Exploring the Impact of Illness on Our Lives: A Captivating Yet Imperfect Read

Healthcare professionals in protective masks stand near a triage tent for possible COVID-19 patients outside Santa María Hospital in Lisbon on April 2, 2020. Over 500 lives have been claimed by COVID-19 in Portugal, with more than 6,000 confirmed cases. (Photo by PATRICIA DE MELO MOREIRA/AFP via Getty Images)

Healthcare professionals stand near a COVID-19 triage tent in Lisbon, Portugal, April 2020.

Patricia de Melo Moreira/AFP via Getty Images

The Great Shadow
by Susan Wise Bauer, St. Martin’s Press

Publishing a book on the history of disease seems timely given the ongoing challenges with public health. As we face yet another tough winter in the Northern Hemisphere, we reflect on the previous harsh winter during the COVID-19 pandemic. Our vulnerability to illness has never been more evident.

Introducing The Great Shadow: A History of How Disease Shapes Our Actions, Thoughts, Beliefs, and Purchases, authored by Susan Wise Bauer. This work chronicles how disease influences individual lives and collective societal behaviors over centuries. From our guilty pleasures to our shopping habits, microbial influences are always at play.

However, the subject isn’t entirely new; similar works have emerged since the pandemic, such as Jonathan Kennedy’s comprehensive essays, along with updated versions of Sean Martin’s A Short History of Disease and Frederick F. Cartwright and Michael Biddis’s Disease and History. So, what sets this work apart?

The distinction lies in Bauer’s emphasis. She explores the shift from the “Hippocratic universe” to our contemporary understanding steeped in “germ theory.” The former relies on antiquated beliefs regarding bodily humors and inner balance, while the latter focuses on scientific evidence.

A key revelation of this book is the prolonged timeline for this transition; the acknowledgment that microbes cause disease took centuries to establish and only gained traction in the late Victorian era—resulting in millions of unnecessary deaths.

Yet, have we completely moved past Hippocratic medicine? The Great Shadow doubles as a discussion piece. Each chapter unveils a timeline, navigating through urbanization, the Black Death, and the trenches of World War I, before linking historical events to current beliefs surrounding disease.

At its best, this research provokes contemplation. Are we surprised that 19th-century anti-vaccination advocates resemble today’s skeptics? At its worst, some discussions may prove perplexing. For instance, Bauer confesses that following COVID-19, she avoided checkups out of fear of being criticized for her weight gain—a worrying reflection on the pressures surrounding health discussions.

Nevertheless, glimmers of insight are present in The Great Shadow. Despite moments of verbose writing, Bauer efficiently crafts narratives from historical archives. Her account of early germ theory proponents like Alexander Gordon and Ignace Semmelweis, often marginalized for their views, merits cinematic adaptation.

The final, memorable aspect of this book discusses our shift from superstition to science, presenting the current crisis termed the Third Epidemiological Transition. Bauer notes that we face not only epidemic failures with antibiotics but also the rapid emergence of novel diseases for which vaccines and treatments are yet unavailable, facilitated by modern global travel.

Peter Hoskin is the Books and Culture Editor at Prospect magazine.

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Source: www.newscientist.com

Protecting Lives: How Subsidence in River Deltas Increases Flood Risk for Millions

Chao Phraya River Delta

Thailand’s Chao Phraya River Delta: Rapidly Sinking

Channon Kanjanavasoonthara/Getty Images

The Chao Phraya River Delta, one of the most economically and environmentally vital deltas globally, is sinking at alarming rates, threatening millions with severe flooding. Recent satellite data analysis reveals that subsidence in river deltas is becoming a greater danger to local communities than rising sea levels.

Approximately 500 million people inhabit this delta, including some of the world’s most impoverished communities. This expansive lowland area houses 10 megacities, each boasting populations exceeding 10 million.

Manuchel Shirzai and his team at Virginia Tech researched subsidence rates in 40 global deltas, including the Mekong, Mississippi, Amazon, Zambezi, Yangtze, and Nile rivers.

Shirzaei noted, “As deltas sink, global sea levels are also rising by about 4 millimeters annually, creating a compounded risk of flooding.”

The research utilized data from 2014 to 2023 collected by the European Space Agency’s Sentinel 1 satellite radar, which can detect changes in ground distance with precision up to 0.5 mm. Across the 40 studied deltas, over one-third showed signs of subsidence, with more than half of the area affected in 38 of these regions.

“In numerous cases, land subsidence contributes more to relative sea level rise than the ocean itself,” Shirzaei asserted. “In 18 out of 40 deltas, average subsidence rates surpass sea level rise, with the impacts being significantly pronounced in areas located less than 1 meter above sea level.”

The Chao Phraya Delta, where Bangkok is situated, ranks as the most affected among 40 nations concerning subsidence rates and impacted areas. Here, the average subsidence rate reaches 8 mm per year, which is double the global average for sea level rise, with 94% of the delta sinking at rates above 5 mm per year.

As a result of combined land subsidence and sea level rise, Bangkok and the Chao Phraya Delta confront a formidable projected sea level rise of 12.3 millimeters per year. Other cities like Alexandria in Egypt and Jakarta and Surabaya in Indonesia share similar predicaments of rapid land subsidence.

The researchers analyzed three major anthropogenic pressures: groundwater extraction, sediment alteration, and urban growth to assess their impacts on delta subsidence. Shirzaei explained that upstream dams, levees, and river engineering limit sediment input, which is crucial for delta maintenance, while urban development escalates pressure on delta surfaces and heightens water demand, furthering groundwater depletion.

Among these factors, groundwater extraction poses the most significant impact overall, although specific delta areas may be more influenced by sediment shifts and urbanization, the study found.

Shirzaei emphasized, “It would be misguided for policymakers to concentrate solely on sea level rise due to climate change and overlook local land subsidence. Unlike global sea level rise, human-driven land subsidence can often be tackled locally through groundwater regulation, managed aquifer recharge, and sediment management.”

He also pointed out that water-intensive facilities, such as data centers, may exacerbate this issue. “Our findings reveal that groundwater extraction is a major contributor to accelerated land subsidence in numerous delta regions, which can worsen when such facilities depend on local water sources,” he remarked.

In already vulnerable areas like the Mekong Delta, increasing water demand may hasten land subsidence, jeopardizing drainage, flood protection systems, and the durability of crucial infrastructure. “This doesn’t suggest data centers should be avoided altogether in the delta, but they must prioritize groundwater conservation, minimize overall water use, and take land subsidence into account,” said Shirzaei.

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Source: www.newscientist.com

Chris McCausland: A Surprising Exploration of How Technology is Transforming Lives for People with Disabilities

WThe ash processor has allowed women to engage in exhausting jobs that drain their leisure time. While social media sparked one revolution, it also led to the destabilization of democracies worldwide. Now, with the rise of AI, it appears that screenwriters might be among its primary targets for replacement. It’s easy to succumb to techno-pessimism; however, the new documentary *Seeing into the Future* (Sunday, 23 November, 8 PM, BBC Two) offers a fresh perspective. For individuals with disabilities, tech advancements are already making a significant impact, and this is just the beginning.

Hosted by comedian and *Strictly* champion Chris McCausland, who is visually impaired, the show features surprisingly captivating moments early on, such as how he utilizes his smartphone. Essentially, it serves as his eyes and voice. “What T-shirt is this?” he inquired while holding up the item. “Gray T-shirt with Deftones graphic logo,” his phone declared. It even informs him if his shirt requires ironing. However, McCausland was more curious about the origins of this technology and traveled to the U.S. to explore developments in the homes of tech leaders.

He visited Meta’s facility to test smart glasses. Personally, it felt as if he were either in a lair of a fictional villain or wandering around a castle for treats. This perspective reflects my lack of immediate necessity for such tech, as documentaries aim to unveil possibilities rather than highlight deficiencies. I imagine Mr. Zuckerberg isn’t lurking in a lab with pets or spinning in an egg chair.

I enjoy broadening my viewpoint. Although a button-less glass screen appears to be an exclusive gadget, McCausland acknowledges that his smartphone has turned into the most accessible device he has ever encountered. He expresses excitement about a device he whimsically refers to as Metaspec. This device is always active, offering live video descriptions and identifying what he’s viewing. It functions like a phone but is more like a wearable gadget. “A blind person will never have both hands free,” he remarks.




McCausland and Meta’s Vice President of Accessibility and Engagement Maxine Williams test out smart glasses.
Photo: BBC/Open Mic Productions

At MIT, he learned about nanotechnologies that may enable molecular devices to repair bodily cells. He experimented with a bionic walking aid that attaches to the calf to provide the wearer with additional strength, similar to the knee brace Bruce Wayne wore in *The Dark Knight Rises*. The most significant moment for him was traveling in a self-driving car, marking his first experience of riding alone in a vehicle.

Autonomous vehicles are anticipated to debut in the UK next spring (which feels like a long wait). My instinct is to label them as NOPE. Nevertheless, McCausland noted, “it’s not terribly different from trusting an unfamiliar driver.” These extraordinary cars come equipped with rotating radars that compute data, including the speed of light, to create a 3D model of their surroundings instantly. They might even feature gullwing doors. McCausland appreciated the self-operating handle, which adds a touch of intrigue. Coolness is likely the second best drive an engineer can pursue, the first being ensuring equal access to dignity and independent living. I must clarify that my skepticism doesn’t stem from just a general mistrust of technology; it leads to a mistrust of profit-driven big tech companies in considering public welfare or accountability.


The documentary also offers similar moments of delight, showcasing cultural disparities across the Atlantic. The participants are not merely Americans but the innovative minds of San Francisco. Unintentional comedy is enhanced by McCausland’s dry wit; even while discussing a blood-based computer with a nanotechnologist that could potentially restore eyesight, he seems more inclined to grab a pint at the pub than delve into futuristic devices.

The technology portrayed is distinctly American. “Can you hear the plane?” McCausland urged Zuckerberg to test out the glasses. “Yes, I can see the plane in the clear blue sky,” a serious, bespectacled participant replied. McCausland then exchanged a wry look with his camera crew, quipping, “Do they appear to know what they’re doing?” Judging by their gear, it seems they are indeed professionals. While gadgets become more capable of divine-like capabilities, a layer of skepticism remains, even when wearing Batman’s leg braces.

Source: www.theguardian.com

Guide #218: For Gen Z, YouTube is More Than an App—It’s the Background of Our Everyday Lives

BMonths pass with minimal updates on streaming platforms surpassing traditional television. YouTube remains the leader with 2.5 billion viewers monthly. For those of us around 28 and younger, YouTube is less of an application and more of a response to the omnipresent background noise of today’s life. While my mother fills the house with Radio 4 or has BBC News flickering in the background, I’m engrossed in a video essay on Japan’s innovative urban planning. It’s not that I entirely avoid traditional TV (though I primarily access it through various streaming services), but after a long day, the thought of enduring another hour of intense programming feels overwhelming. More often than not, I gravitate towards YouTube, meaning it’s improbable that we’re viewing the same content.

When Google acquired the platform for $1.65 billion in 2006, the amount seemed outrageous. Many critics doubted whether any video platform could justify such a valuation. The reasoning was straightforward: Unless YouTube could eclipse television, it would never attain that worth. Fast forward nearly two decades, and that perspective significantly underestimates YouTube’s evolution. It hasn’t merely replaced TV; it has also pioneered entirely new content formats, such as vodcasts, vlogs, video essays, reaction videos, ASMR, and its controversial counterpart, mukbang. The platform has effortlessly adapted to emerging trends, establishing an alternate ‘online mainstream’. Long before podcasters, TikTokers, substack writers, or influencers emerged, there were YouTubers.

I began my YouTube Premium subscription during the COVID-19 lockdown when I found myself with ample time, no commute, and extra cash. Currently, it’s the only subscription I don’t question in terms of value; instead, I contemplate whether it significantly impacts my personal growth. Regrettably, my gym membership doesn’t match this criteria.

The standout advantage of a premium subscription is the absence of ads. Additionally, the smart downloads feature, which automatically curates episodes for your queue based on viewing habits, has been invaluable during lengthy subway rides. I rarely experience boredom nowadays. On my daily commute instead of staring vacantly out the window, I enjoy sports highlights or listen to podcasts. I find myself immersed in YouTube without a second thought.

Donald Trump (right) appears on Joe Rogan’s podcast on YouTube. Photo: https://www.youtube.com/watch?v=hBMoPUAeLnY

I feel a bit sheepish admitting that a random burst of short stories about guitar instructors and teenage garage bands reignited my passion for playing. It’s akin to confessing you met your significant other on Hinge. Yet, that’s precisely the point. YouTube has democratized expertise in a manner that traditional media never achieved. Moreover, it aligns with the social norms around media consumption on mobile devices. I wouldn’t dare watch a Spielberg or Scorsese film on a 6-inch screen; it feels disrespectful to the artistry. However, behind-the-scenes footage and promotional tour clips? That’s the ideal use for YouTube.

I indulge in a mix of homegrown YouTube creators, such as Amelia DiMoldenburg’s Chicken Shop Date, XXSyHighroller for NBA analysis, Tifo Football for tactical breakdowns, and Happy Sad Confused for film interviews. Additionally, I consume a steady stream of content initially designed for television and print but now reaches vast audiences through YouTube, including shows like Graham Norton, Saturday Night Live, and fellow journalists like Owen Jones and Mark Kermode. Sports highlights also thrive on the platform, providing an unparalleled convenience that traditional broadcasters struggle to offer, especially regarding paywalled sports like cricket and the NFL, which demand significant financial and temporal investment to access live.

Nevertheless, this convenience isn’t without its challenges. YouTube’s intensely personalized algorithms ensure that everyone’s viewing experience is unique. While previous generations could bond over the question, “Did you catch that last night?” now people are entrenched in their individual algorithmic bubbles. Despite the abundance of choices, we’ve lost the shared cultural experience. Even YouTube’s significant moments are splintered in a way that Saturday night television never was. When far-right politicians lament societal divisions, their focus might be better directed toward our viewing behaviors instead of immigration concerns. My enjoyment of algorithms might be more aligned with a 28-year-old in Bangalore than with the 45-year-old neighbor next door.

While this reality can be unsettling, there’s a noteworthy exception. Although YouTube intensifies viewing discrepancies across many demographics, it has forged a near-monoculture among younger audiences. Figures like Joe Rogan, Theo Von, Rex Fridman, and a revolving group of intellectuals, including podcasters aligned with President Trump and the late Charlie Kirk, have fostered a pervasive and relaxed dialogue among men in my age group. Although YouTube has democratized access to long-form discussions in enriching ways, it has also facilitated a pipeline for increasingly detrimental content. The platform’s algorithms not only highlight what piques your interest but also what captures your attention longer, which aren’t always the same. This phenomenon tends to elevate extreme viewpoints and fringe theories, leading viewers on a gradual journey from innocuous to genuinely harmful misinformation without them realizing it. Furthermore, it’s challenging for communities to self-regulate since everyone within a demographic shares a similar experience.

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Recent statistics show that YouTube users consume over 1 billion hours of content daily around the globe. For better or worse, YouTube has emerged victorious, and I’m mostly okay with that. You might want to consult your outdated TV guide to figure out what’s on BBC Two at 9 PM. However, perhaps we should reassess the balance—not only between YouTube and competing platforms but also between YouTube and everything else. I’m uncertain about the solution…but I’m fairly confident there’s a video essay that can tell me what I should think.

If you’d like to read the full edition of this newsletter, subscribe to receive the guide in your inbox every Friday.

Source: www.theguardian.com

Enshittification: Cory Doctorow’s 2022 Term Explaining How Tech Companies Have Deteriorated Our Lives

Does your phone feel less capable than it used to? Enshittification might be the culprit

Hector Retamal/AFP via Getty Images

Enshifted
Cory Doctorow (MCD Books)

“Enshittification,” much like “shrinkflation” and “greenwashing,” is a newly coined term that feels familiar, perfectly expressing a widespread yet subtle issue.

We’re acutely aware that websites and apps often deteriorate or become worse over time as their owners exploit users for profit. This is visible everywhere, from Instagram swapping your chronological feed for a mashup of influencer content to Apple compelling users to upgrade by limiting repair options.

Cory Doctorow introduced the term in 2022 and elaborated on it in his recent book. More information: Why everything suddenly went bad and what to do about it serves as both an analysis and a call to action.

The strategy behind enshittification is for platforms like Facebook to establish and provide excellent services. Users flock to them for convenience and enjoyment. The company then waits until we are deeply connected—friends, local groups, schools, etc.—making it cumbersome to leave.

Once the user base becomes substantial, advertisers get locked in as well. The company then shifts focus to profits, inundating services with ads and algorithms, leading to a decline in user experience. This creates pressure on advertisers. The platform then becomes toxic, primarily benefitting shareholders, and users find it difficult to quit. As Doctorow states, we are trapped in a decaying entity.

In the past, poor businesses would have faced market consequences. If a café serves bad coffee, we’d simply find another. Today, however, tech companies have formed monopolies, making substantial profits that allow them to sustain their dominance. They purchase competitors merely to shut them down, lobby for lenient regulations, and secure exclusive contracts. (For instance, Google pays Apple $20 billion annually to remain the default search engine in Apple’s Safari browser.)

Enshifted Companies that seemingly harvest excessive personal data expose industry secrets, knowing they’ll charge more for goods during paydays since consumers are less likely to negotiate. Or companies deploy algorithms to suppress gig economy wages or implement keystroke monitoring systems that alert supervisors when we pause typing.

Although these negative aspects aren’t entirely new to readers, consuming them in large quantities can leave a sour taste. They can even lead intelligent individuals to resent themselves for being misunderstood in various ways.

Indeed, the goal is simply to do what the company was designed to do: maximize profit. However, with advances in computers, algorithms, and the Internet, things have spiraled out of control, allowing for techniques far more sophisticated than those available just a decade ago.

Doctorow cautions that regulators meant to protect us are often outmatched by the companies they monitor. Yet, he firmly believes they are part of the solution.

While there have been favorable developments in the European Union and under President Joe Biden in the U.S., substantial work remains to be done, as tech companies may innovate ways to harm us more quickly than can be counteracted. We can demand more accountability from politicians, and well-crafted legislation supported by effective regulators can help.

However, the potential power of boycotts remains largely unaddressed—tech companies need us more than we need them. It’s feasible to abandon social media, favor local businesses, and utilize ethical search engines. The more individuals take such actions, the likelier others will follow.

Whether it pertains to travel, clothing, or food, many of us attempt to “vote” with our wallets. Perhaps it’s time we extend this practice to our online choices.

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Source: www.newscientist.com

Skeleton ‘Pregnancy Test’ May Unlock Secrets of Ancient Maternal Lives

Skeleton of a woman holding a baby in her left arm, interred in an Anglo-Saxon cemetery in Screnby, England

Dr Hugh Wilmot, University of Sheffield

Researchers are now investigating ancient pregnancy tests undertaken on women from centuries past.

For the first time, scientists have identified levels of estrogen, progesterone, and testosterone in remains of women from the 1st to the 19th century. Some of these women were entombed with their unborn children. This revelation indicates that historic bones and teeth can retain identifiable traces of specific sex hormones, which might aid in discerning which individuals at archaeological sites were pregnant or had recently given birth at the time of their demise, according to Amy Barlow from the University of Sheffield, UK.

“The physiological and emotional impacts of pregnancy, miscarriage, and childbirth carry profound significance for women, yet they remain largely unexplored in archaeological records,” she notes. “This technique could revolutionize how we comprehend the reproductive narratives of ancient populations. We’re genuinely excited about it.”

Establishing pregnancy in ancient individuals can be challenging, particularly if the fetus lacks a visible skeleton. Even second- and third-trimester fetuses may be overlooked due to their bones resembling those of the mother’s hands, often placed on the abdomen during burial.

Contemporary pregnancy tests evaluate hormone levels such as hCG in blood or urine. However, hCG degrades rapidly, leaving minimal evidence in the body.

In contrast, progesterone, estrogen, and testosterone can persist in tissues for extended periods. Recent studies have demonstrated that these steroid hormones are also present in human blood, saliva, and hair. Samples from long-buried Egyptian mummies.

To explore the likelihood of identifying ancient pregnancies, Barlow and her team analyzed rib fragments and one neck bone from two men and seven women interred in four British cemeteries. They also examined teeth from another male.

Two of the women had fetal remains discovered within them, and another two were buried alongside their newborns. The gender of the others was established through DNA analysis.

The research team ground each sample into powder and employed chemical techniques to extract the steroid hormones. Laboratory tests subsequently identified the estrogen, progesterone, and testosterone levels in each of the 74 samples.

Estrogen was only found in four samples, without a discernible pattern. This may be due to its quicker breakdown compared to progesterone or testosterone, which may not accumulate as efficiently in tissues.

However, between the 11th and 14th centuries, heightened levels of progesterone were discovered in the spines of young women who died while carrying full-term fetuses. A later pregnant woman interred in the 18th or 19th century also exhibited elevated progesterone in her ribs. Moderate progesterone levels were noted in the dental plaque of two women buried with their infants during the 5th or 6th century.

Interestingly, no testosterone was detected in the bones or teeth of these four women. However, one woman who was buried with her premature infant had trace amounts of testosterone in her dental plaque. In contrast, three unrelated women from 8th- to 12th-century sites and Roman tombs showed testosterone in all layers of their ribs and teeth.

Low testosterone levels are known to play a crucial role in women’s health, so its discovery in these samples isn’t unexpected, Barlow states. “However, the absence of testosterone may indicate that she was recently or currently pregnant at the time of her death,” she adds.

“This intersection of archaeology and hormone science is exhilarating and unforeseen,” states Alexander Komninos from Imperial College London. “These methods will enhance our ability to detect pregnancy in human remains with greater precision, providing deeper insights into ancient pregnancies.”

Nevertheless, while the findings show promise, additional research is essential to clarify many aspects, according to Barlow. For instance, moderate progesterone levels were frequently found in the bones and inner teeth of men, but the reasoning behind this remains unclear, she comments. “Interpretation is quite cautious at this junction.”

Walking through Hadrian’s Wall and Rome’s innovations: England

Join this immersive walking tour along Hadrian’s Wall, one of Great Britain’s most iconic ancient structures and a UNESCO World Heritage Site.

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Source: www.newscientist.com

Good Parents and Devoted Partners Enjoy Longer Lives

Recent studies suggest that our evolutionary predecessors may have prioritized gender over survival, potentially explaining why men tend to have shorter lifespans than women.

Historically and globally, men usually live shorter lives than women. To understand the reasons behind this evolutionary trend, researchers at the Max Planck Institute in Germany focused on insights from our animal relatives rather than solely examining human history.

Their study, published in Advances in Science, analyzed over 1,000 animal species to identify evolutionary traits associated with gender differences in lifespan.

The team discovered that while genetics plays a role, monogamy is also significant in influencing male lifespan. In contrast, parenting may contribute to women’s longer lives.

In humans, women live on average 5 years longer than men, but this trend is not unique to our species. In fact, 72% of mammals show that females live on average 12% longer than their male counterparts, with some female moose living more than twice as long as males.

However, this pattern doesn’t hold true across all animal species. In birds, males frequently outlive females.

A primary explanation lies in chromosomes, which are fundamental to gender differences. Female mammals possess two X chromosomes, whereas males have a shorter Y chromosome.

According to Dr. Johanna Staerk, the lead researcher, “Men’s single X chromosome means they are particularly susceptible to harmful mutations, as they lack a second copy for compensation,” she explained to BBC Science Focus.

“The ‘toxic Y’ hypothesis posits that the Y chromosome may harbor genetic factors that negatively influence health and aging.”

Conversely, in birds with ZW chromosomes, males have two Z chromosomes while females possess one Z and a truncated W chromosome. However, if chromosomes were the sole factor, males would live longer in all bird species.

“Some species demonstrate the opposite of what we expect,” Staerk noted. “In many birds of prey, for instance, females exhibit longer lifespans than males. This indicates that sex chromosomes alone cannot explain the patterns.”

What other factors are at play? Researchers believe that the issue involves more than mere genetic sex; it includes reproductive strategies. While birds typically show monogamous behavior, only a minority of mammals do.

“Males frequently bear the burden of mating endeavors,” Staerk said. “To attract mates, they develop traits like big horns and manes that require energy investments, increasing their risk of injury and reducing their lifespan.”

The effort to develop large horns and then engage with rivals means that male moose live only half as long as females – Credit: Getty Images

Attractive and robust males tend to father more offspring, but the biological resources required for developing larger muscle and horn structures negatively impact their lifespans. In monogamous species, the competition is less intense, allowing males to avoid such trade-offs during evolution, resulting in smaller lifespan gaps between sexes.

One intriguing finding highlighted how parenting influences lifespan. While one might assume that parental responsibilities detract from longevity due to energy exertion, the opposite was observed: caregiving genders often live longer, especially in species like primates, where offspring require extended care.

For example, a mother chimpanzee may care for her young for up to a decade. This implies that mothers who live longer are better positioned to nurture their offspring.

“Extended lifespans enable caregivers to obtain selective advantages by ensuring that their young reach maturity,” stated Staerk.

However, it remains challenging to determine definitively whether the longevity benefits stem from parenting alone or from monogamy.

Ultimately, being a dedicated partner and parent seems crucial to achieving a longer lifespan for men, particularly from an evolutionary standpoint.

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Source: www.sciencefocus.com

This Timeless Blue Sea Creature Has Rescued Countless Lives

Long before dinosaurs roamed the Earth, peculiar creatures abandoned their journeys across the ocean floor. They resembled beings adorned with spiked helmets and had eyes positioned on top, along with sharp tails extending behind them.

Today, horseshoe crabs still exist and belong to the animal order known as Xiphosura, derived from ancient Greek, meaning “sword” and “tail.” Despite their name, they are more closely related to spiders than to crustaceans.

Fossils of horseshoe crabs date back to the Upper Ordovician period, approximately 450 million years ago. Their descendants—four existing species—have undergone significant changes in appearance, earning them the title of “living fossils.”

Despite their ancient lineage, horseshoe crabs are crucial in today’s world. Most people eventually come into contact with life-saving doses of bright blue blood derived from these creatures.

The blue hue comes from Hemocyanin, a pigment responsible for oxygen transport, which is analogous to red hemoglobin found in vertebrate blood.

Importantly, it also harbors their blood. Amebocytes, a powerful immune cell are exceptionally sensitive to harmful toxins produced by bacteria. Endotoxins, prevalent in the environment, are resistant to standard sterilization methods.

Should a vaccine contain endotoxins, it could trigger a dangerous reaction historically known as “injection fever.”

Previously, tests were conducted by injecting a vaccine batch into a living rabbit; if any exhibited a fever, it signified contamination.

In the 1960s, American marine biologists observed that the blue blood of horseshoe crabs coagulated instantly upon contact with fever-inducing endotoxin. This mechanism allows horseshoe crabs to encapsulate bacteria by forming clots around them, proving beneficial for human applications.

Now, rather than injecting rabbits, hundreds of thousands of horseshoe crabs are harvested from the ocean each year, with a third of their blood extracted to test for endotoxins in intravenous medications and medical implants.

Many people eventually encounter the vibrant blue blood of a life-saving horseshoe crab – Image credit: Jurgen Freund/Naturepl.com

The demand for blue blood has surged, especially with the competition surrounding the development of the COVID-19 vaccine.

Not all horseshoe crabs survive the blood collection process; approximately 15-30% do not. Conservationists are advocating for synthetic alternatives to blood tests.

In the 1990s, researchers in Singapore developed a method to create synthetic endotoxin detection using a compound based on horseshoe crab DNA. Currently, various alternative compounds mimic this reaction without utilizing horseshoe crab blood.

Although regulatory processes have been sluggish, these new compounds received approval for use in Europe in 2016 and 2024. Nowadays, pharmaceutical companies are increasingly opting for synthetic methods.

This development bodes well not just for horseshoe crabs but also for other species reliant on them. Each year, thousands of horseshoe crabs come ashore on sandy beaches along North America’s East Coast, particularly in Delaware Bay, where eggs are laid near Philadelphia.

A single female lays around 4,000 eggs, many of which become vital sustenance for migratory birds like the red knot, which journey between South America and the Canadian Arctic.


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Explore our ultimate Fun facts for more amazing science insights.


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Source: www.sciencefocus.com

Blowwinner Review: Engaging and Powerful Books Uncover the Biases That Influence Our Lives

Despite significant changes since the 1950s, women continue to shoulder more domestic responsibilities

ClassicStock/Alamy

Earn money
Melissa Hogenboom (Canongate Books, August 14th, UK)

Why do individuals without jobs feel uplifted when their partners are unemployed? How do women develop empathy as they mature? Why does a disordered room appear untidy when it belongs to Jennifer, but not John? These pressing issues are explored by Melissa Hogenboom in her book Earn money: and other power imbalances that affect your life. The book uncovers the hidden power dynamics and subconscious cognitive biases that influence our behaviors and choices.

This narrative goes beyond individual actions; it serves as a well-researched examination of how stereotypes and unseen disparities shape everything from household chores to career advancement.

Fair warning: it may provoke anger—especially regarding household responsibilities. Studies indicate that in heterosexual relationships, domestic duties are typically assumed by women unless addressed directly. Women tend to take on more odd jobs, even when they log more hours at work. Hogenboom notes that some studies imply this might be an unconscious “compensation” strategy for unconventional family dynamics.

Gender biases begin early in life. Mothers engage more extensively during pregnancy, whereas fathers share more about their feelings with daughters and their achievements with sons. Studies have found that fathers react more deeply to their daughters’ emotions.

This reinforces the notion that women are inherently nurturing or empathetic—a stereotype that influences various realms, from parenting to leadership roles. In fact, while empathy can be partially genetic, there are no innate differences between genders.

When societal pressures are lifted, a new truth may surface. As highlighted in a case study of same-sex male couples, “The assumption that if parents remain at home without societal pressures, they will naturally share childcare responsibilities is quite misguided,” says one participant. “If my partner had suggested returning to work within a fortnight, I would have been furious.”

Hogenboom also points out that mothers in same-sex relationships may encounter fewer career obstacles after maternity leave compared to those in heterosexual partnerships, indicating that maternity alone does not dictate such penalties.

The myth of mutuality deludes couples that they have achieved a good balance of labor.

The book sheds light on the intangible forces predominantly managed by men: hidden inequalities often perceived as normal. At times, Hogenboom asserts, “Women, here’s the evidence you need to justify your exhaustion.”

Notably, the persistent challenges faced by men who seek to address these power disparities are highlighted. A study referenced by Hogenboom found that men requesting part-time roles often face skepticism more than women and encounter taunts like “Where’s your mom?” They often struggle to be taken seriously and may be viewed as less committed, complicating their social dynamics within parenting communities.

Couples who believe they have achieved equality might be surprised by how Hogenboom reveals these unseen dynamics of authority. She argues that systematic inequalities represent a dominant form of power in relationships, often overlooked—even by the couples who experience them.

The perception of mutuality can lead couples to falsely believe they maintain an even distribution of responsibilities. However, they may be deceiving themselves if they don’t consider whose needs are genuinely met and who does the work. For instance, your partner might “cook all the meals,” but have you handled the meal planning, grocery shopping, cleaning, and budgeting?

Fortunately, Hogenboom offers actionable advice. If you find yourself overwhelmed, she suggests handling tasks comprehensively: “It eliminates hidden burdens when ownership of the entire task is taken.”

Her recommendations provide a much-needed relief amidst the wealth of data presented. While authoritative and insightful, Hogenboom’s writing style leaves little room for reflection.

However, moments of reflection are necessary. Earn money constructs a convincing argument to recognize the influence of concealed power dynamics and informs how to address them. This leads to fairer relationships and more successful careers, potentially saving marriages.

Helen Thomson is an author based in London.

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Harnessing the Power of Music to Transform Our Lives

A new scientist. Science News and Long read from expert journalists covering science, technology, health, and environmental developments in various media.

Music transcends mere entertainment; it serves as a remarkably effective tool for regulating mental states. Society must acknowledge the therapeutic potential of music, extending its use beyond clinical settings and into everyday life.

While it’s widely recognized that music can evoke emotions—lift our spirits, soothe our nerves, or bring us to tears—recent research from my lab at the University of Bergen in Norway reveals that it can also transform our thought processes. A 2019 study demonstrated that participants who listened to heroic or melancholic music while letting their minds wander experienced significant cognitive effects. The uplifting pieces invigorated participants and inspired positive thoughts, whereas somber music instilled calmness or ambition. This isn’t just a curiosity; it has real implications for mental health.

Research shows our minds wander frequently, with a Harvard University study indicating that we spend nearly half our waking hours in fantasy, often without improving our mood. Why? During these episodes, the brain’s default mode network (DMN) tends to dominate, fostering imagination and memory but also leading us into negative thought spirals—like worries at 3 AM or regrets about missed trains.

Recent brain imaging research indicates that negative daydreaming engages brain pain networks and the DMN, especially in conjunction with sad music. Specific brain areas, including the posterior sulcus, appear to play a crucial role in this connection. Such distressing thoughts activate neural circuits that are also engaged during physical pain.

Fortunately, the DMN has a natural counterpart—a cognitive executive network that facilitates focus and goal-directed behavior. These two systems are inversely correlated; when one is active, the other becomes subdued. Engaging with music can shift us into this more adaptive state, especially when we participate actively—whether by tapping along, matching our breathing to rhythms, or humming. This redirecting of attention helps to break negative thought cycles, providing our minds with a cognitive “reset.”

This approach doesn’t just elevate mood. A 2023 study found that individuals who tapped along to music reported a marked reduction in physical pain in their fingertips compared to those who simply listened. The combination of musical immersion and motor synchronization proved clinically beneficial in alleviating pain.

These insights point to musical engagement as a delightful form of meditation. Evolution may have shaped our brains to seek out music for precisely this reason: to enhance resilience and build social bonds.

I explore these concepts further in my new book, Good Vibrations: Unleashing the Healing Power of Music, which also offers practical techniques—such as music-centered breathing exercises and mood-enhancing playlists—to help regulate emotions, reduce anxiety, and alleviate negative thought patterns.

If music possesses such profound effects, it deserves far more recognition than being relegated to mere lifestyle accessory status. It should be woven into education systems, public health initiatives, and our daily routines. Music therapy must become more accessible, and music education—oftentimes the first to be cut in school budgets—should be viewed as essential for brain health, emotional intelligence, and social wellness.

Music is always within reach. The next time your thoughts begin to spiral or stress begins to encroach, resist the urge to check the news on your phone. Instead, turn to your favorite songs. Your mind—and your community—will be grateful.

Stefan Koelsch is a professor of psychology at the University of Bergen, Norway

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Source: www.newscientist.com

Tesla’s Massive Factory in Germany: Shadows Cast on Local Lives

when Elon Musk encouraged Germans to support the far-right Alternative for Germany (AFD) in last year’s election, Manu Heuer, a resident of the small town where the billionaire established Tesla’s European production center, expressed her concerns.

“How can you engage in business with individuals who endorse right-wing extremism?” she questioned Dietimar Wudike, the Social Democrat leader in Brandenburg, who backed the creation of the Tesla Giga Factory in Grunheide.

Heuer described Woidke’s “unfortunate, yet predictable” response, where he dismissed the claim. “He claimed he didn’t know Musk personally, as if that were a valid excuse,” she noted.




Manu Heuer has sought to question local politicians regarding Elon Musk’s backing of the far-right Alternative for Germany party. Photo: Imago/Alamy

She co-founded Citizens’ Initiatives to develop a vibrant community on a sandy plain southwest of Berlin to oppose plans announced in 2019. At the time, there was significant concern regarding the potential environmental effects of factories on the local pine forests and groundwater.

Recently, it is Musk’s politics that have raised alarms. Not only did he notably endorse far-right European parties, but he also appeared to make a Nazi salute at a rally following Donald Trump’s inauguration.




Elon Musk will inspect the vehicle when production commences at the Tesla facility in Grunheide. Photo: Patrick Pleul/AFP/Getty Images

Meanwhile, Tesla’s sales have declined, particularly in Europe, where new vehicle sales have dropped for the fifth consecutive month, despite overall growth in the electric vehicle market.

Heiko Basin, another member of the civic initiative, expressed a sense of schadenfreude. “We had placed our hopes in this,” the carpenter shared during a recent walk in the shadows of the expansive Grunheide factory.

As sales continue to drop, factories face challenges. Production shifts for the Y model have decreased from 3-2 units per day. IG Metal, which has recruited hundreds of workers despite Tesla’s resistance, urged the company to consider placing employees in “Kurzarbeit.”

Regional media has reported that Tesla is relocating to carriers at a former East German airport, approximately 60 km (37 miles) away.

Musk’s apparent Nazi salute elicited shock and horror in Germany, but it went largely unnoticed in Grunheide until the campaign group projected an image on the facade of the Tesla factory with the Nazi-related word “heil” provocatively placed in front of the Tesla logo.

The outcry from the incident was palpable on the factory floor, as workers told tabloid Berlin Klier. “In Tesla Germany, they tried to maintain distance from (Musk) and remained silent,” one worker noted. Now, they could no longer ignore their ties.

Workers are hard to reach and are often compelled to sign non-disclosure agreements (NDAs). Yet, on Khunnu, a work portal allowing employees to express their thoughts anonymously, a Tesla worker shared:

Almut, a local resident, remarked that politicians tout the benefits Tesla has brought to the area, yet “fail to acknowledge the troubling reality that it subsidizes the wealthiest individual in the world who bears no social responsibility for what occurs here.”

She said locals often joke about what might replace the factory if Tesla were to fail. “Ammunition factories? Prisons? In a way, those seem like decent alternatives,” she quipped. The only positive contribution she could recall from Tesla was the robotic lawnmower it donated to a local soccer club.





While local politicians in Grunheide were keen to highlight the advantages of the factory, some residents voiced concerns about the environmental effects of light pollution and excessive water consumption. Photo: Michele Tantussi/Getty Images

Just two weeks prior to the salute, Musk publicly supported the AFD during an hour-long discussion with co-leader Alice Weidel, touching on topics like Hitler, solar energy, and German bureaucracy. Musk mentioned that Tesla had to submit a staggering 25,000-page form to establish the Grunheide factory. Notably, the AFD has vehemently opposed the Tesla facility, citing concerns over US-led turbo-capitalism and the erosion of workers’ rights. “People need to get behind the AFD,” Musk stated.

For Grunheide residents who oppose Musk, their concerns are compounded by the factory’s impact on rural areas characterized by forests, lakes, and rivers.

New bike lanes and roads necessitate the clearing of large swaths of pine forests, threatening the area’s already precarious drinking water resources and officially declared drought zones.




Tesla Giga Factory with forests in the backdrop. Photo: Sean Gallup/Getty Images

The expansive factory complex, covering 300 hectares (740 acres), is set for expansion by another 100 hectares under a plan submitted by the Mayor of Grunheide, despite a local referendum where 62% of voters voiced opposition.

Supporters highlight the 11,000 jobs created by the factories and the positive impact on the local economy in a region previously governed by the Communist Party. Many young residents look forward to more frequent train services to Berlin, improved supermarket stocks, and the elevation of their hometowns alongside Tesla’s other locations in Shanghai, Nevada, and Austin as examples of “green capitalism.” It is said that an invitation to the “Rave Cave” Technodance Space Mask was sought within the factory complex.

For job openings, the Tesla recruitment page emphasizes that diversity is central to its business model, listing numerous positions available from shift managers to maintenance technicians.

Nevertheless, even among those who have previously expressed enthusiasm for Tesla, sentiments have turned cold. Formerly, a group of local teenagers routinely flew drones over the construction site and proudly shared their videos on YouTube. “Even though I’m no longer anonymous about Tesla/Elon, I’m happy to discuss publicly about them,” one teen texted to the Guardian.

There has been no response from the company regarding interview requests or access to the factory.

Arne Christani, the Mayor of Grunheide and a steadfast Musk supporter, expressed confidence that Tesla will thrive in Grunheide. He mentioned he was unfazed by Musk’s statements or actions. “We must differentiate between what happens in the United States and here in Grunheide,” he stated.

Heuer, living 9 km from the factory, remains hopeful of seeing a starry sky from her garden once again. “Since the factory was built, it’s been challenging due to light pollution from the round-the-clock operation,” she remarked, sharing before and after photos on her phone.

Source: www.theguardian.com

How Climate Change Is Impacting Our Daily Lives Right Now

Climate change is already impacting our lives negatively

Ahmad al-Rubaye/AFP via Getty Images

When considering the dangers posed by climate change, floods and violent storms might come to mind, or even unprecedented heat waves. A study conducted in the latter half of 2024 revealed that most Americans view extreme weather as the chief climate threat. Yet, climate change disrupts daily life in many other persistent ways.

“These events significantly impact people’s lives but often don’t make headlines,” states Jennifer Carman from Yale University.

These more subtle consequences of climate change may seem trivial compared to disasters, like worse allergies or increased commute times, but they collectively signify major shifts, according to Carman. Understanding these issues is crucial for individuals to brace for climate changes affecting their everyday experiences. Remarkably, around half of Americans report feeling the effects of climate change a decade ago—double the number of those who don’t.

“Not everyone is affected by severe events,” Carman remarks. “However, everyone experiences the impacts of daily life consistently.”

Climate change drives up food prices and more

Elevated temperatures associated with climate change inflate prices. In a study by Fridrikik and her team at the European Central Bank, they identified strong correlations between temperature and numerous global price indices. They discovered that higher average temperatures lead to both inflation and extreme weather, particularly in equatorial regions, with impacts persisting year-round.

They projected that by 2035, this would escalate annual price inflation rates by 0.5% to 1.2% for various goods, depending on global greenhouse gas emissions. Agriculture is notably susceptible to weather variations, meaning its price impacts may be about twice as significant. “This unpredictability complicates food production,” Carman notes.

Air conditioning usage is rising and becoming more costly

Increasing temperatures escalate air conditioning expenses. In hotter regions, users will need to operate their air conditioners longer and more frequently. This demand can exceed affordable energy bills.

Individuals in previously temperate areas, such as London or the US’s Pacific Northwest, find themselves needing to install air conditioning for the first time. Globally, soaring cooling expenses negate any reductions in heating costs.

Hot weather disrupts sleep

Even with air conditioning, high nighttime temperatures can hinder sleep quality. Research by Renjie Chen from the University of Hudan, along with colleagues, assessed over 20 million nights of sleep data from hundreds of thousands in China. They found that a 10°C rise in night temperature could raise the likelihood of insufficient sleep by 20%. Under severe emissions scenarios, they estimate that each individual in China might lose about 33 hours of sleep per year by the century’s end.

This isn’t just a localized issue. Research by Kelton Minor from Columbia University showed that elevated nighttime temperatures correlated with reduced sleep across tens of thousands of individuals in 68 countries. Findings suggest higher nighttime temperatures result in decreased sleep—mainly affecting older adults and women in hotter, poorer regions.

Climate change intensifies air pollution

Air pollution poses serious health risks, whether from PM2.5 particles or ozone. Recent research indicates that combining higher temperatures with existing pollutants can exacerbate the harmful effects of air quality, particularly among those who spend extended time outdoors.

It can raise temperatures, leading to increased air pollution by surge electricity demands, often serviced by “peaker plants” designed for peak demand; the worst emitting fossil fuel plants.

Historically, fossil fuel-driven pollution has decreased as power grids have become cleaner, yielding public health benefits. However, as climate change fuels more frequent and severe wildfires, decades of progress may be undone, exposing communities to wildfire smoke. One study forecasts that increased smoke exposure could lead to around 700,000 additional deaths in the U.S. by 2050.

Allergies are worsening with global warming

Increased atmospheric carbon dioxide levels lead to longer warm seasons and higher pollen production, exacerbating allergy symptoms. Many individuals have noticed this trend. According to Carman, annual data shows that 38% of respondents believe their allergy seasons have worsened.

Supporting evidence aligns with anecdotal perceptions; William Andreg from the University of Utah and his team found that the pollen season in North America has lengthened since the 1990s, with overall pollen levels increasing by 21%. The majority of these changes have been attributed to human-induced warming.

Travel delays accumulate, whether long-haul or daily

Climate change is increasingly responsible for weather-related interruptions in transportation systems, leading to billions of wasted hours.

For instance, Valerie Mueller and colleagues from Arizona State University studied the impact of routine coastal flooding on commute times in the eastern U.S. They estimated individuals experience about 23 minutes of delays annually due to these floods, which is double the time recorded 20 years ago. Their analysis revealed these delays stem mainly from rising sea levels rather than extreme storm surges.

While a handful of extra minutes might seem negligible, it accumulates to billions of lost hours overall. Over the coming decades, further sea level rise could escalate delays to hundreds of minutes per person annually.

Weather-induced delays are also increasing in train services and airports. The International Air Transport Association reported that weather-related delays rose from 11% of total delays in 2012 to 30% in 2023. Additionally, even if passengers board their flights, climate change can exacerbate certain turbulence, contributing to rougher flights.

Topics:

  • Climate Change/
  • Air Pollution

Source: www.newscientist.com

The Incredible Impact of Brothers on Our Lives

Joshua Goodman, an associate professor of education and economics at Boston University, observed similarly remarkable outcomes at the university level. He analyzed a dataset of students whose scores were close to the cutoff points for entry into what are referred to as “target colleges.” These candidates are nearly identical, differing by just 10 points or less, highlighting that one student’s score can hinge on minor variations. Generally, those who were just above the threshold gained admittance, while those just below did not. Goodman discovered that younger siblings of successful individuals were significantly more likely to attend equally selective universities compared to older siblings who missed the cutoff by a few points. The younger siblings who managed to enter a prestigious university likely elevated their aspirations, seeing a clear path ahead thanks to their older siblings’ experiences.

Michelle Obama’s university experience mirrors Goodman’s findings, despite his research being conducted decades later. Raised in a working-class neighborhood on Chicago’s south side, Obama’s parents did not initially consider Ivy League schools for her. Her older brother Craig excelled academically and gained the advantage of athletic prowess, earning a spot on the basketball team at Princeton University. In her book, Becoming, Obama reflects on the impact of observing her brother’s journey, stating, “No one in my family had any first-hand experience with university, so there was little discussion or exploration.” She noted that she wanted to emulate her brother’s achievements, which ultimately made Princeton a viable choice for her. Despite a guidance counselor suggesting she “wasn’t Princeton material,” Obama remained undeterred, confident in her abilities and potential.

Research by Zang and Goodman indicates that positive interventions for one child from a low-income family can ripple out to benefit their siblings. This suggests that interventions may yield greater overall impact than previously thought, enhancing not just the individual child’s experience, but potentially altering the life trajectories of their entire family.

Zang’s study revealed that nearly one-third of academic similarities among siblings could be attributed to these spillover effects, rather than shared environments or common genetics. However, these ripple effects can also be detrimental, particularly in disadvantaged families. Children from such backgrounds often face academic challenges due to various obstacles. Zang posits that a child with academic ambitions may experience greater distress if their sibling suffers setbacks, as academic performance is a reliable predictor of future income, which can subsequently lead to diminished earnings across the family.

Both Zang and Goodman emphasize that the spillover effect is most pronounced in underprivileged families, suggesting a need for researchers to recognize that sibling influences function differently based on socioeconomic status. For instance, a 2022 study published in the *Frontiers in Psychology* complicated the well-known assertion that the eldest siblings are the most academically esteemed within families. It found that the oldest children in high-risk families and those with non-native English speaking parents do not perform better on cognitive tests, even if they are more prepared for school at age two. This suggests that these families experience increased interaction with older siblings due to their unique challenges.

Source: www.nytimes.com

The Snake Bit This Man Hundreds of Times—Now His Blood Saves Lives.

Tim Friede has endured hundreds of snake bites. Presently, researchers are analyzing his blood with the aim of developing more effective snake bite treatments.

Friede has a long-standing fascination with reptiles and other venomous creatures. He used to milk scorpions and had a collection of dozens of snakes at his home in Wisconsin.

To protect himself from snake bites and satisfy his “simple curiosity,” he started injecting himself with small doses of snake venom, gradually increasing the amount to build his tolerance before allowing a snake to bite him.

“It was very frightening at first,” Friede said. “But the more you do it, the better you become at handling it, and the more comfortable you get.”

While no healthcare professional would endorse this practice, experts indicate that his approach sheds light on how the body functions. When the immune system encounters snake venom, it produces antibodies that can counteract the venom. If exposed to a small quantity, the body might respond before being overwhelmed, and prior exposure can lead to quicker reactions to larger doses.

For nearly two decades, Friede has endured snake bites and self-injections, yet he still keeps a fridge stocked with venom. In a video on his YouTube channel, he showcases the prominent fang marks on his arms from black mamba, taipan, and water cobra bites.

“I essentially wanted to test the boundaries of life and death as much as possible,” he stated.

In addition, Friede sought to contribute to science. He reached out to numerous scientists, requesting studies on the tolerance he had developed.

According to the World Health Organization, approximately 110,000 people die from snake bites annually. Developing antivenoms is both costly and challenging, often requiring large mammals like horses to produce antibodies through venom injections. These antivenoms tend to be effective against only specific snake species and can cause adverse reactions due to their non-human origin.

Tim Friede stands in a lab in Southern San Francisco, California, utilizing his blood to prepare anti-venom for various snake bites.
Centibacs via AP

Upon learning about Friede, Peter Kwon from Columbia University remarked, “Oh, wow, this is quite extraordinary. He is a uniquely special individual with remarkable antibodies developed over 18 years.”

In a publication in the Journal Cell on Friday, Kwon and collaborators shared insights on what Friede’s unique blood can accomplish. They have identified two antibodies capable of neutralizing venom from multiple snake species, aiming to create a treatment that could eventually provide broad protection.

This study is in its early stages—antivenoms are currently tested only on mice, with years needed before human testing can commence. While their experimental treatments show promise for certain snake categories, including mambas and cobras, they are less effective against vipers.

“Despite the potential, there is still much work to be done,” noted Nicholas Casewell, a snakebite researcher at the Liverpool School of Tropical Medicine, in an email. Casewell was not part of the recent study.

Friede’s journey has not been without challenges. He mentioned that a bad snake bite resulted in part of his finger needing amputation, and some severe cobra bites sent him to the hospital.

Friede is currently working with Centivax, which is developing a treatment, and he is hopeful that his 18-year journey might someday lead to a lifesaving solution for snake bites. However, his advice for those inspired to follow his path is straightforward: “Don’t do this,” he cautioned.

Source: www.nbcnews.com

Optimal AI Implementation Can Enhance Healthcare and Save Lives

Physicians as a whole are a very smart group, but they can be resistant to change. The most famous example is probably the 19th century surgeon who refused to wash his hands when going from the mortuary to the delivery room, spreading undiscovered microorganisms that led to the infant's death. Hungarian doctor Ignaz Semmelweis collected statistics to argue that soap and water can save lives, but was ridiculed and ostracized.

Today, we live in more enlightened times and medical practices are generally supported by evidence, but do we always have the right evidence to make changes? For example, do we always have the right evidence to make changes? There are also indications that bringing it into clinical practice could save lives. As we report in “AI Helps Radiologists Detect Breast Cancer During Physical Exams,” radiologists who choose to use image classification AI to help detect breast cancer are detected one extra case per 1,000 people. Across the health system, the impact can be significant.

Does that mean we should encourage doctors to ditch the scrubs and let the machines do it? Far from it. AI systems with large language models like ChatGPT can pass multiple-choice medical tests, but do poorly at conversational diagnosis (see “AI Chatbot Fails Conversational Diagnosis of Patients”). ). Physicians with a good bedside manner and a listening ear remain essential for now.

We should be bolder when testing medical AI systems in real-world settings

Instead, there are two conclusions that can be drawn from these studies. The first is that we need to be careful in using the general term “artificial intelligence.” Although the two systems we report share underlying neural network technology, image classification is a completely different task than text generation, and the latter risks the AI ​​spitting out plausible but inaccurate results. much higher. In other words, not all AIs are created equal.

The second conclusion is that we need to be more bold in testing medical AI systems in real-world settings, not just in the lab or in simulations. The breast cancer study showed that AI can be a useful tool, giving radiologists control over when to use it. This effort to obtain more evidence could save lives, as it did for Semmelweis, who is now considered a medical hero.

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Source: www.newscientist.com

Is Convenience Making Our Lives More Difficult? The Big Idea Examined in this Book

TThe conveniences of modern life are incredible. Currently, my phone is wirelessly playing some of the greatest hits from the 1700s (like Bach) through a portable speaker. You can easily get a ride, order food to your doorstep, or start chatting on a dating app using the same device. To quote Arthur C. Clarke, for modern humans, this technology is third lawindistinguishable from magic.

It’s understandable that our culture seeks out and celebrates these shortcuts. They eliminate boredom, enhance fun, and save time and effort. However, it’s evident that convenience also has a downside.

Before discussing that, it’s crucial to understand why convenience is so attractive. We often resist doing what’s necessary for progress, whether it’s taxes, a pending report, or training. There’s a sense of inertia behind every well-meaning plan. Why is this resistance and the desire for comfort ingrained in us?

Insights from evolutionary psychology, specifically the concept of “evolutionary mismatch,” can provide clarity. Evolutionary mismatch suggests that we evolved for a hunter-gatherer lifestyle while our environment drastically changed, leaving our instincts out of sync with our surroundings.

Viewing the issue through this evolutionary lens makes sense of our tendency towards lethargy and seeking shortcuts. For early humans, food and energy were scarce and unreliable. Survival meant conserving energy wisely to tackle the challenges they faced.

In today’s world, technology has altered our environment to cater somewhat to our energy-conservation instinct. However, adopting trends that prioritize comfort and convenience may come at a cost. While innovations like washing machines and phones have enriched our lives, excessive convenience may pose challenges rather than easing them.

For instance, the increase in depression and anxiety linked to smartphones and social media is worrying. Also, metabolic issues from sedentary lifestyles and reliance on convenient but low-nutrient foods are on the rise. Loneliness levels have prompted the UK to appoint a ‘Minister for Loneliness’ in 2018, partly due to the technologies fostering such isolation.

Over-reliance on coping mechanisms can exacerbate problems they were meant to solve. Choosing comfort excessively can hinder our ability to face life’s challenges. Some discomfort is vital for our growth and survival, as evidenced by our ancestors’ ability to balance safety and risk intelligently.

Super-convenience has its allure, but it might also deplete us unknowingly, making it harder to achieve true success. Human flourishing hinges not just on survival but on growth, problem-solving, and unity in adversity.

Embracing life’s challenges is essential for personal development. While technology offers convenience, it’s crucial to recognize that overcoming obstacles and discomfort is part of our evolutionary heritage. This lesson is critical for the younger generation.

Dr. Alex Carmi is a psychiatrist, psychotherapist, and speaker. thinking mind Podcast.

Read more

A valid reason for causing bad feelings: Insights from the Frontiers of Evolutionary Psychiatry by Randolph M. Nesse (Penguin, £10.99)

behave: Human Biology at its Best and Worst by Robert Sapolsky (Vintage, £12.99)

anxious generation: How the Great Rewiring of Childhood is Driving an Epidemic of Mental Illness, by Jonathan Haidt (Allen Lane, £25)

Source: www.theguardian.com

Michael Mosley’s innovative methods in science have improved lives and promoted health

My first encounter with Michael Mosley was at the BBC Summer Party. A recent documentary I had presented had just aired on horizon, making me eligible to attend the event. Feeling overwhelmed amongst the many celebrities present, I found solace at the bar, quietly observing the crowd, until Michael approached me.

“Hello, I’m Michael Mosley,” he introduced himself. I was well aware of who he was, and we ended up spending the evening conversing. Although I first worked with Michael at an event, that initial meeting at the party left a lasting impression on me. Despite not knowing me, he warmly welcomed me as a newcomer.

Michael’s extensive career as a producer, presenter, and writer at the BBC spanned over 40 years, establishing a unique style of ‘self-experimenting presenter’ in science presentations. He famously delved into self-experimentation, including infesting himself with tapeworms and popularizing the 5:2 intermittent fasting diet to manage his type 2 diabetes.

While Michael faced criticism for his methods, he aimed to communicate science rather than conduct formal experiments. His talent for simplifying complex concepts and making science accessible led to widespread education among audiences.

Personally, Michael served as a valuable mentor, offering practical advice and sharing techniques for effective communication in broadcasting. His influence extended to shaping my approach to interviews and on-camera presentations, guiding my work in academia and beyond.

In the midst of the COVID-19 pandemic, the importance of clear science communication has been highlighted, emphasizing the impact of effectively disseminating information on health issues. Michael’s contributions in this realm have greatly improved public health outcomes and potentially saved lives.

As a close colleague, respected mentor, and cherished friend, Michael Mosley will be deeply missed.

read more:

Source: www.sciencefocus.com

Research reveals that these specific foods can help individuals in their 70s live longer and healthier lives.

Looking to age gracefully? There’s a plethora of advice out there, but the key seems to lie in maintaining a healthy diet.

A recent study published in Nutrition 2024 revealed that only a small fraction of individuals manage to remain disease-free and in good physical, cognitive, and mental health past the age of 70.

However, there’s hope. The same study indicated that adopting a healthy and balanced diet during midlife can significantly increase your chances of healthy aging.


The study, which spanned over 30 years and analyzed data from over 100,000 individuals, showed that people who maintained a healthy diet from their 40s onwards were much more likely to be in good physical shape at age 70.

According to John Myers, a postdoctoral researcher at the Harvard School of Public Health, “People who followed a healthy diet in midlife, especially one rich in fruits, vegetables, whole grains, and healthy fats, were significantly more likely to experience healthy old age.” This underscores the impact of diet on our health as we age.

To enhance your chances of living a longer and healthier life, experts recommend increasing consumption of fruits, vegetables, whole grains, unsaturated fats, nuts, legumes, and low-fat dairy products. Conversely, it’s wise to limit intake of trans fats, sodium, red meat, and processed meats.

While a healthy diet is typically associated with disease prevention, this study highlights its role in promoting healthy aging. It’s not just about avoiding illness; it’s about maintaining overall vitality as we age.

Researcher Angelie Tessier noted, “Our study suggests dietary recommendations for healthy aging should not only focus on preventing diseases but also on fostering a fulfilling life in later years.”

Participants in the study were mainly above 39 years old without chronic diseases at the onset, and they reported their dietary habits every four years. By 2016, nearly half of the participants had passed away while only a small percentage had reached age 70 or older in good health.

When comparing adherence to healthy eating patterns, the study found that individuals in the top group were significantly more likely to achieve healthy aging than those in the bottom group. The strongest correlation was with the Alternative Healthy Eating Index, which rates your diet based on food consumption frequency.

Even after accounting for factors like physical activity, the link between diet and healthy aging remained robust. Healthy eating habits were associated with better physical health, cognitive function, and mental well-being.

About the Experts

Angelie Tessier, a postdoctoral researcher at the Harvard School of Public Health, has research published in esteemed journals like Nature Communications and PLoS One.

Read more:

Source: www.sciencefocus.com

AI Predicting Mortality Risk Saves Lives in Hospital Trial

Electrocardiogram tests used to train AI to predict risk of fatal heart disease

Gerain0812/Shutterstock

Artificial intelligence systems have proven they can save lives by alerting doctors to test patients whose heart test results show they are at high risk of death. In a randomized clinical trial of approximately 16,000 patients across two hospitals, AI reduced overall deaths in high-risk patients by 31%.

“This is actually quite unusual,” he says Eric Topol Researchers at the Scripps Research Institute Translational Institute in California were not involved in the study. “Any drug, [produce] Mortality is down 31%, and it's even rarer for non-drugs, but that's just monitoring people with AI. ”

Chin Lin Researchers at Taiwan's National Defense Medical Center first trained the AI ​​on more than 450,000 electrocardiogram (ECG) tests that measure the electrical activity of the heart, as well as survival data from ECG subjects. The AI ​​learned to generate a percentile score representing each patient's risk of death, and considered patients at at least the 95th percentile to be at high risk.

The researchers then tested the AI ​​alert system with 39 doctors from two different hospitals. When a nurse uploads a new patient's EKG test to a computer server, an AI system analyzes the results and immediately alerts doctors if the patient is deemed to be at high risk.

In addition to reducing the risk of death from all causes, the AI ​​system reduced deaths in high-risk patients from heart disease by more than 90%.

Lin and his colleagues speculate that AI predictions could help focus attention on groups most at risk. Doctors usually respond to alerts with more diagnostic tests or additional treatments.

The AI ​​alert system is already in use at 14 military hospitals in Taiwan.

“This can be implemented in every hospital in the world, and it shouldn't be expensive,” says Topol. “If it's so effective, it should become the standard of care.”

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Source: www.newscientist.com

Scientists have discovered a squid-like plant that mostly lives underground for the first time

The newly described plant Relictithismia kimotsukiensis is only above ground for a few days a year.

Shuichiro Tagane

This small plant, which feeds mainly on fungi and has no pigments, was named as the first new genus of plant in Japan since 1930.

It was discovered in June 2022 by an amateur botanist in Kyushu’s Kimogen Mountains, but it has taken some time to confirm its uniqueness. So far, researchers have found only five individuals in a single location, and estimate that the total population may reach as few as 50.

This plant grows up to 3 cm in height and 2 cm in width and emerges from the ground in just one week each year. It belongs to a group of plants known as fairy lanterns, which gives it its scientific name. Relictithismia kimotsukiensis.

Unlike most other plants, fairy lanterns do not produce the green pigment chlorophyll needed for photosynthesis. Instead, they get their energy from fungi. “This adaptation gives them an alien-looking appearance when compared to more familiar photosynthetic plants,” he says. Kenji Suetsugu from Kobe University in Japan, and was one of the scientists who described the new species.

“The unique appearance of this new plant species certainly evokes images of squid or extraterrestrial life forms, making it a truly unusual and fascinating addition to the plant world.”

Mr. Suetsugu proposed a Japanese name for this plant. Mujina’s tabletranslated as “raccoon candlestick.”

After Suetsugu first learned about the existence of the plant, it took nearly a year for him to realize that the plant was growing there. It was a moment of “joy and relief,” he says. Because he feared it might take 10 years to collect the specimens he needed to adequately describe it.

He hopes the Japanese government will protect the plant as an endangered species and take steps to protect its population because of its proximity to roads.

“[The discovery] This challenges the notion that new species can only be found in remote or unexplored areas, and suggests that even well-studied areas may hold undiscovered botanical treasures.” says Mr. Suetsugu.

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Source: www.newscientist.com

New Insights from a 45,000-year-old Bone Hole into the Lives of our Earliest Ancestors

In a cave beneath a medieval German castle, researchers have discovered a bone pit that is said to reveal the secrets of early humans.

The remains, buried in layers of soil in a collapsed cave, contained genetic material from cave bears and hyenas, as well as the bones of 13 early humans who died about 45,000 years ago.

The discovery, described in three papers published Thursday in the journals Nature and Nature Ecology & Evolution, suggests that early humans may have traveled further north earlier than scientists realized. It shows that they went on an adventure, they were able to make spear-shaped tools, and then humans were able to make spear-shaped tools. A means to thrive in temperatures much colder than today’s climate.

These discoveries, perhaps made through the development of new DNA techniques, are reshaping the way scientists understand the time when humans and Neanderthals roamed the European continent.

Fragments of human bones excavated from a cave in Ranis, Germany.
From Tim Schuler, Springer Nature

The discovery could bring scientists closer to understanding why Neanderthals ultimately became extinct and what role humans played in their demise.

John Hawkes, a paleoanthropologist at the University of Wisconsin-Madison who studies ancient human relatives but was not involved in the study, said the study shows that as Neanderthals neared their demise, different human cultures He said this helps solidify the theory that these spots were developing.

“These groups are doing research. They’re going to go to new places. They live there for a while. They have different lifestyles,” he said of early humans. “They feel comfortable moving into areas where Neanderthals were.”

These discoveries were only possible because previous researchers left no stone unturned. Archaeologists in the 1920s and 1930s previously excavated the Ilsenhöhle Cave beneath Ranis Castle in the Thuringia region of Germany. The castle was built over the cave long before any excavations took place.

That’s when scientists were unable to drill into critical layers of the cave, which collapsed after hitting rock more than five feet thick.

In 2016, researchers returned with updated drilling techniques and new forms of analysis. About 24 feet below the surface, they discovered a layer containing leaf tips (like the tip of a spear) and human bone fragments.

The discovery of human bone fragments led researchers to dig deep into material excavated nearly 90 years ago, where they discovered additional skeletal fragments.


Source: www.nbcnews.com

Innovate with Azure: 5 ways developers’ lives are made easier with cloud tools

There is an interesting and appropriate “spot the difference” Microsoft Visual Studio An advertisement that used to be published in a computing magazine.

On the left side of the image is the desk of an “unhappy” software developer. It's midnight now. Under the gaze of a single desk lamp, mangled piles of paper litter the scene, and yellow sticky notes dangle from a computer screen.

The right side shows the desk of a “happy” software developer. It's clean and tidy, you have a calendar full of social events, and it's a sunny day outside.

The message was clear. It means that developers will feel less stressed if they use his C++, a popular programming language that allows them to develop software regardless of the platform.

Almost two decades later, technology has advanced, but software developers still face many of the same challenges. How do you handle the entire lifecycle of creating a product for your customers, from designing the software to making sure it works and is secure? , to deployment and maintenance of the finished product?

Scaling up and down is smooth
Cloud platforms greatly simplify developers' lives, from planning, writing, editing, and debugging code to delivering it live to customers, even when they don't know what the final requirements will look like. .

Previously, software companies delivered applications and services to customers and then had to guess how much infrastructure was needed to support product delivery and maintenance.

This problem can be further exacerbated by the fact that customers may be struggling to meet highly fluctuating demand from end users.

Azure's scalable cloud platform solves this problem by hosting your software and automatically scaling it as demand increases or decreases, allowing you to focus on what you do best: software development. .

Consider the following case live tech games (LTG) etc. The company was faced with the challenge of supporting 10,000 users simultaneously playing a live football tournament multiplayer mobile game online, a number he needed to increase to 500,000.

“During the 2022 FIFA World Cup, in partnership with ITV, we ran over 30 live tournament games with thousands of players competing simultaneously, and thanks to Azure, everything went perfectly. ” says the LTG co-founder. Co-CEO Samuel Worsley.

Develop and debug all in one place
Software development is a complex process. Especially when there are many cooks involved and everyone, including the boss, has different ideas about what coding language the software should be written in.

“If you like working in one programming language and your colleague likes working in another, that's not a problem with Visual Studio,” says Microsoft UK Head of Digital and Application Innovation, Data and Artificial Intelligence. Director Denise Dourado said. .

Visual Studio is an integrated development environment that allows developers to write, edit, and debug code in one place instead of moving from tool to tool.

“Without Visual Studio, you end up designing code in one place and having to debug it in another place. It takes time,” says Dourado.

The worst thing for developers, she says, is that when they switch from one tool to another, they worry about what will happen to their code, making the development process take a long time.

Audit software is easy
You've built your software, but now you need to deploy and maintain it, which can be a huge headache.Here is Azure DevOp Services Come in.

Azure DevOps can be used collaboratively by multiple people to track changes made to software source code and release them to customers in a live environment.

In addition, at a time of global economic uncertainty, there is a real need to reduce costs and improve efficiency while providing added value to customers whose businesses are undergoing significant digital transformation.

Mobile phone company Vodafone realized that it had too many computer systems within the company and many different code repositories for all of its software. Some control systems relied on Word documents to manually track source code changes.

“At the time, we could automatically roll back a deployment to see specifically which line of code caused the problem, link to the developer, and see why we did something like that. It took us a long time to be able to do that,” says Ben Connolly. Head of Digital Engineering at Vodafone.

“it has been Revolutionize with the power of Azure DevOps. It's all pipeline now, and it's much more auditable than what we had before. ”

Improved productivity
Artificial intelligence (AI) is also increasingly helping developers solve pain points. GitHub, the world's largest code repository and social software development community, leverages AI in the following ways: GitHub Copilot.

“GitHub Copilot provides enhanced features for developers, including suggesting code improvements, identifying common coding errors, and helping developers understand the codebase faster, especially for developers new to the project. ,” adds Dourado.

According to GitHub, 46% of new code is now written by AI, overall developer productivity has increased by 55%, and 75% of developers on the platform are looking to be more creative with their software development. They report that they are now able to concentrate on specific areas.

Software development has been democratized
Microsoft wants to take things a step further by “democratizing” the IT industry and making it possible for people without a software development background to build software, Dourado said. “We're bringing in users from the business environment and allowing them to build programs without necessarily understanding code,” she added.

for example, Azure cognitive services You can automate document processing, improve customer service, understand the root causes of anomalies, and extract insights from content.

“The world of technology is constantly changing, especially around things like AI, and if you are a developer, it may not be your core skill. We’re trying to make it possible to leverage AI without spending months or years,” says Dourado.

“What's important to me is that I don't have to struggle to learn new technology and have more freedom to be creative and take advantage of the features of the application.”


read more

Source: www.theguardian.com

Research indicates that the canine teeth of marsupial carnivores grow continuously throughout their lives.

New research from the University of Tasmania also confirms important and fundamental morphological differences in Tasmanian devils (Sarcophilus harrisii) compared to most other animals.

Young Tasmanian devil (Sarcophilus harrisii). Image credit: Keres H. / CC BY-SA 4.0.

There has long been interest in comparing the biology of placental and marsupial mammals and how different traits relate to adaptation and converging ecomorphological niches in different regions of the world. I’m here. One interesting feature is the tooth replacement pattern.

“Unlike humans, dogs and many other animals, which have a second set of baby teeth and adult teeth, we now know that the Tasmanian devil only has one tooth that serves them throughout their lives.” said researchers at the University of Tasmania. Professor Mena Jonesstudy author.

“When Tasmanian devil joeys are young, they have very small teeth that fit their small bodies.”

“Tasmanian devils are separated from their mothers when they are just one-third of their adult size, and at this point they must become independent and feed themselves.”

“Instead of spending time erupting into adult teeth like humans, the Tasmanian devil’s teeth simply ‘erupt’ from the jaw and gums, pushing out more and more to fill the Tasmanian devil’s large mouth and head. , they raise animals to hold meat and prey and for protection. ”

“This is a really cool fact about a really cool species, and it points to a completely different evolutionary solution to the formation of teeth in growing animals than we know.”

The same phenomenon is seen in local possums and possums, as well as in some ancient marsupials such as the giant volhyaenids and sabertooths of South America.

“This information will help researchers determine the age of the animals they are studying, including those monitored in the wild for Tasmanian devil facial tumor research,” Professor Jones said.

of study Published in Proceedings of the Royal Society B.

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Mena E. Jones. 2023. Overbudding of teeth in marsupial carnivores: compensation for constraints. Procedure R. Soc. B 290 (2013): 20230644; doi: 10.1098/rspb.2023.0644

Source: www.sci.news