humans, including redheads, as healing processes show remarkable similarities between mice and humans, most of whom have the MC1R protein functioning to some extent, Cash notes. However, patients with completely inactive forms may not see benefits.

Drugs targeting this protein are currently used for conditions like erythropoietic protoporphyria, making the researchers optimistic about the safety profile of this approach, according to Cash. Nonetheless, further studies are necessary to confirm this, as highlighted by Cas Bogey from Case Western Reserve University. Plans for human trials will commence shortly.

Future studies should also investigate the drug’s safety and efficacy on infected wounds, as Bogey pointed out. “The medication might interfere with the infection response or cause unintended side effects,” she cautioned.

This news may not be received well by some redheads. Prior studies indicate that red-haired individuals might also experience heightened sensitivity to pain. However, Cash reassures, “There’s no cause for alarm. We currently lack human data. Even if individuals with red hair heal somewhat more slowly, the difference may be negligible and hardly noticeable.”

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Source: www.newscientist.com

The serum stimulates hair growth by imitating skin irritation effects.

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Eczema-like stimulation promoted hair regrowth in shaved mice over 20 days (bottom row). Meanwhile, hair growth was notably less in shaved mice lacking this stimulation (top row).

Tai et al. 2025

Skin inflammation can encourage hair growth in mice by activating fat cells. The serum derived from this process may also benefit humans without causing discomfort.

While hair loss is often addressed with medications or steroid injections, more effective solutions are being researched, including stem cell therapies and drugs that reactivate dormant hair follicles.

Songjian Lin, among researchers at National Taiwan University, became intrigued by how adipose tissue influences hair growth during experiments with mice. “Unexpectedly, we found changes in the size of fat cells following skin inflammation. [Fat cells] shrink quickly before hair starts to grow back. We proposed that fat cells could release fatty acids via lipolysis to spur hair regeneration,” Lin explains.

To explore this further, they repeated the study and examined the relevant cells more closely. They initially applied an irritant to a shaved section of the mouse’s back to simulate eczema. By day ten, they noted that the mice’s hair follicles were actively growing, resulting in visible hair growth in those regions. This effect was absent in other shaved areas without eczema, as well as in control mice.

The research team observed that this phenomenon appears to occur because immune cells called macrophages migrate to the fat layer beneath the mouse’s skin, signaling fat cells to release fatty acids. These fatty acids are then utilized by hair follicle stem cells, promoting increased mitochondrial production, which supplies energy and fosters hair growth. This aligns with past studies indicating that plucking hair can trigger immune responses in nearby hair follicles, stimulating their growth.

Though eczema isn’t typically linked to hair growth in humans, other forms of skin inflammation may play a role, such as those associated with casts for broken bones, which are connected to excess hair growth.

Next, Lin and his team sought to determine whether fatty acids alone could induce hair growth without prior irritation. They formulated a serum containing various fatty acids dissolved in alcohol. This serum was applied to non-irritated shaved mice, and the results were compared to untreated areas and control mice. “We discovered that only monounsaturated fatty acids, like oleic acid and palmitoleic acid—prevalent in adipose tissue—successfully induced hair regrowth when applied topically,” Lin notes.

The researchers, who have since patented the serum, also observed encouraging outcomes when tested on human hair follicles in the lab and now intend to evaluate different dosages on human scalps.

Lin does not anticipate any serious side effects from the treatment. “Oleic acid and palmitoleic acid are naturally occurring fatty acids. They are present in high quantities in our fat tissue and various vegetable oils, making them safe for use,” he states. “I applied a solution of these fatty acids mixed with alcohol to my thighs for three weeks and noticed it stimulated hair growth.”

However, he cautions that the treatment hasn’t yet undergone testing on human skin, and animal models may differ significantly, especially concerning hair follicle biology. Christos Tziotsios from King’s College London also points out that similar serums are under development, including one utilizing plant extracts that promote hair growth in a matter of weeks.

Nonetheless, Tziotsios affirms that the latest findings enhance our comprehension of hair growth and loss. “We were aware of fat cells’ involvement in hair follicle formation, but this is the first instance we’ve witnessed them playing a role in hair regeneration,” he remarks. It could also clarify why certain individuals experience hair growth post-microneedling treatments, which involve rolling fine needles across the scalp to create micro-injuries that elicit an immune response.

Source: www.newscientist.com

Plant Extract Serum Boosts Hair Growth in Just Weeks

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Hair growth significantly enhanced after 56 days of serum use

Tsong-Min Chang et al. 2025

A serum aimed at reversing hair loss has shown promising outcomes within a two-month period. This topical treatment, formulated with plant extracts and proteins that stimulate cellular activity, demonstrated notable enhancements in hair density compared to a placebo.

Hair loss affects approximately: 50% of men and 40% of women by the time they reach 50. Various treatments, such as finasteride and minoxidil, also known as Rogaine, may be effective; however, their success can vary based on genetics and the degree of hair loss.

Researchers are exploring innovative techniques for hair regeneration, including stem cell applications. Investigations into fibroblast manipulation, a cell type crucial for connective tissue formation, and a drug aimed at revitalizing dormant hair follicles are underway.

In a unique approach, researchers from Schweitzer Biotech in Taiwan have developed a serum enriched with caffeine, commonly found in health products, alongside two proteins known to enhance cellular growth: Insulin-like growth factor-1 (IGF-1) and Fibroblast growth factor-7 (FGF-7), both displaying potential for hair follicle regeneration. Additionally, extracts from Centella asiatica, a tropical herb widely used in skincare, appear to support hair follicle health.

To evaluate efficacy, an international research team enlisted 60 adults aged 18 to 60 without severe hair loss. Participants were divided into five groups; the first group received a placebo serum devoid of active ingredients, while the second group was provided with a basic preparation of 0.1% caffeine and vitamin B5, known for its moisturizing properties. The remaining groups used this base formulation, with the third group incorporating IGF-1 and FGF-7, the fourth group including IGF-1 and FGF-7 with C. asiatica, and the fifth group receiving all components.

All participants were instructed to apply 1 milliliter of serum to their entire scalp nightly for 56 days. Improvements were observed in all groups across various measured outcomes, including hair density, thickness, and reduced hair loss. The most significant increase in hair density was found in Group 5, which saw nearly a 25% improvement—almost double that of the placebo group.

Researchers propose that C. asiatica extracts may enhance hair root strength and boost blood circulation around hair follicles. “This plant has been recognized for its anti-aging, reparative, and anti-inflammatory properties,” explains Christos Tziotsios from King’s College London. “It could be somewhat of a miracle plant. There’s stronger evidence for some of the other components in this study. For instance, IGF-1 and FGF-7 are both known to influence hair cycle dynamics.”

Participants in Group 5 demonstrated improved hair growth

Tsong-Min Chang et al. (2025)

Both Tziotsios and the research team emphasize that while the study’s scale is noteworthy, extended trials are essential before a treatment utilizing this formulation can be deemed available. “This doesn’t negate its potential interest, but it’s clear that further investigation is required,” says Tziotsios. “The more we comprehend the molecular mechanisms linked to hair loss and hair biology, the closer we will be to achieving a definitive treatment.”

Source: www.newscientist.com

Carved Head Suggests Hair Trends of Ancient Hunter-Gatherers

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SEI 265224007

Engraved face from the French Amien Lannancourt 1 site

Stephen Lancelot/In-Rap

Miniature sculptures estimated to be 27,000 years old from northern France may offer insights into how ancient hunter-gatherers styled their hair.

The figurine was unearthed in 2021 from a site known as Amien Lannancoeur 1, located roughly 140 kilometers north of Paris, and has recently been analyzed by researchers.

Notably, the long hair appears to be braided in a grid pattern, possibly representing hair nets or distinct hairstyles. This contrasts with figures found in Central and Eastern Europe, where hairdos are typically short and cover the majority of the head, according to Olivier Touse from the University of Liège, Belgium, who did not participate in the study.

The statuette’s distinctive hairstyles may indicate the period and local fashion trends. “This might represent a cultural uniqueness that would not have been highlighted without these scarce human representations,” states team member Clement Paris from the National Institute of Preventive Archaeology in France.

Radiocarbon dating of the rock layers at Amiens-Renancourt 1 indicates that the sculpted figure dates back to approximately 27,000 years ago and belongs to the Greybettian period, which spanned from 33,000 to 26,000 years ago across Europe. Following this era, the hunter-gatherer population vacated Northwest Europe for nearly 10,000 years due to the severe cold and arid conditions of the last Ice Age’s peak, notes Touzé.

“The intricate decoration and well-defined hairstyles underline the attention devoted to the craftsmanship of this statue,” remarks Gregory Abrams at the University of Ghent, Belgium, who was not involved in the study.

Other excavations at the site have uncovered several small fragments and over a dozen additional figurines, including Venus figurines that depict women. “This site has historical significance regarding sculptural production,” states Touse.

Yet, questions linger about what these figurines reveal about their creators. “Prehistoric thoughts and myths leave minimal evidence,” comments Paris. “And even when these statues provide insight, their significance remains obscure.”

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Source: www.newscientist.com

Discover “Monster” Tumors That Can Develop Hair, Teeth, and Organs

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This concept may surprise you, but certain tumors can indeed develop parts of your body, or at least fragments of them.

These peculiar layers, known as teratomas, originate from germ cells that possess the extraordinary capability to transform into any type of tissue.

Germ cells typically evolve into sperm or eggs; however, when their development is disrupted, they can create a disorganized mass of tissue.

The term “Teratoma” is derived from the Greek word Teras, which means “monster,” aptly reflecting its nature.

These tumors feature an astonishing array of components, ranging from hair and teeth to muscle tissues and even organ-like structures such as the thyroid and eyes.

While fully functional organs are exceedingly rare, the intricate nature of these tumors is undeniable.

Teratomas are most frequently observed in the ovaries and testes, but they can also appear in the midline of the body, such as the mediastinum (the chest area that houses the heart) and the base of the spine.

The majority of teratomas are benign and can be easily excised, though a small percentage—particularly those in men—can become malignant and necessitate urgent treatment. Surgery is generally the primary method for addressing these tumors, and the prognosis is typically favorable.

It can grow teeth, muscles, thyroid, eyes, and other tissues from the teratoma – Image credit: Science Photo Library

In addition to their medical implications, teratomas have offered significant insights into the science of cellular development.

They can include tissues derived from all three layers of germ cells, making them an intriguing model for studying how cells differentiate and organize.

So, can a tumor grow organs? In a way, yes. However, these structures are often nonfunctional and poorly organized.

Teratoma serves as a striking and unsettling example of the bizarre and unpredictable aspects of human biology.

This article addresses the question posed by Anisa Manning and Steve Nage: “Can tumors grow their own organs?”

If you have questions, please email us at Question @sciencefocus.com or message us on Facebook, Twitter, or Instagram (please include your name and location).

Explore our ultimate Fun Fact and more captivating science pages.

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Source: www.sciencefocus.com

Balge’s End: The Secret to Hair Regeneration Unveiled

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For some individuals, baldness may just be in their genetic destiny, as evidenced by the photo of Dwayne Johnson sporting curly hair. However, for millions dealing with hair loss due to genetics, aging, hormones, or medical conditions, recent discoveries may bring them closer to maintaining a full and lush scalp.

This progress is attributed to a new study published in the journal Natural Communication.

Researchers conducting the study used mice as subjects to delve into the mechanisms of hair follicle regeneration and the factors contributing to their demise.

In our bodies, all hair and the follicles under the skin go through cycles of growth, death, and rest. Key players in regulating the growth of new hair are hair follicular stem cells.

Hair follicles are naturally intended to die as part of the growth cycle. When they fail to regenerate, hair loss occurs. – Credit: Christopher Robbins via Getty

The study identified a protein called MCL-1 and conducted experiments to determine its function by turning it off and observing the effects on the mice.

“The researchers utilized advanced molecular biology tools to essentially remove proteins and examine the outcomes,” explained tissue engineering expert Professor Sheila McNeill, who was not part of the research team, as reported by BBC Science Focus.

By disabling MCL-1 in some mice from birth and in others after they had already lost some hair, scientists found that without MCL-1, new hair could not grow as hair follicle stem cells seemed to die off. This led to gradual hair loss in young mice and stalled growth in adult mice.

The findings suggested that MCL-1 plays a crucial role in protecting hair follicle stem cells, enabling new hair growth when old follicles die. Without this protein, hair follicles fail to regenerate.

McNeill emphasized that this study lays a solid foundation for further research, exploring whether individuals experiencing hair loss exhibit signs of MCL-1 damage and investigating ways to safeguard the protein to prevent hair loss.

However, cell biologist Professor Dorothy Bennett from St. George’s, University of London, cautioned that translating this research into a hair loss treatment presents significant challenges.

“MCL-1 is an intracellular protein, and intact proteins cannot easily penetrate cell membranes to reach their targets. Therefore, delivering MCL-1 through topical solutions or pills is unlikely to be effective,” Bennett explained.

Nevertheless, the study did identify a potential workaround through the activation of another protein, the epidermal growth factor receptor, which can boost MCL-1 levels. While this offers a promising alternative, Bennett stressed that developing such treatments presents numerous hurdles.

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About our experts:

Sheila McNeill: Professor Emeritus of Biomaterials and Tissue Engineering at the University of Sheffield, UK. McNeil specializes in tissue engineering for soft tissues and has a strong focus on research translation, with a vast publication record.

Dorothy Bennett: Research Professor in Cell Biology at St. George’s, University of London, UK. Bennett’s research interests include cell senescence, genetics of melanoma, and other pigmented skin conditions.

Source: www.sciencefocus.com

My parents found popcorn in my hair and it turned into a magical meme from Minecraft movie games

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tDuring his week I took my son Zack with me to watch a new Minecraft movie. This is not a surprising statement in the world of highly video game brands of cinemas in the 21st century. At least, it’s not yet.

As we’ve seen in many bewildered news reports over the past few days, Minecraft films quickly created a community of extremely enthusiastic and enthusiastic fans. Spurred by Tiktok Meme posts, a huge portion of the film’s audience screams and sings to the song, citing important lines when they happen. At one key moment when the game’s rare character, the zombie chicken jockey, is introduced, they absolutely go crazy, throwing drinks and throwing popcorn. Escorted from a police screening.

Our small independent cinema in Fromm had a little more calm reaction, but there was still a line of teenagers who saw all of Tiktok posts screaming about them all. It was loud enough for cinemas to post on Facebook about antisocial behaviour and illegality of recordings in the film.

There is much to unfold here about the exclusive nature of internet culture, cinema etiquette, and the online community’s transition to physical space. Most of the audience’s reactions were fine. It’s a deliberately a Daft film made for fans, and it’s thrilling to celebrate fandom with like-minded peers in a crowded space. The film itself always rewards people who are immersed in fiction. We also enjoy finding a lot of Easter eggs (“Oh, that’s hero blin!”) and small cameos from Minecraft Youtubers and game developers. There are also some really funny moments of slapstick and sarcasm, depending on the committed performances from Jack Black and Jason Momoa.

Flying as high as the popcorn in the movie… a Minnecraft movie. Photo: Warner Bros./AP

But for Zack, who is 19 and with autism, and for many of the little kids in the auditorium, the atmosphere can be confused and a bit intimidating. Although screenings for Marvel films such as Avengers: Endgame and Spider-Man: No Way Home were compared to wild responses, mostly spurred by events at FILM Infilm. We all understood why Captain America successfully caught Thor’s hammer and people cheered on.

With Minecraft films, the prompts for audience responses are primarily from memes and are a branch of inexplicable internet comedy in its nature. The joke is that you can see jokes from other people who get jokes. Out of context, memes are private jokes where you are. Perhaps the closest analogy is the culture around rocky horror picture shows That legendary fan screening It features a water pistol and drug outfit at Fleapit Cinemas. However, these events were opt-in. Everyone knew what they were getting. I don’t know if the same can be said for all parents who leave my screening picking my screening from my hair.

But we really enjoyed watching the movie. When Zack was young and had a hard time communicating, Minnecraft was a precious outlet for him, allowing him to be creative and make friends. He still plays to this day. It was his comfortable blanket and it changed our lives – especially because I ended up writing a novel, a boy made with blocks, inspired by our experiences in the game. It was an emotional experience to hear that refined piano music in the film, share those jokes, and see what had a huge positive effect on my family portrayed on a huge screen among other fans.

Of course, teenagers are Assumption To be confused and intimidating – that’s their job. You can’t wander around by handing over an uneasy generation, saying, “They’re pranks so let’s ban them from the cinemas.” Also, during these challenging times for the film industry, filmmakers need to find ways to engage with teenage audiences who are out, whether it is due to the cost, social anxiety, and the all-inclusive nature of digital culture. Minecraft movies are the most perfect unicorns in the entertainment business. A multi-million dollar blockbuster that has reached the most unreachable generation of modern history. Many studios get busy solving how to film this meme-soaked magic on a bottle.

Perhaps the film owners will be wise and organize their dedicated autism-friendly screening, or on the other side of the scale, embrace chaos and do a special fan night. They need to prepare to pay a little extra to the cleaning staff.

What to do

Like an old war comic… Commandos: Origin. Photo: Kalypso Media

Hundreds of years ago (well, 1998), my favorite example of the busy genre of real-time strategy at the time was Commandos. Commandos: Origin It is a rethink of the series, modernizing the intricately detailed isometric landscape of the original, focusing on stealth and sabotage. It’s like you’re in your own interactive version of an old war cartoon Warrior and Combat actionand I am ready to lose repeatedly trying to take the sniper to the Guard Tower without being discovered by the Nazis on the patrol.

Available at: PC, PS5, Xbox
Estimated playtime: Over 20 hours

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What to read

The Nintendo Switch 2 still wraps some specs. Photo: Richard Drew/AP

  • I have a polygon Some interesting follow-ons Since recently Nintendo Switch 2 Announcement: The console’s highly heralded group chat feature is not free. Instead, owners will have to pay a monthly fee to talk to their peers while playing.

  • Elsewhere, it was produced by the Digital Foundry team at Eurogamer Typically a good deep dive Inside Console technical specificationswe still don’t know much.

  • UsingGame development AI It continues to be debated This aftermath feature Talking to a game maker who has to deal with artificial intelligence is eye-opening and important.

What to click

Question block

They haven’t lost the plot… Dragon Ball Fighters. Photo: Namco Bandai

This week’s question comes from Stephen Man Blueski, asked:

“Fighting games tend to have some of the deepest stories. But there’s a stigma that fighting games are just a button-click competitive. What can developers and players do to break this stigma?”

I think this comes from the disconnect between the action in the fighting game and the content of the story. Usually, all stories occur with cutscenes and pre-match taunts, so players can feel separated from lore. Some fighting game designers have begun to draw more stories interactively to express the story using specific locations, costumes and movements. I think Injustice and Blazblue Do a good job with this during Namco’s anime-based fighter jets Dragon Ball and Naruto It really packs the ongoing plot into the fight. Fighting game developers may be able to consider splitting the match to enter story sequences, so players will invest more money in the story and understand the stakes. As for players, I have always found the fighting gaming community to be extremely welcome. That’s all they really need to do.

If you have a question blocking question or anything else to say about the newsletter, please click reply or email us at butingbuttons@theguardian.com.

Source: www.theguardian.com

Research suggests we have found a quick solution to eliminate wrinkles and grey hair forever.

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A recent study has discovered several potential anti-aging treatments that could help prevent wrinkles and gray hair development.

Published in the journal Endocrine review, this research suggests that certain naturally occurring hormones might be able to slow down the aging process in the body.

“Our study sheds light on key hormones that play a role in regulating pathways associated with skin aging, including connective tissue degradation (which leads to wrinkles), stem cell survival, and pigment loss (which causes graying of hair),” explained Professor Markus Böhm from the University of Munster, Germany.

“Some of these hormones have shown anti-aging properties and could potentially be used as treatments to prevent skin aging in the future.”

The primary focus of this research was to examine the connection between hormones and aging, with a particular emphasis on hormones like estrogen, growth hormone, and melatonin, all of which can impact skin aging.

One hormone that stood out in the study was melatonin. While commonly known for its role in regulating sleep, melatonin was found to also play a role in maintaining youthful skin. Its powerful antioxidant effects help protect skin cells and slow the aging process.

Other hormones, such as melanocyte-stimulating hormone and oxytocin, were also identified as potential contributors to maintaining youthful skin and hair and protecting against UV damage.

The skin, being the body’s largest organ, is prone to damage from environmental factors, especially UV rays from the sun.

“The skin not only responds to various hormones that impact skin aging pathways, but it is also a significant site for hormone production, aside from the traditional endocrine glands like the pituitary gland,” added Böhm.

Researchers are hopeful that these findings will lead to the development of a new anti-aging therapy known as Senotherapeutics, which targets and eliminates senescent cells. By doing so, these drugs may help slow down or even reverse the signs of aging that result from the accumulation of these cells in the body over time.

“Further research on these hormones could pave the way for the development of new treatments to address and prevent skin aging,” concluded Böhm.

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Source: www.sciencefocus.com

The environmentally friendly black wood-scented hair conditioner

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The conditioner for the black hair on the left comes from the wooden powder on the right

Feng Shui King/Stockholm University

This sustainable wood-based hair conditioner may smell pure white and peat-like, but its creators suggest that the tests may work similarly to commercial products. They claim that it could become a future for hair care.

“We use the power of nature.” Ievgen Pylypchuk At Stockholm University in Sweden. “We combine high-level science with old traditions… [to] Get something really cool: simple, convenient, and very effective. ”

Pylypchuk and his colleagues used lignin, a polymer, a central component of wood and bark, as a starting point for bio-based conditioners. When extracted from wood, lignin naturally interacts with water It also functions as a surfactant, but is an important ingredient in surfactants. It also contains natural antioxidants that help preserve the conditioner, providing UV protection, says Pylypchuk. “In this context, lignin functions as a multifunctional platform,” he says. “It protects against UV rays and keeps you moisturized.”

The researchers combined lab-developed ligning gel with coconut oil and water to create the final product. Team Members Mika ShipponenStockholm University also claims it works much the same as commercial conditioners. When used with moist bleached human hair samples and then washed away, combing hair while 13% moisturizing reduces the “drag” and resists, compared to the commercial products tested. has decreased by 20%.

One potential drawback is that the current formula of conditioners is “pain black” and smells like “cooked wood” that resembles peat, Shipponen says. It does not prevent researchers from pondering its commercialization. They say they test hair, towels and pig skin formulas and wash them off without leaving any dirt. Even the smell is very comfortable, says Pylypchuk. “I personally liked it so much, and most of the people in our lab – maybe because they work with Lignin – they liked it.”

Pylypchuk and Sipponen There is a patent We hope that ligningel and conditioners will become consumer products, offering people a more sustainable alternative to current products that rely on ingredients derived from fossil fuels. They say the next step is to see if it causes irritation to the eyes and skin prior to the trials of living hair.

However, American cosmetics researchers Trefor Evans, Previously, he was at the Textile Research Institute in Princeton, New Jersey, where he questioned how well his products would work compared to his commercial rivals. “I've been doing these experiments for 30 years, and traditional conditioner products reduce the power of the comb by 80%, perhaps 90%,” he says. Shipponen believes that variations in hair testing methods and condition during analysis can explain whether his team was reduced by only 20% of commercial conditioners.

The appearance and unusual smell of wood-based conditioners may drive away consumers, Evans says. “Patent literature is absolutely packed with stuff. “And the reason is that you don't just need effectiveness. What you really need is aesthetics for consumers to buy it.” ”

So, will a black, lush, environmentally friendly conditioner be a hit with consumers? “It sounds a bit like a starter,” Evans says.

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Source: www.newscientist.com

Hair Tests for Autism Screening

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summary

  • Tests designed to identify biomarkers associated with autism have become available in most states.
  • The test is intended to help doctors rule out autism in children who are likely to do so.
  • The results are based on metabolic analysis that requires only the hair chain, but experts say more research is needed.

Tests designed to identify biomarkers associated with autism in infants and young children are open to the public in most states.

New Jersey startup Linusbio began testing on Thursday called Clearstrand-ASD. This test requires only one strand of hair.

This test is neither designed to diagnose autism spectrum disorder nor to be used alone. Instead, it aims to help doctors rule out autism in children, which is likely to be the case. This may be because the child has a sibling with autism or demonstrated behaviors related to the disorder.

Manish Arora, co-founder of Linusbio and its CEO, said Clearstrand-ASD is the only biochemical test available to detect autism spectrum disorder in children under 18 months of age. He hopes it will make the process of eliminating autism more efficiently and reduce the waiting time for those who need intervention or treatment the most.

“The focus is really on early intervention,” Alora said. “The sooner you intervene, the better your kids will.”

This test uses children’s hair to analyze the history of metabolism. Metabolic history tells the story of substances or toxins that have been exposed or processed over time, Arora previously told NBC News. His research has identified patterns of Metal exposure or metabolism dysregulation Some evidence suggests that it may be related to autism. Hair can provide a kind of timeline of what is happening in a child’s body, including patterns of metal exposure at certain stages of development.

“We can detect a clear rhythm of autism with about a centimeter of hair,” Arora previously told NBC News, and what the environment was like during a certain period of growth when a wooden ring was growing. We compared the dynamics and ways in which the story can be told.

The Food and Drug Administration has not approved the Clearstrand ASD test. However, as of Thursday, it is available to consumers in 44 states. If only I could pay $2,750. (I am not eligible for insurance coverage yet.) This test can be ordered directly from a primary care provider or Linusbio. This sets up the appointments of the independent physicians and telehealth that it offers, Arora said.

“You come to us, you get a prescription from an independent clinician. We’ll send you a kit. You’ll get results within about three weeks,” he said.

Diagnostic aid is still in the early stages of development, with limited data supporting its effectiveness. On Thursday, Linusbio shared several new first findings at the Metabolomics and Human Health Conference in Ventura, California. In a group of 490 children in California, who are at high risk for autism spectrum disorder, the test was able to eliminate it with an accuracy of around 92.5%, the company said. However, the results are not published in peer-reviewed journals.

2022 study on the company’s methodologyWe analyzed another Linusbio test published in the Journal of Clinical Medicine and found that it was still under development and that the methodology accurately predicts autism diagnosis (positive and negative) about 81% of the time .

The test is one of several promising ideas researchers are pursuing as a way to identify or exclude autism early in their children’s lives. Other scientists are considering eye tracking, blood tests and audio analysis as possible methods.

ClearStrand-ASD works by running the laser on the length of the hair being tested, turning the hair into a plasma that can be processed with machine learning algorithms. The results of the full analysis are expected within 3 weeks, after which the parents of the child participate in the follow-up telehealth appointment.

External experts said that while Linusbio’s hair strand test is promising, more research is needed.

“For me, this feels like it’s not the earliest, it’s on the early side of things. Stephen, a professor of pediatrics at the University of Missouri School of Medicine and Thompson Center for Autism and Neurodevelopment, Stephen, a professor of pediatrics at the University of Missouri School of Medicine and Thompson Center for Autism and Neurodevelopment. Schenkop said: “This seems like an approach that could become part of a set of ways children can be screened for concern, but it’s more. It’s at the stage where you need evidence of that.

Sheinkopf works closely with primary care physicians who are concerned about the possibility of autism by families with young children who are careful to monitor their development and screen for autism. It suggested that there was.

“Sometimes, I see new shiny tools. I want to skip what’s already available,” he said.

Sheinkopf also noted parents who have evidence of differences in child development You can seek federally mandated services without a formal diagnosis.

Seeking a diagnosis of autism in a child can take a long time. American Academy of Pediatrics Autism screening is recommended at 18 and 24 months. Neurological tests, language assessment, behavioral observation, and other methods are ultimately used to diagnose children.

By helping to rule out autism in some children, Arora has given priority to the attention of those most needy, and wait times for families seeking care and treatment. He said he hopes it can be shortened.

Rebeccaranda, executive director of the Center for Autism Services, Science and Innovation at Kennedy Krieger Institute, a Baltimore pediatric care center focused on developmental disorders, has a shortage of experts to help diagnose and treat autism. He said he is doing it. That’s why she hopes that the test will make the child’s flow to professionals more efficient.

“It can accelerate the speed at which children are seen, and like that, children with very low chances of autism sit in a pipeline waiting to meet some kind of expert. Not,” she said.

Source: www.nbcnews.com

Research indicates that intermittent fasting may have a major impact on slowing down hair growth

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Intermittent fasting can be effective for weight loss, but it can also have negative effects on hair growth, as shown in a recent mouse experiment conducted by researchers at Westlake University in China. The study found that mice undergoing intermittent fasting experienced improved metabolic health but showed delayed hair regrowth. This link between restrictive eating and hair regrowth was also observed in a study published in Cell.

While similar effects may occur in humans, they are typically less severe due to differences in metabolic rate and hair growth patterns. Nevertheless, it is important to be aware of the potential unintended consequences of intermittent fasting, as highlighted by senior author and stem cell biologist Dr. Bing Zhang.

Further research is needed to fully understand the effects of fasting on hair growth, as current studies have primarily focused on its benefits for blood, muscle tissue supply, and metabolism. The research team at Westlake University conducted experiments on mice to explore the impact of intermittent fasting on hair regrowth, with findings suggesting that prolonged fasting stresses hair follicle stem cells, leading to delayed hair growth.

A small clinical trial involving 49 healthy young individuals showed that time-restricted eating with 18 hours of daily fasting reduced hair growth by an average of 18 percent. However, the researchers caution that the study’s small sample size and short duration may yield different results in larger-scale studies.

Future research will investigate how fasting affects other types of stem cells in the body and its implications for wound healing speed. Despite the potential drawbacks, intermittent fasting remains a popular and beneficial practice for many individuals.

Source: www.sciencefocus.com

Dyson reveals the mystical properties of mushrooms in combating frizzy hair | Dyson Ltd

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Mushrooms have become a popular health trend, making their way into coffee, supplements, and even beer. Dyson recently unveiled their potential use for taming frizzy hair by utilizing chitosan, a fungus found in oyster mushrooms often used in skincare products.

This innovative ingredient, chitosan, is the key component of Dyson’s new styling cream and serum, both priced at £50 for 100ml and claimed to reduce frizz by up to 50%. It provides a delicate yet strong hold, enabling natural movement while keeping the hair in place.

Dyson’s engineers conducted thorough testing to determine the ideal chitosan percentage for long-lasting flexible hold. The products are packed with the power of up to eight oyster mushrooms, offering a unique approach compared to traditional polymer-based hair products.

James Dyson, the company’s chief engineer, explained that their complex polymers create flexible bonds that enhance the hold, movement, and shine of the hair, setting them apart from competitors. Dyson has a history of successful innovations, including bagless vacuums and bladeless fans, and is now venturing into the beauty market with products like the “supersonic” hair dryer.

While Dyson leads the way in harnessing the benefits of fungi, other companies are also exploring the use of fungal ingredients in various products. The growing popularity of mushrooms has prompted consumer advocacy groups to investigate the true impact and benefits of this trend in the beauty and health industries.

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Though mushroom products have potential benefits, consumer advocates warn that there is not enough evidence to support their effectiveness or health benefits, cautioning consumers against assuming their advantages without thorough research.

Source: www.theguardian.com

A cost-effective, all-natural remedy for hair loss may have been uncovered by scientists

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Scientists have made a groundbreaking discovery in the hair loss industry by finding that a naturally occurring sugar in the human body, 2-deoxy-D-ribose (2dDR), could be the key to combating male pattern baldness.

The study, published in the journal The forefront of pharmacology, revealed that this natural sugar treatment is as effective as current FDA-approved treatments with fewer side effects.

Research co-author, Professor Sheila McNeill, highlighted the potential of 2dDR in increasing blood supply to hair follicles and promoting hair growth. The study was initially focused on wound healing, where accelerated hair growth was observed around sites treated with 2dDR.

Testing in mice showed that 2dDR Gel was 80-90% as effective as minoxidil, a common FDA-approved hair loss treatment found in products like Rogaine and Celoxidil. The discovery offers a promising, safer alternative with fewer side effects, as 2dDR is naturally occurring in the body.

Experts, such as Professor Muhammad Yar, stressed the potential benefits of 2dDR in stimulating blood vessel growth, crucial for healthy hair follicles, and promoting hair growth.

While the research is still in early stages, it could provide hope for those suffering from hair loss conditions like chemotherapy-induced alopecia. More studies are needed before 2dDR-based treatments become available, but the results so far are promising.

For men dealing with hair loss, this discovery offers a ray of hope for an effective, natural, and non-invasive treatment option. Further research is warranted to explore its effects on human hair growth and follicle health.

Learn more from our experts:

Sheila McNeill: Professor Emeritus of Tissue Engineering with a focus on translating research into clinical practice.

Muhammad Yar: Associate Professor with expertise in tissue engineered skin and targeted drug delivery.

Claire Higgins: Lecturer specializing in tissue engineering and regenerative medicine, focusing on skin and hair follicles.

Read more:

Source: www.sciencefocus.com