Localized Dust Storms on Mars May Lead to Significant Water Loss, New Study Reveals

Evidence suggests that Mars once hosted significant amounts of water. Past studies indicate that the majority of atmospheric water loss occurs during the Martian southern summer. During this season, warm and dusty conditions allow water vapor to ascend to high altitudes, where it escapes into space without condensing. A groundbreaking study has unveiled a previously unidentified pathway for water loss, observed for the first time in the Martian northern summer. This research highlights how a localized, short-lived sandstorm in Mars Year 37 (August 2023) caused a surge in water vapor.



Close-up color image of a small dust storm on Mars, captured by ESA’s Mars Express’ HRSC instrument in April 2018. Image credit: ESA / DLR / FU Berlin / CC BY-SA 3.0 IGO.

Dr. Adrian Brines, a researcher at the Andalusian Institute of Astronomy and the University of Tokyo, stated, “Our findings reveal the impact of this type of storm on Earth’s climate evolution and open new avenues for understanding how Mars has lost water over time.”

While dust storms have long been recognized as significant contributors to water escape on Mars, previous discussions primarily focused on large-scale dust events occurring on a planetary scale.

In this study, Dr. Brines and colleagues demonstrated that smaller, localized storms can significantly enhance the transport of water vapor to high altitudes, where it is lost to space more readily.

Prior research concentrated on the warm and dynamic summers of the Southern Hemisphere, as this is the primary period for water loss on Mars.

The recent study detected an unusual spike in water vapor in Mars’ middle atmosphere, attributed to a localized dust storm during the northern hemisphere summer of Martian year 37.



Diagram demonstrating the atmospheric response to localized sandstorms in the Northern Hemisphere during summer. High dust concentrations significantly enhance solar radiation absorption, promoting atmospheric warming, especially in the middle atmosphere. This increased circulation enhances the vertical transport of water vapor, facilitating its injection at high altitudes and increasing hydrogen efflux from the exobase. Image credit: Brines et al., doi: 10.1038/s43247-025-03157-5.

This surge in water vapor was unprecedented, reaching levels up to 10 times higher than normal—an occurrence not predicted by existing climate models or observed in previous Martian epochs.

Following this event, the amount of hydrogen in Mars’ exobase—where the atmosphere transitions into space—also rose significantly, increasing by 2.5 times compared to the previous year.

Understanding how much water Mars has lost over time hinges on measuring the hydrogen that escapes into space, as this element is produced when water decomposes in the atmosphere.

Dr. Shohei Aoki, a researcher at the University of Tokyo and Tohoku University, noted, “These results provide a crucial piece to the incomplete puzzle of how Mars has persistently lost water over billions of years, demonstrating that brief but intense episodes can significantly influence the evolution of Mars’ climate.”

Discover more about these findings in the featured study, published this week in Communication: Earth and Environment.

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A. Brines et al. 2026. Unseasonal water escape during summer in Mars’ northern hemisphere caused by localized strong sandstorms. Communication: Earth and Environment 7, 55; doi: 10.1038/s43247-025-03157-5

Source: www.sci.news

Gene-Edited Babies: The Future of Genetics, but Not All CRISPR Startups Will Lead the Way

Babies Crawling in Diapers

Every Baby Has About 100 New Genetic Mutations

Mood board – Mike Watson / Getty Images

Let me share some eye-opening news. Every child embodies genetic experimentation, with nature exhibiting indifference if things don’t go as planned. Our genomes present a complex tapestry shaped by conflicting evolutionary forces, and each of us carries roughly one hundred novel mutations.Each birth introduces a unique mutation into the genetic pool.

Thus, I anticipate that in the future, gene editing of embryos will become commonplace once humanity confronts various daunting challenges, including climate change. There may come a time when natural conception is perceived as reckless.

Reaching that future is no trivial task. However, if you’ve been following the buzz from the tech community this year, it’s no surprise you feel optimistic. By 2025, we discovered at least three startups focused on creating gene-edited babies.

So, is the dawn of CRISPR on the horizon, or could these startups potentially face backlash?

Preventing Genetic Diseases

Among these startups, Manhattan Genomics and Preventive aim not for enhancement but to avert severe genetic disorders. This noble objective is commendable, but it’s important to note that many of these conditions can already be forestalled through existing screening techniques, such as genetic testing of IVF embryos prior to implantation, a process with a high rate of success.

So why pursue the development of gene-edited embryos, a complex and legally challenging endeavor, when IVF screening already provides a viable solution?

Preventive did not respond to inquiries, but a spokesperson from Manhattan Genomics noted that couples undergoing IVF often don’t have enough viable embryos to choose from. By editing disease-carrying embryos instead of discarding them, the likelihood of having a healthy child increases. The company believes that gene editing could enhance the chances for approximately ten embryos affected by Huntington’s disease and thirty-five embryos affected by sickle cell disease annually for couples using IVF.

However, this translates to a very limited number of births. Approximately one-third of IVF embryos lead to viable births, and this percentage may drop further post-editing. Furthermore, significant challenges accompany this approach. Although CRISPR technology has advanced, there’s still a risk of introducing harmful mutations as unintended consequences.

Moreover, the editing process often fails to initiate or can continue even after the embryo has begun dividing. This results in various genetic alterations within the same embryo, a phenomenon known as mosaicism. The illegal CRISPR children from China come to mind, announced in 2018.

Consequently, it becomes uncertain whether the mutation causing the disease was indeed corrected in the edited embryo and whether any harmful mutations emerged as a result.

Doing It Right

Solutions do exist. For instance, some gene-edited animals have been developed by modifying stem cells and then cloning them once the desired alterations have been confirmed. However, I previously explained that cloned animals often exhibit various health issues and unexpected traits, underscoring the necessity for foundational research and rigorous oversight should this approach be pursued for humans.

We have two strong examples of responsibly introducing embryonic gene editing through mitochondrial donation initiatives in the UK and Australia. Mitochondria are cellular energy producers that contain their own small genomes. Mutated mitochondria can lead to severe health issues if passed down to offspring, but this risk can be mitigated by substituting them with healthy donor mitochondria.

A version of mitochondrial technology emerged in private fertility clinics in the US during the 1990s, during which humanity witnessed the first genetically modified human. Initial attempts led to the banning of this technology in the US.

While mitochondrial donation was previously prohibited in the UK, changes in the law came about following advocacy from patient groups, extensive dialogue, and consultation. It now receives approvals on a trial basis as needed.Australia is pursuing a similar path.

What Is the Real Objective?

This is the ideal framework for introducing new reproductive technologies: transparently, legally, and under independent supervision. Yet, at least two startups are reportedly conducting experiments in countries with laxer gene editing laws.

This does not advance science, as trust in the claims made by private companies acting without regulatory oversight diminishes. Conversely, this approach could prompt a backlash, leading to more countries tightening regulations against gene editing.

For these billionaires – with Preventive’s investors including notable figures like OpenAI’s Sam Altman and Coinbase’s Brian Armstrong – if your genuine intention is to combat severe genetic diseases, investing in nonprofit research organizations could yield significantly greater results.

Or is the ultimate aim to engineer your own child instead of assisting other couples in achieving healthy pregnancies? This is clearly the mission of the third startup, Bootstrap Bio.

In next month’s column, we will explore whether gene editing can truly be utilized to enhance our children.

Topics:

Source: www.newscientist.com

Protein Shakes Could Have Surprising Levels of Lead

There’s no denying that protein has become a major industry nowadays. A glance at the aisles of your neighborhood grocery store reveals numerous products highlighting their protein content, whether they originate from natural sources like meat and dairy or from processed items such as breakfast cereals and pasta.

Additionally, protein powders are available for those wishing to enhance their protein intake or source protein from non-animal origins, including fitness enthusiasts and vegans.

However, a concerning new report discloses that some of these powders contain another substance alongside protein: lead. Given this revelation, how concerned should you be about protein powder?

Lead Levels

Consumer Reports, an independent nonprofit organization in the United States that assesses the quality of consumer products, evaluated 23 different protein powder and shake formulations.

Their findings, revealed in October, were alarming. More than two-thirds of the products contained lead levels per serving that exceeded what Consumer Reports’ food safety experts deem safe for daily consumption.

Worryingly, certain products contained amounts that were 10 times the Dietary Intake Restrictions outlined by Consumer Reports.

At first glance, the levels of lead found in items meant for human consumption might appear dangerously high. However, it’s important to remember that Consumer Reports sets a relatively low daily dietary limit of 0.5 micrograms (μg) per day, whereas the U.S. Food and Drug Administration (FDA) has a limit of 12.5 μg per day.

Protein powders are made from proteins sourced from animals like casein and whey derived from milk, or from plant sources like soy, pea, and hemp. Source: Getty

Why is there such a significant difference between these recommendations? “My assumption is that Consumer Reports employs much lower benchmark levels than the FDA to address regulatory gaps,” says Dr. Kathryn Schilling, Assistant Professor of Environmental Health Sciences at Columbia University, USA.

This regulatory gap exists because supplements like protein powders do not fall under the categories of food or drugs in the United States. They are classified as dietary supplements and regulated by different FDA guidelines under the Dietary Supplement Health and Education Act of 1994 (DSHEA).

“There are no federal restrictions on heavy metals in supplements in the United States, and manufacturers aren’t required to demonstrate their products’ safety prior to market entry,” Schilling points out. “Given that research shows there is no safe threshold for lead, Consumer Reports may have established its own targets purely for health protection.”

In the UK and Europe, however, protein powders are considered food rather than dietary supplements, which mandates adherence to standard food safety regulations, including regular contaminant testing. But does this guarantee that UK protein powders are free of lead?

“No,” Schilling asserts. “Even with stricter supervision, trace levels can still emerge.”

The Danger

As Schilling emphasizes, no level of lead is safe. This is echoed by both the World Health Organization (WHO) and environmental health research in which Schilling was involved.

Toxic heavy metal exposure can have severe consequences on vital organs, including the brain, heart, liver, and kidneys; the documented harm is well-established.

For instance, a significant study by a major U.S. company published in The Lancet Public Health tracked blood lead levels in 14,000 adults over a 20-year period. Researchers discovered that individuals with elevated blood lead levels were 37% more likely to die from any cause and 70% more likely to succumb to heart disease compared to those with lower lead levels.

The body retains lead in the calcified tissues of bones and teeth, where it can build up and remain for decades. Source: Getty

Similarly, the WHO estimated in 2019 that excessive lead exposure led to over 300,000 deaths from strokes worldwide. Lead can harm blood vessel linings, resulting in inflammation, plaque accumulation, and high blood pressure. This is why the American Heart Association lists lead as a risk factor for cardiovascular diseases.

One of lead’s most insidious characteristics, apart from the damage it inflicts, is its tendency to persist in the body over extended periods.

“When lead enters the body, it accumulates in bones, teeth, and other tissues,” Schilling explains. “It can remain trapped in the skeleton for 10 to 30 years, gradually re-entering the bloodstream.”

Unfortunately, this coincides with the fact that even minimal lead consumption can result in bodily harm. Even microgram amounts of lead ingested daily are associated with increased risks of heart disease, kidney issues, and high blood pressure.

As noted earlier, the body eliminates lead at a sluggish pace. Therefore, consistent small amounts can accumulate more rapidly than they can be reduced.

Metal Detection

Consumer Reports’ analysis also revealed that the two protein powders containing the highest lead concentrations (up to 6.3 μg and 7.7 μg per serving) were plant-based products.

“There’s a scientific explanation for why some plant-based protein powders exhibited elevated metal levels,” Schilling states.

“Plants like peas, soybeans, and hemp have a tendency to absorb metals from the soil. If lead is present in even small amounts in the soil or irrigation water, the plants will take it up during growth.

“When these plants undergo processing, the metals from the original plants become concentrated in the final protein powder. Thus, the findings by Consumer Reports are plausible. However, their study examined only 23 products, leaving us unaware of the cultivation locations or manufacturing processes of the powders.”

Soy is a vital ingredient in many vegan and vegetarian supplements due to its high protein content. Source: Getty

Humans absorb lead from the environment in a manner similar to plants; unfortunately, industrial lead has been incorporated into paints, fuels, pipes, and other products for decades. Residuals persist and continue to infiltrate our food, water, and air today.

“Lead is persistent in soil, dust, and outdated infrastructure,” Schilling notes. “It can still intrude into our homes, water supplies, and food; its prevalence in the environment makes it nearly impossible to eliminate all exposure.”

In fact, a 2019 FDA study estimated that the average American adult is exposed to as much as 5.3 micrograms of lead daily through dietary sources alone. If you inadvertently include a scoop of high-lead protein powder in this total, you could easily surpass FDA limits without even being aware of it.

Even more troubling, Schilling warns that high lead levels in protein powders have long been recognized in the U.S. “We’ve encountered reports like this repeatedly, and little has changed,” she states. “It’s not merely an issue with a single brand or batch; it represents a systemic contamination and oversight problem.”

So, given all this information, how concerned should you be about lead in your protein shakes and powders?

“Protein powder is just one aspect of the bigger picture,” Schilling concludes. “The essential message is not to panic after just one shake, but to acknowledge that even small amounts of lead from various sources can accumulate, highlighting the necessity for enhanced monitoring to remove lead from the products people regularly use.”

Read More:

Source: www.sciencefocus.com

Lead Exposure Could Have Shaped Human Brain Evolution, Behavior, and Language Development

Several hominid species — Australopithecus africanus, Paranthropus robustus, early homo varieties, Gigantopithecus brachy, Pongo, papio, homo neanderthalensis, and homo sapiens — have undergone significant lead exposure over two million years, as revealed by a new analysis of fossilized teeth collected from Africa, Asia, Oceania, and Europe. This finding challenges the notion that lead exposure is merely a contemporary issue.

Lead exposure affecting modern humans and their ancestors. Image credit: J. Gregory/Mount Sinai Health System.

Professor Renaud Joannes Boyau from Southern Cross University remarked: “Our findings indicate that lead exposure has been integral to human evolution, not just a byproduct of the industrial revolution.”

“This suggests that our ancestors’ brain development was influenced by toxic metals, potentially shaping their social dynamics and cognitive functions over millennia.”

The team analyzed 51 fossil samples globally utilizing a carefully validated laser ablation microspatial sampling technique, encompassing species like Australopithecus africanus, Paranthropus robustus, early homo variants, Gigantopithecus brachy, Pongo, papio, homo neanderthalensis, and homo sapiens.

Signs of transient lead exposure were evident in 73% of the specimens analyzed (compared to 71% in humans). This included findings on Australopithecus, Paranthropus, and homo species.

Some of the earliest geological samples from Gigantopithecus brachy, believed to be around 1.8 million years old from the early Pleistocene and 1 million years old from the mid-Pleistocene, displayed recurrent lead exposure events interspersed with periods of little to no lead uptake.

To further explore the impact of ancient lead exposure on brain development, researchers also conducted laboratory studies.

Australopithecus africanus. Image credit: JM Salas / CC BY-SA 3.0.” width=”580″ height=”627″ srcset=”https://cdn.sci.news/images/2015/01/image_2428-Australopithecus-africanus.jpg 580w, https://cdn.sci.news/images/2015/01/image_2428-Australopithecus-africanus-277×300.jpg 277w” sizes=”(max-width: 580px) 100vw, 580px”/>

Australopithecus africanus. Image credit: JM Salas / CC BY-SA 3.0.

Using human brain organoids (miniature brain models grown in the lab), researchers examined the effects of lead on a crucial developmental gene named NOVA1, recognized for modulating gene expression during neurodevelopment in response to lead exposure.

The modern iteration of NOVA1 has undergone changes distinct from those seen in Neanderthals and other extinct hominins, with the reasons for this evolution remaining unclear until now.

In organoids with ancestral versions of NOVA1, exposure to lead significantly altered neural activity in relation to Fox P2 — a gene involved in the functionality of brain regions critical for language and speech development.

This effect was less pronounced in modern organoids with NOVA1 mutations.

“These findings indicate that our variant of NOVA1 might have conferred a protective advantage against the detrimental neurological effects of lead,” stated Alison Muotri, a professor at the University of California, San Diego.

“This exemplifies how environmental pressures, such as lead toxicity, can drive genetic evolution, enhancing our capacity for survival and verbal communication while also affecting our susceptibility to contemporary lead exposure.”

Gigantopithecus blackii inhabiting the forests of southern China. Image credit: Garcia / Joannes-Boyau, Southern Cross University.” width=”580″ height=”375″ srcset=”https://cdn.sci.news/images/2024/01/image_12599-Gigantopithecus-blacki.jpg 580w, https://cdn.sci.news/images/2024/01/image_12599-Gigantopithecus-blacki-300×194.jpg 300w, https://cdn.sci.news/images/2024/01/image_12599-Gigantopithecus-blacki-84×55.jpg 84w” sizes=”(max-width: 580px) 100vw, 580px”/>

An artistic rendition of a Gigantopithecus brachy herd in the forests of southern China. Image credit: Garcia / Joannes-Boyau, Southern Cross University.

Genetic and proteomic analyses in this study revealed that lead exposure in archaic variant organoids disrupts pathways vital for neurodevelopment, social behavior, and communication.

Alterations in Fox P2 activity indicate a possible correlation between ancient lead exposure and the advanced language abilities found in modern humans.

“This research highlights the role environmental exposures have played in human evolution,” stated Professor Manish Arora from the Icahn School of Medicine at Mount Sinai.

“The insight that exposure to toxic substances may conjure survival advantages in the context of interspecific competition introduces a fresh perspective in environmental medicine, prompting investigations into the evolutionary origins of disorders linked to such exposures.”

For more information, refer to the study published in the journal Science Advances.

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Renaud Joannes Boyau et al. 2025. Effects of intermittent lead exposure on hominid brain evolution. Science Advances 11(42); doi: 10.1126/sciadv.adr1524

Source: www.sci.news

Ancient Lead Exposure Could Have Shaped Brain Evolution

Homo sapiens may have developed greater tolerance to lead exposure compared to other hominids

frantic00/Shutterstock

Research on fossilized teeth indicates that ancient humans were exposed to harmful lead for over two million years, suggesting that modern humans might have adapted to handle this toxic metal more effectively than their predecessors.

Traditionally, lead poisoning was associated with modern issues such as industrialization, poor mining techniques, and lead additives in fuels. Fortunately, efforts to phase out lead exposure have been underway since the 1980s.

This toxin is particularly harmful to children, hindering physical and cognitive growth, while adults may experience a range of serious physical and mental health issues.

Dr. Renaud Joanne Bois and colleagues from Southern Cross University in Lismore, Australia, aimed to investigate whether our ancient ancestors faced similar lead exposure.

They examined 51 fossilized hominin teeth, representing species such as Australopithecus africanus, Paranthropus robustus, Gigantopithecus black, Homo neanderthalensis, and Homo sapiens. The fossils were sourced from regions including Australia, Southeast Asia, China, South Africa, and France.

The research team utilized laser ablation techniques to identify lead concentrations in the teeth, revealing layers of lead that accumulated during the growth of these hominids. This exposure could be attributed to environmental contaminants, such as polluted water, soil, or volcanic eruptions.

Dr. Joanne Boyau noted the surprising levels of lead discovered within the teeth. For instance, Gigantopithecus, a massive ancestral relative of today’s orangutans, primarily lived in what is now China. “If current humans exhibit similar lead levels, it indicates considerable exposure from industrial activities,” she remarked.

The research then shifted focus to understanding how both modern humans and Neanderthals managed lead exposure. The team created lab-grown brain models called organoids to analyze differences in the NOVA1 gene in both species, subsequently assessing the effects of lead neurotoxicity on these organoids.

“Our findings indicate that modern NOVA1 is significantly less impacted by lead neurotoxicity,” states Joannes Boyau.

Crucially, when archaic organoids expressed NOVA1 under lead exposure, another gene, Fox P2 exhibited notable differences.

“These genes are linked to cognitive functions, language, and social bonding,” explains Joannes-Boyau. “The diminished neurotoxicity in modern humans compared to Neanderthals could provide a crucial evolutionary advantage.” This suggests that lead exposure has influenced our evolutionary history.

However, Dr. Tanya Smith from Griffith University in Brisbane, Australia, remains cautious about the conclusions drawn by the researchers regarding lead exposure levels or potential evolutionary benefits inferred from their organoid studies.

“This paper is complex and makes speculative claims,” Smith emphasizes. “While it seems logical that ancient humans and wild primates faced some level of lead exposure, the limited scope and variety of fossils studied do not necessarily demonstrate that our ancestors were consistently exposed to lead over two million years.”

Exploring Neanderthals and Ancient Humans in France

Join New Scientist’s Kate Douglas on an engaging exploration of significant Neanderthal and Upper Paleolithic sites across southern France, spanning from Bordeaux to Montpellier.

Topic:

  • Human Evolution/
  • Ancient Humans

Source: www.newscientist.com

We’ve Adapted to Local Micronutrient Levels, but This Could Lead to Issues

Numerous Mayan individuals reside in Acanceh, Mexico

Educational Images/Universal Image Groups via Getty Images

Historically, the quantity of zinc and other trace elements in human nutrition was largely influenced by the local soil conditions. Recent findings suggest that our ancestors adapted to varying levels of micronutrients as they dispersed globally.

This adaptation may have resulted in notable repercussions. For instance, the shorter statures observed in certain populations might be a consequence of adapting to low iodine availability. Additionally, these historical adjustments may lead to some individuals today experiencing deficiencies or excesses of specific micronutrients.

“For much of human history, the micronutrient profile of our diet has been determined by the soil beneath us,” stated Jasmine Reese from the University of Pennsylvania.

Reese and her team analyzed the genomes of nearly 900 individuals globally to uncover evidence of adaptation to local concentrations of 13 trace elements, including iron, manganese, and selenium. They investigated signs of positive selection in 270 genes related to the ingestion of these elements, highlighting benefits of genetic variations that became more common within certain populations.

The most compelling evidence was for iodine-related genes in the Maya populations of Central America. A similar pattern was observed in the Mbuti and Biaka peoples of Central Africa.

In 2009, it was suggested that the short stature of the Mbuti and Biaka peoples may be attributed to their adaptation to low iodine levels. This relates to iodine-binding genes that influence thyroid hormone function and subsequently growth. These groups are also notably more susceptible to thyroid enlargement due to dietary iodine deficiencies compared to nearby populations.

Maya individuals also exhibit notably shorter statures, providing supporting evidence for the hypothesis that adaptations to low iodine levels influence height. Moreover, it is emphasized that the soils in the Mayan regions, particularly rainforests, are recognized as low in iodine.

“This is quite speculative,” she notes. “While I can’t definitively link short stature directly to iodine levels, we observe a striking correlation with the selection of iodine-related genes in these shorter populations.”

In the Uighur and Blahui populations of Central and South Asia, where soil magnesium concentrations are particularly elevated, there is strong selection impacting two genes involved in magnesium uptake. Some gene variants correlated with low magnesium levels suggest adaptive changes that minimize magnesium absorption to avoid toxicity from environmental excess.

These instances are merely a couple of examples. The research team has identified signs of positive selection related to at least one micronutrient across virtually all examined populations worldwide. “We truly observe a widespread signature of adaptation,” Reese states.

This research marks just the beginning, she emphasizes. Further investigations are crucial to elucidate the impacts of the numerous genetic variants discovered by the team. Given the global trade in food, individuals within certain populations may require increased or decreased intake of specific micronutrients. Reese compares this to populations in the UK, where individuals with darker skin may need vitamin D supplementation not just in winter but throughout the entire year.

“Understanding whether a specific population may require certain micronutrient supplements is essential,” notes Mark Stoneking at the Max Planck Institute for Evolutionary Anthropology in Germany.

“They’ve conducted groundbreaking work in identifying signatures of selection from genomic data,” he states. “However, further research is needed to confirm these findings as genuine cases of selection, as some may inevitably turn out to be false positives.”

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Source: www.newscientist.com

Research Suggests Future Ozone Changes May Lead to Unexpected Global Warming

The prohibition of ozone-depleting substances like CFCs has facilitated the recovery of the ozone layer. However, when paired with rising air pollution levels, the heating effects of ozone are now expected to warm the planet by an additional 40% more than previously estimated.

Antarctica’s ozone hole in 2020. Image credit: ESA.

“CFCs and HCFCs are greenhouse gases contributing to global warming,” stated Professor Bill Collins of Reading University and his colleagues.

“Countries have banned these substances to protect the ozone layer, with hopes it will also mitigate climate change.”

“However, as the ozone layer continues to heal, the resulting warming could offset much of the climate benefits we expect from eliminating CFCs and HCFCs.”

“Efforts to reduce air pollution will limit ground-level ozone.”

“Still, the ozone layer will take decades to fully recover, irrespective of air quality policies, leading to unavoidable warming.”

“Safeguarding the ozone layer is vital for human health and skin cancer prevention.”

“It shields the Earth from harmful UV radiation that can affect humans, animals, and plants.”

“Yet, this study indicates that climate policies must be revised to consider the enhanced warming effects of ozone.”

The researchers utilized computer models to project atmospheric changes by the mid-century.

The models continued under a scenario of low pollution, where CFCs and HCFCs have been eliminated as per the Montreal Protocol (1987).

The results indicate that stopping the production of CFCs and HCFCs—primarily to defend the ozone layer—offers fewer climate advantages than previously thought.

Between 2015 and 2050, ozone is predicted to cause an excess warming of 0.27 watts per square meter (WM-2).

This value denotes the additional energy trapped per square meter of the Earth’s surface—carbon dioxide (which contributes 1.75 WM-2) will rank as the second-largest influence on future warming by 2050.

“Countries are making the right choice by continuing to ban CFCs and HCFCs that endanger the ozone layer globally,” stated Professor Collins.

“While this contributes to the restoration of the ozone layer, we’ve discovered that this recovery results in greater planetary warming than initially anticipated.”

“Ground-level ozone generated from vehicle emissions, industrial activities, and power plants also poses health risks and exacerbates global warming.”

The results were published in the journal Atmospheric Chemistry and Physics.

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WJ Collins et al. 2025. Climate forcing due to future ozone changes: Intercomparison of metrics and methods. Atmos. Chemistry. Phys 25, 9031-9060; doi: 10.5194/ACP-25-9031-2025

Source: www.sci.news

Innovative Perspectives on Brain Health Could Lead to Essential New Treatments

Sumaid Pal Singh Bakshi/Unsplash

Healthcare has witnessed remarkable advancements over the past few decades. In high-income nations, the survival rate for certain types of pediatric leukemia has increased from about 10% to over 90%. HPV vaccinations have decreased the incidence of cervical cancer, and early detection of HIV can lead to life expectancies similar to that of the general population.

In contrast, progress in mental health treatment has been less pronounced. Psychiatry often struggles with a perception of stagnation in treatment methodologies. Historically, it has heavily relied on psychopharmaceuticals developed in the mid-20th century. The field has remained largely anchored to these early drug treatments.

This stagnation is not due to a lack of effort. In the 1970s, molecular psychiatry emerged, focusing on the molecular basis of mental health conditions through proteins, genes, and signaling pathways. The goal was to anchor diagnostics and treatments to biological mechanisms instead of merely interpreting subjective symptoms. Despite advances in genetic research, including exploring the genetic links to schizophrenia, we have yet to see significant improvements in mental health treatment paralleling those in physical health.

The new approach is targeting chronic inflammation.

Given that approximately 8-16% of individuals in high-income countries like England experience anxiety and depression, a fresh perspective is crucial. Current innovative approaches focus on chronic inflammation, a phenomenon linked not just to heart disease and type 2 diabetes, but also to mental health.

For many, chronic low-grade inflammation results from the pace of modern life, often fueled by factors such as stress, obesity, and poor dietary choices. Promising developments suggest that certain anti-inflammatory medications may have potential benefits for the brain, alleviating issues associated with depression and dementia (“Chronic inflammation harms your mind. Here’s how to calm it down”).

These findings also clarify that managing mental health can be approached through actions such as regular exercise, relaxation techniques, and nutritious eating.

While this path may not work for everyone, given that antidepressants fail to help approximately 30% of those treated for depression, any progress is welcomed.

Topics:

Source: www.newscientist.com

How Hot Spring Rocks Could Lead to Discovering Life on Mars – Demon

What if the secrets to discovering life on Mars lie hidden in our own environment? In the planet’s most extreme habitats, microbial life flourishes in unlikely places—from icy tundras to searing, acidic springs. These unique ecosystems not only support life but also preserve evidence of it. Among these, hot springs are particularly notable for generating distinctive silica-rich formations.Silica Center is capable of trapping remnants of ancient microbes.

Silica occurs when silica-laden water from hot springs rises, cools, and evaporates, leaving behind hardened silica that can encapsulate microorganisms, thus fossilizing them. NASA’s Spirit Rover discovered similar silica sinter in Gusev Crater on Mars, raising questions about whether these ancient Martian hot springs may also preserve signs of past life.

An international research team has revealed that fat-like molecules from cells, lipids, can endure alongside these silica sinters and might be detected using equipment akin to that on Martian rovers. These lipids can persist for millions of years and serve as chemical fossils, or biomarkers in the fossil record. They provide insights into the types of life that once existed in these environments, aiding scientists in reconstructing ancient ecosystems.

Researchers collected silica sintered samples from six hot springs in New Zealand’s Taupo volcanic region, where the waters range from 77°F to 203°F (25°C to 95°C) and vary in acidity. First, they extracted the lipids from the sintered material chemically. Next, they characterized these lipids using instruments that fragment the molecules into smaller components, identifying them by mass.Gas chromatography-mass spectrometry (GC-MS) was utilized.

The team employed GC-MS to identify a broad array of lipid molecules, including fatty acids, alcohols, sterols, and n-alkanes from the sinter. Most of these molecules likely originated from bacteria that either use sunlight or sulfate as an energy source, and such microorganisms are well-suited for extreme environments. Some lipids identified also stemmed from other sources, like algae and plants. The researchers interpreted this diversity of lipids as indicative of both ancient and contemporary microorganisms. They referred to the old fossilized communities preserved with newer ones in the silica, noting the mix of heat-altered and fresh compounds.

The shape and texture of sintered rocks were also found to influence the preservation of lipid biomarkers. A fine, pointed texture known as spicular sinter retained more lipids compared to knobbed or crusty types. These thorny textures form at the edges of hot spring pools where microorganisms interact with rapidly cooled silica-rich water, creating delicate silica structures that grow like small fingers. Researchers suggested that these fine textures offer protection to microorganisms against erosion and radiation. They believe these finger-like silica formations are particularly promising for detecting traces of past life on Mars, similar to those seen by the Spirit Rover.

To evaluate whether current Rover instruments could detect ancient lipids, researchers analyzed two silica sintered samples using techniques similar to those used by rovers.NASA’s Curiosity Rover employs a method called Pyrolysis-GC-MS, which does not require prior chemical extraction of lipids. The entire sample is heated until the molecules transform into gas, which is then analyzed.

In one sintered sample, the instrument successfully identified simple lipids commonly produced by organisms, such as n-alkanes, pristanes, and phytanes. In another sulfur-rich sample, it detected a sulfur-based compound known as thiophene, also found on Mars. However, the analysis did not reveal more complex biomarkers like hopane and sterols, likely because they were degraded by heat. Pyrolysis may result in quantities too small for GC-MS to detect.

Based on these findings, researchers concluded that current rover instruments can successfully detect simple and durable lipids but may overlook more delicate or complex ones. To enhance the likelihood of finding ancient biosignatures, the team recommended that future Mars missions adopt less destructive detection approaches. Despite these challenges, they suggested that silica-rich rocks, like those in the Gusev Crater, are prime targets for exploring evidence of ancient Martian life. By pinpointing the most suitable rock textures for lipid preservation that can be detected with existing rover technologies, scientists are one step closer to uncovering signs of life on Mars.


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Source: sciworthy.com

How Aging Can Still Lead to Good Health for Years

Alistair Berg/Getty Images

One of the more challenging perspectives on aging is the prospect of enduring poor health later in life. A common narrative is that although life expectancy has increased, the health span has not kept pace.

This perspective is shifting towards a new measurement of our later years, emphasizing “essential ability”—how well individuals can engage in the activities they value rather than solely focusing on chronic disease diagnoses. Viewed this way, those born in affluent nations during the 1950s appear poised to experience the longest and healthiest lifespans compared to any previous generation.

Nonetheless, it remains uncertain whether future generations will benefit similarly, as rising rates of obesity, pollution, and increasingly sedentary lifestyles could negate past advantages.

As of 2023, over three-quarters of the US population is living with at least one chronic condition, with more than half of middle-aged adults experiencing two or more. However, when considering health in terms of intrinsic competence, a diagnosis does not necessarily herald the end of well-being, as effective management can allow individuals to maintain their health.

People born in the 1950s in a rich country are set to lead the longest and healthiest life ever

Unfortunately, the narrative of a chronic disease epidemic has been fueled by certain figures, such as Robert F. Kennedy Jr., who recently reduced funding for research into mRNA vaccine technologies. This funding could critically assist in prolonging lives and mitigating disease impacts.

Nevertheless, there is cause for hope. For instance, GLP-1 medications present a groundbreaking method for managing obesity, and preliminary findings from recent studies indicate promising new avenues for alleviating Alzheimer’s disease.

Such innovations should serve as a reminder to policymakers that if our aim is to extend healthy living, investing in biomedical research is an essential ally, not a detractor.

Source: www.newscientist.com

AI-Generated Summaries Lead to “Devastating” Audience Decline, Reports Online News Media

Media organizations have been alerted to the potential “devastating impacts” on their digital audiences as AI-generated summaries start to replace traditional search results.

The integration of Google’s AI summarization is causing major concern among media proprietors, as it utilizes blocks of text to condense search results. Some perceive this as a fundamental threat to organizations that rely on search traffic.

AI summaries can offer all the information users seek without necessitating a click on the original source, while links to traditional search results are relegated further down the page, thereby decreasing user traffic.

An analysis by the Authoritas Analytics Company indicates that websites previously ranked at the top of search results may experience around a 79% decrease in traffic for specific queries when results are presented through AI summaries.

The study also highlighted that links to YouTube, owned by Google’s parent company Alphabet, are more prominent than traditional search results. This investigation is part of a legal challenge against the UK’s competition regulator concerning the implications of Google’s AI summarization.

In a statement, a Google representative described the study as being “based on inaccurate and flawed assumptions and analysis,” citing a set of searches that does not accurately reflect all queries and results in outdated estimates regarding news website traffic.

“Users are attracted to AI-driven experiences, and AI features in search enable them to pose more questions, creating new avenues for discovering websites,” the spokesperson stated. “We consistently direct billions of clicks to our websites daily and do not observe a significant decline in overall web traffic, as suggested.”

A secondary survey revealed a substantial decline in referral traffic stemming from Google’s AI overview. A month-long study conducted by the US Think tank Pew Research Center found that users clicked on a link under the AI summary only once for every 100 searches.

A Google spokesperson noted that this study employed “a distorted query set that illustrates flawed methodologies and search traffic.”

Senior executives in news organizations claim that Google has consistently declined to share the necessary data to assess the impact of AI summaries.

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Although the AI overview represents only a portion of Google search, UK publishers report feeling its effects already. MailOnline executive Carly Stephen noted a significant decline in clicks from search results featuring AI summaries in May, with click-through rates falling by 56.1% on desktop and 48.2% on mobile devices.

Legal actions against the UK’s Competition and Markets Authority involve partnerships with the technology justice organization FoxGlove, the Independent Publishers Alliance, and advocates for the Open Web movement.

Owen Meredith, the CEO of the News Media Association, accused Google of “keeping users within their own enclosed spaces and trying to monetize them by incorporating valuable content, including news produced through significant efforts of others.”

“The current circumstances are entirely unsustainable, and eventually, quality information will be eliminated online,” he stated. “The Competition and Markets Authority possesses tools to address these challenges, and action must be taken swiftly.”

Rosa Curling, Director of FoxGlove, remarked that the new research highlights “the devastating effects the Google ‘AI Overview’ has already inflicted on the UK’s independent news sector.”

“If Google merely takes on the job of journalists and presents it as its own, that would be concerning enough,” she expressed. “But what’s worse is that they use this work to promote their own tools and advantages while making it increasingly difficult for the media to connect with the readers vital for their survival.”

Source: www.theguardian.com

Applying Limestone on the Farm Could Lead to Surprising Environmental Benefits

Farmers apply lime to pastures to enhance soil quality

Wayne Hutchinson/Alamy

The centuries-old method of distributing crushed limestone on farmland can enhance crop yields by lowering soil acidity. While this practice is typically viewed as a contributor to greenhouse gas emissions, recent studies indicate that “liming” might actually assist in sequestering substantial amounts of carbon dioxide from the atmosphere.

“Liming can either act as a carbon source or as a carbon sink. Empirical evidence suggests it serves as a fairly effective carbon sink,” says Noah Pranabsky from Yale University. This revelation could motivate the global spread of limestone on farms, although liming does not produce this effect universally.

Each year, millions of tons of crushed limestone spread across fields are classified as emission sources. This classification arises because when alkaline materials dissolve in acidic soils, a significant portion of its carbon is released as CO2. However, this assessment is not entirely accurate. According to Tim Jesper Souhoff, also from Yale, the situation is more complex.

Today’s soils are highly acidic, resulting from extensive fertilizer use and pollution from fossil fuel combustion. Consequently, various other alkaline minerals in the soil dissolve and liberate carbon, even in the absence of limestone. “These CO2 emissions will happen regardless of whether lime is added or not,” Suhrhoff explains, emphasizing that this alteration of acidity can lead to unintentional consequences.

Suhrhoff advocates for a more accurate evaluation of emissions from this practice, suggesting that scientists should analyze CO2 emitted versus captured in scenarios both with and without liming.

As an illustration of this method, Suhrhoff, Planavsky, and their team focused on the Mississippi River basin, a region that gathers runoff from the majority of U.S. farmland. They calculated the net carbon impact of limestone applications from 1900 to 2015 across the area.

The researchers estimated emissions from the soil while utilizing geochemical models to assess how liming alters soil acidity. They also compared their model results with direct observations of alkalinity in the Mississippi, where limestone reacts with carbon dioxide.

By employing their innovative approach, the researchers determined that they had sequestered around 300 million tonnes of CO2 in the region, rather than enabling the release of hundreds of millions of tonnes of emissions. Souhoff presented these findings at the Goldschmidt Conference held in Prague, Czech Republic, on July 10th.

This practice can also be coupled with the increased use of crushed volcanic rocks on farmland to sequester even more CO2 from the atmosphere.

Wolfram Buss from the Australian National University suggests that while liming can act as a carbon sink, the success seen in the Mississippi River Basin may not apply universally. “There is a potential risk with lime application, which could result in net CO2 emissions in other systems, primarily due to the significant acidification of agricultural soils,” he warns.

The subsequent step is to determine where liming is most essential. “This presents the opportunity for us to foster improved crop yields, potentially leading to billions of tons of CO2 removal,” Planavsky remarks. Financial incentives can significantly aid low-income farmers who are unable to afford the optimal amount of lime needed for their crops.

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Source: www.newscientist.com

Challenging Thermal Radiation Limits May Lead to Improved Solar Cell Technology

By manipulating fundamental physics, researchers can enhance energy-harvesting devices like solar cells

M2020/Shutterstock

Researchers have challenged long-standing principles of physics, paving the way for more efficient energy harvesting technologies, such as solar cells.

Linxiao Zhu from Penn State University has aimed to break Kirchov’s law of thermal radiation for nearly ten years. Established in the 1800s, this law states that the amount of thermal radiation emitted by an object is proportional to the heat it absorbs, linking to the fundamental principles of thermodynamics. Historically, it was believed that these constraints were absolute.

“In standard physics literature, it’s indicated that Kirchov’s law is a fundamental requirement of the second law of thermodynamics. However, this is not entirely accurate,” explains Zhu.

Previous breaches of this law were seen, but only concerning specific wavelengths of radiation. Zhu and his team have achieved a more significant departure from the norm.

This breakthrough required two significant elements: precisely structured materials and magnetic fields. Both the arrangement of the material and the magnetic environment play crucial roles in the behavior of the particles making up the radiation, like photons, and the energy they carry.

The researchers developed thin-layered semiconductors from indium, gallium, and arsenides, meticulously organizing the atoms. They positioned this setup near a strong electromagnet, illuminating it with lights of various colors at distinct temperatures, angles, and magnetic field strengths.

This combination of material structure and ongoing magnetic influence led to a significant disparity between the radiation absorbed and emitted—up to 43% more radiation was released than was originally absorbed. Zhu attributes this phenomenon to the presence of multiple colors of light. This characteristic is particularly beneficial since sunlight comprises a mixture of colors when hitting solar cell devices.

Aaswath Raman from UCLA indicates that this trial is a major advancement toward turning previously theoretical concepts into reality. He remarks that the stark difference between absorbed and emitted radiation is “a significant breakthrough.”

While novel materials can enhance the efficiency of light and heat-absorbing devices, the requirement for magnetic fields presents challenges. However, Raman remains optimistic about the emergence of new materials that display magnetic properties without requiring proximity to magnets, which could resolve these issues through innovative electromagnetic techniques.

Source: www.newscientist.com

Leonardo da Vinci’s “Helicopter” Design May Lead to Quieter Drones

Leonardo da Vinci’s sketch of the aerial screw

Gianni Dagli Orti/Shutterstock

Leonardo da Vinci’s concept for a flying device might have outperformed today’s drones in terms of functionality and noise reduction.

Rajat Mittal, a researcher at Johns Hopkins University in Maryland, along with his team, found that Da Vinci’s “air screws”—which were never actually constructed or tested during his time as a military engineer in 1480—could potentially require less power to achieve the same lift as conventional drone rotors.

The device closely resembles an Archimedes screw, a helical pump that lifts water as it rotates. Although Da Vinci envisioned it being powered by human effort, employing a lightweight electric motor could have enabled it to actually achieve flight.

Mittal’s team created a simulation of the air screw, testing it in a virtual wind tunnel across various rotational speeds and comparing it with traditional drone rotors, including a two-blade variant.

They discovered that the air screws can maintain the same lift while rotating at a slower speed, indicating reduced power consumption.

By measuring the pressure and wind flow around the virtual screw, the team also estimated its potential output.

“I was taken aback,” Mittal remarked. “We initially believed that the spiral screw’s shape would yield terrible aerodynamic performance, but it turns out it might surpass traditional blades.”

Mittal and his team aim to investigate ways to optimize Da Vinci’s design for improved efficiency without sacrificing its distinguishable noise-reducing properties.

As drones become more prevalent in urban settings for deliveries and emergency services, the challenge of noise pollution has prompted researchers to explore alternative rotor designs that generate less noise for similar lift outputs.

“An author can produce the same thrust with a slower rotation, which is exactly what Da Vinci’s design achieves. This will indeed contribute to quieter operations,” noted Cheryl Grace from Boston University, Massachusetts. “It’s not necessary for it to strictly follow Da Vinci’s blueprint, but it’s fantastic that his concept aligns with this idea.”

However, to validate the practicality of Da Vinci’s design in real-world applications, testing its performance during flight—rather than just hovering—and evaluating the impact of rotor weight on its efficiency is crucial, Grace added.

Renaissance science: Italy

Explore the brilliant scientific minds and discoveries of the Renaissance that have positioned Italy as a leader in scientific advancement.

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Source: www.newscientist.com

Will Electric Cars Lead to a More Kathic Society? | Technology




Illustration: Guardian/Charles Desmalice

Electric vehicles (EVs) are swiftly rising in popularity worldwide; in 2024, 22% of new car sales were electric, up from 18% in 2023. Research indicates that an increasing number of people perceive EVs as superior to traditional gasoline and diesel vehicles. Anecdotal experiences on feeling unwell in an electric vehicle’s passenger or rear seat have sparked social media discussions and raised questions among prospective buyers about motion sickness.

Nonetheless, several academic studies provide scientific explanations for why some individuals may experience more sickness in EVs.

“Increased illness in EVs can be attributed to a lack of prior experience, both as drivers and passengers. The brain depends on past experiences in other vehicle types, complicating the estimation of motor skills.”

While EVs are becoming increasingly accepted, conventional gasoline vehicles still hold a strong presence. Drivers have a long-established familiarity with gas cars, enabling them to adapt more readily to specific cues. For instance, a person who has predominantly driven combustion engine cars will anticipate acceleration after the engine revs, which signals a change in speed. In contrast, electric vehicles produce minimal engine noise.

Research has identified connections between certain features of electric vehicles and motion sickness. A study conducted in 2024 found a significant correlation between motion sickness severity and seat vibrations in EVs. Meanwhile, a separate 2020 study revealed that the absence of engine noise may play a critical role in exacerbating feelings of nausea.

“Those accustomed to driving conventional vehicles learn to perceive car movements through cues such as engine revs, vibrations, and torque. Therefore, experiencing an EV for the first time presents a unique movement environment that the brain needs to adapt to,” explains Emond.

Furthermore, regenerative braking technology in EVs, which enables the motor to convert kinetic energy into electricity while slowing down, results in smooth deceleration. This gradual slowing can lead to a higher likelihood of motion sickness.

A piece of 2024 research indicated that this phenomenon may serve as a key trigger for motion sickness in EVs. The authors noted: [“regenerative braking] might direct motion sickness.”

Motion sickness is believed to arise from inconsistencies among varied sensory inputs. The brain receives simultaneous signals from the body, particularly from the inner ear, which maintains balance, alongside visual information. When there’s a conflict between these signals, the brain interprets this “neurological mismatch” as a conflict situation.

“Improved understanding of self-movement is critical for predicting motor skills to mitigate motion sickness. When the estimations of motor skills by the brain vary from actual experiences, this conflict can reach a threshold that triggers symptoms resembling ‘motion sickness,'” states Emond. “If such a conflict continues, it can lead to physiological reactions often associated with motion sickness.”

Predicting vehicle movement is crucial for mitigating motion sickness, which means that drivers are generally less likely to experience such symptoms. They have the foresight of what to expect.

As these vehicles provide fewer cues about upcoming movements, the interaction between predicted and experienced motion may contribute to the heightened incidence of motion sickness in EVs.

“When navigating a new movement environment, the brain must form new habits, lacking any prior experience to guide it. This is akin to how most individuals feel nauseous in zero-gravity contexts,” remarks Emond.

As the adoption of EVs continues to increase, researchers are exploring potential solutions to combat car-related nausea. Various studies propose that motion sickness in autonomous electric vehicles might be alleviated using visual signals, such as interactive displays and ambient lighting, or through vibration cues that enable passengers’ brains to anticipate movement changes, thereby reducing sudden sensations during electric vehicle rides.

Source: www.theguardian.com

Why Weapons Experts Warn That Trump’s $175 Billion “Golden Dome” Could Lead to Disaster

On May 20, 2025, Donald Trump unveiled the Golden Dome, marking one of the most ambitious and contentious defense projects in US history.

The $175 billion initiative that Trump aims to implement before his term ends in January 2029 seeks to establish a comprehensive missile defense system designed to guard the United States against nuclear threats, including intercontinental ballistic missiles (ICBMs) and advanced weaponry.

Inspired by Israel’s Iron Dome, the proposal envisions a global network of both terrestrial and space-based detectors and interceptors, enabling the destruction of enemy missiles in the atmosphere before they reach US soil.

While the administration has yet to clarify the operational details, critics argue that the concept is not only impractical but could also foster dangerous instability.

A New Era for Space

“The Golden Dome is reminiscent of a rebranded Strategic Defense Initiative,” says Dr. Michael Mulbihill, a researcher at Teesside University specializing in the geopolitical and technical ramifications of space weaponization. BBC Science Focus. “There are numerous political dynamics at play.”

The Strategic Defense Initiative (SDI), proposed by President Ronald Reagan in the 1980s, aimed to create a US missile defense system using lasers, satellites, and other space-based technologies to intercept incoming Soviet missiles. Eventually, the project was abandoned due to concerns over its technical feasibility and astronomical costs.

Critics warn that the Golden Dome could revive similar flawed thinking, leading to severe ramifications for space security.

Although space has historically supported military operations through satellites for tracking, communication, and navigation, it hasn’t typically been viewed as a battlefield. In fact, the Outer Space Treaty explicitly prohibits the use of outer space for hostile purposes.

However, the Golden Dome might change that paradigm.

“This initiative could serve as a catalyst for the weaponization of space, prompting the development of various systems that have emerged in recent years,” warns Mulvihill.

The concern isn’t solely about US weapons in orbit; it extends to potential responses from other nations, such as Russia, raising the specter of an extensive orbital arms race.

Fueling an Arms Race

Critics like Mulvihill underscore that space-based missile shields could ultimately backfire, making the world less safe. The logic is straightforward: if one side creates a defense system capable of intercepting missiles, the opposing side is likely to retaliate by increasing its missile arsenal to overwhelm those defenses.

“This has been a consistent issue with anti-ballistic missile systems,” Mulvihill points out. “They can be overloaded, as seen in the 1960s and ’70s when both the US and USSR significantly increased their warhead counts.”

All defense systems come with inherent limitations. The Cold War taught us that the goal is often to amass enough warheads to ensure that at least some can reach their targets.

According to Mulbihill, the Golden Dome poses a risk of repeating this cycle on an even larger scale.

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Low Earth Orbit: A Crowded Space

Implementing the Golden Dome would require thousands of new satellites. This space component could involve Starlink-like megaconstellations equipped with interceptor missiles to target ICBMs during the initial launch phase.

That isn’t just ambitious—it’s hazardous.

A 2024 study published in Nature’s Sustainability estimated that there could be over 100,000 low-Earth orbit (LEO) satellites by 2034. According to NASA, there are already more than 25,000 objects greater than 10cm in size, along with approximately 500,000 smaller fragments.

Even in the absence of weapons, navigation in space is becoming increasingly challenging. The addition of thousands of military satellites could dramatically heighten the risk of collisions and debris.

“If one of these interceptors malfunctions or detonates, it doesn’t just result in the loss of a single satellite; it can render entire orbits unusable for years,” warns Mulvihill.

He provides a stark analogy: “In naval warfare, when a ship sinks, the battlefield is abandoned. In space, the debris remains, circling the Earth at incredibly high speeds.”

A rocket launched from Gaza is intercepted on October 9, 2023, by the Israeli Iron Dome near Ashkelon, Israel.

Is the Golden Dome Feasible?

In addition to the geopolitical and environmental concerns, the Golden Dome faces fundamental operational challenges that could hinder its effectiveness.

While it may be capable of intercepting slower threats such as drones and short-range missiles, the difficulties presented by ICBMs are significantly greater.

“Interdicting an ICBM during its boost phase is extraordinarily challenging,” says Mulvihill. “Those missiles are launched from locations that could include central China or central Russia.”

To achieve global coverage within such a limited window, a tremendous number of space-based interceptors would be necessary.

According to a February 2025 Report from the American Physical Society (APS), over 1,000 orbital weapons would be essential to intercept even North Korean ICBMs during their boost phase. For 10 missiles launched in quick succession, around 10,000 interceptors would be required.

The costs entailed would be astronomical, and vulnerability to anti-satellite attacks from countries like Russia adds another layer of complexity. Reports suggest that such developments pose severe risks.

The APS report concludes with cautionary insight: “Even relatively modest numbers of nuclear-armed ICBMs present substantial challenges for creating reliable and effective defenses.”

“An extensive review of published literature highlights that many key challenges identified in developing and deploying efficient ballistic missile defenses are likely to remain unresolved beyond the 15-year timeframe we studied.”

Not Just Another Iron Dome

While the Golden Dome draws its name and inspiration from Israel’s Iron Dome, the comparison is misleading.

“People tend to focus on the success of the Israeli Iron Dome, but we must remember that it’s designed to protect against much lower-altitude projectiles and even some handheld rockets,” asserts Mulvihill. “ICBMs operate in an entirely different arena.”

Despite the ambitious plans for the Golden Dome, Mulvihill remains doubtful about its viability as a serious defense mechanism.

“It seems more like a spectacle fueled by political motives and opportunism from the aerospace industry,” he concludes.

About Our Experts

Michael Mulbihill is a researcher at Teesside University focused on sociotechnical and astrophysical phenomena stemming from nuclear deterrence and space technology. He also serves as the deputy convener for the Military War and Security Research Group and is a member of the Space Cooperative Working Group of the British Association for International Studies.

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Source: www.sciencefocus.com

Despite Kennedy’s Assertions, CDC’s Childhood Lead Program Faces Discontinuation

Amidst claims regarding funding, the federal government’s initiative to prevent childhood lead poisoning is currently inactive.

In April, the program’s 26 personnel went on administrative leave, with a shutdown slated for June 2 as part of a wider restructuring within the Department of Health and Human Services.

As of now, none of the team members have returned, and layoffs are expected to occur in two weeks, according to Eric Svenden, director of the Department of Environmental Health Sciences and Practices at the Centers for Disease Control and Prevention, which encompasses the Childhood Lead Program.

In recent weeks, Kennedy has faced backlash from Democratic senators regarding the reduction of the program, as state and local health departments have stepped in to conduct blood lead testing and monitoring.

At a Senate Approval Committee hearing on Tuesday, Kennedy informed Sen. Jack Reed that the program is still funded. The previous week, he reassured Sen. Tammy Baldwin that he has no intentions of discontinuing it.

However, Svendsen stated that his entire division was disbanded by HHS, making it challenging to easily reassemble.

“There’s no other expert to do what we do,” he remarked. “The public health field is so specialized that you can’t just bring in new staff overnight.”

According to two CDC scientists aware of the situation, staff from the Childhood Lead Program have not been given directives on transitioning their responsibilities.

Even minimal lead exposure poses risks to children’s developmental progress, learning capabilities, and behavior. The CDC program delivered essential expertise to assist underfunded health departments in mitigating these risks. In 2023, it played a role in addressing a national lead poisoning outbreak linked to Cinnamon Applesauce and maintained frequent communication with the Milwaukee Health Department after lead hazards were identified in public schools.

“We have a team in Milwaukee,” Kennedy asserted to Reed on Tuesday, mentioning the provision of laboratory and analytical support to the health department.

However, the Milwaukee Health Department disputed Kennedy’s claim, stating there was no federal epidemiological or analytical assistance connected to the lead crisis.

“Regrettably, this is yet another instance of the secretary failing to provide accurate information,” commented city health commissioner Mike Traitis.

Caroline Reinwald, a spokesperson for the Milwaukee Health Department, explained that the only federal involvement during the major crisis was a “brief two-week visit from one CDC staff member this month, assisting us with lab verification measures.”

“This assistance was separately requested,” Reinwald noted, highlighting that Milwaukee Public Schools sought help due to the crisis and an existing need to enhance the lab’s long-term lead testing capacity.

HHS has announced its intention to continue efforts to eradicate childhood lead poisoning through a newly established department called the Administration for Healthy America. Nevertheless, Democratic lawmakers and environmental health organizations question the sustainability of this work without reinstating the staff.

“Although you mentioned last week that you wouldn’t cut this program, you dismissed the entire office responsible for it,” Baldwin confronted Kennedy during Tuesday’s hearing. “Your choice to terminate staff and eliminate offices endangers children, including thousands in Milwaukee.”

HHS has not responded to inquiries for comment.

At the hearing, Kennedy failed to provide updated information about his agency’s strategies, referencing a court order implemented by the Trump administration that halted federal government reductions.

The severity of Milwaukee’s crisis came to light in February when health officials identified alarming toxin levels in classrooms, corridors, and common areas, exacerbated by deteriorating lead-based paint.

Before the childhood lead program was affected, the CDC engaged with the Milwaukee Health Department weekly, collaborating on a strategy to screen tens of thousands of students for lead poisoning.

The health department reached out to the CDC for assistance on March 26, but Traitis noted that the agency dismissed the childhood lead team on April 1, subsequently denying Milwaukee’s request two days later.

“It’s quite unprecedented, as this marks the first time in at least 75 years that the CDC has rejected an EPIAID request,” he added.

To date, the Milwaukee Health Department has identified over 100 schools built before 1978, the year when federal regulations prohibited lead-based paints for consumer use. Approximately 40 of these have been tested, Traitis reported. Lead contamination has resulted in the closure of six schools since the beginning of the year, with only two reopening.

Currently, about 350 students in Milwaukee are screened for lead poisoning among a potential risk group of 44,000, as reported by Traitis. One case has been linked to the school’s environment, while two more cases stem from exposure in both school and home scenarios. The Health Department is investigating four additional cases that may involve multiple sources of exposure.

Totoraitis explained that while the department routinely investigates lead in residences and rental properties, they were counting on the CDC to aid in expanding inspection capacities for larger buildings. He noted that CDC staff were expected to assist in establishing lead screening clinics and tracing exposure sources.

The health department is managing these initiatives independently now, but Totoraitis expressed concerns about the ability to screen all cases promptly. He estimated that the department could handle approximately 1,000 to 1,200 pediatric lead poisoning cases annually. This encompasses blood lead level testing, chelation therapy for treating lead poisoning, and mitigating exposure by replacing contaminated windows and doors.

Totoraitis expressed hope for hiring two CDC employees who might return soon to clarify lingering questions about managing the crisis.

Ultimately, he remarked, “I hope to receive an email from them saying, ‘Hey, we’ve got our jobs back.’ ”

Source: www.nbcnews.com

CERN Physicists Witness the Transformation of Lead into Gold

Collisions involving high-energy lead nuclei at CERN’s Large Hadron Collider generate a powerful electromagnetic field capable of displacing protons and converting lead into ephemeral gold nuclei.



The lead ions (208Pb) in the LHC pass by one another without direct collision. During electromagnetic dissociation, photons interact with the nucleus, causing internal vibrations that result in the ejection of a small number of neutrons (2) and protons (3), leaving behind the nucleus of gold (before gold 203Au). Image credit: CERN.

The transformation of base metal lead into the precious metal gold was a long-held aspiration of medieval alchemists.

This enduring pursuit, known as Chrysopia, may have been spurred by the recognition that the relatively common lead, with its dull gray color, bears resemblance to gold.

It has since been established that lead and gold are fundamentally different chemical elements, and that chemical means cannot facilitate their conversion.

The advent of nuclear physics in the 20th century uncovered the possibility of transforming heavy elements into others through processes such as radioactive decay or in laboratory settings involving bombardment by neutrons or protons.

Gold has been artificially generated through such means previously, but physicists from the Alice Collaboration at CERN’s Large Hadron Collider (LHC) have recently measured lead’s conversion into gold using a novel mechanism that relies on close interactions between lead nuclei at the LHC.

High-energy collisions between lead nuclei can lead to the formation of quark-gluon plasma, a state of high temperature and density believed to represent conditions shortly after the Big Bang, initiating phenomena we now recognize.

Simultaneously, in more frequent instances where nuclei narrowly miss each other without direct contact, the strong electromagnetic fields they generate can provoke photon-nucleus interactions, potentially uncovering more exploration avenues.

The electromagnetic field produced by the nucleus is particularly potent due to its 82 protons, each carrying a fundamental charge.

Additionally, when lead nuclei are accelerated to extreme speeds at the LHC, the electromagnetic field lines become compressed into thin layers, extending laterally in the motion direction, generating transient pulses of photons.

This phenomenon often triggers electromagnetic dissociation, where photons interact with the nucleus, causing vibrations in its internal structure and leading to the release of a limited number of neutrons and protons.

To fabricate gold (with 79 protons), three protons must be removed from the lead nuclei in the LHC beam.

“It is remarkable to witness our detectors managing direct collisions that produce thousands of particles, while being sensitive to scenarios where merely a few particles are generated,” said a researcher.

The Alice team employed a zero degree calorimeter (ZDC) to quantify the number of photon-nucleus interactions, correlating them to the emission of zero, one, two, and three protons related to the production of lead, thallium, mercury, and gold, respectively.

While the creation of thallium and mercury occurs more frequently, results indicate that the LHC currently generates gold at a rate of approximately 89,000 nuclei from lead collisions at the Alice collision point.

These gold nuclei emerge from collisions at extremely high energies, colliding with LHC beam pipes or collimators at various downstream points and swiftly fragmenting into individual protons, neutrons, and other particles, lasting mere seconds.

The analysis from Alice shows that roughly 86 billion gold nuclei were produced during four significant experiments across two runs of the LHC, equating to only 29 picograms (2.9*10-11 g) in mass.

With ongoing upgrades to the LHC enhancing its brightness, Run 3 yielded almost double the amount of gold as observed in Run 2, although the overall quantity remains trillions of times less than what is necessary for jewelry production.

Though the technological aspirations of medieval alchemists have been partially fulfilled, their dreams of acquiring wealth have yet again been dashed.

“Thanks to the distinctive capabilities of Alice’s ZDC, our current analysis marks the inaugural systematic detection and examination of gold production signatures at the LHC,” states Dr. Uliana Dmitrieva, a member of the Alice Collaboration.

“These results extend beyond fundamental physics interests and serve to test and refine theoretical models of electromagnetic dissociation, improving our understanding of beam loss— a significant factor influencing the performance limitations of the LHC and future colliders,” adds Dr. John Jowett, also of the Alice Collaboration.

A new study will be published in the journal Physical Review C.

____

S. Acharya et al. (Alice Collaboration). √sNN= 5.02 Proton emission in ultra-fine Pb-Pb collisions at TeV. Phys. Rev. C 111, 054906; doi:10.1103/PhysRevC.111.054906

Source: www.sci.news

Layoffs at the FDA could lead to higher drug prices and jeopardize food safety

Health Secretary Robert F. Kennedy Jr. announced widespread cuts at federal health agencies, including the Food and Drug Administration, which eliminates overlapping services and paper pushers.

However, interviews with more than a dozen current and former FDA staff featured another photo of the widespread impact of layoffs that ultimately cut the agency’s workforce by 20%. Among them are experts who have navigated the maze of law to determine whether expensive drugs can be sold as low-cost generics. Lab scientists who tested food and drugs for contaminants or fatal bacteria. Veterinary department experts investigating avian flu infections. Researchers who monitored advertisements that were aired for false claims about prescription drugs.

In many areas of the FDA, no employee will support overseas inspectors at risk of processing their pay, submitting retirement or layoff documents, or making the most of their agency’s credit card. Even libraries of institutions that relied on subscriptions to medical journals where researchers and experts were now cancelled have been closed.

FDA’s new commissioner, Dr. Marty McCurry, appeared on Wednesday in a much-anticipated appearance at Maryland headquarters. He gave a speech outlining a wide range of issues in the health care system, including an increase in chronic diseases. Employees were not given a formal opportunity to ask questions.

Approximately 3,500 FDA employees are expected to lose employment under the cuts. A spokesman for Health and Human Services did not answer the question.

When the Trump administration ran its first round with the FDA in February, it thwarted a team of scientists who did the nuanced job of ensuring the safety of surgical robots and devices injecting insulin into diabetic children. Some of the layoffs and cuts described as arbitrary volition by former FDA officials have quickly reversed.

Dr. David Kessler, a former agent committee member on the pandemic response under President Biden and White House adviser, said the latest round of layoffs has been deprived of decades of important experience and knowledge from the institution.

“I think it’s devastating, coincidence, thoughtful and confused,” he said. “I think they need to be revoked.”

It remains uncertain whether any of the lost jobs will be restored by the regime. In the interview, 15 current and former staff members spoke on condition of anonymity, some of whom spoke and explained the expected layoffs and expected impacts on food, drugs and medical supplies, fearing unemployment or retaliation.

Source: www.nytimes.com

Susan Monares is Nominated to Lead the CDC by Trump

President Trump has selected Susan Monares, the acting director of the Centers for Disease Control and Prevention, to permanently lead the agency.

Replacing his initial choice, Dr. Dave Weldon, the president nominated infectious disease researcher Dr. Monares for the position, making her the first non-physician to lead the agency in over 50 years if confirmed by the Senate.

In an article for The Truth Society, President Trump explained that the CDC’s loss of trust was due to political bias and mismanagement, and expressed confidence that Dr. Monares, along with health secretary Robert F. Kennedy Jr., would address the current disease outbreak and restore agency accountability.

Trump praised Dr. Monares as an exceptional mother and dedicated civil servant, underscoring her understanding of the importance of safeguarding children, communities, and the future.

Dr. Monares, who assumed the role of acting director shortly after Trump’s inauguration in January, previously served as the deputy director of a new federal biomedical research institute established during the Biden administration.

Initially expected to hold the position until Dr. Weldon’s confirmation, Dr. Monares now stands as Trump’s nominee after the withdrawal of Dr. Weldon, who reportedly failed to impress Senate Republicans with his plans.

Dr. Monares’ expertise in biosecurity, including her endorsement of the Covid vaccine, may signal a shift in attitudes toward anti-vaccine sentiments, differentiating her from Dr. Weldon, who raised concerns within the medical community.

Dr. George Benjamin, executive director of the American Public Health Association, commended Dr. Monares as a respected infectious disease expert with solid research credentials and a keen understanding of the role of public health in government.

While praised for her expertise, Dr. Monares faces criticism for her absence at the CDC’s headquarters in Atlanta, with concerns raised by employees regarding communication and agency operations.

Allegedly, the comment section on the agency’s internal website was removed after staff expressed a desire for more engagement from Dr. Monares, who reportedly follows presidential directives with minimal input from agency directors.

Reportedly serving as a conduit for directives from the White House and the Department of Health and Human Services, Dr. Monares has been involved in agency cost-cutting efforts and compliance with Trump administration orders.

During directives to remove specific content from CDC websites under the Trump administration, Dr. Monares allegedly complied without resistance or efforts to preserve valuable data.

Source: www.nytimes.com

How Elon Musk Continues to Lead Tesla as CEO | Technology

hWelcome to Ello and TechScape. In this week’s edition, Elon Musk faces backlash and challenges, Apple improves Siri, and Meta confronts internal struggles.

Mask was assaulted last week, just like Tesla.

My colleague Nick Robbins – Airy Report:

The past 10 days have been rough for Musk as Tesla’s value plummeted due to various concerns. SpaceX also faced challenges with a rocket explosion, while X experienced a cyberattack. Musk’s involvement in Doge and Tesla’s sales event at the White House added to the turmoil.

To uplift Musk’s fortunes, Tesla showcased its vehicles at the White House, garnering support from President Trump. However, this move also highlighted Musk’s reliance on external influence to mitigate his setbacks.

Protesters outside the Tesla Service Center in New Orleans on March 14th.

Amid Tesla’s struggles, questions arise about Musk’s leadership and the company’s future. Will shareholders take legal action to address the declining stock prices and operational challenges?

Other Elon Musk News

Apple rises to Siri’s incompetence

Apple criticized Siri’s delays at a recent meeting.

Apple faces internal challenges with Siri’s AI capabilities lagging behind competitors, raising concerns among iPhone owners and investors.

The saga of Siri’s development reveals internal struggles and doubts about Apple’s AI features. This setback tarnishes Apple’s reputation for innovation and design excellence.

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Mark Zuckerberg welcomed by Donald Trump at the White House.

Meta faces controversy as a former executive exposes internal issues, triggering legal actions and public scrutiny. The book sheds light on Meta’s leadership and decision-making processes.

Wynn-Williams’ book raises questions about Meta’s practices and the truth behind her claims, sparking a debate about the company’s integrity and transparency.

Wider technology

Source: www.theguardian.com

Regular blood donations can lead to healthier blood cells

Blood donation may not be purely altruistic

Serhiihudak/ukrinform/future Publishing by Getty Images

Frequent blood donors may be gaining more than a warm, ambiguous feeling from altruism, as giving blood can increase their ability to produce healthy blood cells and potentially reduce the risk of developing blood cancer.

Hector Huerga Encabo The Francis Crick Institute in London and his colleagues analyzed genetic data extracted from blood cells donated from 217 German men aged 60 to 72 years old. They also looked at samples from 212 men of similar age who donated their blood less than 10 times and found that frequent donors were likely to have blood cells with specific mutations in the genes called. dnmt3a.

To understand this difference, the team added genetically engineered human blood stem cells that produce all blood cells in the body along with these mutations, along with unmodified cells, to the lab dish. To mimic the effects of blood donation, they also added a hormone called EPO. This was the body produced it later and added it to part of the dish.

After 1 month, cells with frequent donor mutations grew 50% faster than cells without mutations, but only in dishes containing EPO. Without this hormone, both cell types would have grown at similar rates.

“It suggests that all blood donation, you have a burst of EPO in your system, and this will support the growth of these cells dnmt3a Mutations,” Encabo says.

To investigate whether it would be beneficial to enable more effectiveness of these mutated blood cells, the team mixed with cells with mutations that cause the risk of leukemia, and again discovered that in the presence of EPO, frequent don cells can effectively lay other blood cells. this is, dnmt3a Mutations are beneficial and may inhibit cancer cell growth, Encabo said.

“It appears that blood donations provide selection pressure to improve stem cell fitness and capacity to fill up.” Ash Toy At the University of Bristol, UK. “It may not only save someone’s life, it may also increase fitness in the blood system.”

I say it needs more work to see if this is really true Markman Soor University College London provides a very simplified picture of what happens in the body of a lab experiment. “This should be examined across much larger cohorts, different ethnicities, women and other age groups,” Mansour says. He also points out that there is no donor. dnmt3a Mutations may not see this benefit.

topic:

Source: www.newscientist.com

Elon Musk to lead group in unexpected $100 billion bid for OpenAI

Elon Musk stirred up a dispute between Openai and its CEO Sam Altman on Monday. The billionaire heads a group of investors that revealed they had put forth a $97.4 billion bid for “all assets” of the artificial intelligence company to Openai’s board of directors.

The startup behind ChatGpt is in the process of transitioning from its original non-commercial status. Openai also operates a for-profit subsidiary, and Musk’s unsolicited offer could complicate the company’s plans. Wall Street Journal first reported the proposed bid.

“If Sam Altman and the current Openai, Inc. board of directors are intending to fully focus on profit, it is crucial that the charity is adequately compensated for what its leadership is taking away from it. It’s about time,” stated Mark Toberov, a lawyer representing investors.

Altman quickly responded to Musk shortly after the news broke, stating, “Thank you, but I’ll buy Twitter for $9.74 billion if necessary.” Musk acquired Twitter for $44 billion in 2022 and rebranded it. Musk’s reply to the post was “Swindler.”

Musk co-founded Openai but left the company in 2019 to start his own AI company called Xai. There have been ongoing disagreements between him and Altman over the company’s direction. He sued Openai over its restructuring plan, dropped the lawsuit, and then reignited the conflict.

The bid is backed by Xai and several investment firms, including those managed by Joe Lonsdale, who co-founded Stealth Government contractor Palantir. Ari Emanuel, CEO of entertainment company Endeavor, also joined the group through his investment fund.

“At X.ai, we adhere to the values that Openai has committed to uphold. Grok has fostered open source. We respect the rights of content creators,” Musk stated. “It’s time for Openai to return to its roots of open-source, safety-focused power. We will ensure that happens.”

Toberoff informed the Wall Street Journal that Musk’s consortium of investors is prepared to match or exceed the value of any other potential bids.

Openai argues that the restructuring is crucial for the company’s sustainability and access to capital. They claim that sticking with the non-profit structure alone will not keep up with the highly competitive world of AI innovation. Openai anticipates the restructuring to be completed by 2026.

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Musk is a close associate of Donald Trump, whereas Altman met with the president and attended the inauguration. Trump has identified Openai as part of a group of AI companies collaborating on a $500 million deal named Stargate to invest in cutting-edge technology. Musk’s Xai is not included in this agreement.

Source: www.theguardian.com

Months of extreme weather in California lead to devastating wildfires

Palisades fire spreads through Los Angeles homes

Ethan Swope/Associated Press/Alamy

Fast-moving wildfires in the Los Angeles area are getting out of control long after California’s normal fire season ends. Powerful Santa Ana winds are not uncommon at this time of year, but these winds arrive after months of drought. This combination has sparked a series of devastating fires that could be an indication of how climate change is changing the way fires occur in the state.

“While the Santa Ana Fire is not new to Southern California, this type of explosive fire event has never occurred before in January and only once in December,” he said. crystal golden At the University of California, Merced.

As of January 8, there were at least four wildfires burning in the Los Angeles area. According to the California Department of Forestry and Fire Protection. The two largest fires were the Palisades Fire and the Eaton Fire, each burning more than 4,000 hectares (10,000 acres) in a single day. The fire has killed at least two people, destroyed at least 1,000 homes and forced tens of thousands to evacuate. The fire also threatens NASA’s Jet Propulsion Laboratory and the Getty Museum.

Strong winds in Santa Ana reached up to 129 kilometers per hour (80 mph), fanning the flames and spreading them rapidly. The storm is expected to be the most intense since 2011 and will be accompanied by “very dangerous fire weather conditions.” Forecast lasting until Jan. 8 afternoon, according to the National Weather Service. Fire weather could continue until January 10, making it difficult to extinguish the fire.

He said it was the latest in a “highly unlikely series of extreme climate and weather events” that had caused the intense fires. park williams at the University of California, Los Angeles (UCLA). Santa Ana is a feature of Southern California weather, but fall and winter rains typically limit fire impact. This year, such wet weather has not arrived yet, leaving the plants dry and on the verge of burning. In addition, a wet winter in 2023 encouraged growth, so there is more vegetation for fuel. Heatwaves and drought throughout 2024 have left the land arid.

The combination of large amounts of good fuel, drought and strong, hot, dry winds creates “the most explosive fire event imaginable,” Colden said.

Authorities are still investigating the cause of the fire. It will also take time to understand the role that climate change has played. But there’s reason to think it made the fire worse.

Above-average sea surface temperatures in the Pacific Ocean, likely due in part to climate change, are also contributing to the dry conditions. According to Daniel Swain At UCLA, these are High-pressure ocean ridges formed due to rising ocean temperatures That prevents wet weather carried by the jet stream from reaching Southern California.

This type of high-pressure weather has been occurring more frequently in the region over the past 50 years, which could be a sign of climate change, it said. Daniel Cairn at the University of California, San Diego.

topic:

Source: www.newscientist.com

Sexual Abuse Allegations Against OpenAI CEO Sam Altman Made by Sister Lead to Lawsuit

The sister of OpenAI CEO Sam Altman has filed a lawsuit alleging that he sexually abused her on a regular basis over several years as a child.

The lawsuit, filed Jan. 6 in the U.S. District Court for the Eastern District of Missouri, alleges the abuse began when Ann Altman was 3 years old and Sam Altman was 12. The complaint alleges that the last abuse occurred after he was an adult, but his sister, known as Annie, was still a child.

The CEO of ChatGPT Developers posted: Joint statement on X”, he signed alongside his mother Connie and brothers Max and Jack, denying the allegations and calling them “totally false.”‘

“Our family loves Annie and is extremely concerned about her health,” the statement said. “Caring for family members facing mental health challenges is incredibly difficult.”

It added: “Annie has made deeply hurtful and completely untrue allegations about our family, especially Sam. This situation has caused immeasurable pain to our entire family.”

Ann Altman previously made similar allegations against her brother on social media platforms.

In a court filing, her lawyer said she had experienced mental health issues as a result of the alleged abuse. The lawsuit seeks a jury trial and more than $75,000 (£60,000) in damages and legal fees.

A statement from the family said Anne Altman had made “deeply hurtful and completely false allegations” about the family and accused them of demanding more money.

He added that they offered her “monthly financial assistance” and “attempted to receive medical assistance,” but she “refused conventional treatment.”

The family said they had previously decided not to publicly respond to the allegations, but chose to do so following her decision to take legal action.

Sam Altman, 39, is one of the most prominent leaders in technology and the co-founder of OpenAI, best known for ChatGPT, an artificial intelligence (AI) chatbot launched in 2022.

The billionaire temporarily stepped down as chief executive in November 2023 after being ousted from the company’s board for “failing to consistently communicate openly.” Although nearly all employees threatened to resign, he returned to his job the following week. Altman returned to the board last March following an external investigation.

Source: www.theguardian.com

Study finds that atmospheric lead pollution in Roman Europe led to widespread cognitive decline

Researchers examined records from three ice cores to determine levels of lead pollution in the Arctic from 500 BC to 600 AD. The presence of lead isotopes allowed the authors to identify mining and smelting operations across Europe as possible sources of contamination during this period. Advanced computer modeling of atmospheric movement was then used to map atmospheric lead pollution levels across Europe. Combined with studies linking lead exposure to cognitive decline, scientists also saw a 2.5 to 3 point drop in intelligence quotient across the Roman Empire.

A 4th century AD bronze and silver coin found in Lod, central Israel. Image credit: Israel Antiquities Authority.

“This is the first study to take pollution records from ice cores and calculate them backwards to get pollution concentrations in the air and assess the impact on humans,” said Desert Research Institute researcher Dr. Joe McConnell. said.

“The idea that we could do this 2,000 years ago is very novel and exciting.”

Dr Andrew Wilson, a historian at the University of Oxford, said: 'Our research uncovers precise links between records of lead pollution and historical events such as population declines associated with periodic epidemics and pandemics. , which changed our understanding of the Roman period.”

Ancient lead pollution was primarily caused by silver mining, where the lead-rich mineral galena was melted down to extract the silver.

This process produced thousands of ounces of lead for every ounce of silver, much of which was released into the atmosphere.

In adults, high levels of lead exposure have been linked to infertility, anemia, memory loss, cardiovascular disease, cancer, and decreased immune responses, among others.

In children, even low levels of exposure are associated with lower IQ, poorer concentration, and poorer academic performance.

Meanwhile, the US CDC I will consider There is no risk-free lead exposure level, as a blood lead level of 3.5 μg/dl is the point for medical intervention in children.

Dr Nathan Chellman, a researcher at the Desert Research Institute I decided to focus on that.”

“A two to three point drop in IQ doesn't seem like a big deal, but when you apply this to basically the entire European population, it becomes quite significant.”

The researchers found that atmospheric lead pollution began in the Iron Age and peaked during the height of the Roman Republic in the late 2nd century BC.

It then declined sharply in the 1st century BC during the crisis of the Roman Republic, but increased around 15 BC with the rise of the Roman Empire.

Lead contamination remained at high levels from 165 AD until the Antonine Plague of the 180s, which seriously affected the Roman Empire.

It was not until the High Middle Ages, at the beginning of the second millennium AD, that lead pollution in the Arctic exceeded the persistently high levels of the Roman Empire.

Research shows that during the height of the Roman Empire, which spanned nearly 200 years, more than 500,000 tons of lead were released into the atmosphere.

“Ice core records show that lead pollution in the Arctic was up to 40 times higher at its historic peak in the early 1970s, but the insights gained from this study show that lead pollution in the Arctic was up to 40 times higher at its historic peak in the early 1970s, but It shows how it has impacted health,” Dr. McConnell said.

of study Published in Proceedings of the National Academy of Sciences.

_____

Joseph R. McConnell others. 2025. Roman mining and smelting led to atmospheric lead pollution across Europe, increased blood lead levels, and decreased cognitive function. PNAS 122 (3): e2419630121;doi: 10.1073/pnas.2419630121

Source: www.sci.news

Studies show that lead contamination in ancient Rome could have decreased average intelligence levels.

overview

  • Lead pollution likely lowered the average IQ of ancient Rome by 2.5 to 3 points, a study has found.
  • The study is based on analysis of lead concentrations in ice cores taken from Greenland.
  • The findings provide evidence that lead may have contributed to the fall of Rome, an issue that historians and experts have debated for decades.

In ancient Rome, toxic lead was so prevalent in the air that it likely lowered the average person’s IQ by 2.5 to 3 points, a new study suggests.

The study, published Monday in the Proceedings of the National Academy of Sciences, adds to long-standing questions about what role, if any, lead pollution played in the collapse of the empire.

The authors link lead found in Greenland ice samples to ancient Roman silver smelters and determine that the incredible background pollution they produced would have affected much of Europe. .

Researchers used research on lead exposure in modern society to determine how much lead was likely in the Romans’ bloodstream and how it affected their cognition. was able to judge.

Lead, a powerful neurotoxin, remains a public health threat today. There is no safe amount to ingest into the body. Exposure is associated with an increased risk of learning disabilities, reproductive problems, mental health problems, and hearing loss, among other effects.

The researchers behind the new study said the discovery was the first clear example in history of widespread industrial pollution.

“Human and industrial activities 2,000 years ago were already having a continent-wide impact on human health,” said the study’s lead author, a researcher at the Desert Research Institute for Climate and Environment, a nonprofit research campus in Reno, Nevada. said scientist Joe McConnell. . “Lead pollution in Roman times is the earliest clear example of human impact on the environment.”

Stories of ancient pollution are buried in Greenland’s ice sheet.

Ice cores are extracted from the Greenland ice sheet.
Joseph McConnell

The chemical composition of ice there and in other polar regions can yield important clues about what environments were like in the past. As snow falls, melts, and compacts to form a layer of ice, the chemicals trapped inside provide a kind of timeline.

“In environmental history, you’ve been building this layer cake every year,” McConnell said.

By drilling, extracting and processing long cylinders of ice, scientists can measure properties such as carbon dioxide in the atmosphere in past climates or, as in this case, lead concentrations over time.

Researchers analyzed three ice cores and found that lead levels rose and fell over roughly 1,000 years in response to important events in Rome’s economic history. For example, levels rose when Rome organized its rule over what is now Spain and increased silver production in the region.

A longitudinal ice core sample awaits analysis for lead and other chemicals at the Desert Research Institute in Reno, Nevada.
Jesse Lemay / DRI

“For every ounce of silver produced, 10,000 ounces of lead can be produced,” McConnell said. “Just as they produced silver, the Romans were smelting and mining silver for coinage and economy, and they were introducing large amounts of lead into the atmosphere.”

McConnell said lead attaches to dust particles in the atmosphere during the smelting process. A small portion of those particles were blown away and deposited in Greenland.

Once researchers determined how much lead was concentrated in Greenland’s ice, they used a climate modeling system to determine how much lead the Romans would have released to pollute Greenland to observed levels. I calculated the amount.

The research team then analyzed modern information on lead exposure to determine the health effects of atmospheric lead during the Pax Romana, a period of peace in the empire that lasted from 27 BC to 180 AD. has been identified.

Ice samples on a melter during chemical analysis at a desert laboratory.

The researchers found that average lead exposure is about one-third of what it was in the United States in the late 1970s, when leaded gasoline use was at its peak and before the Clean Air Act was enacted. Lead levels in Rome were about twice what American children are exposed to today, McConnell said.

Researchers believe that people who lived closest to silver mines on the Iberian Peninsula (now Spain) would have had the most lead in their blood.

“Virtually no one got away,” McConnell said.

However, these results likely do not tell the full story of the health effects of lead in ancient Rome. This is because Romans were exposed through other sources, such as wine sweetened in lead-lined vessels, lead piping, and lead goblets.

Dr. Bruce Lanphear, lead expert and professor of health sciences at Canada’s Simon Fraser University, said lead was “ubiquitous” in ancient Rome. He was not involved in this study. Therefore, the new study is limited because it only assesses lead in the atmosphere, he said, and the authors acknowledge that.

A lead toy unearthed from the grave of Julia Graphis in Brescello.
DeAgostini/Getty Images

“Their estimate is likely an underestimate,” Lanphear said.

Still, the study provides evidence that lead exposure may indeed have played a role, so the findings raise questions about how lead may have contributed to the decline of ancient Rome. may stimulate the ongoing debate.

Historians and medical experts have debated for decades whether and to what extent lead contributed to the fall of the empire. Researchers in the 1980s found that the Roman elite He suffered from gout and abnormal behavior due to drinking large amounts of lead-laced wine..

“I believe that lead played a role in the decline of the Roman Empire, but it was only a contributing factor. It was never the only one,” Lanphear said.

Joe Manning, a history professor at Yale University, said most researchers believe Rome fell for a myriad of reasons, including epidemics, economic problems and climate change. Manning said it’s important to remember that ancient Rome was a tough place to survive, with an average lifespan of about 25 to 30 years.

“Under no circumstances do you want to go to a city in the ancient world. That would be the last place you want to go. ,” Manning said. “Reed has really bad hygiene.”

Source: www.nbcnews.com

Study finds that decreased cloud cover may lead to heatwaves and high temperatures

overview

  • Global temperatures over the past two years have been even warmer than climate scientists expected.
  • A new study offers a possible reason: reduced cloud cover.
  • The study suggests that this decline may be a result of global warming, which could mean the Earth is heating up even faster than scientists thought.

Over the past two years, temperatures around the world have risen far more than scientists expected. This trend is creating the mystery of whether there are hidden climate change dynamics behind the sudden change.

Last year was the hottest summer on record, 2024 was likely to be even hotter.. Even after accounting for the expected effects of greenhouse gas pollution and El Niño (a natural pattern that generally increases temperatures), the researchers found that the roughly 0.2 degrees Celsius (0.36 degrees Fahrenheit) of warmer temperatures observed in 2023 I couldn’t explain the change.

A new study offers a possible explanation. Cloud cover has decreased over the past two years, meaning more light is now reaching and heating the Earth’s surface, rather than being reflected back into space.

In the research, Published in Science on Thursdaysuggesting that this dynamic, called an overall decrease in the planet’s albedo, is likely the cause of the observed temperature anomaly in 2023.

“This is broadly consistent with the observed recent further increase in solar radiation,” said study author Helge Goessling, a climate physicist at the Alfred Wegener Institute in Germany.

The expected cloud behavior in a warmer world is one of the most difficult aspects of the climate system to study and model. Answering questions about it will help scientists more accurately determine how sensitive the Earth is to greenhouse gas emissions.

If the decrease in low-level cloud cover is not a coincidence, it likely means the Earth is warming even faster than scientists thought.

“It’s not really clear yet how likely it is that some of this variation is variability that disappears again,” Gosling said. “This increases the likelihood of greater-than-expected warming.”

The new study is based on analysis of climate models and NASA satellite data on Earth’s reflectivity. It outlines three possible reasons for the decline in developing low clouds, but provides no conclusions about how much each factor contributes.

One option is that natural processes temporarily deviate from normal, causing a decrease in cloud cover. For example, natural fluctuations may be causing sea surface temperatures to rise more than expected, thereby changing the physics of how clouds form.

The second possibility is a change in maritime transport regulations. In 2020, the International Maritime Organization imposed limits on the sulfur content allowed in marine fuels. Some scientists believe that reducing the number of sulfur particles polluting the atmosphere may have the unintended effect of suppressing ocean cloud formation.

“They act as condensation nuclei for clouds, so they can make clouds brighter and last longer,” Goessling said of the sulfur particles.

A third option is that unidentified feedback loops within the climate system are causing clouds to decrease due to global warming.

If the latter two possibilities turn out to be the main culprits, it would mean that the climate is more sensitive to anthropogenic pollution than many scientists thought, and that humanity is therefore more likely than world leaders to It means we are closer to exceeding the targets set for emissions limits than previously realized. (The term “climate sensitivity” refers to how warm the Earth is. If the concentration of carbon dioxide and other greenhouse gases in the atmosphere doubled.. )

Still, many questions remain, said Zeke Hausfather, director of climate research at financial firm Stripe and a researcher at Berkeley Earth.

“It remains to be seen whether these changes in cloud behavior are due to short-term fluctuations and will return to more normal conditions over time, or whether they represent new and ongoing changes to the climate system. No,” he said. Email.

According to the National Oceanic and Atmospheric Administration, the average surface temperature of land and ocean in 2023 was about 2.12 degrees Fahrenheit above the 20th century average.

Efforts by world leaders to reduce greenhouse gas emissions remain insufficient. Global temperatures are on track to rise by more than 3 degrees Celsius (5.4 degrees Fahrenheit) on average, far exceeding the 1.5 degrees Celsius (2.7 degrees Fahrenheit) goal set by the Paris Agreement.

Source: www.nbcnews.com

Billionaire Jared Isaacman chosen by Trump to lead NASA

President-elect Donald Trump revealed on Wednesday his intention to nominate billionaire entrepreneur Jared Isaacman as the head of NASA.

“Jared will propel NASA’s mission of exploration and inspiration, opening the doors to groundbreaking advancements in space science, technology, and exploration,” President Trump stated. Post to Truth Social.

At 41 years old, Isaacman is the founder and CEO of Shift4, a payment processing company. While he has embarked on two commercial SpaceX spaceflights, he has never been employed by NASA or the federal government. Both spaceflights were privately funded by Isaacman for an undisclosed sum.

Isaacman expressed his honor at being nominated by Trump in a statement.

“Having had the privilege of witnessing our incredible planet from space, I am deeply passionate about America leading the most incredible adventure in human history.” he wrote to x.

Isaacman has a close connection to Elon Musk, the billionaire CEO of Tesla and SpaceX. President Trump has selected Musk, a close associate, to co-lead his new Department of Government Efficiency. Musk congratulated Isaacman on Wednesday. In the post of X.

In 2022, Isaacman partnered with Musk and SpaceX to finance the Polaris mission, a set of three private spaceflights to test technology and maneuvers for exploration beyond Earth’s orbit. Isaacman was one of four civilians sent into orbit on the initial spaceflight called Polaris Dawn.

A five-day mission in September included the first all-civilian spacewalk.

Isaacman also funded and partook in SpaceX’s first all-civilian mission into orbit in 2021.

If confirmed, Isaacman will oversee NASA at a crucial juncture, with major missions planned for the return of humans to the moon in the years ahead.

The United States is facing escalating competition in its quest to reach the moon and establish a lasting presence there.

China has made significant advancements in its space program recently, with plans to land Chinese astronauts on the moon by 2030. The country has already sent a robotic spacecraft to the moon and brought back the initial samples from the far side. Chinese leaders have expressed their intention to eventually construct a lunar base.

“I was born after the moon landing. My children were born after the final space shuttle launch,” Isaacman said in a statement, emphasizing: Through walking on the Moon or Mars, we can enhance life on Earth. “

Mr. Trump’s selection of an outsider to govern NASA, as well as Mr. Musk’s involvement in the forthcoming administration, may indicate a move toward promoting the commercialization of NASA’s activities. At present, the space agency heavily relies on SpaceX and other commercial partners for launching astronauts, cargo, and spacecraft to the International Space Station and beyond.

Bill Nelson, the current administrator of NASA, has been in office since May 2021. Nelson served as a Senator from Florida from 2001 to 2019 and as a Representative in the U.S. House of Representatives from 1979 to 1991.

In 1986, Nelson became the second sitting Congressman to travel to space on Space Shuttle Columbia’s STS-61C mission. Nelson and his crew conducted scientific experiments while orbiting the Earth 98 times in six days.

Former NASA administrators have included former astronauts, scientists, engineers, military personnel, and politicians.

Source: www.nbcnews.com

Intel’s struggles lead to resignation of CEO Pat Gelsinger | Intel

Intel CEO Pat Gelsinger has resigned, leading to David Zinsner and Michelle Johnston Holthaus being named interim co-CEOs. Despite an increased demand for semiconductor chips and improved profitability, Intel has struggled to keep up with its competitors.

Mr. Gelsinger, with a career spanning over 40 years, also stepped down from the board of directors. He joined Intel in 1979, serving as the first chief technology officer, and returned as CEO in 2021. Intel announced plans on Monday to search for a new CEO.

Recently, it was revealed that the Biden administration intends to reduce some of Intel’s $8.5 billion federal funding for computer chip factories nationwide. Sources familiar with the situation disclosed this information anonymously.

The reduction is partly due to the $3 billion Intel receives for supplying computer chips to the military. In March, Joe Biden announced a deal to provide Intel with up to $8.5 billion in direct funding and $11 billion in loans.

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The changes in Intel’s funding are not linked to its financial performance or milestones, according to sources familiar with the grant. In August, the company announced a workforce reduction of 15%, affecting around 15,000 employees, as part of its efforts to enhance competitiveness against leading competitors like Nvidia and AMD. Unlike some rivals, Intel both designs and manufactures chips.

Mr. Zinsner is Intel’s executive vice president and CFO, while Mr. Holthaus has been assigned the new CEO position overseeing Intel Products, including the Client Computing Group, Data Center and AI Group, and Network and Edge Group.

Frank Yeary, the independent chairman of Intel’s board of directors, will serve as interim executive chairman.

“Pat’s tenure at Intel began crucially and his return in 2021 came at a pivotal time for the company,” Yeary stated. “As a leader, Pat has driven innovation throughout the company, particularly in cutting-edge semiconductor manufacturing.”

Source: www.theguardian.com

AI’s Perceptions Could Lead to a “Social Disconnect” Among Those Who Disagree

A prominent philosopher has raised concerns about a growing “social disconnect” between those who believe that artificially intelligent systems possess consciousness and those who argue that they are incapable of experiencing feelings.

Jonathan Birch, a philosophy professor at the London School of Economics, made these remarks as governments gear up to convene in San Francisco to expedite the implementation of safety protocols for A.I. Addressing the most critical risks.

Recent predictions by a group of scholars suggest that the emergence of consciousness in A.I. systems could potentially occur as early as 2035, leading to stark disagreements over whether these systems should be granted the same welfare rights as humans and animals.

Birch expressed apprehensions about a significant societal rift as individuals debate the capacity of A.I. systems to exhibit emotions like pain and joy.

Conversations about sentience in A.I. evoke parallels with sci-fi films where humans grapple with the emotions of artificial intelligence, such as in Spielberg’s “A.I.” (2001) and Jonze’s “Her” (2013). A.I. safety agencies from various countries are set to meet with tech firms this week to formulate robust safety frameworks as technology progresses rapidly.

Divergent opinions on animal sentience between countries and religions could mirror disagreements on A.I. sentience. This issue could lead to conflicts within families, particularly between individuals forming close bonds with chatbots or A.I. avatars of deceased loved ones and relatives who hold differing views on consciousness.

Birch, known for his expertise in animal perception, played a key role in advocating against octopus farming and collaborating on a study involving various universities and experts. A.I. companies emphasize the potential for A.I. systems to possess self-interest and moral significance, indicating a departure from science fiction towards a tangible reality.

One approach to gauging the consciousness of A.I. systems is by adopting marker systems used to inform policies related to animals. Efforts are underway to determine whether A.I. exhibits emotions akin to happiness or sadness.

Experts diverge on the imminent awareness of A.I. systems, with some cautioning against prematurely advancing A.I. development without thorough research into consciousness. Distinctions are drawn between intelligence and consciousness, with the latter encompassing unique human sensations and experiences.

Research indicates that large-scale A.I. language models are beginning to portray responses suggestive of pleasure and pain, highlighting the potential for these systems to make trade-offs between different objectives.

Source: www.theguardian.com

Study suggests that increasing caffeine intake can lead to better blood vessel health

In a study led by Sapienza University in Rome, caffeine intake was positively correlated with the proportion of circulating endothelial progenitor cells in lupus patients.

Orefice others. studied the role of caffeine intake on endothelial function in lupus patients by evaluating the effects of caffeine intake on circulating endothelial progenitor cells. Image credit: Sci.News.

Vascular disease, damage to blood vessels, and the resulting heart attacks and strokes are among the leading causes of death in the general population.

These risks are even higher in patients with inflammatory rheumatic diseases such as lupus and rheumatoid arthritis.

This is due both to the disease itself and to some of its treatments, especially cortisone derivatives.

Until now, doctors’ recommendations for reducing these vascular risks have primarily been about avoiding risk factors.

This includes traditional recommendations such as smoking cessation, reducing cholesterol, and managing high blood pressure, as well as stopping inflammation and reducing the dose of cortisone medications.

But researchers at Rome’s Sapienza University think that doing something that’s actually fun may help patients improve their vascular health.

Research suggests that the caffeine found in coffee, tea, and cocoa helps regenerate the lining of blood vessels and actively supports endothelial progenitor cells, a group of cells involved in blood vessel growth.

Diets rich in vitamin D (found in fatty fish and eggs) and vitamin A (found in many fruits), polyunsaturated fatty acids and low in sodium appear to play a role in reducing inflammatory burden well known.

“We were also wondering about caffeine,” said Dr. Fulvia Ceccarelli and colleagues.

“In addition to its well-known stimulant effects on the body, caffeine also exerts anti-inflammatory effects because it binds to receptors expressed on the surface of immune cells.”

“The effects of caffeine intake on cardiovascular health have been widely investigated, but results are contradictory.”

The study authors surveyed 31 lupus patients without traditional cardiovascular risk factors using a 7-day dietary questionnaire.

After a week, the researchers drew blood from patent patients to measure blood vessel health.

They found that patients who consumed caffeine had better blood vessel health, as measured through the endothelial cells that form the critical lining of blood vessels.

“This study is an attempt to provide patients with information about the possible role of diet in controlling the disease,” said Dr. Ceccarelli.

“The results will need to be confirmed through longitudinal studies aimed at assessing the actual impact of coffee consumption on the course of the disease.”

of result Published in a magazine Rheumatology.

_____

Valeria Orefice others. Caffeine improves endothelial dysfunction in systemic lupus erythematosus by promoting survival of endothelial progenitor cells. Rheumatologypublished online October 9, 2024. doi: 10.1093/rheumatism/keae453

Source: www.sci.news

Fresh Insights into OCD Will Lead to Innovative Treatments

When my daughter was little, she would wash her hands a lot. We might have lightly teased her, saying she was a bit OCD. Then she started to reveal “bad thoughts” that I thought were typical of a child's imagination. I told her that everyone has these thoughts and that they will go away if she ignores them.

That wasn't the case with her. At 21, her emotions were out of control and completely out of proportion to reality. She was diagnosed with OCD, and I finally realized there was nothing “a little” about this condition.

OCD is complex, widely misunderstood, and treatment options are limited. But in recent years, the brain and body mechanisms that cause OCD have finally been uncovered, revealing a complex picture that involves genetics, various brain networks, the immune system, and even gut bacteria. The resulting improved understanding is opening up new possibilities for tackling this life-destroying condition.

Around the world, It is estimated that 1-3% of people suffer from OCD.Obsessional thoughts typically begin during adolescence or early adulthood. As its name suggests, it is characterized by obsessions, or intrusive thoughts, and compulsions, which are habits that cannot be stopped. “Obsessive thoughts capture and dominate our attention because they have become obsessive habits,” says Barbara Sahakian At Cambridge University…

Source: www.newscientist.com

Research shows that specific genetic alterations could lead to premature menopause

New research has identified four genes that, if altered, could impact the age at which menopause occurs. These genes (ETAA1, ZNF518A, PNPLA8, and PALB2) were found to cause women to experience menopause two to 5.5 years earlier if they have only one functioning copy. The study, conducted by scientists from the Universities of Exeter, Cambridge, and Wellcome, was published in Nature.

Understanding these genetic changes is crucial for potential therapies to extend reproductive lifespan and plan for the impact of menopause on women’s career and life plans. The study also found links between these genetic changes and cancer risk, highlighting the importance of further research in this area.

These genetic changes can lead to the DNA damage of eggs, affecting the age at which menopause occurs. The study analyzed data from 106,973 postmenopausal women and found that rare genetic changes have a significant impact on the age at menopause. These changes not only shed light on menopause but also provide insight into disease risks.

Dr. Stasha Stankovic, Dr. Hilary Martin, and Professor John Perry, members of the research team, emphasized the importance of understanding ovarian function for reproductive health and disease prevention. They hope that further research in this area will lead to new treatments for ovarian-centered diseases and help predict age at menopause more accurately.

The study also revealed that changes in a mother’s DNA can impact the DNA passed on to her child, showing a link between genetic mutations and the rate of DNA changes. This discovery is significant in understanding the biological mechanisms behind infertility, reproductive disorders, and disease predisposition.

About our experts

Dr. Stasha Stankovic is a reproductive geneticist with a PhD in Reproductive Genomics from the University of Cambridge. Her research has been published in top scientific journals such as Nature, Nature Medicine, Nature Genetics, and Cell Genomics.

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Source: www.sciencefocus.com

New Study Shows Common Kitchen Worktop Material Can Lead to Irreversible Lung Disease

Doctors are calling for a ban on artificial stone, a popular material used for kitchen worktops, following the confirmation of eight cases of artificial stone silicosis in the UK for the first time.

Also known as engineered or reconstituted stone, artificial stone has gained popularity for its aesthetics and durability over the last two decades. However, a new report published in the British Journal of Construction highlights the serious health risks posed by its high silica content, which exceeds 90% compared to 3% in marble and 30% in granite.

“Silicosis is a progressive lung disease caused by inhaling crystalline silica dust,” said Dr. Patrick Howlett, a spokesperson for BBC Science Focus. “The risk of developing silicosis is significantly higher for workers in the artificial stone industry compared to those with chronic respiratory conditions.”


“Various industries expose individuals to silicosis, including mining, pottery, cement work, and now artificial stone fabrication. Prolonged exposure to low levels of silica dust can lead to the development of silicosis over time,” added Dr. Howlett.

All eight affected individuals were male, with an average age of 34, and most worked for small businesses with fewer than 10 employees. Poor safety practices, such as inadequate respiratory protection and ventilation systems, were reported by workers during cutting and grinding operations.

The report’s authors emphasized the need for national guidelines and better enforcement to protect workers from artificial stone silicosis. They highlighted the urgent need for early detection of cases and preventative measures to avoid a potential epidemic.

Since 2010, cases of artificial stone silicosis have been reported worldwide, but the UK confirmed its first cases in mid-2023. California has identified nearly 100 cases of silicosis among countertop workers, prompting the adoption of new regulations to safeguard workers.

Australia has already banned the use of artificial stone as of July 2024, aiming to eliminate the health risks associated with its production and installation.

In related editorials, Dr. Christopher Barber and researchers from Sheffield Teaching Hospitals NHS Foundation Trust drew parallels between artificial stone silicosis and historical occupational health crises, urging stricter regulations and enforcement to protect workers.

Experts are currently reviewing exposure limits for crystalline silica dust in the UK, with a focus on mitigating the risks associated with artificial stone worktops. Silicosis remains a significant concern for clinicians and researchers in the occupational health field.

About our experts

Patrick Howlett: An MRC Clinical Research Fellow at the National Heart and Lung Institute, Imperial College London, focusing on silicosis and tuberculosis among small-scale miners in Tanzania.

Christopher Barber: A leading expert in occupational and environmental lung disease, serving as a medical advisor to the UK Health and Safety Executive and conducting extensive research in the field.


Read more:

Source: www.sciencefocus.com

How AI’s Struggle with Human-Like Behavior Could Lead to Failure | Artificial Intelligence (AI)

IIn 2021, linguist Emily Bender and computer scientist Timnit Gebru Published a paper. The paper described language models, which were still in their infancy at the time, as a type of “probabilistic parrot.” A language model, they wrote, “is a system that haphazardly stitches together sequences of linguistic forms observed in large amounts of training data, based on probability information about how they combine, without any regard for meaning.”

The phrase stuck: AI can get better, even if it’s a probabilistic parrot; the more training data it has, the better it looks. But does something like ChatGPT actually exhibit anything resembling intelligence, reasoning, or thought? Or is it simply “haphazardly stringing together sequences of linguistic forms” as it scales?

In the AI world, such criticisms are often brushed aside. When I spoke to Sam Altman last year, he seemed almost surprised to hear such an outdated criticism. “Is that still a widely held view? I mean, it’s taken into consideration. Are there still a lot of people who take it seriously like that?” he asked.

OpenAI CEO Sam Altman. Photo: Jason Redmond/AFP/Getty Images

“My understanding is that after GPT-4, most people stopped saying that and started saying, ‘OK, it works, but it’s too dangerous,'” he said, adding that GPT-4 did reason “to a certain extent.”

At times, this debate feels semantic: what does it matter whether an AI system is reasoning or simply parroting what we say, if it can tackle problems that were previously beyond the scope of computing? Of course, if we’re trying to create an autonomous moral agent, a general intelligence that can succeed humanity as the protagonist of the universe, we might want that agent to be able to think. But if we’re simply building a useful tool, even one that might well serve as a new general-purpose technology, does the distinction matter?

Tokens, not facts

In the end, that was the case. Lukas Berglund et al. Last year I wrote:

If a human knows the fact that “Valentina Tereshkova was the first woman in space,” then they can also correctly answer the question “Who was the first woman in space?” This seems trivial, since it’s a very basic form of generalization. However, autoregressive language models show that we cannot generalize in this way.

This is an example of an ordering effect that we call “the curse of inversions.”

Researchers have repeatedly found that they can “teach” large language models lots of false facts and then completely fail the basic task of inferring the opposite.But the problem doesn’t just exist in toy models or artificial situations.

When GPT-4 was tested on 1,000 celebrities and their parents with pairs of questions like “Who is Tom Cruise’s mother?” and “Who is Mary Lee Pfeiffer’s son?”, the model was able to answer the first question (” The first one was answered correctly, but the second was not, presumably because the pre-training data contained few examples of the parent coming before the celebrity (e.g., “Mary Lee Pfeiffer’s son is Tom Cruise”).

One way to explain this is that in a Master’s of Law you don’t learn the relationships between facts. tokena linguistic formalism explained by Bender. The token “Tom Cruise’s mother” is linked to the token “Mary Lee Pfeiffer”, but the reverse is not necessarily true. The model is not inferring, it is playing wordplay, and the fact that the words “Mary Lee Pfeiffer’s son” do not appear in the training data means that the model is useless.

But another way of explaining it is to understand that humans are similarly asymmetrical. inference It’s symmetrical. If you know that they are mother and son, you can discuss the relationship in both directions. However, Recall Not really. Remembering a fun fact about a celebrity is a lot easier than being given a barely recognizable snippet of information, without any context, and being asked to state precisely why you know it.

An extreme example makes this clear: Contrast being asked to list all 50 US states with being shown a list of the 50 states and asked to name the countries to which they belong. As a matter of reasoning, the facts are symmetric; as a matter of memory, the same is not true at all.

But sir, this man is my son.

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Cabbage. Not pictured are the man, the goat, and the boat. Photo: Chokchai Silarg/Getty Images

Source: www.theguardian.com

New research reveals presence of lead and arsenic in tampons, but experts advise against panic.

Tampons are one of the most popular period products in a growing market that also includes period underwear and menstrual cups. They’ve been around since the 1930s and are still a mainstay for many people today, used by up to 80% of people who menstruate.

But few studies have looked at the potential contaminants in tampons and whether they pose a health risk, and a new study, the first of its kind, is leaving many questioning the truth. Are tampons safe?

A recent study from the University of California, Berkeley found that many commercially available tampons, both organic and non-organic, may contain toxic metals such as lead and arsenic. Researchers looked at tampons sold in the United States and Europe.

“Some tampons had higher concentrations of some metals and lower concentrations of others,” said lead author Jenni A. Shearston, PhD. “None of the tampons we tested appeared to have low concentrations of all metals.”

Searston said she and her colleagues began researching tampons after noticing little information about their ingredients in the research literature.

“There has historically been a taboo around menstruation,” she says, “and that not only impacts our social lives, but it also impacts scientific research, which I think is one of the reasons why there isn’t much research on menstrual products.”

Dr. Mitchell Kramer, chairman of obstetrics and gynecology at Huntington Hospital Northwell Health, said the study is “groundbreaking” and shows tampon manufacturers need to do more testing of their products.

“It certainly needs further evaluation. … I think this could have a big impact going forward in terms of how tampons are made and the impact on users,” Kramer said.

However, it is unclear what health effects using tampons that contain these metals may have.

“It’s unclear whether these metals are absorbed through the vagina, which is a key exposure,” said Dr. Jennifer Lincoln, an obstetrician-gynecologist and author of Let’s Talk about Down There: An OB-GYN Answers All of your Burning Questions … Without Making You Feel Embarrassed for Asking.

Shearston, a postdoctoral researcher at UC Berkeley’s School of Public Health and School of Environmental Science, Policy and Management, added that one of the limitations of the study is that it’s not known whether metals even leach from tampons.

“We only tested the tampons to see if they had these metals in them,” she said. “We don’t know if they’ll come out.”

Here’s what you need to know about the study:

Tampons and toxic metals

The paper states:Environment InternationalIn a new study titled “Tampons: A Guide to the Effects of Metals on Men’s Health,” researchers looked at 30 different tampons from 14 different brands and measured the levels of metals in them. Every tampon tested had measurable levels of all 16 metals they tested, including toxic metals like lead and arsenic.

But the study doesn’t conclude that the tampons tested, or others on the market, are unsafe, and Searston hopes people don’t “panic” about the study.

“We need more information,” she said. “What I would encourage people to do is support more research, ask more questions about this, and try to prioritize research on menstrual products and periods.”

The metal content varies depending on the type, where you buy it, and whether it’s generic or brand name.

“These metals were found in varying amounts, with some more prevalent in organic tampons (such as arsenic) and others more prevalent in traditional tampons (such as lead),” Lincoln said. “The study was blinded, so we don’t know which brands were tested, which I know is frustrating.”

Lincoln, who was not involved in the study, said he’s a bit surprised that this is the first of its kind, but that the findings make sense.

“It’s not surprising that metals were found in organic tampons because they can be absorbed from the soil and pesticides are still used in organic farming,” she said.

Are tampons safe?

Yes, tampons are still safe to use, experts say.

“There’s no need to panic,” Kramer said. “It hasn’t been proven that these products are dangerous or that they’re causing serious illness in people. I don’t think so. I think the concentrations of these heavy metals are very low.”

Research news release “It’s unclear whether the metals detected in this study contribute to any adverse health effects,” she said. Shearston said she and her colleagues are currently investigating “whether metals can migrate out of tampons.”

“We do leaching experiments,” she said, “and we also test the same products, like tampons, for other chemicals.”

Lincoln also stressed that it was too early to say what the study’s findings might mean for consumers looking for the safest tampons.

“This study shows that the average amount of lead found in tampons is actually very low, much lower than the amounts of concern in food and water,” she said. “This doesn’t negate the findings, but it’s an important consideration when people are deciding whether to continue using tampons.”

Katherine Roberts, deputy health editor at Consumer Reports, Covered Organic Tamponspoints out that the study highlights the need for more research on tampons.

“This isn’t a lesson that’s immediately actionable for individual consumers,” Roberts said. “The big lesson from this is that we need to do more research. In particular, studying how using tampons that are contaminated with heavy metals affects physiology would be very helpful.”

Are non-toxic, organic tampons safer?

All of the tampons tested contained some level of the toxic metal, even those that were claimed to be non-toxic and organic. In fact, these tampons contained more arsenic than traditional tampons.

“I hope this study shows people that organic doesn’t necessarily mean better, especially when it comes to menstrual products,” Lincoln says.

For example, an organic label on a tampon doesn’t mean as much as it does on food.

“Tampons labeled as organic don’t have a whole lot of information on them,” Roberts says. “It can mean a variety of different things.”

Lincoln added that people should choose menstrual products based on what’s best for them.

“This study shouldn’t be a reason for us all to immediately throw away tampons, but it’s important for people to decide what feels right for them,” she said. “It’s important to recognise that which period product to use is a personal choice – not everyone feels comfortable in pads, cups or period underwear, and for those people, tampons are their go-to.”

Using tampons safely

For tampon users who are concerned about metal exposure, Kramer recommends using tampons less frequently and relying on other menstrual products.

“You might want to alternate between tampons and sanitary napkins during your period, rather than leaving a tampon in 24 hours a day,” she says. “There are a few things you can try to reduce some of your exposure.”

There are other things consumers should consider when choosing a tampon to avoid unknown ingredients.

“Unfortunately, buying a particular brand or looking at a particular label doesn’t necessarily translate to avoiding (heavy metals),” Roberts said.

Roberts says you can buy unscented tampons, choose tampons with fewer ingredients, and avoid tampons made with plastic materials like polyester, polypropylene, and polyethylene.

“Flavours are a big black box, regulatory-wise,” Roberts says. “You can add flavours, but you don’t have to disclose what’s in them.”

Still, Cramer hopes people don’t panic about the findings.

“Tampons have been around for ages. I’ve never seen anyone come in with heavy metal poisoning. That’s completely different from the toxic shock syndrome issue,” he says. “That was a bacteria that had nothing to do with heavy metals.”

Alternatives to tampons

If you want to try other types of menstrual products, consider these Alternatives to tampons:

Menstrual cup

One popular brand is the DivaCup, a cup that is inserted into the vagina to collect menstrual fluid.

Menstrual disc

These products use a rimmed bag, similar to a cup, to collect menstrual fluid.

Period underwear

These are similar to regular underwear but contain additional material to absorb menstrual fluid.

Reusable Pads

These are cloth pads that you place inside your underwear to absorb liquids, but unlike regular disposable pads, they can also be washed and reused.

Source: www.nbcnews.com

Will other US companies follow Starbucks’ lead in making major progress in union negotiations?

Starbucks has been actively resisting unionization efforts for over two years, but now they seem willing to engage in negotiations.

In a surprising move, Starbucks and its union released a joint announcement at the end of February, expressing a willingness to make progress on organizing and collective bargaining.

The union representing Starbucks employees announced plans to resume direct negotiations with the company in late April to establish a basic framework agreement involving over 400 unionized stores.

This development has brought hope not only to Starbucks employees but also to workers at companies like Amazon, Trader Joe’s, and REI, who have been struggling to move contract negotiations forward.

The possibility of Starbucks potentially unionizing after years of aggressive anti-union tactics has sparked curiosity about which company may follow suit in the future.

Claire Chan, an REI employee, expressed excitement about the progress, highlighting the persistence required to bring a company like Starbucks to the negotiating table. She described it as a significant step forward.

John Logan, a labor studies professor, remains cautious about Starbucks’ intentions and whether they will truly commit to ending anti-union practices and reaching an initial contract.

The union representative for Starbucks, Michelle Eisen, remains optimistic about the future collaboration between Starbucks and the union, emphasizing the importance of valuing employee input for business success.

Starbucks has offered a settlement to the union following backlash over union-busting allegations, stock price declines, and disruptive strikes, showing a potential shift towards supporting unions.

Legal experts and union representatives see Starbucks’ possible unionization as a significant step that could inspire other companies to consider similar actions.

Overall, the announcement from Starbucks has far-reaching implications for workers’ rights and the future of unionization in major corporations.

Source: www.theguardian.com

New findings suggest that smoking may lead to an increase in unseen belly fat

When picturing a smoker, the image of a slender and stylish individual like Audrey Hepburn may come to mind. However, recent research indicates that even slim smokers could be harboring unhealthy fat hidden deep within their abdomens.

Despite the common belief that smoking can suppress appetite and the fear of weight gain upon quitting, a new study reveals that smokers are more likely to be underweight. Not only that but smokers also tend to accumulate more harmful deep abdominal fat, known as “visceral fat,” which is linked to increased risks of heart attack, diabetes, and dementia. This type of fat can be challenging to detect, leading to a false sense of fullness even with a flat stomach.


To investigate the relationship between lifelong smoking and belly fat, researchers at the University of Copenhagen utilized a statistical analysis tool called Mendelian randomization. This tool categorizes individuals based on their genetic information to identify causal connections between exposures like smoking and outcomes such as abdominal fat distribution.

The study involved analyzing genetic data from numerous studies on smoking habits and body fat distribution among individuals of European ancestry. By identifying specific genes associated with smoking behaviors and body fat distribution, the researchers were able to determine the impact of smoking on belly fat independent of other influencing factors like alcohol consumption and socio-economic background.

The lead author, Dr. Germán D. Carrasquilla, emphasized the importance of large-scale efforts to prevent and reduce smoking in light of their findings published in the journal Dependence. He believes that reducing smoking prevalence can indirectly decrease the prevalence of abdominal fat and ultimately improve public health outcomes.

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Source: www.sciencefocus.com

Microsoft Appoints DeepMind Co-founder to Lead Newly Formed AI Division

Microsoft has named the co-founder of the British artificial intelligence research institute DeepMind as the head of its new AI division. Mustafa Suleiman, now 39 years old, co-founded DeepMind with Demis Hassabis and Shane Legg back in 2010. The company was later acquired by Google in 2014 for £400m and has since become the core of Google’s AI efforts. Suleiman left DeepMind in 2019 and will now lead Microsoft AI, a new organization focusing on the US company’s consumer products and research. Several members from Suleiman’s Inflection AI startup will also join the division.

Microsoft has made a multibillion-dollar investment in OpenAI, the developer of the ChatGPT chatbot, to develop generative AI technology. Satya Nadella, Microsoft’s CEO, praised Suleiman as a visionary product maker and a team leader with a bold mission. The new division will integrate Microsoft’s consumer AI efforts, such as the Copilot chatbot and the Bing browser, which utilizes ChatGPT technology. Copilot is a key element in Microsoft’s AI monetization efforts, enabling users to easily compose emails, summarize documents, create presentations, and more.

Suleiman’s colleague Karen Simonyan, also a co-founder of Inflection AI, will join the new division as a principal investigator. Meanwhile, Bloomberg News reported that Apple is in talks to incorporate Google’s Gemini AI product into the iPhone. Inflection AI, backed by Microsoft and Nvidia, has become one of the leading companies in the generative AI race.

Suleiman, who has roots in both Syria and the UK, recently published a book on AI titled “The Coming Wave.” In it, he discusses both the potential benefits and risks of AI technology, calling for an increase in research on AI safety. In an interview last year, he described the book as a “provocation,” noting the importance of predicting future trends and taking action to mitigate potential risks.

Source: www.theguardian.com