Nothing Ear 3 Review: Stylish Earphones Featuring ‘Super Mic’ Party Trick

The latest translucent noise-cancelling earbuds from Nothing feature an innovative twist: the case includes a high-quality built-in microphone that enables you to communicate simply by pressing a button.

This so-called super microphone caters to those who desire a more direct microphone experience for improved clarity during conversations, recordings, and voice notes, even in bustling environments. It’s particularly suited for individuals who speak directly into the bottom of their phones.

However, this enhancement in the case’s functionality has led to a price increase, with Year 3 now retailing at £179 (€179/$179/AU$299), which is £50 more than the prior model’s launch price. While still competitively priced compared to leading competitors, it’s now closer to the Google Pixel Buds Pro 2 and Apple AirPods Pro 3.

Visible magnets and other features through the earbuds’ case add an intriguing touch to the design. Photo: Samuel Gibbs/The Guardian

Ear 3 maintains Nothing’s hallmark translucent aesthetic, introducing various small design details that set them apart from mundane earbuds, while incorporating aluminum in place of some plastic for a more polished appearance.

The earbuds have been redesigned for enhanced comfort during prolonged listening sessions. Their lightweight and secure fit ensures a snug seal in your ear. The stem features squeeze controls for playback, noise cancellation, volume adjustments, and voice assistant activation. Although somewhat limited, the controls are customizable and function effectively.

The earbuds come in a square, flip-top charging case that is compact yet noticeably heavier this year. With a battery life of 6 hours on a single charge, and with noise cancellation active, you can enjoy at least 22 hours of total playback when utilizing the case for recharging. The case itself charges in slightly over an hour via USB-C and around 2 hours using Qi wireless charging.

Activating the earbuds’ Super Microphone involves pressing and holding the “Talk” button on the case, which emits a subtle sound when the microphone is turned on. Photo: Samuel Gibbs/The Guardian

Equipped with a capable built-in microphone, the earbuds effectively filter out ambient noise, although they may occasionally sound somewhat robotic. The Super Mic offers richer, fuller audio, making it ideal for voice memos, transcription, and calls. Nevertheless, the audio quality doesn’t quite reach the standards for a lapel microphone or similar recording devices.

Specifications

  • Water Resistance: IP54 (splash-proof)

  • Connectivity: Bluetooth 5.4 (SBC, AAC, LDAC)

  • Battery Life: 5.5 hours with ANC (22 hours with case)

  • Earphone Dimensions: 30.5×21.5×20.8mm

  • Earphone Weight: 5.2g each

  • Driver Size: 12mm

  • Charging Case Dimensions: 56×55.5×22.3mm

  • Charging Case Weight: 61g

  • Case Charging: USB-C

Sound Quality and Noise Cancelling

Each earbud comes with three sizes of silicone tips for a comfortable fit and a secure seal. Photo: Samuel Gibbs/The Guardian

These earphones utilize high-quality Bluetooth 5.4 alongside standard SBC and AAC audio formats, with support for LDAC for compatible Android devices. They also offer the capability to connect to two devices simultaneously; however, this may slow the Super Mic’s performance.

Previous models from Nothing have consistently provided excellent value, characterized by easy-to-listen sound with ample detail and clear sound separation. The Ear 3 follows this tradition, offering louder sound with a prominent bass response right out of the box. It’s well-balanced and does not overshadow the overall sound range, while the Nothing X companion app allows for extensive customization if desired.

The noise cancellation effectively reduces common ambient sounds and low-frequency commuting noises, handling higher-pitched disturbances like keyboard taps and conversations better than prior Nothing models. However, it doesn’t quite match the level of noise cancellation provided by higher-end alternatives, such as the AirPods Pro 3.

The transparency mode performs admirably, delivering a natural sound; however, neither mode excels at managing wind noise.

Sustainability

One of the microphones inside the case is adjacent to the USB-C charging port, indicated by a green LED light when active. Photo: Samuel Gibbs/The Guardian

The earbuds and charging case are designed to maintain at least 80% battery capacity survival even after 500 complete charge cycles. Although earbuds themselves are not repairable, they can be replaced individually through service if they fall out of warranty.

The casing is made from recycled aluminum and tin, though Nothing does not provide trade-in options. The estimated carbon footprint of the earbuds stands at 2.87kg.

Price

The cost of the Nothing Ear 3 is £179 (179 EUR/$179/AU$299).

For comparison, the Ear priced at £119, the headphone price for 1 is £299, the Google Pixel Buds Pro 2 costs £219, the Samsung Galaxy Buds 3 Pro is £219, and the Apple AirPods Pro 3 retails for £219.

Verdict

Nothing has introduced some features we haven’t previously encountered in earbuds, such as the integration of a microphone and push-to-talk button directly into the charging case. This concept is original and serves as an excellent alternative to traditional interview or video microphones, albeit lacking in certain aspects.

For non-content creators, this setup is perfect for phone calls, recording voice notes, and interacting with your phone’s AI assistant, resembling a modern dictaphone. However, personal frequency of use may vary.

The earbuds present a noteworthy offering from Nothing, delivering impressive sound quality, effective noise cancellation, robust battery life, and a comfortable fit, making them a refreshing alternative to typical earbuds.

While the price increase to £180 places them alongside some top-tier earbuds, they haven’t yet reached that elite status. Additionally, similar to many competitors in the space, these earbuds are non-repairable, which affects their overall score negatively.

Pros: Super microphone, unique design, excellent sound quality, reliable noise cancellation, comfortable fit, intuitive controls, Bluetooth 5.4 with multipoint support, cross-platform app options, and impressive battery life.

Cons: Non-repairable, higher cost than its predecessor, a fairly heavy case, the Super Mic doesn’t fully substitute for a dedicated mic, and noise cancellation struggles in high-noise settings.

The Nothing Ear 3 boasts attractive design features along with a couple of unique functionalities. Photo: Samuel Gibbs/The Guardian

Source: www.theguardian.com

Wegovy Improves Heart Health Even with Slight Weight Loss

Increasing evidence suggests that GLP-1 drugs like Wegovy offer benefits beyond treating obesity and type 2 diabetes.

Shelby Knowles/Bloomberg via Getty Images

Research indicates that the weight-loss medication Wegovy can lower the risk of heart attacks and other cardiovascular conditions, even in individuals who may not experience significant weight loss or those who aren’t severely obese.

Earlier findings from the SELECT trial hinted that Wegovy, a GLP-1 weight-loss drug, could have these heart health benefits, but it remained unclear if they were solely due to weight reduction. Studies involving pigs suggested a direct protective effect on the heart, now validated in humans.

“The important takeaway is that the cardiovascular advantages of these drugs occur independently of weight loss. This repositions them as drugs that modify diseases rather than merely aiding weight loss,” explains John Deanfield from University College London.

Wegovy contains semaglutide, a GLP-1 treatment, as well as Ozempic, which is designed for managing type 2 diabetes. While these treatments are approved for weight management and diabetes, they have shown promise in various other conditions, including dementia and alcoholism.

The SELECT trial assessed semaglutide against placebo regarding cardiovascular risks in 17,604 participants aged 45 and older who were overweight or obese. None were diabetic, yet all had some heart disease. In November 2023, Deanfield et al. announced that semaglutide reduced the likelihood of heart attacks, strokes, and other severe cardiac events by 20%.

Researchers are analyzing data to determine if these effects are solely due to weight loss, examining various body mass index (BMI) and weight loss ranges. They discovered that individuals starting with a BMI of 27—categorized as mildly obese—showed improved heart disease risk after using semaglutide, as did the severely obese with a BMI of 44.

Interestingly, the degree of weight lost seemed to have minimal impact on cardiovascular improvements, whether during the initial 20 weeks or throughout the nearly two-year study.

However, abdominal fat appears to play a significant role. Researchers noted that a slimmer waist at the study’s onset correlated with reduced heart disease risk, regardless of whether participants received semaglutide or a placebo. Moreover, after years on semaglutide, each 5-centimeter reduction in waist size was linked to a 9% decrease in cardiovascular event risk. The research team found that waistline reduction contributed to nearly one-third of the drug’s heart-protective effects, while the reasons for the other benefits remain unclear.

These results reinforce semaglutide’s potential beyond just weight management, as individuals in the placebo group even experienced a slight rise in heart disease risk while losing weight; this may be reflective of an underlying health issue, Deanfield notes.

Further studies are required to unpack how semaglutide and potentially other GLP-1 medications exert these benefits. Professor Deanfield speculates that enhancements in blood vessel function and blood pressure could be at play, alongside possible anti-inflammatory effects.

“Inflammation is a crucial mechanism influencing various diseases we want to avoid,” he mentions. “This appears to be a shared pathway targeted by these drugs.”

This advantage might also be linked to how semaglutide interacts with fat surrounding the heart, referred to as epicardial adipose tissue. Gianluca Iacobellis from the University of Miami highlights, “Semaglutide binds to epicardial adipose tissue receptors to enhance tissue health, consequently improving heart function and lowering cardiovascular event risks.”

“The query remains: What criteria should we establish to identify individuals most likely to benefit from these drugs?” questions Stefano Masi from the University of Pisa, Italy. “This is an ongoing challenge.”

topic:

  • Medical drugs /
  • heart disease

Source: www.newscientist.com

‘Enhanced’ CAR T-Cell Therapy Shows Potential in Treating Solid Tumors

Illustration of CAR T cell therapy targeting tumor cells

Illustration of CAR T cell therapy targeting tumor cells

Brainlight/Alamy

CAR T cells, which are immune cells modified to attack cancer, have transformed blood cancer treatments, particularly for leukemia. However, they have struggled against solid tumors. Recently, “weaponized” CAR T cells have successfully eliminated large prostate tumors in mice, providing optimism for similar therapies in humans.

“The tumor is completely gone,” states Jun Ishihara from Imperial College London, marking a unique achievement in animal research.

Our immune system typically identifies and destroys many cancers early on. Cancer cells often display mutated proteins recognized by T cells, which seek to eliminate these threats using surface receptor proteins, functioning similarly to antibodies.

However, not every cancer incites an immune response. In the 1980s, scientists found a way to engineer T cells to target cancer more effectively by incorporating genes for chimeric antigen receptors, hence the term CAR T.

While CAR T cells have shown remarkable success in treating some blood cancers, they also carry significant risks. They are effective for some but not all patients, and ongoing enhancements are needed. The development of CRISPR gene editing facilitates further improvements to these therapies.

Despite advancements, CAR T therapies remain ineffective for most solid tumors due to two primary challenges: the vast heterogeneity of solid tumors—where not all cells present the same mutated proteins—and the tumors’ ability to evade immune responses by emitting “do not attack” signals.

Researchers have attempted to enhance CAR T cells by incorporating immune-boosting proteins like interleukin-12, but this has sometimes resulted in overwhelming immune responses that damage healthy tissues.

Ishihara and colleagues have pioneered a method to localize interleukin-12 specifically to tumors. By fusing interleukin-12 to a protein that binds collagen, which is prevalent in tumors, they engineered it to target the exposed collagen found in both wounds and tumors. “Tumors are rich in collagen and are dense because of it,” Ishihara noted.

The modified CAR T cells produce this fusion protein when they bind to the mutated proteins present in certain prostate cancers. Once released, the fusion protein attaches to the tumor’s collagen, effectively signaling the immune system to launch an attack.

Trial results were promising, as the treatment eradicated 80% of large prostate tumors in the test mice. Additionally, when exposed to cancer cells afterward, no new tumors formed, indicating a robust immune response from the CAR T cells.

Remarkably, this approach did not necessitate preconditioning. Usually, chemotherapy is given to create space for new CAR T cells by depleting existing immune cells, risking side effects such as infertility. “We were surprised that no chemotherapy was required,” says Ishihara. His team aspires to commence human clinical trials within the next two years.

“This is a promising avenue that warrants clinical testing,” stated Stephen Albelda from the University of Pennsylvania. He noted that numerous research groups are also exploring similar methods for tumor-targeted localization of interleukin-12, with encouraging results being reported.

topic:

Source: www.newscientist.com

New Research Uncovers How Reptiles Excrete Crystalline Waste in Large Quantities

Both avian and non-avian reptiles eliminate excess nitrogen as solid compounds known as “urate,” an evolutionary trait that aids in water conservation. Despite this adaptation, numerous questions regarding the composition, structure, and assembly of these biological materials remain unresolved. In a recent study, researchers from Georgetown University, the International Diffraction Data Center, Chiricahua Desert Museum, and Georgia State University investigated uric acid excretion in the desert. They focused on the ball python (python) along with 20 other reptile species, aiming to uncover efficient and versatile mechanisms for processing both nitrogenous waste and salts.

Thornton et al. investigated the solid urine of over 20 reptile species. Image credit: Thornton et al., doi: 10.1021/jacs.5c10139.

“All living organisms possess some form of excretory system. After all, what enters must eventually exit,” says the chemist from Georgetown University, Jennifer Swift, along with her colleagues.

“In humans, we eliminate excess nitrogen primarily through urine in the forms of urea, uric acid, and ammonia.”

“Conversely, many reptiles and birds efficiently package these nitrogenous compounds into solids, specifically urates, which are excreted through their cloaca.”

Scientists theorize that this process may have evolved to aid in water conservation.

“While crystallizing waste fluids may provide an evolutionary benefit for reptiles, it poses significant challenges for humans,” the researchers noted.

“Excess uric acid in the human body can crystallize in the joints, leading to painful conditions like gout, or form kidney stones in the urinary tract.”

In this recent study, the authors examined urate from over 20 reptile species to understand how these animals safely eliminate crystalline waste.

“Our research stems from a curiosity about how reptiles safely process this substance, and we hope it could inform new approaches to disease prevention and treatment,” Dr. Swift commented.

Microscopic analyses revealed that three species—the ball python, Angora python, and Madagascar tree boa—produce urate consisting of microscopically textured microspheres ranging from 1 to 10 micrometers in diameter.

X-ray examinations indicated that these spheres are comprised of even smaller nanocrystals of uric acid and water.

Furthermore, scientists have found that uric acid plays a crucial role in transforming ammonia into a less harmful solid state.

They hypothesize that uric acid may serve a similar protective function in humans.

“Our investigation of urate produced by various squamate reptiles sheds light on the sophisticated and adaptable systems they employ for managing nitrogenous wastes and salts,” the researchers stated.

“Understanding how dietary habits, environmental conditions, and aging impact sample analysis—along with advancements in instrumentation—offers a more comprehensive insight into the structure and function of biological urates.”

“The specifics of where and how these microspheres are created remain an intriguing question, yet their presence across different uric acid globule species suggests that this low-energy process is optimized under similar selective pressures.”

“Recognizing the role of uric acid in ammonia management could have significant implications for human health, although clinical research is required to verify this hypothesis.”

For further information, refer to the findings published today in the Journal of the American Chemical Society.

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Alyssa M. Thornton et al. Uric acid monohydrate nanocrystals: an adaptable platform for nitrogen and salinity management in reptiles. J. Am. Chemistry Society published online October 22, 2025. doi: 10.1021/jacs.5c10139

Source: www.sci.news

New Research Indicates Australia’s First Inhabitants Were Fossil Collectors

In a recent study, Professor Mike Archer from the University of New South Wales and his team revisited the fossilized tibia (the lower leg bone) of the now-extinct giant stenurine kangaroo. These bones, discovered in Mammoth Cave in southwestern Australia around World War I, provided solid evidence that Indigenous Australians hunted large animals, a finding in which Professor Archer was involved. A 1980 study had concluded that distinctive notches in the fossilized bones indicated slaughter. However, Professor Archer is now ready to acknowledge that this initial conclusion was incorrect.



Giant animal unearthed from mammoth cave about 50,000 years ago: giant long-beaked echidna Malayanglossus hackettii, giant kangaroo Procoptodon brauneorum, giant diprotodont Zygomaturus trilobus, and possum (Thylacinus cynocephalus). Image credit: Peter Schouten.

“As a scientist, updating the record as new evidence emerges is both my duty and responsibility,” Professor Archer stated.

“In 1980, we interpreted those cuts as signs of slaughter based on the best conclusions we could reach with the tools available to us then.”

“With advancements in technology, we now understand that our original interpretation was incorrect.”

“After the 1960s, there was a significant debate about whether Aboriginal peoples coexisted with Australia’s prehistoric megafauna or contributed to their extinction.”

“Many believed the incisions in the bones were made by humans using tools, suggesting that the extinction of megafauna and the arrival of humans approximately 65,000 years ago were not coincidental.”

“For decades, the bones from Mammoth Cave were seen as the ‘smoking gun’ indicating that Indigenous Australians hunted giant animals, but with that evidence dispelled, the discussion on megafauna extinction is now reopened, and the role of humans is more ambiguous than ever.”

To reexamine the same dissected stenurine leg bone, Professor Archer and his co-authors utilized advanced 3D scanning technology to analyze the bone without causing any damage.

They also employed modern radiometric dating methods to accurately determine the age of the bones and their cut surfaces while conducting detailed microscopic examinations.

Their findings indicated that the cuts were made after the bone had dried and cracked, suggesting the bones were likely already fossilized when the incisions occurred.

Paleontologists also investigated a fossilized tooth given to archaeologist Kim Ackerman by a Wora man from the Mowanjum mission, who had collaborated with Indigenous communities in the Kimberley during the 1960s.

This tooth, belonging to the Zygomaturus trilobus, a species of giant marsupial related to wombats, was part of Australia’s Pleistocene megafauna.

The tooth was retrieved from the Kimberley in northwestern Australia, and its characteristics closely matched other fossils found in Mammoth Cave in southwestern Australia.

Dr. Kenny Trabouillon from the Western Australian Museum remarked, “The discovery of this tooth in the Kimberley, far from its likely origin in Mammoth Cave, implies it may have been transported or traded by humans across great distances.”

“This suggests that cultural appreciation and symbolic usage of fossils existed long before the advent of European science.”

“The First Peoples might have been the continent’s, and possibly the world’s, earliest paleontologists.”

Researchers haven’t entirely dismissed the possibility of Aboriginal people having hunted Australia’s megafauna.

However, without concrete evidence, we cannot definitively assert that Indigenous Australians caused its extinction.

“While these remain hypotheses, we need substantiated proof before concluding that predation by Indigenous peoples contributed to the extinction of now-vanished megafauna, especially considering the long history of Indigenous peoples respecting and sustainably utilizing Australia’s wildlife,” Professor Archer stated.

“If humans were truly responsible for the unsustainable hunting of Australia’s megafauna, we would expect to find much more evidence of such hunting in the fossil record. Instead, the only solid evidence we had until now was this single bone, which now shows strong indications that the mutilations occurred post-mortem.”

If humans were not solely accountable for the extinction of Australia’s ancient megafauna, then what was?

Researchers indicate that many megafauna species went extinct long before humans arrived, and while some coexisted with humans for millennia, their decline often aligned with significant climate changes.

“What we can ascertain is that the First Peoples were the first in Australia to exhibit a keen interest in and collect fossils, likely thousands of years before Europeans arrived on the continent,” the researchers affirmed.

Their paper was published in the journal Royal Society Open Science.

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Michael Archer et al. 2025. Australia’s first people: hunters of extinct megafauna or Australia’s first fossil collectors. R. Soc. Open Science 12(10):250078; doi: 10.1098/rsos.250078

Source: www.sci.news

Physicists Suggest a Cosmic ‘Knot’ Could Have Influenced the Early Universe Briefly

Knots are prevalent in various fields of mathematics and physics today. A collaborative team of Japanese and German physicists proposes the existence of a “knot-dominated epoch” in the universe’s early days, suggesting that knots were essential building blocks during this time. This intriguing hypothesis can be investigated through gravitational wave observations. Additionally, they theorize that the conclusion of this period will involve the collapse of the knot due to quantum tunneling, leading to an Asymmetry between matter and antimatter in space.



Model proposed by Eto et al.. It suggests a brief, knot-dominated epoch when these intertwined energy fields outweighed everything else, a scenario that can be investigated through gravitational wave signals. Image credit: Muneto Nitta / Hiroshima University.

Mathematically, knots are defined as closed curves embedded in three-dimensional space and can be found not just in tying neckties but across numerous scientific disciplines today, as noted by Lord Kelvin.

Although his theory postulated that atoms are knots of etheric vortices was ultimately refuted, it sparked advancements in knot theory and its application in multiple areas of physics.

“Our study tackles one of the core mysteries of physics: why the universe is predominantly composed of matter rather than antimatter,” remarked Professor Munehito Nitta, a physicist at Hiroshima University and Keio University.

“This question is crucial as it relates directly to the existence of stars, galaxies, and ourselves.”

“The Big Bang was expected to produce equal amounts of matter and antimatter, with the intent that each particle would annihilate its counterpart, leaving only radiation.”

“Yet, the universe is overwhelmingly composed of matter, with only trace amounts of antimatter.”

“Calculations indicate that to achieve the matter we see today, only one extra particle of matter is needed for every billion matter-antimatter pairs.”

“Despite its remarkable achievements, the Standard Model of particle physics fails to resolve its inconsistencies.”

“That prediction is significantly off.”

“Unraveling the origin of the slight excess of matter, a phenomenon known as baryogenesis, remains one of the greatest unresolved enigmas in physics.”

By merging the measured baryon number minus lepton number (BL) symmetry with the Peksey-Quinn (PQ) symmetry, Professor Nitta and his associates demonstrated that the knot could have spontaneously formed in the early universe, resulting in the observed surplus.

These two well-studied extensions to the standard model address some of its most confounding gaps.

PQ symmetry offers a solution to the strong CP problem, which explains the absence of the small electric dipole moments that theories predict for neutrons, simultaneously introducing axions, a leading candidate for dark matter.

BL symmetry, conversely, elucidates why neutrinos, elusive particles that can seamlessly pass through entire planets, possess mass.

Maintaining the PQ symmetry globally, rather than merely measuring it, safeguards the delicate axion physics that addresses the strong CP problem.

In physics, “measuring” a symmetry implies allowing it to operate freely at any locale and moment in time.

However, this regional freedom requires nature to introduce new mechanisms for force transmission to clarify the equations.

By acknowledging BL symmetry, the researchers not only validated the existence of heavy right-handed neutrinos (crucial for averting anomalies in the theory and central to the primary burr formation model) but also incorporated superconducting behavior, likely providing the magnetic foundation for some of the universe’s earliest knots.

As the universe cooled following the Big Bang, its symmetry may have fractured through a series of phase transitions, leaving behind string-like defects called cosmic strings, which some cosmologists theorize may still persist.

Even though thinner than a proton, a cosmic string can stretch across a mountain.

As the universe expanded, these writhing filaments would twist and intertwine, preserving traces of the primal conditions that once existed.

The breakdown of BL symmetry formed a flux tube string, while PQ symmetry resulted in a flux-free superfluid vortex.

This contrast renders them compatible.

The BL flux tube grants the Chern-Simons coupling of the PQ superfluid vortex a point of attachment.

This coupling subsequently channels the PQ superfluid vortex into the BL flux tube, counteracting the tension that might otherwise disrupt the loop.

The outcome is a metastable, topologically locked structure known as a knot soliton.

“No prior studies had simultaneously considered these two symmetries,” notes Professor Nitta.

“In a way, our good fortune lay in this. By integrating them, we uncovered a stable knot.”

While radiation diminishes energy as waves traverse through space and time, knots exhibit properties akin to matter and dissipate energy far more gradually.

They subsequently surpassed all other forms, heralding an era of knot domination, where their energy density eclipsed that of radiation in the universe.

However, this dominance was short-lived. Ultimately, the knot succumbed to quantum tunneling, an elusive process where particles slip through energy barriers as though they were nonexistent.

This decay yielded heavy dextral neutrinos, a consequence of the inherent BL symmetry within its framework.

These colossal, elusive particles eventually transformed into lighter and more stable variations that favored matter over antimatter, shaping the universe we recognize today.

“Essentially, this decay releases a cascade of particles, including right-handed neutrinos, scalar particles, and gauge particles,” explained Dr. Masaru Hamada, a physicist at the German Electron Synchrotron Institute and Keio University.

“Among them, right-handed neutrinos are particularly noteworthy since their decay can inherently generate a discrepancy between matter and antimatter.”

“These massive neutrinos decompose into lighter particles, such as electrons and photons, sparking a secondary cascade that reheats the universe.”

“In this manner, they can be regarded as the ancestors of all matter in the universe today, including our own bodies, while knots might be considered our forebears.”

Once the researchers delved into the mathematics underlying the model—analyzing how efficiently the knot produced right-handed neutrinos, the mass of those neutrinos, and the degree of heat generated post-collapse—the observed matter-antimatter imbalance naturally emerged from their equations.

Rearranging the equations, with an estimated mass of 1012 gigaelectronvolts (GeV) for heavy dextral neutrinos, and assuming that most energy retained by the knot was utilized to generate these particles, the model yielded a natural reheating temperature of 100 GeV.

This temperature fortuitously coincides with the final opportunity for the universe to produce matter.

Should the universe cool beyond this point, the electroweak reactions that convert neutrino discrepancies into matter would cease permanently.

Reheating to 100 GeV may have also reshaped the cosmic gravitational wave spectrum, shifting it toward higher frequencies.

Forthcoming observatories such as Europe’s Laser Interferometer Space Antenna (LISA), the United States’ Cosmic Explorer, and Japan’s Decihertz Interferometer Gravitational-Wave Observatory (DECIGO) may someday detect these subtle tonal variations.

Dr. Minoru Eto, a physicist at Yamagata University, Keio University, and Hiroshima University, remarked, “The cosmic string is a variant of topological soliton, an entity defined by a quantity that remains unchanged regardless of how much it is twisted or stretched.”

“This characteristic not only guarantees stability but also indicates that our results are not confined to the specifics of the model.”

“While this work is still theoretical, we believe it represents a significant advancement towards future development, as the foundational topology remains constant.”

Although Lord Kelvin initially proposed that knots were fundamental components of matter, the researchers assert that their findings present the first realistic particle physics model in which knots could significantly contribute to the origin of matter.

“The next step involves refining our theoretical models and simulations to more accurately forecast the formation and collapse of these knots, connecting their signatures with observable signals,” said Professor Nitta.

“In particular, upcoming gravitational wave experiments like LISA, Cosmic Explorer, and DECIGO will enable the testing of whether the universe indeed experienced a knot-dominated era.”

The team’s work appears in the journal Physical Review Letters.

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Minoru Eto et al. 2025. Tying the Knot in Particle Physics. Physics. Pastor Rhett 135, 091603; doi: 10.1103/s3vd-brsn

Source: www.sci.news

High-Definition Video with Low Energy Consumption on Color E-Paper Screens

Gustav Klimt’s The Kiss presented on an iPhone (left) alongside a smaller e-paper display (right) showing the same artwork

Kingston Frameworks; Kunli Xiong et al. (2025)

A groundbreaking type of color e-paper is capable of showcasing vivid, high-resolution, full-color images and videos with minimal power consumption, heralding a potential new era for display technologies.

Unlike conventional LED screens, which produce colors through the emission of red, green, and blue light, e-paper screens utilize small molecules to generate images. Historically, these screens were restricted to black and white, but advancements have now allowed for color displays. However, they still face challenges in updating quickly enough for video playback.

To address this issue, Kunli Shion and their team at Uppsala University in Sweden have engineered electronic paper featuring pixels constructed from tungsten oxide nanodisks. Each pixel measures roughly 560 nanometers, resulting in an impressive resolution of 25,000 pixels per inch (PPI), whereas typical smartphone displays generally have resolutions in the hundreds.

The tungsten oxide nanodiscs are designed in various sizes and spacings to reflect distinct bands of light. By arranging them together, a range of colors can be created, with brightness adjustable through short electrical pulses that position ions within each disk. Once set, these ions maintain their placement, allowing the color to persist without a continuous power source.

The researchers constructed an e-paper display that measures just 1.9mm by 1.4mm, roughly 1/4000 the size of a conventional smartphone display, and utilized it to showcase a 4300×700 pixel segment of Gustav Klimt’s The Kiss – achieving remarkable resolution for such a compact device. It is also capable of refreshing approximately every 40 milliseconds, making it suitable for video display.

Another significant advantage of this novel e-paper technology is its remarkably low energy consumption, as noted by Xiong. The display utilizes about 1.7 milliwatts per square centimeter for video and around 0.5 milliwatts per square centimeter for still images.

“What I find impressive about this development is its capacity to support video at a rapid pace while consuming minimal energy, as each element remains switched after being activated,” comments Jeremy Baumberg from Cambridge University.

Topics:

Source: www.newscientist.com

Gene-Edited Pigs Resistant to Swine Fever: A Potential Advancement for Animal Welfare

Gene-edited pigs exhibit resistance to swine fever

Simon Lillico

By making a few genetic modifications, pigs can be rendered entirely resistant to swine fever, a significant issue for farmers globally. This gene editing could also confer resistance to related viruses in cattle and sheep.

The widespread adoption of gene-edited pigs resistant to swine fever is expected to enhance animal welfare, boost productivity, reduce greenhouse gas emissions, and lower retail prices. “This will foster sustainable livestock production and promote the well-being of pigs,” asserts Helen Crook from the UK Animal and Plant Health Agency.

Swine fever is a highly contagious viral illness that can lead to symptoms ranging from fever to diarrhea and miscarriage, often resulting in significant pig mortality.

While the disease has been eliminated in many regions, it can resurface. For instance, in 1997, the Netherlands culled 6 million pigs to contain an outbreak, and Japan has faced ongoing challenges since 2018.

Typically, when outbreaks occur, livestock are protected using vaccines containing live, weakened virus strains, which is a complex and costly process. “Vaccination demands extensive coordination and oversight,” mentions Christine Tate-Burkard from the University of Edinburgh, UK.

Countries utilizing vaccinations face restrictions when exporting to disease-free areas. Interruptions in vaccination programs can also lead to outbreaks, as seen recently in the Philippines, explains Tate-Burkard.

Nevertheless, the classic swine fever virus has a vulnerability. The viral protein bundles formed from long chains of amino acids must be cleaved into functional pieces, relying on specific pig proteins for this process.

By altering a single amino acid in this pig protein, referred to as DNAJC14, it may be possible to obstruct this cleavage. Tait-Burkard and colleagues employed CRISPR gene editing to create pigs with this minor modification.

Subsequently, the team sent some of these pigs to a secure facility, where Crook’s group introduced the live swine virus intranasally. All typical pigs fell ill, while the gene-edited pigs showed no signs of infection. There were no symptoms, antibodies, nor detectable virus.

“These pigs demonstrated complete resistance to viral replication and remained healthy and content throughout the experiment,” states Crook.

This research was partially sponsored by Genus, a major international breeding company currently evaluating the commercialization of these pigs.

Genus has previously developed gene-edited pigs resistant to another significant disease, porcine reproductive and respiratory syndrome, which are already approved in the United States, Brazil, and other nations. The company awaits approvals in Mexico, Canada, and Japan—key export markets for the U.S.—before it can start selling semen to farmers.

When used to implement small changes that can naturally occur, gene editing often faces less stringent regulations compared to traditional genetic engineering. Japan has already sanctioned three types of gene-edited fish.

The UK is anticipated to begin approving gene-edited plants soon, although regulations for livestock are yet to be finalized. It is expected that these regulations will prioritize animal welfare.

The research team observed no adverse effects in the swine fever-resistant pigs, according to Simon Lillico and colleagues from the University of Edinburgh, although further research is necessary to confirm these findings.

He emphasizes that traditional breeding lacks such welfare considerations. “It would be beneficial to ensure a level playing field,” he remarks. “We are aware that some conventionally reared animals experience low welfare standards.”

A virus closely related to classical swine fever is responsible for causing bovine viral diarrhea in cattle and borderline disease in sheep. While these diseases are not lethal, they still impact welfare and productivity. The Edinburgh research team is presently examining whether modifications made to pigs will also benefit cattle and sheep.

Topics:

Source: www.newscientist.com

I Discovered a Love for Fitness with This Game-Changing App

For much of my life, I had a strong aversion to exercise. Each time I tried a new fitness plan, I succumbed to monotony and laziness. My gym membership gathered dust, and my home workout equipment lay unused. The only time I managed to maintain a consistent workout routine was with a personal trainer, but at hundreds of dollars an hour in my area, that wasn’t a sustainable option.


For the past three years, I have been using Future Fitness, which has proven to be the next best alternative. This app and membership connects you with actual trainers who personalize your workout regimen and keep you accountable just like an in-person trainer would. While it costs $199/month, which isn’t cheap, it’s the only fitness app that has truly worked for me, making it worth the investment. Here’s why:


Get Into Gear

I first noticed Future Fitness on my Instagram feed early in the pandemic, promoting a free trial. Having gained a bit of weight from inactivity, I figured it was worth a shot. The app prompted me with questions about my goals and fitness habits, then allowed me to select a coach from several available options.

Photo: Provided by Future Fitness

During a preliminary FaceTime call with my chosen coach, we explored my overall fitness aspirations, preferred training schedule, any existing injuries, and the equipment I had access to at home. I’ve gathered a list of the gear I’ve utilized thus far: a yoga mat, resistance bands, two sets of dumbbells, two kettlebells, a suspension trainer, and a Peloton bike. Future coaches can work with whatever equipment you possess, even if you have none.


There is one exception; you will likely need a smartwatch. While it’s not strictly necessary, having one significantly enhances your experience with the app. The smartwatch syncs with the Future app, allowing you and your coach to monitor key details such as your heart rate during workouts and daily activity levels. The watch counts your repetitions for specific exercises, like bicep curls and deadlifts, in addition to tracking spontaneous activities such as extended hikes. I used my Apple Watch, but Future is also compatible with selected Google Wear OS watches.

Hit the Weights

Photo: Provided by Future Fitness

After our initial consultation, my coach began sending me workout routines via the app, complete with video demonstrations and pre-recorded tips for maintaining proper form. Alongside these strength training sessions, my Future coach can incorporate additional exercises throughout the week if desired. For instance, on days without strength training, I was directed to use my Peloton bike.

Each workout routine typically consists of a quick warm-up, a series of varied exercises, followed by a cool-down. The videos demonstrate how to execute each movement with multiple camera angles and explicit instructions. Strangely enough, I found this clinical method more appealing than the overly enthusiastic styles of many YouTube personalities or loud Peloton music.

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However, not everything is straightforward. Initially, some workouts proved to be overly challenging. An in-person trainer could adjust my routine on the fly, but I had to adapt on my own in this case. Thankfully, after reaching out to my coach, she offered alternative exercises (like knee push-ups instead of standard ones) and encouraged me to listen to my body’s needs.

Photo: Provided by Future Fitness

My coach excels at keeping me accountable. Each morning, she messages me to remind me of that day’s workout. My Apple Watch transmits my workout information to her, ensuring transparency. If I take a rest day, she prompts me to refocus. After reviewing my workout stats, she messages me to congratulate me on my efforts and asks for my feedback. This ongoing dialogue with my coach is a significant factor in my ability to adhere to my fitness routine.

I paused my Future Fitness membership due to financial constraints, but I am currently several months into reinvigorating my subscription, and I feel fantastic. My joints ache less, I have more energy throughout the day, and my overall mental well-being has improved. These days, I work out five days a week, up from three initially. It seems I don’t actually dislike exercise after all.

Future Fitness for $199/month

  • Nicole Lee is a technology journalist with over 20 years of experience covering consumer electronics, social media, kitchen technology, and more. She has also made media appearances on broadcast television and public radio. Outside of work, her passions include baseball, improv comedy, and tabletop role-playing games.

Source: www.theguardian.com

Google Unveils Quantum Computers’ Ability to Unlock Molecular Structures

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Google’s Quantum Computing Willow Chip

Google Quantum AI

Researchers at Google Quantum AI have leveraged Willow quantum computers to enhance the interpretation of data sourced from nuclear magnetic resonance (NMR) spectroscopy—an essential research method within chemistry and biology. This significant advancement may open new horizons for the application of quantum computing in various molecular technologies.

While quantum computers have been most effectively demonstrated in cryptographic contexts, current devices face limitations in scale and error rates that hinder their competence in decryption tasks. However, they show promise in expediting the discovery of new drugs and materials, which align with the fundamentally quantum nature of many scientific procedures. Hartmut Neven and colleagues at Google Quantum AI have showcased one instance where quantum computers can mimic the complex interactions found in natural processes.

The investigation centered on a computational method known as quantum echo and its application to NMR, a technique utilized to extract detailed information regarding molecular structures.

At its core, the concept of quantum echoes is akin to the butterfly effect. This phenomenon illustrates how minor perturbations—like the flap of a butterfly’s wings—can trigger substantial changes in broader systems. The researchers exploited a quantum approach within a system made up of 103 qubits in Willow.

During the experiment, the team executed a specific sequence of operations to alter the quantum state of a qubit in a manageable way. They then selected one qubit to disrupt, acting as a “quantum butterfly,” and employed the identical sequence of operations, effectively reversing time. Finally, the researchers evaluated the quantum characteristics of the qubits to extract insights regarding the entire system.

In a basic sense, the NMR technique applied in the lab also hinges on minor disturbances; it nudges actual molecules using electromagnetic waves and examines the system’s reactions to ascertain atomic positions—similar to using a molecular ruler. If the operations on qubits can replicate this process, the mathematical scrutiny of the qubits can likewise be translated into molecular structural details. This series of quantum computations could potentially enable the examination of atoms that are relatively distant from one another, said team member Tom O’Brien. “We’re constructing longer molecular rulers.”

The researchers believe that a protocol akin to quantum echoes would require approximately 13,000 times longer on a conventional supercomputer. Their tests indicated that two distinct quantum systems could successfully perform a quantum echo and yield identical outcomes—a notable achievement given the inconsistencies faced in previous quantum algorithms supported by the team. O’Brien noted that enhancements in the quality of Willow’s hardware and reduced qubit error rates have contributed to this success.

Nonetheless, there remains ample opportunity for refinement. In their utilization of Willow and quantum echoes for two organic molecules, the researchers operated with a mere 15 qubits at most, yielding results comparable to traditional non-quantum methods. In essence, the team has not yet demonstrated a definitive practical edge for Willow over conventional systems. This current exhibition of quantum echo remains foundational and has not been subjected to formal peer review.

“Addressing molecular structure determination is crucial and pertinent,” states Keith Fratus from HQS Quantum Simulations, a German company focused on quantum algorithms. He emphasizes that bridging established techniques such as NMR with calculations executed by quantum computers represents a significant milestone, though the technology’s immediate utility might be confined to specialized research in biology.

Doris Sels, a professor at New York University, remarked that their team’s experiments involve larger quantum computers and more complex NMR protocols and molecules than prior models. “Quantum simulation is often highlighted as a promising application for quantum computers, yet there are surprisingly few examples with industrial relevance. I believe model inference of spectroscopic data like NMR could prove beneficial,” she added. “We’re not quite there, but initiatives like this inspire continued investigation into this issue.”

O’Brien expressed optimism that the application of quantum echo to NMR will become increasingly beneficial as they refine qubit performance. Fewer errors mean a greater capability to execute more operations simultaneously and accommodate larger molecular structures.

Meanwhile, the quest for optimal applications of quantum computers is ongoing. While the experimental implementation of quantum echoes on Willow is remarkable, the mathematical analysis it facilitates may not achieve widespread adoption, according to Kurt von Keyserlingk at King’s College London. Until NMR specialists pivot away from traditional methods cultivated over decades, he suggests that its primary allure will lie with theoretical physicists focused on fundamental quantum system research. Furthermore, this protocol may face competitive challenges from conventional computing methods, as von Keyserlingk has already pondered how traditional computing might rival this approach.

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Source: www.newscientist.com

The serum stimulates hair growth by imitating skin irritation effects.

Eczema-like stimulation promoted hair regrowth in shaved mice over 20 days (bottom row). Meanwhile, hair growth was notably less in shaved mice lacking this stimulation (top row).

Tai et al. 2025

Skin inflammation can encourage hair growth in mice by activating fat cells. The serum derived from this process may also benefit humans without causing discomfort.

While hair loss is often addressed with medications or steroid injections, more effective solutions are being researched, including stem cell therapies and drugs that reactivate dormant hair follicles.

Songjian Lin, among researchers at National Taiwan University, became intrigued by how adipose tissue influences hair growth during experiments with mice. “Unexpectedly, we found changes in the size of fat cells following skin inflammation. [Fat cells] shrink quickly before hair starts to grow back. We proposed that fat cells could release fatty acids via lipolysis to spur hair regeneration,” Lin explains.

To explore this further, they repeated the study and examined the relevant cells more closely. They initially applied an irritant to a shaved section of the mouse’s back to simulate eczema. By day ten, they noted that the mice’s hair follicles were actively growing, resulting in visible hair growth in those regions. This effect was absent in other shaved areas without eczema, as well as in control mice.

The research team observed that this phenomenon appears to occur because immune cells called macrophages migrate to the fat layer beneath the mouse’s skin, signaling fat cells to release fatty acids. These fatty acids are then utilized by hair follicle stem cells, promoting increased mitochondrial production, which supplies energy and fosters hair growth. This aligns with past studies indicating that plucking hair can trigger immune responses in nearby hair follicles, stimulating their growth.

Though eczema isn’t typically linked to hair growth in humans, other forms of skin inflammation may play a role, such as those associated with casts for broken bones, which are connected to excess hair growth.

Next, Lin and his team sought to determine whether fatty acids alone could induce hair growth without prior irritation. They formulated a serum containing various fatty acids dissolved in alcohol. This serum was applied to non-irritated shaved mice, and the results were compared to untreated areas and control mice. “We discovered that only monounsaturated fatty acids, like oleic acid and palmitoleic acid—prevalent in adipose tissue—successfully induced hair regrowth when applied topically,” Lin notes.

The researchers, who have since patented the serum, also observed encouraging outcomes when tested on human hair follicles in the lab and now intend to evaluate different dosages on human scalps.

Lin does not anticipate any serious side effects from the treatment. “Oleic acid and palmitoleic acid are naturally occurring fatty acids. They are present in high quantities in our fat tissue and various vegetable oils, making them safe for use,” he states. “I applied a solution of these fatty acids mixed with alcohol to my thighs for three weeks and noticed it stimulated hair growth.”

However, he cautions that the treatment hasn’t yet undergone testing on human skin, and animal models may differ significantly, especially concerning hair follicle biology. Christos Tziotsios from King’s College London also points out that similar serums are under development, including one utilizing plant extracts that promote hair growth in a matter of weeks.

Nonetheless, Tziotsios affirms that the latest findings enhance our comprehension of hair growth and loss. “We were aware of fat cells’ involvement in hair follicle formation, but this is the first instance we’ve witnessed them playing a role in hair regeneration,” he remarks. It could also clarify why certain individuals experience hair growth post-microneedling treatments, which involve rolling fine needles across the scalp to create micro-injuries that elicit an immune response.

Source: www.newscientist.com

Unveiling the Reality Behind F1’s New ‘Sustainable’ Fuel and Its Impact on Future Cars

In the upcoming year, Formula 1 (F1) is set to undertake one of its most ambitious transformations yet, shifting from fossil fuels to a fully sustainable fuel mixture. This initiative is part of a broader strategy to adhere to new environmental regulations and demonstrate that the sport can, as F1 puts it, “continue without the need for new car production”.

Nonetheless, skepticism remains. As F1 contributes over 1% of the total carbon footprint in sports, experts argue that there are far more significant environmental issues that F1 must address. What are these challenges and how can we overcome them?

Switch Gears

In 2020, F1’s governing body, the Fédération Internationale de l’Automobile (FIA), established a timeline for race car engines to transition to 100% sustainable fuel by 2026 and achieve carbon neutrality by 2030.

From 2023 to 2024, Formula 2 and Formula 3, F1’s supporting racing series, will start utilizing 55% ‘sustainable bio-based fuels’, transitioning to 100% ‘advanced sustainable fuels’ by 2025.

F1 has developed its own ‘sustainable’ fuel for 2026, designed specifically for the hybrid engines currently used in F1 cars, which consist of both an internal combustion engine (ICE) and two electric motor generators.

Images from the Japanese Grand Prix, which was rescheduled from autumn to spring to minimize carbon emissions related to equipment transport between races (Source: Formula 1) – Formula 1

According to F1, the new fuel will not raise the overall carbon levels in the atmosphere. The carbon used in these new fuels will be sourced from existing materials, such as household waste and non-food biomass, or it will be captured directly from atmospheric carbon dioxide.

This will enable the production of synthetic fuels, which are man-made fuels aimed at replacing the fossil fuel-based gasoline currently in use. In the long term, the FIA asserts that F1, 2, and 3 will all eventually adopt this “fully synthetic hybrid fuel”.

Moreover, this new fuel will be classified as “drop-in”, indicating that it will be compatible with existing internal combustion engines as well as the current fuel distribution infrastructure. This means the fuel powering F1 cars in 2026 will be the same fuel you could purchase at your local gas station today.

Is it Truly Sustainable?

However, as the term “sustainable” has gained popularity, experts have started to challenge F1’s assertions.

Dr. Paula Pérez-López, an expert in environmental and social sustainability at the MINES ParisTech Center for Observation, Impacts, and Energy (OIE), articulates that for a product to qualify as “sustainable”, it must fulfill certain environmental, social, and economic criteria, with each segment of the supply chain considering these factors.

“The term ‘sustainable’ should not be confused with ‘low carbon’. A product or process may exhibit low carbon emissions but still produce high levels of other pollutants, thus rendering it ‘unsustainable’. “

The FIA’s collaboration with the Zemo partnership, a UK-based nonprofit organization, has led to the introduction of the Sustainable Racing Fuel Assurance Scheme (SRFAS). This third-party initiative ensures that sustainable racing fuels comply with FIA regulations.

The certification mandates that the fuel comprises “at least 99 percent Advanced Sustainable Components (ASC)” that are certified to be derived from renewable energy sources such as non-biological origin (RFNBO), municipal waste, or non-food biomass.

Essentially, this means that the new fuel must be synthetic, produced from waste, or derived from materials not intended for human or animal consumption, such as specially engineered algae.

New fuels must also adhere to criteria such as the EU Renewable Energy Directive III (RED III) along with EU Delegated Law.

Fraser Browning, the founder of Curve Carbon, which advises companies on minimizing their environmental footprints, indicates that these new fuels can indeed facilitate genuine decarbonization efforts if managed appropriately.

“The overarching question pertains to F1’s complete impact,” he notes. “Is F1 pursuing synthetic fuels as a vital component of their sustainability goals, or is it merely a procedural formality?”

Browning emphasizes that advancements in motorsport have historically contributed to significant innovations in sustainable transportation. For instance, in 2020, Mercedes announced that hybrid technology would be utilized in road cars. Earlier this year, they also revealed a new battery technology capable of extending the range of electric vehicles by 25 percent.

“Without the innovations deriving from motorsport, hybrid vehicles wouldn’t have evolved at the present speed,” he contends. “However, this needs to be executed transparently and responsibly.”

Cutting Carbon

Beyond the transition to synthetic fuels, F1 is also making strides to reduce carbon emissions in other areas. Travel and logistics account for roughly two-thirds of F1’s carbon emissions, as teams, heavy machinery, and fans travel considerable distances between races each year.

To mitigate this, adjustments have been made to the F1 calendar for 2024 to lessen freight distances between events, as stated in F1’s latest Impact Report. For example, the Japanese Grand Prix has been synchronized with other Asia-Pacific races and moved to April.

Formula 1 has unveiled that DHL’s new fleet of biofuel-powered trucks minimizes carbon dioxide emissions by an average of 83% compared to traditional fuel-powered trucks during the European segment of the 2023 season (Source: F1) – Formula 1

Additionally, F1 has broadened the adoption of biofuels for the trucks used to transport equipment throughout Europe, resulting in a 9% reduction in logistical carbon emissions.

By the conclusion of 2024, total carbon emissions are projected to decrease by 26% from 2018 levels, although F1 acknowledges there remain “key milestones to achieve, including further investments in alternative fuels and updates to our logistics system to enhance efficiency”.

Synthetic Fuels vs. Electric Vehicles

What does it mean when F1 claims that its new synthetic fuel is a drop-in solution suitable for everyday vehicles? Could it serve as a more sustainable alternative to electric vehicles (EVs)?

Critics warn that producing synthetic fuels for internal combustion engines (ICE) is energy-intensive, costly, and may require five times the renewable electricity compared to operating a battery-powered electric vehicle.

At present, 96% of hydrogen used for these fuels within the EU is derived from natural gas, a process that releases significant amounts of CO₂. Currently, renewable hydrogen is more costly than fossil-based hydrogen.

“Obtaining pure and concentrated CO₂ poses a considerable challenge,” states Gonzalo Amarante Guimarantes Pereira, a professor at the State University of Campinas in São Paulo, Brazil, and co-author of a study comparing biofuels with pure electric vehicles.

“There is a technology known as direct air capture that can achieve this, but attaining 100% concentration comes with substantial energy costs. The estimated expense varies between $500 to $1,200 (approximately £375 to £895) per tonne, rendering e-fuels at least four to eight times more costly than operating an electric vehicle.”

Browning concurs that EVs represent a more favorable low-carbon choice for the future. “Their emissions during use and maintenance are significantly lower,” he states.

“While synthetic fuels might yield a lesser overall impact if managed wisely, we still lack a comprehensive lifecycle assessment across multiple sustainability metrics to definitively address this issue.”

In simpler terms, as long as the entire system producing synthetic fuels cannot be reliably demonstrated to have a positive environmental impact, the jury remains out on the actual extent of their effects.

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Source: www.sciencefocus.com

Google Celebrates Breakthrough: Quantum Computer Exceeds Supercomputer Performance

Google has announced a significant breakthrough in quantum computing, having developed an algorithm capable of performing tasks that traditional computers cannot achieve.

This algorithm, which serves as a set of instructions for guiding the operations of a quantum computer, has the ability to determine molecular structures, laying groundwork for potential breakthroughs in areas like medicine and materials science.

However, Google recognizes that the practical application of quantum computers is still several years away.

“This marks the first occasion in history when a quantum computer has successfully performed a verifiable algorithm that surpasses the power of a supercomputer,” Google stated in a blog post. “This repeatable, beyond-classical computation establishes the foundation for scalable verification and moves quantum computers closer to practical utilization.”

Michel Devore, Google’s chief scientist for quantum AI, who recently received the Nobel Prize in Physics, remarked that this announcement represents yet another milestone in quantum developments. “This is a further advancement towards full-scale quantum computing,” he noted.

The algorithmic advancement, allowing quantum computers to function 13,000 times faster than classical counterparts, is documented in a peer-reviewed article published in the journal Nature.

One expert cautioned that while Google’s accomplishments are impressive, they revolve around a specific scientific challenge and may not translate to significant real-world benefits. Results for two molecules were validated using nuclear magnetic resonance (NMR), akin to MRI technology, yielding insights not typically provided by NMR.

Winfried Hensinger, a professor of quantum technology at the University of Sussex, mentioned that Google has achieved “quantum superiority”, indicating that researchers have utilized quantum computers for tasks unattainable by classical systems.

Nevertheless, fully fault-tolerant quantum computers—which could undertake some of the most exciting tasks in science—are still far from realization, as they would necessitate machines capable of hosting hundreds of thousands of qubits (the basic unit of information in quantum computing).

“It’s crucial to recognize that the task achieved by Google isn’t as groundbreaking as some world-changing applications anticipated from quantum computing,” Hensinger added. “However, it represents another compelling piece of evidence that quantum computers are steadily gaining power.”

A truly capable quantum computer able to address a variety of challenges would require millions of qubits, but current quantum hardware struggles to manage the inherent instability of qubits.

“Many of the most intriguing quantum computers being discussed necessitate millions or even billions of qubits,” Hensinger explained. “Achieving this is even more challenging with the type of hardware utilized by the authors of the Google paper, which demands cooling to extremely low temperatures.”

Hartmut Neven, Google’s vice president of engineering, stated that quantum computers may be five years away from practical application, despite advances in an algorithm referred to as Quantum Echo.

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“We remain hopeful that within five years, Quantum Echo will enable real-world applications that are solely feasible with quantum computers,” he said.

As a leading AI company, Google also asserts that quantum computers can generate unique data capable of enhancing AI models, thereby increasing their effectiveness.

Traditional computers represent information in bits (denoted by 0 or 1) and send them as electrical signals. Text messages, emails, and even Netflix movies streamed on smartphones consist of these bits.

Contrarily, information in a quantum computer is represented by qubits. Found within compact chips, these qubits are particles like electrons or photons that can exist in multiple states simultaneously—a concept known as superposition in quantum physics.

This characteristic enables qubits to concurrently encode various combinations of 1s and 0s, allowing computation of vast numbers of different outcomes, an impossibility for classical computers. Nonetheless, maintaining this state requires a strictly controlled environment, free from electromagnetic interference, as disturbances can easily disrupt qubits.

Progress by companies like Google has led to calls for governments and industries to implement quantum-proof cryptography, as cybersecurity experts caution that these advancements have the potential to undermine sophisticated encryption.

Source: www.theguardian.com

Data Reveals That the First Half of 2025 Marked the Most Fatal Weather Disaster Ever Recorded.

The initial months of this year marked the highest incidence of weather and climate disasters on record in the United States, as revealed by a recent analysis from the nonprofit Climate Central.

This crucial information may have remained unknown to the general public. Earlier this spring, the Trump administration shut down the National Oceanic and Atmospheric Administration’s program that monitored weather patterns. This event resulted in damages exceeding $1 billion. Adam Smith, the researcher who spearheaded the analysis, left NOAA in response to this decision.

Following his departure, Climate Central, a research organization dedicated to studying climate change impacts, employed Smith to revamp a database with records dating back to 1980.

Their latest analysis indicates that 14 individual weather events caused damages exceeding $1 billion in the first half of 2025. The wildfires in Los Angeles during January represented the most expensive natural disaster thus far this year, incurring costs over $61 billion, making it the most destructive wildfire recorded.

These findings illustrate that the financial toll from weather and climate disasters continues to escalate as extreme weather events become more frequent and severe, while populations migrate to areas increasingly vulnerable to wildfires and floods.

The report serves as a testament to the shift towards nonprofit organizations taking over federal initiatives that traditionally monitored and measured the effects of climate change, particularly as the Trump administration moves to scale back climate science funding. President Trump labeled climate change as a “crook’s job,” and the administration has reduced funding for clean energy initiatives while stripping the Environmental Protection Agency of its ability to control greenhouse gas emissions, which contribute to global warming.

Jennifer Brady, a senior data analyst and research manager at Climate Central involved in the project, noted that the staff was profoundly affected by the discontinuation of NOAA’s extensive disaster database, prompting them to take action.

“This has always been one of our most valued datasets. It narrates diverse stories. It articulates the narrative of climate change as well as the implications of where individuals reside and how they live at risk,” Brady stated. “I am ready to take it home.”

Kim Doster, a spokesperson for NOAA, expressed appreciation that the $1 billion disaster product has secured funding from sources other than taxpayers.

“NOAA remains committed to upholding ethical, unbiased research and reallocating resources to products that comply with executive directives aimed at restoring high standards in science,” Doster conveyed via email.

This database has been a source of political contention. House Republicans raised concerns with NOAA officials in 2024 regarding allegations of “deceptive data.” Recently, Senate Democrats proposed legislation to obligate NOAA to publish and update this dataset biannually, claiming it helps lawmakers in disaster funding decisions. However, this bill is currently stalled in committee and faces bleak prospects in the Republican-majority Senate.

Last month, officials from the Trump administration informed NBC News that NOAA terminated the database project due to uncertainty in accurately estimating disaster costs. The official highlighted that the project would incur annual costs of around $300,000, require considerable staff effort, and yield “pure information at best, with no clear objective.”

“This data is frequently utilized to bolster the claim that climate change enhances the frequency, severity, and expense of disasters, neglecting other factors like increased development in flood-prone and weather-sensitive areas as well as the cyclical variations in climate across different regions,” the official remarked at the time.

Despite this, Brady contends that the database has always acknowledged the significance of population shifts and climate change in exacerbating disaster costs.

She noted that Climate Central’s study employs the same methodologies and data sources as the NOAA database, including claims from the National Flood Insurance Program, NOAA storm event data, private insurance claims, and more.

This analysis captures the “direct costs” of disasters, such as damage to infrastructure, buildings, and crops, while omitting other considerations like loss of life, health-related disaster expenses, and economic losses to “natural capital” such as forests and wetlands. All data has been adjusted for inflation.

A recent evaluation of the first half of 2025 suggests that this year is on track to become the deadliest recorded year, despite the absence of hurricanes making landfall in the continental United States.

In the previous year, NOAA reported that $27 billion in disaster costs totaled around $182.7 billion, marking the second-highest total of billion-dollar disasters in the report’s history, following the figures from 2023.

Climate Central is not alone in its efforts to reproduce the work previously undertaken by the federal government as the Trump administration cut back on climate science.

A collective of dismissed NOAA employees established climate.us, a nonprofit successor to climate.gov, the former federal site that offered data and analyses to help the general public grasp climate issues. The site went offline this summer.

Edited by Rebecca Lindsay climate.gov. Before her termination in February, along with other NOAA colleagues who co-founded the nonprofit, Lindsay stated they had raised about $160,000 with plans to host climate.gov, where they will share their archives and begin publishing new articles on climate change in the upcoming weeks.

“We are preserving this information to ensure that when people seek answers about climate status, they can find them,” Lindsey asserted.

Both the American Geophysical Union and the American Meteorological Society have announced intentions to publish a special collection of studies focused on climate change, particularly after the Trump administration informed volunteer scientists working on the National Climate Assessment that their services were no longer required.

The administration dismissed employees from the U.S. Global Change Research Program, responsible for organizing the National Climate Assessment and coordinating climate research initiatives across various federal offices.

Walter Robinson, from the American Weather Society’s publication committee, highlighted that the National Climate Assessment was “effectively stopped” due to the government’s decision, which he described as an “abandonment” of federal duty.

Though the new collection cannot replace comprehensive assessments, it aims to consolidate the latest scientific understanding on climate change impacts within the United States, he added. The research will be featured in numerous scientific journals on an ongoing basis.

“Individuals are stepping up,” Robinson remarked regarding his group’s endeavors. “As scientists, we do our utmost.”

Source: www.nbcnews.com

Nurturing Your Infant’s Microbiome: A Foundation for Lifelong Mental Health

Families that garden together have more diverse microbiomes

Half Point Images/Getty Images

New parents often juggle numerous worries like sleep schedules, breastfeeding, and even the color of their newborn’s poop, but the baby’s microbiome might not top their list of concerns. Experts suggest it shouldn’t be a priority just yet.

“The initial 1,000 days of life are vital for establishing the microbiome. Once established, altering it is quite challenging,” says Federica Amati from Imperial College School of Medicine. Early microbial colonization plays a significant role not just in physical health, but also in brain development, mental well-being in adolescence, and even in reducing the risk of dementia in later life.

During a meeting I attended, this point seemed crucial for new parents. Goodwood Health Summit held this month in Chichester, England. However, after speaking with nutritionists, microbiologists, and doctors, I became convinced that the importance of introducing microbes early in a child’s life is paramount. There are straightforward, cost-effective strategies to navigate your child’s microbiome in a beneficial direction.

Why early microbiome health is essential

We’re frequently reminded that the trillions of microorganisms comprising our microbiome influence our bodies in various ways, from safeguarding our gut lining to controlling inflammation. But they also impact the brain.

Microbial byproducts influence the formation and adjustment of brain connections during early childhood, a pivotal process for healthy brain growth. Bacteria also communicate with the brain through the vagus nerve, affecting mood and stress levels. Persistent inflammation due to an unbalanced gut microbiome may contribute to depression and neurodegenerative diseases.

Moreover, research has linked microbial imbalance to conditions such as Parkinson’s disease and autism. Early studies suggest that children with autism may present unique microbiome profiles, and fecal transplants from non-autistic donors may offer improvements in both gastrointestinal and behavioral issues.

Ways to nurture the ideal microbiome

Once a microbial ecosystem is set up, overhauling it can be quite difficult, making initial seeding vital. “It’s akin to changing an English garden into a rainforest,” comments Amati, who also serves as the head nutritionist for the Zoe health app.

So how can we foster the ideal growing environment? The gut microbiome begins to flourish even before birth. Bacteria and fungi present in the uterus are consumed by the fetus, and additional microorganisms are transferred during passage through the vaginal canal at birth.

Babies delivered by C-section generally have different gut bacteria, linked to a heightened risk of asthma and eczema, though these discrepancies typically diminish by 6 to 9 months of age.

The advantages of breastfeeding are even more pronounced, as breast milk contains sugars that promote the growth of beneficial bacteria like Bifidobacterium, which is absent in formula. If we liken the microbiome to a garden, these bacteria act as a protective barrier against harmful microbes.

Antibiotics can severely disrupt early microbiome seeding, eliminating both beneficial and harmful bacteria. While antibiotics are often essential, it is crucial for healthcare providers to prescribe them judiciously to safeguard the developing gut, states James Kinross, a colorectal surgeon at Imperial College London.

Post the first year, dietary choices have the most significant impact. Amati emphasizes that variety is crucial, stemming from whole foods rather than ultra-processed snacks commonly provided to young children.

As many parents are aware, young children are notoriously picky eaters. “Prenatal meals are simply a luxury,” explains pediatrician Nancy Bostock, who highlighted that young children don’t need extensive amounts of food. Persistence is key afterward; “Make 20 offers,” she advises. I implemented this approach and despite initial refusal, I continued to serve salmon every Monday for half a year, and my children now love it.

Introducing whole foods doesn’t have to break the bank either. “Canned lentils and frozen raspberries are excellent choices,” adds Amati.

The benefits of getting dirty

Is there a simple and overlooked way to enhance early microbial diversity? Embrace dirt! Research indicates that soil, plant, and human microbiomes are more interconnected than previously understood.

Kinross states that healthy, undisturbed soil is teeming with microorganisms that support the growth of nutrient-dense food for our microbiome. “Our health is inherently linked to the well-being of our soil. The soil microbiome shapes our food, which subsequently influences our health,” he notes.

Additionally, it appears that interacting with soil might directly introduce beneficial microorganisms into the gut, potentially enhancing immune function. Research on the Amish community, for instance, reveals that those who practice traditional farming methods exhibited stronger immune systems compared to Hutterite groups that utilize industrial agriculture. In animal studies, inhaling dust from Amish households (but not from Hutterite homes) showed protective effects against asthma through enhanced microbial immune signaling.

Families who garden together also show seasonal variations in intestinal soil bacteria, implying that microorganisms are introduced via home-grown produce or direct soil contact. Although the long-term influence on children’s microbiomes is still unclear, various studies indicate that families engaging in gardening tend to have greater microbial diversity and higher nutritional quality than those who do not.

You don’t even need a garden to reap these benefits. Spending time outdoors, tending to potted plants, and consuming home-grown produce are all advantageous for your microbiome, according to Amati.

It’s essential not to conflate getting dirty with the outdated “hygiene hypothesis,” which erroneously attributes inflammatory diseases to maintaining a clean home. What we truly require is exposure to beneficial microorganisms, rather than childhood illnesses that can be minimized by proper hygiene.

The old friend hypothesis suggests that humans evolved alongside beneficial microbes from soil, animals, and each other. Changes in our behavior have diminished contact with these beneficial organisms, potentially contributing to the rise of chronic diseases by reducing outdoor activity.

Promoting healthy dietary habits for your child’s mental well-being

Even after the crucial first 1,000 days, the microbiome remains malleable. That’s why fostering a passion for healthy foods in children is crucial, asserts Amati.

Bostock, who specializes in pediatric mental health including eating disorders, warns against limiting specific foods. “Repeatedly, I observe parents struggling to get their kids to eat certain things unless they consume this or that,” she notes. Emphasizing “good” versus “bad” foods can promote eating disorders and obesity, she asserts.

Instead, she advocates for continuous exposure to a range of foods, shared family meals, and celebrating the unique benefits of each food item (whether it be quick energy or bone-strengthening properties).

Lastly, Amati encourages educating children about their microbiome, stating, “Help them understand the role of these beneficial bugs. They find it fascinating and enjoy nourishing the good bacteria.”

topic:

Source: www.newscientist.com

Salesforce CEO Clarifies Remarks on President Trump’s Suggestion to Deploy Troops to San Francisco

Greetings! Welcome to TechScape. I’m your host and editor, Blake Montgomery. Here’s what we’re focusing on this week: South Park’s caricatures of Peter Thiel and his fascination with the Antichrist. Check out our report on Thiel’s odd off-the-record lecture that inspired the show. Now, let’s get started.

Marc Benioff Catches President Trump’s Attention

Last week, the co-founder and CEO of Salesforce suggested that Donald Trump should go ahead with his threat to deploy the National Guard to San Francisco, even amidst local opposition. Even Benioff’s public relations manager was reportedly shocked by his remarks, as per a New York Times article.

Benioff is a well-regarded figure in San Francisco, being the city’s largest private employer. His comments coincided with Salesforce’s flagship conference, Dreamforce, which was set to take over the streets of the city. With a net worth of around $9 billion, according to Forbes, he plays a significant role in the political landscape, particularly within Democratic circles, though his wealth is dwarfed by that of Mark Zuckerberg and Elon Musk.

His statements contradicted his liberal persona and previous declarations, as well as Salesforce’s operational philosophy. The remarks have divided opinions among tech leaders; in fact, one of Salesforce’s board members resigned in protest, while Musk reportedly supported him. My colleague, Dani Anguiano, noted, “Trump megadonor David Sachs, appointed by the president as AI and cryptocurrency czar, remarked that San Francisco could be swiftly eliminated with a ‘targeted operation,’ while Benioff suggested the military could aid police efforts.”

Mr. Benioff issued an apology on Friday, stating, “I have heard the voices of my fellow San Franciscans and local officials…I do not think the National Guard is needed to address security in San Francisco.” He mentioned that security concerns for Dreamforce fueled his comments.

It seems Mr. Benioff managed to provoke discussion without burning too much political capital, having shown a degree of empathy toward the Trump administration. On Monday, President Trump seemed to affirm his “unquestionable authority” to deploy federal troops to San Francisco.

“We’re going to San Francisco. The difference is, they want us in San Francisco,” Trump remarked in an interview.

Read more: President Trump vows to send troops to San Francisco, asserting ‘unquestionable authority’

Amazon Web Services Outage Highlights the Dangers of Centralization

Photo: Anushree Fadnavis/Reuters

My colleagues Dan Milmo and Graeme Wearden report on a significant outage that occurred yesterday in Amazon Web Services, Amazon’s cloud division:

A technical glitch in Amazon’s cloud service resulted in the disruption of applications and websites globally on Monday.

Platforms impacted included Snapchat, Roblox, Signal, Duolingo, and several Amazon-owned businesses, among others.

According to internet outage monitoring site Downdetector, over 1,000 companies were affected around the world, with users reporting 6.5 million issues, including more than 1 million in the U.S., 400,000 in the U.K., and 200,000 in Australia.

Experts have raised concerns regarding the risks of depending on a small cohort of companies to manage the global internet. This failure underscored the inherent dangers of the internet’s reliance on a limited number of tech firms, with Amazon, Microsoft, and Google being pivotal players in the cloud sector.

Dr. Colin Cass Speth, the head of digital at the human rights organization Article 19, remarked, “We urgently need to diversify cloud computing. The infrastructure that supports democratic discourse, independent journalism, and secure communications cannot rely solely on a handful of companies.”

OpenAI’s Sora Creates Dolls of Historical Figures

Photo: Argi February Sugita/ZUMA Press Wire/Shutterstock

OpenAI’s Sora, an AI-driven video generation app, has been thriving since its release, primarily due to its capability to create videos featuring your or your friends’ faces. For instance, I made a jogging-themed version of Ratatouille starring a friend preparing for the New York City Marathon.

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Sora also enables users to create videos featuring the faces of late celebrities. A significant and controversial case was Martin Luther King Jr., whose likeness appeared in many AI-generated videos since Sora’s launch, until the company decided to cease using it following complaints from his estate.

As Niamh Rowe noted, “Videos circulating in my feed show Dr. King making monkey noises during his ‘I Have a Dream’ speech. Other clips depict Bryant reenacting the helicopter crash that tragically claimed his life and that of his daughter.”

Other celebrity estates have echoed similar grievances. Malcolm X’s daughter stated that a video involving her father was “extremely disrespectful and hurtful.” Moreover, the daughter of comedian George Carlin described his AI-generated clip as “overwhelming and depressing” in a Blue Sky post, while Robin Williams’ daughter shared on Instagram that the AI-generated video of her father was “not what he wanted.”

Zelda Williams articulated, “Witnessing real people’s legacies reduced to this… is both horrifying and infuriating, especially with TikTok’s careless puppeteering.”

This trend has repeatedly surfaced with OpenAI. The company tends to be less cautious about reputational risks compared to rivals like Meta, which rolled out an AI-powered video app lacking the ability to deepfake friends concurrently with Sora. Google also withheld its version of ChatGPT for similar reasons; meanwhile, OpenAI’s audacity has allowed it to eclipse Google in this race. They even had to temporarily shut down their image-generating app when it was used to create diverse representations of Vikings. It’s alarming to consider the implications had they let MLK Jr.’s likeness run rampant.

Read more: ‘A legacy of AI missteps’: Video of OpenAI Sora’s death alarms legal experts

Wider TechScape

Source: www.theguardian.com

Major Revelation: Amazon Web Services Outage Highlights UK Government’s £1.7 Billion Reliance on Tech Giant

Amazon’s CEO Andy Jassy wore a broad smile while meeting Keir Starmer in the gardens of Downing Street to announce a £40bn investment in the UK this past June. Starmer shared his enthusiasm, stating, “equally passionate”. He remarked, “This transaction demonstrates that our transformation strategy to attract investment, stimulate growth, and enhance people’s financial well-being is succeeding.”

However, just four months later, the company faced a massive global outage on Monday that halted thousands of businesses and underscored its reliance on Amazon Web Services (AWS), the cloud computing platform utilized by the British government.

Data gathered for the Guardian indicates that the UK government is increasingly dependent on the services of U.S. tech giants. These companies have come under fire from trade unions and politicians for their working conditions in logistics and online retail.

Since 2016, AWS has secured 189 contracts with the UK government valued at £1.7bn and has billed approximately £1.4bn during this timeframe, according to data from public procurement intelligence firm Tassel.

The research group reported: “Currently, 35 public sector authorities utilize AWS services across 41 contracts totaling £1.1bn. The primary ministries involved include the Home Office, DWP, HMRC, the Ministry of Justice, Cabinet Office, and Defra.

Screenshot of the out-of-service HMRC website on Monday, October 20th. Photo: HMRC.gov.uk/PA

Tim Wright, a technology partner at law firm Floodgate, noted that the Financial Conduct Authority (FCA) and Prudential Regulation Authority (PRA) have consistently warned about the risks associated with concentrating cloud services for regulated enterprises.

“Recent efforts by the Treasury, the PRA, and the FCA to impose direct oversight on ‘significant third parties’ aim to mitigate the risk of outages like those faced by AWS,” he said. “However, until we see substantial diversification and the establishment of sovereign clouds, the UK government’s approach contradicts the resilience principles that regulators advocate for.”

The House of Commons Treasury Committee has reached out to Chancellor of the Exchequer Lucy Rigby to inquire why Amazon wasn’t classified as a “significant third party” within the UK financial services sector, a designation that would have subjected the tech giant to regulatory scrutiny.

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Committee Chair Meg Hillier noted that Amazon recently informed the committee that its financial services clients rely on AWS for “resilience” and that AWS offers “layers of protection.”

This week’s outage impacted over 2,000 businesses around the globe, leading to 8.1 million reports of issues, with 1.9 million in the U.S., 1 million in the UK, and 418,000 in Australia, according to internet outage tracker Downdetector.

Only HMRC confirmed it was affected by the outage, stating customers were “experiencing difficulties accessing our online services” and recommended they call back later due to busy phone lines.

While many websites restored their services after a few hours, some continued to experience problems throughout the day. By Monday evening, Amazon announced that all cloud services had “returned to normal operations.”

Trade unions have long questioned whether Amazon should be excluded from government contracts because of its reputation for subpar working conditions in its large warehouses.

Andy Prendergast, national secretary of the GMB union, stated: “Amazon has a dismal record regarding fair treatment of workers. Shocking conditions in their warehouses have resulted in emergency ambulance calls, with employees claiming they are treated like robots, forced to work until exhaustion, all while being compensated with poverty wages until they strike for six months.”

“In this context, wasting nearly £2 billion of public funds is deplorable.”

AWS has not provided a comment. A spokesperson from Amazon’s fulfillment centers stated that the “vast majority” of ambulance calls at their facilities are not “work-related.”

Source: www.theguardian.com

ChatGPT Atlas: OpenAI Introduces Chatbot-Focused Web Browser | Tech News

On Tuesday, OpenAI unveiled an AI-driven web browser centered around its renowned chatbot.

“Introducing the revolutionary browser ChatGPT Atlas” Tweet from the company stated.

This browser aims to enhance the web experience with a ChatGPT sidebar, enabling users to ask questions and engage with various features of each site they explore, as demonstrated in a video shared with the announcement. Atlas is currently accessible worldwide on Apple’s macOS and will soon be released for Windows, iOS, and Android, according to OpenAI’s announcement.

With the ChatGPT sidebar, users can request “content summaries, product comparisons, or data analysis from any website.” Website for more details. The company has also begun presenting a preview of its virtual assistant, dubbed “Agent Mode,” to select premium users. Agent Mode allows users to instruct ChatGPT to execute a task “from start to finish,” such as “travel research and shopping.”

While browsing, users can also edit and modify highlighted text within ChatGPT. An example on the site features an email with highlighted text along with a recommendation prompt: “Please make this sound more professional.”

OpenAI emphasizes that users maintain complete control over their privacy settings: “You decide what is remembered about you, how your data is utilized, and the privacy settings that govern your browsing.” Currently, Atlas users are automatically opted out of having their browsing data employed to train ChatGPT models. Additionally, similar to other browsers, users can erase their browsing history. However, while the Atlas browser may not store an exact duplicate of searched content, ChatGPT will “retain facts and insights from your browsing” if users opt into “browser memory.” It remains unclear how the company will handle browsing information with third parties.

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OpenAI is not the first to introduce an AI-enhanced web browser. Companies like Google have incorporated their Gemini AI models into Chrome, while others such as Perplexity AI are also launching AI-driven browsers. Following the OpenAI announcement, Google’s stock fell 4%, reflecting investor concerns regarding potential threats to its flagship browser, Chrome, the most widely used browser globally.

Source: www.theguardian.com

Prince Harry and Duchess Meghan Advocate for a Ban on Superintelligent AI Systems Alongside Technology Pioneers

The Duke and Duchess of Sussex have joined forces with AI innovators and Nobel laureates to advocate for a moratorium on the advancement of superintelligent AI systems.

Prince Harry and Duchess Meghan are signatories of a declaration urging a halt to the pursuit of superintelligence. Artificial superintelligence (ASI) refers to as-yet unrealized AI systems that would surpass human intelligence across any cognitive task.

The declaration requests that the ban remain until there is a “broad scientific consensus” and “strong public support” for the safe and controlled development of ASI.

Notable signatories include AI pioneer and Nobel laureate Jeffrey Hinton, along with fellow “godfather” of modern AI, Yoshua Bengio, Apple co-founder Steve Wozniak, British entrepreneur Richard Branson, Susan Rice, former National Security Advisor under Barack Obama, former Irish president Mary Robinson, and British author Stephen Fry. Other Nobel winners, like Beatrice Finn, Frank Wilczek, John C. Mather, and Daron Acemoglu, also added their names.

The statement targets governments, tech firms, and legislators, and was sponsored by the Future of Life Institute (FLI), a US-based group focused on AI safety. It called for a moratorium on the development of powerful AI systems in 2023, coinciding with the global attention that ChatGPT brought to the matter.

In July, Mark Zuckerberg, CEO of Meta (parent company of Facebook and a key player in U.S. AI development), remarked that the advent of superintelligence is “on the horizon.” Nonetheless, some experts argue that the conversation around ASI is more about competition among tech companies, which are investing hundreds of billions into AI this year, rather than signaling a near-term technological breakthrough.

Still, FLI warns that achieving ASI “within the next 10 years” could bring significant threats, such as widespread job loss, erosion of civil liberties, national security vulnerabilities, and even existential risks to humanity. There is growing concern that AI systems may bypass human controls and safety measures, leading to actions that contradict human interests.

A national survey conducted by FLI revealed that nearly 75% of Americans support stringent regulations on advanced AI. Moreover, 60% believe that superhuman AI should not be developed until it can be demonstrated as safe or controllable. The survey of 2,000 U.S. adults also found that only 5% endorse the current trajectory of rapid, unregulated development.

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Leading AI firms in the U.S., including ChatGPT creator OpenAI and Google, have set the pursuit of artificial general intelligence (AGI)—a hypothetical state where AI reaches human-level intelligence across various cognitive tasks—as a primary objective. Although this ambition is not as advanced as ASI, many experts caution that ASI could unintentionally threaten the modern job market, especially due to its capacity for self-improvement toward superintelligence.

Source: www.theguardian.com

iPhone 17 Review: The Must-Have Apple Smartphones of the Year

While it may not seem as distinct as this year’s refreshed Pro models, or as sleek as the new iPhone Air, the iPhone 17 signifies a significant milestone for standard Apple smartphones.


This is especially noteworthy since Apple has finally introduced a high-refresh-rate 120Hz display, a top feature of modern smartphones, into its base model flagship.

Moreover, the starting storage has been doubled without a price increase. The iPhone 17 is priced the same as its predecessor at £799 (€949/$799/AU$1,399), which is less than the £999 Air and £1,099 Pro, yet it offers substantial value for the price.

Externally, it appears similar to the iPhone 16, but the 17 is slightly taller, allowing for a bigger screen fitting into slimmer bezels without greatly increasing the phone’s overall dimensions. The 6.3-inch display now rivals the ultra-bright screen of the 17 Pro, protected by enhanced toughened glass for better scratch resistance.




The new anti-glare coating on the screen enhances visibility and usability, even in bright sunlight. Photo: Samuel Gibbs/The Guardian

The 120Hz “promotion” technology significantly increases the screen refresh rate, resulting in smoother scrolling and animations. This feature has been a staple in competitor smartphones for years, while Apple reserved it for Pro versions of its devices until now.

Additionally, the 17 now includes features previously exclusive to Pro models, such as the Always-On Display, which shows widgets and notifications while the phone is idle. It operates on the same iOS 26 as the entire iPhone range and offers Apple’s revamped glass-like interface design, which appears somewhat simplified to reduce on-screen distractions while maintaining functionality.

Specifications

  • Screen: 6.3 inch Super Retina XDR (120Hz OLED) (460ppi)

  • Processor: Apple A19

  • RAM: 8GB

  • Storage: 256 or 512GB

  • Operating System: iOS 26

  • Camera: 48MP Main + 48MP UW; 18MP Front

  • Connectivity: 5G, Wi-Fi 7, NFC, Bluetooth 6, Thread, USB-C, Satellite, UWB, GNSS

  • Water Resistance: IP68 (30 minutes at 6 meters)

  • Size: 149.6×71.5×7.95mm

  • Weight: 177g

Fast A19 Chip and Solid Battery Life




Using a 20W or higher USB-C power adapter (sold separately), your phone can fully charge in 82 minutes, reaching 50% in just 21 minutes. Photo: Samuel Gibbs/The Guardian

Powered by Apple’s new A19 chip, the iPhone 17 is among the fastest in the smartphone market, being only slightly less powerful than the A19 Pro. Apple maintains a technological edge over Android rivals, even in its more budget-friendly offerings.

As a result, the 17 manages multitasking and various applications with ease. Its battery performance is commendable for its size, lasting around 44 hours between charges using Wi-Fi and 5G, and about 6 hours of active screen use with the always-on feature. Though slightly reduced from its predecessor, it offers longer life than the comparably sized 17 Pro and notably outlasts the iPhone Air. Most users will require charging the 17 every other day.

Sustainability




The sleek recycled aluminum body and matte glass back provide a solid and premium feel, even without a protective case. Photo: Samuel Gibbs/The Guardian

The battery lasts over 1,000 full charge cycles while maintaining at least 80% of its original capacity; replacement costs £95. Note that screen repair is £349 and is not covered by warranty.

This device consists of over 30% recycled materials encompassing aluminum, cobalt, copper, gold, lithium, plastic, rare earth elements, steel, tin, and tungsten. Apple evaluates its environmental impact through various reports and offers trade-in and free recycling programs, even for non-Apple devices.

Camera




The camera app has been streamlined by concealing many features behind a sliding selector and pop-out menus to maximize the viewfinder space. Photo: Samuel Gibbs/The Guardian

The iPhone 17 features two 48-megapixel rear cameras (main and ultrawide), alongside Apple’s new 18MP front-facing camera found on the iPhone 17 Pro and Air.

While the main camera remains unchanged from the iPhone 16, it captures excellent photographs in various lighting scenarios. It may occasionally overexpose in bright light or appear slightly blurry in low-light conditions, yet it remains a dependable compact digital option. It supports a 2x crop zoom, effective in bright areas and acceptable in dim indoor settings. The ultrawide camera is notably enhanced from the previous model, enabling more detail and a broader range, particularly effective for macro photography.

Despite the camera’s ability to achieve a digital zoom of up to 10x, resulting images may lack detail and clarity. True telephoto capabilities remain exclusive to Pro models.

The front camera delivers slightly improved selfies compared to previous iterations, with a standout feature allowing it to digitally pan and zoom to encompass all subjects in a group shot, regardless of phone orientation—ideal for capturing landscape shots while holding the phone vertically.

The iPhone 17 offers various shooting modes for video capture, including a dual capture mode that records from both front and rear cameras simultaneously, placing the user in a small inset frame.

Price

Pricing for the iPhone 17 starts at £799 (€949/$799/AU$1,399) for the 256GB version.

By comparison, the iPhone 16e retails for £599, the iPhone Air is priced at £999, the iPhone 17 Pro costs £1,099, the iPhone 17 Pro Max is £1,199, and the Google Pixel 10 is also £1,199. The Samsung Galaxy S25 is priced at £699, while the Fairphone 6 retails at £499.

Verdict

While the iPhone 17 may not visually distinguish itself from its predecessor, it represents a notable advancement over previous standard iPhones.

The incorporation of key features from Apple’s more premium Pro models—including a superior, brighter, and smoother 120Hz display—is particularly significant. An always-on display enhances functionality, and the doubling of base storage to 256 GB, along with improved battery life extending roughly two days, are both highly appreciated changes. After years, the iPhone 17 no longer feels like a substantial downgrade from the Pro model.

The dual rear cameras are impressive, though the absence of a telephoto option limits their capabilities somewhat. The iPhone 17 retains a compact feel for a modern smartphone, akin to the iPhone Air but without being onerously heavy.

For users not requiring a telephoto lens, the standard iPhone 17 is an excellent choice.

Pros: Rapid performance, impressive 120Hz display, quality dual cameras with macro functionality, minimum of 256GB storage, comfortable size, tactile action and camera control buttons, USB-C, robust battery life, extended software support, Face ID.

Cons: No telephoto lens, identical design to its predecessor, not the thinnest, lightest, or most powerful option.




The iPhone 17 remains the last model with a straightforward two-camera configuration, arranged vertically on the back, making it less obtrusive compared to other models. Photo: Samuel Gibbs/The Guardian

Source: www.theguardian.com

Astronomers Capture Direct Images of Brown Dwarfs Orbiting Nearby Red Dwarfs

Astronomers utilized the Subaru Telescope, W.M. Keck Observatory, and ESA’s Gaia mission to capture images of the brown dwarf companion orbiting the M dwarf star LSPM J1446+4633.



NIRC2 image of J1446 taken in August 2023. The white arrow indicates the location of the new companion J1446B. Image provided by: Uyama et al., doi: 10.3847/1538-3881/ae08b6.

LSPM J1446+4633 (J1446) is a nearby mid-M dwarf, situated 17 parsecs (55 light-years) away.

The newly identified brown dwarf orbits its parent star at a distance approximately 4.3 times that of the Earth from the sun, completing an orbit every 20 years.

This object, designated J1446B, has a mass ranging from 20 to 60 times that of Jupiter.

“The success of this discovery was due to the combination of three complementary observational methods: (i) radial velocity (RV) measurements via long-term infrared spectroscopic monitoring by Subaru’s IRD instrument, (ii) high-resolution near-infrared imaging with advanced adaptive optics at the W.M. Keck Observatory, and (iii) precise astronomical acceleration measurements from ESA’s Gaia mission,” stated California State University astronomer Taichi Uyama and his team.

“By integrating these datasets and applying Kepler’s laws, we were able to determine the dynamic mass and orbital parameters of J1446B with unprecedented precision.”

“Radial velocity data by itself cannot differentiate between mass and orbital inclination, but the addition of direct imaging and Gaia data resolves this ambiguity.”

“The Subaru IRD-SSP program provided crucial RV data, while Keck’s cutting-edge adaptive optics allowed for the direct detection of the companion star at very close distances from the host star.”

“Previous studies have shown that astronomical acceleration from Hipparcos and Gaia can be combined with direct imaging to detect and analyze companion objects.”

“However, Hipparcos was unable to measure faint red dwarf stars like J1446.”

“Our study is the first to apply Gaia-only acceleration data to such a system, successfully constraining the orbit and dynamical mass of a brown dwarf companion.”

Near-infrared observations of J1446B indicated a brightness variation of about 30%, hinting at dynamic atmospheric phenomena such as clouds or storms.

“This finding serves as a significant benchmark for testing brown dwarf formation theories and atmospheric models,” the astronomers noted.

“Future spectroscopic studies may enable researchers to map the weather patterns on this intriguing object.”

“This achievement highlights the efficacy of combining ground-based and space-based observatories in discovering hidden worlds beyond our solar system.”

The team’s paper was published in Astronomy Magazine.

_____

Taichi Uyama et al. 2025. Direct Image Exploration for Companions with Subaru/IRD Strategic Program II. A brown dwarf companion star was discovered around the nearby medium-M dwarf LSPM J1446+4633. A.J. 170, 272; doi: 10.3847/1538-3881/ae08b6

Source: www.sci.news

Scientists Suggest Total Solar Eclipse May Prompt Dawn Behavior in Birds

On April 8, 2024, a total solar eclipse interrupted the daylight cycles of North American birds as they prepared for spring breeding. Researchers at Indiana University, after analyzing over 10,000 community observations and utilizing artificial intelligence to examine nearly 100,000 bird calls, discovered that bird behavior was significantly impacted by the few minutes of unexpected afternoon darkness. More than half of the bird species altered their biological rhythms, leading many to produce dawn choruses in the aftermath of the eclipse.



Circles indicate individual observations from the SolarBird app submitted on April 8, 2024. Image courtesy of Aguilar et al., doi: 10.1126/science.adx3025.

The daily and seasonal rhythms of birds are closely regulated by variations in light and darkness.

What occurs when these cycles are abruptly disrupted, such as during a total solar eclipse?

Previous research has explored the effects of solar eclipses on animal behavior, yet many studies have only provided scattered or anecdotal insights regarding animal responses.

Indiana University researcher Liz Aguilar and her team viewed the total solar eclipse in April 2024 as a unique research opportunity, offering an unprecedented natural experiment to observe how birds react to sudden light changes.

In preparation for the solar eclipse that would cast nearly four minutes of darkness over large regions of the central and eastern United States, they developed a smartphone app called SolarBird, which allows users to document bird behaviors in real time during the eclipse.

The citizen scientists’ contributions resulted in almost 10,000 observations spanning 5,000 km along the eclipse’s path.

Simultaneously, researchers deployed autonomous recording devices across southern Indiana to capture the calls of about 100,000 birds before, during, and after the totality.

These recordings were analyzed using BirdNet, an AI system capable of identifying species calls and measuring vocal activity.

Findings revealed that 29 out of 52 species detected exhibited significant changes in their singing behavior at various points during the event, although the eclipse’s effects varied among species.

In the moments leading up to the eclipse, 11 species were found to sing more than usual as darkness approached.

During the four minutes of darkness, 12 species reacted—some becoming silent, while others increased their vocal activity.

The most notable responses were observed after the sun re-emerged, with 19 species adjusting their songs to mimic a false dawn chorus.

Notably, barred owls hooted four times more frequently than usual, while robins—renowned for their pre-dawn melodies—hooted six times more than normal.

“These patterns indicate that the solar eclipse temporarily reset the internal clocks of certain birds, causing them to act as if a new day had commenced,” the researchers stated.

Their paper was published in the October 9, 2025 edition of the journal Science.

_____

Liz A. Aguilar et al. 2025. Total solar eclipses trigger dawn behavior in birds: Insights from acoustic recordings and crowd science. Science 390 (6769): 152-155; doi: 10.1126/science.adx3025

Source: www.sci.news

Antidepressants Can Cause a Diverse Range of Physical Side Effects.

Different individuals may respond better to certain antidepressants based on their side effects.

Maria Vekulenko/Getty Images

The side effects of antidepressants can differ significantly, ranging from weight fluctuations to alterations in blood pressure. Medical professionals need to consider these factors when selecting the most appropriate medication among the numerous options available.

About 10% of individuals in Europe and the US utilize antidepressants to address symptoms including depression and anxiety. Withdrawal symptoms may not be as prevalent as assumed, yet some studies indicate physical side effects associated with these medications. The specific side effects linked to each drug, however, remain unclear.

Diving deeper into the research, Toby Pillinger and his team from King’s College London examined data from 151 randomized controlled trials and 17 reports from the US Food and Drug Administration. These studies encompassed 30 different antidepressants, assessing their efficacy and side effects relative to a placebo over roughly eight weeks for various mental health conditions.

“The strength of these studies lies in their placebo-controlled and randomized design, allowing us to confidently attribute the observed differences to the medications,” Pillinger states.

The analysis revealed that certain medications were linked to weight loss, while others caused weight gain. For instance, maprotiline was associated with an average weight gain of approximately 1.8 kg, whereas agomelatine was linked to an average weight loss of about 2.4 kg.

The research additionally indicated that fluvoxamine led to an average decrease in heart rate of 8 beats per minute (bpm), while nortriptyline raised it by 13 bpm. Notably, nortriptyline also lowered systolic blood pressure (the pressure during heart contractions) by 3 to 7 millimeters of mercury (mmHg), whereas doxepin elevated blood pressure by nearly 5 mmHg, which may have wider health implications. “For every 1 mmHg increase in blood pressure, the risk of stroke rises by 1%,” remarks Oliver Howes, also from King’s College London.

Other medications like paroxetine, duloxetine, desvenlafaxine, and venlafaxine have been linked to increased cholesterol levels. It remains uncertain if these side effects intensify, diminish, or stabilize after the initial eight-week period.

Although observational studies have raised concerns regarding the potential impact of antidepressants on electrolyte levels, particularly sodium—as it may influence heart rhythms—”our study indicates that sodium isn’t an issue at all,” Pillinger comments.

In the UK, over 92 million antidepressants were prescribed last year, with approximately 85% being either sertraline, mirtazapine, fluoxetine, amitriptyline, citalopram, or venlafaxine. Among these, four exhibited relatively favorable profiles for various evaluated factors; however, amitriptyline was noted for increasing body weight, heart rate, and blood pressure, while venlafaxine was found to elevate heart rate, blood pressure, and cholesterol levels.

“This information is immensely useful for both physicians and patients,” remarks Mahyar Etminan from Epilytics, an epidemiological consulting firm in Vancouver. “This data can be integrated into an application, enabling doctors to identify which medications to avoid for individuals with high cholesterol or cardiovascular issues. It provides physicians with greater flexibility in selecting the most suitable antidepressant for their patients.”

Pillinger mentions that his team is developing a digital tool that features a drop-down list of common side effects associated with antidepressants, assisting healthcare providers in determining which medications to avoid or whether reducing dosage could be advantageous. “The essential goal is to find the most appropriate drug for each individual and tailor prescriptions accordingly,” Pillinger explains.

However, John Ioannidis, a researcher at Stanford University, cautions that their findings could be skewed if only studies demonstrating side effects were included. Some research may not have reported any adverse effects, thus excluding pertinent data from the meta-analysis.

He also points out that patients typically remain on antidepressants for at least eight weeks, often for several years. “If such an impact exists over a more extended period, it necessitates different long-term studies to validate its relevance,” Ioannidis asserts.

Pillinger acknowledges the possibility of bias but believes they have compiled the majority of relevant data. He recognizes the need for long-term study analysis and is in the process of conducting it, mentioning that around 75% of trial participants have been white. Nonetheless, he believes the trends identified will likely become clearer over extended studies and may extend to other demographics.

Prior research has indicated that some antidepressants, such as venlafaxine, are associated with long-term blood pressure increases. He also notes that rapid weight gain might persist. “Once weight is gained, it becomes challenging to lose it again,” he states.

However, due to the effectiveness of antidepressants, those worried about side effects should not discontinue their medication, according to Howes. “This is a nuanced issue and an individual decision that considers your unique risk factors and benefits. If concerned, consulting with your physician is advisable.”

Topic:

  • Medical drugs /
  • Depression

Source: www.newscientist.com

ALMA Observes Spiral Gas Streamers Controlled by Magnetic Fields in Star-Forming Areas

This stream of gas transports material from the clouds surrounding the star-forming area within Perseus directly into an emerging binary star system known as SVS 13A.

Artist’s impression of the SVS 13A system. Image credit: NSF/AUI/NSF’s NRAO/P.Vosteen.

Stars are formed from clouds of gas and dust, and recent observations indicate that the process of star formation is far more dynamic than previously understood.

New findings from the Atacama Large Millimeter/Submillimeter Array (ALMA) reveal both dust and molecules swirling around the SVS 13A system. This data shows how the magnetic field not only permeates these stellar nurseries but actively directs the flow of matter, offering a preferred path for gas to accumulate in the disk where new stars and planets arise.

“Visualize a garden hose, but instead of water, it smoothly channels materials for star formation through intricate pathways carved by unseen forces,” explains Dr. Paulo Cortes, an astronomer at the NSF National Radio Astronomy Observatory and the joint ALMA telescope.

“This perspective from ALMA observations presents channels of gas known as subalfvénic streamers, regulated by spiral magnetic field lines.”

“This new data provides an insightful glimpse into the star formation process.”

“These streamers illustrate how magnetic fields can influence star formation by managing material influx, akin to a private highway facilitating car travel.”

ALMA’s images and findings uncover two spiral arms of dust encircling the star, with gas streams closely mirroring the same trajectory.

This remarkable configuration implies that the gas within the streamer is traversing at a slower pace than previously believed, reinforcing the concept of a magnetized channel rather than a chaotic, collapsing cloud.

The presence of such streamers, linking clouds to disks and supplying them with material in a managed fashion, indicates that both gravity and magnetism are crucial in the formation of stars and the shaping of potential planetary bodies around them.

This groundbreaking result signifies the first instance where astronomers have directly mapped both a streamer and its associated magnetic field in a single observation.

“Subalfvenic streamers indicate a fresh role for magnetic fields amidst gravitational dominance, acting as ‘guides’ to assist the descent of material from the outer envelope to the disk,” the astronomers remarked.

Upcoming findings are detailed in a paper in the Astrophysics Journal Letter.

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PC Cortez et al. 2025. First results from ALPPS: SVS 13A subalfvenic streamer. APJL 992, L31; doi: 10.3847/2041-8213/ae0c04

Source: www.sci.news

Elon Musk Responds Rashly After NASA Reveals Plans to Source Lunar Lander from SpaceX Competitor

NASA’s Acting Administrator Sean Duffy seems to have drawn the ire of Elon Musk.

Elon Musk, founder and CEO of SpaceX, took to social media on Tuesday to criticize Mr. Duffy’s intelligence and recent actions as the leader of the space agency.

“Sean Dummy is trying to destroy NASA!” Musk stated on X, using a derogatory nickname for the acting administrator. In another post, he remarked: “There’s no way the leader of America’s space program can have a double-digit IQ.”

On Monday, Duffy announced that NASA is considering utilizing a lunar lander from a SpaceX competitor to help return astronauts to the moon before China establishes its presence there.

NASA initially planned to use SpaceX’s next-generation Starship rocket system for the lunar landing.

Musk conducted a poll on Tuesday asking his followers on X: “Should someone whose greatest achievement is climbing trees lead America’s space program?” One option was, “Yes, chimpanzees are good at it!” while the other suggested, “No, he needs More Brains!”

By Tuesday afternoon, the poll had garnered around 110,000 votes.

In 2021, SpaceX secured a $2.9 billion contract to use its Starship rocket to land two astronauts on the moon during NASA’s Artemis III mission, aimed for a 2027 launch.

However, Musk’s company has faced delays in the testing and development of Starship, which experienced several explosions this year.

Meanwhile, political pressure is mounting as the competition with China escalates; the nation is targeting a moon landing by 2030 and has already dispatched two robotic probes and tested a new rocket for manned lunar missions.

Duffy appeared on Fox News and CNBC on Monday, stating that NASA would expand the Artemis III contract, inviting proposals from rival space companies to maintain U.S. competitiveness against China.

“We are not going to wait for a single company,” Duffy reiterated in an appearance on CNBC’s “Squawk Box.” on Monday. “We are focused on moving forward and winning the second space race against China.”

Duffy mentioned his and President Donald Trump’s goal to return astronauts to the moon during Trump’s second term.

He cited Blue Origin, the space launch company founded by Jeff Bezos, as a potential competitor capable of providing unique technology.

This statement appeared to antagonize Musk.

In a subsequent post, Musk questioned the ability of other commercial space firms to meet such stringent deadlines.

“In comparison to other space industries, SpaceX is advancing at remarkable speed,” he asserted. “Moreover, Starship will ultimately execute the full lunar mission. Mark my words.”

In reality, SpaceX is so ahead of its rivals that it is already conducting regular NASA missions to transport astronauts and cargo to the International Space Station.

Reacting to Musk’s remarks, Duffy replied on X: “Love the enthusiasm. The race to the moon is on. Great companies should welcome challenges. Competition among innovators benefits America!”

However, Musk’s tirade on Tuesday took a personal turn, questioning Duffy’s competence to lead NASA. Duffy is temporarily in charge of the agency; a Wall Street Journal report suggested he is positioning himself to continue in that role alongside his responsibilities as transportation secretary.

The report indicated that Duffy is contending against billionaire Jared Isaacman, who may reemerge as a candidate for the NASA leadership position. Trump had retracted Isaacman’s nomination in May, just ahead of an anticipated confirmation vote. This withdrawal followed what the president described as a “thorough review of prior connections.” (Trump did not elaborate, but some Republicans had expressed reservations that Isaacman previously donated to Democrats.)

Musk has shown support for Isaacman, who has made two orbital flights on commercial SpaceX missions.

NASA spokesperson Bethany Stevens informed NBC News that President Trump has asked Duffy to consult with potential administrators, and that the interim administrator “will be glad to assist by evaluating candidates and providing honest feedback.”

“Sean is thankful to the president for this opportunity to lead NASA,” Stevens stated. “At the president’s direction, Sean is committed to ensuring America returns to the moon before China. He has indicated that NASA’s integration into the Cabinet, possibly even the Department of Transportation, might be beneficial, though he has never claimed he wishes to continue in this role.”

The White House did not respond to inquiries for comment.

The timing of Isaacman’s controversy in May coincided with a public feud between Trump and Musk, which escalated before the SpaceX CEO departed the White House on a special public service assignment. Musk’s departure was fraught with tension as he criticized President Trump’s “One Big Beautiful Bill,” labeling it a “huge, outrageous, pig-filled Congressional spending plan” and a “distasteful, ugly bill” that would exacerbate the budget deficit.

playing cards We welcomed Duffy in July. Becomes interim administrator of NASA.

Source: www.nbcnews.com

Exclusive: Climate Scientists Anticipate Solar Dimming Efforts by 2100

Solar geoengineering aims to block some sunlight.

PA Images/Alamy

A study by top climate scientists projects that by the end of this century, humanity will undertake significant measures to block sunlight as a desperate effort to safeguard Earth’s population from the escalating impacts of climate change, as reported by New Scientist.

“Solar geoengineering is a troubling concept, yet it is becoming more appealing as global efforts to reduce greenhouse gas emissions fall short,” stated a respondent from Victoria University of Wellington, James Renwick.

According to the study, two-thirds of participants anticipate hazardous interventions will be employed to manage the atmosphere by the year 2100. Alarmingly, 52% believe these actions could be taken by irresponsible entities, including private firms, wealthy individuals, and nation-states, highlighting fears that attempts to cool the climate may proceed without comprehensive global governance to address decision-making or mitigate inherent risks.

“The potential for unintended consequences, political misuse, and abrupt climate impacts remains substantial,” a respondent remarked. Ines Camilloni of the University of Buenos Aires, Argentina, noted these concerns.


New Scientist invited around 800 climate researchers, contributors to the Intergovernmental Panel on Climate Change’s (IPCC) latest report, to participate in an anonymous online survey concerning solar geoengineering. The 120 respondents represented diverse academic fields from all continents, yielding one of the most extensive insights into the climate science community’s stance on solar geoengineering so far.

Since the 1960s, scientists have been exploring ways to enhance Earth’s albedo—the reflectivity of the planet—for a procedure known as solar geoengineering or solar radiation modification (SRM).

Cooling strategies might include the injection of particles into the upper atmosphere to reflect sunlight away from Earth, known as stratospheric aerosol injection. Another suggestion involves introducing salt particles into low-altitude ocean clouds, referred to as ocean cloud brightening (see “How does solar geoengineering operate?” below).

Solar geoengineering may involve injecting sea salt into ocean clouds.

San Francisco Chronicle/Yalonda M. James/eyevine

68% of respondents indicated that due to the global failure to reduce greenhouse gas emissions over the last decade, the likelihood of deploying such measures has increased. “It reflects a growing realization that we are not addressing climate change effectively,” noted Sean Fitzgerald from the Center for Climate Change Remediation at the University of Cambridge. “What options do we have? We may not prefer them, but if we disapprove of the current situation, we must consider alternatives.”

While consensus exists regarding the potential for solar geoengineering, experts disagree on the triggers for such drastic measures. Just over 20% of respondents believe these measures should be considered should global temperatures be on track to rise more than 2°C above pre-industrial levels, a scenario that is becoming increasingly likely with global warming surpassing the 1.5°C mark. Others argued that waiting for more extreme warming would be wiser, while over half felt current warming levels were insufficient to warrant serious consideration of atmospheric alteration.

Such actions could theoretically help lower global temperatures and provide time for emissions reductions, yet nearly all respondents recognized substantial risks associated with widespread implementation, including diminished motivation to cut emissions, disruption to vital agricultural rainfall patterns, and abrupt warming due to “termination shock” should these interventions cease.

The study further highlighted concerns regarding unilateral climate interventions by nations or individuals, with 81% of respondents agreeing that a new international treaty or framework is necessary to regulate all large-scale deployments, marking a significant consensus across the survey questions.

These findings reflect a cautious stance, according to Andy Parker from the Degrees Initiative. “This is a global technology. No nation can opt out of a geoengineered world. Similarly, no nation can choose to ignore a warmer world if geoengineering is rejected.”

Growing Interest in Geoengineering

New Scientist decided to undertake this research as interest in solar geoengineering grows amid escalating climate impacts. Hundreds of millions of dollars in funding are flowing into this area, with researchers presenting their findings at scientific forums, building a global research community. Earlier this year, the UK Government allocated £57 million in grants for solar geoengineering research via the Advanced Research and Inventions Agency (ARIA), supporting small-scale field experiments.

This represents a significant pivot for a field traditionally sidelined within climate science. Daniele Visioni has led numerous SRM modeling projects at Cornell University in New York. “This topic has transitioned from being loosely discussed by a small group of scholars to becoming a global issue.”

Just over one-third of the respondents from New Scientist‘s survey asserted that due to humanity’s ongoing struggle to cut emissions, they now support SRM research, albeit not necessarily its implementation. A notable 49% are in favor of conducting small-scale outdoor experiments to better understand the associated risks and benefits.

Accelerated cloud cooling could lead to drought in East Africa.

Fadel Senna/AFP via Getty Images

“There is growing acceptance of the necessity of SRM research,” Parker states, tying it directly to the increased pessimism surrounding climate change outcomes.

“Given that most surveyed experts believe solar radiation management is probable within the next century, we must collect comprehensive real-world data regarding the feasibility and potential impacts of these cooling strategies,” asserts Mark Symes, director of ARIA’s Climate Cooling Program.

However, support is by no means unanimous, with approximately 45% of respondents deeming this a contentious or taboo research area. A third opposed outdoor experimentation with any countermeasures, and 11% refrained from contributing to solar geoengineering studies to protect their professional reputation.

“Many of these climate scientists see that the initial vision of climate science—to heed the warnings of the Earth and reduce emissions—has failed,” according to Visioni.

Much hesitance regarding solar geoengineering stems from the multitude of potentially catastrophic risks associated with large-scale sunlight-reflecting efforts.

Almost all respondents noted that implementation might dampen motivation to reduce emissions as one of the most critical risks. Other significant threats included social and political unrest, severe disruptions to agriculture and food security, harm to delicate ecosystems, and public health crises. “Modifying the entire climate system through SRM is a considerable risk,” cautioned Shreekant Gupta at the Center for Social and Economic Progress in Delhi, India.

For instance, research indicates that enhancing cloud cooling effects over the Indian Ocean could mitigate droughts in North Africa while triggering droughts in East Africa. Additional studies suggest that aerosol injections into the stratosphere could damage the ozone layer and potentially reduce monsoon rainfall in parts of Africa by up to 20%.

However, the ambiguity of “unknown consequences” emerged as the most commonly mentioned risk. One survey participant pointed out that “human efforts to rectify damaged systems have often met with limited success.”

Three primary techniques for solar geoengineering include:

1. Stratospheric aerosol injection
This technique involves dispersing tiny liquid particles called aerosols from high-altitude aircraft to reflect sunlight. Over 60% of survey respondents identified this as the method most likely to be adopted.

2. Thinning of cirrus clouds
This method utilizes aerosols such as nitric acid to thin cirrus clouds, permitting more heat to escape into space. However, excessive aerosol spraying can thicken clouds and produce the opposite effect. Only a minority of respondents believed this method or land-based strategies for enhancing global albedo could be pursued.

3. Brightening ocean clouds
This approach involves spraying minute seawater droplets onto clouds, enhancing their brightness and increasing sunlight reflection. It was trialed in a small experiment in 2024 aimed at protecting the Great Barrier Reef. Approximately 16% of respondents felt this technique would likely be adopted.

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Source: www.newscientist.com

Saturn’s Moon Titan Could Harbor an Unforeseen Blend of Hydrogen Cyanide and Hydrocarbons

Titan serves as an intriguing subject for in-depth investigations of organic chemistry under unusual conditions. This Saturnian moon is abundant in nonpolar hydrocarbons like ethane and methane, alongside hydrogen cyanide (HCN), a highly relevant small polar molecule in prebiotic chemistry. Recent studies show that these notably polar compounds can mix at low temperatures, creating structures that challenge traditional chemical theories.

Artistic rendering of Kraken Mare, Titan’s extensive ocean of liquid methane. Image credit: NASA’s John Glenn Research Center.

Hydrogen cyanide is commonly found in the astrochemical landscape and has been detected in numerous celestial bodies, including the interstellar medium, comets, planets, moons, and dwarf planets.

This molecule ranks as the second most prevalent product anticipated from Titan’s atmospheric chemistry.

Dr. Martin Rahm, a researcher from Chalmers University of Technology, stated: “These remarkable discoveries enhance our understanding of something vast—a moon comparable in size to Mercury.”

In laboratory experiments, Rahm and his team combined hydrogen cyanide with methane and ethane at temperatures as low as 90 K (around -180 degrees Celsius).

At this temperature, hydrogen cyanide forms crystals, while methane and ethane exist as liquids.

Using laser spectroscopy to analyze these mixtures at an atomic level, researchers found that while the molecules remained intact, changes were still occurring.

To uncover what was happening, they conducted extensive computer simulations to explore thousands of potential molecular arrangements in the solid phase.

Ultimately, they discovered that the hydrocarbons infiltrated the hydrogen cyanide crystal lattice, leading to the formation of a stable new structure termed a cocrystal.

“The identification of unexpected interactions between these substances may influence our understanding of Titan’s geology and unique features such as lakes, oceans, and sand dunes,” Dr. Rahm explained.

“Moreover, hydrogen cyanide could be crucial in the abiotic synthesis of some life-building blocks, like amino acids for proteins and nucleobases for genetic material.”

“Consequently, our research offers valuable insights into the pre-emergent chemistry of life and the potential for life to evolve in extreme environments.”

of result Published in July 2025. Proceedings of the National Academy of Sciences.

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Fernando Izquierdo Ruiz and others. 2025. Hydrogen cyanide and hydrocarbons mix on Titan. PNAS 122 (30): e2507522122; doi: 10.1073/pnas.2507522122

Source: www.sci.news

New Fossil Indicates Paranthropus Boisei May Have Crafted Tools

Paleoanthropologists have discovered and analyzed a partial hominin skeleton consisting of limb bones that are unmistakably linked to human skull components. Paranthropus boisei, an early hominin species that existed in East Africa between 2.3 and 1.2 million years ago, exhibits characteristics of manipulation and bipedal adaptations similar to those found in the genus homo. Furthermore, the hand morphology of this species shows convergence with gorillas in a way that supports manual food processing, potentially enabling strong gripping abilities akin to those required for climbing trees.

Paranthropus boisei. Image credit: © Roman Yevseyev.

The earliest members of the genus homo were known to have manufactured and utilized stone tools.

However, stone tools dating back 3.3 million years and Oldowan artifacts from 3 million years ago were found at Lomekwi. These discoveries at two locations in Nyayanga, Kenya, have reignited discussions surrounding the potential use of tools by other species.

“When Mary Leakey uncovered the OH 5 skull, Paranthropus boisei was discovered alongside Oldowan stone tools, leading this stone tool to be labeled the ‘oldest stone tool maker yet found,'” stated Dr. Carrie Mongul from Stony Brook University and her team.

“The debate over whether Paranthropus made and used tools has continued since, largely due to the absence of definitive hand bones that can be assigned to this genus.”

In a recent study, the researchers investigated partial human skeletons uncovered between 2019 and 2021 at Koobi Fora, east of Lake Turkana in Kenya.

The specimen, designated KNM-ER 101000, is estimated to be slightly over 1.52 million years old.

The teeth and skull of this specimen align with previous records of Paranthropus boisei fossils.

“KNM-ER 101000 provides the first hand and foot bones definitively linked to human teeth and skull of Paranthropus boisei,” reported the researchers.

Characteristics of KNM-ER 101000’s hands resemble both modern humans and African apes.

For instance, the ratio of thumb to finger length indicates that Paranthropus boisei likely had grip strength and dexterity comparable to that of humans, although they probably did not possess a precise pinch grip.

In contrast, some hand bones bear similarity to those of gorillas, suggesting that Paranthropus boisei may have had a strong grip beneficial for climbing.

“The findings imply that Paranthropus boisei could create and utilize tools to some extent, while also supporting the proposed distinction in dietary adaptations between Paranthropus and homo,” noted the scientists.

“Besides shedding light on less recognized aspects of postcranial functional anatomy in Paranthropus, this discovery highlights broader trends in the evolution of human hands and tool usage.”

The results of this research were published in a new paper in the journal Nature on October 15th. Read the article here.

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CS Mongul et al. A new fossil reveals aspects of the human hand in Paranthropus boisei. Nature published online October 15, 2025. doi: 10.1038/s41586-025-09594-8

Source: www.sci.news

Ultracold Atoms May Investigate Relativity in the Quantum Realm

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Spinning ultracold atoms could uncover the limits of Einstein’s relativity

Shutterstock / Dmitriy Rybin

Small Ferris wheels made from light and extremely chilled particles could enable scientists to investigate elements of Albert Einstein’s theory of relativity on an extraordinary level.

Einstein’s special and general theories of relativity, established in the early 20th century, transformed our comprehension of time by illustrating that a moving clock can tick slower than a stationary one. If one moves rapidly or accelerates significantly, time measured will also increase. The same applies when an object moves in a circular path. While these effects have been noted in relatively large celestial entities, Vassilis Rembesis and his team at King Saud University in Saudi Arabia have developed a method to test these principles on a diminutive scale.

By examining rotation and time at the molecular level (atoms and molecules), they explored ultracold regions, just a few millionths of a degree above absolute zero. In this domain, the quantum behavior and movement of atoms and molecules can be meticulously controlled with laser beams and electromagnetic fields. In 2007, Rembesis and his colleagues formulated a technique to tune a laser beam to trap atoms in a cylindrical form, allowing them to spin. They refer to this as an “optical Ferris wheel,” and Rembesis asserts that their new findings propose that it can be used to observe relativistic time dilation in ultracold particles.

Their predictions indicate that nitrogen molecules are optimal candidates for investigating rotational time delays at the quantum level. By considering the movement of electrons within them as the ticks of an internal timer, the researchers detected frequency changes as minuscule as 1/10 quintillion.

Simultaneously, Rembesis noted that experiments utilizing optical Ferris wheels have been sparse up until now. This new proposal opens avenues for examining relativity theory in uncharted conditions where new or surprising phenomena may emerge. For instance, the quantum characteristics of ultracold particles may challenge the “clock hypothesis,” which states how a clock’s acceleration influences its ticking.

“It’s crucial to validate our interpretations of physical phenomena within nature. It’s often during unexpected occurrences that we need to reevaluate our understanding for a deeper insight into the universe. This research offers an alternative approach to examining relativistic systems, providing distinct advantages over traditional mechanical setups,” says Patrick Oberg from Heriot-Watt University, UK.

Relativistic phenomena, such as time dilation, generally necessitate exceedingly high velocities; however, optical Ferris wheels enable access to them without the need for impractically high speeds, he explains. Aidan Arnold from the University of Strathclyde, UK adds, “With the remarkable accuracy of atomic clocks, the time difference ‘experienced’ by the atoms in the Ferris wheel should be significant. Because the accelerated atoms remain in close proximity, there is ample opportunity to measure this difference,” he states.

By adjusting the focus of the laser beam, it may also become feasible to manipulate the dimensions of the Ferris wheel that confines the particles, allowing researchers to explore time-delay effects for various rotations, as noted by Rembesis. Nevertheless, technical challenges persist, including the need to ensure that atoms and molecules do not heat up and become uncontrollable during rotation.

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Source: www.newscientist.com

The Level of Happiness Required to Reap Health Benefits

On average, do you feel happier than 2.7 out of 10?? And does your country’s population score high as well? Good news! According to a new study, your community is happy enough to enjoy significant health advantages.

The study, published in Medical Frontier, found that countries with a Life Ladder score exceeding 2.7 out of 10—a global indicator of well-being—experienced markedly lower mortality rates from non-communicable diseases (NCDs) like heart disease, cancer, asthma, and diabetes.

These findings indicate that while happiness and health are interconnected, nations need to progress beyond this well-being threshold for citizens to fully realize these benefits.

For each 1% rise in well-being above the 2.7 threshold, deaths from non-communicable diseases (NCDs) declined by an average of 0.43%. This implies that even slight increases in happiness can result in tangible health improvements.

In the United States, where the average happiness score stands at 6.96, such an increase could translate to nearly 11,500 fewer NCD-related deaths annually.

“Happiness is not merely a personal feeling; it serves as a measurable public health resource,” stated Yulia Iuga, a professor at the University of Alba Iulia in Romania and the study’s lead author.

The research analyzed well-being data from 123 countries collected between 2006 and 2021, comparing NCD mortality rates among adults aged 30 to 70.

Researchers employed the Life Ladder, a global tool for assessing subjective well-being that asks individuals to rate their lives on a scale of 0 to 10, where higher scores represent greater satisfaction.

“You can think of the life ladder as a straightforward happiness scale from zero to 10, with zero indicating the worst life and 10 the best,” Iuga clarified. “An appropriate descriptor for the 2.7 threshold could be ‘barely coping.'” Currently, only one nation falls below this benchmark: Afghanistan, with a happiness score of 1.36. Meanwhile, Finland leads the world ranking with a Life Ladder score of 7.74, followed by Denmark (7.52) and Iceland (7.51).

Many studies link health and happiness – Credit: Getty

Iuga noted that the findings suggest the benefits of happiness are likely to continue expanding indefinitely. “There’s no downside to being excessively happy,” she emphasized. “This study found no point at which the health benefits began to taper off or reverse.”

Iuga further indicated that policies aimed at enhancing population well-being can foster self-sustaining cycles of health improvement. In essence, better health boosts happiness, which in turn encourages further health gains.

Read more:

Source: www.sciencefocus.com

Orionids Peak Tonight: Viewing Shooting Stars from Halley’s Comet

The Orionid meteor shower will soon light up the night sky once again.

This year’s event is anticipated to be particularly stunning, as the peak of the Orionid meteor shower in 2025 aligns with the new moon night, making the sky notably darker.

You don’t require any special gear to observe meteor showers, making it an excellent introduction to stargazing. All you need are your eyes and a clear, dark sky.

Here’s all the essential information to enhance your viewing experience.

When is the Orionid meteor shower tonight?

The 2025 Orionid meteor shower will reach its peak during the night of October 21-22 in the US and UK, but you can catch glimpses of it from October to November.

This meteor shower is relatively prominent. Under optimal conditions, you might see 10 to 20 meteors each hour, though realistically you may spot one roughly every 10 minutes.

What makes the 2025 Orionids especially remarkable is the coincidence with the new moon, allowing for darker skies and visibility of fainter meteors.

Meteors can be seen throughout the night, but many fade below the horizon in the evening. For a better view, wait until after midnight when they will be higher in the sky.

However, the key factor in your viewing experience will be the weather. Keep an eye on the forecast for any breaks in the cloud cover. Even if conditions aren’t ideal, you might catch some meteors if the sky is partly clear.

Don’t fret if the weather doesn’t seem promising on the peak night. You should still see plenty of meteors around October 21st.

How can you see the Orionid meteor shower in 2025?

Meteor showers provide a wonderful shared experience—invite your friends and family! – Credit: Getty

The ideal way to observe a meteor shower is to venture to the darkest location available. Escaping the light pollution of urban areas is your best bet (ensure you have permission and stay in a safe area after dark).

If you can’t get out of the city, try to avoid any direct light sources, whether that’s at your local park or a corner of your garden shielded from streetlights by a fence.

Instead of focusing on one specific direction, aim to take in as much of the sky as possible. Sun loungers make it comfortable to lie back and gaze upwards without straining your neck. Remember to dress warmly and bring along some snacks.

Leave your telescope at home; for meteor watching, your eyes are the best tool you have.

Give your eyes about 20 minutes to adjust to the darkness. Be cautious—any brief exposure to bright light, including your phone, can reset this adjustment.

Now, keep looking up and be patient. Eventually, you should start to see meteors streaking across the sky.

What is a meteor shower?

The Orionid meteor shower is a result of Halley’s Comet, which orbits the inner Solar System approximately every 75 years (its next visit is slated for 2061). As the comet passes, it leaves behind a trail of dust and debris.

Every year, Earth passes through this debris stream, causing tiny particles to collide with our atmosphere at incredible speeds of 70 km (41 miles) per second. This collision heats up the air, creating bright flashes of light known as meteors or shooting stars.

Why are they called the Orionid meteor shower?

Orion is one of the brightest constellations visible in the northern sky – Credit: Getty

The shower derives its name from the fact that all meteors appear to radiate from the constellation Orion.

If you track an Orionid meteor’s path, you’ll find it leads back to this particular constellation.

Orion can be easily recognized by the three bright stars that form its well-known belt in the southern sky. If you’re unsure of what to look for, consider downloading a stargazing or astronomy app to assist you.

Additionally, you might spot meteors that do not originate from the Orion constellation. If so, congratulations! You’ve encountered a stray meteor that coincidentally entered Earth’s atmosphere during the shower.

read more:

Source: www.sciencefocus.com

Experiencing Life Without Tech: Insights from the AWS Outage

Workers were sent home, examinations were postponed, coffee machines required manual activation, and users of language apps feared that their hard-earned progress might be lost due to Monday’s global outage of Amazon Web Services. Meanwhile, some brushed off their temporary technological difficulties.

A malfunction in the AWS cloud service disrupted apps and websites for millions worldwide, impacting over 2,000 companies, including Snapchat, Roblox, Signal, the language app Duolingo, and various Amazon-owned businesses.

While many sites were operational again within a few hours, several continued to experience problems throughout the day. By Monday evening, Amazon reported that all cloud services had “returned to normal operations.”

However, amid the chaos disrupting essential services globally, there was an unexpected twist.

Amazon employees shared videos on TikTok enjoying a slow workday. Some were dancing in quiet warehouses, while others informed CNN that they had been dismissed.


“Those of us working at Amazon Flex have been sent home because the system can’t check us in or release us for pay. Due to this outage, we are uncertain if the 80 of us here will receive compensation,” James, a Texas resident, shared with the network.

Tiffini from Florida mentioned she had planned to start her Amazon delivery shift at 3:30 a.m., but the system was down. “I submitted a ticket, but due to issues with Amazon’s system this morning, I still don’t know if I’ll be paid for the missed block.”

Other social media users reported delays in medical and veterinary appointments, while some customers using Amazon’s virtual assistant Alexa encountered smart home disruptions.

“I use an Alexa-enabled smart plug to control my room lamps,” Christina, who requires crutches, told CNN. “During the outage, my smart plugs stopped responding. Before I could figure out the problem, I tried to reset one and ended up failing. Now they don’t work at all.”

Nonetheless, some Alexa users downplayed the incident.

“Because of the Amazon outage, Alexa wasn’t functional this morning, so I had to stumble out of bed in the dark, head to the kitchen, and manually turn on the coffee maker. I can’t live like this. You all can do without me,” one user shared. Posted by user X.

“I had to turn the lights on manually without Alexa’s assistance. It was a rough beginning to the day,” another user remarked on Reddit.

Many devoted Duolingo users, who track their consecutive practice days, were anxious about their progress being affected.

Some threatened to “riot” if their practice streaks were interrupted, others lamented that streaks exceeding 900 days had reset to zero, while one user on X targeted Amazon founder and CEO Jeff Bezos, saying, “What if I lost my 1,300-day Duolingo streak due to AWS? [Amazon Web Services] If the power goes out, I’ll personally throw an egg at Bezos’ bald head.”

Duolingo offered reassurance to users on Tuesday. Your streaks will be safe!


Conversely, for some individuals, web services like Canvas – an educational platform – became a reason for joy.

“I can’t grade on Canvas since Amazon Web Services is down. It’s so enjoyable not being able to work lol,” one BlueSky user commented.

“I can’t access midterm exams,” remarked one Reddit user. “I’m having a fantastic day.”


Source: www.theguardian.com

Instagram’s Ongoing Commitment to Youth Safety: Will the New “PG-13” Guidelines Make a Difference?

For months, Instagram has faced challenges in persuading parents, advocates, and officials that it is a safe environment for children, despite increasing evidence indicating otherwise. Now, the platform is rolling out another safety feature intended to protect teens. Yet, given its track record, parents remain skeptical.

Beginning this week, all users under 18 will automatically be categorized for ages 13+ and their feeds will be restricted to content suitable for the U.S. PG-13 movie rating.

However, Instagram’s previous unfulfilled commitments make this latest content restriction feel like mere window dressing—an illusion of action without genuine effectiveness.

The company has accrued substantial profits while advocacy groups have long cautioned against exposing minors to inappropriate content and individuals. $100 billion annually is what it reports in profits. Meta’s own estimates suggest that about 100,000 children using Facebook and Instagram face online sexual harassment daily. This is concerning, especially considering that as of July 2020, internal communications revealed that the measures to prevent child grooming on the platform were, at best, “between zero and negligible.” The lawsuit in New Mexico claims that Meta’s social networks, including Instagram, have essentially become a haven for child predators. (Meta refutes these core allegations, claiming the lawsuit is ‘unfair’.)

Last year, the firm finally enacted mandatory Instagram accounts for teenagers. However, a recent study led by a whistleblower revealed that 64% of the new safety features designed for teens were ineffective.

Research indicates that 47% of young teen users on Instagram encounter unsafe content, and 37% of users aged 13 to 15 receive at least one unsafe piece of content or unwanted message weekly. This includes “approximately 1 in 7 users viewing self-harm content, unwanted sexual content, discriminatory content, or substance-related content every week.”

“These failures showcase a corporate culture at Meta that prioritizes engagement and profit over safety,” stated Andy Burrows, CEO of the UK’s Molly Rose Foundation, which advocates for stronger online safety legislation, as part of the investigative team. BBC reported. A spokesperson for Meta countered that the study “misrepresents our commitment to empowering parents and protecting youth, and mischaracterizes the functionality of our safety tools and their use by millions of parents and youth.”

Concurrently, measures introduced last year followed a significant moment for Meta’s public perception. In January 2024, the leaders of the world’s major social media firms were summoned to the U.S. Senate to discuss their security policies. Meta CEO Mark Zuckerberg issued an apology to parents whose children allegedly endured harm from social media.

Despite Instagram’s lengthy struggle to address these concerns, it appears to continually place children at risk, only to issue apologies afterward. On Monday, Reuters reported that it has been found in company-specific research that teens who frequently felt negative about their bodies on Instagram encountered three times more “eating disorder-related content” than their peers. Alarmingly, technology companies and social media platforms have become so entrenched in everyday life that it’s nearly impossible to engage with society without them, particularly for children.

So, what is the resolution? Primarily, we must acknowledge online spaces as extensions of the real world, rather than merely digital counterparts. Social media platforms replicate real-life violence and can cause other tangible harms, putting children at a higher risk.

It’s essential for lawmakers to require these companies to incorporate safety measures into their design processes rather than treating them as an afterthought. Equally vital is for parents to educate their children on online safety, just as they would about physical safety in public.

The technology developed by these profit-driven companies is pervasive. If we cannot rely on them to safeguard our most vulnerable users, it falls upon us to ensure our own protection.

Source: www.theguardian.com

Just Kidding, Meatbag! Channel 4’s AI Presenter Delivers High Demands on Multiple Levels

LTonight’s Dispatch was called “Will AI take my job?” The presence of a question mark usually suggests a negative answer, but this time it feels different. The lurking threat of AI taking over our roles is sobering to ponder.

The film claims that 8 million jobs in the UK are potentially at risk due to AI outsourcing. Occupations including call center agents, translators, and graphic designers—essentially everyone except for masseuses and scaffolders—may soon face redundancy from rapidly advancing technology, despite its dire environmental consequences. My lifespan may be limited, and it’s clear I’ll likely be replaced by a prompt from ChatGPT instructing, “Be histrionic and outraged about what’s on TV.” Grok can even generate a signature image of a comically smug egg to accompany it. Nobody surpasses this level of intelligence.

But why would anyone tune in to Dispatches knowing that AI could render us all obsolete? There wasn’t much to be enthusiastic about unless they were disturbingly motivated to bolster their darkest fears about humanity’s future. However, the film anticipated this sentiment and provided its own clever twist. The segment was introduced by a journalist named Aisha Gavan, who, shockingly, was AI-generated from the start.

Indeed, Channel 4 has fully embraced Tilly Norwood. Gavan was devoid of humanity; she was entirely a computer-generated entity. Yet, despite being mere pixels and code, her hosting was surprisingly convincing. Sure, she had an unfeeling gaze and struggled to articulate sibilant sounds correctly, but she appeared largely human and maintained the stilted pacing typical of TV documentaries. Quite the amusing situation! Who did you consider an authority? Not even a real person! Just kidding, flesh vessel.

The episode itself was fairly well-crafted, featuring four experts—a doctor, a lawyer, a musician, and a photographer—pitted against the capabilities of AI. The overall conclusion seemed to imply that while humans might be superior, AI excels in speed and cost-efficiency. Since greed drives every industry, we’re all in deep trouble.

Some of the technology discussed made sense, like a diagnostic tool capable of assessing a patient in half the time of a typical GP. This could potentially aid healthcare professionals already overloaded by systemic failures. But who really needs an AI photographer? The mission of AI is not to automate creativity but rather to alleviate mundane tasks in our lives. The emergence of AI photographers hints at a daunting future where we could be consigned to producing low-quality art endlessly spewed out by machines.

Ultimately, the spotlight was on Aisha Gavan, touted as Britain’s first AI TV presenter. Honestly, it felt like Channel 4 was trying to have both benefits and fun at once. Not only did they showcase their shiny new toy, but they also managed to lampoon the very technology that generated her. What a clever stunt!

It’s tough to view the film as anything but a stern warning for Channel 4’s other presenters. Hey Krishnan Guru Murthy, you’d better stop grumbling about office snacks or face replacement by an animated mannequin programmed to deliver scripts! Kevin MacLeod, no contract disputes, as a virtual avatar can perform your role without ever needing a break.

And let’s not forget the environmental implications involved. It would have been refreshing if Dispatch wrapped up with Gavan detailing the water consumption required to operate the data center that produced her, especially given Channel 4’s long-standing pledge to reach net zero.

In summary, it was a profoundly challenging watch on various levels. The situation will likely worsen as AI technology continues to advance at a staggering pace. Three years from now, while you’re foraging for bugs to nourish your family, you could have a ChatGPT providing you precise, bullet-point critiques of shows presented by AI-generated hosts. Yet, it was enjoyable while it lasted, wasn’t it?

Source: www.theguardian.com

Vampire: The Masquerade – Bloodlines 2 Review: A Captivating Noir Experience

YYou awaken as an ancient and formidable vampire in the basement of a crumbling building in Seattle, with no recent memories and a peculiar seal on your hand. The first thing you do is provoke the cop who spots you. In a swift movement, you slam him against the wall, blood painting the bricks. A frenzied display of fangs follows as you seek favor with the local vampire court, while viciously battling hostile undead and their ghouls, all while attempting to remain hidden from the unsuspecting mortals in this sultry city.

Yet, this is also a detective narrative. Young night stalkers share your mind, including a voice named Fabian who speaks like a 1920s gumshoe, likely because he once was one. Unlike you, Fabian isn’t violent. He collaborates with human police and the vampire underbelly, extracting the blood of willing donors and wielding his mind-reading powers to uncover murders. These two narratives present distinctly different gameplay experiences in the same setting. Unfortunately, Bloodlines 2 feels awkwardly pieced together. Having just indulged in AMC’s Interview with the Vampire series, the juxtaposition is striking. One provides a thrilling, sexual, and clever adaptation of vampire lore, while the other is lacking.

“The interactions with the people in Seattle were really puzzling.” … Bloodlines 2. Photo: The Chinese Room/Paradox Interactive

Notably, this vampire tale appears to be under a curse. The original Bloodlines game, a cult classic RPG released in 2004, took more than a decade to spawn a sequel. Development for Bloodlines 2 commenced in 2015 at Hardsuit Labs in Seattle, led by writers from the first game. However, the creative lead was dismissed in 2020, and another writer was involved in a now-resolved cheating scandal. By 2021, a new developer, The Chinese Room, took over the project. The outcome is an intriguing patchwork, with The Chinese Room integrating elements from Hardsuit’s version into a coherent 25-hour narrative that, while not entirely resolved, is mostly understandable.

For instance, the vampire abilities you can acquire are displayed on a large screen, intended to offer multiple approaches to gameplay, such as seduction, coercion, and manipulation. Nonetheless, there’s little incentive to learn more skills as you begin immensely powerful, gaining some of the most enjoyable mind control and dark powers within the first few hours. When I attempted to utilize these abilities creatively, such as possessing dangerous prey on the street or probing someone’s mind for interrogation, the game frequently denied my attempts.

While the vampire interactions held intrigue, the encounters with Seattle’s humans were utterly baffling. Walking down the street, I heard sex workers yell, “I have to pay my school fees!” to no one in particular. A businessman on a bench initially asked, “Do you want to start a business together? A sexy business?” before he commenced following me around, exclaiming, “I can’t wait to have sex!” until my annoyance grew and I ended up consuming him. Although vampires may view mortals as inconsequential puppets, this felt excessively bizarre.

“Some of the most awkward first-person combat I’ve played in decades”…Bloodlines 2. Photo: The Chinese Room/Paradox Interactive

This odd and misplaced behavior from non-player characters further amplifies the feeling of Bloodlines 2 being a product of the late ’00s. Not only does the animation appear dated, but it also conjures memories of the clunky yet captivating first-person games emerging since Deus Ex in 2000. While gliding across Seattle’s rooftops at unnatural speeds is entertaining, much of the gameplay entails traversing the city and speaking with various characters. However, when facing ghouls—of which there are plenty—you’re thrust into some of the most awkward first-person combat I’ve experienced in years. I found it so tedious that I opted to lower the difficulty after a few hours to expedite the monotonous skirmishes.

Hidden within is an acceptable vampire story. Engaging conversations with dangerous fellow vampires represent the most compelling aspect of Bloodlines 2. I appreciated several locations in Seattle, particularly the dive bars pulsating with goth music. The Chinese Room has managed to transform a troubled game development saga into something playable and somewhat engaging. However, as time passed, my motivation to continue stemmed more from curiosity than genuine enjoyment.

Source: www.theguardian.com

Bryan Cranston Appreciates OpenAI’s Efforts to Combat Sora 2 Deepfakes

Bryan Cranston expressed his “gratitude” to OpenAI for addressing deepfakes of him on its generative AI video platform Sora 2. This action follows instances where users managed to create his voice and likeness without his permission.

The Breaking Bad actor has voiced concerns to actors’ union Sag Aftra after Sora 2 users generated his likeness during the platform’s recent launch. On October 11th, the LA Times reported that in one instance, “a synthetic Michael Jackson takes a selfie video using an image of Breaking Bad star Bryan Cranston.”


To appear in Sora 2, living individuals must provide explicit consent or opt-in. Statements following the release from OpenAI confirmed it has implemented “measures to block depictions of public figures” and established “guardrails to ensure audio and visual likenesses are used with consent.”

However, upon Sora 2’s launch, several articles emerged, including those from the Wall Street Journal, Hollywood Reporter, and LA Times, which reported that OpenAI instructed several talent agencies that if they didn’t want their clients’ or copyrighted material to be featured in Sora 2, they needed to opt-out instead of opt-in, causing an uproar in Hollywood.

OpenAI contests these claims and told the LA Times its goal has always been to allow public figures to control how their likenesses are utilized.

On Monday, Cranston released a statement via Sag Aftra thanking OpenAI for “enhancing guardrails” to prevent users from generating unauthorized portraits of himself.

“I was very concerned, not only for myself but for all performers whose work and identities could be misappropriated,” Cranston commented. “We are grateful for OpenAI’s enhanced policies and guardrails and hope that OpenAI and all companies involved in this endeavor will respect our personal and professional rights to control the reproduction of our voices and likenesses.”

Hollywood’s top two agencies, Creative Artists Agency (CAA) and United Talent Agency (UTA), which represents Cranston, have repeatedly highlighted the potential dangers Sora 2 and similar generative AI platforms pose to clients and their careers.

Nevertheless, on Monday, UTA and CAA released a joint statement alongside OpenAI, Sag Aftra, and the Talent Agents Association, declaring that what transpired with Cranston was inappropriate and that they would collaborate to ensure the actor’s “right to determine how and whether he can be simulated.”


“While OpenAI has maintained from the start that consent is required for the use of voice and likeness, the company has expressed regret over these unintended generations. OpenAI has reinforced its guardrails concerning the replication of voice and likeness without opt-in,” according to the statement.

Actor Sean Astin, the new chair of SAG Aftra, cautioned that Cranston is “one of many performers whose voices and likenesses are at risk of mass appropriation through reproduction technology.”

“Bryan did the right thing by contacting his union and professional representatives to address this issue. We now have a favorable outcome in this case. We are pleased that OpenAI is committed to implementing an opt-in protocol, which enables all artists to decide whether they wish to participate in the exploitation of their voice and likeness using AI,” Astin remarked.

“To put it simply, opt-in protocols are the only ethical approach, and the NO FAKES law enhances our safety,” he continued. The Anti-Counterfeiting Act is under consideration in Congress and aims to prohibit the production and distribution of AI-generated replicas of any individual without their consent.

OpenAI has openly supported the No FAKES law, with CEO Sam Altman stating the company is “firmly dedicated to shielding performers from the misuse of their voices and likenesses.”

Sora 2 permits users to generate “historical figures,” which can be broadly defined as both well-known and deceased individuals. However, OpenAI has recently acknowledged that representatives of “recently deceased” celebrities can request for their likeness to be blocked from Sora 2.

Earlier in the month, OpenAI announced its partnership with the Martin Luther King Jr. Foundation to halt the capability of depicting King in Sora 2 at their request as they “strengthened guardrails around historical figures.”

Recently, Zelda Williams, the daughter of the late actor Robin Williams, pleaded with people to “stop” sending her AI videos of her father, while Kelly Carlin, the daughter of the late comedian George Carlin, characterized her father’s AI videos as “overwhelming and depressing.”

Legal experts speculate that generative AI platforms could enable the use of deceased historical figures to ascertain what is legally permissible.

Source: www.theguardian.com

Garmin Fenix 8 Pro Review: Integrated LTE and Satellite Messaging Without a Phone

The newest upgrade to Garmin’s leading Fenix adventure watch introduces potentially life-saving capabilities: independent communication and emergency messaging through 4G or satellite.


The Fenix 8 Pro builds upon the already remarkable Fenix 8, incorporating new cellular technology as well as an advanced microLED display in a special edition of the watch. As Garmin’s flagship model, it’s designed to be your comprehensive tool for exploration and tracking.

This ambitious design comes at a high cost, starting from £1,030 (€1,200, $1,200, AU$2,300) for the 47mm OLED variant, and £1,730 (€2,000/$2,000/AU$3,399) for the 51mm model with a microLED screen, nearly double the price of the standard Fenix 8.

You get remarkable value with top-tier exercise, activity, and adventure tracking capabilities. If you find yourself lost without your phone, an extensive offline map of the world will guide you back. It boasts a stunning, large, clear, and exceptionally bright touchscreen.


The Fenix 8 Pro is thicker and heavier than the regular Fenix 8 by 2.2 mm and 4 g, respectively, giving it a rather bulky presence on the wrist. Photo: Samuel Gibbs/The Guardian

The Fenix 8 Pro is offered exclusively in case sizes of 47mm or 51mm, lacking the smaller 43mm option available in other Garmin models, making it suitable for larger wrists. Nevertheless, the 47mm OLED version we examined supplies an additional day of battery life for smartwatch usage with the screen continuously on, lasting 8-9 days between charges.

Messaging, Calls, and Live Tracking Without Phone

Garmin utilizes its own inReach LTE (4G) and satellite subscription services, rather than depending on a watch plan linked to a smartphone provider like other smartwatches. However, unlike satellite-enabled devices from Apple and Google, emergency SOS messaging isn’t offered for free.

Plans begin at £7.99 per month or its equivalent, offering unlimited LTE text and voice messaging, calls, and services. LiveTrack enables location sharing, allowing friends and family to monitor your whereabouts while engaging in activities like running or cycling, and providing emergency satellite SOS messaging as well.


Establishing and activating an inReach subscription can be relatively time-consuming, but it’s a one-time process. Photo: Samuel Gibbs/The Guardian

Satellite check-ins and text messages incur extra costs, escalating to an unlimited plan of £50 monthly for higher-tier options that provide various satellite allowances. The watch includes a 30-day free trial enabling you to test the service.

Once configured, simply step outside without your phone, and your watch will connect to LTE. While it can’t stream music, you can make calls, send texts, and stay in touch with loved ones.


Messages—including texts, reactions, audio messages, and transcriptions—will display on your watch as well as in the recipient’s Garmin Messenger app. Photo: Samuel Gibbs/The Guardian

When you send a text, Garmin transmits an SMS from a random number, and the recipient can reply directly to your watch. Install the Garmin Messenger app to send and receive both text and voice messages as well as making voice calls. Recipients don’t need a Garmin account; a phone number is all that’s required to register for text messaging.

Messaging on the smartwatch functions adequately, but typing on the small onscreen keyboard can be slow. It also includes customizable quick replies for faster interactions. Voice messages and calls work fine, though the quality may not be ideal for lengthy conversations.

LiveTrack is an especially valuable feature. You can configure it to automatically send a link to select contacts when you start an activity, allowing them to track your real-time location on a map. This feature is fantastic for monitoring progress during races and primarily acts as a safety measure for someone you trust to know your whereabouts. The actual location may experience slight delays when transitioning in and out of a strong LTE signal, but it generally performs well.


To transmit a satellite message, your watch must be oriented correctly, with a clear view of the sky. Photo: Samuel Gibbs/The Guardian

All these features are accessible on other Garmin watches as long as you have your phone, but in locations where LTE coverage is absent, the Fenix 8 Pro activates satellite communication for sending texts, location check-ins, and emergency SOS notifications.

The guide provides instructions on how to establish a line of sight to a satellite and to send and receive messages within approximately 10 to 30 seconds. While this function is remarkably user-friendly and can prove to be a critical lifesaver, it’s essential to understand that satellite coverage is confined to the continental U.S., most of Canada, and much of Europe, excluding certain regions of Scandinavia above 65 degrees north latitude.

Sustainability

Watches are typically optionally repairable as explained on the support site. The battery is rated to retain at least 90% of its initial capacity after two years of weekly recharging. Currently, this model contains no recycled materials. Garmin provides a recycling program for new purchases.

Price

Pricing for the Fenix 8 Pro begins at £1,029.99 (€1,199.99/$1,199.99/A$2,299). Optional Garmin inReach subscription plans are available starting at £7.99 (€9.99/$7.99/A$13.50).

Verdict

The Fenix 8 Pro enhances the existing Fenix 8, transforming it into an exceptional adventure watch by adding LTE capabilities for messaging, calling, and LiveTrack, alongside satellite messaging, check-ins, and emergency SOS features when a signal is unavailable.

The result is an even more powerful adventure tool for those seeking to go phone-free. If you’re looking to have someone monitor your safety while you’re out at night or in remote areas, Garmin provides this capability without the need for additional devices.

While it is liberating to venture outdoors without your phone, this convenience comes with a hefty price tag, both in terms of the watch’s significant cost and the ongoing subscription fee for the inReach service. At least it is independent of phone providers, working with any smartphone brand or network.

The Fenix 8 Pro is an excellent choice for those who prefer not to carry the bulk of their phone while running, cycling, or hiking but still want to remain trackable and reachable. For others, it might feel excessive, especially given that the excellent Fenix 8 model is readily available.

Pros: Track everything with LTE and satellite messaging, an ultra-bright OLED display, best-in-class GPS, an integrated torch, phone and offline voice control, over 8 days of battery life, Garmin Pay, complete offline mapping and routes, offline Spotify access, 100m water resistance and 40m diving capability, with both button and touchscreen functionalities.

Cons: High price point, LTE and satellite features require a monthly subscription, limited banking support for Garmin Pay, sluggish voice functionalities, and smartwatch features are comparatively limited compared to Apple/Google/Samsung devices.

Source: www.theguardian.com

This Unusual Optical Illusion Could Reveal Insights into Animal Thought Processes

A recent study reveals that certain optical illusions can deceive some animals, though not all. This emerging research may offer fresh insights into how perception influences survival and evolution in different species.

The optical illusion examined in this research is known as the Ebbinghaus illusion, where two identical circles appear different in size because one is encircled by a larger circle, while the other is surrounded by a smaller one.

When observing the illusion overall, the outer circle misleads our brain into perceiving the inner circle as a different size. However, focusing solely on the inner circles reveals that they are indeed the same.

Our susceptibility to this illusion hinges on how our brains interpret visual information, whether as a cohesive whole or detailed parts.

To investigate how various animals perceive their surroundings, scientists at the University of Vienna in Austria recreated the Ebbinghaus illusion using bait, arranging circles of differing sizes around a central bait area.

The two orange circles are identical, yet the left one seems smaller due to the larger circle surrounding it. Conversely, the right circle appears larger – Credit: Getty Images

Next, they observed the responses of two fish species: guppies (Poecilia reticulata) and ring doves (Streptopelia risoria).

The findings indicated that guppies are reliably deceived by optical illusions, similar to humans; they often preferred to consume fish flakes within a smaller circle, perceiving them as larger food items.

In contrast, ring doves exhibited varying responses; some birds chose millet seeds surrounded by a smaller circle, while others opted for those within a larger circle.

The researchers concluded that these choices highlight how each species is uniquely equipped to interact with its environment and tackle its challenges.

For instance, guppies inhabit shallow tropical rivers, where they encounter flickering lights, thick vegetation, swift predators, and numerous other guppies.

Guppies might be influenced by an illusion, suggesting they perceive their environment contextually rather than focusing on minute details – Credit: Getty Images

Researchers believe that for guppies, quick judgment of which fish are safe in a visually cluttered environment is crucial for survival. Thus, making rapid decisions could be advantageous.

Conversely, wood pigeons spend their lives on the ground, foraging for seeds. For them, noticing fine details could be more beneficial than analyzing the broader scene.

Nevertheless, scientists have observed that some pigeons react as if they are misled by a hallucination, indicating variability within species, much like humans.

Overall, the team concluded that optical illusions can provide a valuable lens through which to explore the diverse perceptions across species.

read more:

Source: www.sciencefocus.com

Millions of Adults Struggle with Hidden ‘Type 1.5’ Diabetes: Here’s What You Need to Know

You might be surprised to discover that diabetes encompasses more than just two types. While Type 1 and Type 2 are well-known, you may have come across Type 1.5, which has recently gained attention.

Type 1.5 diabetes, formally known as Latent Autoimmune Diabetes (LADA), is not a new variant of diabetes but is relatively uncommon. It has been recognized as a distinct type since 1993; comprising 3 to 12 percent of all adult diabetes cases.

Nonetheless, LADA is challenging to diagnose due to its similarities with the more prevalent types, often resulting in misdiagnosis. Recent studies indicate that misdiagnosis occurs frequently, with 14% of individuals diagnosed with type 2 diabetes potentially having LADA.

Like type 1 and type 2 diabetes, LADA is characterized by elevated blood sugar levels, or glucose, in the blood.

Regardless of the diabetes type, symptoms remain consistent. These include intense thirst, frequent urination, fatigue, and unexpected weight loss. The UK’s leading charity against diabetes notes these include the “four T’s”: thirst, toileting, tiredness, and thinness. diabetes uk

If you experience these symptoms, prompt diagnosis is crucial. Left untreated, diabetes can lead to severe complications affecting the kidneys, eyes, feet, and even nerves.

So, if the symptoms are similar across diabetes types, how can healthcare experts discern which type you have? And how does this differentiation influence treatment?

Comparing Type 1.5 Diabetes to Type 1 and Type 2 Diabetes

Diabetes, in its various forms, has affected humans throughout history. Ancient healers in Greece, India, and Egypt frequently mentioned a peculiar symptom: sweet-smelling urine. Thus, the term diabetes derives from the Greek word “diabetes,” meaning to pass, and the Latin word “mellitus,” meaning sweet.

This sweet-smelling symptom arises from the buildup of glucose in the body. Glucose is processed by a hormone called insulin, produced by the pancreas, which converts it into a usable energy source for cells.

Glucose buildup occurs when the body either:

  • Fails to produce sufficient insulin (as in type 1 diabetes)
  • Or does not respond effectively to insulin (as seen in type 2 diabetes)

In both scenarios, the kidneys struggle to reabsorb excess glucose in the bloodstream. When they cannot eliminate glucose effectively, surplus sugar spills into the urine, indicating the presence of disease.

LADA shares numerous traits with these two predominant diabetes types, leaning closer to type 1 than type 2.

Finger prick test provides an immediate overview of blood sugar levels.

One significant reason individuals with type 1 diabetes have insufficient insulin is that their immune system attacks pancreatic cells responsible for insulin production. As these cells decline, the body struggles to maintain glucose levels.

The same is true for LADA. An influx of immune cells targets the pancreas, leading to decreased insulin production and gradually rising blood sugar levels. However, the timeline for the onset of the disease differs.

Type 1 diabetes typically has a rapid onset, often diagnosed in childhood or during a clinical emergency. In contrast, LADA progresses slowly and usually occurs in adults over 30.

As we age, a protective layer known as the periislet basement membrane (BM) develops around insulin-producing pancreatic cells. Current understanding suggests that this layer shields these cells from immune system attacks.

“By the time LADA autoimmunity begins, the pancreas [cells] have formed larger structures that provide better protection against immune attacks.” Sarah Richardson, Professor of Cellular Biomedicine, University of Exeter.

Thus, LADA’s onset resembles type 2 diabetes, which typically manifests in adults. Due to this similarity, up to 14% of individuals diagnosed with type 2 diabetes may actually have LADA.

Significance of Misdiagnosis

The primary treatment for type 2 diabetes is a medication called metformin. Administered in pill form, metformin works in two ways: it not only restricts the liver from absorbing excessive glucose but also enhances the body’s sensitivity to insulin.

However, a clear management strategy for LADA is still not established. While metformin may be prescribed, insulin replacement therapy could also be necessary. If someone has LADA misdiagnosed as type 2 diabetes, they might receive metformin when insulin is the actual requirement.

Taking inappropriate medication over extended periods can elevate blood sugar levels. Chronically high blood sugar can lead to severe complications, including heart disease, stroke, eye issues (retinopathy), foot problems (ranging from increased susceptibility to infections and ulcers to sensory loss), kidney disease (nephropathy), and nerve disorders (neuropathy).

A 2018 study published in diabetes medicine discovered that LADA patients are more likely to develop severe neuropathy compared to those with type 2 diabetes.

LADA can also invoke damage to small blood vessels, termed microvascular disease. A 2020 study indicated that strict glycemic control from the onset of LADA significantly decreases the risk of subsequent microvascular disease.

Consequently, minimizing misdiagnosis rates is vital for individuals with LADA. Fortunately, there are effective methods to distinguish LADA from type 1 and type 2 diabetes.

The first and foremost step a doctor can take is to check for antibodies. These antibodies incorrectly signal the immune system to attack insulin-producing pancreatic cells. Finding at least one antibody suggests the presence of autoimmune diabetes. Elevated antibody levels may indicate a more rapid progression of LADA.

This principle also applies when multiple antibodies are present. In such cases, immediate insulin treatment becomes crucial to help manage blood sugar levels more effectively.

Practitioners may also assess a person’s insulin output. This can be done by measuring a blood protein known as c-peptide, which is produced during insulin synthesis in the pancreas. Elevated c-peptide levels may respond well to metformin. However, if the levels are significantly low or undetectable, immediate insulin therapy should be initiated. In LADA, c-peptide levels tend to diminish over time, and it is recommended to conduct tests every six months.

A person’s body composition can further indicate LADA. Individuals exhibiting symptoms of the “four T’s” (thirst, frequent urination, fatigue, and weight loss) who maintain relatively low fat levels or body weight are generally more inclined to have LADA than type 2 diabetes. Additionally, LADA patients typically possess favorable cholesterol levels, which can aid in refining the diagnosis.

Once an accurate diagnosis is established, LADA can be treated appropriately. It’s critical to reach this point with guidance from healthcare professionals.

Read more:

Source: www.sciencefocus.com

Hubble Space Telescope Captures NGC 3370 Observations

Astronomers utilizing the NASA/ESA Hubble Space Telescope have captured new images of the nearly face-on spiral galaxy NGC 3370.



This Hubble image illustrates spiral galaxy NGC 3370, located approximately 90 million light-years away in the constellation Leo. Image credits: NASA / ESA / Hubble / A. Riess / K. Noll.

NGC 3370 is situated in the constellation Leo, roughly 90 million light-years from Earth.

This galaxy, also known as the Silverado Galaxy, IRAS 10444+1732, LEDA 32207, and UGC 5887, is nearly comparable to our Milky Way in both diameter and mass.

Discovered on March 21, 1784, by German-British astronomer William Herschel, NGC 3370 was the first of its kind to be identified.

Together with NGC 3447 and NGC 3455, it forms part of the NGC 3370 galaxy group.

NGC 3370 contains two types of celestial objects that astronomers find valuable for measuring distances to far-off galaxies: Cepheid variable stars and Type Ia supernovae.

“Cepheid variable stars undergo changes in both size and temperature during their pulsations,” Hubble astronomers explained in a statement.

“Consequently, the brightness of these stars fluctuates over timescales of days to months.”

“This variation reveals a key relationship: the brighter a Cepheid variable star, the slower its pulsation.”

“By timing the pulsation cycle of a Cepheid variable star, we can ascertain its true brightness.”

“When combined with observations of its apparent brightness from Earth, this data enables us to calculate the distance to the star and its galaxy.”

“Type Ia supernovae allow for distance measurements through a single explosive event, as opposed to periodic brightness changes.”

“These explosions occur when a star’s dead core reignites due to a sudden surge of nuclear fusion.”

“They reach similar peak brightness levels, akin to those of Cepheid variable stars, and knowing the intrinsic brightness of a supernova allows us to determine its distance.”

“The observation of both Cepheid variable stars and Type Ia supernovae is crucial for accurately gauging how quickly our universe is expanding.”

Source: www.sci.news