Over 50% of the world’s population experiences at least one cavity in childhood, increasing to over 90% in adults. Using a fluoride gagging agent, brushing and flossing twice daily and getting fillings as needed is a standard practice to maintain good dental hygiene. Still, dentists fill more than 100 million cavities around the world each year, on average. What if there is a way to prevent it? and Reverse cavity? Dental researchers recently tested a new method of restoring the structure of teeth before major damage occurs.
Our teeth are made up of minerals made up of calcium and phosphates. When the acids and bacteria in our mouth break down these minerals, our teeth experience Demineralisation. When dechlorination drills holes in the protective layer outside the tooth, a cavity forms; enamel. If left untreated, these holes will deepen and slowly collapse over time the enamel and remaining teeth.
Brushing teeth and using mouthwash can clean acids and bacteria from the mouth to prevent the initial cavity, but dental researchers want to demineralize and therefore reverse the cavity. Tooth-like minerals line themselves up in shapes similar to snowflakes and diamonds. Crystal-like structure. They also tend to complete their own patterns by fusing firmly with the surrounding minerals. Therefore, researchers hope to use this natural process to reconstruct dental minerals into their crystal-like structures.
One way to encourage scientists to begin reconstructing teeth is to use small chains of molecules that form proteins. peptide. Scientists use a specific peptide called An Enamel-binding peptide Or EBP can help bind calcium and phosphate to crystallize. When you soak your teeth in a container filled with EBP, the minerals bind to it. Minerals from the solution do not stick to the teeth without EBPS. This makes these peptides an important component in crystal growth.
This knowledge led Japanese researchers to bind teeth with minerals, assuming that they could be soaked in EBP called wgnyayk and immersed in calcium and phosphate solutions. If this process works, build or effectively return the hard surface of the teeth. reminderalize Its enamel.
To test this idea, the researchers acquired 30 cow teeth and randomly separated them into three groups. They degrined the enamel of each tooth by placing it in a solution containing acetic acid at a pH of 4.5 for 7-9 days to mimic how natural tooth enamel fades. After this process, the scientists coated two groups of teeth with wgnyayk peptides and did not leave the other groups. They immersed them in a remineralization solution containing monopotasium phosphate and buffer at a pH of 7. The researchers also added a green pigment to the solution that brightens and brightens the harder the enamel surface. The more dense the minerals, the more intense the enamel and brighten the teeth.
Scientists analyzed teeth soaked in WGNYAYK peptide solution under a laser microscope. They found that the higher the concentration of the peptide solution that had soaked in the teeth, the brighter fluorescent green. They explained that this correlation means that the combination of peptide and mineral baths partially restored tooth enamel.
The researchers considered their experiment a success because the EBP they tested promoted dental remineralization. Next, they are trying to create a local application of this EBP for clinical research. They warned that before this EBP is brought to trial in humans, scientists should investigate the composition and potential adverse effects of reinserted teeth. Still, the researchers concluded that their success was a step in the right direction for dentistry. Future testing will check whether EBP treatment is effective in human teeth as well as in cow teeth.
Post view: 83
Source: sciworthy.com
