Researchers develop record-breaking, highly intricate bird family tree

The latest genealogy is detailed in two supplementary papers published today. journal Nature And that Proceedings of the National Academy of Sciences, researchers have uncovered patterns in the evolutionary history of birds after the massive mass extinction event that wiped out the dinosaurs 66 million years ago. The authors observed rapid increases in effective population size, replacement rate, and relative brain size in early birds, and found that new adaptive mechanisms that drove bird diversification in the aftermath of this pivotal event. Shined a light. The researchers also took a closer look at one branch of the new family tree and found that flamingos and pigeons are more distantly related than previous genome-wide analyzes had shown.

The latest bird family tree outlining 93 million years of evolutionary relationships among 363 bird species. Image credit: Jon Fjeldså / Josefin Stiller.

“Our goal is to reconstruct the entire evolutionary history of all birds,” said Professor Siavash Milarab, a researcher at the University of California, San Diego.

This work is part of that Bird 10,000 Genomes (B10K) ProjectThis is a multi-institutional effort led by the University of Copenhagen, Zhejiang University, and the University of California, San Diego, with the aim of producing draft genome sequences for approximately 10,500 extant bird species.

At the heart of these studies is a suite of algorithms known as ASTRAL, developed by Professor Miralove and colleagues to infer evolutionary relationships with unprecedented scalability, accuracy, and speed.

By harnessing the power of these algorithms, we integrated genomic data from over 60,000 genomic regions and provided a robust statistical foundation for our analysis.

The researchers then examined the evolutionary history of individual segments across the genome.

From there, they pieced together a mosaic of gene trees and compiled them into a comprehensive species tree.

This meticulous approach has allowed researchers to construct new and improved bird genealogies that depict complex divergence events with remarkable accuracy and detail, even in the face of historical uncertainty. I did.

“We found that our method, which adds tens of thousands of genes to the analysis, is indeed necessary to unravel the evolutionary relationships between bird species,” Professor Miralove said.

“We really need all the genomic data to reconstruct with a high degree of confidence what happened during this period of time, 65 to 67 million years ago.”

The scientists also looked at the impact of different genome sampling methods on the accuracy of the tree.

They showed that to reconstruct this evolutionary history, it is important to combine two strategies: sequence many genes in each species and sequence many species. Ta.

“Because we used both strategies in combination, we were able to test which approach has a stronger impact on phylogenetic reconstructions,” said Professor Josephine Stiller from the University of Copenhagen.

We found that it is more important to sample many gene sequences from each organism than to sample from a wider range of species, but the latter method does not allow us to determine when different groups evolved. It was helpful to know. ”

mira love other. They took a closer look at one branch of the updated bird family tree and found that groups including flamingos and pigeons are more distantly related than previous genome-wide analyzes had shown. We attributed the results to an abnormal region on chromosome 4.Image credits: Ed Braun / Daniel J. Field / Siavash Miarab

With the help of advanced computational techniques, the researchers were also able to shed light on anomalies discovered in previous studies. The theory is that a particular part of a chromosome in the bird's genome remained unchanged and blank for millions of years. Description of expected genetic recombination patterns.

“Ten years ago, we put together a family tree. Neo Avesthe group that includes the vast majority of bird species,” said Professor Edward Brown of the University of Florida.

“Based on the genomes of 48 species, we divided neoabees into two broad categories: pigeons and flamingos in one group, and all the rest in the other.”

“This year, when we repeated the same analysis with 363 species, a different family tree emerged that divided pigeons and flamingos into two distinct groups.”

“Given two mutually exclusive family trees, I looked for an explanation that would allow me to determine which family tree was correct.”

“When we looked at individual genes and which trees they supported, it suddenly dawned on us that all the genes that support old trees were all in one place. That's how it all started. “It was,” he explained.

“When we investigated this site, we realized that it was a place where sexual reproduction had been occurring for millions of years, but it wasn't as mixed.”

“Just like humans, birds combine the genes of their father and mother to create the next generation.”

“But in birds and humans alike, when creating sperm and eggs, we first mix together genes inherited from both parents.”

“This process, called recombination, maximizes the genetic diversity of a species by ensuring that no two siblings are exactly alike.”

The authors found evidence that parts of bird chromosomes suppressed this recombination process for millions of years after the dinosaurs went extinct.

It is unclear whether extinction events and genomic abnormalities are related.

They found that flamingos and pigeons resemble each other in this frozen chunk of DNA.

However, when the complete genomes were considered, it became clear that the two groups were more distantly related.

“What is surprising is that this period of recombination suppression can mislead the analysis,” says Professor Brown.

“And because that can mislead the analysis, it was actually detectable more than 60 million years in the future. That's the cool thing about it.”

“Such mysteries may also be hidden in the genomes of other organisms.”

“We discovered this misleading region of birds because we put a lot of energy into deciphering their genomes.”

“I think there are similar cases in other species that are unknown at this time.”

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J. Stiller other. 2024. The complexity of bird evolution revealed by family-level genomes. Naturein press.

Siavash Milarab other. 2024. Suppressed recombinant regions mislead neoavian phylogenomics. PNAS 121: e2319506121; doi: 10.1073/pnas.2319506121

Source: www.sci.news

Researchers suggest innovative therapy for stomach cancer

Cancer cells grow abnormally and are difficult to control. Scientists call this growth on the lining of the stomach stomach cancer. Gastric cancer is a global health concern in the United States, East Asia, and Eastern Europe. There are usually no symptoms at the time of onset, but it often affects people infected with a bacterial species called Helicobacter pylori.

Researchers have found that diagnosing stomach cancer early is difficult, so many people with stomach cancer die within five years of diagnosis. As cancer grows, it moves from the stomach to other organs, such as the kidneys and liver, through a process called metastasis, which increases the severity even further. This problem raises the need for effective early diagnostic and therapeutic targets to combat gastric cancer before metastasis occurs.

Human cells contain molecules that carry genetic information essential for the development and functioning of organs and body systems. This molecule is DNA and it consists of a sequence of four nucleotide bases: adenine, guanine, cytosine, and thymine.

To carry out its role, DNA undergoes two transformations through biochemical reactions. First, it is transcribed into a slightly similar but less stable molecule. RNAIt is a sequence of nucleotide bases that is almost identical to DNA, except that it has uracil instead of thymine. This RNA serves as a template for protein synthesis, and there are various types. Enzymes then convert some of these RNA molecules into in particular messenger RNA or convert mRNA into protein. Proteins allow organs to grow and function.

Not all RNA molecules become proteins. What does not become protein non-coding RNA or ncRNA. These ncRNAs interact with cells and other molecules to control various processes required to form proteins from DNA for cell growth and survival.

In the past, researchers discovered a type of ncRNA called long ncRNA, which affects the body's immune system's ability to fight cancer cells. However, there are no studies specific to their activity in gastric cancer. Therefore, a group of Chinese biomedical researchers investigated how these ncRNAs influence the development of gastric cancer and how scientists can utilize their ncRNAs to predict the survival of gastric cancer patients.

Researchers found that normal and gastric cancer sample from global cancer database called cancer genome atlas. The normal samples were from patients without gastric cancer and served as the standard or reference point for comparison. Using the R programming language and a software package developed for biological data, they investigated which groups of ncRNAs were expressed at different levels in these patients. They used information from a genome browser called ensemble Identify protein-encoding genes located within and around differentially expressed ncRNA regions.

The researchers found that the expression levels of thousands of ncRNAs were different in gastric cancer compared to normal sample tissue. they again, 15 genes surrounding ncRNA regions that influence gastric cancer progression. They found that about 8 out of 10 ncRNAs were expressed at levels higher than those required in normal cells, and the rest were expressed at lower levels.

Additionally, the researchers investigated the time period during which ncRNAs interact with other ncRNAs and mRNAs to influence tumor growth and patient outcomes. They identified five long ncRNAs that interact with mRNA; microRNA. These long ncRNAs caused abnormal increases and decreases in protein levels within cells, influencing differences in tumor development and progression, as well as patient outcomes. They reported one microRNA that could inhibit tumor growth and serve as a potential target during therapy.

They used a statistical method called , to analyze the proportion of cells that fight infections and harmful substances. immune cellswere investigated in cancer and normal samples to determine how each cell interacts with ncRNAs and influences patient survival. The study highlighted that certain immune cells were higher depending on the age and stage of gastric cancer in the patients whose data were obtained. They confirmed the relationship between immunity and long ncRNA regulatory networks in gastric cancer. They identified certain immune cells whose presence increases a patient's chance of surviving stomach cancer, and those whose presence reduces survival.

With this study, the authors hope to identify new potential targets, namely specific immune cells and ncRNAs, to assess patients' chances of recovery and develop effective treatments for them. concluded that further insight into the biological processes involved in gastric cancer was gained. However, the size of the cancer data is much larger than the regular data used for comparison, which may have influenced the results, the researchers reported. They emphasized the need for further research, especially laboratory analysis, to validate the findings.


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Source: sciworthy.com

Researchers to investigate solar eclipses utilizing aircraft and NASA spacecraft

Millions of people across North America are eagerly awaiting the total solar eclipse on April 8th, which promises to be a spectacular show. This rare event will see the moon completely obscuring the sun, providing a unique opportunity for scientific study.

NASA Deputy Administrator Pam Melroy emphasized the significance of this event, stating that it allows scientists to observe the Earth, moon, and sun in a new light. The agency’s primary focus is on studying the sun’s outer atmosphere, known as the corona, which is usually obscured by the sun’s brightness. During a total solar eclipse, the corona becomes visible as a faint light surrounding a glowing halo.

Researchers are particularly interested in the corona as it plays a crucial role in transferring heat and energy to the solar wind, a stream of charged particles emitted from the sun’s atmosphere. Understanding the corona’s behavior can provide insights into solar phenomena such as solar flares and geomagnetic storms, which can impact Earth’s communications and power systems.

Scientists like solar astrophysicist Amir Caspi are taking advantage of this celestial event to study the sun’s atmosphere in detail. By using specialized instruments aboard aircraft and satellites, researchers hope to solve long-standing mysteries related to the sun’s corona and the solar wind.

The upcoming solar eclipse will also see spacecraft like NASA’s Parker Solar Probe and the European Space Agency’s Solar Orbiter observing the sun from different vantage points. These missions aim to gather valuable data about the sun’s atmosphere and solar wind, providing unprecedented insights into solar activity and its potential effects on Earth.

As the sun approaches the peak of its 11-year cycle, researchers are eager to capture any potential solar eruptions and study their impact on space weather. The data collected during the solar eclipse will contribute to our understanding of solar phenomena and improve our ability to forecast space weather events.

Source: www.nbcnews.com

Researchers Develop Detailed Geological Map of Oxia Plain

Using data from ESA’s ExoMars Trace Gas Orbiter and NASA’s Mars Reconnaissance Orbiter, planetary scientists created a 1:30,000-scale geological map of the Oxian Plain, the landing site for ESA’s ExoMars Rosalind Franklin rover mission. Created.



Faudon other. Created the most detailed geological map of Oxia Planitia, the Mars landing site for ESA’s Rosalind Franklin rover. Image credit: Faudon other., doi: 10.1080/17445647.2024.2302361.

Oxia Planum Located on the northern edge of Arabian Terra, it preserves a record of the diverse geological processes that shaped the region.

It is a transitional region between the cratered Arabian Terra and the young lowland plain of the Chryse Planitia.

“Oxia Planum is located near the Martian equator and contains deposits that are nearly 4 billion years old,” said Open University researcher Peter Faudon and colleagues.

“On a geological scale, this would be the oldest landing site ever visited by a spacecraft on Mars.”

“This region is rich in clay minerals that form due to the presence of water. These rocks are ideal for preserving evidence of the earliest forms of life. This makes it possible to predict that life once existed on Mars. It’s a great place to look for clues as to whether this is the case.”

To map the Oxian Plains, the authors used several instruments, including the Color and Stereo Surface Imaging System (CaSSIS) onboard the ExoMars Trace Gas Orbiter and the HiRISE camera on NASA’s Mars Reconnaissance Orbiter (MRO). We used data from.

This map details 15 rock units classified into 6 groups and 7 textural and surface units.

“This map includes the main types of rock and structures with unique shapes, such as ridges and craters,” the researchers said.

“It also features materials that are placed on top, blown by the wind or blown long distances when a meteorite hits the Earth’s surface, for example.”

The result is the highest-resolution map of the Oxian plains to date at a scale of 1:25000, where 1 centimeter corresponds to 250 meters on the surface of Mars.

Average daily driving time is 25-50 minutes. rosalind franklin rover On the map it is 1-2 mm.

“This map is really interesting because it’s a guide to where the answers are,” Dr. Faudon said.

“This serves as a visual hypothesis for what we currently know about the different rocks at the landing site.”

“With the instruments on board the Rosalind Franklin rover, you can test your knowledge on the fly when the time comes.”

of result Published in map journal.

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peter faudon other. 2024. High-resolution map of the Oxian Plains on Mars. Landing site for the ExoMars Rosalind Franklin rover mission. map journal 20(1); doi: 10.1080/17445647.2024.2302361

Source: www.sci.news

Researchers predict AI’s future will mirror that of Star Trek’s Borg

In a new paper in the journal Nature Machine Intelligence, leading computer scientists from around the world review recent advances in machine learning that are converging towards creating collective machine-learned intelligence. They propose that this convergence of scientific and technological advances will lead to the emergence of new types of AI systems that are scalable, resilient, and sustainable.



Saltoggio other. In other words, we will see the emergence of collective AI, where many artificial intelligence units, each able to continuously acquire new knowledge and skills, form a network and share information with each other.

Loughborough University Dr. Andrea Sortoggio and colleagues recognize striking similarities between collective AI and many science fiction concepts.

One example they give is Borg – a cybernetic life form that appears in the Star Trek universe that operates and shares knowledge through a linked collective consciousness.

However, unlike many science fiction stories, the authors envision that collective AI will bring major positive breakthroughs across a variety of fields.

“Instantaneous knowledge sharing across a collective network of AI units that can continuously learn and adapt to new data enables rapid response to new situations, challenges, and threats,” said Dr. Sortogeo.

“For example, in a cybersecurity environment, when one AI unit identifies a threat, it can quickly share knowledge and prompt a collective response, which helps the human immune system protect the body from external intruders. It’s the same as protecting it.”

“It could also lead to the development of disaster response robots that can quickly adapt to the situation they are dispatched to, and personalized medical agents that combine cutting-edge medical knowledge with patient-specific information to improve health outcomes. Yes, the potential applications are vast and exciting.”

Researchers acknowledge that there are risks associated with collective AI (such as the rapid spread of potentially unethical or illegal knowledge), but that AI units have their own objectives and independence from the collective. The authors emphasize the important safety aspect of their vision: to maintain

“This will enable democracy for AI agents and greatly reduce the risk of AI domination by a few large systems,” said Dr. Sortoggio.

After analyzing recent advances in machine learning, the authors concluded that the future of AI lies in collective intelligence.

The study focuses global efforts on enabling lifelong learning (where AI agents can extend their knowledge throughout their operational life) and developing universal protocols and languages that allow AI systems to share knowledge with each other. It became clear that it was.

This differs from current large-scale AI models such as ChatGPT, which have limited lifelong learning and knowledge sharing capabilities.

Such models are unable to continue learning because they acquire most of their knowledge during energy-intensive training sessions.

“Recent research trends are extending AI models with the ability to continuously adapt once deployed, allowing their knowledge to be reused in other models, and effectively recycling knowledge to increase learning speed and energy.” It’s about optimizing demand,” said Dr. Sortogeo.

“We believe that the currently dominant large-scale, expensive, non-sharable, non-lifetime AI models will be replaced by sustainable, evolving, and shared collections of AI units in the future. I don’t believe I will survive.”

“Thanks to communication and sharing, human knowledge has increased step by step over thousands of years.”

“We believe that similar movements are likely to occur in future societies of AI units that achieve democratic and cooperative collectives.”

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A. Saltoggio other. 2024. Collective AI with lifelong learning and sharing at the edge. nat mach intel 6, 251-264; doi: 10.1038/s42256-024-00800-2

Source: www.sci.news

Researchers unravel the genetic code of the Etruscan shrew

Scientists sequenced and analyzed the genome. Etruscan shrew (Suncus etruscus), with an average weight of about 2 grams, it is one of the world’s smallest mammals. This reference-quality genome is an important resource for studies of mammalian development, metabolism, and body size control.

Etruscan shrew (Suncus etruscus). Image credit: Trebol-a / CC BY-SA 3.0 Certificate.

The Etruscan shrew, also known as the white-toothed pygmy shrew, is recognized as one of the smallest living mammals.

This species weighs 1.2 to 2.7 grams and has a body length of 3.6 to 5.3 cm (1.4 to 2.1 inches), with a very large surface area to volume ratio.

As a result, shrews have very high metabolic rates and must consume approximately 1.5 to 2 times their body weight in food each day.

These unique physiological characteristics make the Etruscan shrew a valuable species to the scientific community, contributing significantly to various research fields such as behavioral science and neuroscience.

“High-quality genome assemblies are essential references to enable accurate high-throughput data analysis,” said computational biologist Dr. Yuri Bukman of the Morgridge Institute.

“This will provide valuable insight into the mechanisms of body size control and metabolic rate and will facilitate comparative biological studies.”

In their research, Dr. Buchmann and his colleagues sequenced and assembled the genome of a male Etruscan shrew using protocols developed by the Vertebrate Genome Project.

“Our new Etruscan shrew genome is the first chromosome-level genome assembly for the order Shrews. lilypotyphra,” they said.

The authors manually inspected the primary assembly and identified 22 chromosomes, including the X and Y sex chromosomes.

They also identified 39,091 genes, 19,819 of which were protein-coding genes.

“We found that the shrew genome has relatively little duplication,” Dr. Buchmann said.

“This result does not necessarily correlate with the smallness of the shrew itself.”

“Although shrews belong to a different mammalian family, some similarly small rodents have a lot of overlapping body segments, and Mus musculus is like the champion in the sense that it has the most overlapping segments. So it’s not a question of size.”

of result It was published in the magazine scientific data.

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YV Buchman other. 2024. Chromosome-level genome assembly of the Etruscan shrew Suncus etruscus. scientific data 11, 176; doi: 10.1038/s41597-024-03011-x

Source: www.sci.news

The blue whale genome is sequenced by researchers

An international team of scientists has created a reference-quality, long-read-based genome assembly. blue whale (glans muscle).

blue whale (glans muscle). Image credit: NOAA.

The blue whale is one of the largest animals to have ever existed, with adults reaching up to 33 meters (110 feet) and weighing up to 150 tons.

Megaanimal genome research is of interest to several subfields of biomedicine.

Understanding the developmental mechanisms that control body size may have applications in regenerative medicine and animal husbandry.

Although large mammals tend to live longer and have orders of magnitude more cells, meaning they divide more, they develop mechanisms that increase their resistance to cancer. I am.This mysterious phenomenon is known as Peto's paradox.

“The genome is the blueprint of an organism,” he said. Dr. Yuri Bukmana computational biologist at the Morgridge Institute.

“You need to know the genome of that species in order to manipulate cell cultures and measure things like gene expression. That allows you to do more research.”

“It is generally understood that larger organisms take longer to develop from fertilized egg to adult than smaller organisms, but we do not yet understand why.”

“From that perspective, just the basic biological knowledge is important: How do you make an animal that big? How do you make it work?”

“The practical application of this knowledge lies in the emerging field of stem cell-based therapy,” he said.

“Healing the injury requires stem cells to differentiate into specialized cell types in the relevant organ or tissue.”

“The rate of this process is controlled by some of the same molecular mechanisms underlying the developmental clock.”

In the study, the authors analyzed segmental duplications, large regions of duplicated sequences that often contain genes, which can provide insight into evolutionary processes when compared to other closely or distantly related species. can.

They found that blue whales have had extensive segmental duplication in the recent past, with more copies than bottlenose dolphins (Tursiops truncatus) and that Vorpoise (Phocoena Cave)the world's smallest Cetacea.

Most of the copies of genes created in this way are probably non-functional or their functions are still unknown, but several known genes were identified.

One encodes a protein called metallothionein, which is known to bind to heavy metals and sequester their toxicity, a mechanism useful for large animals that accumulate heavy metals while living in the ocean. be.

Reference genomes also help preserve species. Blue whales were hunted to near extinction in the first half of the 20th century. It is now protected by international treaties and its population is recovering.

“In the world's oceans, blue whales are basically everywhere except in the high Arctic,” Dr. Buchman said.

“So having a reference genome will allow us to make comparisons and better understand the population structure of different groups of blue whales in different parts of the globe.”

“The blue whale genome is highly heterozygous and there is still a lot of genetic diversity, which has important implications for conservation.”

of result appear in the diary molecular biology and evolution.

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Yuri V. Buchman other. 2024. High-quality blue whale genomes, partial duplications, and historical demography. molecular biology and evolution 41 (3): msae036; doi: 10.1093/molbev/msae036

Source: www.sci.news

Sydney Researchers Lead the Way in Brain Chip Technology Ahead of Elon Musk’s Neuralink Neuroscience

BLaine computer interface technology is at the heart of movies like Ready Player One, The Matrix, and Avatar. But outside of the world of science fiction, BCIs are used on Earth to help paralyzed people communicate, to study dreams, and to control robots.

Billionaire entrepreneur Elon Musk announced in January that his neurotechnology company Neuralink had implanted the first computer chip in a human. In February, he announced that patients can now control a computer mouse with their thoughts.

Neuralink’s purpose is noble. It is about helping people who are unable to communicate or interact with their environment. But details are scant. The project quickly raised alarms about brain privacy, the risk of hacking, and other potential issues.



Dr Steve Kassem, senior research scientist at Neuroscience Research Australia, said the Neuralink news should be taken with a “large pinch of salt”. It’s not the first company to do neural implants, he says. In fact, Australia is a ‘hotspot’ for relevant neurological research.

Does the patient dream of electric sheep?

The University of Technology Sydney project, which has received millions of dollars in funding from the Department of Defense, is now in its third phase to demonstrate how soldiers can use brain signals to control robotic dogs.

“We succeeded [demonstrating] Handa can use his brain to issue commands that direct the dog to reach its destination completely hands-free…so the dog can use its hands for other purposes. ” he says.

Soldiers use assisted reality glasses with special graphene interfaces to issue brain signal commands to send the robot dog to different locations. Lin said he is working on making the technology multi-user, faster and able to control other vehicles such as drones.

Meanwhile, Sydney company Neurode has developed a headset to help people with ADHD by monitoring the brain and sending electronic pulses to help them cope with changes. Another his UTS team is working on it. dream machine, which aims to reconstruct dreams from brain signals. It uses artificial intelligence and brainwave data to generate images from your subconscious mind.

And then there are the implants.

good signal

Synchron started at the University of Melbourne and is now based in New York. it is, Mesh inserted into blood vessels in the brain This allows patients to use the Internet by transmitting signals that operate similar to Bluetooth. People can shop, send emails, and communicate online using technology that controls computers.



Synchron has implanted and monitored mesh in many patients, including one in Australia. Patient P4, who has motor neuron disease, had mesh implanted several years ago.

“I think he’s had over 200 sessions,” says Gil Lind, Sychron’s senior director of advanced technology. “He is still progressing well with his implant treatment and is working very closely with us.

“He was able to use the computer through the system…As the disease progressed, it became very difficult to use the physical buttons.

“This allows for online banking, communication with caregivers, [with] Someone I love. ”

Dr Christina Maher from the University of Sydney’s Brain and Mind Center said Synchron’s technology is “miles ahead” of Elon Musk’s, and is more sophisticated and safer as it does not require open brain surgery. Stated. The researchers have also published more than 25 papers, she said.

“As for Neuralink, we don’t know much about it.

“My understanding is that the top priority for them is to test the effectiveness and safety of surgical robots…so they are focusing more on the robotic side of things, and this is a commercial It makes sense from a perspective.”

Need for regulation

But amidst the hype and promise of neurotechnology, there are concerns about who will have access to the beneficial technologies and how they will be protected.

Maher says it’s important to balance the need for innovation with appropriate regulation while allowing access to those who really need it. She says the “gap between the haves and have-nots” is being discussed not just in Australia but around the world.

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“As brain-computer interfaces become more common, people will be divided into those who can afford them and those who cannot,” she says.

Lind said Synchron is focused on those who have the most to gain, such as quadriplegic patients. “We want to expand it as much as possible. We hope to reach a bigger market and help more people in need,” he says.

A personal and pivotal moment for him, he says, was seeing the faces of the clinicians, team, and family of the first patient who received a successful implant.

At Neuralink, Kasem warns that there are always risks when technology is developed by a company that exists to make a profit. “A cell phone plan for the brain is not what we want,” he says.

“And what if this gets hacked? There’s always a risk when it’s not a closed system.”

But it’s more likely that Neuralink will use people’s data.

“Like every app on your phone or computer, Neuralink monitors everything it can. Everything it can,” Kasem says.

“It will be stored somewhere.”

Protect your brain data

Maher agrees that data is a big issue, saying the risk of hacking remains when devices are connected to the internet. She says much of the social media, biometrics, and other data is already out there, but her brain’s data is different.

“meanwhile [BCI companies] They are subject to the same data privacy laws…The difference in many people’s minds is that brain data is very private and it’s your personal thoughts.

“The big picture here is that once you start recording large amounts of brain data, there are absolutely megatons of data out there,” she says.

Despite privacy concerns, Kasem says interacting with the brain has exciting potential.

“We need to remember how powerful and important the brain is. All you are, all you have been, and all you will ever be is your brain and nothing else.” he says.

Quoting American physicist Emerson Pugh, he says the brain has trillions of neural connections that lead to “infinite opportunities.” hand. ”

Source: www.theguardian.com

Brain researchers discover cold sensors in mice

Neuroscientists at the University of Michigan have identified thermoreceptors that mediate the sensation of cold in somatosensory neurons.

GluK2 KO mice have a defect in cold sensing.Image credit: Kai other10.1038/s41593-024-01585-8.

“The field began elucidating such temperature sensors more than 20 years ago with the discovery of a heat-sensing protein called TRPV1,” said Professor Sean Hsu of the University of Michigan.

“While various studies have discovered proteins that sense hot, warm, and even cold temperatures, we have not identified any proteins that sense temperatures below about 15 degrees Celsius (60 degrees Fahrenheit).”

In 2019, scientists discovered The world's first cold receptor protein Caenorhabditis elegans a millimeter-long nematode species that the lab is studying as a model system for understanding sensory responses.

Because the gene that codes for it is Caenorhabditis elegans This protein is evolutionarily conserved across many species, including mice and humans, and this discovery was a starting point for testing cold sensors in mammals. Glutamate ion channel receptor kainate type subunit 2 (GluK2).

In a new study, Professor Xu and colleagues tested that hypothesis in mice with the deficiency. GluK2 Because of the gene, the GluK2 protein could not be produced.

Through a series of experiments testing animals' behavioral responses to temperature and other mechanical stimuli, they found that mice responded normally to hot, warm, and cold temperatures, but not to harmful cold.

GluK2 is primarily found in neurons in the brain, where it receives chemical signals and facilitates communication between neurons.

However, it is also expressed by sensory neurons in the peripheral nervous system (outside the brain and spinal cord).

“We found that this protein serves a completely different function in the peripheral nervous system, processing temperature cues instead of cold-sensing chemical signals,” said Dr. Bo Duan from the University of Michigan.

of GluK2 This gene has relatives across the evolutionary tree, going back to single-celled bacteria.

“Bacteria don't have brains, so why have they evolved a way to receive chemical signals from other neurons?” Professor Xu said.

“But the need to sense its environment, and perhaps both temperature and chemicals, will be very strong.”

“Thus, I suspect that temperature sensing is an ancient function, at least for some of these glutamate receptors, that was eventually adopted as organisms evolved more complex nervous systems. .”

of result appear in the diary natural neuroscience.

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W. Kai other. The kainate receptor GluK2 mediates cold sensing in mice. nut neurosi, published online on March 11, 2024. doi: 10.1038/s41593-024-01585-8

Source: www.sci.news

Peruvian researchers discover new species of miniature deer

Pudera Carlae is the first deer species to be discovered in the 21st century and the first from the New World in over 60 years. Learn more about it here.

Pudera Carlae. Image credit: Sernanp.

The newly described deer species, Pudera Carlae, belongs to the Neotropical deer family, Odokoileini.

“Some questions regarding the phylogeny and taxonomy of Odocoileini, a group of 18 recognized extant species currently assigned to seven genera, remain unclear,” said Dr. Guillermo Delaire of the University of South Australia and his colleague.

“The few available phylogenetic analyzes indicate that some genera are not monophyletic and that species richness within groups is underestimated.”

“One genus that has both problems is the stocky, short-legged dwarf deer, Pudu

“It has two species, the Northern Pudu (Pudu Mephisto File) from Peru, Ecuador, and Colombia, and the Southern Pudu (Pudupuda) from southern Chile and neighboring Argentina.”

In a new study, the authors found that the Pudu Mephisto File species are actually two different species.

“One is distributed north of the Huancabamba depression from the northernmost part of Peru to the north (Ecuador and Colombia), while the other is endemic in Peru south of the Huancabamba depression and does not have a name yet, so we propose naming it Pudera Carlae

“This is the first extant deer species described in the 21st century and the first discovered in the New World in over 60 years.”

The researchers also found that the Pudupuda type species of Pudu are not related to the two northern Pudu species.

“We revalidate the genus Pudera and assign the latter two species to it.”

The team’s paper was published in the mammal journal this month.

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Javier Barrio et al. Extant deer species first described in the 21st century and their reexamination Pudera (Artiodactyla). mammal journal, published online March 1, 2024. Doi: 10.1093/jmammal/gyae012

Source: www.sci.news

Brain activity during sleep linked to Alzheimer’s disease, say researchers

Alzheimer’s disease is a neurological disease that impairs brain functions such as memory and reasoning, and there is currently no known cure. People with this disease begin with basic forgetfulness, gradually lose control of their motor skills, and eventually become unable to complete normal daily activities.

Scientists have discovered that abnormal proteins that accumulate in and around brain cells are the main cause of Alzheimer’s disease. They also discovered that the disease depends on genetics, aging, and lifestyle choices such as being active and eating a healthy diet. However, it is not known how other disorders, such as sleep disorders, may exacerbate symptoms.

Scientists have hypothesized that brain activity during sleep may be related to Alzheimer’s disease because many important memory-related events occur during sleep. Scientists are therefore hoping to find out whether disruptions in brain function during sleep are related to the development of Alzheimer’s disease.

Researchers at Washington University in St. Louis recently tested whether Alzheimer’s disease is related to electrical activity that occurs in the brain during sleep. Most people experience changes in brain activity early in the night as the body relaxes and goes to sleep. Each of these changes sleep vibration event, lasts about 20-40 minutes. The researchers hypothesized that the interactions of brain circuits during sleep oscillations are different in patients with early Alzheimer’s disease and could be used for diagnostic purposes.

To test their hypothesis, the scientists used a machine that measures electrical activity in the brain. electroencephalograph, or brain waves.They chose 205 political partiesParticipants who have previously completed at least 3 nights of EEG measurements, 1 night of home sleep apnea testing, and clinical dementia testing.Based on dementia testing, most One participant had no cognitive impairment, some participants had very mild cognitive impairment, and one participant had mild cognitive impairment.

The researchers asked participants to wear the EEG as a headband while they slept, allowing them to measure brain waves during the sleep oscillation phenomenon. The three types of sleep oscillatory events they measured during the experiment were: theta burst, sleeping spindleand slow waves.

The researchers explained that theta bursts occur when humans are in light sleep and help process information and form memories. Sleep spindles occur during non-rapid eye movement sleep and are involved in memory consolidation. Slow waves occur during deep sleep, slowing heart and breathing rates, and also play a role in memory development.

The researchers categorized each patient’s individual slow-wave events by how often they coincided with sleep spindles and theta bursts. They classified sleep spindle and slow wave events that occur within 1.5 seconds of each other as coupled events. They also classified theta burst and slow wave events that occurred within 0.5 seconds of each other as coupled events.

The researchers found that people with cognitive impairment had weaker electrical activity during theta bursts and greater differences in brain electrical activity during theta bursts and slow waves. They also found that people with cognitive impairment and other biomarkers of Alzheimer’s disease had fewer slow waves with theta bursts and sleep spindles. The researchers interpreted their results to confirm that disruptions in brain circuits involved in memory function during sleep may be associated with Alzheimer’s disease.

The researchers concluded that the EEG pattern of sleep oscillatory events could be used as a biomarker for Alzheimer’s disease. Researchers suggested that early signs of the neurodegenerative process associated with Alzheimer’s disease could be detected in sleeping patients’ brain waves, even before they develop cognitive symptoms. They also believe that the results may provide an accessible and cost-effective tool for monitoring brain health and early Alzheimer’s disease, allowing for earlier responses and improved patient treatment. suggested something.


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Source: sciworthy.com

Researchers solve the enigma of the brown giant panda

The brown and white giant panda is a mutant with a unique coat color found only in the world. Qinling Mountains Chinese.

Kizai is the only brown panda living in captivity. Image credit: Ailie HM / CC BY-SA 4.0 Certificate.

“Variation in fur color has considerable adaptive and cultural value in mammals,” said study lead author Dengfeng Guan, Ph.D., from the Key Laboratory of Animal Ecology and Conservation Biology, Chinese Academy of Sciences, and colleagues.

“This property is directly determined by the ratio of eumelanin to pheomelanin and the density and distribution of melanosomes within the hair.”

“These factors are under complex control by hundreds of genes that influence different aspects of melanogenesis, including melanocyte proliferation and migration, melanin synthesis, and melanosome biogenesis and translocation.”

Giant panda (Airuropoda melanoruca) is one of the most charismatic flagship breeds, distinguished by its striking black and white coat.

However, the discovery brown panda (Ailuropoda melanoleuca qinlingensis) This photograph, taken in the Qinling Mountains of China's Shaanxi province, challenges the conventional wisdom that color photographs of pandas are never possible.

Recognized as a subspecies of the giant panda, this brown panda is extremely rare and is definitely designated as a national treasure.

Since the first brown panda was discovered in 1985, 11 records have been reported by official news or private communications, seven of which have been confirmed by photographs or physical objects. Three cases were from Buping County, two from Yang County, one from Taibai County, and one from Taibai County. Zhou Zhi.

All brown pandas are found only in the Qinling Mountains, indicating that they are endemic to this region.

“The first recorded brown panda, a female named Dan Dan, was rescued from Foping Nature Reserve to Xi'an Zoo in 1985,” the biologists explained.

“She then mated with the black panda Wang Wang and gave birth to a male black panda named Qing Qing in captivity.”

“Dan Dan passed away in 2000 and Chin Chin also died in 2006, leaving no descendants.”

“In 2009, Qi Zhai, a male brown panda cub, was rescued from Fo Ping Nature Reserve and is currently the only brown panda living in captivity.”

Dr. Guan and co-authors established two family trios related to the brown panda Qi Zai and sequenced their genomes.

They analyzed ecological and genetic data obtained from a long-term study of wild giant pandas in Fo Ping Nature Reserve.

Additionally, we investigated the cellular mechanisms underlying brown fur color based on microscopy and transmission electron microscopy analyses.

They are candidate mutations, viz. base 2 The gene is thought to be the most likely genetic basis for brown pandas.

They verified this deletion through sequencing an additional cohort of 192 black pandas and CRISPR-Cas9 knockout mice.

Their findings will not only provide insight into the genetic basis of coat color variation in brown pandas and wild animals, but will also guide the scientific breeding of rare brown pandas.

“The extremely small number of brown pandas and the nature of the frameshift deletion mutation suggest that this mutation may be a neutral or weakly deleterious mutation,” the authors said.

“Remarkably, the two brown pandas (Qi Zai and Dan Dan) are showing normal growth and reproduction; base 2 The knockout mice were viable, fertile, and had no obvious physical abnormalities, indicating that this mutation had no apparent negative impact on the physical fitness of these mice. ”

“However, other physiological effects of this mutation on brown pandas remain unclear. base 2 It is known to be involved in the Alzheimer's disease pathway. ”

“Given the small population size of Qinling giant pandas, weak deleterious mutations may be corrected by genetic drift effects.”

“Further studies on brown pandas and knockout mouse models will therefore provide valuable insight into the functional consequences of this mutation.”

“For a rare coat color mutant of the giant panda that has great scientific and ornamental value, our findings will provide guidance for the scientific breeding of brown pandas.”

of study Published online this week Proceedings of the National Academy of Sciences.

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Dengfeng Guan other. 2024. Color photography: homozygous 25 bp deletion base 2 Giant pandas can have brown and white coats. PNAS 121 (11): e2317430121; doi: 10.1073/pnas.2317430121

Source: www.sci.news

Plant researchers uncover answers to a 125-million-year-old genetic enigma

researchers Cold Spring Harbor Laboratory We discovered two distantly related model plants. Arabidopsis And tomatoes (Solanum lycopersicum), very different control systems can be used to control the exact same gene. Incredibly, scientists have linked this behavior to extreme genetic modifications that occurred over the course of 125 million years of evolution.

Function of CLV3 in Arabidopsis And in tomato, the cis-regulatory sequences are conserved despite extreme divergence.Image credit: Shiren other., doi: 10.1371/journal.pgen.1011174.

Cold Spring Harbor Laboratory scientist Daniel Siren and his colleagues used genome editing to create more than 70 mutant strains of tomato and Arabidopsis plants.

Due to each mutation, CLV3.

The researchers then analyzed how each mutation affected plant growth and development.

when DNA is stored CLV3 Check-in has mutated too much and the fruit has grown explosively.

CLV3 It helps in the normal development of plants,” Dr. Shiren said.

“If the switch hadn't been turned on at exactly the right time, the plant would have looked completely different.”

“None of the fruits are huge and ideal. You have to balance growth and yield.”

“If you only have two giant tomatoes on a plant, is that as beneficial as a reduced yield?”

“There are no easy solutions. When you try to improve something, you always end up sacrificing something.”

In the case of tomatoes, mutations occur near the beginning, but not at the end. CLV3 Genetics had a dramatic effect on fruit size.

for Arabidopsisthe regions surrounding both parts of the gene had to be destroyed.

This suggests that something happened over the past 125 million years that caused plants to evolve differently. What exactly happened remains a mystery.

“We can't go back to our common ancestors because they no longer exist,” Dr. Siren says.

“So it's hard to say what the original conditions were and how they were mixed together.”

“The simplest explanation is that there is a regulatory element that is conserved to some degree, and that is being changed in a subtle way. That's a little unexpected.”

“What is certain is that gene regulation is not uniform across plant species.”

“Uncovering these genetic differences could help make crop genome engineering more predictable.”

“And that would be a huge win not only for science, but also for farmers and plant breeders around the world.”

of study Published in a magazine PLoS Genetics.

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D.Siren other. 2024. Extreme reorganization of cis-regulatory regions controlling deeply conserved plant stem cell regulators. PLoS Genet 20 (3): e1011174; doi: 10.1371/journal.pgen.1011174

Source: www.sci.news

Researchers successfully decode the genome of the elusive night parrot

CSIRO researchers first genome of night parrot (Pezoporus occidentalis)one of the rarest and most elusive birds in the world.

night parrot (Pezoporus occidentalis). Image credit: Arianna Urso / Western Australian Museum.

The night parrot is a relatively small, short-tailed parrot species endemic to Australia.

This species is also known as the porcupine parrot, nocturnal ground parakeet, midnight parrot, solitaire, spinifex parrot, and nocturnal parakeet. first explained It was published in 1861 by British ornithologist John Gould.

The night parrot is one of the most elusive and mysterious birds in the world, with no confirmed sightings from 1912 to 1979.

They were once widespread in the arid regions of Australia, but their numbers have declined due to environmental changes such as predation by cats and foxes.

It is now known only from localized areas in south-west Queensland and Western Australia.

“Dozens of scientific specimens were collected in the 19th century, with one specimen collected in 1912. A specimen was then discovered in south-west Queensland in 1990,” says the CSIRO Australian National Wildlife Collection. said Dr. Leo Joseph, Director.

“A live bird was reported from the same area in 2013, and a live parrot was finally captured and tagged in 2015.”

“This genome will allow us to explore the genetic basis of why parrots are nocturnal, a trait that is very rare in parrots,” he added.

“We investigate functions such as navigation, sense of smell, beak shape, and suboptimal night vision.”

“Researchers will also be able to perform statistical analysis of this individual's genome to estimate the historical population size of Australia's night parrot.”

“We can now compare this annotated genome with other closely related parrot species, revealing the reasons behind its rarity and limited distribution compared to many closely related species. You can.”

Dr Joseph and his colleagues sequenced the armyworm genome using tissue obtained from specimens found in the Pilbara region.

“Access to high-throughput sequencing technology through CSIRO's Applied Genomics Initiative is accelerating genomics research in Australia,” said Dr Gunjun Pandey, CSIRO Environment Directorate Night Parrot Genomics Project Leader.

“We can now generate very high-quality genomes from very small tissue samples, as small as an ant's head or a single mosquito.”

“This level of quality and detail was not possible even five years ago.”

“Genetic data can be used to maximize diversity in conservation programs, so species are resilient and have the best chance of long-term survival.”

The night parrot genome is an exciting scientific resource for understanding more about this bird, but protecting this species from cats, foxes, fire, and habitat loss is also important for its conservation.

“The night parrot genome will open up many opportunities for further research that will help protect this species,” Dr. Pandey said.

“This will allow scientists to develop a plan to save the night parrot, with the ultimate goal of sequencing and publishing the genome.”

Source: www.sci.news

Researchers find five previously unknown species of eyelash pit vipers in South America

Scientists have identified five mysterious species of the genus Viper Botrykiss They live in the jungles and cloud forests of Colombia and Ecuador.



Botrykis Rahimi. Image credit: Lucas Bustamante.

The eyelash viper is distinguished by a unique feature: a set of huge spine-like scales above the eyes.

These eyelashes give the snake a frightening and ferocious appearance, but the true purpose of this feature is still unknown.

However, what is certain is that certain populations exhibit longer and more stylized eyelashes compared to others.

The changes in the condition of the eyelashes led researchers to hypothesize that an undiscovered species existed.

Eyelash vipers are also famous for another characteristic: they are multicolored. The same patch of rainforest may contain individuals of the turquoise morph, moss morph, or gold morph. They all belong to the same species, even though they have completely different attire.

Alejandro Arteaga, a researcher with the Carmai Foundation and Tropical Helping SA, said: “No two individuals have the same color, even if they belong to the same litter (giving birth to live offspring).”

“Some species have a ‘Christmas’ form, a ghost form, and even a purple form, and different varieties can coexist and even breed with each other.”

“The reasons behind these incredible color changes are still unclear, but it is likely that the pit vipers are able to occupy a wide range of ambush perches, from mossy branches to bright yellow heliconias. is.”



Distribution of palm beetles botry extract schlegeli Species complex including 5 new species.Image credit: Arteaga other., doi: 10.3897/evolsyst.8.114527.

The newly identified species of eyelash viper is Botry extract lasix morum, Botrychus crebai, botry extract kwargi, Botrykis Rahimiand botry extract fusaini.

The first three species are endemic to the eastern Columbia Mountains and live in cloud forests and coffee plantations.

Botrykis Rahimi It stands out because it occurs in the remote and pristine Chocó rainforest on the border of Colombia and Ecuador.

botry extract fusaini It lives in the forests of southwestern Ecuador and northwestern Peru.

“The venom of some (perhaps all) of the new viper species is much less lethal and hemorrhagic than the venom of typical vipers. Central American eyelash viper (botry extract schlegeli)” said Tropical Helping SA and Savia Foundation researcher Lucas Bustamante, who was bitten on the finger. Botrykis Rahimi When the photo was taken during a research expedition in 2013.

“There was intermittent localized pain, dizziness and swelling, but after three doses of antivenom within two hours of the sting, it quickly resolved and no scarring remained.”

“One of the key conclusions of the study is that four species in the group face high risk of extinction,” the researchers said.

“Their geographic range is very limited, and 50% to 80% of their habitat has already been destroyed.”

“Therefore, rapid response measures are urgently needed to save remaining habitat.”

of study It was published in the magazine evolutionary systematics.

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A. Arteaga other. 2024. Systematic revision of Eyelash Palm-Pitviper botry extract schlegeli (Serpentes, Viperidae), 5 new species descriptions and 3 revalidations. evolutionary systematics 8 (1): 15-64; doi: 10.3897/evolsyst.8.114527

Source: www.sci.news

Researchers are uncertain about the origins of life on Earth

If you open your eyes anywhere on Earth, there is life, whether it’s pigeons in the park or invisible microbes covering every surface. However, when the Earth was born 4.5 billion years ago, it was barren. How did the first life originate?

Simply put, I don’t know. Then you’ll be able to reproduce it. Scientists can put the right chemicals into a sealed container under the right conditions, and when they open it, they will find a living organism. No one has ever done this before.

But while we don’t know exactly how life began, there are plenty of clues.

Let’s start with the simplest. What is life made of, and where do its components come from? Living organisms contain thousands of chemicals, including proteins and nucleic acids that carry genetic information. Although these chemicals are complex, we now know that their constituent parts are very easily formed.

The first evidence for this was published in 1953 by a young chemist named Stanley Miller. He filled a glass device with water and his three gases to imitate the oceans and air of the young Earth. Miller heated water and delivered an electric shock to the air to imitate lightning. Within a few days, the setup produced amino acids, which are fragments of proteins.

Since then, scientists have conducted many similar studies. In a study published in September 2020, researchers led by Sara Simcucci, now president of a startup company, Alchemy Co., Ltd.), compiled dozens of experiments. They created a “map” that shows how chemicals change into other substances. He started with just six chemicals used daily, such as water and methane. Creates the tens of thousands of substances found in living things.

The implication is that the young Earth was a biochemical factory. However, having a large amount of these chemicals does not necessarily mean that life will emerge. Just like a pile of bricks automatically becomes a house.

This is where things get tricky. Because we have to think about why something is alive. It boils down to three things. Firstly, the organism often has to maintain itself with an outer layer, and removing that outer layer immediately becomes a problem. Secondly, it must feed itself. This involves complex chemical reactions. And third, life must reproduce itself. In other words, life must have genes that can be inherited.

As we know, life requires proteins. Despite being complex chemicals, they form very easily in nature © Getty Images

Research into the origins of life over the past 50 years has been dominated by attempts to create one of these systems on our own, for example by creating genetic molecules that reproduce by copying themselves. Other bits were supposed to come later.

Personally, I have doubts about this approach. None of the three systems live alone; they need each other. Moreover, if Earth were so good at making all the chemicals for life, all three systems could have formed in the same place at the same time. This may be more likely to occur in confined spaces such as deep-sea hydrothermal vents or terrestrial pools.

We still don’t know exactly how life originated, but what was once a complete mystery is now less inexplicable.

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Source: www.sciencefocus.com

Researchers report a 30% decline in California’s western monarch population last year

SAN FRANCISCO — The number of western monarch butterflies wintering in California declined by 30% last year, likely due to the high humidity, researchers announced Tuesday.

Volunteers visiting sites in California and Arizona around Thanksgiving removed 230,000 butterflies from 330,000 butterflies by 2022, according to the Xerses Society, an environmental nonprofit focused on invertebrate conservation. It is said that more than one fish was caught.

Populations of the orange and black insects have rebounded to hundreds of thousands in recent years. In 2020, the number of butterflies plummeted to just 2,000., the lowest on record. But even though the butterflies have recovered, their numbers are still far below what they were in the 1980s, when monarchs numbered in the millions.

Scientists say butterfly populations are critically low in western states because housing construction and increased use of pesticides and herbicides are destroying milkweed habitat along migratory routes. Says.

Climate change is also one of the main factors in the monarch butterfly's extinction, preventing the butterflies from migrating 3,000 miles (4,828 km) each year to coincide with spring and wildflower blooms.

“Climate change is creating challenges for many wildlife species, and the monarch butterfly is no exception,” said Emma Pelton, monarch butterfly conservation biologist at the Xerces Society. “We know that the severe storms we saw in California last winter, atmospheric rivers flowing back to back, are on some level connected to climate change.”

Western monarch butterflies migrate south from the Pacific Northwest to California each winter, returning to the same places and even the same trees, where they huddle together and stay warm. They breed multiple generations along the route until they arrive in California, usually in early November. When warm weather arrives in March, it spreads east of California.

East of the Rocky Mountains, another population of monarch butterflies migrates from southern Canada and the northeastern United States into central Mexico. Scientists estimate that monarch butterfly populations in the eastern United States have declined by about 80% since the mid-1990s, but the decline in the western United States is even steeper.

Source: www.nbcnews.com

Early Arrival of Humans in China Surprises Researchers by Thousands of Years

The first members of our species to reach China may have entered this region from the north

Esteban de Armas / Alamy

Modern humans lived in what is now China by 45,000 years ago. This discovery means our species arrived in this region thousands of years earlier than commonly thought, probably via a northern route through present-day Siberia and Mongolia.

A team co-led by Francesco d'Errico Researchers from the University of Bordeaux in France reexamined an archaeological site in northern China called Shiyu. Originally, he was excavated in 1963 during the turbulent period of China's Cultural Revolution. “It couldn't have been a better time to find such an important site,” D'Errico says.

Shiyu is an outdoor site located in a river gorge. There, 30 meters deep, sand and other sediments were deposited, which the first excavators divided into four horizontal layers, from the bottom of which the second layer contained human It was found that there was evidence of residence in

Excavators discovered more than 15,000 stone artifacts and thousands of animal bones. There was also part of a hominin skull, which anthropologist Wu Lukang identified as a modern human.homo sapiens).

Some of the artifacts were later transferred to the Institute of Vertebrate Paleontology and Paleoanthropology in Beijing. However, those left behind at the local facility were lost, including the hominin bones. “We own maybe 10 percent of the stone tools,” D'Errico says.

D'Errico and his colleagues re-excavated Shiyu to determine its age. They dated 15 sediment samples using a technique called photostimulated luminescence and carbon-dated 10 animal bones and teeth. The hominid layer is approximately 44,600 years old.

D'Errico believes the excavator was “knowledgeable” and correctly identified the skull.

The Shuyu tribe is probably homo sapienssay Alina Katzenovic from the Institute of Archeology and Ethnology in Novosibirsk, Russia, was not involved in the study.

The new study therefore suggests that modern humans arrived in northern China about 45,000 years ago. This would postpone the arrival of our species to China by about 5,000 years.Derico claims to be the next oldest homo sapiens China's site Tengen Cave 40,000 years ago.

Some researchers argue that our species may have arrived earlier than that, up to 260,000 years ago. However, D'Errico points out that researchers: criticized much of the evidence As for the presence of such early humans in this region.

Humans probably entered Asia from Africa and spread through multiple routes, Katzenovich said. They not only explored the tropical southern regions of Asia, but also headed further north. Katzenovich says there are signs of modern human presence in the area. Obi Rakhmat Cave Uzbekistan 48,800 years ago. Perhaps our species reached Shiyu and then China via this route. north route.

When modern humans reached new areas, they encountered hominids that were already living there, such as Neanderthals and Denisovans further east. Genetic evidence shows that we interbred with them. There may also have been cultural exchanges, and the Shiyu artifacts also include what appear to be more ancient human tools.

There is also evidence of long-distance contact. The Shiyu team identified four fragments of obsidian, a volcanic glass. They were able to track them as far as 800 and 1000 kilometers northeast of Shiyu. D'Errico said it was unlikely that the residents traveled this distance themselves, so they were probably part of the group's network. In line with this, Kazenovich said some of Shiyu's artifacts resemble items found as far east as Korea.

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Source: www.newscientist.com

Researchers Are Investigating the Decline in Sperm Counts Globally

The year was 1974. While newspaper columnists were busy talking about the development of in vitro fertilization and the possibility of “test tube babies,” the surprising discovery about male fertility completely escaped their notice.

Two doctors, Iowa State CM Kinloch Nelson and Raymond Bunge, compared semen samples from that time with historical data. Dramatic changes in a man’s sperm count Over the past 20 years. In 1951, one milliliter of semen contained 107 million sperm. By the 1970s, that number had fallen by more than 50% to just 48 million people. The average volume of semen per ejaculation also decreased.

By the 1990s, the problem began to receive considerable scientific attention, although some researchers remained skeptical. They blamed differences in technology or the fact that most of the research involved men already undergoing treatment for infertility. Those doubts are now diminishing. “There is a tremendous amount of scientific evidence showing this decline,” he says. Albert Salas-Huetos at the University of Rovira y Virgili, Spain.

For researchers like Salas-Huetos, the big question is no longer whether this so-called “Spermageddon” is really happening, but why and what to do about it. Research is beginning to uncover environmental toxins that may be the culprit, as well as other lifestyle factors that contribute to the problem. With a better idea of the prime suspects, we may finally be able to put the brakes on this trend, or even reverse it.

decreased sperm count

around the world 1 in 6 people have problems…

Source: www.newscientist.com

Researchers Develop Large Quantum Vortex to Replicate Black Hole Properties

Researchers created tornado-like vortices in superfluid helium

Yoshigin/Shutterstock

Giant quantum vortices could allow researchers to study black holes. This vortex is a special form of liquid helium vortex that exhibits quantum effects. The result has some properties similar to a black hole and acts as a kind of simulator.

In the region around a black hole, the laws of gravity and quantum mechanics interact, producing effects that cannot be observed elsewhere in the universe. This makes these regions particularly important to study. “There are interesting physics happening around black holes, but many of them are out of our reach,” he says. Silke Weinfurtner at the University of Nottingham, UK. “Thus, we can use these quantum simulators to investigate phenomena that occur around black holes.”

To build the quantum simulator, Weinfurtner and his colleagues used superfluid helium, which flows at a very low viscosity, 500 times lower than water. Because it moves without friction, this form of helium exhibits unusual quantum effects and is known as a quantum fluid. The researchers filled a tank with helium with a rotating propeller at the bottom. As the propeller rotated, a tornado-like vortex was generated in the fluid.

“Similar vortices have been created in physical systems other than superfluid helium, but their strength is generally at least several orders of magnitude weaker,” he says. Patrick Svanchara, is also enrolled at the University of Nottingham and is part of the team. The strength and size of the vortex are critical to producing an interaction significant enough to observe between the vortex and the remaining fluid in the tank.

The vortices in this work were a few millimeters in diameter, much larger than other stable vortices created to date. quantum fluid In the past. In quantum liquids, rotation only occurs in tiny “packets” called quanta, which are essentially tiny vortices, so creating such large vortices is difficult. Many of them tend to become unstable when clustered, but the experimental setup here allows the researchers to combine about 40,000 rotating quanta to form what is called a giant quantum vortex. It's done.

“This is an experimental masterpiece,” he says Jeff Steinhauer He received his PhD from the Technion-Israel Institute of Technology, a pioneer in laboratory simulations of black holes. “They took a very well-established, old, classic technology called superfluid helium and did something really new with it, significantly increasing their technical capabilities compared to what had been done in the past. .”

The researchers observed how small waves in the fluid interacted with vortices. This process mimics the way the universe's cosmic field interacts with a rotating black hole. They discovered hints of a black hole phenomenon called ringdown mode. This phenomenon occurs after two black holes combine and the resulting single black hole is shaken by the residual energy of the combination.

Now that it has been established that this type of vortex exhibits behavior similar to that seen in black holes, researchers plan to use quantum vortices to study more elusive phenomena. “This is an excellent starting point for investigating some black hole physics processes, seeking new insights and potentially discovering hidden treasures along the way,” Weinfurtner says. .

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Source: www.newscientist.com

Researchers unravel enigmatic lunar geological puzzles

New research from the University of Bristol has revealed the origin of titanium-rich basaltic magma on the Moon.



A map of titanium abundance on the moon's surface from NASA's Clementine spacecraft. The red area shows a very high concentration compared to terrestrial rocks. Image credit: Lunar and Planetary Institute.

The presence of surprisingly high concentrations of the element titanium (Ti) on parts of the moon's surface has been known since NASA's Apollo missions back in the 1960s and 1970s. The mission successfully recovered samples of solidified ancient lava from the moon's crust.

Recent maps from orbiting satellites show that these magmas, known as titanium-rich basalts, are widespread on the moon's surface.

Professor Tim Elliott and colleagues at the University of Bristol have used advanced isotopic analysis of lunar samples in a series of high-temperature lava labs to identify key reactions that control the composition of these characteristic magmas.

This reaction occurred about 3.5 billion years ago deep inside the moon, replacing elements of iron in the magma with elements of magnesium in the surrounding rock, changing the chemical and physical properties of the melt.

“The origin of the Moon's volcanic rocks is a fascinating story involving an 'avalanche' of unstable, planetary-scale piles of crystals produced by the cooling of a primordial magma ocean,” Professor Elliott said.

“Central to this epic history is the presence of a type of magma unique to the Moon, which explains how such magma reached the surface to be sampled on space missions. It was a tricky problem to solve. I'm really glad we were able to resolve this dilemma.”

“Until now, models have not been able to reproduce magma compositions that match the essential chemical and physical properties of high-titanium basalts,” said Dr. Martin Claver, a researcher at the Institute of Mineralogy at the University of Münster.

“Explaining that low density made eruptions possible about 3.5 billion years ago has proven particularly difficult.”

“We successfully mimicked high-titanium basalts in a laboratory process using high-temperature experiments,” the researchers said.

“Measurements of the titanium-rich basalts also revealed a unique isotopic composition, a signature of reactions that were reproduced in experiments.”

“Both results clearly demonstrate how melt-solid reactions are essential to understanding the formation of these unique magmas.”

of findings Published in today's diary natural earth science.

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M. Claver other. Titanium-rich basaltic melts exist on the lunar surface, conditioned by reactive flow processes. nut.earth science, published online on January 15, 2024. doi: 10.1038/s41561-023-01362-5

Source: www.sci.news

Researchers find approximately 250,000 undetected nanoplastic particles in each liter of bottled water

The average bottle of water contains nearly 250,000 tiny, invisible particles of nanoplastic that were detected and classified for the first time using a dual-laser microscope.

Scientists have long suspected that there are a lot of these tiny pieces of plastic, but until researchers at Columbia University and Rutgers University made calculations, they had no idea how many or what types they were. Researchers examined five samples of each of three common bottled water brands and found particle levels ranging from 110,000 to 400,000 per liter, with an average of about 240,000, according to Monday’s findings.
Proceedings of the National Academy of Sciences.

These are particles less than 1 micron in size. One inch is 25,400 microns (also called a micrometer because it is one millionth of a meter).
The width of a human hair is approximately 83 microns.

Previous research looked at slightly larger microplastics, ranging from visible 5 millimeters (less than a quarter of an inch) to 1 micron. The study found that about 10 to 100 times more nanoplastics than microplastics were found in bottled water.

Nisin Kian, the study’s lead author and a physical chemist from Colombia, said much of the plastic appears to come from the bottles themselves and the reverse osmosis filters used to keep out other contaminants. She did not reveal her three brands because the researchers need more samples and would like to study more brands before singling out one. Still, she said they were common and she bought them at Walmart.

Researchers still can’t answer the big question: Are these nanoplastic pieces harmful to health?

“That’s under consideration right now. We don’t know if it’s dangerous or how dangerous it is,” said study co-author Phoebe Stapleton, a toxicologist at Rutgers University. “We know they invade tissues (of mammals, including humans)…and current research is investigating what they do inside cells.”

The International Bottled Water Association said in a statement: “Currently, there is a lack of standardized (measurement) methods and no scientific consensus on the potential health effects of nano- and microplastic particles. Reports will only unnecessarily scare consumers.”

The American Chemistry Council, which represents plastics manufacturers, had no immediate comment.

The world is “driving under the weight of plastic pollution, with more than 430 million tonnes of plastic produced annually” and microplastics are being found all over the planet.
world ocean,
food and
drinking water
Some of it comes from clothing and cigarette filters, according to
United Nations Environment Programme. Initiatives towards
global plastic treaty It will continue even after negotiations stalled in November.

All four co-authors interviewed said they had reduced their use of bottled water after conducting the study.

Wei Ming, a Colombian physical chemist who pioneered dual-laser microscopy technology, said he has cut his use of bottled water in half. Stapleton said he is now using more filtered water at his home in New Jersey.

But Bayzan Yan, a co-author of the study and a Colombian environmental chemist who has increased tap water usage, said the introduction of plastic could cause problems with the filters themselves.

“There’s no chance of winning,” Stapleton said.

Naixin Qian, a physical chemist at Columbia University, zooms in on an image of microscopic pieces of plastic that appeared as bright red dots in New York on Monday.
Mary Conlon/Associated Press

Outside experts who praised the study agreed there were general concerns about the dangers of plastic particles, but it was too early to say for sure.

“The dangers of plastic itself are an unanswered question. To me, the additives are the most concerning,” said Jason Somarelli, professor and director of the Comparative Oncology Group at Duke University School of Medicine. . He did not participate in this study. “We and other researchers have shown that these nanoplastics can be taken up into cells, and that nanoplastics have the potential to cause cellular stress and DNA damage, altering metabolism and cell function. We know that it contains all kinds of chemical additives that are harmful.”

Somarelli said his unpublished research found more than 100 “known carcinogenic chemicals in these plastics.”

Zoe Diana, an evolutionary biologist at the University of Toronto, said: “The concern is that small particles are showing up in various organs and can cross membranes that they’re not supposed to cross, such as the blood-brain barrier.'' ” he said.

Diana, who was not involved in the study, said this was an exciting development in the study of plastics in the environment and in the body, thanks to the new tools researchers used.

About 15 years ago, Min invented a dual-laser microscopy technique that identifies specific compounds by their chemical properties and how they resonate when exposed to a laser. Yang and Qian approached him about using the technology to find and identify plastics that are too small for researchers using established methods.

“This study could be an important advance in the detection of nanoplastics,” said Kara Lavender-Law, an oceanographer at the Marine Education Association, adding that other analytical chemists will not be able to replicate the technique and results. He said he would like to see it done.

Dennis Hardesty, an Australian government oceanographer who studies plastic waste, said context was needed. The total weight of the nanoplastics found is “approximately the weight of one penny, which is the volume of two Olympic-sized swimming pools.”

Mr. Hardesty is less concerned about nanoplastics in bottled water than others, saying, “I am privileged to live in an area with access to ‘clean’ tap water, and I don’t have access to drinking water in single-use containers. There’s no need to buy one.”

Yang said other municipalities, including Boston, St. Louis and Los Angeles, are starting to look at how much plastic is in their tap water.
Previous research We’re looking for microplastics, and some early tests show tap water may have less nanoplastics than bottled water.

Despite the unknowns about human health, Yang said he has one recommendation for those concerned. It’s about using reusable bottles instead of single-use plastics.

Source: www.nbcnews.com

Researchers can now estimate your biological age based on a snapshot of your body

It is now possible to measure a person’s biological age, which refers to the wear and tear of the body’s cells, as opposed to the chronological age based on the number of years lived. Chinese scientists have developed a new method to predict biological age using artificial intelligence to analyze 3D images of the face, tongue, and retina.

This approach provides a way to estimate biological age more accurately than previous methods that primarily relied on DNA or blood tests and brain scans. By combining images of the face, tongue, and retina, scientists have created a model that can accurately predict biological age. This allows for easier, more accessible, and less invasive methods to estimate a person’s biological age compared to traditional tests.

Research from China’s Macau University of Science and Technology and Shanghai Jiao Tong University involved testing this model on healthy individuals and those with chronic diseases. The results showed that the biological age of individuals with chronic diseases was significantly higher than their chronological age compared to healthy individuals, indicating the potential impact of chronic diseases on aging.

Furthermore, this new method could also be used to assess the effectiveness of anti-aging treatments, such as diet, exercise, and longevity drugs. Dr. Andrew Steele, a longevity expert, highlighted the potential for using photos to evaluate the efficacy of anti-aging strategies and speed up clinical trials in the future.

About our experts

Dr. Andrew Steele is a scientist, author, and presenter, known for his work in the field of aging. He is the author of Ageless: The new science of growing older without getting older. After earning his doctorate in physics, Steele transitioned into biology, using computers to decipher human DNA at the Francis Crick Institute in London.

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Source: www.sciencefocus.com

Researchers map the genetic code of sea cucumbers residing in hydrothermal vents

Chinese researchers have mapped the entire genome. chiridotaheheva a type of sea cucumber collected at a depth of 2,428 m during a submarine trip to a hydrothermal vent.



Chirodotaheheba In the Gulf of Mexico. Image credit: Aquapix and Expedition to the Deep Slope 2007.

The sea cucumber is echinoderm and as such are related to sea urchins and starfish, a group of animals with a very unusual body design.

They are found on the ocean floor around the world, where they devour detritus and use their tentacles to explore sediments.

Although other high-quality sea cucumber genomes are available, this study provides the first genome of a sea cucumber specimen. chiridotaheheva — collected at a hydrothermal vent.

beginning explained In 2004, chiridotaheheva It is known from the deep waters of the Western Atlantic Ocean, but has an international distribution.

It is one of the few echinoderms. occupy All three types of chemosynthetic ecosystems are included: hydrothermal vents, cold seeps, and organic fallouts. This suggests that this species is well adapted to the reducing environment of the deep sea.

Unlike most species that live in cold or hydrothermal vents; chiridotaheheva It does not host chemosynthetic bacteria.

It obtains nutrients from a variety of sources and extracts organic components from sediment debris, suspended solids, and wood debris when available.

“The organisms found in hydrothermal vents are among the most unique life forms on Earth, having evolved special adaptations to survive and reproduce in these harsh conditions,” said the lead author. Dr. Eugene Pu by Sanya Institute of Deep Sea Science and Technology and colleagues.

“For example, many microorganisms employ special metabolic functions to cope with the abundance of sulfur and iron and to withstand the enormous heat near the vent.”

“In addition to microorganisms, there are also multicellular and higher-order organisms that have adapted to the conditions of hydrothermal vents, such as various types of nematodes, snails, crabs, and shrimp.”

In the study, the authors sequenced the genome of an individual. chiridotaheheva collected from the ocean floor of the Indian Ocean Kairei Bent Field (2,428 meters deep).

“The water around the Kailey vent is particularly rich in dissolved iron, compounded by the harsh conditions of high hydrostatic pressure, darkness, and temperature fluctuations,” the researchers said.

“Initial comparative genomic analyzes showed that several gene families are expanded in this sea cucumber, meaning that this species has a higher repertoire of certain gene sets than closely related species. To do.”

“These expanded and unique genes are involved in DNA repair and iron metabolism, among other processes. It shows for the first time that it is reflected.”

“The genomic data will provide a valuable resource for further research on both sea cucumbers and unique spout animals.”

of result appear in the diary Giga Science.

_____

Y Pooh other. 2023. High-quality chromosome genome assembly of sea cucumber chiridotaheheva and its hydrothermal adaptation. Giga Science, in press. doi: 10.1093/gigascience/giad107

Source: www.sci.news

Researchers have developed the ability to forecast which organs are most likely to fail earliest

New research suggests that scientists may now be able to predict which organs will fail first, providing an opportunity for doctors to target aging organs earlier, before disease symptoms appear.

A study published in Nature found that one in five healthy adults over the age of 50 have at least one aging organ, increasing their risk of developing disease in that organ over the next 15 years. This discovery provides insight into the aging process of the body.

How does aging occur at different rates in the body?

We all have two ages: the chronological age that increases by one each year and the “biological age,” which is more flexible and changes based on health status. By studying biological signs within the body, scientists can determine a person’s biological age.

In a study of 5,678 people, researchers at Stanford Medicine determined the biological age of their organs by analyzing proteins in the blood, revealing that if a person’s organs are older than others of the same age, they are at a higher risk of disease.

Each organ in our body dies at a different rate, with certain proteins in the blood associated with specific organs. Scientists developed a machine learning algorithm using protein combinations to predict a person’s biological age and verified its accuracy on 4,000 people.

The study focused on the biological age of 11 important organs and revealed that people with rapidly aging organs are at a higher risk of disease and mortality. The research team hopes to replicate these findings in a larger group of people to detect which organs are aging at an accelerated rate, allowing for early treatment.

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Source: www.sciencefocus.com

Researchers find easy method to drastically enhance your coffee at home

There are all sorts of fancy tools and expensive equipment that can dramatically improve the taste of your coffee, but now scientists have discovered a new trick that requires just a few drops of water.

When you grind coffee, the process creates friction, which causes some cracks in the beans. This generates electricity that causes the coffee particles to clump and stick to the grinder.

Publish the survey results in a magazine Casea team of researchers reported that coffee beans with higher internal moisture levels generate less static electricity.. This meant less coffee was wasted and a stronger espresso was obtained.

This moisture level is achieved by simply adding a small amount of water to the beans. in front Polishing them.

“Moisture determines the amount of charge formed during grinding, whether it’s residual moisture inside the roasted coffee or external moisture added during grinding,” says the senior author. Dr Christopher Hendona computational materials chemist at Orjon University.

“Water not only reduces static electricity and reduces mess during grinding, but it can also have a significant impact on the strength of the beverage and potentially its ability to obtain a higher concentration of desirable flavor.”

Coffee experts weren’t the only people involved in this study. In a strange turn of events, a volcanologist was brought in to better understand what happens when static electricity is generated when grinding coffee.

“During an eruption, magma breaks up into many small particles that come out of the volcano in a large plume. Throughout the process, those particles rub against each other and become electrically charged until lightning occurs.” he says.volcanologist joshua mendez harperauthor of the paper at Portland State University.

“Simplistically speaking, it’s like grinding coffee, grinding the beans into a fine powder.”

During the course of the study, the research team measured the amount of static electricity generated by grinding a variety of commercially and home-roasted coffee beans. These vary depending on factors such as country of origin, roast color, and moisture content.

Although there was no association between static electricity and the coffee’s country of origin or processing method (natural, washed, decaffeinated), the researchers found a link between static electricity and coffee content, roast color, and particle size. found that there is a correlation between

Less power was produced when the coffee had a higher internal moisture content and when the coffee was ground at a coarser setting. The research team also discovered differences in the static electricity generated between light and dark roasts.

When we compared espresso made with the same coffee beans ground with and without water, we found that grinding with water produced a stronger and longer extraction. Similarly, milling with water improves shot-to-shot consistency, overcoming a hurdle for baristas who want consistent results all day long.

“The main material benefit of adding water during grinding is that there is less agglomeration and the bed can be packed more densely,” says Hendon.

“Espresso is the worst culprit for this problem, but there are also benefits seen in brewing methods where you pour water over the coffee, like on the stovetop. Where you don’t see a benefit are methods like a French press, where you steep the coffee in water. .”

Although the research findings primarily focus on coffee, they have implications for other areas as well.

“It’s kind of the beginning of a joke: a volcanologist and a coffee expert walk into a bar and come out with a paper,” Harper says.

“But I think there are many more opportunities for this kind of collaboration. These investigations could help solve parallel problems in geophysics, such as landslides, volcanic eruptions, and how water infiltrates soil. .”

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Source: www.sciencefocus.com

Researchers identify unique species of seal in the Arctic

This scientific study used satellite transmitters, population counts, and DNA analysis of tissue samples to describe the special Kangi ringed seal in the Ilulissat Icefjord. Here, a satellite transmitter is attached to the seal’s back.Credit: Pinngortitaleriffik – Greenland Institute of Nature Research

Local hunters in the Icefjord near Ilulissat are familiar with a special type of ringed seal known as the Kangia seal. Kangia seals vary in size and appearance, being significantly larger than the common Arctic ringed seal, and with markedly different fur colors and patterns. Recent scientific research has revealed that this distinctive seal has been genetically separated from Arctic seals over a long period of over 100,000 years.

Exploring the natural wonders of the Arctic can be difficult. Extreme weather and vast distances often hinder researchers’ quest to uncover nature’s mysteries.

However, a research project led by Greenlandic and Danish researchers has succeeded in describing a new species of ringed seal that lives in an ice fjord near Ilulissat in West Greenland. A unique natural area on the UNESCO World Heritage List.

The results were recently published in a prestigious scientific journal. molecular ecology.

Kangia ringed seals are larger than the typical Arctic ringed seal, and their fur is a different color and has more distinctive markings.Credit: Pinngortitaleriffik – Greenland Institute of Nature Research

small population

For years, researchers worked with local hunters to trap seals in nets and attach small satellite transmitters to their backs. As the seals flew, satellite transmitters sent messages about the seal’s location.

“We found that the Kangia seals mainly stayed within the ice fjords. We were able to count the seals from the plane, so we estimated that there was only about one seal. There are 3,000 special Kangi ringed seals,” said Akual Rosing Asvid, a senior researcher at the Greenland Institute for Nature Research Pingoltitalerifik and one of the researchers who supported the study. .

Color and pattern of the fur of the Kangia ringed seal (left) and a typical Arctic ringed seal (right).Credit: Pinngortitaleriffik – Greenland Institute of Nature Research

Their small population is very unusual compared to the typical Arctic ringed seal, which is huge and often travels thousands of kilometers around the North Pole in search of food.

isolated for thousands of years

The researchers also took small tissue samples from the captive seals. The samples were sent for genetic analysis to determine the seal’s identity. DNA The results revealed that Kangia ringed seals are genetically distinct from typical Arctic ringed seals.

Kangia ringed seals live in the Ilulissat Icefjord, which is a UNESCO World Heritage Site due to its spectacular and unique nature.Credit: Pinngortitaleriffik – Greenland Institute of Nature Research

However, where and how the Kangia ringed seal became isolated from other Arctic ringed seals and why it acquired new special biological characteristics remains a mystery.

Perhaps other arctic fjords also have special seals

The study highlights that there is still much we don’t know about the biodiversity of the Arctic and its potential to adapt to climate change and human activities.

“There are many other fjords in the Arctic that have not yet been studied in detail, and ringed seals may also carry new genetic mutations in these areas,” said Rune Dietz, professor at Aarhus University’s School of Ecological Sciences. Point out. he participated in the research.

Reference: “Evolutionarily distinct ringed seals of the Ilulissat Icefjord” Aqqalu Rosing-Asvid, Ari Löytynoja, Paolo Momigliano, Rikke Guldborg Hansen, Camilla Hjorth Scharff-Olsen, Mia Valtonen, Juhana Kammonen, Rune Dietz, Frank Farsø Rigét, Steve By H Ferguson, Christian Leidersen, Kit M. Kovacs, David M. Holland, Jukka Jarnvall, Petri Auvinen, Morten Tange Olsen, October 19, 2023. molecular ecology.

DOI: 10.1111/mec.17163

Source: scitechdaily.com