The Unusual Connection Between Increased Rest and Enhanced Strength, Speed, and Health

Posted on November 1, 2025 by

Olympia Arnold Schwarzenegger has long emphasized the significance of sleep. “People grow when they sleep, not when they train,” he asserts. Professional athletes often adhere to meticulous sleep regimens tailored to their chronotypes (natural sleep-wake preferences) and synced with their training schedules.

For amateur athletes, the emphasis tends to be on nutrition and training protocols for optimal results. Elite coach Nick Littlehales was among the first to champion sleep as a crucial component of success, stating, “You can train as hard as you want, but without sleep, you can’t adapt. No adaptation means no progress.”

Let’s delve deeper into what occurs in your body during sleep and why it’s a vital aspect of your training regimen and performance strategy.

What occurs in your body during sleep?

Photo credit: Getty

Sleep is not merely a passive phase of training. When you exercise vigorously, your body engages in recovery during sleep. Deep (slow-wave) sleep enables your body to reset, repair, and regenerate. Cellular repair takes place as microtears from your workout are fixed through protein synthesis. If you’ve ever dealt with delayed onset muscle soreness (DOMS), you understand the significance of quality sleep for recovery.

During this sleep phase, human growth hormone (HGH) is released. The pituitary gland generates HGH, which facilitates muscle growth and healing. Furthermore, deep sleep enhances immune system function, reducing the risk of illness—an evident concern for anyone in the midst of a training routine.

What else is happening in our bodies while we sleep?

Glycogen levels are restored, and anti-inflammatory cytokines assist in muscle recovery.
Your heart rate decreases, blood pressure falls, allowing your cardiovascular system a chance to recuperate.
Quality sleep has been shown to enhance insulin sensitivity. Improved glucose metabolism boosts energy levels and aids body composition.
Sleep also regulates significant hormones like testosterone, which is crucial for endurance and recovery.

Brain recovery process during sleep

Not only does physical recovery occur during sleep, but mental rejuvenation takes place as well. During REM sleep, typically experienced in the latter half of the night, your brain engages in “housework,” organizing, filing, and tidying up. Motor memory consolidation reinforces neural pathways established during training. Did you execute the perfect tennis serve today? It’ll be etched in your mind tonight.

Additionally, emotional regulation contributes to managing stress, enhancing focus, and boosting motivation—key components for achieving peak performance.

Optimize your sleep quality

Swedish bed manufacturer Hästens recognizes the significance of quality sleep. This luxury brand has been handcrafting beds since 1852, with each piece meticulously created in the Swedish town of Köning and taking up to 600 hours to complete using only natural materials.

Hästens has launched the collaborative campaign “Sleep to Perform,” teaming up with champions from both creative fields and sports, including five-time Grand Slam champion Maria Sharapova. She acknowledges that success begins with prioritizing rest, stating, “No matter where you are in your career, sleep is vital for your performance. It’s not just about rest; it’s about being able to present the best version of yourself every day.”

To explore our full range of beds and accessories, and to discover the benefits of a restful night’s sleep, please visit: here.

To schedule a bed test at a sleep spa near you, use the following resources: www.hastens.com or contact your nearest authorized retailer.

Source: www.sciencefocus.com

Polls Reveal Increased Children’s Exposure to Pornography Since the 2023 Online Safety Act

Posted on August 19, 2025 by Igor Mitreski

Research conducted among English children has revealed a rise in exposure to pornography following the implementation of UK regulations intended to safeguard them online, with six-year-olds encountering it inadvertently.

Dame Rachel de Souza reported that the findings indicated an uptick in the number of young people encountering pornographic content before turning 18, even after the Online Safety Law came into effect.

Over a quarter (27%) admitted to having viewed porn online by the age of 11.

These results build on a similar survey carried out by the Children’s Commissioner in 2023, highlighting minimal progress despite newly instituted laws and commitments from government officials and tech companies.

She stated: “Violent pornography is readily accessible to children, often encountered accidentally via popular social media platforms, and has a profound impact on their behaviors and views.

“This report should signal a clear turning point. The fresh protections introduced in July by Ofcom, part of the Online Safety Act, present a genuine opportunity to prioritize child safety unequivocally in the online space.”

The findings stem from a representative national survey conducted in May with 1,010 children and young people aged 16-21, just prior to the implementation of the OFCOM child code in July.

The regulations set forth by Ofcom have brought significant changes designed to restrict access to pornographic websites for those under 18. Utilizing the same methodology and questions as in the 2023 survey ensures consistency:

A higher percentage of young people reported seeing porn before age 18 (70%) in 2025 compared to 2023 (64%).
More than a quarter (27%) acknowledged viewing porn online at age 11, with the average age of first exposure remaining at 13.
Vulnerable children, including those receiving free school lunches, children in social care, and those with special educational needs or disabilities, reported higher rates of exposure to online porn by age 11 compared to their peers.
Nearly half of the respondents (44%) agreed with the statement: “Girls might say no at first, but then they could be persuaded to have sex.” Further analysis showed that 54% of girls and 41% of boys who had viewed porn online resonated with this sentiment, in contrast to 46% of girls and 30% of boys who hadn’t.
A significant number of respondents indicated they encountered porn online accidentally rather than actively seeking it (35%). The rate of accidental exposure rose by 21 percentage points compared to 2023 (59% vs. 38%).
Social networking and media platforms constituted 80% of the primary sources of porn access for children, with X (formerly Twitter) being the most common portal, surpassing dedicated porn sites.
The disparity between the number of children viewing porn on X versus dedicated porn sites has widened (45% vs. 35% in 2025 compared to 41% vs. 37% in 2023).
Most respondents reported witnessing portrayals of actions which are illegal under existing pornography legislation or could be deemed illegal under forthcoming crimes and police bills.
Over half (58%) encountered pornographic content that depicted strangulation, with 44% observing sexual activity while individuals were asleep, and 36% witnessing instances where consent was not given or had been ignored.
Further scrutiny revealed that only a minority of children expressed a desire for violent or extreme content, indicating it is being made available to them.

The report highlights concerns that, even under current regulations, children may circumvent restrictions by utilizing virtual private networks (VPNs), which remain legal in the UK.

The report advocates for online porn to adhere to the same standards as offline porn, prohibiting depictions of non-fatal violence. It also calls for the Ministry of Education to equip schools to effectively implement new curricula on relationships, health, and sex education.

Recently, it was announced that traffic to the UK’s leading porn sites has drastically decreased following the strengthening of age verification measures. According to data analytics firm Simarweb, the popular adult site Pornhub saw a decline of over 1 million visitors within just two weeks.

Pornhub and other major adult platforms initiated enhanced age verification checks on July 25 after acknowledging that online safety laws should complicate access to explicit materials for individuals under 18.

Simarweb compared the average daily user statistics of porn sites from August 1 to 9 against the average from July, revealing that Pornhub, the UK’s top adult content site, experienced a 47% dip in domestic traffic on July 24, the day before the new regulations came into effect.

A government spokesperson remarked, “Children are growing up immersed in a digital landscape bombarded with pornography and harmful content, which can have damaging effects on their lives. Online safety laws are addressing this issue.”

“To be clear: VPNs are legitimate tools for adults, and there are no intentions to ban them. However, platforms promoting loopholes like VPNs to children could face stringent enforcement and hefty fines. We mustn’t prioritize business interests over child safety.”

Source: www.theguardian.com

Research Links Fried Foods to Increased Diabetes Risk

Posted on August 7, 2025 by Igor Mitreski

Craving some fries? Indulging in deep-fried delights might raise your chances of developing type 2 diabetes.

As per research released on Wednesday in the Journal BMJ, swapping out weekly servings of fries for boiled, baked, or mashed potatoes could diminish the risk of this chronic illness.

The study analyzed the eating habits of over 205,000 adults in the U.S. who completed a dietary survey spanning nearly 40 years. They investigated the correlation between potato consumption and the onset of type 2 diabetes.

Results indicated that a weekly intake of French fries raised the risk of type 2 diabetes by 20%. In contrast, consuming an equivalent amount of boiled, baked, or mashed potatoes showed no association with the disease.

According to the CDC, one in ten Americans with diabetes has type 2. This condition can lead to elevated risks of heart attacks, strokes, and kidney damage.

The findings emphasize the importance of food preparation methods in determining health risks and benefits, noted Seyed Mohammad Mousavi, the lead author of the study and a postdoctoral researcher at the Harvard Chan School of Public Health.

“Not all potatoes are created equal,” he remarked. “Even consuming less than one serving of fries weekly can elevate the risk of type 2 diabetes.”

Unlike boiled or baked potatoes, fries are often cooked in oils high in trans fats or saturated fats. The body struggles to properly metabolize these fats, leading to insulin resistance—an issue that regulates blood sugar levels. Frequent consumption of fried foods can contribute to obesity and inflammation, further increasing the likelihood of type 2 diabetes.

“Fried potatoes absorb fat, raising their caloric content. Consuming multiple servings of fries can contribute to weight gain,” stated Candida Rebello, director of the Nutrition and Chronic Disease Program at Louisiana State University, who was not part of the study.

This research leveraged data collected when various frying methods were prevalent from 1984 to 2021. Nowadays, most fast-food chains utilize vegetable oils like canola, sunflower, soybean, and peanut oils. However, beef fat was common in the 1980s, which shifted to partially hydrogenated oils in the early 1990s. Most trans fats have been phased out of the U.S. diet by 2018.

Secretary of Health and Human Services, Robert F. Kennedy Jr., claimed that the seed oils in use today contribute to rising obesity levels in children, suggesting a return to beef fat—a stance lacking robust scientific backing.

“Beef tallow is rich in saturated fats, which can be harmful. I do not endorse that,” Mousavi emphasized.

One drawback of Mousavi’s study is that it doesn’t account for added unhealthy ingredients in boiled, baked, or mashed potatoes.

“What do people put on baked potatoes? Butter, bacon, cheese, sour cream,” said Shannon Gallien, an assistant professor of nutrition science at Texas Institute of Technology. “We don’t know if they consumed the skin either.”

Gallien noted that potato skins are rich in fiber and essential nutrients, helping regulate blood sugar. When prepared without deep frying or excessive fats, potatoes can provide a good source of potassium, which supports blood pressure regulation.

“Certainly, potatoes can be a nutritious food choice as long as they are neither fried nor smothered in fat,” Gallien stated.

Mousavi suggested that baking fries at home with healthier oils like olive or avocado oil could lower diabetes risk compared to fast food versions. Opting for whole grains, such as farro or whole-grain bread and pasta, could yield even greater benefits due to their lower glycemic index, reducing the likelihood of rapid blood sugar spikes.

His research found whole grains pose a lesser risk of diabetes than all potato varieties. Conversely, white rice correlated more strongly with the risk of type 2 diabetes than any of these alternatives.

Megan Marcahai, communications director at Potato USA, emphasized that fries can “fit into a healthful dietary framework when consumed in moderation.”

Gallien highlighted the importance of evaluating one’s overall diet, since it significantly impacts health more than single food items. Nutritionists generally endorse a colorful array of foods, incorporating healthy proteins, varied fruits, vegetables, whole grains, fish, beans, and nuts.

“People don’t eat isolated items. They consume a range of foods,” Gallien concluded.

Source: www.nbcnews.com

Alert: Increased Threat of Submarine Cable Attacks Supported by Russia and China

Posted on July 17, 2025 by Igor Mitreski

Recent reports indicate an increasing risk of assaults on submarine cables supported by Russia and China, which facilitate international internet traffic, particularly amid ongoing tensions in the Baltic Sea and Taiwan.

Submarine cables represent 99% of global intercontinental data traffic and have experienced various disruptive incidents allegedly tied to state activities in the past 18 months.

A study conducted by the US cybersecurity firm Recorded Future has highlighted nine incidents expected in the Baltic Sea and near Taiwan in 2024 and 2025, suggesting a predictive pattern for further harmful actions.

According to the analysis, while genuine accidents could lead to damage to many submarine cables, the situations in the Baltic Sea and Taiwan suggest a rise in malicious actions attributed to Russia and China.

“The operations linked to Russia in the Baltic region and China in the Western Pacific are likely to increase as tensions elevate,” the firm noted.

The report points to several incidents, including the disconnection of two submarine cables from Lithuania to Sweden in November, with accusations directed at an anchor dragged by a Chinese vessel. Also in December, a Russian oil tanker was detained after severing cables between Finland and Estonia.

In Taiwan, recent incidents include cable damage caused by a Chinese-operated cargo vessel zigzagging over the line to Peng Island in February. One month prior, another Chinese vessel was suggested as a likely source of damage to the Taiwan-US cable.

The analysis states, “While deterring state-sponsored sabotage linked to the Baltic and Taiwan incidents is challenging, such activities align with the strategic goals of Russia and China, as well as observed operations and their existing deep-sea capabilities.”

Recorded Future emphasizes that successful attacks on multiple cables are likely to result in prolonged disruptions, typically requiring intervention in deeper waters and likely involving state-level threat actors due to the complexities of accessing these sites. Such actions may occur prior to a full-scale conflict, the report suggests.

The firm noted 44 distinct cable damages have been recorded over the past 18 months. A significant portion is attributed to “unclear causes,” while nearly a third remains unexplained, with 16% due to seismic activity or other natural events.

Submarine cables installed in the Baltic Sea. Analysts suggest sabotaging these cables is a strategic move, as it can be framed as accidental damage. Photo: Lehtikuva/Reuters

Analysts believe that targeting subsea cables presents a strategic advantage, as such actions can disguise as accidental damage or implicate vessels without direct connections to any suspected attackers.

To mitigate the risk of incidents damaging multiple cables and resulting in “long-term connectivity issues,” Recorded Future recommends enhanced cable monitoring, improved security measures, and robust stress testing of subsea infrastructure.

Notably, despite incidents in the Baltic and Taiwan regions, the most severe cases unfolded elsewhere. In February last year, a missile from Houthi forces struck a ship’s anchor, severely disrupting communications in the Middle East. A month later, in West Africa, an underwater landslide caused significant issues, followed by another critical incident off the coast of South Africa in May 2024 related to cable drifting.

The implications of the Red Sea and African incidents reveal that the longest-lasting disruptions occur in regions with limited alternative cable options and insufficient repair capabilities, irrespective of the specific causes.

In contrast, two cable incidents in the Baltic Sea last November had minimal repercussions due to their relatively low impact and the resilience of European internet infrastructure. However, the report highlights that three EU island nations—Malta, Cyprus, and Ireland—are more susceptible due to their heavy dependence on submarine cables for global communications.

The recent strategic defense assessment from the UK government acknowledged the potential threats to submarine cables and recommended a greater and more coordinated role for the Royal Navy in safeguarding the submarine infrastructure that carries vital information, energy, and goods relied upon by citizens.

Source: www.theguardian.com

Nightmares Linked to Accelerated Biological Aging and Increased Mortality Risk

Posted on June 23, 2025 by Igor Mitreski

Strategies to Prevent Nightmares, Such as Avoiding Scary Movies

Andrii Lysenko/Getty Images

Experiencing nightmares weekly may accelerate aging and significantly increase the chances of early death.

“Individuals with more frequent nightmares experience faster aging and a higher risk of premature death,” states Abidemi Otaiku from Imperial College London.

In collaboration with his team, Otaiku examined data from over 183,000 adults aged between 26 to 86 who participated in several studies, initially self-reporting their nightmare frequency over a span of 1.5 to 19 years.

The findings revealed that individuals reporting weekly nightmares are over three times more likely to die before reaching 70 compared to those who do not experience nightmares.

Moreover, the researchers noted that the frequency of nightmares is a more potent predictor of preterm birth than factors such as smoking, obesity, poor diet, or inadequate physical activity. Otaiku presented these findings at the European Neurological Society Conference 2025 held in Helsinki, Finland, on June 23rd.

The team additionally assessed participants’ biological ages by measuring telomere lengths, small DNA sequences at the ends of chromosomes that shorten with each cell division; short telomeres linked to premature aging. This segment of the study also included approximately 2,400 children aged 8 to 10, while adults contributed further biological age data using epigenetic clocks.

According to Otaiku, their research established a consistent connection between frequent nightmares and accelerated aging across various ages, genders, and ethnic backgrounds. “Even in childhood, those with frequent nightmares exhibit shorter telomeres, indicating faster cellular aging,” he remarked. In adults, this accelerated biological aging accounts for roughly 40% of their heightened risk of death.

Regarding the reasoning behind this association, Otaiku suggests two main factors. The first is the elevated levels of the stress hormone cortisol triggered by nightmares. These levels are linked to faster cellular aging. “Nightmares elicit a more intense stress response than what is typically experienced upon waking, often rousing us with pounding hearts,” he explained.

The second factor involves sleep disruption, which hinders the body’s overnight cellular repair processes. Poor sleep quality is associated with an increased risk of various health issues, including heart disease.

For those wishing to reduce their occurrence of nightmares, Otaiku suggests straightforward strategies, such as avoiding scary movies and addressing mental health issues like anxiety.

“This is a fascinating finding with a number of biological underpinnings,” said Guy Restiner from the NHS Foundation Trust at Guy and St. Thomas. However, he emphasized that further research is necessary to identify causal relationships, noting that nightmares can be associated with various medical conditions and medications that may impact the findings as individuals age.

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Source: www.newscientist.com

Scientists Discover Genetic Variations Linked to Increased Cat Pairing

Posted on June 3, 2025 by Igor Mitreski

Cat (Ferris Katas) has become a beloved companion to people worldwide. Despite its widespread popularity, the genetic factors influencing its behavior have been largely unexplored. A new research team from the Kyoto University Wildlife Research Center has focused on the Androgen receptor gene (ar), located on the X chromosome, and its association with feline behaviors, such as purring.

Okamoto et al. found that male cats with short alleles displayed higher directional call/voicing scores, whereas females with short alleles exhibited increased aggression towards strangers compared to their counterparts with long alleles. Image credit: Natary Anderson.

“Cats are cherished companion animals that significantly contribute to society through their interactions with humans,” said lead author Okamoto and colleagues.

“However, most negrid species, such as the African Wildcat (Ferris Livica), have solitary ancestors, while domestic cats often form groups and display social behaviors.”

“They communicate with both humans and other cats utilizing a range of behaviors and signals, including olfactory cues, touch, visual cues, and vocalizations.”

“Purring, a distinctive vocalization of cats, plays a significant role in vocal communication.”

“Initially, purring may signify a mother’s health, but it continues to facilitate communication among cats beyond the weaning phase.”

“In a social context, purring promotes security and comfort, expresses familiarity, and invites play, though its precise function remains unclear.”

For this study, researchers evaluated the behavior of 280 cats, all of whom were neutered or mixed breeds living in their owners’ homes.

DNA samples were collected and analyzed to compare the ar gene with those from other negrid species.

“Upon reaching out to participants, we quickly received responses and warm messages from 265 cat owners across Japan within just a day,” Okamoto remarked.

“This highlighted the strong public interest in feline research.”

“The findings suggest a genetic basis for both purring and vocal communication.”

“Cats with the short-type androgen receptor gene received higher ratings from their owners than those with the long-type gene.”

“Additionally, male cats with the short form displayed increased vocalizations towards humans, indicating a genetic link to vocal communication.”

“Conversely, female cats with the shorter-type gene demonstrated heightened aggression towards unfamiliar individuals.”

“These findings could indicate a decreased significance of vocal communication in cats raised by humans from kittenhood, particularly those that are typically purebred.”

“Prior studies indicated that purebred cats are more likely to carry long-form genes than their mixed-breed counterparts.”

“This study included numerous mixed-breed cats that were rescued and were previously strays.”

Through comparisons of cat genes with 11 other genes, researchers discovered that both leopard and fishing cats were genetically similar to domestic cats and possessed shorter types, while domestic cats did not exhibit longer types found in other species.

These results imply that the emergence of long types may be linked to genetic changes related to domestication and selective breeding.

“These results may help predict behavioral trends based on genetic data, enhance observation and care based on needs, and ultimately improve animal welfare,” the authors stated.

The team plans to broaden their research focus to include other negrid species.

“Through our research, we aim to enrich our understanding of cats and foster better relationships between felines and humans,” Okamoto concluded.

This study was published online on May 28th in PLOS 1.

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Y. Okamoto et al. 2025. The relationship between androgen receptor genes and cat behavioral traits (Ferris Katas). PLOS 1 20(5): E0324055; doi: 10.1371/journal.pone.0324055

This article is based on an original release by Kyoto University.

Source: www.sci.news

Trump Advocates for Increased Birth Rates but Dismisses Fertility Experts

Posted on May 8, 2025 by Igor Mitreski

Every year, tens of thousands of young women opt to freeze their eggs. This procedure can be costly and at times painful, with numbers rising as more Americans delay childbirth.

However, many uncertainties surround the process: What is the optimal donor age for egg freezing? What are the success rates? And importantly, how long can frozen eggs remain viable?

Finding reliable answers to these questions is challenging. During the significant downsizing at the Centers for Disease Control and Prevention, the Trump administration disbanded a federal research team dedicated to collecting and analyzing data from fertility clinics aimed at enhancing outcomes.

According to Aaron Levine, a professor at Georgia Tech’s Jimmy and Rosalyn Carter School of Public Policy, who collaborated with the CDC team on research, the dismissal of the six team members was “a real, serious loss.”

“They held the most extensive data on fertility clinics, focused on ensuring truthfulness in patient advertising,” stated Barbara Collura, CEO of the National Infertility Association.

Collura emphasized that losing the CDC team is a significant blow to both couples facing infertility and women contemplating egg freezing.

These layoffs come amidst rising political interest in declining U.S. fertility rates. President Trump has dubbed himself the “infertile president” and signed an executive order aimed at expanding access to in vitro fertilization.

“The White House is committed to IVF and remains focused on it,” Collura noted.

With one in seven married or unmarried women experiencing infertility, she remarked, “Looking at these statistics, it’s disheartening—and not surprising—that our public health agencies have chosen to sidestep this issue.”

When asked about the team’s elimination, a health and welfare spokesperson commented that the administration is “in the planning stage” of transitioning maternal health programs to a new Healthy America initiative, offering no further details.

The scientists from the National Assisted Reproductive Technology Surveillance System were working to address numerous questions surrounding IVF research.

“We lack comprehensive data on the success rates of egg freezing for personal use because it’s relatively new and tricky to track,” Dr. Levine explained.

This uncertainty weighs heavily on women wishing to have children. Simeonne Bookal, who collaborates with Collura at Resolve, froze her eggs in 2018 while waiting to find the right partner.

She got engaged earlier this year, with her wedding scheduled for next spring. At 38, she expressed that having her eggs banked offers her a “security blanket.”

Though she still has reservations about her chances of conceiving, the frozen eggs provide her some assurance.

The precise success rate of the egg freezing procedure remains ambiguous, as many published studies are based on theoretical models that utilize data from infertile patients or egg donors, which differ significantly from women preserving their eggs for future use.

Some studies provide limited insights, often involving fewer than 1,000 women who thaw their eggs and undergo IVF, according to Dr. Sarah Druckenmiller Cascante, a Clinical Assistant Professor of Obstetrics and Gynecology at Nyu Langone and author of a recent review paper on this topic.

“The available data is scant, and it’s crucial to be transparent with patients about this,” she said.

“I wouldn’t regard it as a guaranteed insurance policy. While it could lead to a baby, it’s more about improving the chances of having a biological child later in life, especially if done at a younger age.”

The CDC team maintained a database known as the National ART Surveillance System, established by Congress in 1992. This tracked success rates for various fertility clinics but now faces an uncertain future without continuous updates.

While the Society for Assisted Reproductive Technology offers similar databases to researchers, they are not as comprehensive as the CDC’s since they contain data from approximately 85% of U.S. fertility clinics.

According to Sean Tipton, Chief Advocacy and Policy Officer for the American Association of Reproductive Medicine, no dedicated research team oversees the database.

The surge in women opting to bank their eggs for future use has intensified the scrutiny regarding the risks and benefits of freezing eggs.

This procedure was regarded as non-experimental as of 2012. In 2014, only 6,090 patients opted to bank their eggs for fertility preservation. Fast forward to 2022, and that number soared to 28,207, with 39,269 recorded in 2023, the latest year for which data is available.

Source: www.nytimes.com

Research shows that elderly individuals are seeking care for cannabis use due to increased risk of dementia.

Posted on April 15, 2025 by Igor Mitreski

Hospital or emergency room care for cannabis use among middle-aged and elderly individuals may lead to an increased risk of developing dementia, according to a large Canadian study published in Jama Neurology. Over a five-year period, individuals seeking care for cannabis use were almost twice as likely to develop dementia compared to the general population.

The study, which analyzed medical records of six million Ontario residents from 2008 to 2021, highlighted a 23% higher risk of dementia among cannabis users compared to those seeking care for other reasons.

While the study did not specify the amount of cannabis used by participants, it did not establish a causal relationship between regular or heavy cannabis use and dementia.

Dr. Daniel T. Myran, the study’s lead author, emphasized the need for further research to explore the potential link between cannabis use and dementia. He acknowledged the complexity of determining whether cannabis use could lead to dementia and highlighted the importance of addressing these concerns.

Previous research by Dr. Myran indicated a higher mortality rate among individuals with cannabis use disorder and noted an increase in cases of schizophrenia and psychosis related to cannabis use in Canada.

Recent studies focusing on the impact of cannabis use on cognition have provided valuable insights, highlighting potential risks associated with regular or heavy cannabis consumption.

While previous research on cannabis and dementia has been limited, the strength of the new study lies in its large sample size and long-term follow-up of patients. Dr. Madeline Meyer, an expert not involved in the study, commended the study for its ability to rule out dementia at the outset and track the temporal relationship between cannabis use and dementia.

Dr. Meyer’s own research has linked cannabis use with neuropsychological decline, challenging the perception of cannabis as a harmless substance with potential medical benefits.

She emphasized the importance of taking the association between cannabis use and dementia seriously and considering the potential risks it may pose.

The increasing use of cannabis among older adults has raised concerns about potential health risks, including the development of dementia. A new study found a significant rise in cannabis-related medical visits among adults aged 45 and older, prompting further investigation into the potential impact of cannabis on cognitive health.

Comparing individuals with cannabis-related medical visits to the general population, the study highlighted a higher incidence of dementia among cannabis users, emphasizing the need for comprehensive evaluation of the risks associated with cannabis use.

While some factors contributing to the increased risk of dementia among cannabis users can be explained, others remain unclear, requiring further research to fully understand the potential relationship between cannabis use and cognitive decline.

Dr. Mylan and his colleagues found that individuals seeking care for alcohol use are more likely to be diagnosed with dementia than those using cannabis, highlighting the complex nature of substance use and its impact on cognitive health.

Despite efforts to control for various factors, there are still uncertainties surrounding the potential link between cannabis use and dementia. It is essential to consider all possible variables that may contribute to the development of dementia in cannabis users.

Source: www.nytimes.com

The Increased Importance of Exercise with Weight Loss Medication

Posted on March 26, 2025 by Igor Mitreski

For decades, traditional wisdom has believed that in order to lose weight, you have to eat less and move more. Of course, that’s easier said than done. That’s why drugs like Wegovy are so innovative. By suppressing appetite, they help to tackle the first part of the equation, which usually leads to dramatic weight loss. But what about the second one? If weight loss pills are reducing the number of scales, should we still head to the gym? And how do these drugs affect our athletic ability?

What has become clear is that it may be even more important for those taking these medications than those who don’t. The ability of semaglutide to induce rapid weight loss (see “How do they work?” below) also leads to a significant decrease in muscle mass. For example, a 2021 study of 95 people who were overweight or obese taking semaglutide found that their lean body mass was reduced by almost 10% on average, 68 weeks later.

This article is part of a special series investigating the GLP-1 agonist boom. Click here for details.

Lean body weight covers body tissues such as muscles and bones. Therefore, these results suggest that both are affected when taking weight loss medications, Signee Sørensen Torekov at the University of Copenhagen explains. These drugs guide people to burn fewer calories, so the body needs to break down fat, muscle, and even bones for nutrients.

“Our understanding is that up to about 40% of the overall weight loss seen in semaglutide is thought to be due to the loss of muscle mass,” he said.

Source: www.newscientist.com

Night Owls Beware: Increased Risk of Depression Identified

Posted on March 20, 2025 by Igor Mitreski

Early risers catch worms, but night owls are more susceptible to depression. A recent study suggests that individuals who prefer staying up late are more likely to experience depressive symptoms.

Research conducted by the University of Surrey reveals that this could be due to the fact that night owls often struggle with poor sleep, exhibit lower levels of mindfulness, and tend to consume more alcohol compared to early birds.

“Late chronotype, also known as ‘eveningness’ or ‘night owl,’ refers to a biological inclination to be active in the evenings and have a later sleep-wake pattern,” explained Cognitive Neuroscience Lecturer Dr. Simon Evans, who led the study, as reported by BBC Science Focus. “Since chronotypes have a genetic basis, being a night owl is a natural biological predisposition.”

Evans and his team surveyed 564 university students on their sleep habits, mindfulness levels, alcohol consumption, as well as their levels of depression and anxiety, which reflect tendencies towards negative thinking about situations and events.

“Late chronotypes are particularly prevalent among young adults, with up to 50% of young adults falling into this category,” noted Evans. “This is concerning as delayed chronotypes are associated with a higher risk of depression, anxiety, and substance use.”

The study confirmed that night owls were significantly more prone to developing depression than early birds and reported higher levels of anxiety.

Students with later chronotypes reported poorer sleep quality compared to early risers, which researchers attributed to “social jet lag.”

“Being a night owl is common among young adults,” said Evans. “Given the importance of mental health in youth, work and educational schedules should accommodate night owls for improved sleep.”

Our preference for morning or evening routines is largely influenced by genetics, with younger adults more likely to prefer later schedules, while older adults tend to be early risers. – Credit: rawpixel via Getty

Furthermore, individuals with a delayed chronotype tended to consume more alcohol, a known risk factor for depression. However, the study did not find a direct association between alcohol consumption and depression among the students involved.

In fact, night owls who consumed alcohol were less likely to experience depression than non-drinkers, although most students consumed alcohol in moderation. Researchers suggest that the social connections formed during drinking may offset the negative effects.

Evans also recommended strategies for night owls to protect themselves from depression, including promoting mindfulness through practices like guided meditation, focusing on improving sleep quality, and reducing alcohol consumption.

This study was recently published in the scientific journal PLOS 1.

Read more:

About our experts:

Dr. Simon Evans is a senior lecturer in cognitive neuroscience at the Faculty of Psychology, University of Surrey. He obtained his PhD from the Institute of Neurology, University College London in 2011 and conducted postdoctoral training at the University of Sussex, where he used MRI techniques to study how genetic factors impact brain activity patterns and cognitive performance. Evans’ primary research interest lies in utilizing brain imaging techniques to explore cognitive changes across the lifespan.

Source: www.sciencefocus.com

Plans for Increased Surveillance by ICE Contractors During Trump’s Immigration Crackdown | Technology

Posted on February 28, 2025 by Igor Mitreski

GEO Group, the largest single private contractor for U.S. Immigration Customs Enforcement (ICE), has expanded its surveillance operations to monitor hundreds of thousands or potentially millions of migrants.

Geo Group, a private prison company and parent company of Bi Inc, has been working with ICE for nearly two decades to oversee the agency’s electronic surveillance program. Currently, they are tracking approximately 186,000 immigrants using various devices like ankle monitors, smartwatches, and facial recognition apps, as reported by Public Ice Data. With the increasing demand from the administration of Donald Trump, which has promised significant deportations, company executives anticipate that this number will surpass the previous peak of 370,000 to 450,000 immigrants within the next year. This statement was made during the company’s fourth-quarter revenue call on Thursday morning.

“About two years ago, ISAP contract utilization peaked at around 370,000,” mentioned George Zorry, executive chair of GEO Group, during a revenue call discussing the ICE and GEO contract. “If the contract exceeds its previous peak usage, achieving revenues of $250 million is possible.”

The company is ramping up the production of additional GPS units in preparation for expanded ICE contracts. Executives suggest they can monitor “hundreds of thousands” of individuals and are positioning themselves to monitor even more, potentially reaching into the millions. Zoley mentioned that GEO Group and its competitor, Core Civic, will engage in conversations with ICE to expand current contracts and electronic monitoring for detention facilities.

“It’s a dynamic situation, rapidly evolving,” he stated. “We’ve shifted from initial proposals to detailed pricing and operational discussions. The procurement process is moving at an unprecedented pace. I’ve never seen anything like it.”

Established in 2004 as an alternative to detention, the company’s extensive electronic surveillance program has been entrusted to Bi Inc, a subsidiary of Geo Group. Many individuals wearing ankle monitors raised concerns about overheating, discomfort, or tightness. The company has introduced SmartLink, a Smart Watch location tracker, and a smartphone app as less intrusive monitoring methods. However, during the revenue call on Thursday, executives expressed a desire to return to relying primarily on ankle monitors.

“Our top priority is ankle monitors for high-security monitoring,” Zoley emphasized.

While the company has not received indication from ICE about reissuing a new agreement for their electronic monitoring program, the executive team is focusing on expanding the number of individuals tracked through existing programs. Geo Group plans to invest $16 million to increase federal ISAP use and build up Ankle Monitor inventory to cater to hundreds of thousands and potentially millions of participants.

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Company officials believe that under the Laken Riley Act, immigrants charged with violent crimes or thefts must be monitored “indefinitely” under the ISAP program due to the risk they pose. Executives intend to expand the surveillance program to monitor an estimated 7-8 million individuals with non-decisive immigration statuses who entered the US through unauthorized routes. They are also preparing to monitor an estimated 95-100 million people in the United States.

“Given our population size, we view this as an opportunity to enhance detention capacity… The Laken Riley Act mandates a significant increase in electronic monitoring services to combat human trafficking involving individuals with non-decisive immigration statuses and ensure compliance with immigration court requirements,” Zoley stated.

Source: www.theguardian.com

Common Painkillers During Pregnancy Linked to Increased Risk of ADHD in Children

Posted on February 13, 2025 by Igor Mitreski

Microscopic view of paracetamol crystals

Henri Koskinen/Shutterstock

Children who used paracetamol, also known as acetaminophen, during their mother’s pregnancy, are more likely to develop ADHD than those whose mothers do not, suggesting small studies. Although inconclusive, this finding gives weight to the contested idea that widely used painkillers can affect fetal brain development.

Previous studies on paracetamol and neurodevelopmental conditions provide conflicting findings. For example, a 2019 study linking over 4,700 children and their mothers with their mothers to use painkillers during pregnancy There is a 20% higher risk Children developing ADHD. However, the analysis presented by nearly 2.5 million children last year There is no such connection When comparing siblings who were exposed or not to paracetamol before birth.

One problem is that most of these studies rely on self-reported medication use. This is a serious limitation as you may not remember taking paracetamol during pregnancy. For example, only 7% of participants in the 2019 study reported using paracetamol during pregnancy. It's well below the 50% seen in other studies. “A lot of people take it [paracetamol] Without knowing that” Brennan Baker At Washington University in Seattle. “It could be the active ingredient in some of the cold medicines you're using, and you don't necessarily know.”

So Baker and his colleagues used more accurate metrics instead. They looked for medication markers in blood samples collected from 307 women. They were all black and lived in Tennessee in the late pregnancy. None of them were taking medication due to chronic illnesses and were unaware of the complications of pregnancy. The researchers then followed up with participants when the child was 8 to 10 years old. In the US, Approximately 8% of children I have ADHD between the ages of 5 and 11.

On average, children whose mothers had a marker of paracetamol in their blood were three times more likely than children born to mothers, even after adjusting for factors such as mother's age and body mass index before pregnancy. There was a possibility (BMI), mental health status among close relatives of socioeconomic status and mental health. This suggests that using paracetamol during pregnancy may increase the risk of developing ADHD in children.

However, it is also possible that the actual factor that increases your risk of ADHD is not the drug itself, but the first thing you will be taking paracetamol. “They couldn't explain anything like the reason why their mother took it. [paracetamol]”It has been found to be risk factors for adverse development in children, such as headaches, fever, pain and infectious diseases.” Viktor Ahlqvist At the Karolinska Institute in Sweden.

But Baker believes that it is the drugs that are responsible. Subsequent analysis of tissue samples from 174 of participants' placenta showed that people using paracetamol have different metabolic and immune system changes. These changes are similar to those seen in studies testing the effects of paracetamol in pregnant animals without infection or underlying health conditions.

“I think the fact that we see immune upregulation in animal models also really strengthens the causal case,” Baker says. “There are many previous studies showing that elevated immune activation during pregnancy is linked to adverse neurodevelopment.”

Yet these findings are far from conclusive. For one thing, the study included a small number of participants, all black and lived in the same city, limiting the generalization of the findings. Another case, it measured only the blood markers of paracetamol at one moment. These markers have stuck for about three days, so the study probably captured more frequent users, and may have a dose-dependent effect, says Baker.

“[Paracetamol] Now is the first-line treatment option for pain and fever during pregnancy,” says Baker. “But I think I'm an agency [US Food and Drug Administration] In addition, various obstetric and gynecological associations should continuously review all available research and update their guidance. ”

Meanwhile, if it's unclear whether to take paracetamol during pregnancy, people should talk to their doctor, Baker says.

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Source: www.newscientist.com

Microsoft’s increased collaboration with Israeli military during Gaza conflict exposed

Posted on January 23, 2025 by Igor Mitreski

The documents exposing the Israeli military’s increased reliance on Microsoft’s cloud technology and artificial intelligence systems during the peak of the bombing of Gaza have been leaked.

From October 7, 2023, Microsoft will enhance its partnership with Israel’s defense agencies by providing better computing and storage services along with technical support hours worth at least $10 million. This deal was signed in a move to deepen collaboration with the IDF.

A joint investigation by The Guardian, +972 Magazine, and Local Call, based on documents from Drop Site News, unveils Microsoft’s deep connections with the Israeli military, especially during the Gaza offensive in 2023.

The Israeli Defense Forces increasingly turned to large U.S. tech companies like Microsoft, Amazon, and Google to meet their technological needs during the conflict.

Palestinians walk through destruction caused by Israeli air and ground attacks in Rafah, Gaza Strip, early 2025. Photo: Mohammad Abu Samra/AP

Leaked documents reveal that Microsoft’s products, mainly Azure cloud computing, are extensively used by various Israeli military units and intelligence agencies.

Microsoft’s involvement in highly sensitive and top-secret projects for the Israeli Ministry of Defense underscores the deep partnership between the company and the IDF.

While Microsoft has declined to comment on the revelations, the Israeli military’s increased use of AI-based services from tech giants like Microsoft during the conflict has raised concerns about the blending of civilian and military digital infrastructure.

Israeli soldiers prepare to launch a military drone at an undisclosed location near Israel’s southern border with the Gaza Strip in January 2024. Photo: Atef Safadi/EPA

The integration of Microsoft’s cloud and AI technologies into IDF operations has facilitated data analysis and storage for intelligence and combat purposes.

Microsoft’s extended partnership with the Israeli military, despite public scrutiny, highlights the ongoing collaboration between tech giants and defense agencies in modern warfare.

Source: www.theguardian.com

Increased power outages likely to expand nationwide in the U.S.

Posted on January 23, 2025 by Igor Mitreski

A new report predicts that power outages lasting more than eight hours will increase in the United States in the coming years due to climate change. Extreme weather events caused by climate change, such as cyclones, are making it challenging to cope with these outages. Severe weather events that occur simultaneously, like wildfires during heat waves, are already causing more prolonged power outages, according to a study published in the journal agreement.

From 2000 to 2023, 80% of power outages in the US were weather-related, and this number is expected to rise further due to the increasing severity and frequency of extreme weather events accelerated by climate change. These events not only come with economic costs but also health risks, disrupting essential services like heating, air conditioning, and medical equipment.

https://c02.purpledshub.com/uploads/sites/41/2025/01/GettyImages-2193374564.mp4

More than 400,000 homes and businesses in California lost power due to recent devastating wildfires

While it may not be possible to prevent weather events, researchers believe that tracking patterns can help in better preparing for power outages and distributing aid effectively. Understanding when and where power outages coincide with severe weather events can help mitigate their impact, particularly as aging power grids and climate change lead to more severe weather.

A study analyzed weather events from 2018 to 2020, finding that nearly 75% of US counties experienced significant power outages during dangerous weather events. The study also observed an increase in simultaneous power outages and wildfires along the West Coast from 2018 to 2020.

Researchers are now working on simulating different dangerous weather combinations in various regions to develop effective response plans across the country. Doctoral student and lead author of the study, Vivian Do, emphasized the importance of understanding these patterns to minimize the societal impact of power outages during severe weather events.

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Source: www.sciencefocus.com

Research Shows Individuals with Increased Emotional Intelligence Have a Greater Propensity to Use Emojis

Posted on December 6, 2024 by Igor Mitreski

According to a new study, higher emotional intelligence is linked to increased emoji use with friends, while avoidant attachment is linked to decreased emoji use with friends, dates, and romantic partners.

The frequency of emoji usage varies by gender and type of relationship. Image credit: Pete Linforth.

Emoji are characters that depict emotions, objects, animals, etc.

Sending alone or with text via computer or smartphone can create more complex meanings during virtual communication.

Assessing how emoji use varies as a function of communication and interpersonal skills provides insight into who uses emoji and the psychological mechanisms underlying computer-mediated communication.

Despite the widespread use of emojis in our daily social lives, little is known about who uses them, apart from evidence of differences related to gender and personality traits.

To fill this knowledge gap, Dr. Simon Dube of the Kinsey Institute and his colleagues surveyed a sample of 320 adults to determine their emotional intelligence across emoji usage, attachment style, and gender and relationship type.

Emotional intelligence is the ability to process and manage your own and others’ emotions. Attachment style refers to the pattern of how an individual interacts with others in intimate relationships, influenced by early interactions with primary caregivers.

These styles are divided into three main types: anxious, avoidant, and secure attachment.

Both anxious and avoidant attachment styles indicate that a child does not feel secure with their primary caregiver.

In contrast, children with a secure attachment style tend to be enthusiastic when reunited with their caregivers after a short period of separation.

The results revealed that people with higher emotional intelligence and secure attachment may use emojis more frequently.

For women, higher levels of attachment avoidance were associated with lower frequency of sending and receiving emojis with friends, partners, and romantic partners.

For men, higher levels of attachment avoidance were associated with sending fewer emojis to such partners.

Additionally, women used more emojis than men, but this difference was specific to interactions with friends and family.

One limitation of this study is that most of the participants were white, educated, married, English-speaking, heterosexual, living in the United States at the time.

However, the authors say the study opens up new research avenues at the intersection of psychology, computer-mediated communication, and the study of attachment and emotional intelligence.

The researchers state, “How we interact during virtual communication may reveal something more about ourselves.”

“It’s more than just a smiley face or a heart emoji. It’s a way to convey meaning and communicate more effectively, and how you use it can tell us something about you.”

a paper Survey results will be published in a magazine PLoS ONE.

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S. Dube others. 2024. Beyond words: The relationship between emoji use, attachment style, and emotional intelligence. PLoS ONE 19 (12): e0308880;doi: 10.1371/journal.pone.0308880

Source: www.sci.news

Report finds that Hurricane Helen had increased rainfall and stronger winds as a result of climate change

Posted on October 9, 2024 by Igor Mitreski

Samamuri

Climate change has increased Hurricane Helen’s wind speed by 11% and total precipitation by about 10%, according to a new report.
Researchers expect Milton to do the same, and say it is likely to get worse because of climate change.
The report says the higher sea surface temperatures that contributed to the intensification of both storms are 200 to 500 times more likely to be due to climate change.

As Hurricane Milton hurtles toward Florida’s west coast, a new report estimates how intense Hurricane Helen’s winds and rain could have been due to climate change. Scientists involved in the study said they expected Milton to do the same, and that it would likely get worse because of climate change.

The report, released late Wednesday night, is from the World Weather Attribution Group, a consortium of scientists that analyzes extreme weather events and determines how much climate change has influenced certain events. He is regarded as the leading expert in making decisions.

The findings show that because of climate change, Hurricane Helen’s wind speeds were 11% more intense and its precipitation totals were about 10% higher.

Friederike Otto, a climate scientist at Imperial College London who contributed to the new study, said “we now have a complete study showing a very clear link” between climate change and hurricane strength. “The biggest danger is not making the connection to climate change.”

Like Hurricane Helen, Hurricane Milton is also moving through record-breaking heat. Sea surface temperatures in the Gulf of Mexico are much warmer than usual, even for this time of year. Warmer water acts as fuel for such storms, helping them intensify faster.

Both hurricanes undergo a process known as rapid intensification, where the hurricane’s sustained wind speeds increase by at least 35 miles per hour over a 24-hour period. This trend is becoming more common due to climate change.

The report says the sea surface temperatures that pushed Helen and Milton up were 200 to 500 times warmer due to climate change.

On Monday, Milton experienced a dramatic pressure drop in the center of the hurricane, strengthening to one of the fifth strongest hurricanes ever recorded.

“This storm is definitely explosive,” said Bernadette Woods Plucky, chief meteorologist at the nonprofit research group Climate Central and co-author of the new report.

Using a combination of statistical analysis and detailed climate modeling, the researchers found that climate change and the fossil fuel pollution it causes are about 2.5 times more likely to produce a hurricane as strong as Helen.

This is the third and most extensive preliminary report linking climate change to the heavy rains that killed more than 200 people after Hurricane Helen made landfall in Florida’s Big Bend region on September 26.

Scientists at World Weather Attribution examined rainfall over two days along the coast of Florida, where Helen first hit, and three days of rainfall in mountainous areas in six neighboring states, including North Carolina and Tennessee. Assessed quantity.

They found that coastal rainfall totals are 40% more likely to be this high due to climate change, and inland rainfall totals are 70% more likely to be this high due to climate change. I discovered that there is a sex.

Helen flooded parts of southern Appalachia with more than 6 feet of rain. Floodwaters washed away houses, washed out highways, and cut off access to the town. Much of the recovery work is just beginning.

Damaged buildings in downtown Chimney Rock, North Carolina, after Hurricane Helen passed through on October 2nd.
Alison Joyce/AFP via Getty Images

The World Weather Attribution group is a loose confederation of scientists who rapidly publish extreme findings about whether and how climate change has affected particular events. Twenty-one researchers participated in the new analysis. Although the group uses peer-review methods, its findings are published prior to traditional peer-review when events are new and particularly newsworthy. Previous studies on global weather attribution have withstood further scrutiny by outside scientists and been published in major scientific journals.

Otto said the new results are consistent with two previous analyzes of the effects of climate change on Hurricane Helen, but different researchers defined the parameters of the study in different ways, and there are different He said each report produced different numbers because they focused on geography.

Scientists at World Weather Attribution will run the numbers again for Milton and write a new report.

Source: www.nbcnews.com

Increased hail size and insurance costs may result from climate change

Posted on September 2, 2024 by Igor Mitreski

summary

So far this year, hail — not hurricanes, floods or tornadoes — has caused the most costly weather damage in the United States.
Research suggests that large hailstorms will become more frequent due to climate change.
Next year, scientists are planning the first field study of hail in the United States since the 1970s, and will track hailstorms in the same way they track tornadoes.

Barb Berlin was standing in the garage of her farmhouse near Inman, Nebraska, when she heard a sudden crackling noise.

“I thought it was a gun,” she said.

Then a streak of white appeared, and she realized the sound wasn't a gunshot, but hail.

Fist-sized hailstones pounded on the tin roof of Berlin's garage, and soon others began punching softball-shaped holes in the hood of her Ford Mustang parked outside.

“It was very loud and scary. I prayed a lot,” Berlin said, adding that she was worried about her livestock. “I've never seen hail like that before.”

Hail is a hidden danger: Despite the extreme weather this spring and summer, hail — not hurricanes, floods or tornadoes — caused the most losses in the U.S., according to Gallagher Re, a global reinsurance firm that tracks such data.

And as the planet warms, research suggests large hailstorms like the one observed in Berlin on Monday will become more frequent. A study published last monthThis suggests that the chances of smaller, less damaging hail will decrease.

A study by researchers at Northern Illinois University projects that the frequency of hailstones larger than about 1.5 inches could increase by 15% to 75%, depending on the amount of greenhouse gas pollution humans emit.

Hail occurs when thunderstorms circulate raindrops in the upper layers of the atmosphere, and typically occurs where temperatures are between -22°F and 14°F. Climate change affects hail because warmer temperatures create more energy to push air upwards. In a thunderstorm.

“We expect to see stronger updrafts in the future as the atmosphere becomes more unstable,” said Victor Gensini, a professor of meteorology at Northern Illinois University and lead author of the study.

According to the study, these strong updrafts allow hail to remain in the right places in the storm longer, allowing more ice to accumulate before the hail becomes too heavy and falls to the ground.

“Imagine trying to balance a ping pong ball on an upside-down hair dryer pointing up into the sky,” Gensini said, explaining how updrafts lift hailstones. “Now try balancing a baseball or a grapefruit. You'll need a stronger updraft to…
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Source: www.nbcnews.com

New study indicates that increased UV exposure may be beneficial for health in sun-deprived nations

Posted on August 20, 2024 by Igor Mitreski

A recent study indicates that individuals in the UK Biobank who utilized solariums and resided in regions with high annual average residential shortwave radiation were at a decreased risk of death from various causes, including cardiovascular disease and cancer. Solarium users also exhibited a lower risk of non-cardiovascular/cancer mortality.

Higher exposure to UV light was associated with lower all-cause mortality, cardiovascular disease mortality, and cancer mortality.

“In the UK and other nations with substantial European descendant populations, the emphasis of public health messaging has been on the dangers of ultraviolet (UV) exposure,” stated Professor Chris Dibben from the University of Edinburgh and his team.

“This is particularly concerning considering the established connection between UV radiation and melanoma development.”

“New findings suggest that the benefits of UV exposure might outweigh the risks, especially in low sunlight settings.”

“Among a group of Swedish women, those with higher sun exposure had a longer life span compared to those who avoided the sun.”

“The reduction in mortality rates is mainly linked to decreased cardiovascular and non-cardiovascular/non-cancer mortality.”

“In a study of Swedish women with moderate sun exposure habits, fair-skinned women had an 8% lower overall mortality rate compared to non-fair-skinned women.”

The study utilized genetic and health data from UK Biobank to examine UV exposure in 395,000 individuals in the UK.

Participants were limited to individuals of European descent with fair skin due to the impact of skin pigment on the body’s response to UV radiation.

Researchers utilized two criteria to identify individuals with higher UV exposure levels.

They assessed participants’ geographical locations to determine their average yearly solar energy exposure and whether they utilized sunbeds.

Living in regions with elevated UV levels, like Cornwall, was correlated with a lower risk of dying from cardiovascular disease and cancer (19% and 12% respectively) compared to regions with lower UV levels, such as Edinburgh and Glasgow.

Use of sunbeds was connected to a 23% reduced risk of cardiovascular disease death and a 14% lower risk of cancer-related death compared to non-users.

Given that sunbed users might also engage in more sunbathing, this result could reflect broader sun-seeking behaviors.

Individuals with higher estimated UV exposure showed a slightly greater risk of melanoma diagnosis but not an increased risk of mortality from melanoma.

“Our study contributes to the mounting evidence indicating that relatively high UV exposure in low-light environments could be advantageous for health,” Prof Dibben remarked.

“While increased UV radiation exposure may elevate skin cancer risk, this risk seems to be outweighed by the considerable reduction in cancer and cardiovascular-related disease mortality.”

“Dermatologists have traditionally only considered sunlight’s potential harm to the skin based on experiences of white individuals in sunny nations like Australia,” noted Professor Richard Weller from the University of Edinburgh.

“It is essential to safeguard your skin during periods of very high UV index, but this study indicates that the balance of benefits and risks from sun exposure in the UK may differ significantly from sunnier locales.”

Reference: Survey results Published in the journal Health and location.

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Andrew C. Stevenson others2024. Higher UV exposure is associated with reduced mortality: analysis of data from the UK Biobank cohort study. Health and location 89: 103328; doi: 10.1016/j.healthplace.2024.103328

Source: www.sci.news

California facing increased heat and fire risks leading up to Fourth of July weekend

Posted on July 2, 2024 by Igor Mitreski

California is bracing for a dangerous combination of extreme heat and high fire risk this week as people across the state celebrate Independence Day outdoors. Temperatures in the Sacramento Valley could soar to 115 degrees Fahrenheit, according to meteorologist Kate Forrest from the National Weather Service in Sacramento. Heat warnings have been issued for the region starting Tuesday and are expected to last through Saturday.

Forecasters anticipate the heat wave to start in inland California on Tuesday before spreading to the Pacific Northwest and Southern California later in the week. Heat watches, warnings, and advisories will be in effect across the West on Tuesday from southern Oregon to southeastern California’s low desert according to the National Weather Service.

The increase in temperatures is due to a strong high-pressure system lingering in the region. Governor Gavin Newsom has instructed emergency officials to activate the state’s operations center in response to the upcoming heatwave.

The hot weather could see nighttime temperatures exceed 80 degrees Fahrenheit in some areas, with inland California facing “extreme” conditions by Friday, as indicated on the Heat Risk Map from the Centers for Disease Control and Prevention and the National Weather Service.

Southern Oregon, including the Medford area, is also under a heat watch through Saturday. Meanwhile, Pacific Gas & Electric has warned of potential power outages in 10 California counties on Tuesday due to high winds and dry conditions.

Given the high temperatures and dry conditions, there is an increased risk of wildfires, prompting caution during Fourth of July celebrations involving fireworks. The California Department of Forestry and Fire Protection is monitoring 13 active fires in the state.

Climate change has been linked to the increased frequency and intensity of heat waves and wildfires. Analysis from Climate Central shows that regions like the Sacramento Valley are experiencing more fire-prone weather compared to previous decades.

With heat waves growing in frequency and duration, it is important for residents to take precautions to stay safe during extreme weather events.

Source: www.nbcnews.com

Increased risk of heart attack and stroke associated with Xylitol sweeteners

Posted on June 6, 2024 by Igor Mitreski

Xylitol is often marketed as a “natural” way to sweeten drinks and foods.

Pixelshot/Alamy

Xylitol, a sweetener commonly found in sugar-free drinks, chewing gum and toothpaste, has been shown to increase the risk of heart attack and stroke.

Often marketed as “low carb,” “natural,” or “keto-friendly,” xylitol is a sugar alcohol found in fruits and vegetables, but at levels roughly 1,000 times lower than what’s added to commercial products. It can also be prepared artificially. Chemical reactions from plant materials.

last year, Stanley Hazen Hazen and his colleagues at the Cleveland Clinic in Ohio found that the sweetener erythritol was associated with an increased risk of cardiovascular disease. Suspecting that xylitol might also affect heart health, Hazen surveyed 3,306 adults in the United States and Europe.

The researchers took a single blood sample from participants to measure their xylitol levels after an overnight fast, and found that over a three-year follow-up, those with the highest blood xylitol levels were one-third more likely to develop cardiovascular disease, such as a heart attack or stroke.

To better understand this trend, the researchers looked at the effects of xylitol in the lab on human blood cells called platelets, and on platelet activity in mice. Platelets crowd together at the site of an injury to prevent bleeding, but they can also clot within blood vessels. This can affect blood supply to the heart and brain, increasing the risk of cardiovascular disease.

The researchers found that human platelets cultured in xylitol showed signs of being more likely to clot than those cultured in saline, and blood clots formed significantly more quickly in the veins of mice injected with xylitol.

Finally, the team tracked platelet activity in 10 subjects after they drank the same amount of water sweetened with xylitol. Within 30 minutes, plasma xylitol levels increased 1000-fold, and all indicators of platelet clotting readiness improved, especially in subjects with the highest levels of xylitol in their blood.

“This study highlights the urgent need to investigate sugar alcohols and artificial sweeteners,” Hazen said. “While there’s no need to throw away your toothpaste just because it contains xylitol, people should be aware that consuming products high in xylitol may increase their risk of developing blood clot-related conditions.”

Combined with previous research on erythritol, the findings “emphasize the need for systematic research into the effects of artificial sweeteners on cardiovascular disease risk,” the researchers say. Silvia Radenkovic At the University Medical Center Utrecht, Netherlands.

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Source: www.newscientist.com

Investors React to Plans for Increased Spending on AI, Leading to $190 Billion Drop in Meta’s Value

Posted on April 25, 2024 by Igor Mitreski

Meta’s stock price tumbled 15% on Wall Street Thursday in response to commitments to ramp up spending on artificial intelligence, resulting in approximately $190 billion being wiped off the market value of the Facebook and Instagram parent company.

During a conference call on Wednesday, Mark Zuckerberg, Meta’s CEO, emphasized the necessity of increasing spending on AI technology in order to generate “significant revenue” from the company’s new AI products. “There is a need for an increase,” he stated.

The stock price of Meta had previously benefited from stringent cost-cutting measures in 2023, which Zuckerberg referred to as “the year of efficiency.” However, investors were spooked when Meta raised the upper limit of its capital spending guidance from $37 billion to $40 billion on Wednesday.

Meta recently launched Llama 3, the latest iteration of its AI model and image generator, which can update images in real-time while users input prompts. This update also sees the expansion of Meta AI, the company’s AI-powered assistant, to more than 10 markets outside the US, including Australia, Canada, Singapore, Nigeria, and Pakistan. Chris Cox, Meta’s chief product officer, mentioned that the company is still working on implementing this in Europe.

The decline in stock price comes after Meta Inc. experienced a record increase in market value in February, adding $196 billion to its market capitalization following the announcement of its first dividend, which was, at the time, the largest single-day gain in Wall Street history. However, Nvidia, a prominent supplier of chips for AI models, later surpassed this record with a $277 billion profit.

Source: www.theguardian.com

Obesity directly correlated with increased risk of breast cancer, say researchers

Posted on April 18, 2024 by Igor Mitreski

Reading time: 7 minutes

Breast cancer affects thousands of people each year. Scientists have shown that many factors can influence breast cancer, including age, physical inactivity, and obesity. However, it is unclear exactly how obesity and breast cancer are related.

Previous researchers have shown that tissue inflammation in obese patients is related to cancer. Other researchers have shown that obese patients have the following characteristics: specific genetic mutations It is also related to cancer. However, how this mutation acts to generate different types of tumors is not fully understood.

Ha-Linh Nguyen and colleagues recently investigated the relationship between breast cancer and obesity. Nguyen and his team wanted to determine how obesity affects breast cancer by examining the tissue cell and genetic profiles of breast cancer in obese patients. Their goal was to see if doctors could develop more targeted treatments for breast cancer based on the genetic mutations involved.

They collected genetic data from the tumors of more than 2,000 breast cancer patients collected during multiple large-scale breast cancer studies conducted by five accredited cancer research institutions. To ensure that no changes had occurred in the breast tumors, the researchers only used data from patients who had not yet started cancer treatment.

The researchers defined obesity based on the patient’s weight-to-height ratio. body mass index, or BMI. They used patients’ BMI data to classify patients into three categories: obese, overweight, and underweight. An obese patient, her BMI was over 30 kilograms per square meter (kg/m2).²), the BMI of overweight patients was 25–30 kg/m2.²lean patients had a BMI of 18.5 to 25 kg/m.². For reference, the average BMI for adults is approximately 26 kg/m3.².

Patients were then further categorized based on breast tumor type. These categories include patients with tumors that originate in the milk-producing glands of the breast. Invasive lobular carcinoma tumoror a comparison of patients with ILC tumors and patients without specific tumor types.

The researchers also took into account other biological factors used to identify the type of breast cancer. estrogen receptor. Tumors in patients with estrogen receptor-positive breast cancer contain receptors that use the hormone estrogen to stimulate tumor cell growth. The tumors of breast cancer patients who are estrogen receptor-negative do not contain this receptor.

They also looked at another way to determine the type of tumor, a method called. HER2 factor. HER2-positive breast cancer patients contain a protein called human epidermal growth factor 2, which allows cancer cells to multiply rapidly. The researchers used these biochemical markers to classify patients by tumor type, and then used statistical analysis to distinguish between tumor types in obese patients and those in lean and overweight groups. We compared the types.

Researchers found that in obese patients with non-specific tumors that are estrogen receptor positive and HER2 negative, BMI influences breast cancer in the same way that age influences cancer development. The researchers explained that as we age, the body’s immune response slows down, giving cancer cells more time to accumulate before the body reacts and stops the process. They suggested that these results support the idea that both age and obesity are risk factors for developing breast cancer.

The scientists then looked at whether the tumors in each group had one or more cancer-causing mutations. The research team specifically looked at genes that researchers had previously shown had mutations that cause breast cancer. They also examined tumor DNA to see if there were mutations that caused deletions or amplifications of specific parts of the DNA. Change number of copies.

Researchers found different genetic mutations in patients with different BMIs. They found that a gene involved in cell division signaling, called P1K3CA, was less mutated in obese patients who were estrogen receptor positive, HER2 negative, and had unspecific tumors. Mutations in two other HER genes, CCND1 and CCNE1, were more common in obese patients with estrogen receptor-positive tumors.

The researchers concluded that their study showed a genetic link between breast cancer and obesity. They suggested that some genetic mutations found in tumors of obese patients, particularly CCND1 and CCNE1 mutations, may enable targeted breast cancer treatments. They suggested that future researchers should investigate how the biochemical pathways these genes are associated with actually contribute to breast cancer formation to better develop treatments. .

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original research: Obesity-related changes in the molecular biology of primary breast cancer

research has been published:July 21, 2023

research author: Harinh Nguyen, Tatiana Geukens, Marion Mehtens, Samuel Aparicio, Ayse Bassez, Ake Borg, Jane Block, Anejan Brooks, Carlos Caldas, Fatima Cardoso, Maxim de Schepper, Mauro DeLorenzi. , Caroline A. Drucker, Anuska M. Glass, Andrew R. Green, Edoardo Isnardi, Jörn Eifjords, Hazem Kout, Stian Knapskog, Savitri Krishnamurthy, Sunil R. Lakhani, Anita Langerod, John W. M. Martens, Amy E. McCart-Reid, Lee Murphy, Stefan Nauraz, Selina Nick-Zinal, Ines Nebelsteen, Patrick Neven, Martine Picard, Coralie Ponsetto, Kevin Puni, Colin Purdy, Emad A. Raka, Andrea Richardson, Emile Rutgers, Anne Vincent-Salomon, Peter T. Simpson, Marjanka K. Schmidt, Christos Sotiriou, Paul N. Spann, Kiat. Tee Benita Tan, Alastair Thompson, Stefania Tommasi, Karen van Baeren, Marc van de Wivel, Steven van Leer, Laura van't Veer, Giuseppe Viale, Alan Viali, Hanne Voss, Anke T. Witteveen, Hans Wildyas, Giuseppe Floris, Abhishek D. Garg, Anne Smeets, Dieter Lambrecht, Elia Biganzoli, Francois Richard, Christine Desmet

The research was conducted at the following locations:: Katholieke Universiteit Leuven (Belgium), Lund University (Sweden), Netherlands Cancer Institute (Netherlands), University of Cambridge (UK), Champalimaud Clinical Center/Champalimaud Foundation (Portugal), University of Lausanne (Switzerland), SIB Swiss Institute of Bioinformatics (Switzerland), Antoni van Leeuwenhoek Hospital (Netherlands), University of Nottingham (UK), University of Iceland (Iceland), University Hospitals of Leicester NHS Trust (UK), University of Bergen (Norway), and University of Texas MD Anderson. University of Queensland, Herston (Australia), Royal Brisbane and Women's Hospital, Herston (Australia), Oslo University Hospital, Ullenjausen (Norway), Erasmus University Medical Center, Rotterdam (Netherlands), University of Manitoba , Manitoba Institute for Cancer Treatment (Canada), University Hospital Leuven (Belgium), Jules Bordet Institute and Free University of Bruxelles (Belgium), European Organization for Research and Treatment of Cancer (EORTC) Headquarters (Belgium), University of Dundee (UK) , Nottingham University Hospitals NHS Trust (UK), Johns Hopkins University (USA), Netherlands Cancer Institute (Netherlands), Institut Curie, PSL Research University (France), Radboud University Medical Center (Netherlands), Sengkang General Hospital ( Singapore), National Cancer Center (Singapore), Baylor College of Medicine (USA), IRCCS Istituto Tumouri “Giovanni Paolo II” (Italy), University of Amsterdam (Netherlands), University of Antwerp (Belgium), UCSF Helen Diller Family Institute Cancer Center (USA), European Institute of Oncology IRCCS (Italy), University of Milan (Italy), Synergie Lyon Cancer, Plateforme de Bio-informatique 'Gilles Thomas' (France), Università degli Studi di Milano (Italy)

This research was funded by: Luxembourg Cancer Foundation, European Research Council, University of Leuven.

Availability of raw data: Data from the ICGC cohort includes: ICGC Data Portalthe data from ELBC includes: gene expression omnibus Accession number GSE88770 provides access to data from MINDACT. EORTCindividual patient read count data can be accessed below. bio keythe raw sequence reads include European Genomic Phenomena Archive Research No. EGAS00001004809 and data accession number. EGAD00001006608

Featured image credit: Photo provided National Cancer Institute upon unsplash

This summary was edited by: Aubrey Zirkle

Source: sciworthy.com

Why has anxiety increased over the past decade?

Posted on April 3, 2024 by Igor Mitreski

In recent years, I’ve noticed more and more people sharing their experiences with anxiety, whether it’s celebrities opening up in interviews or friends chatting over drinks. This got me thinking. Are more people experiencing anxiety these days, or are they just more willing to talk about it?

This apparent increase seems to be seen in studies on the prevalence of anxiety, but when you dig into the details, the picture is not so clear. As for what’s behind this potential increase, the COVID-19 pandemic is the obvious culprit, but it’s not the only one; economic and political factors may also be at play.

First, let’s look at the pandemic. “This was a phenomenon that none of us had ever experienced before, and it was a global problem that understandably caused a lot of stress,” he says. David Smithson at the charity Anxiety UK. “Who isn’t worried?”

growing anxiety

As the pandemic began, anxiety levels increased and the World Health Organization reported: Anxiety disorders increased by 25.6% In 2020, lockdowns and other restrictions were introduced and people faced an unknown virus and its impact on their lives. However, this increase was not sustained, according to a review of 177 studies targeting people in high-income countries. Levels decline as pandemic continues.

This is consistent with Smithson’s experience. “We have seen an increase in demand for our support services for about two years since the start of the pandemic,” he says. “Over the past 12 months or so, we have seen a drop in demand…

Source: www.newscientist.com

Is the potential for more powerful electric bikes cause for concern over increased fire risk?

Posted on March 23, 2024 by Igor Mitreski

The UK Government has initiated a consultation to gather public and industry input on increasing the legal power of electric bike models from 250W to 500W in the UK. This move has sparked concerns in the fire protection community.

Electric bicycles utilize various types of batteries, with lithium-ion technology being the common choice. These batteries come in different shapes and sizes, such as cylindrical or box-shaped configurations.

Battery packs in electric bikes are composed of multiple cells connected in series and parallel to provide the necessary voltage and capacity. Incidents of fires linked to lithium-ion batteries are on the rise, posing risks to users of electric bikes and e-scooters.

Recent data disclosed in May 2023 by the Guardian newspaper revealed that defective electric bikes and e-scooters have caused injuries to 190 individuals and claimed eight lives in the UK. The London Fire Brigade noted a substantial increase in battery-related fires in 2023, with a rise of 78% compared to the previous year.

Potential causes of fires in lithium-ion batteries include mechanical or thermal shock, overcharging, and reactive materials interacting with each other, leading to heat generation and abnormal electrical behavior. Despite the benefits of higher wattage batteries in electric bikes, there are concerns about the increased risk of fires and other safety issues.

To mitigate the risk of battery fires, users are advised to avoid tampering with batteries, charge them within the recommended parameters, and store them in a safe environment away from flammable materials. Adherence to manufacturer guidelines and proper disposal of damaged batteries are crucial in preventing incidents of fires.

Source: www.sciencefocus.com

Coastal Cities in the US Facing Increased Flooding Risk Due to Rising Sea Levels by 2050

Posted on March 6, 2024 by Igor Mitreski

New Orleans is at risk of more flooding than expected due to land subsidence

William A. Morgan/Shutterstock

Sea levels are rising faster than expected in U.S. coastal cities, primarily due to land subsidence from groundwater and fossil fuel extraction. This means up to 518,000 additional people living in these areas could be at risk of major flooding by 2050 if adequate protection is not in place.

Coastal cities often experience subsidence, where the land gradually sinks over time. One of the biggest factors causing this is the compaction of the earth by extracting resources such as water and fossil fuels from the ground.

To investigate how land subsidence and sea level rise will impact coastal communities. leonard owenhen The Virginia Tech researchers created a model based on land elevation changes in 32 major coastal cities, including Boston and San Francisco, and sea level rise projections through 2050.

Researchers found that cities on the Atlantic and Gulf coasts, such as New Orleans, have lower elevations and are sinking faster. It is sinking at least two millimeters more per year than other cities in the region, increasing the risk of future flooding. . Urban areas along the Pacific coast are better protected from rising sea levels because of their higher elevations.

“We were surprised to see that Biloxi, Mississippi, experienced the most rapid subsidence,” Owenhen says.

They also found that existing flood risk assessments in the United States do not take into account the combined effects of land subsidence, underestimating its threat. Researchers have found that nearly 1,400 square kilometers more land will be at risk of flooding by 2050 than current estimates. That means, in total, 1 in 50 people and 1 in 35 homes in 32 cities are at risk. .

This would put an additional 518,000 people and more than 288,000 homes at risk of flooding.

The study looked at flood risk for dozens of coastal U.S. cities by 2050.

Image courtesy of Leonard Owenhen

These findings highlight the urgent need to strengthen U.S. flood protection now, team members say Manuchel Shirzai, also at Virginia Tech. “Individual cities will need to adapt differently. New Orleans will need to strengthen city-wide flood protection, while San Francisco will probably only need to protect its critical infrastructure.”

Other things could be done to reduce the threat. “If land subsidence is being caused by groundwater extraction, oil and gas development, or other human-induced stresses, we need to do everything we can to reverse these trends before it’s too late.” he says. Simon Anisfeld At Yale University.

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Source: www.newscientist.com

Exposure: A decade ago, the auto industry was alerted to the increased theft risk of keyless car technology.

Posted on February 25, 2024 by Igor Mitreski

The automobile industry disregarded warnings from over a decade ago about the risks of keyless technology in modern vehicles leading to a rise in vehicle thefts, as revealed by an investigation in the automotive sector. The observer can disclose.

Legal and computer experts had cautioned that keyless entry and vehicle software were vulnerable to being “hacked” due to inadequate security measures.

Findings indicated that car owners could potentially face theft without any evidence of forced entry in the future.

The surge in vehicle crimes through keyless entry has resulted in record hikes in car insurance costs, with some drivers now confronted with premiums exceeding £2,000 annually. Car thefts in England and Wales reached a decade-high in the year leading up to March 2023.

Observers discovered the following:

Devices camouflaged as gaming consoles, referred to as ’emulators’, are utilized by thieves to mimic electronic keys and steal vehicles within 20 seconds. This is applicable to Hyundai and Kia models.

The ‘smart’ devices are available for purchase online for up to £5,000, allowing criminals to breach a vehicle’s computer system and program a new key.

Police in various regions report a high rate of keyless car thefts and are resolving some cases within 24 hours, even with CCTV footage available.

Nick Freeman, an attorney specializing in the automotive industry, remarked: “The automotive sector was neglectful as they were forewarned about this new technology emerging. It’s a dire situation where individuals are compelled to pay exorbitant insurance premiums.

In November, Jaguar Land Rover announced a £10m investment to enhance the security of high-target car models manufactured between 2018 and 2022. The observer Investigations highlighted similar security vulnerabilities in other vehicles, prompting Hyundai to acknowledge this weekend that criminals had “utilized a device to unlawfully disable smart key lock systems” to access their vehicles. They affirmed the immediate implementation of preventive measures.

A report from 2011 by researchers at the University of California and the University of Washington indicated the potential for attacks on the software in contemporary cars, potentially allowing breaching the car’s telematics system to unlock doors and start the engine without authorization.

An article published in the April 2012 Computer Law and Security Review by specialist barrister Stephen Mason highlighted the vulnerability of keyless systems, warning that vehicles could be stolen without any forced entry unless security enhancements were introduced.

Mr. Mason expressed, “There was a sense of complacency and lack of concern in the automotive sector that hesitated to invest in proper security. We now have state-of-the-art cars with advanced technology, yet owners rely on traditional steering locks for theft protection.”

The Society of Motor Manufacturers and Traders (SMMT) refutes claims of security lapses in the industry, suggesting it is engaged in an ongoing battle with criminals. SMMT CEO Mike Hawes stated: “Automakers continuously introduce new technology to outsmart criminals. This investment has significantly reduced vehicle theft over the past three decades.

“Manufacturers are continually strengthening their security systems, but technology alone cannot prevent all thefts, which is why our industry collaborates closely with law enforcement, insurers, and other security stakeholders.”

The Home Office reports an overall reduction in vehicle crime, including thefts from vehicles. A spokesperson emphasized the importance of law enforcement in addressing motor vehicle crime and commended their commitment to pursuing thorough investigations.

“We have made significant strides in combating vehicle crime, which has decreased by 39% since 2010. New regulations in the Criminal Justice Bill will outlaw electronic devices used in vehicle theft.”

Source: www.theguardian.com

Increased Cancer Risk in Relatives of Men with Infertility

Posted on February 22, 2024 by Igor Mitreski

The study looked at men who produced less than 1.5 million sperm per milliliter of semen, which is considered to produce very few or no sperm.

Joshua Resnick/Shutterstock

Relatives of men who have infertility problems may be at increased risk of cancer, and the odds vary widely from family to family.

Research suggests that certain relatives within three generations of such men are more likely to develop a variety of cancers, including cancers that affect the colon, testicles, and uterus. However, the risk varies by family lineage and whether the man is infertile or subfertile.

Male infertility has been linked to multiple health problems; cardiovascular diseases etc.. Previous research has also pointed out the following: Association between male infertility and increased cancer risk in relatives of such men.

Joey Ramsay Researchers at the University of Utah in Salt Lake City suspected this might vary from family to family. To find out, they analyzed the sperm counts of 360 men who produced fewer than 1.5 million sperm per milliliter of semen and 426 men who produced no sperm at all. These men were matched in age to more than 5,600 of his others with whom he had at least one biological child. Researchers do not know whether any of the participants were transgender.

Next, they obtained information on cancer diagnoses in the men's first-, second-, and third-degree relatives from Utah's database.

The research team found that relatives of men with low sperm counts within three generations were more likely to develop colon and testicular cancer compared to the general population, and some of those related to men with low sperm counts They discovered there was a high chance of developing sarcoma, Hodgkin said. Lymphoma, cancer of the uterus and thyroid. Both of these groups had much higher rates of bone and joint cancer than the general population.

The researchers then used specially developed software to determine the increased risk of cancer combinations in 34 body regions within different families (both fertile and infertile groups). We have detected a tendency to This resulted in “clustering” that allowed trends within families to be detected.

Two-thirds of male relatives who did not have sperm were at no higher risk of cancer than the general population. However, other families showed a significantly increased risk of various types of cancer, and that risk varied by family lineage, with higher risks for childhood, adolescent, and young adult cancers. There were people too.

Relatives of men with low sperm counts all had an increased risk of at least one type of cancer compared to the general population, but the degree of risk and type of condition varied.

It is unclear why this increased risk occurs, but it may be due to genetic factors or common environmental exposures among relatives. It is hoped that further research will investigate this and lead to tests that identify families at higher risk, Ramsay said.

topic:

Source: www.newscientist.com

SEC Approval of Spot Bitcoin ETF Leads to Increased Volatility in the Market – Blockchain News, Opinion, TV, Jobs

Posted on January 16, 2024 by Igor Mitreski

Bitcoin (BTC) closed last week at around $41,750, down 5.0% from the first week of the new year, to close at around $43,750. The price showed significant fluctuations, mainly influenced by the increased market dynamics due to the approval of the BTC Spot ETF. The week began with a strong uptrend in anticipation of approval on Monday, with prices rising 9.0% to nearly $47,000. BTC approached $48,000 on Tuesday, but the false news about confirmation encountered significant volatility, causing a drop below $45,000 before stabilizing near $46,000 overnight.

On Wednesday, the SEC granted approval for the BTC Spot ETF, leading to heightened volatility, especially on Thursday when ETF trading began. After soaring to around $49,000, BTC began a significant downtrend, especially on Friday, when the price fell by 7.7% to below $43,000. Prices gradually declined over the weekend, ultimately ending the week at around $41,750.

The launch of the BTC Spot ETF has increased market activity. An analysis of daily trading volume on centralized exchanges for the seven-day period from January 8th to 14th showed that daily trading volume reached nearly $50 billion, the highest since November 2022. The launch of ETFs has increased activity in the entire market, and not just in BTC.

From January 8th to 14th, BTC's daily trading volume was recorded at $17.8 billion, an increase of 26% from the $14.1 billion recorded the previous week. Ethereum (ETH) recorded a total daily trading volume of $7.7 billion during the same period, an 83% increase from the $4.2 billion recorded the previous week, indicating increased activity across the market.

The recent strength of the market compared to BTC is further substantiated by analyzing BTC's dominance in terms of market capitalization relative to the overall digital asset market. At the end of the week, BTC's share was 51.1%, down 5.4% from 54.0% the previous week.

BTC price trends, coupled with volume data and the performance of specific altcoins, indicate that it adheres to the typical “buy the rumor, sell the news” pattern associated with major market events. Market participants predicted the ETF's approval 90% of the time and adjusted their portfolios accordingly prior to SEC approval.

During Q4 2023, BTC showed significant strength, with the price increasing by 57% to around $42,300 from $27,000 at the end of Q3. As BTC reached almost $49,000 after approval, investors took profits on positions initiated at lower BTC price levels and transferred their capital to altcoins, as evidenced by its decline in dominance over the past week. began to be redistributed.

This pattern is common and does not indicate a failed ETF launch. In the first two days of trading, the 11BTC Spot ETF closed with approximately $1.4 billion in cumulative inflows, partially offset by $600 million in outflows from the Grayscale Bitcoin ETF (GBTC). Net inflows were approximately $800 million.

The GBTC outflow was facilitated by the fact that it was not a new product launch, but rather a conversion from an existing Bitcoin trust holding over 600,000 BTC. Grayscale has higher management fees (1.5%) compared to most of its competitors (0.2%/0.3%), leading some investors to withdraw from Grayscale and opt for more favorable management fees. May reinvest in other BTC ETFs with fees.

Source: the-blockchain.com

Holiday Season Brings Increased Risk of Penile Fractures, Doctors Warn

Posted on December 21, 2023 by Igor Mitreski

Christmas is a joyful time for many, but doctors have cautioned that there is a significant rise in embarrassing bedroom injuries during this festive season.

Warning: This story contains references to sexual assault.

Urologists at the Ludwig-Maximilians University in Munich, Germany, have stated that a penile fracture is considered a medical emergency and is typically accompanied by an audible cracking sound and intense pain.

They caution that such injuries are the result of “strong flexing of the erect penis during aggressive sexual intercourse characterized by unusual sexual positions (e.g. ‘reverse cowgirl’)”.

In addition to the “audible cracking” and “severe pain,” doctors added that there is also rapid loss of erection, swelling, and bruising afterwards.

A study using German hospital data on 3,421 men who sustained penile fractures between 2005 and 2021 found that penile fractures increased during the festive period. The study, published in the British Journal of Urology International, also found that penile fractures increased on weekends and during the summer, but not on New Year’s Eve.

The researchers added that hospitalizations due to injuries were not affected by the COVID-19 pandemic or lockdown. The average age of penile fracture in men was 42 years.

Read more from Sky News:
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“Our findings ring an alarm (not jingle bells).”

The study also found that penile fractures are “most likely to occur during sex in unconventional scenarios,” such as extramarital sex or in “unusual locations.”

“Our analysis shows that penile fractures occur during times when couples are enjoying relaxing time, such as Christmas, weekends, and summer,” the authors write.

“Of course, we cannot recommend not having sex during such a period, but our findings ring alarm bells (rather than jingle bells).”

The authors, who clearly enjoy writing about their findings with festive puns, concluded: “Thus, in this case, playing ‘Home Alone’ during Christmas and the holidays seems like a good idea.” ing.

Source: news.sky.com

New EU initiative to provide increased support for AI startups using supercomputers for model training

Posted on December 20, 2023 by Igor Mitreski

The European Union plans to support its own AI startups by providing access to processing power for model training on the region’s supercomputers, announced and launched in September. According to the latest information from the EU, France’s Mistral AI is participating in an early pilot phase. But one early learning is that the program needs to include dedicated support to train AI startups on how to make the most of the ‘s high-performance computing. “One of the things we’ve seen is that we don’t just provide access; facility — In particular, the skills, knowledge and experience we have at our hosting centers — to not only facilitate this access, but also to develop training algorithms that take full advantage of the architecture and computing power currently available at each supercomputing center. however, an EU official said at a press conference today. The plan is to establish a “center of excellence” to support the development of specialized AI algorithms that can run on EU supercomputers. Rather than relying on the processing power provided by supercomputers as a training resource, AI startups may be accustomed to training their models using specialized computing hardware provided by US hyperscalers. Access to high-performance computing for AI training programs is therefore being enhanced with support wrappers, said EU officials speaking in the background ahead of the formal ribbon-cutting, mare nostrum 5a pre-exascale supercomputer, which goes live on Thursday at the Barcelona Supercomputing Center in Spain. “We are developing a facility to help small and medium-sized enterprises understand how best to use supercomputers, how to access supercomputers, how to parallelize algorithms so that they can develop models in the case of AI,” said a European Commission official. “In 2024, we expect to see a lot more of this kind of approach than we do today.” “AI is now considered a strategic priority for the , they added. “Next to the AI Act, as AI becomes a strategic priority, we are providing innovation capabilities or enabling small businesses and startups to make the most of our machines and this public infrastructure. “We want to provide a major window of innovation.” ” Another EU official confirmed that an “AI support center” was in the works, including a “special . “What we need to realize is that the AI community hasn’t used supercomputers in the past decade,” they noted. “They’re not new users of GPUs, but they’re new to how to interact with supercomputers, so we need to help them. “A lot of times the AI community comes from a huge amount of knowledge about how many GPUs you can put in a box. And they’ve been very good at it. What you have is a bunch of boxes with GPUs, and you need additional skillsets and extra help to scale out the supercomputer and exploit its full potential.” The bloc has significantly increased its investment in supercomputers over the past five years, expanding its hardware to regionally located clusters of eight machines, interconnected via a Terabit network. We also plan to create federated supercomputing resources. Accessed in the cloud, it is available to users across Europe. The EU‘s first exascale supercomputers are also expected to come online in the next few years, with one in Germany (likely next year) and a second in France (expected in 2025). The European Commission also plans to invest in quantum computing, providing hybrid resources co-located with supercomputers and combining both types of hardware, so that quantum computers can act as “accelerators”. There are plans to acquire a quantum simulator that will As the committee states, it is a classic supercomputer. Applications being developed on the EU‘s high-performance computing hardware include projects that simulate Earth’s ecosystems to better model climate change and weather systems. destination earth and one more thing needs to be devised Digital twin of the human body This is expected to contribute to the advancement of medicine by supporting drug development and making personalized medicine possible. Leveraging his resources in supercomputing to launch his AI startup has recently been announced, especially after the EU president announced this fall that his AI model would have computing access to his training program. It is emerging as a strategic priority. The bloc also announced what it called the “Large-Scale AI Grand Challenge.” This is a competition for European AI startups “with experience in large-scale AI models” and aims to select up to four promising domestic startups for a total of four. Access to millions of hours of supercomputing to support foundational model development. According to the European Commission, there will be a prize of 1 million euros to be distributed to the winners, who will be able to release their developed model or publish their research results under a non-commercial open source license. It is expected. The EU already had a program that provided industry users with access to core hours of supercomputing resources through a project recruitment process. However, the bloc is increasing its focus on commercial AI with dedicated programs and resources, and there is an opportunity to incorporate the growing supercomputing network into a strategic power source for expanding ‘Made in Europe’ general purpose AI. They are intently aiming for this. Thus, France’s Mistral, an AI startup that aims to compete with US infrastructure model giants like OpenAI and claims to offer “open assets” (if not fully open source), is an early adopter of It seems no coincidence that the beneficiaries of the Commission‘s Supercomputer Access Program. (That said, the technology company, which just raised €385 million in Series A funding that includes US investors including Andreessen Horowitz, General Catalyst and Salesforce, is at the front of the line for computing giveaways.) That may raise some eyebrows, but hey, it’s another sign of the high-level strategic bets being made on “big AI.”) The ‘s “Supercomputing for AI” program is still in its infancy, so it’s still unclear whether there will be enough benefits in model training to warrant reporting from dedicated access. (We reached out to Mistral for comment, but he did not respond as of press time.) But the committee’s at least hope is that by focusing support on AI startups, they will be able to move into high-performance computing. It is about being able to leverage investments. The construction of supercomputer hardware is increasingly being procured and configured with AI model training in mind, and this is due to the fact that local, hyperscalar-like US AI giants are starting at a disadvantage. This will be a competitive advantage for the AI ecosystem. “We don’t have the massive hyperscalers that the Americans have when it comes to training this kind of basic model, so we’re using supercomputers and a new generation that is increasingly compliant with AI. “We intend to develop a supercomputer,” a committee official said. “The objective in 2024, not just with the supercomputers that we have now, is to move in this direction so that even more small and medium-sized businesses can use supercomputers to develop these basic models. It is to do.” The plan includes acquiring “more dedicated AI supercomputing machines based on accelerators rather than standard CPUs,” they added. Will the ‘s AI support strategy align with or diverge from certain member states’ ambitions to develop national AI champions? We heard a lot about this during the recent difficult negotiations to develop the ‘s AI rulebook, in which France took the lead in pushing forward the AI rulebook. Regulatory carve-outs to the underlying model It drew criticism from small and medium-sized businesses. – As seen. But Mistral’s early presence in the ‘s supercomputing access program may suggest a consensus.

Source: techcrunch.com

Bitcoin consolidates with increased profitability for long-term holders: Blockchain news, opinions, TV, and job opportunities

Posted on November 21, 2023 by Igor Mitreski

Last week, Bitcoin (BTC) ended at around $37,350, an increase of 0.8% compared to the previous week’s closing price of $37,000. It started with notable volatility, with BTC prices falling to $34,800 on Tuesday, but then made a strong recovery and reached almost $38,000 on Wednesday. BTC then fell again to $36,000 on Thursday. The second half of the week saw an uptick, with BTC ending the week at around $37,350.

BTC dominance, which measures Bitcoin’s market capitalization relative to the overall digital asset market, recovered after two consecutive weeks of decline and settled at around 52.6%. This represents an increase of 0.3% compared to the previous week and indicates a slowing in the dispersion of liquidity across the market following two weeks of solid momentum in the altcoin sector.

The recent rise in altcoin performance is supported by an analysis of the Total3 metric, which considers the sum of the market capitalizations of the top 125 altcoins. The index now stands at around $416.1 billion, the highest level since August 2022. This follows a solid rally led by the Bitcoin and ETF Spot stories in recent months, highlighting substantial positive momentum across the market, with significant gains in early May 2022 approaching market cap. It reached a level not seen since the collapse of UST-Luna, which triggered a recession.

Confirming the uptrend, several BTC indicators are showing strong momentum. Approximately 80% of addresses holding Bitcoin are currently profitable, indicating solid accumulation during the 2022 recession. Only about 20% of addresses have an average purchase price above $37,000, confirming that a bottom is likely to form sometime in 2022. This accumulation by short-term holders by long-term holders is typically seen in the later stages of a bear market. A cycle bottom is established. This is further supported by the unchanged BTC supply over the past 12 months, currently accounting for 70.2%, indicating the long-term commitment of most investors. Furthermore, the Bitcoin Irritant Supply Index, which measures the supply held in wallets with minimal spending history, reached an all-time high of 15.4 million BTC. This is consistent with our previous hypothesis depicting a recent surge in long-term holders who continued to accumulate assets without selling them during the 2022/2023 economic downturn, and was associated with the sale of BTC in their wallets. indicates minimal activity.

Examining BTC’s on-chain activity reveals positive trends. His daily transaction count, calculated on a 7-day average, is approaching around 575,000, and his total BTC on-chain transaction volume has reached a level not seen since the end of June. Transaction fees remain relatively high at $4-$5, indicating an overall upward trend in on-chain activity beyond centralized exchanges and financial instruments. This suggests that structural activity and interest are growing harmoniously across different investor cohorts.

Focusing on mining, recent reports indicate that Tether, the issuer of USDT, is expanding into mining with the aim of capturing around 1% of the total hashrate and securing a position in the top 20 mining farms. The company plans to invest $500 million. According to a BitVeria report, during the third quarter, miners focusing on power strategies managed to reduce the average direct BTC production cost by 35% from $21,100 to $13,800. This data highlights a significant improvement in the mining sector’s profitability compared to the challenges experienced through 2022 and parts of 2023.

Source: the-blockchain.com

Researchers discover the science behind our increased appetite for certain foods

Posted on October 25, 2023 by Igor Mitreski

Researchers have made an interesting discovery about the impact of advanced glycation end products (AGEs) found in prepared foods on hunger and health. AGEs, which are produced during cooking processes like baking and frying, enhance the appeal of food but also have negative effects on our well-being. Studies using nematodes have shown that AGEs lead to increased consumption and reduced lifespan, emphasizing the importance of choosing healthier food options.

Scientists at Buck have identified a mechanism that may explain why consuming delicious yet unhealthy food increases our desire to eat more. Overeating and weight gain can result from various factors, including the ready availability of flavorful, high-calorie foods. The researchers at Buck have found that AGEs, a type of chemical found in processed and prepared foods, contribute to increased hunger and a decreased ability to make healthy food choices. This research sheds light on the reasons behind our testing abilities for these foods.

According to Pankaj Kapahi, the lead author of the research study, “This research involving tiny worms has significant implications for human dietary choices and our tendency to overeat certain foods.” He added, “Modern processed foods rich in AGEs are tempting to eat, but we know very little about their long-term effects on our health.” The study was recently published in the journal eLife.

An evolutionary perspective suggests that humans have evolved mechanisms that encourage us to consume as much food as possible when it is readily available. This is because excess calories are stored as fat, which can be utilized during periods of fasting. The preference for flavorful foods, particularly those high in sugar, has been favored by natural selection. However, the mechanisms that make it difficult to resist such foods have remained unclear. AGEs are metabolic byproducts that occur naturally during sugar metabolism in cells but are also formed during cooking processes and are found in many processed foods. AGEs provide the appealing brown color that occurs during cooking, making food more appetizing and harder to resist.

While the Maillard reaction, which occurs when sugars and proteins interact with heat, is well-known for making food taste good, it can have detrimental effects on the body. The resulting AGEs cause inflammation and oxidative damage, which contribute to various health issues such as blood vessel stiffness, high blood pressure, kidney disease, cancer, and neurological problems. Accumulation of these metabolic byproducts in different organs is likely one of the main factors in the aging process of organs and organisms overall. It is due to these harmful effects that researchers are studying the impact of AGEs on health.

Even tiny worms used in the Kapahi lab were not immune to the allure and harm of AGEs. Researchers observed that these chemicals not only caused diseases and reduced lifespan but also increased the worms’ appetite for the same substances. The researchers aimed to understand the underlying mechanism by which AGEs promote excessive eating. Through their study, they identified a signaling pathway mediated by specific AGE molecules that promotes feeding and neurodegeneration. They also found that worms lacking the ability to process even naturally occurring AGEs had significantly shorter lifespans. The study is now expanding to mice, where researchers will investigate the relationship between AGEs and fat metabolism.

Understanding this signaling pathway may provide insights into overeating caused by modern diets rich in AGEs. This research highlights the role of AGE accumulation in diseases such as obesity and neurodegeneration and its association with the global rise in age-related diseases.

The key takeaway from their work is a profound realization that our food intake is often controlled by the food itself. To address this, the researchers have personally changed their diets, practicing intermittent fasting to allow the body to utilize fat instead of sugar. They also recommend consuming whole grains to maintain stable glucose levels and utilizing moist heat instead of dry cooking methods, such as steaming or frying. Adding acids when cooking, like when grilling, slows down the formation of AGEs.

In conclusion, this study provides valuable insights into the impact of AGEs found in processed and prepared foods on hunger, overeating, and overall health. It highlights the need for individuals to be conscious of their dietary choices and opt for healthier alternatives to reduce the negative effects of AGE accumulation in the body.

Source: scitechdaily.com