Sagittarius A*: Detection of Hot Gas Emitted from a Black Hole Confirmed

Molecular gas and X-ray emissions around Sagittarius A*, a black hole in the Milky Way.

Mark D. Golsky et al. (CC by 4.0)

Researchers have confirmed that hot winds are emanating from the supermassive black hole at the center of the Galaxy for the first time.

In contrast to many other supermassive black holes throughout the universe, Sagittarius A* (SGR A*) remains relatively subdued. Unlike its more active counterparts that emit vast jets, SGR A* does not produce such striking displays. While many supermassive black holes create winds, which are streams of hot gas that originate near the event horizon, these have never been definitively observed around SGR A*, despite theoretical predictions dating back to the 1970s.

Mark Golsky and Elena Marchikova from Northwestern University, Illinois, utilized the Atacama Large Millimeter/submillimeter Array (ALMA) in Chile to conduct a more detailed study of the cold gas in the innermost region of the Circumnuclear Disk (CND). Their observations revealed an unexpectedly large volume of cold gas and a distinct cone that penetrates through the hot gas.

“To find such a significant amount of cold gas so close to the black hole was surprising,” says Golsky. “Conventional understanding suggested it was unlikely to be there, which is why we hadn’t previously searched for it. When I shared this image, my colleague remarked, ‘We need to investigate this further, as it’s been a puzzle for over 50 years.’”

Golsky and Marchikova’s five years of observations provided a detailed analysis of the innermost part of the CND, mapping cold gases within a vicinity of SGR A* 100 times previous measurements. By simulating and subtracting the bright variability of SGR A*, they could isolate the dim light from the cold gas.

This approach revealed a pronounced cone region nearly devoid of cold gas, and when they overlaid X-ray emissions (produced by the hot gas), a striking correlation emerged. The energy required to propel the hot gas through this cone approximates that of 25,000 suns—far too substantial to originate from nearby stars or supernovae, indicating it likely derives from SGR A* itself. “The energy necessary comes directly from the black hole, confirming the presence of winds originating from it,” Golsky states.

<p>Prior observations have identified expansive gas bubbles, known as Fermi bubbles, situated above and below the galaxy. However, the possibility of these jets reforming remains uncertain. Understanding this wind phenomenon sheds light on why SGR A* shows lower activity and enhances our comprehension of black hole evolution.</p>
<p>The implications of the reduced wind activity surrounding SGR A* are exciting. If verified, findings by <a href="https://scholar.google.com/citations?user=1VNwK9gAAAAJ&amp;hl=en">Ziri Younsi</a> from University College London could offer crucial insights into the nature of the black hole, including its rotational direction. Astronomers have postulated that SGR A* spins perpendicular to the Milky Way plane, implying a need for edge-on observation. However, the inaugural image of a black hole captured by the Event Horizon Telescope in 2022 produced inconclusive data, suggesting a possible in-person orientation.</p>
<p>“The mass of Sagittarius A* is well-defined by current observations, but its tilt angle relative to us remains largely unknown,” explains Younsi. “If these findings are robust, understanding the origins of these matter flows will be genuinely fascinating, as it will provide insights into how material spirals toward the black hole, contributing to our knowledge of galactic evolution.”</p>

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Source: www.newscientist.com

Breakthroughs in Huntington’s Disease: Essential Insights on Gene Therapy

The caudate nucleus is one of the brain regions that gene therapy targets

Kateryna Kon/Science Photo Library

Innovative gene therapy has emerged as the pioneering treatment that effectively slows the progression of Huntington’s disease. While the results are still in their early stages, this method holds significant promise and could even pave the way for new therapies for other neurodegenerative disorders, including Parkinson’s and Alzheimer’s diseases.

How does the treatment function?

The therapy known as AMT-130 specifically targets the abnormal brain proteins associated with Huntington’s disease progression. Those affected by the condition possess genetic mutations that result in the accumulation of huntingtin proteins, which form toxic aggregates in brain cells, leading to cell death. This eventually manifests as memory loss, mobility issues, speech impairment, and various other symptoms.

Therapies from the Dutch biopharmaceutical company Uniqure aim to halt the production of these mutant proteins. The process involves delivering genetic material to brain cells using a harmless virus. This genetic material instructs the cells to produce small RNA molecules called microRNAs that effectively block and eliminate the signals that lead to the generation of toxic proteins. It acts similarly to a molecular stop signal.

Procedures and Location of Treatment

This therapy initially focuses on two specific brain areas impacted by Huntington’s disease: the caudate nucleus and the putamen. These regions are located deep within the brain, requiring doctors to utilize real-time brain imaging to navigate thin catheters into place. The entire procedure duration ranges from 12 to 18 hours, and preliminary results suggest that a single injection may be adequate to permanently reduce levels of mutant huntingtin in the brain.

What is the efficacy of gene therapy?

Initial findings released by Uniqure indicate that gene therapy may slow the advancement of Huntington’s disease by approximately 75%.

The revelation stems from a clinical trial spearheaded by Sarah Tabrizi of University College London, where 17 Huntington patients received high-dose treatment. After three years, researchers noted the deterioration in cognitive function, motor skills, and daily activities compared to a similar group of untreated individuals. Tabrizi remarked that the decline typically observed over a year in untreated patients was instead noted within four years for those receiving treatment. BBC News. Additionally, those treated exhibited reduced levels of proteins associated with brain damage in their cerebrospinal fluid, highlighting the potential of gene therapy in slowing Huntington’s progression.

“These findings reaffirm our conviction that AMT-130 could revolutionize the treatment landscape for Huntington’s disease,” stated Walid Abi-Saad from Uniqure in a press release.

Are there any side effects?

While Uniqure has not provided comprehensive data on the side effects of the treatment, initial reports suggest that the drug appears to be safe and well-tolerated. The most frequently reported side effects included headaches and confusion, which generally resolved with steroid treatment to reduce inflammation.

When will the treatment be accessible?

In a recent press announcement, Uniqure indicated that it anticipates submitting an application to the U.S. Food and Drug Administration early next year, with the potential for product availability as soon as before 2027 with expedited approval.

“However, it is still in the preliminary phase, and further testing is necessary to assess the long-term effects of this new gene therapy and any potential side effects,” noted Zofia Miedzybrodzka from the University of Aberdeen, UK, in a statement.

Could this method assist in treating other brain disorders?

If successful, the gene therapy could facilitate the development of analogous treatments for various neurodegenerative diseases, including Parkinson’s and other forms of dementia, according to David Rubinsztein from Cambridge University. Researchers could manipulate genetic material to target the toxic proteins that cause these conditions. “This could represent a significant breakthrough,” he remarked.

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Source: www.newscientist.com

Webb Observes Sagittarius B2 in an Interstellar Molecular Cloud

Positioned at the core of the Milky Way galaxy, Sagittarius B2 is an immense molecular cloud of gas and dust, boasting around 3 million times the mass of the sun.



The Sagittarius B2 molecular cloud, where stars, gases, and cosmic dust shimmer in near-infrared light, as captured by Webb’s Nircam instruments. Image credits: NASA/ESA/CSA/STSCI/A. GINSBURG, University of Florida/N. Budaiyev, University of Florida/T. Yu, University of Florida/A. Pagan, STSCI.

The distance from Earth to Sagittarius B2 is roughly 27,000 light years, while it sits just 390 light years from the center of the Milky Way.

This is the largest and most active star-forming cloud within our galaxy, accounting for half of the stars birthed in the central region, even though it comprises merely 10% of the material required for star formation in that area.

“Sagittarius B2 is situated just hundreds of light years away from the supermassive black hole located at the galaxy’s center, right at the heart of star formation.”

“Webb’s infrared observations can penetrate some of the dense clouds present, uncovering young stars alongside the warm dust enveloping them.”

“Examining Webb’s findings aids in unraveling the long-standing enigma surrounding the star formation process and why Sagittarius B2 generates stars at a rate surpassing other galaxy centers.”

“Interestingly, one of the most striking elements of Webb’s imagery of Sagittarius B2 is the regions that remain dark.”

“These seemingly vacant areas of space are so tightly packed with gas and dust that even Webb cannot detect them.”

“These dense clouds are the progenitors of future stars and are too young to emit light themselves.”



Webb’s Miri (medium-infrared device) displays the Sagittarius B2 region in medium-red light, revealing bright warm dust. Image credits: NASA/ESA/CSA/STSCI/A. GINSBURG, University of Florida/N. Budaiyev, University of Florida/T. Yu, University of Florida/A. Pagan, STSCI.

With the high resolution and sensitivity of Webb’s Miri (mid-infrared device), this area has been uncovered in remarkable detail, showcasing luminous cosmic dust heated by a massive, young star.

The red area labeled Sagittarius B2 North (located to the right in these Webb images) is among the most molecularly abundant regions known, yet astronomers have never observed it with such clarity before.

The differentiation lies in the longer wavelengths produced, even within the infrared spectrum, and the contrast between images from Webb’s Miri and Nircam (near-infrared camera) makes it evident.

“The luminous gas and dust emerge dramatically in mid-red light, though everything except for the brightest stars vanishes from sight,” the astronomer noted.

“In contrast to Miri, vibrant stars take center stage in Webb’s Nircam images.”

“Further investigations into these stars will yield insights into their masses and ages, aiding astronomers in comprehending the intricacies of star formation within this dense, dynamic galactic core.”

“Has this activity persisted for millions of years? Or has an unknown process triggered it recently?”

“We anticipate that Webb will illuminate the reasons behind the disproportionate star formation centered around galaxies.”

“While there are ample gaseous components in this area, overall productivity is not on par with that of Sagittarius B2.”

“Sagittarius B2 contains only 10% of the galaxy-centric gas but is responsible for 50% of the stars.”

Source: www.sci.news

The World’s Oldest Person Had a Youthful Microbiome and an “Extraordinary Genome.”

Painted alongside scientist Manel Esterer, Maria Blagnas Morela contributed to research aimed at uncovering her secrets of longevity

Manel Esterler

From January 17, 2023, to August 19, 2024, Maria Blañas Morera from Spain was formally recognized as the oldest person in the world until her passing at the age of 117 years and 168 days. To investigate the secrets behind her remarkable longevity, a team of researchers explored her genetics, microbiome, and lifestyle.

When Morera was 116, the researchers gathered samples of her blood, saliva, and stool for genetic analysis. “Her genome was exceptional, enriched with variants known to extend lifespans in other species such as dogs, worms, and flies,” noted team member Manel Esterler at the Josep Carreras Leukemia Research Institute in Barcelona, Spain.

Showing no signs of dementia, Morera also possessed numerous genetic variants that helped maintain low blood lipid levels, protecting her heart and cognitive functions, according to Esteller. “Simultaneously, she lacked genetic mutations linked to conditions such as cancer, Alzheimer’s disease, or metabolic disorders.”

The researchers discovered that her lipid metabolism was one of the most efficient recorded. “Her lipid profile was remarkable, with very low cholesterol,” Esterer mentioned. “This efficiency was tied to her modest diet and genetic traits that enabled the rapid metabolism of damaged molecules.”

Esteller noted that Morela abstained from alcohol and smoking and adhered to a Mediterranean diet comprising vegetables, fruits, legumes, and olive oil, along with three servings of sugar-free yogurt daily.

Further assessments indicated that Morela maintained a robust immune system typically seen in younger individuals, alongside a gut microbiota characteristic of much younger people.

One of the most “astonishing” findings was a high concentration of Actinobacteriota bacteria in her gut, including well-known probiotics like Bifidobacteria. This abundance typically declines with age but tends to increase among centenarians and supercentenarians, offering various anti-aging benefits, such as reducing inflammation.

The researchers believe that her yogurt intake may have continually replenished her levels of Bifidobacteria. “This may suggest that dietary interventions can be linked to prolonged lifespan by influencing gut microbiota, along with preventing obesity and other health issues,” Esterer added.

Lastly, scientists examined whether there was a significant difference between Morela’s biological age and her chronological age by constructing an epigenetic clock based on her DNA methylation. This process involves adding or removing chemical tags that regulate gene expression. “Her biological age appeared 23 years younger than her actual age, contributing significantly to her longevity,” remarked Esterer.

Previous studies indicate that supercentenarians may carry genetic mutations associated with various medical conditions, such as Alzheimer’s disease and cardiovascular issues. Nevertheless, they somehow manage to overcome these obstacles and attain extraordinary lifespans. “There are limited studies on supercentenarians, and many only focus on one aspect, like microbiomes,” explained Esteller. “Our research demonstrates that overcoming such maladies is a blend of advantageous genetics and other elements, including beneficial gut microbiota, delayed biological aging indicated by a youthful epigenome, and lifestyle factors such as avoiding smoking, alcohol, and maintaining a low-fat diet.”

Richard Farragher from the University of Brighton in the UK acknowledged that the study highlights the plethora of assessments available to longevity researchers, cautioning that a case study of one individual could risk being perceived as a scientific “So-So Story.”

He explains that there are two key reasons behind the survival of extremely long-lived individuals: “First, there’s something extraordinary about them, perhaps genetically, and second, survival biases due to their fortunate circumstances,” said Farragher.

If luck plays a role, he asserts that to substantiate her longevity, Morela belonged to a family with a history of long lifespans that wasn’t documented in the study.

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Source: www.newscientist.com

The 6100-Qubit Device: A Major Leap Towards Quantum Computing Advancement

Quantum computers can be developed using arrays of atoms

Alamy Stock Vector

Devices boasting over 6000 qubits are setting new records and represent the initial phase of constructing the largest quantum computer ever.

At present, there isn’t a universally accepted design for creating quantum computers. However, researchers assert that these machines need to incorporate at least tens of thousands of qubits to be truly functional. The current record holder is a quantum computer utilizing 1180 qubits, with Hannah Manetsch from the California Institute of Technology and her team endeavoring to build a 6100 qubit system.

These qubits are made from neutral cesium atoms that are chilled to near absolute zero and manipulated using a laser beam, all arranged neatly on a grid. According to Manetsch, they have fine-tuned the properties of these qubits to enhance their suitability for calculations, although they have yet to carry them out.

For instance, they modify the laser’s frequency and power to help the fragile qubits maintain their quantum state, thus ensuring the grid’s stability for more precise calculations and extended runtimes of the quantum machine. The research team also assessed how efficiently the lasers could shift qubits around within the array, as noted by Ellie Bataille at the California Institute of Technology.

“This is a remarkable demonstration of the straightforward scaling potential that neutral atoms present,” he remarks. Ben Bloom from Atom Computing also employs neutral atoms in their technologies.

Mark Suffman from the University of Wisconsin-Madison emphasizes that new experiments are vital, providing proof that neutral atomic quantum computers can achieve significant sizes. However, further experimental validation is necessary before considering these setups as fully developed quantum computers.

Research teams are currently investigating optimal methods for enabling qubits to perform calculations while employing error-reduction strategies, mentions Kon Leung at the California Institute of Technology. Ultimately, they envision scaling their systems to 1 million qubits over the next decade, he states.

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Source: www.newscientist.com

These Plants Exhibit Remarkable Mathematical Abilities

Can plants count from 1 to 10 using their root tendrils? No. However, researchers have discovered that some plants possess the fascinating ability to detect insect intruders and monitor their own food supply, allowing them to perform basic counting and mathematics.

Take, for instance, Venus flytraps, which are renowned for snapping shut when they detect movement from an insect or other triggers. Interestingly, this is only activated if the object moves twice within a time frame of approximately 15-20 seconds.

These movements are captured by delicate “trigger” hairs on the leaves, which convert the sensory input into electrical signals that travel through the plant as waves of charged atoms (ions). The leaves then close upon receiving two triggering electrical signals.

Additionally, a group of international scientists noted in a 2016 exhibition that Venus flytraps can tally multiple counts before reacting.

They wait to receive a minimum of three electrical signals before producing the necessary enzymes to digest their prey, potentially to avoid wasting energy on false alarms.

https://c02.purpledshub.com/uploads/sites/41/2025/09/Venus-fly-trap-vid.m4v
Venus flytraps pause to sense their prey’s movement before closing and secreting digestive juices.

Even prior to this finding, scientists had proposed that the mustard plant (Arabidopsis), a common research subject, exhibits behaviors akin to division.

During daylight hours, plants harness sunlight to accumulate food stores (starches) through photosynthesis.

To sustain themselves overnight, they must establish a balanced starch consumption rate (starch divided by time) by gauging the starch stored in their leaves alongside their circadian rhythms.

Experts caution against labeling these unique counting abilities as “intelligent” or indicative of a primitive brain structure; instead, they are vital survival mechanisms that demonstrate remarkable sophistication.


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New Hybrid Species of Blue and Green Jays Found in Texas

Hybridization among these species is notable within vertebrate groups. Such occurrences typically take place between recently diverged populations, with the most recent common ancestors of the Blue (Cyanocitta cristata) and Green (Cyanocorax yncas) Jays estimated to have existed at least 7 million years ago.



A hybrid of a man with a green Jay’s mother and a blue Jay’s father. Image credit: Brian R. Stokes.

“We’ve been working hard to engage with the community,” stated Brian Stokes, a graduate student at the University of Texas at Austin.

“While historical instances of vertebrate hybrids have often been linked to human influences—like the introduction of invasive species and recent range expansions—this particular case seems to have emerged due to climate shifts prompting the overlap of both parent species.”

During the 1950s, Green Jays, a tropical bird native to Central America, were limited to areas from Mexico to southern Texas, while Blue Jays, a temperate species found in the eastern U.S., extended westward to Houston, with minimal interaction between them.

However, their ranges have since converged around San Antonio as Green Jays migrated north and Blue Jays spread westward.

Stokes, who is focused on researching Green Jays in Texas as part of his PhD, actively monitors various social media platforms where birdwatchers share photos of sightings. This was one of several methods he utilized to capture birds, take genetic blood samples, and then release them back into their natural habitats.

One day, he spotted a rough image of an unusual blue bird featuring a black mask and white chest shared by a woman in the suburbs northeast of San Antonio. Although resembling a Blue Jay, it was distinctly different. The backyard birder welcomed Stokes for an in-person sighting.

“On our first attempt to capture it, the bird was quite elusive,” Stokes recounted.

“But the second day proved to be much more fortunate.”

Using a mist net—a long rectangular mesh of black nylon thread stretched between two poles, almost invisible to birds in flight—Stokes was able to successfully catch the bird on the second day after previously capturing and releasing dozens of others.

He quickly took a blood sample from this peculiar bird, allowing him to facilitate future research.

Interestingly, the bird vanished for several years, reappearing in the woman’s garden in June 2025. The reason for its return remains a mystery.

“I can’t explain it, but it felt like pure chance,” Stokes commented.

“Had it been two houses down, it likely wouldn’t have been reported at all.”

Investigations revealed that the bird is a hybrid descendant of a male Green Jay and a female Blue Jay.

It closely resembles other hybrids produced through researcher crossbreeding of Green and Blue Jays in the 1970s.

“Hybridization is likely far more prevalent in nature than researchers recognize, as we often miss these events happening,” Stokes expressed.

“Furthermore, in many species, physical barriers may prevent interactions that could lead to mating because we’re not actively observing.”

The team’s publication appears in the journal Ecology and Evolution.

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Brian R. Stokes and Timothy H. Keat. 2025. Intergenerational hybrids between historically isolated temperate and tropical Jays after recent expansion of the scope. Ecology and Evolution 15(9): E72148; doi: 10.1002/ECE3.72148

Source: www.sci.news

Research Shows Ice Dissolves Iron Minerals More Efficiently than Liquid Water

Ice at 10 degrees Celsius releases iron from more abundant minerals compared to liquid water at 4 degrees Celsius, according to researchers from Umeå University, Chimiques de Rennes, and CNRS. This discovery sheds light on why many Arctic rivers are taking on a rusty orange hue as permafrost begins to thaw in warmer climates.

Schematic diagram of the iron mineral dissolution reaction of ice. Image credit: Sebaaly et al. , doi: 10.1073/pnas.2507588122.

“It may seem counterintuitive, but ice is not merely a static frozen mass,” stated Professor Jean François Boyley from Umeå University.

“Frozen states create microscopic pockets of liquid water between ice crystals.”

“These pockets function like chemical reactors, where compounds become concentrated and highly acidic.”

“This implies that even at temperatures as low as 30 degrees Celsius, they can engage with iron minerals.”

To investigate this phenomenon, Professor Boyley and his team examined goethite, a diverse array of iron oxide minerals, along with naturally occurring organic acids.

Through advanced microscopy and a series of experiments, they found that repeated freeze-thaw cycles enhance iron dissolution significantly.

When ice undergoes freezing and thawing, it releases organic compounds that were previously trapped, fostering additional chemical reactions.

Salt concentration also plays a critical role; fresh brackish waters promote iron dissolution, whereas seawater inhibits it.

The outcomes of this research are particularly relevant in acidic environments like mine drainage sites, frozen atmospheric dust, acid sulfate soils along the Baltic coast, or acidic freezing locales where iron minerals interact with organic matter.

“As global temperatures rise, the freeze-thaw cycles are becoming more frequent,” remarked Angelo Pio Severly, a doctoral candidate at Umeå University.

“Each cycle liberates iron from the soil and permafrost into the water, potentially impacting water quality and aquatic ecosystems over vast areas.”

“These findings emphasize that ice is an active participant, rather than a passive medium for storage.”

“It is crucial to recognize the growing impact of freeze and thaw processes in polar and mountainous regions on ecosystems and elemental cycling.”

The research team’s paper was published on August 26, 2025, in the Proceedings of the National Academy of Sciences.

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Angelo P. Severly et al. 2025. Ice as a kinetic and mechanical driver for iron oxide dissolution of oxalate oxide. Proceedings of the National Academy of Sciences 122 (35): E2507588122; doi: 10.1073/pnas.2507588122

Source: www.sci.news

New Cretaceous Crocodile Species Discovered in Montana

Paleontologists have discovered a new species of extinct crocodile-like creature from fossilized remains found in southwest Montana, USA.



Impressions of the artist Thikarisuchus Xenodentes. Image credits: Dane Johnson/Rockies Museum.

The newly identified species existed at the edge of the ancient western inland sea around 95 million years ago, during the late Cretaceous period.

It has been named Thikarisuchus Xenodentes, a type of neostian.

“Measurements indicate it was less than 60 cm (2 feet) from nose to tail tip,” stated David Barilisio, a professor at Montana State University. “If it had grown fully, it could have reached about 90 cm (3 feet) or more, but still much smaller than most members of the Neosuchia clade to which it belongs.”

“This clade includes modern crocodiles and their closest extinct relatives, most of which are semi-aquatic or marine carnivorous animals with simple cone-shaped teeth.”

In contrast, Thikarisuchus Xenodentes likely lived on land and possibly fed on plants, insects, and small animals, possessing a variety of tooth shapes.

“Its unique anatomy indicates it is part of a newly identified family of crocodile-like creatures endemic to the Cretaceous in North America.”

The fossilized remains of Thikarisuchus Xenodentes—including its limbs, vertebrae, jaw, and a skull measuring 50 mm—were discovered in the US Forest Service Black Reef Formation near Dillon, Montana, in the summer of 2021.

“We previously found dinosaurs in the Black Reef Formation, making this the second known vertebrate species discovered in this layer,” remarked Harrison Allen, a doctoral student at Stony Brook University.

Paleontologists found the bones of Thikarisuchus Xenodentes in a densely packed arrangement consistent with the fossils of other living creatures found in the dens of the Black Reef Formation and nearby Wayan Formation in Idaho.

“This supports the idea that Thikarisuchus Xenodentes was preserved in dens and that fossils from these layers are biased toward those found in such environments,” they noted.

The specimen also suggested connections to a newly established family group, wannchampsidae, and a related group identified in Eurasia, known as the Atopasauriaceae.

Both families were small, globally adaptive, and exhibited specific skull and dental characteristics shared with more distantly related groups from the Cretaceous period in Africa and South America.

“We propose that shared environmental conditions and prey availability led to convergent evolution between these two distantly related groups during the same timeframe.

“The vast majority of alligatorid diversity belongs to the past, including fully marine crocodiles, entirely terrestrial crocodiles, herbivorous, omnivorous species, and those with unique shells.”

“This discovery surprised me and motivated my interest in this specific field of paleontology.”

A paper detailing the findings is published in the Journal of Vertebrate Paleontology.

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Harrison Allen et al. 2025. The impact of newly discovered small heterodonneostians and heterodonneostians in southwestern Montana’s Black Leaf Formation on paleoecology. Journal of Vertebrate Paleontology in press; doi: 10.1080/02724634.025.2542185

Source: www.sci.news

New Research Confirms Multiple Instances of Water Activity in Jezero Crater

Minerals constitute the building blocks of rocks, and the specific minerals and their chemical compositions reveal significant insights into rock formation and history. On Mars, NASA’s dedicated rover, equipped with X-ray lithochemistry (PIXL) instruments, produces geochemical maps of rock surfaces. A recent study examined over 90,000 chemical analyses collected by PIXL during its first 1,100 days on Mars, revealing that the minerals in Jezero Crater interact with various types of liquids over time. result This will be published in Journal of Geophysics: Planets.

This image from NASA’s Mars reconnaissance orbiter showcases the Jezero Crater on Mars. Image credits: NASA/JPL-CALTECH/MSSS/JHU-APL.

In this research, Eleanor Moreland, a Rice University graduate student, along with her team, utilized mineral identification through stoichiometry (MIST) algorithms to analyze PIXL data.

PIXL determines the chemical composition by bombarding Martian rocks with X-rays, yielding the most comprehensive geochemical measurements ever obtained from another planet.

“The minerals identified in Jezero Crater through MIST indicate that these volcanic rocks interacted with liquid water multiple times throughout Mars’ history, suggesting the potential for habitable conditions,” Moreland stated.

Minerals form under specific environmental conditions, such as temperature, pH, and the chemical composition of fluids, making them reliable narrators of planetary history.

Within Jezero Crater, 24 mineral species illustrate the volcanic characteristics of the Martian surface and their interactions with water over time.

Water chemically alters rocks, producing salt or clay minerals, with the specific minerals formed depending on environmental variables.

The minerals discovered in the crater showcase three different types of liquid interactions, each indicating distinct possibilities for habitability.

The first mineral suite, featuring green arilite, hizingerite, and ferroaluminoceradonite, shows localized high-temperature acidic fluids present only in crater bedrock, interpreted as among the oldest rocks studied.

The water involved in this scenario is regarded as the most conducive to life, given that research on Earth suggests high temperatures and low pH can harm biological structures.

“These hot, acidic conditions present the toughest challenges to life,” commented Kirsten Siebach, a researcher at Rice University.

“However, on Earth, life can thrive in extreme environments such as the acidic waters of Yellowstone, so this doesn’t negate the possibility of habitability.”

The second mineral suite favors more hospitable conditions and indicates a medium neutral fluid present over larger areas.

Minerals like Minnesotaite and Clinoptilolite were detected on both the crater floor and fan area, forming at lower temperatures with neutral pH, while Clinoptilolite was restricted to the crater floor.

Lastly, the third category represents a cold alkaline liquid, considered highly habitable from a modern Earth perspective.

Sepiolite, a common mineral change on Earth, was found to form under moderate temperature and alkaline conditions, widely distributed across all units explored by the rover.

The presence of sepiolite in all these units indicates multiple episodes of liquid water contributing to habitable conditions in Jezero Crater.

“These minerals demonstrate that Jezero Crater has undergone a transition from harsher, hotter, acidic liquid conditions to more neutral and alkaline environments over time.

Given that Mars samples cannot be prepared or scanned as accurately as Earth samples, the team developed an uncertainty propagation model to enhance the findings.

Using a statistical approach, MIST repeatedly assessed mineral identification while considering potential errors, analogous to how meteorologists predict hurricane paths by utilizing numerous models.

“Error analysis enables us to assign confidence levels to all mineral identifications,” Moreland remarked.

“MIST assists not just with the scientific and decision-making processes of Mars 2020, but also establishes a mineralogical archive of Jezero Crater, which will be invaluable if samples are returned to Earth.”

The findings affirm that Jezero Crater, once home to an ancient lake, has experienced a complex, dynamic aqueous history.

Each new mineral discovery brings us closer to determining whether Mars has ever supported life, while also refining strategies for sample collection and return.

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Eleanor L. Moreland et al. 2025. Multiple episodes of fluid changes in Jezero Crater indicated by the identification of MIST minerals in PIXL XRF data from the first 1100 SOL of the Mars 2020 mission. Journal of Geophysics: Planets 130 (9): e2024je008797; doi: 10.1029/2024je008797

Source: www.sci.news

Discovery of a New Carnivorous Dinosaur Species in Argentina

A recently identified member of the Megaraptran dinosaur family has been unveiled by a collaborative effort of Argentine and US paleontologists.



Joaquinraptor Casali. Image credit: Andrew McCuffy, Carnegie Museum of Natural History.

This newly discovered dinosaur species inhabited Patagonia, Argentina, during the later stages of the Cretaceous period, approximately 70 to 67 million years ago.

Dubbed Joaquinraptor Casali, these ancient predators were the apex carnivores in the region.

It is a member of the Megaraputra, a lineage of large, clawed carnivorous theropod dinosaurs recognized from Cretaceous deposits across Asia, Australia, and especially South America.

“Megaraptrands were carnivorous theropods characterized by elongated skulls, large claws, and robust forelimbs found in Asia, Australia, and South America,” stated Dr. Lucio Ibilik, a paleontologist at Patagonico de Geología y Paleontología.

“Nevertheless, our comprehension of this group is limited due to the scarcity of complete fossils.”

A well-preserved, partially articulated skeleton of a single Joaquinraptor Casali specimen was uncovered in the Lago Corfue Huapi Formation, situated in the South Central Chubut province of central Patagonia, Argentina.

The specimen comprised numerous dinosaur skulls, anterior limbs, hind legs, ribs, and vertebrae.

Based on the microstructure of the bones, paleontologists propose that the specimen is an adult, albeit possibly not fully matured.

Drawing from other megaraptran remains, they estimate that Joaquinraptor Casali measured about 7 meters in length and weighed over 1,000 kg.

Evidence from sediment suggests this dinosaur thrived in a warm, humid floodplain environment.

“The discovery of bones within the fossilized remains of a crocodilian’s leg pressed against the lower jaw of Joaquinraptor Casali provides insights into its feeding habits, suggesting it may have been a primary predator in its habitat,” the researchers noted.

“However, additional studies are necessary to enhance our understanding of its behavior and ecological role.”

According to scientists, Joaquinraptor Casali and other factions of Megaraputra remained dominant predators in this area of South America, ultimately facing extinction alongside other non-avian dinosaurs at the end of the Cretaceous period.

“It seems that South American megaraptolids achieved larger body sizes (over 7 m in length) than their generally smaller counterparts in Australia (5-6 m),” they added.

“The Patagonian Megaraputrids may have continued to grow throughout their evolutionary history, possibly influenced by the extinction of Carcharodontosaurus during the late Cretaceous.”

“Furthermore, this could have permitted Megaraptorids to fill a niche as apex predators within their ecosystems.”

“Moreover, as suggested by the stratigraphy of the Maastrichtian (likely late Maastrichtian), Joaquinraptor Casali may have survived until the Cretaceous-Paleogene boundary, perishing alongside all other non-avian dinosaurs.”

The discovery of Joaquinraptor Casali has been detailed in a paper published in the journal Nature Communications.

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lm ibiricu et al. 2025. The latest Cretaceous Megaraptolid Cellopod dinosaurs shed light on the evolution and paleontology of megaraptrans. Nut commune 16, 8298; doi:10.1038/s41467-025-63793-5

Source: www.sci.news

Is Leucovorin an Effective Treatment for Autism? Insights from Recent Research

The Trump administration has included a drug known as leucovorin in efforts to alleviate certain autism symptoms. However, experts specializing in autism largely agree that additional research is needed before it can be widely used in children and adults.

Leucovorin, or Folinic Acid, is a synthetic variant of vitamin B9 requiring a prescription. It is primarily administered to cancer patients via IV alongside chemotherapy.

On Monday, the Food and Drug Administration revealed that it is moving forward with the approval of a tablet formulation for specific autistic patients.

Many researchers have raised concerns that this approval may be hasty, given that only a few small trials—mostly conducted outside the US—demonstrate its effectiveness in children with autism.

Several experts informed NBC News that FDA approval might create unrealistic expectations for families. This is particularly concerning as not all children with autism are eligible for prescriptions, and the likelihood of achieving positive results remains uncertain.

Researchers have long sought medications that can effectively mitigate autism symptoms; however, very few have satisfied the FDA’s rigorous safety and efficacy criteria. Prior to Monday, the FDA had only authorized two medications to address bothersome symptoms associated with autism, none of which targeted issues related to communication, social interactions, or repetitive behaviors.

Alycia Halladay, Chief Science Officer of the Autism Science Foundation, commented that her organization supports research grounded in evidence; leucovorin is not suggested as a treatment and more research is essential.

“Leucovorin doesn’t meet the standards set for FDA approvals, yet this administration is proceeding regardless. Therefore, I wouldn’t label this a victory,” Halladay remarked.

She further noted that the way the drug was presented at Monday’s White House Briefing as a major breakthrough for families with autism doesn’t align with the nuances of FDA approval.

The FDA stated in a news release that the drug is being approved for patients suffering from cerebral folate deficiency, a rare neurological disorder marked by low levels of vitamin B9 (folate) in the brain. Some researchers speculate that this condition might be linked to autism, but it is not present in all autistic individuals.

(Halladay estimates that around 10-30% of autistic patients may have this condition.)

Though leucovorin can potentially aid in reaching the brain, theoretically improving verbal communication and alleviating autism symptoms like irritability and repetitive actions, there is no evidence to suggest it entirely eradicates these symptoms.

“We still hope that leucovorin might serve as a helpful option for a subset of patients,” noted Dr. Rachel Forlomer, an assistant professor of pediatrics at Northwestern University’s Feinberg School of Medicine. “However, I can’t say we’re at a stage where we can confidently claim we can assist every individual with autism.”

President Donald Trump expressed at a briefing that the approval “offers hope for many parents of children with autism that life improvement is possible.” Mehmet Oz, leader of the Centers for Medicare and Medicaid Services, described the decision as “life-saving.” FDA commissioner Marty McCurry remarked, “I believe hundreds of thousands of children will benefit.”

However, in a follow-up news release, the Department of Health and Human Services clarified that leucovorin is “not a cure” for autism and “may only result in improvements in speech-related deficits for a subset of children.”

David Mandel, a professor of psychiatry at the University of Pennsylvania, remarked that the folate hypothesis is based on relatively weak scientific evidence.

“We lack robust large-scale studies demonstrating that a significant number of individuals with autism suffer from folic acid deficiency,” he noted.

While leucovorin has shown minimal side effects in cancer patients, higher doses can lead to gastrointestinal issues and increase the risk of seizures in individuals on anti-seizure medications. It is commonly part of treatment for colorectal cancer and other gastrointestinal malignancies, often enhancing the efficacy of the chemotherapy drug 5-fluorouracil. In rare cases, it is administered to reduce side effects from another chemotherapeutic agent, high-dose methotrexate.

Halladay mentioned observing side effects during the leucovorin autism trial but noted that the specific safety of the drug was not evaluated. She indicated that dosages varied across studies, making it difficult to determine if leucovorin was responsible for any symptom improvement, as some trial participants also received behavioral therapy.

According to Mandel, the largest study involving these trials included only 80 participants.

“For FDA approval, one would ideally want hundreds of children involved in these trials,” he explained.

Leucovorin must overcome one final obstacle before it becomes available to select autistic patients. The FDA stated it is collaborating with GSK, the manufacturer of the brand-name version of leucovorin, to update the drug’s labeling. GSK confirmed that a new application will be submitted to include autism indications.

Oz stated on Monday that leucovorin prescriptions will be covered by Medicaid, with private insurance companies likely to follow suit.

However, Mandel expressed concern that anticipated cuts to Medicaid may compel many families to cover costs out of pocket, potentially driving them to purchase folinic acid supplements online without prescriptions. Such supplements may not have gone through quality control, and dosage information could be unclear.

Dr. William Dahoot, chief science officer at the American Cancer Society, expressed concern that the growing interest in leucovorin for autism might adversely impact its availability for cancer patients.

“We have faced shortages of this drug before, and an increase in demand could lead to future shortages,” he noted in an email.

Source: www.nbcnews.com

Clues to Exotic Dark Matter Particles Could Be Found in LHC Data

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ATLAS Detector of the Large Hadron Collider

Xenotar/Getty Images

The theoretical particles known as axions have attracted the attention of physicists for decades, as they are significant candidates for identifying dark matter. Recent research suggests that we might not need new experiments to discover these exotic particles; evidence could already be embedded in existing data from previous particle collider experiments.

Particle colliders like the Large Hadron Collider (LHC), located at CERN near Geneva, Switzerland, discover new particles by colliding protons and ions, analyzing the resulting debris. Now, Gustabo Gilda Silveyra and his team at CERN are exploring another avenue: can we detect when a proton or ion emits a new particle during acceleration? Their findings indicate that this may indeed be possible.

The axion was theorized in the 1970s as part of a pivotal solution to a significant problem in physics. Its importance surpasses even that of antimatter. Although the ongoing search for experimental evidence of axions has not yet yielded results, it raises the possibility that other particles resembling axions might exist. Due to their incredibly low mass, they bear a close resemblance to substantial quantities of light or photons, interacting together with the LHC.

This interaction primarily occurs when protons or ions are accelerated to astonishing energy levels. As these particles approach each other, they begin to emit radiation in the form of photons, which may then collide with one another. Researchers have modeled this scenario, replacing photons with axion-like particles. Their results indicate that accelerated protons exhibit a higher likelihood of generating axion-like particles compared to accelerated ions, with both producing photons simultaneously. Consequently, the team has identified collisions between protons and lead ions as optimal for uncovering signals related to axions influencing photons. The specific proton-lead ion collisions were executed at the LHC in 2016, and the researchers propose that data from these experiments might have been previously overlooked but could contain vital hints about new axion-like particles.

Lucien Haaland Lang from University College London has remarked that this approach presents an intriguing new pathway to uncover potential undiscovered particles, though he cautions about the challenges involved. “Such collision events are rare, and we must be cautious to differentiate our findings from background processes that may inadvertently mimic the signals we seek,” he notes.

Access to older LHC data poses challenges due to updates in software, according to Da Silveira. However, he expresses optimism regarding future experiments at the LHC. “We will be able to adjust the detector to capture this specific signal,” he states.

Identifying a particle signal analogous to an axion does not equate to discovering an actual axion, thus leaving one of the major unresolved questions in physics unanswered. Nonetheless, it expands our understanding of particle physics, prompting inquiries into how new particles might interact with known counterparts and whether they might help explain the enigmatic dark matter that permeates the universe.

Journal Reference: Physical Review Letter, In print

Topics:

  • Large Hadron Collider/
  • Particle Physics

Source: www.newscientist.com

What We Know and Don’t Know About the Connection Between Painkillers and Autism

The US government raised concerns about painkillers used during pregnancy

Solstock/Getty Images

On Monday, the US government introduced two initiatives concerning autism. One update involves labeling for paracetamol, commonly known as acetaminophen, emphasizing that its use during pregnancy could elevate the risks of autism and ADHD in children. The government also approved leucovorin for certain children diagnosed with autism spectrum disorder (ASD). However, these actions are not strongly supported by scientific evidence and may have negligible effects on autism prevalence in the United States.

This announcement followed Robert F. Kennedy Jr.’s pledge, made in April, to uncover the causes of autism by the close of September. President Donald Trump later described this initiative at a press conference as “a historic step towards battling the autism crisis.”

This portrayal indicates a possible misunderstanding or distortion of existing knowledge about autism. There is no crisis as such. Autism rates began to surge rapidly since the 1980s, significantly influenced by increased awareness and recognition of its symptoms leading to more frequent diagnoses.

Evidence supporting the idea that paracetamol causes autism is limited. While several studies indicate a correlation between paracetamol use during pregnancy and an elevated risk of autism in children, causation should not be assumed. A recent investigation involving 46 studies found that 27 of them reported a significant link between paracetamol use in pregnancy and heightened risk for neurodevelopmental issues, including autism. Nevertheless, correlation does not imply causation; other underlying factors may also play a role.

Contrasting findings are evident in other studies. For instance, a 2024 evaluation analyzing around 2.5 million children determined that while those exposed to paracetamol during pregnancy faced a marginally higher autism risk, this effect diminished when comparing children exposed to painkillers with their siblings. “It wasn’t the paracetamol use, but rather family history that played a crucial role,” said Dimitrios Siasacos from University College London. “Although studies indicate a slight increase in autism outcomes related to paracetamol use during pregnancy, this tends to vanish when analyzing the more significant factors involved.”

During a press briefing, Trump advised that pregnant women should avoid taking paracetamol for pain or fever. However, the US Food and Drug Administration (FDA) issued a press release stating that no causal link between paracetamol and autism has been established. Additionally, in a notification to healthcare providers, the FDA confirmed that paracetamol remains the safest and most accessible pain relief option during pregnancy. “[It] is the only over-the-counter medication that is approved for use to treat fever during pregnancy, as a high fever can pose risks to the developing fetus,” emphasizing potential fetal brain or spinal cord defects.

The FDA also announced its approval of leucovorin for individuals with cerebral folate deficiency, a condition that affects the brain’s capability to absorb vitamin B9. Studies suggest that around 40% of people with autism may be affected by this deficiency, leading to similar symptoms, including difficulties with communication and sensory processing.

Leucovorin, a form of vitamin B9, is already utilized to address deficiencies of this vitamin and to mitigate side effects from certain cancer treatments. Preliminary evidence implies that it might aid in alleviating severe autism symptoms. For instance, a 2016 study involving 25 autistic children treated with leucovorin demonstrated that 65% showed meaningful improvements in verbal communication skills compared to only 24% in the placebo group after 12 weeks.

However, existing studies on leucovorin and autism have been relatively small, often yielding only modest positive results. Larger clinical trials are in progress, with results expected next year. “Currently available evidence is tentative and not yet deemed comprehensive,” stated Monique Botha at Durham University. “While these medications might offer benefits in specific areas, there are no treatments that effectively address or eliminate autism as a whole.”

Following the announcement, the U.S. Department of Health and Human Services reiterated that “while promising, it’s crucial to understand that leucovorin is not a cure for ASD but may help to enhance speech-related skills in a limited group of children with the condition.”

With Trump’s backing, Kennedy is positioning the “autism epidemic” as a cornerstone of U.S. public health policy. They are both framing these policy developments as substantial milestones achieved in a brief timeframe. However, scientific evidence suggests that avoiding paracetamol during pregnancy or utilizing leucovorin is unlikely to have the significant impact on autism that Trump and Kennedy claim. Instead, the most probable outcome of these initiatives pertains to how and when to manage pain and fever safely during pregnancy.

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Source: www.newscientist.com

Brain Structure Mapping Alone Fails to Capture Its Functionality

The human brain contains trillions of connections

Sherbrooke Connectivity Imaging Lab/Connect Images/Alamy

Is it possible to fully comprehend brain function if we can accurately map its structures? Researchers aim to develop a wiring diagram, or connectome, of our neural pathways, yet the task of unveiling the brain’s mysteries is proving to be complex.

The Connectome serves as a roadmap for nerve signal pathways, but Sophie Dovari from Princeton University and her team have found notable gaps in these pathways.

Researchers analyzed the connectome of the nematode worm, Caenorhabditis elegans, and compared it to recorded neural signals. They accomplished this by stimulating each neuron and observing how signals flowed through the connectome. This method is feasible with nematodes due to their relatively simple nervous system, composed of roughly 300 neurons.

Nematode worms are significantly simpler than humans, with approximately 300 neurons depicted in green

Heiti Paves / Alamy Stock Photo

By viewing these two datasets as mathematical networks, researchers can ascertain whether closely connected groups of neurons manifest a high frequency of signal exchanges. They uncovered that this correlation is not always evident.

Dvali notes instances of substantial connection density and overlapping signal exchanges, like how worms eat or the groups of neurons that correspond well. However, even in cases where they appeared significantly connected, a gap remained in understanding their respective functionalities across both networks. Overall, these findings suggest that the biological connectome is insufficient to predict all neural behaviors.

Team member Andrew Leifer, also from Princeton University, points out that signals do not always follow the shortest paths between neurons; some may communicate beyond their direct connections. “While we typically leverage connectomes for research, the multitude of useful connections calls for deeper comprehension,” he explains.

According to Albert Laslo Barabasi at Northeastern University, Massachusetts, criticism surrounding connectomics often revolves around its inability to provide action-oriented insights from structural data. This new paper seeks to address that challenge.

Looking forward, researchers aim to delve deeper into how signals disseminate through the connectome when multiple neurons are activated simultaneously, with aspirations to study more complex organisms, such as fruit fly larvae, recognized for their intricate neural networks. “We are on the verge of a revolution in brain mapping,” Barabasi concludes.

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Source: www.newscientist.com

New Species of Dinosaur Discovered Within Crocodile Jaw

Reconstruction of the artist’s dinosaur Joaquinraptor Casali

Andrew McAfee, Carnegie Museum of Natural History

During the Cretaceous period, South America was a site of significant dinosaur discoveries.

Named the dinosaur species Joaquinraptor Casali, this megaraptor was uncovered in 2019 along the banks of the Liochico River in Patagonia, Argentina. It is believed to have existed just before the mass extinction of non-avian dinosaurs 66 million years ago.

Recently, Lucio Ibiricu from the National Council on Science and Technology Research in Tubat, Argentina, and his team conducted an in-depth analysis of the fossil, revealing unexpected findings in the nearly complete skull.

“A relative humerus, likely belonging to an extinct crocodile, was found between the jaws of Joaquinraptor and was in direct contact with its teeth,” states Ibiricu. “This indicates a unique ecological interaction at the time of death.”

Further investigations of the crocodilian humerus are ongoing to ascertain its size, but initial assessments suggest it is considerable, according to Ibiricu.

In addition to the recovered skull, the excavation yielded vertebrae, feet, two claws, arms, legs, and hands. Notably, the thumb claw—approximately the size of a human forearm—could have been effective for tearing the flesh of its prey, according to Ibiricu.

Fossils of other megaraptors have been discovered across Asia, Australia, and South America. Joaquinraptor was first identified close to the Cretaceous period’s end, and it is among the more complete specimens found.

The thumb claw of the dinosaur

Matt Lamanna

The scientific team concluded that the dinosaur was at least 19 years old at the time of its demise, based on the microstructure of the tibia. It measured approximately 7 meters in length and weighed a minimum of 1 tonne.

Meanwhile, Tyrannosaurus Rex was considerably larger and boasted a massive head, as noted by Ibiricu. Nonetheless, he emphasizes that both species represented apex predators within their respective environments.

Dinosaur Hunting in the Gobi Desert, Mongolia

Experience an exciting and unique expedition that explores the renowned sites of dinosaurs in the vast expanse of the Gobi Desert, a premier paleontological hotspot.

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Source: www.newscientist.com

The Mystery of Earth’s Ancient Frozen Nuclei Unveiled: Discovering the Reasons Behind Their Existence

We may finally understand what caused the inner core of the Earth to freeze.

The inner core is a sphere of iron approximately 2,400 km (1,500 miles) in diameter, enveloped by a molten outer core. Its growth is responsible for generating the Earth’s magnetic field, which shields the planet from harmful solar radiation. However, the precise process by which the core first crystallized has remained unclear.

Recent research published in Nature Communications suggests a mechanism that hinges on deep Earth chemistry. By utilizing advanced computer simulations, scientists examined how various factors influence the freezing of iron under extreme pressure and temperature at the planet’s center.

They found that incorporating carbon allows iron to solidify under realistic conditions, positioning it as a key component in understanding the ingredients that contributed to the formation of the inner core billions of years ago.

“By investigating how Earth’s inner core formed, we gain insights not only into the planet’s history,” said Dr. Alfred Wilson from the University of Leeds, who led the study.

“We get rare insights into the chemistry of a region that we can never physically reach, and we can only speculate on how it might change in the future.”

The inner core lies deep within the planet, beneath layers of rock and magma – Credit: Getty Images/EPS Vector

At the extreme pressures found 5,000 km beneath our feet, iron doesn’t simply freeze when it drops below its melting point; it requires “super-cooling” of the crystals before they form. Pure iron must be cooled to as low as 1,000°C (1832°F), resulting in a significantly larger core than the one we see today.

New computer modeling indicates that the presence of carbon alters this equation. With less than 4% carbon in the mix, iron can crystallize at much lower temperatures, producing a core that aligns with seismic observations.

Scientists believe that the Earth’s center likely continues to host a mixture of elements. However, this research firmly highlights the critical role of carbon in one of geology’s greatest mysteries.

Read more:

Source: www.sciencefocus.com

Optimizing Your Cortisol Rhythm: How to Make It Your New Normal

Feeling exhausted? Has bloating become a concern? Are sleepless nights troubling you? Your cortisol levels might be elevated – at least that’s the prevailing notion on social media.

Cortisol has recently garnered attention from various health and wellness influencers, who attribute all sorts of issues to it. Fortunately, this is a challenge that can often be addressed with the right blend of supplements.

But what is cortisol exactly? And why has it become a source of so much concern?

Cortisol is widely recognized as a stress hormone. When faced with a potential danger, the amygdala in your brain activates a “fight or flight” mechanism. This leads to the release of adrenaline and noradrenaline, preparing your body to either confront or flee from the threat. You might feel this rush when startled by a scary movie or while feeling anxious before a big presentation.

In most instances, stress is temporary – fear is immediate, and presentations are often short-lived – allowing our adrenaline levels to stabilize shortly afterward. Neuroscientists and psychologists refer to this as acute stress, which in moderation can actually be beneficial for us.

Cortisol comes into play when stress is prolonged or perceived as unmanageable. In these situations, cortisol is secreted from the adrenal glands situated above the kidneys.

This release peaks after about 15-20 minutes, during which it helps the body sustain its response to threats by ensuring energy availability, maintaining blood flow to muscles, and keeping the brain alert.

However, this isn’t the case for every instance of fear or stress. “It’s quite difficult to trigger a cortisol response from acute stress,” says Professor Stafford Reitman from the University of Bristol School of Medicine.

“While it’s easy to evoke an adrenaline response, initiating cortisol release is more complex, as it depends on how you personally perceive a situation as a genuine threat.”

A 2025 study involving 201 healthy volunteers found that cortisol levels peaked just before waking.

Nonetheless, cortisol’s role extends beyond stress responses. It has several essential functions, some of which are beneficial. For instance, cortisol plays a crucial role in helping you rise in the morning: your cortisol levels increase before you wake up. Without this morning boost, getting out of bed would be even more challenging.

Cortisol is involved in various functions, as Reitman notes. “Cortisol acts as a signaling molecule. Almost every tissue in the body possesses cortisol receptors, found in the muscles, liver, and brain.”

When organs and muscles receive cortisol signals, they trigger vital processes that stabilize the body. For example, when organs like the liver or pancreas detect cortisol, they help maintain stable blood sugar levels and consistent blood pressure. Additionally, cortisol can initiate anti-inflammatory responses within the body, providing short bursts of immune system support.

“Cortisol performs multiple tasks,” Lightman explains. “Its regulation is critically important, as it’s the only hormone essential for life – without cortisol, survival is impossible.”

Understanding Patterns

Clearly, some cortisol is necessary, but what if you’re concerned about having too much?

This can be tricky to assess because cortisol levels naturally fluctuate throughout the day (rising in the morning and declining by evening). The challenge is that home test kits used for measuring cortisol typically capture a single snapshot each day, labeling levels as “high” or “low.”

Lightman describes these tests as “utterly inadequate,” noting that “normal fluctuations can vary widely at any given moment, making it difficult to determine whether someone’s cortisol level is truly high or low. Levels could differ completely just 20 minutes later.”

For an accurate assessment, you’ll need to track cortisol over several days. This is how healthcare professionals diagnose conditions related to cortisol release abnormalities.

Moreover, cortisol tends to be released in bursts approximately every hour. This release pattern influences gene activity and is critical for numerous bodily functions. One study investigating this involved healthy volunteers undergoing cortisol suppression, then receiving matching doses that either mimicked a non-pulsed daily (circadian) pattern or a pulsatile circadian rhythm (akin to natural cortisol release).

Participants following the non-pulsed protocol exhibited declines in working memory tasks and sleep quality. However, those in the pulsed protocol were less adept at identifying facial expressions linked to improved mental health compared to their counterparts. The findings suggest that the release pattern may be crucial for functionality rather than merely the cortisol amount present.

Research involving mice indicates that higher cortisol levels may facilitate neuronal connections, aiding in more effective skill acquisition. However, adequate cortisol levels are imperative for learning new skills. These connections are retained in the brain for extended periods.

Even if continuous tracking of cortisol were possible, it wouldn’t necessarily inform your health status. “You first need to establish what’s considered normal for an individual,” Reitman emphasizes. “Then it becomes evident if their daily pattern deviates from that norm. No one has performed this assessment. Claims of ‘dysregulated patterns’ are misleading,” he asserts.

Incorporating the Japanese practice of “Shinrin Yoku” or forest bathing has consistently been shown to lower cortisol levels – Getty

Stay Calm

Scientists concur that chronic stress can negatively impact our health, and managing it can improve our quality of life. However, Reitman advises against hastily attributing health issues to cortisol.

“Experiencing long-term stress from events like divorce, job loss, or restless nights can lead to health problems, but this doesn’t necessarily mean cortisol is the culprit.”

Addressing the underlying causes of stress is often the most effective treatment, rather than relying on supplements to reduce cortisol levels, although this may not always be viable.

Fortunately, there are various strategies available for managing stress. For instance, a 2019 survey revealed that older adults who engaged in three months of dance training experienced lower peak cortisol levels. Dance has also been shown to reduce stress.

Additionally, physical affection can be effective in managing immediate stress levels. One study indicated that students receiving more hugs than usual experienced lower morning cortisol spikes the following day.

Spending time in nature, such as walking through forests, has also proven beneficial. One study found that forest bathing can reduce cortisol levels by 53%.

Unless you’re a villain, cortisol is crucial for our body and brain; for most of us, worrying about it is hardly necessary.

It’s best to steer clear of influencers selling the latest health trends and focus instead on the fundamentals of healthy living (diet, exercise, sleep) – especially when true joy can often be found in the real world.

Read more

Source: www.sciencefocus.com

Hubble Space Telescope Reveals Stunning New Images of NGC 2775

The prominent, yellowish bulge at the core of NGC 2775 is populated with older stars, encircled by tightly wound spiral arms adorned with areas of dark dust and young blue stars.



This Hubble image captures NGC 2775, a galaxy located approximately 67 million light years away in the Cancer constellation. Image credits: NASA/ESA/Hubble/F. Belfiore/J. Lee/Phangs-HST team.

NGC 2775 is situated about 67 million light years from the northern constellation of Cancer.

This galaxy was discovered on December 19, 1783, by British astronomer William Herschel, who was originally from Germany.

NGC 2775 is a principal member of the Galaxy’s Anti-Rahydra Cloud and part of a small group of galaxies known as the NGC 2775 group.

Also referred to as Caldwell 48, Leda 25861, or UGC 4820, NGC 2775 has a diameter of approximately 80,000 light years.

“NGC 2775 has an unusually smooth center that is devoid of gases, resembling an elliptical galaxy,” noted Hubble astronomers in a statement.

“It contains dusty rings with clusters of patchy stars, similar to spiral galaxies.

“Observing NGC 2775 from a single perspective makes it challenging to ascertain its true nature.”

“While some researchers classify NGC 2775 as a spiral galaxy due to its star and dust patterns resembling feathered rings, others categorize it as a lenticular galaxy.”

“Lenticular galaxies exhibit characteristics of both spiral and elliptical types.”

“The exact appearance of a lenticular galaxy remains uncertain, as they can form in various ways.”

“Some lenticular galaxies may have originated as spiral galaxies that fused with one another or may have lost their star-forming gas and prominent spiral arms.”

“They might also have accumulated gas in their surrounding discs, leading them to appear more oval-shaped.”

Astronomers suggest that NGC 2775 may have merged with other galaxies in the past.

“In the Hubble image, NGC 2775 features a hydrogen gas tail extending nearly 100,000 light years around the galaxy,” the researchers indicated.

“This faint tail could represent the remnants of one or more galaxies that ventured too close to NGC 2775 before being absorbed.”

“If NGC 2775 has indeed merged with other galaxies previously, it could help to explain the unusual appearance of the galaxy as we observe it today.”

“Hubble’s images of NGC 2775 were released earlier in 2020,” they added.

“The updated version includes observations of specific wavelengths of red light emitted by hydrogen gas clouds surrounding the young giant star.”

Source: www.sci.news

Fossils from the Oligocene Cycle Reveal Pollination Interactions Between Flowers and Marchalace

Paleontologists have examined fossilized flowers and bees dating back 24 million years, following the scarcity in Enspel, Germany, and unveiled new species of Linden. These include Tilia Magna Separa and two newly identified bumblebee species, Bombos (Chrono Bombos) Mesegas and Timebombus Palaeocrater. The presence of identical tyria pollen in both the flowers and on the outer surfaces of the bumblebees serves as direct evidence of their interactions, identifying Bombos as a pollinator of Tyria. At least due to the late decline, we remain anchored in the present.

Tilia Magna Separa. Image credit: Christian Geier.

“We analyzed countless fossil flowers and insect pollens in hopes of understanding the evolution of flowers, their visitors, and the pollination process,” stated Dr. Friðgeir Grímsson, a researcher at the University of Vienna.

“These microscopic pollen grains were made visible using UV and blue light, and then extracted individually from flower or insect hair, or aggregated from insects, with the aid of extremely thin needles and minimal invasive techniques.”

The pollen grains underwent careful washing and were analyzed using high-resolution light and electron microscopes.

Many of the flowers studied originated from Linden trees, with numerous bumblebees visiting Linden flowers prior to their fossilization in an ancient volcanic crater lake.

“The newly identified linden flower has been named Tilia Magna Separa,” said Christian Geier, a doctoral student at the University of Vienna.

“Additionally, two new bumblebee species have been identified: Bombos (Chrono Bombos) Mesegas and Bombos (Time Bombos) Pereoctor.”

The fossils were uncovered during the excavation of lake sediments from the former volcanic lake near Enspel in Rhineland-Palatinate, Germany.

Tilia Magna Separa marks the first recorded flowers from the European continent, characterized and described as per pollenological standards—the science of pollen,” the researchers noted.

“The fossil bumblebees rank among the oldest representatives of their genus, with only one species from Colorado, USA, predating them.”

“This is the first instance globally where a fossil flower and its pollinator bee have been described arising from the same deposits, with pollen linking them directly,” Geier remarked.

“Such research holds significant potential to enhance our understanding of past pollinator dynamics.”

The Fossil Record offers insights into the evolutionary developments of the past, revealing changes due to climate shifts, species extinction, and evolutionary adaptation.

By analyzing fossilized animal and plant groups, we can infer their behaviors and reactions to environmental changes.

“Our research allowed us to identify specific flower homeostasis among the bumblebees studied,” Geier explained.

“This indicates that they tend to visit only one type of plant during a single flight.”

“These findings are crucial for gaining a deeper understanding of the delicate interactions and resilience within today’s ecosystems.”

The study was published today in the journal New Botanist.

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Christian Gayer et al. 24 million years of pollination interaction between European linden flowers and bumble bees. New Botanist, published online on September 22, 2025. doi: 10.1111/nph.7053

Source: www.sci.news

Astronomers Uncover the Most Distant Black Hole Ever Detected

A newly identified supermassive black hole resides in the center of the “Little Red Dot” galaxy, known as Capers-LRD-Z9, existing merely 500 million years after the Big Bang.



Artistic impressions of Capers-Lrd-Z9. Image credit: Erik Zumalt, University of Texas, Austin.

“Finding a black hole like this pushes the limits of what we can currently detect,” remarked Dr. Anthony Taylor, a postdoctoral researcher at the University of Texas at Austin.

“We’re truly expanding the boundaries of technological capability today.”

“While astronomers have identified more distant candidates, clear spectroscopic signatures for black holes have yet to be found,” noted Dr. Stephen Finkelstein from the University of Texas at Austin.

The astronomers conducted their research using data from the NASA/ESA/CSA James Webb Space Telescope, as part of the CAPERS (Candels-Area Prism Epoch of Reionization Survey) program.

Initially regarded as a mere speck in the program images, Capers-LRD-Z9 is now recognized as part of a newly classified category of galaxies called Little Red Dots.

“The find of the Little Red Dot was a surprising revelation from initial Webb data. It did not resemble the galaxies captured by the NASA/ESA Hubble Space Telescope,” Dr. Finkelstein explained.

“We are currently working to understand what they are and how they formed.”

Capers-Lrd-Z9 contributes to the growing evidence that the ultra-large black hole plays a critical role in the unusual luminosity of small red dots.

Typically, such brightness signifies a galaxy teeming with stars. However, in the absence of substantial stellar mass, these small red dots cease to exist.

These galaxies may also help clarify what causes the distinct red hue observed in small red dots, which is altered to a red wavelength as it passes through surrounding gas clouds encircling the black hole.

“I’ve observed these clouds in other galaxies,” Dr. Taylor stated.

“When I compared this object to others, it was unmistakable.”

Capers-LRD-Z9 merits attention due to the immense size of its black hole.

It’s estimated to be as massive as 300 million solar masses, equating to half the total star mass within the galaxy. This size is notably large, even among supermassive black holes.

By discovering such massive black holes early on, astronomers provide a unique opportunity to investigate the growth and evolution of these entities.

Black holes existing in later epochs had diverse opportunities for growth over their lifetimes, yet this was not the case during the initial hundreds of millions of years.

“This reinforces the increasing evidence that early black holes grew much faster than previously believed,” Dr. Finkelstein mentioned.

“Or they might have originated much larger than our models suggested.”

These findings are detailed in a paper published in the Astrophysical Journal.

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Anthony J. Taylor et al. 2025. Capers-Lrd-Z9: Gasensing Little Dot hosts Broadline’s active galactic nucleus at z = 9.288. apjl 989, L7; doi: 10.3847/2041-8213/ade789

Source: www.sci.news

Paleontologists Uncover a New Species of Iguanodon Dinosaur

A collaborative team of paleontologists from Portugal, Italy, the United States, and Belgium has enriched their paleontological records with the identification of a new herbivorous dinosaur species: Cariocecus bocagei.



Cariocecus bocagei. Image credit: Victor Feijó de Carvalho.

Cariocecus bocagei inhabited what is now known as Portugal during the Valemia period of the Cretaceous, approximately 125 million years ago.

This newly identified species belonged to the medium-sized Iguanodon group, which includes robust herbivorous dinosaurs with intricate teeth structures.

“The Iguanodon faction plays a significant role in the herbivorous dinosaur fauna across various ecosystems of the Cretaceous period,” stated Dr. Filippo Bertozzo, a paleontologist at the Royal Institute of Natural Sciences and ci2paleo (Centro de Perebierosia de Nature Ecology, Paleontology of Rehabilitation Therapy).

“At the conclusion of the Jurassic, the Iguanodon factions exhibited limited diversity and body size, with the largest being Camptosaurus.

“These dinosaurs were primarily restricted to the central part of the northern landmass of the Jurassic, which now includes modern-day Wyoming, Tanzania, and Portugal.”

“By the mid-Cretaceous, these clades had achieved a worldwide distribution,” they further commented.

“The selective pressures and environmental factors that drove this diversification during the Jurassic to Cretaceous transition remain poorly understood, largely due to the scarcity of iguanodontian fossils in various regions, such as South Africa.

“The Iguanodon faction was among the first dinosaurs to be discovered and researched, with ongoing studies aimed at exploring the anatomical features and their functions,” they remarked.

“Nonetheless, various aspects of the skull, from the function of the supraorbital bone to paleoneurology and sensory systems, continue to be elusive.”



Digital reconstruction of the skull of Cariocecus bocagei. Image credit: Bertozzo et al., doi: 10.1080/14772019.2025.2536347.

The partial skull of Cariocecus bocagei was uncovered in 2016 along the cliffs of West Portugal from the Paposeco Formation.

This specimen, measuring approximately 37 cm long, is the first Iguanodontian skull recorded in the country.

“The specimen was excavated from the Seco Formation of Papo along the southern coast of the Setubal Peninsula, roughly 200 meters north of Praia de Areia do Mastro,” noted the paleontologist.

“A comprehensive sequence analysis indicates that the early Cretaceous layers found along this coastline were deposited during the fourth and final uplift episodes related to the formation of the Lusitania Basin.”

Upon examining the fossils, researchers identified anatomical characteristics not observed in other Iguanodon species.

“The upper jaw and Jugal bones are flawlessly fused. I have never encountered this in any other iguanodon,” Dr. Bertozzo expressed.

“This isn’t a random anomaly; it’s a genuinely unique feature, confirming it as a new species.”

MicroCT scans enabled scientists to explore the cranial nerves and inner ear with remarkable detail.

“A skull discovery is always significant. It reveals much more than isolated bones,” Dr. Bertozzo commented.

“In this instance, you can observe the impressions of the brain and nerves and even reconstruct parts of the inner ear.”

“The structure of the balance organs and auditory nerves offers insights into how this animal lived and oriented itself.”

“Another notable feature is the unusually low ‘brow’ bones, lower than those of other known Iguanodon factions.”

“This likely supported a heavy brow ridge akin to that of modern eagles.”

“Such structures may have implications for functionality or visibility.”

“The teeth of Cariocecus bocagei also provided remarkable insights,” he added.

“MicroCT scans uncovered not only visible teeth but also replacement teeth embedded within the jaw, designed to replace those that have worn down.”

“This tooth replacement mechanism is characteristic of iguanodons but is rarely observed in earlier species.”

The research team speculates that Cariocecus bocagei may have possessed a stronger bite relative to its kin.

“The discovery of Cariocecus bocagei enhances our understanding of the ecological dynamics within the Lusitania Basin’s early Cretaceous environment, indicating the presence of multiple Iguanodon species, reflecting trends seen in other symbiotic habitats in the UK, Belgium, Spain, and Central Africa,” the authors stated.

“The Valemian diversity in Iguanodon taxa resulted from island endemic events that emerged following the dispersal of dry morphs in North America during the Late Jurassic and Late Cretaceous periods.”

“In conclusion, the discovery of Cariocecus bocagei emphasizes the significance of the Balemian Psien of Hauteribia in the diversification and speciation of Iguanodonians, ultimately leading to the evolution of the more advanced Hadrosaurus in the Turonian period.”

Survey results were published in the Journal of Systematic Palaeontology.

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Filippo Bertozzo et al. 2025. Cariocecus bocagei, a new basal hadrosauroid from the Lower Cretaceous period of Portugal. Journal of Systematic Palaeontology 23(1); doi:10.1080/14772019.2025.2536347

Source: www.sci.news

U.S. Rivers Face Unprecedented and Severe Impacts from Global Warming

Rivers across the United States are experiencing increasing temperatures.

A recent analysis of nearly 1,500 river locations spanning over 40 years reveals a rise in the frequency, intensity, and duration of heat waves, posing risks to many species accustomed to cooler waters.

“The increase in river heat waves is actually outpacing that of air heat waves, which is quite surprising,” states Li Li, a professor of environmental engineering at Pennsylvania State University and the study’s author.

A new analysis published in the peer-reviewed journal Proceedings of the National Academy of Sciences is the first comprehensive study defining river heat waves as five consecutive hot days compared to seasonal averages.

The researchers identified climate change, which significantly impacts humans, as a major contributor to this trend, due to diminishing snowpacks and slower stream flows.

Human factors also play a role; for example, dams inhibit downstream flow, while urban structures absorb heat, warming both air and water.

Scientists are concerned that species reliant on cold water, such as salmon and trout, will increasingly struggle as river temperatures rise. Li emphasizes the necessity of tracking fish fatalities and ongoing trends.

Higher temperatures decrease the amount of dissolved oxygen in water. Additionally, cold water species generally exhibit increased metabolism in warmer conditions, leading to further oxygen depletion.

These findings could influence basin management strategies and help determine if adjustments in irrigation or dam releases can support aquatic life during elevated temperatures.

“Water management practices can significantly impact heat waves,” noted Jonathan Walter, a research scientist at UC Davis’ Center for Watershed Sciences, who was not part of the study. “If there is sufficient reservoir water, it may be feasible to moderate downstream temperatures by releasing water to mitigate extreme heat.”

While heat waves in oceans and lakes have been studied extensively, there has been limited research on the implications of rising temperatures in rivers until now.

Satellite data have advanced the study of ocean and lake heat, but river temperature research is challenged by reliance on often unusable river gauge sensors, resulting in significant data gaps.

For this new study, researchers analyzed data from 1,471 US Geological Survey monitoring sites from 1980 to 2022.

This data enabled an assessment of shifts in streams nationwide, revealing that by 2022, river heat waves were occurring more frequently than in 1980, with an average increase of 1.8 additional heatwave events per year. These heat waves were also more severe, with temperatures during these events being approximately 0.8 degrees Fahrenheit higher in 2022 than in 1980. Moreover, the duration of heat wave events extended by over three days.

Li noted that this extra heat caused an average of about 12 days of heat stress for cold water species. The study defined 59°F as the threshold for heat stress, as many species, including bull trout, face survival challenges at this temperature.

“When considering water, its visibility draws attention to its significance,” Li remarked. “We hope this research raises public awareness on water quality challenges stemming from climate change.”

Source: www.nbcnews.com

Strange Discovery: Venus Features a Lava Tube

SEI 267222984

We are gaining knowledge about Venus, a high-pressure planet

JSC/NASA

There is compelling evidence that vast underground tunnels have been formed from lava on Venus. These formations are unusually wide and distinct from those found on other celestial bodies.

It is generally accepted that underground tunnels, carved through lava, exist as lava tubes on Earth, the Moon, and Mars. Smaller, low-gravity planets tend to develop more porous tubes as their rocky walls are less susceptible to collapse due to weaker gravity. For instance, the Moon has such large tubes that scientists have proposed utilizing them as habitats for astronauts, shielding them from intense solar winds.

Researchers have observed indications of these lava tubes on Venus, evident from surface holes that may have been formed by the underground features or by other geological activities associated with its active fault lines.

Recently, Barbara de Tofoli from the University of Padova in Italy along with her colleagues uncovered direct evidence of these lava tubes on Venus. Remarkably, despite Venus’s similarities to Earth regarding its mass and gravity, its lava tubes appear to be surprisingly wide, with a volume comparable to those found on the Moon.

“While Earth has a small number of lava tubes, Mars has a slightly larger count, and the Moon has even more. Venus disrupts this trend by featuring incredibly large tubes, indicating its potential significance,” she stated at the Europlanet Science Congress in Helsinki, Finland, earlier this month.

De Tofoli and her team used radar and mapping data from previous missions to examine the alignment of these pits near large volcanoes. They identified four distinct sites where alternative geological explanations, such as structural activities, were implausible. The pits were also found to align with the steepest sections of volcanic slopes, consistent with the movement of lava. Their depth-to-width ratio corresponded with known lava tubes.

The unexpectedly large size of these tubes, especially their width, implies that the extreme conditions on Venus, characterized by high temperatures and pressure, can influence the movement of molten rock beneath the surface. “Due to the extremely high pressure, the floor of these tubes is not eroded as intensely as it typically is on other planets; instead, it remains largely flat throughout the tube.”

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Source: www.newscientist.com

Scientists Reveal That Liquid Water Once Flowed Through the Parent Body of Asteroid Ryugu

This water flow took place on ancient asteroids over a billion years after their formation, likely due to the heat generated by melting ice, which caused rock fractures that facilitated water movement. JAXA’s Hayabusa-2 Spacecraft.

This image of the asteroid was taken on June 26, 2018, by JAXA’s Hayabusa-2 Spacecraft optical navigation camera – telescopic (ONC-T). Image credits: JAXA / University of Tokyo / Kochi University / Ricchiho University / Nagoya University / Chiba University of Technology / Nishimura University / Aizu University / AIST.

Ryugu is a CG-type asteroid close to Earth and part of the Polana family of impact asteroids.

The diamond-shaped body, also known as 1999 JU3, was identified by astronomers in May 1999 during asteroid studies near Lincoln.

Its diameter measures about 900 m (0.56 miles), and it orbits the Sun at a distance of 0.96-1.41 Astronomical Units (AU) every 474 days.

“We have a relatively good understanding of how the solar system was formed, though many gaps remain,” said Shiyoshijima, a researcher at the University of Tokyo.

“One gap in our knowledge is how Earth acquired its water.”

“It has long been known that carbonaceous asteroids, originating from ice and dust in the outer solar system, have contributed water to Earth.”

“We discovered that Ryugu preserves an unaltered record of water activity, indicating that liquid water moved through the rock much later than previously anticipated,” added Dr. Ikemoto.

“This shifts our understanding of the long-term fate of water on asteroids. The water has remained for an extended period and hasn’t been depleted as quickly as we thought.”

In this study, the authors examined the isotopes of lutetium (Lu) and hafnium (HF), with the radioactive decay from lutetium-176 to hafnium-176 serving as a sort of clock to gauge geological processes.

The expected presence of these isotopes in the studied sample was hypothesized to correlate with the asteroid’s age in a predictable manner.

However, the ratio of Hafnium-176 to Lutetium-176 was significantly unexpected.

This strongly suggests to researchers that the liquid effectively washed away lutetium from the rocks containing it.

“We anticipated that Ryugu’s chemical signatures would align with certain meteorites currently under examination on Earth,” Dr. Iizuka stated.

“However, the results were strikingly different, necessitating the careful elimination of other possible explanations, ultimately concluding that the Lu-HF system was hindered by a delayed liquid flow.”

“The most probable triggers involved the parent body of Ryugu’s larger asteroid, which disrupted the rocks, melting the embedded ice and allowing liquid water to permeate the body.”

“It was truly surprising! This impact event could be the catalyst for the parent body disruption.”

One of the crucial implications is that carbon-rich asteroids may be a significant source of water for Earth, supplying far more than previously estimated.

Ryugu’s parent body seems to have retained ice for over a billion years. This suggests that similar bodies impacting the young Earth could have delivered 2-3 times more water than standard models predict, significantly influencing the planet’s early oceans and atmosphere.

“The notion that a Ryugu-like object has preserved ice for such an extended time is remarkable,” Dr. Ikemoto remarked.

“It implies that Earth’s components were far wetter than we had imagined.”

“This prompts a reevaluation of the initial conditions for the planetary water system.”

“It’s still early to draw definitive conclusions, but my team and others may build on this research to clarify various aspects, including how our planet became habitable.”

The findings will be published in the journal Nature.

____

T. Iizuka et al. Late fluid flow of primitive asteroids revealed by Lu-HF isotopes of Lu. Nature. Published online on September 10th, 2025. doi:10.1038/s41586-025-09483-0

Source: www.sci.news

How Do Small Galaxies Acquire Their Magnetic Fields? – Sciworthy

Among the four fundamental forces in the universe, gravity often comes to mind when considering cosmic phenomena. This is quite logical, as gravity operates over vast distances, exerting its influence on massive objects, making it the most significant and far-reaching force. However, another essential force, known as electromagnetism, also plays a critical role in the study of space.

To begin with, all light is made up of electromagnetic radiation, which consists of oscillating electric and magnetic fields. This includes everything from radio waves to visible light and X-rays. Similar to Earth and the Sun, many celestial bodies are enveloped in magnetic fields. The Earth’s magnetic field serves as a shield against harmful radiation, while the solar magnetic field repels it. The generation of a magnetic field requires the movement of charged particles, such as protons and electrons. Consequently, a variety of objects, including entire galaxies, possess magnetic fields!

Researchers are aware that galaxies have magnetic fields, but it remains uncertain how various galaxies develop different magnetic intensities or how these fields influence their evolution over time. This investigation is further complicated by the fact that galaxies often exist in clusters. For instance, the Milky Way is surrounded by smaller galaxies known as satellites, which exert gravitational pull on each other and interfere with each other’s magnetic fields.

The research team explored how diverse environments in smaller galaxies affected the strength of their magnetic fields. They approached this by simulating the motion of materials within the galaxy as if they were liquids filled with striped particles. Two sets of simulations were conducted, the second of which also included the effects of high-energy particles known as cosmic rays.

In total, they simulated magnetic fields across 13 distinct scenarios, ranging from isolated galaxies with masses 10 billion times that of the Sun to those 10 trillion times greater, accompanied by up to 33 satellites. Each simulation commenced with galaxies exhibiting a magnetic field strength of 10-14 Gauss (g). For context, Earth’s magnetic field strength is about 0.3-0.6 g. The scenarios were evolved over 12 billion simulation years, allowing galaxies to interact, traverse space, and form stars, subsequently tracking the magnetic field strength in smaller galaxies.

Throughout the simulated timeline, the magnetic fields of all galaxies strengthened as star formation progressed. The birth of stars stirs the galactic matter, enhancing magnetic field strength and producing cosmic rays. Most galaxies concluded with magnetic fields ranging from 10-7 to 10-6 G, with larger galaxies typically achieving stronger fields. Interestingly, the researchers found that small galaxies passing in close proximity to larger companions exhibited stronger magnetic fields than equivalent isolated galaxies.

They monitored satellite galaxies over a series of simulations and discovered that, on average, magnetic field strength increased by 2-8 times as these galaxies approached their host. In extreme cases, the satellite’s magnetic field intensified by up to 15 times after nearing the host. In contrast, satellite galaxies that were more distant or had not yet approached their host did not show such significant increases in magnetic field strength.

The researchers interpret their findings to suggest that the more turbulent the interstellar medium (ISM) within a galaxy, the greater the strength of its magnetic field. Orbiting near a host galaxy tends to disturb the ISM of the satellite galaxy, rendering it more magnetic than a solitary small galaxy. Approaching a massive galaxy compresses the satellite, exposing it to magnetizing materials, and both interactions contribute to amplifying the magnetic field strength.

The team recommends that future studies utilize these results to inform radio and gamma-ray observations of galaxies, as these two segments of the electromagnetic spectrum can provide astronomers insights into the magnetic field properties of celestial bodies. They also caution that astronomers conducting simulations of isolated galaxies might yield skewed results since such a scenario does not accurately reflect the reality in which many galaxies are in proximity to companions.

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Source: sciworthy.com

Amazon Deforestation Leads to Severe Rain, Wind, and Heat Events

Illegal deforestation in the Amazon of Mato Grosso, Brazil

Paralaxis/Alamy

Life in the Amazon post-deforestation presents a grim scenario. Strong winds impede the recovery of the forest, while rising temperatures result in heat stress for both inhabitants and wildlife.

This contradicts the common belief that rainforest removal leads to a drier local climate.

Many studies suggest that deforestation in the Amazon will significantly reduce rainfall, but these studies often rely on low-resolution models that fail to accurately depict convection patterns in the region.

Recently, Alim Yun from the Max Planck Institute for Meteorology in Germany and her team have employed advanced climate models to represent rainforest rainfall dynamics and convection more accurately.

Dominic Spracklen, at the University of Leeds in the UK, which was not involved in the study, regards this methodology as “highly commendable,” suggesting it could “enhance predictions of climate responses to deforestation.”

Using this innovative approach, Yoon previously reported that under current climatic conditions, a complete deforestation of the Amazon would yield relatively stable average annual rainfall. The ongoing research aims to analyze how hourly patterns of rain, heat, and wind shift in this complete deforestation scenario.

The team’s findings indicate an increase in the frequency of dry spells, with a 54% rise in severe rainfall events. Concurrently, daily temperature extremes rise by 2.7°C (4.9°F) and 5.4°C (9.7°F), significantly heightening heat stress among local populations. Moreover, extremely strong winds are becoming more prevalent.

Over 30 million individuals reside in the Amazon region, including around 2.7 million indigenous people. “Expect intensified rainfall and extreme temperatures,” warns Lewis Catterrand from the University of Leeds. “This is alarming for everyone in the area.”

However, he cautions that further validation of this modeling approach is necessary. Additional research is essential to explore the effects of partial deforestation on the local climate in light of future projections for the region. “These extreme scenarios are meant to aid scientists in understanding the implications, but we know they don’t paint a complete picture,” says Catterrand.

Topic:

  • Forest destruction/
  • Amazon rainforest

Source: www.newscientist.com

Three Essential Guidelines for an Effective Post-Workout Diet

Are carbohydrates, proteins, and liquids the foundations of your post-exercise diet?

cream_ph/getty images

When it comes to exercise, I’m not particularly focused on enhancing my performance or optimizing my biology. My primary goal is simply to remain active. Consequently, I have not given much thought to my post-exercise nutrition. However, training for a half marathon has illustrated to me the significance of properly fueling my body, and that it doesn’t need to be complicated.

It’s essential to understand that your post-exercise nutritional requirements can differ based on several factors, including the type of exercise you engage in, your age, gender, genetics, and more. Nonetheless, an April review in Sports Medicine discovered compelling evidence regarding three key interventions that enhance muscle recovery and performance. I consider these as foundational elements of a post-exercise diet.

The first element is carbohydrates. During exercise, your body taps into energy stores found in the liver and muscles. Replenishing these stores is vital to prevent muscle breakdown and ensure adequate energy for your next workout. Carbohydrates serve as the most effective source of this energy because they are quickly converted into usable fuel.

The review suggests that after four hours of intense exertion, athletes should consume 1-1.2 grams of carbohydrates per kilogram of body weight per hour. While this guidance may be geared more toward athletes, it’s advisable for all adults to consider a carbohydrate-rich snack or meal post-exercise. Opt for options that include both glucose and fructose, as glucose helps restore muscle energy and replenishes liver stores. Fruits are perfect, as they provide both.

The second element is protein, which is crucial for muscle recovery. Combining protein with carbohydrates has been shown to enhance performance. A 2016 study involving eight athletes indicated that those who consumed both macronutrients within two hours after an intense cycling session could ride an average of 14 minutes longer in their subsequent workout compared to those who only ingested carbohydrates. The timing of protein intake matters less than the quantity consumed. Reviews in Sports Medicine recommend 20-40 grams of protein after exercise.

study involving 72 men (also published in 2016) demonstrated that oral supplement solutions, milk, and orange juice were found to be more hydrating than water due to their electrolyte content, which aids in hydration and retention. Beverages like tea, coffee, soft drinks, and even beer provided hydration levels similar to water. Though I’m not advocating for pints post-workout, if water isn’t appealing, choose something delicious that you enjoy.

I still prefer simplicity, but now I focus on these three core elements. My favorite choice is a smoothie made with frozen fruits, orange juice, and protein powder. Although it’s not perfectly optimized, it represents an improvement. And it always satisfies my cravings after a run.

Grace Wade is a health reporter for New Scientist based in the US.

For more projects, please visit newscientist.com/maker

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Books vs. Audiobooks: Is Reading Always More Beneficial for the Brain Than Listening?

Engaging with information can alter how your brain processes and reacts to it

Tony Anderson/Getty Images

As a passionate reader and writer, I often find myself disheartened. Recent reports indicate a decline in reading for enjoyment among younger generations. When a friend asked if her use of audiobooks provided the same cognitive benefits as traditional reading for her daughter, my initial thought was, “Enjoyment matters more than the format.” However, exploring the science revealed that the medium indeed influences our cognitive process in important and distinct ways.

The Advantages of Reading

Reading unquestionably benefits us. Aside from the knowledge it imparts and the opportunities it opens up, numerous studies link childhood literacy with both physical and mental well-being – and even extended lifespans.

It is believed that reading exercises three crucial cognitive functions. Firstly, it promotes “Deep Reading,” allowing us to connect different sections of text, reflect on their relevance to our lives, and engage with the material critically.

Secondly, reading fosters empathy and bolsters our emotional intelligence—traits that are essential for coping with stress and navigating real-life difficulties. Thirdly, there exists a correlation between reading and cognitive development. The “Theory of Mind” refers to our ability to recognize that others may hold different thoughts and beliefs than we do.

However, discerning the impact of reading from other influences can be challenging. Moreover, readers may enjoy advantages like having leisure time, financial resources, or even genetic traits which can affect overall health, cognition, or longevity.

Nevertheless, a study involving over 3,500 participants attempted to account for these factors, revealing that individuals who read for approximately 30 minutes each day were 20% less likely to pass away in the subsequent 12 years. This benefit was more pronounced among book readers compared to those who primarily read newspapers and magazines.

Digital Media: E-readers and Audiobooks

Comparing print reading to digital formats complicates the research landscape. Some studies suggest that screen reading promotes a more superficial understanding compared to reading printed material.

There are also subtle differences. In a series of experiments conducted by Anne Mangen from Stavanger University, Norway, and Frank Hakemalder from Utrecht University in the Netherlands, it was found that frequent readers of short texts on screens tended to seek meaning less diligently than their paper-reading counterparts. Additionally, increased exposure to screen reading correlated with diminished persistence in tackling longer literary works.

Concerning audiobooks, while the evidence remains limited, I find some solace in the findings. Research indicates that comprehension levels are very similar whether one is reading or listening. However, some nuances exist—meta-analyses of 46 studies discovered that reading provides a slight advantage for interpreting the emotions of characters, among other interpretative skills. Thus, drawing inferences from the text is somewhat more effective when reading.

Diverse Cognitive Approaches

Interestingly, listening rather than reading seems to engage different cognitive aspects. For instance, research shows that individuals tended to think more intuitively when responding to verbal questions compared to written ones.

Listening to an audiobook provides the experience of hearing another person’s voice with its unique intonations, rhythms, and emotions, which can greatly influence interpretation. Janet Gaipel from the University of Exeter notes that contrastingly, reading relies on our inner voice, allowing for a more individualized and self-paced experience. These distinctions may significantly affect how information is perceived and utilized.

Nonetheless, “listening to audiobooks is not somehow detrimental,” Geipel argues. “The real issue lies in how you allocate your attention. Listening can be just as effective as reading if you are fully focused, but multitasking while listening can compromise depth compared to immersive reading without distractions.”

Finding What Works for You

Listening alongside reading introduces yet another layer. A meta-analysis conducted by Virginia Clinton Lisell at the University of North Dakota found that while combining listening with reading might yield slight improvements in understanding, this is likely only true for those who struggle with decoding text, such as individuals with low literacy or those learning to read in a non-native language. For skilled readers, however, this dual engagement may lead to diminished comprehension due to “cognitive load theory,” where presenting information in two formats can create redundancy and overwhelm cognitive resources.

Ultimately, various factors—dyslexia, visual impairments, lengthy commutes, or personal preference—can drive the choice for audiobooks rather than print. As for whether you derive equivalent benefits, “there’s no straightforward answer,” Geipel acknowledges.

If options are available, I suggest reserving an engaging podcast or a thought-provoking book for moments of focus, rather than while preparing dinner. However, if someone is immersed in a story purely for enjoyment, as in the case of my friend’s daughter, choosing an audiobook appears to be a far better alternative than missing out altogether.

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Source: www.newscientist.com

The Only Earth Creatures Capable of Surviving on Mars

Mars is a quite an intimidating environment for life forms accustomed to Earth. The average surface temperature hovers around -63°C (-81°F), and temperatures only manage to rise slightly above freezing near the equator during summer.

Moreover, the atmospheric pressure is equivalent to that found on Earth at an altitude of 35km (almost 115,000 feet), well above the cruising altitude of commercial flights. This sparse atmosphere is predominantly carbon dioxide, containing only minimal amounts of oxygen.

Additionally, liquid water is virtually nonexistent on Mars, with radiation levels being 400 times greater than those on Earth, and only rare instances of extremely saline trickles.

Nonetheless, certain Earth organisms have shown a remarkable ability to endure such harsh conditions.

The European Space Agency conducted a series of experiments between 2008 and 2016, exposing various organisms and seeds to simulated Martian conditions aboard the International Space Station.

Tardigrades, fungi, and some bacteria survived for over a year, but solely in dormant forms, such as spores and cysts.

Some lichens and algae went a step further, demonstrating actual metabolic activity when partially shielded from radiation—this could occur on Mars if they are embedded in soil or hidden within rock crevices.

In 2024, Chinese researchers discovered that various desert moss species (Syntrichia caninervis) could endure simulated Martian conditions. However, “tolerance” is far from thriving in such an environment.

Although the moss was able to recover after a week in the simulated Martian environment and returned to normal growth, researchers did not find evidence of metabolic activity, such as oxygen production, within the Martian setting.

But the challenges are even greater.

Mars has an average surface temperature of -63°C (-81°F) and an atmospheric pressure that corresponds to 35km (nearly 115,000 feet), along with radiation levels that are 400 times higher than on Earth.

Mars soil contains perchlorate, a problematic oxidizer that is toxic to cell functions and leads to DNA damage. Exposure to the ultraviolet radiation prevalent on Mars makes it even more reactive.

The Chinese experiments did not simulate perchlorate presence in the Martian environment. Had it been included, it likely would have obliterated the moss entirely.

Some fungi survive perchlorate, and several bacterial species can utilize it as an energy source, even breaking it down into harmless by-products. However, these species still require water and warmth to thrive.

Typically, when we store items, we employ various methods to eliminate bacteria and fungi or inhibit their growth.

We freeze food, dehydrate it, sterilize with UV light, soak it in saline solutions, or seal it in oxygen-removing containers. On Mars, all these methods are naturally enforced!

If we aimed to sterilize a planet, we could hardly surpass the existing conditions on Mars.


This article addresses the inquiry posed by Robin Mason of Manchester: “Is there anything on Earth that can withstand Martian conditions?”

Please send your questions via email to Question @sciencefocus.com, or reach us through Facebook, Twitter, or Instagram Page (please include your name and location).

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Mars’ Mysterious Markings: The ‘Most Obvious Signs’ of Alien Life, According to NASA

The unusual “leopard spot” markings on Mars’ rocks might finally indicate that alien microbes could have existed on the Red Planet.

A comprehensive analysis of these rocks has shown that the intricate patterns are “the clearest signs ever found on Mars,” as stated by Sean Duffy, a NASA representative.

These rocks, estimated to be about 3.5 billion years old, were discovered in July 2024 by NASA’s Perseverance rover. Since then, planetary scientists have been exploring various hypotheses to explain these markings.

Recent information from a Nature paper suggests that while the patterns may have a geological origin, the prevailing theory now points toward ancient Martian microbes as the likely culprits.

Perseverance collected rock samples, hoping to yield a more definitive answer. If all goes well, these samples will eventually return to Earth for a thorough examination of potential signs of past life.

Leopard Spots on Bright Angel

Currently, Mars is a barren, lifeless world, but this hasn’t always been the case. Until around 3 billion years ago, Mars’ surface was rich with flowing rivers and expansive lakes.

Wherever there is water on Earth, signs of life typically follow. For two decades, NASA’s rovers have been scouring Mars for evidence suggesting that the Red Planet could have once supported life.

The Perseverance rover is exploring a site known as Jezero Crater, which was a lake in Mars’ ancient history. Similar environments on Earth often serve as habitats for microorganisms.

Within rock formations referred to as the Bright Angel formation, Perseverance uncovered stunning patterns resembling leopard spots.

“We conducted extensive observations of the entire rock formation at Bright Angel,” said Professor Joel Hurowitz of Stony Brook University in the US, in an interview with BBC Science Focus.

While Perseverance’s cameras captured detailed images of the patterns, a spectrometer analyzed the mineral composition. The rover even utilized radar to map the structure of the subsurface outcrop.

“Essentially, we used every tool available on these rocks except for the kitchen sink,” Hurowitz remarked.

The analysis indicated that the patterns were formed by iron-rich minerals called vivianite and greygite. On Earth, these minerals typically arise from “redox reactions,” a process in which microorganisms exchange electrons with their environment.

“On Earth, these reactions are often facilitated by microorganisms residing in sediments, which derive energy from them for metabolic activity,” Hurowitz explained. The residuals from these processes create distinctive patterns in sedimentary rocks.

However, this doesn’t mean we should rush to celebrate the discovery of alien life just yet. There are other mechanisms that could account for the leopard spot patterns without any biological influence.

For instance, heat could have driven reactions between mud and organic matter, resulting in new minerals.

Yet, the research team did not find evidence indicating that the rocks were subjected to heat. Additionally, other methods they investigated also did not seem viable. Nonetheless, Hurowitz cautioned, “We cannot dismiss these entirely.”

One of the most surprising findings is the relatively young age of these rocks. At only 3.5 billion years old, the patterns formed while Mars was already entering a phase of decline, suggesting that the planet may have been habitable for much longer than previously assumed.

Unfortunately, Perseverance has an entire planet to explore and we continue our quest to find life beyond Earth.

Perseverance drilling and photographing rock samples – Credit: NASA/JPL -CALTECH/MSSS

“If I could revisit Jezero in the future, I would have follow-up questions that I would like to address using the rover’s instruments,” Hurowitz remarked.

“However, these follow-up analyses may not necessarily provide a more conclusive answer regarding whether these features were shaped by life.”

“Ultimately, determining whether life was involved will necessitate laboratory analysis back on Earth.”

Bringing Mars to Earth

Fortunately, Perseverance is part of the initial phase of Mars’ sample return mission. Not only is it studying the rocks on Mars, but it’s also preparing to bring samples back to Earth.

Before departing from Bright Angel, the rover collected and stored samples from the rocks along with numerous similar fragments obtained during its mission on Mars.

NASA aims to collaborate with the European Space Agency on follow-up missions to retrieve these samples and return them to Earth where they can be analyzed in top-tier laboratories.

After 3.5 billion years, finding definitive evidence is challenging. Instead, researchers will seek additional signs that microbes may have left behind.

“The first logical step is to analyze the isotopic composition of iron, sulfur, and carbon in the various mineral and organic components of the rock,” Hurowitz stated.

Isotopes can be thought of as different variants of the same element. Microorganisms tend to retain particular isotopes more than their non-biological counterparts, enabling researchers to narrow down their search for evidence of life.

“These variations in isotopic composition are essential tools for investigating biological signals in ancient rocks on Earth, and we aim to apply similar methods to this Martian sample,” Hurowitz noted.

The return mission is tentatively scheduled for the 2030s, although there is a risk of cancellation due to cuts to NASA’s planetary exploration budget during the Trump administration.

“NASA is examining strategies for retrieving these samples and others,” a NASA spokesperson told BBC Science Focus. “Having explored Mars for 60 years, we will continue to look into budgetary and timing considerations for a quick and cost-effective return of these samples.”

“We hope these findings will further motivate the sample return mission,” Hurowitz added. “This will allow us to scrutinize the sample with the detail necessary to determine its historical record of life on Mars.”

“If it’s indeed life, that would suggest our planet is not the only one where life has evolved,” Frowitz concluded. “If life originated twice, how many other places might it have occurred?”

About Our Experts

Joel Hurowitz is an associate professor in the Department of Geoscience at Stony Brook University in New York, USA. He investigates the early history of Mars through measurements taken from planetary studies and Earth’s similar topographies.

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Source: www.sciencefocus.com

Five Incredible Inventions that Turn Humans into True Cyborgs

We already understand how to artificially bring our bodies back to their natural optimal state. Prescription glasses can help correct vision, while hearing aids aid those with hearing loss.

Today, emerging technologies are advancing to enhance the human body more than ever before.

Those who utilize these innovations embody a blend of human and machine, elevating their capabilities to reach what once seemed unattainable.

These are not merely futuristic concepts; they are new technologies available on the market or soon to be released.

I’ll take you to the sky

Flight has been a long-held human aspiration, from Icarus in Greek mythology to flying cars in sci-fi films like Blade Runner. Though personal flight technology may seem fanciful, it exists today in the form of a gravity jet suit.

We once envisioned rocket boots that could lift us off the ground, but such designs would be inherently unstable due to thrust being directed away from the wearer’s center of gravity.

Instead, the Gravity Jetsuit employs five engines that gently assist the wearer in navigating the air. Pilots can hover, spin, and even glide short distances above land or water.

The 1,050 horsepower gas turbine on the back provides essential lift, while two small jet turbines on each arm ensure stability and control.

In 2021, the Royal Navy tested the suit in a training exercise to explore its onboarding potential.

Please close your eyes and look

In the future, this technology could assist individuals with color blindness in perceiving a broader spectrum of colors – Photo Credit: Getty Images

Human vision is relatively limited; without light, we are nearly blind. Night vision goggles have allowed us to see red light wavelengths for some time, but this technology has now been miniaturized.

Chinese scientist developed contact lenses coated with nanoparticles that absorb infrared rays and re-emitt them as visible red, green, or blue light.

In trials, these lenses enabled users to see flashes from an infrared LED.

Interestingly, participants found it easier to see these flashes with their eyes closed, as the visible interference from light was blocked by their eyelids.

In the future, this technology may be adapted to assist those with color blindness in experiencing a wider range of colors.

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I’m walking towards the future

Exoskeleton suits are wearable machines designed to enhance natural strength. Think of them as a type of powered suit or wearable forklift.

Many associate them with sci-fi movies like Alien, but they are already in use today.

Exoskeleton sensors detect the wearer’s movement and activate joint motors to provide additional strength.

Exoskeleton sensors detect your movement and activate the joint motors to provide added strength – Image Credit: DNSYS

Exoskeleton technology currently assists some individuals with disabilities, enabling them to function without assistance. It is also being developed to help warehouse workers lift and move heavier objects safely.

Moreover, this technology has everyday applications, such as aiding individuals in hiking longer distances or navigating stairs that might otherwise be challenging.

Get a better grip

Scientists at University College London recently created a glove-like device that provides the wearer with an additional thumb.

Researchers from University College London developed a glove-like device that provides the wearer with an extra thumb – Image credit: Dani Close/UCL

While this may appear redundant (as most of us already possess two), tests show that the additional thumb enhances dexterity, allowing tasks to be completed more easily with two hands.

Sensors located beneath the wearer’s toe control the movement of the third thumb. Currently, there is no tactile feedback, meaning the wearer cannot yet use it for delicate tasks, like carrying eggs.

Though the third thumb is not part of our natural anatomy, participants have quickly adapted to using it; only four out of nearly 600 individuals could not operate it successfully.

Control things with your thoughts

Brain Control Interface Technology allows individuals with neurodegenerative disorders reliable control over their surroundings – Photo Credit: Case Western Reserve University

Brain Control Interface (BCI) is an innovative technology that enables individuals to control computers using their thoughts.

By embedding microelectrodes into the brain, nerve signals associated with limb movement can be decoded by computers and used to manipulate external devices.

This technology enhances far more than just computer usability; it offers those with neurodegenerative conditions reliable control over their environment.

So far, this technology has allowed volunteers with spinal cord injuries to control computer cursors merely by thinking of movements associated with their paralyzed hands or arms.

The next evolution for these devices is the precise control of robotic limbs. With BCI technology, scientists envision a future where patients with muscle atrophy or other degenerative conditions fully regain their motor capabilities.

read more:

Source: www.sciencefocus.com

Experts Caution Against Earlier and Shorter Seasons

This autumn, New England’s renowned leaf spectacle may not extend as long as Leaf Peepers hope. Following a summer marked by drought and fluctuating rainfall, experts anticipate that colors will emerge early, shine brightly, and fade more quickly than usual.

Timing is not just essential for Instagram-worthy shots. Annually, millions flock to New York, Vermont, Massachusetts, New Hampshire, and Maine to hike, drive, and explore under the vibrant canopy, contributing an estimated $8 billion to the local economy, according to the US Forest Service.

However, this year, scientists say the iconic display is less predictable, with sporadic bursts of color replacing the usual weeks of vibrant waves of red, orange, and gold.

“Bright, Short, Early” season

Jim Salge, an autumn leaves predictor for Yankee magazine, forecasts the transition to be “bright, short, and fast.” Some leaves have already turned brown before showcasing their vibrant hues.

“Traditionally, we observe changes moving northward, inland, and in coastal areas, but as trees become stressed and change rapidly, we expect to see more patchwork patterns this year,” Sarji noted.

When trees do not receive adequate water, they become “stressed,” impairing the process of photosynthesis, which converts sunlight into energy. Conversely, excessive water can suffocate roots.

For optimal viewing, I suggest heading to the western parts of Maine, southern New Hampshire, and northern Massachusetts, as well as the White Mountains in Vermont.

Peak colors are expected to shift to Vermont, New Hampshire, and Western Maine by early October, with higher elevations predicted to peak about a week earlier than usual.

“The silver lining about New England is that if you miss it, you can always head further south,” he said. “If it’s too early, go north or ascend to the mountains.”

Travelers can keep track of leaf changes with tools like the Peak leaf map by Yankee Magazine and I Love New York’s weekly reports.

Why are the leaves changing?

Nonetheless, climate change has generally intensified over recent decades, and this year’s dry summer has accelerated the timeline.

“Ideally, our forests would benefit from a mild rain event evenly spread throughout the year,” explained Mukundrao, assistant professor at Columbia University’s Lamont-Doherty Earth Observatory. “However, a series of extreme storms, followed by dry spells, makes it too rapid for the soil to absorb the water.”

Vibrant leaf colors thrive on warm days and cool nights, but stressful conditions for trees can hasten leaf drop. Stressed or unhealthy trees often exhibit shorter transitions and dull foliage, Rao mentioned. In contrast, urban trees typically retain color longer, as buildings and pavement hold heat while streetlights provide extra illumination.

Additional threats include fungal diseases from heavy spring rains and diseases affecting beech trees.

“We are witnessing invasive insects altering forests and decimating various tree species, alongside invasive plants disrupting native growth and patterns,” Sarji stated.

Tracking changes

To make predictions, Salge depends on weather forecasts and phenotype data, which involves tracking seasonal life cycles.

Notably, Polly’s Pancake Parlor in Sugar Hill, New Hampshire, has been monitoring local foliage since 1975. Records indicate that peak colors appeared for two weeks in late September that year; however, in 2024, it shifted to just two days in early October.

The US National Phenology Network gathers and shares observations from across the country. Its Nature’s Notebook app invites volunteers to document seasonal changes, bolstering over 200 scientific studies, according to director Theresa Crimmins.

“We have a general understanding of nature,” Crimmins remarked. “However, when focusing on specific species in particular locations, there remains much we do not comprehend.”

The revamped version of the app, launching this spring, allows users to upload photos for even one-time observations.

“More people can now become citizen scientists,” Sarji commented. “Their perspectives on the world contribute valuable data.”

Source: www.nbcnews.com

Implications of Trump’s Space Strategy for Future Mars Missions

Since January 2025, when Donald Trump returned to the White House, his administration has enacted severe funding cuts across various federal agencies, including NASA. The proposed 2026 Budget plans to decrease NASA’s institutional funding by as much as 24.3%.

This translates to a financial drop from $24.8 billion (£18.4 billion) allocated by Congress in 2025, to $18.8 billion (£13.9 billion) in 2026.

The president’s proposals are not law until they pass through Congress, where they will be scrutinized, debated, and revised in the coming months.

Nonetheless, this situation focuses attention on some key priorities Trump has outlined during his two terms in office.

Focus on Human Spaceflight

During Trump’s first term from 2017 to 2021, NASA’s budget increased from $19.5 billion (£15.5 billion) to $23.3 billion (£18.5 billion), which constitutes about 0.48% of federal spending.

Trump has reinstated the National Space Council, shaping US space policies with the US Space Force consolidating national security assets in the latest military setup.

His administration emphasizes human spaceflight, launching NASA’s Artemis program aimed at returning humans to the moon by 2024.

Although this timeline appears overly ambitious, Artemis II is still scheduled for a crewed mission around the moon in 2026. If all goes well, Artemis III may land on the lunar surface a few years later.

Near the close of his first term, Trump formalized the National Space Policy, committing to lunar exploration and future missions to Mars. This policy streamlined regulatory frameworks, increasing accessibility for the private sector.

Support for human spaceflight and exploration carried on into his second term.

In April, when announcing the NASA Budget, the White House asserted its intention to return American astronauts to the moon “before China,” which has ambitious plans for a lunar base by the 2030s.

“The proposal includes investments to pursue lunar and Mars exploration simultaneously but prioritizes vital science and technology research,” stated NASA Administrator Janet Petro, reinforcing that the agency would “continue to progress towards achieving the impossible.”

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Risk Projects Due to Budget Cuts

However, the budget cuts may hinder NASA’s ability to meet its goals, as it calls for “rationalizing the institutional workforce” while cutting many support services, including IT and maintenance.

The budget suggests cancelling the costly and delayed Space Launch System (SLS) rocket and the Orion Crew Capsule, both essential for long-range space missions like Artemis.

Instead, it proposes replacing them with “a more cost-effective commercial system” to facilitate subsequent missions.

According to the White House, SLS is operating at 140% over budget, costing $4 billion (£3.2 billion) per launch.

The SLS rocket completed an unmanned Artemis I mission in 2022, but as Trump’s budget advances, Artemis II will send astronauts Reid Wiseman, Victor Glover, Christina Koch, and Jeremy Hansen around the moon in 2026, with plans for lunar landings to follow.

Eliminating SLS and Orion, referred to as the “Legacy Human Exploration System” in Trump’s budget, could save $879 million (£698.5 million).

Artemis I’s Space Launch System Rocket Launch – Photo Credit: NASA

However, US lawmakers have expressed concerns about terminating the program, despite its notable expenses, as it has taken a decade to prepare for the flight, and cancellation could grant China a competitive advantage.

This sentiment was echoed by Texas Senator Ted Cruz: “It’s hard to think of more devastating mistakes,” he remarked during an April Senate hearing.

Another project earmarked for termination is the Lunar Gateway, a new space station intended to orbit the moon. Key hardware for this initiative has already been constructed in the US, Europe, Canada, and Japan.

While some missions might be salvaged, these cancellations risk alienating international partners that NASA has built relations with over decades.

Is There No More NASA Science?

The budget also threatens significant cuts to NASA’s Earth and Space Science Programs, with funding for the former at £1.16 billion (£921.7 million) and the latter at £2.655 billion (£2.1 billion).

“Are Mars and Venus habitable? How many Earth-like planets exist? We’re opting not to find out; such questions will remain unanswered,” the critique suggests.

The budget aims to terminate “multiple, affordable missions,” including long-term endeavors like the Mars Sample Return (MSR), which was deemed unsustainable.

This mission aims to uncover significant information about Mars’ past by analyzing rock and soil samples already collected by rovers currently exploring the planet.

Nonetheless, NASA acknowledged last year that the estimated cost of the MSR mission ballooned from $7 billion (£5.6 billion) to $11 billion (£8.7 billion), with its timeline pushed back from 2033 to 2040.

The proposed budget suggests that MSR goals may be achieved through crewed missions to Mars, aligning with Trump’s promise to “send American astronauts to plant the stars and stripes on Mars.”

However, China’s plans for a Mars sample return mission remain robust, with aspirations for execution in 2028, potentially prompting Congressional pushback against the MSR budget cancellation.

In Earth Sciences, the budget proposes cuts to various Earth monitoring satellites, many vital for tracking climate change.

Ground crews assist 19 astronauts as they return to Earth in April after a successful six-month mission aboard China’s Tiango Space Station – Photo Credit: Getty Images

The future of NASA’s Landsat Next is in question, which includes a trio of satellites set to launch in 2031 for monitoring Earth’s dynamic landscapes.

Meanwhile, several climate satellites and instruments currently operational, such as orbital carbon observatories and deep-sea climate stations, face closures even though they remain fully functional.

Another mission facing uncertainty is the Nancy Grace Roman Space Telescope, scheduled for launch between 2026 and 2027, aimed at planetary exploration and investigating cosmic evolution.

This initiative is expected to be pivotal in understanding dark matter, dark energy, and answering fundamental questions about the universe.

Though Roman’s costs have escalated from an initial $2 billion (£1.6 billion) to over $3.2 billion (£2.5 billion), with 90% of the projected expenditure already incurred, the budget proposes reducing its development funding by $244 million (£133.9 million).

Ultimately, it remains unclear how the budget will be finalized as it awaits Congressional approval. Will these cuts devastate scientific progress, or usher in a new era of human exploration?

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Source: www.sciencefocus.com

Early Findings Indicate Elevated Risk of Colon Cancer in Long-Distance Runners

Researchers may have identified a potential connection between extreme endurance running and colorectal cancer, as nearly half of marathon and ultra-marathon participants have undergone screening.

Initial research assembled 100 long-distance runners aged 35-50 for colonoscopy, though these findings have not yet been peer-reviewed.

Close to 50% were found to have polyps (growths), with 15% diagnosed with advanced adenomas—growths that are likely to progress to cancer.

In contrast, recent studies indicate that only about 4.5 to 6 percent of adults in their late 40s from the general population have these advanced adenomas. However, it’s important to note that these studies included significantly larger sample sizes.

“I was quite concerned when I observed a group of ultra-marathon runners in their 30s diagnosed with stage 4, very advanced colorectal cancer,” said Dr. Timothy Cannon, who led the study at the Inova Schar Cancer Institute in Virginia. BBC Science Focus.

“They reported experiencing bleeding and convulsions post-race. At least one or two mentioned that they were told this was normal following their runs.”

Such symptoms can result from ischemic colitis, where blood flow is diverted from the colon to supply oxygen to the legs and other muscles during intense activity. This can lead to swelling and bleeding but typically resolves spontaneously.

Dr. Cannon speculated whether repeated cycles of damage and healing could create conditions conducive to cancer development.

Blood flow to the legs deprives the intestines of oxygen.

“There is currently no evidence that ischemic colitis directly causes cancer,” he stated. “However, it’s not difficult to imagine the potential outcomes. When numerous cells die and regenerate chaotically, there are ample chances for DNA replication errors.”

Alternative explanations exist as well. Endurance athletes are known to possess distinct gut microbiota compared to non-runners, and they often consume considerable amounts of ultra-processed foods, such as bottled energy drinks.

Dr. Cannon’s team is preparing to compare the gut bacteria of runners with and without adenomas to that of non-runners.

The findings were presented at the American Society of Clinical Oncology’s annual meeting, yet researchers cautioned that these are merely preliminary results, necessitating further investigation. They also highlighted that the screening study lacked a control group of non-runners.

“This leans more toward hypothesis than definitive answers,” Cannon remarked.

“I definitely don’t want people to walk away thinking exercise is harmful because it is beneficial overall. The inquiry is whether high levels of exercise could elevate the risk of colon cancer—and I believe they might.”

Read more:

  • Running slowly may be essential for a healthier, longer lifespan. Here’s why
  • What are the limits of human endurance?
  • The astonishing truth about how running can alter one’s perception of time

Source: www.sciencefocus.com

Revolutionary Quantum Funds Stored on Ultra-Cold ‘Debit Card’

Quantum Debit Card Ensures Financial Security

GlobalImages101/alamy

New quantum debit cards, which can hold unforgeable quantum funds, are constructed using extremely cooled atoms and light particles.

While standard banks often rely on the skill of counterfeiters to detect fake banknotes, quantum banks utilize the no-cloning theorem from physics, rendering counterfeiting impossible. This principle, which states that creating identical copies of quantum information is not feasible, led physicist Stephen Wiessner to propose a protocol in 1983 for generating secure currencies. Julian Laurat and his team at the Kastler Brossel Laboratory in France are actively implementing this groundbreaking concept in advanced experiments.

According to this protocol, banks create banknotes composed of quantum particles, possessing unique properties and existing in specific quantum states, thus ensuring protection against forgery through the no-cloning theorem. Laurat remarks that the protocol showcases an impressive feat of quantum cryptography, though it has not yet been put into practice for actual quantum fund storage.

The research team has made storage feasible by combining memory devices with hard drives. In their experiments, users interact with quantum systems that act as banks by exchanging photons. Each photon can be stored similarly to loading money onto a debit card.

The memory devices used by the team consist of hundreds of millions of cesium atoms, which researchers cool down to nearly absolute zero by bombarding them with lasers. At such extreme temperatures, light can precisely manipulate the quantum state of atoms, but Laurat notes that years were spent identifying the optimal cooling needed for atomic memory to serve as a quantum debit card. Through extensive testing, he and his colleagues demonstrated that users can retrieve photons from atoms without corrupting their states, as long as the process is not tampered with.

Christophe Simon from the University of Calgary emphasizes that the new experiment marks progress toward fully realizing quantum funding. However, the current quantum memory storage time of around six million seconds remains insufficient for practical application. “Another future step is to enhance portability. The long-term goal is to develop quantum memory that can be easily carried, particularly for Quantum Money applications. But we are not there yet,” he states.

The team is focused on extending storage durations, asserting that the protocol can be employed within quantum networks already being established in metropolitan areas across the globe. Additionally, cutting-edge quantum memory not only facilitates ultra-secure long-distance quantum communication but is also instrumental in connecting various quantum computers to more powerful systems.

Topics:

  • Quantum Computing/
  • Encryption

Source: www.newscientist.com

Webb Discovers Intricate Structures in Saturn’s Upper Atmosphere

Astronomers utilizing the NASA/ESA James Webb Space Telescope have identified a series of dark, bead-like star formations within Saturn’s ionosphere and stratosphere.

Detection of near-infrared emissions in Saturn’s ionosphere (left) reveals dark bead-like features embedded in bright auroras. In the stratosphere (right), below 500 km, an asymmetric star pattern extends toward the equator. Image credit: NASA/ESA/CSA/WEBB/STALLARD et al.

“This was the first opportunity for me to make such detailed near-infrared observations of Saturn’s aurora and upper atmosphere,” said the researcher.

“We anticipated seeing emissions across various levels.”

“Instead, we observed intricate patterns of beads and stars, which might be interconnected despite their considerable height separation and could relate to the iconic hexagon within Saturn’s clouds.”

“These features were entirely unforeseen and remain unexplained.”

The research team concentrated on detecting infrared emissions from charged molecular hydrogen, which plays a significant role in Saturn’s atmospheric dynamics, offering valuable insights into the chemical and physical processes at work.

Using Webb’s near-infrared spectrograph, scientists observed H3+ ions at an altitude of 600 km, 1,100 km above Saturn’s nominal surface, alongside lower stratospheric methane molecules.

Within the ionosphere’s electrically charged plasma, a series of dark bead-like features intermingled within bright aurora halos were detected.

These structures maintained stability for several hours but seemed to drift slowly over time.

In the stratosphere of Saturn, researchers identified asymmetric star-shaped features, dropping approximately 500 km.

This remarkable formation extended from Saturn’s North Pole down toward the equator.

Only four of the star’s six arms were visible, with two mysteriously absent, resulting in a biased pattern.

“Studying Saturn’s atmosphere has always posed challenges due to the faint emissions from that region,” remarked Professor Stallard.

“Webb’s remarkable sensitivity transforms our capacity to observe these atmospheric layers, unveiling a wholly different structural configuration than previously noted.”

The authors meticulously mapped the precise locations of features, overlaying data for the same Saturn area, discovering that the arms of the star seem to emanate from a point just above the hexagonal structure at the Stormcloud level.

This implies that the mechanisms driving the pattern could influence structures penetrating through Saturn’s atmosphere.

“We believe the dark beads arise from the intricate interactions between Saturn’s magnetosphere and its dynamic atmosphere, potentially providing new insights into the energy exchanges that fuel Saturn’s auroras,” stated Professor Stallard.

“The asymmetric star formations suggest previously unknown atmospheric processes functioning within Saturn’s stratosphere and are likely connected to the hexagonal storm pattern observed deeper in Saturn’s atmosphere.”

“Interestingly, the dark beads in the ionosphere seem to align with the arms of the strongest stars in the stratosphere, though it’s unclear whether this connection is genuine or merely coincidental.”

Both phenomena may have significant implications for our comprehension of atmospheric dynamics within the gas giant, although further investigation is needed to elucidate their underlying causes.

The team aspires for additional time to conduct follow-up observations of Saturn using Webb to explore further features.

As planets align approximately every 15 years, the structure can undergo dramatic changes as Saturn’s orientation shifts toward the Sun, moving the Northern Hemisphere into autumn.

“The necessity for follow-up Webb observations during this pivotal phase of Saturn’s seasonal transition is evident, as neither atmospheric layer can be examined using ground-based telescopes.” Paper published in the journal Geophysical Research Book.

The findings were also presented as a result this month at the EPSC-DPS2025 Joint Meeting in Helsinki, Finland.

____

Tom S. Stallard et al. 2025. JWST/NIRSPEC detects the complex structures of Saturn’s ionosphere and stratosphere. Geophysical Research Book 52 (17): E2025GL116491; doi: 10.1029/2025GL116491

Tom S. Stallard et al. 2025. Transformational observations of the ionosphere of the giant planet with JWST. EPSC Abstract 18: EPSC-DPS2025-817; doi: 10.5194/epsc-dps2025-1438

Source: www.sci.news

How Fat Storage Locations Impact Brain Function

Our brain activity and health is influenced by various bodily events

Cavallini James/BSIP/Getty Images

The impact of body fat on our movements, emotions, and even the likelihood of developing Alzheimer’s disease varies based on its location within the body.

While many studies emphasize abdominal fat due to its correlation with cognitive decline and heart disease, few have explored fat distribution in other regions, usually with limited participant numbers.

To broaden understanding, Qiu from the Hong Kong Polytechnic University and her team investigated the effects of fat in the arms, legs, torso, and around internal organs on brain health.

The research team analyzed body composition scans and Brain Imaging data of over 18,000 adults with an average age of 62 involved in the UK Biobank Project. After taking age and other factors into account, they associated excess fat in different body regions with specific brain changes.

For instance, higher fat levels in the arms and torso correlated with thinning in the sensorimotor cortex, which is involved in movement. Increased arm fat was also linked to reduced hippocampal volume, a crucial area for memory that is traditionally affected in Alzheimer’s disease, potentially explaining why arm fat is associated with a higher risk of neurodegenerative disorders.

The researchers found that excess leg fat correlated with diminished connectivity in the brain’s limbic network, which is responsible for emotion and reward processing. This may be due to the fact that fat in the lower body releases leptin, a hormone that regulates hunger, with higher leptin levels connected to reduced limbic connectivity.

Conversely, visceral fat (around internal organs) was the type most strongly linked to functional changes in the brain, uniquely associated with white matter degradation—a characteristic of Alzheimer’s disease—rather than its preservation.

This may arise from the fact that visceral fat produces more inflammatory substances compared to fat located elsewhere in the body, according to Sonia Anand from McMaster University in Canada, which can contribute to brain inflammation.

It remains unclear why arm fat appeared to have both protective and detrimental effects on the brain. “Observing such divergent impacts was intriguing,” noted Mikal Schneider Biary from Rutgers University, New Jersey. This complexity underscores the intricate relationship between body fat and brain health, she added.

The research only established correlations between body fat and brain function, so “we can’t infer any causal connections,” Biary cautions. Some brain changes may indeed influence the distribution of body fat. Moreover, the findings might not apply to the broader population, as there was a notable lack of diversity among participants.

Nevertheless, the study emphasizes that different types and locations of fat exert varying effects, according to Anand. This suggests that treatments focusing on reducing visceral fat could have a more significant impact on brain health than generalized weight loss approaches.

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Source: www.newscientist.com

Rising Atmospheric Hydrogen: A Potential Climate Concern

Hydrogen can indirectly warm the atmosphere

axa/esa

Hydrogen levels in the atmosphere have surged by 60% since the pre-industrial era, underscoring the significant influence of fossil fuel use on the Earth’s atmospheric makeup. While hydrogen itself isn’t a greenhouse gas, it contributes to warming indirectly through its interactions with other substances.

The research findings stem from the first comprehensive long-term observations of atmospheric hydrogen, which are derived from ice core data collected in Greenland in 2024. “Ice core records are incredible,” notes Alex Archibald from Cambridge University.

Being a small and lightweight molecule, hydrogen tends to escape into the atmosphere easily, often leaking from the ice core before it is analyzed in the lab.

To tackle this issue, John Patterson from the University of California, Irvine, and his team examined the ice core samples right after extraction. “We took our equipment out onto the ice. As soon as we extracted the samples, we cleaned and sealed them in a melted chamber for analysis,” he explains.

This approach enabled the researchers to establish a long-term record of atmospheric hydrogen stretching back 1,100 years, marking a significant improvement over previous records that reached only 100 years, largely based on observational data and snowfall analyses. “It’s quite an impressive feat logistically. We’re excited to share these findings,” remarks David Stevenson from the University of Edinburgh, UK.

The study discovered that hydrogen concentrations have risen from roughly 280 parts per billion in the early 19th century to around 530 parts per billion today. According to Patterson, this is not surprising given the rapid increase in fossil fuel usage since the pre-industrial period—when fossil fuels or biomass burn, hydrogen is released as a by-product.

Patterson and his team merged data from ice core records with modeling efforts to illustrate the fluctuations in hydrogen levels over the millennium. “Our data reveals changes in atmospheric composition, but the reasons behind these changes remain unclear,” says Patterson. “We aim to utilize biogeochemical models to investigate these variations.”

Ice cores can reveal historical hydrogen levels in the atmosphere

John Patterson

For instance, evidence from ice cores indicates that atmospheric hydrogen levels dipped by 16% during the so-called Little Ice Age, a cold period from the 16th to the 19th century. The decrease in wildfire emissions during this time does not completely account for the notable drop in hydrogen concentrations, according to Patterson. “This suggests that natural hydrogen biogeochemistry is adapting to climate change in ways we still don’t fully comprehend. This unexpected finding could be significant for future scenarios, indicating that atmospheric hydrogen levels might be more sensitive to climate fluctuations than previously believed,” Patterson cautions.

In the atmosphere, hydrogen competes with methane and engages with hydroxyl radicals, which play a crucial role in eliminating methane from the atmosphere, a potent greenhouse gas. “As hydrogen levels rise, the amount of hydroxyl available to react with methane decreases,” explains Patterson, potentially enhancing methane’s warming effect. “Currently, hydrogen constitutes about half of the total in the atmosphere, contributing approximately 2% to the overall anthropogenic warming effect according to our best estimates.”

Gaining a deeper understanding of the hydrogen cycle is essential to assess whether the widespread adoption of hydrogen fuels, as a transition away from fossil fuels, might lead to unanticipated consequences. For instance, a sudden spike in atmospheric hydrogen could magnify the warming impact of methane. Methane emissions have consistently risen since 2007, influenced by fossil fuel production, agriculture, and warming that releases stored methane from wetlands and permafrost.

“Methane is a significant factor causing us to hesitate in endorsing a hydrogen economy, as it inevitably leads to hydrogen leaks into the atmosphere,” emphasizes Archibald. “If hydrogen escapes into the atmosphere, it worsens the methane issue.”

It might spark discussion over the cautious use of hydrogen, especially if renewable energy cannot sufficiently replace fossil fuels, according to Archibald. Nonetheless, Patterson and other experts highlight that the warming effects from increased hydrogen use are expected to be minimal compared to the considerable warming impact of fossil fuels. “We don’t want to discourage people from pursuing hydrogen energy, as it’s a much cleaner option than its fossil fuel counterparts,” emphasizes Patterson.

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Source: www.newscientist.com

One Blood Sample Can Uncover 11 Years of Organ and System Health

Small Blood Samples Reveal Insights into Health

Momo Productions/Getty Images

A single blood test can unveil the biological ages of 11 distinct organs and systems in the body, potentially indicating disease risks in those areas.

“Our objective is to enhance care using one test that reflects not just the overall biological age, but identifies which system is primarily influencing it,” explains Raghav Sehgal from Yale University. “This way, individuals can receive tailored lifestyle or treatment recommendations based on their profiles.”

To evaluate an individual’s lifespan and health risks, biological age serves as an indicator of the rate at which their body ages, contrasting this with chronological age, according to Morgan Levine at Altos Labs in California. Researchers have designed an epigenetic watch to assess DNA methylation, which involves the addition or removal of chemical tags that toggle genes on and off.

While it’s convenient, its accuracy is questioned by Levine. Different organs and systems age at varied rates, heavily influenced by genetics and medical history, she highlights.

“There is a common belief that within an individual, organs and systems can be distinct.” Vadim Gladyshev from Harvard University, who did not partake in the research, notes. “Some brains may exhibit older characteristics, while kidneys may age differently compared to other organs.”

Thus, Sehgal, Levine, and their colleagues embarked on creating methylation tests that target aging states in various body parts. Initially, they assessed physical measurements, including blood tests, medical histories, and grip strength from around 7,500 individuals involved in two major research programs, namely the Health and Retirement Study—a database of U.S. residents over 50 and some U.S. families contributing DNA for genomic research.

Researchers searched for clear connections between age-related conditions, encompassing immune, inflammatory, hematological, musculoskeletal, hormonal, and metabolic systems along with five key organs linked to the heart, lungs, kidneys, liver, and brain. They then correlated these findings with DNA methylation patterns, trained computer models to recognize those patterns, calculated the biological age of each system, and generated an overall biological age.

After training their models, the team tested it on blood samples from another 8,125 individuals whose data originated from four other studies. They discovered, for instance, that the model’s heart score could predict heart disease, brain scores were associated with cognitive decline, and musculoskeletal scores indicated whether individuals were likely to have arthritis-like conditions.

Comparing their findings with established epigenetic clocks, the researchers noted that organ-specific scores demonstrated strong accuracy, with many yielding excellent results. “It’s quite remarkable that a single factor measured through a blood test can effectively estimate aging across multiple systems,” remarks Levine.

Daniel Belsky from Columbia University in New York describes the epigenetic clock as representing “significant” advancements in aging research. “This marks the initial foray into developing interpretable measures of biological aging that allow for simultaneous analysis of multiple systems, guiding back to specific tissues or organs,” he explains. “It provides a pathway for reverse-engineering from aggregate measurements to pinpoint where health issues may emerge.”

Nonetheless, he cautions that this method might deviate from the overarching objectives of the field. “The essence of genetic science and the potential of aging biology resides in perceiving humans as coherent systems where we seek to identify the weakest links to bolster and avert failures,” Belsky asserts. “Maintaining this integrated perspective is crucial.”

Crucially, Levine clarifies that this test is not intended for diagnostic purposes but for risk assessment. “All assessments, including those in our studies, aim to provide estimates and insights into the inner workings of our bodies,” she emphasizes. “Future research should yield stronger and more precise estimates of aging by integrating various approaches, capturing the complexity and diversity of the aging process.”

Gladyshev envisions that this research could lead to personalized disease prevention strategies. “This represents the core implication of this series of studies,” Belsky adds, while emphasizing the need for further investigation. “We’re not quite there yet.”

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Source: www.newscientist.com