Alan Turing Institute in the UK commences consultation on potential lay offs due to AI advancements

The National Institute for Artificial Intelligence and Data Science in Britain has initiated a consultation process that may result in the redundancy of 440 employees.

In a memo sent to staff this month, the Alan Turing Institute announced an update on its new strategy, which involves focusing on a smaller number of projects.

Addressed to “affected employees,” the letter mentioned that government-backed labs might have to reduce their workforce. Unofficial estimates suggest that the memo could have been sent to about 140 individuals.

The institute collaborates with universities, private companies, and government agencies on 111 active projects. An internal document states that they will need to scale back their involvement in some projects.

Last year, the institute introduced a new strategy called “Turing 2.0,” with a focus on health, environment, defense, and security. However, due to lower core funding, they are considering restructuring and potentially closing certain projects.

The institute is evaluating which projects align with their new strategy and could lead to staff reductions. They aim to minimize layoffs and will involve employee representatives in the decision-making process.

Dr. Jean Innes, the institute’s CEO, mentioned that they are entering a new ambitious phase to address societal challenges using technology.

Named after the renowned mathematician, the institute was initially focused on data science before including AI in its mission in 2017. Its objectives include conducting top-notch research to tackle global issues and fostering informed discussions about AI.

With upcoming government announcements on technology, the institute is gearing up for potential changes. This includes launching an “AI Action Plan” led by Technology Entrepreneur Matt Clifford, focusing on economic growth and public service enhancement.

Additionally, there are plans to establish a legally binding AI model testing agreement with tech companies, separate the UK AI Safety Institute from the Turing Institute, and introduce a consultation on the proposed AI bill.

Source: www.theguardian.com

Scientists believe that Earth’s recent discovery of a new mini-moon indicates significant potential for space mining.

Our planet’s new small satellite, 2024 PT5, arrived in Earth’s orbit on September 29, 2024.

2024 PT5 is scheduled to capture a temporary flyby from September 29th to November 25th in 2024. Image credit: University of Colorado.

2024 PT5 was discovered by the Asteroid Earth Impact Final Warning System in Sutherland, South Africa on August 7, 2024.

This near-Earth asteroid is about 10 meters (33 feet) in diameter and follows an orbit similar to that of 2022 NX1.

2024 PT5 will become a mini-Earth satellite on September 29 and return to heliocentric orbit 56.6 days later on November 25.

“Near-Earth objects like this offer a glimpse into the formation process of the solar system,” said astrophysicist Dr. Nico Cappellutti. University of Miami.

“Most asteroids in our solar system are rocky remnants left over from the formation of our solar system.”

2024 PT5 is part of Arjuna, an asteroid belt made up of space rocks that follow an orbit around the sun very similar to Earth’s orbit.

“So sometimes they can remain temporarily trapped in our gravitational field,” Dr. Cappellutti said.

“Bringing them this close is a fascinating opportunity.”

“The asteroid, the size of a school bus, is too faint and small to be seen with the naked eye or with amateur telescopes, but its two-month stay around Earth has reinforced our intense interest in space rocks. It helps maintain.”

Two years ago, in what was called the first test of the planetary defense system, NASA crashed a spacecraft into the giant space rock Dimorphos, which could change direction if the asteroid was on a collision course with Earth. proved something.

Private companies also want to send spacecraft to asteroids in hopes of mining the precious metals they contain.

“Asteroids are classified based on their orbits and their contents,” said Dr. Bertrand Dano, also from the University of Miami.

“Some are made entirely of stone, while others contain high concentrations of rare metals, such as platinum and gold for electronics, nickel and cobalt for catalysts and fuel cell technology, and, of course, iron.”

“Mining asteroids is not far off. There are currently millions of asteroids in our solar system, about 2 million of which are larger than 1 km.”

“The resources it contains are a new dream for El Dorado, and there are several companies currently betting on it.”

“Recent missions to rendezvous with, orbit and land on asteroids have proven that space mining may be only a matter of time.”

“However, proceeding with asteroid mining will require huge investments, from the mining equipment that needs to operate in a vacuum to the technology needed to transport the extracted minerals to Earth.”

“And then there’s the spacecraft itself. A dedicated ship that would travel to an asteroid for the purpose of extracting minerals from the asteroid would probably be a robotic ship.”

“A trip to Mars would take about eight months under the best conditions. The space and equipment needed to support life would be put to good use as storage for backup equipment and resources.”

“Because it takes a lot of energy to leave Earth’s gravity, mining missions are better launched from space or from low-gravity bodies such as the Moon, Mars, or Titan, one of Saturn’s natural moons. Sho.”

“Returning to Earth is relatively easy, but dangerous for the material. It would be a shame if all the prizes disappeared. Refining will take place in space, and purified products can be shipped regularly. As far as I know, no one is thinking that far.”

“Yet, asteroid mining could have a 100-fold or more return.”

“Mining platinum or gold from an asteroid and returning it could make you a trillionaire overnight, potentially upending entire economies, trade and markets.”

“Astrophysicist Neil deGrasse Tyson once said, ‘The first billionaire in history was the one who exploited the natural resources of asteroids.'”

Source: www.sci.news

Pharmacological potential discovered in toxins found in crustacean venom from Mayan underwater caves

Xibalbanus turmensisThe poisonous remipede, found in the caves of Antiarin on the Yucatan Peninsula, is the only crustacean for which a venom system has been described.

Xibalbanus turmensis. Image credit: Pinheiro-Junior others., doi: 10.1186/s12915-024-01955-5.

“Poisonous animals inject toxic compounds into other organisms primarily for self-defense or predation,” said Dr. Björn von Roymont, a researcher at Goethe University Frankfurt, and his colleagues.

“Many venoms are composed of proteins that have evolved to modulate various physiological functions in the target organism.”

“Studying these biological activities could lead to pharmacological or agrochemical applications.”

“The majority of thoroughly studied venoms and venomous proteins originate from iconic terrestrial groups, primarily snakes, spiders, scorpions, and insects,” the researchers said.

“Research attention to marine life has been limited, with only a few fish and invertebrates being better studied, such as sea anemones, jellyfish, cone snails, cephalopods, polychaetes, and more recently nemertes.”

“Venoms and their toxic proteins have evolved independently in different animal lineages, so the study of new lineages provides an opportunity to identify novel toxic compounds with interesting biological activities, on the one hand, and generally convergent proteins on the other hand. It provides an opportunity to improve our understanding of the evolution of functional traits.”

In their study, the researchers investigated the biological activity of peptides found in crustacean venom. Xibalbanus turmensis.

This underwater cave-dwelling crustacean belongs to the following classes: Remipediafirst described in the 1980s and currently consists of 28 extant species.

Xibalbanus turmensis They live in cenotes, underwater caves in Mexico's Yucatan Peninsula,” the scientists said.

“Cave dwellers directly inject the venom produced by their venom glands into their prey.”

“This toxin contains a variety of components, including a new type of peptide named cibalbin after the crustacean producer.”

“Some of these sibalbins contain characteristic structural elements that are well known to other toxins, especially those produced by spiders. Some amino acids (cysteine) in the peptide are tied together like a knot. are connected to each other in such a way that they form a structure.

“This makes the peptide more resistant to enzymes, heat, and extreme pH values.”

“Such knots often act as neurotoxins, interacting with ion channels to paralyze prey. This effect has also been proposed for some cibalbins.”

This study shows that all sibalbin peptides tested by the team, particularly Xib1, Xib2, and Xib13, effectively inhibit potassium channels in mammalian systems.

“This inhibition is very important when developing drugs to treat a variety of neurological diseases, including epilepsy,” Dr. von Roymont said.

“Xib1 and Xib13 also exhibit the ability to inhibit voltage-gated sodium channels, such as those found in neurons and cardiomyocytes.”

“Furthermore, in higher mammalian sensory neurons, the two peptides can activate two proteins involved in signal transduction: the kinases PKA-II and ERK1/2.”

“The latter suggests that they are involved in pain sensitization, opening the door to new approaches in pain treatment.”

of the team findings Published in a magazine BMC biology.

_____

EL Pinheiro – Junior others. 2024. Xibalbin mutants divergently evolved from remipede toxin inhibit potassium channels and activate PKA-II and Erk1/2 signaling. BMC biol 22, 164; doi: 10.1186/s12915-024-01955-5

Source: www.sci.news

One tiny particle has the potential to alter our understanding of gravity

Gravity is one of the four fundamental forces that bind matter in the universe. The other three forces (electromagnetic, weak nuclear, and strong nuclear) are explained through the exchange of force-carrying elementary particles, leading theorists to believe there is a similar quantum explanation for gravity.

The force carriers for the electromagnetic force are photons, while the weak nuclear force has W-, W+, and Z0 bosons as force carriers, and the strong nuclear force has eight types of gluons. On the other hand, the hypothetical carrier of gravitational force is known as the graviton.



The properties of the graviton are deducible in quantum theory. The amount of energy required to summon a force-carrying particle from the vacuum determines how quickly it must be recovered. Since gravity has an infinite range and does not require energy to create a graviton, the mass of the graviton must be zero.

Additionally, gravitons are expected to have a spin of 2, as only spin 2 particles interact with all matter, which is characteristic of universal gravity. This is in contrast to quarks and leptons, which have a spin of 1/2, and the non-gravitational force carriers, which have a spin of 1.

While gravity may not be fully explained by the exchange of gravitons, most physicists believe it can be quantized. String theory offers a potential framework where fundamental particles are envisioned as vibrations of mass-energy strings, with each vibrating string having the properties of a graviton.

However, string theory faces challenges due to its complexity and inability to make testable predictions. Detecting gravitons is difficult due to the extremely weak nature of gravity and the rare interactions gravitons have with matter.

Despite the challenges in detecting gravitons, recent advancements in experimental exploration, such as the discovery of spin-2 particle properties in a liquid analogue system, provide hope for a better understanding of gravitons and the eventual unification of fundamental forces into a single theory.

About our experts

Tony Rothman: A theoretical physicist who has taught at Princeton and Harvard Universities, he has published non-fiction and fiction novels and written various stage plays outside of his academic career. He has contributed to publications like Physics Basics, European Journal of Physics, and Astrophysics and Space Sciences.

Source: www.sciencefocus.com

New findings suggest water may exist on Mars – here are the potential locations.

NASA's Mars Exploration Program includes two active rovers and three active orbiters. Concept studies for future Mars orbiter missions have begun.

Water on Mars may be lurking beneath or even above the planet’s surface.

NASA/JPL/USGS

Mars isn’t as dry as it seems. Billions of years ago, oceans and rivers of liquid water rippled across its surface, but now it appears that all of that liquid has disappeared, leaving behind a dusty barren landscape. But as we explore Mars with probes, landers, rovers, and even distant telescopic images, more and more traces of water are popping up.

Each hint fascinates researchers about how important water is to life and how it could aid future exploration. Water has now been found in various forms all over Mars. Here are five places where water has been found.

1. Buried underground

The InSight lander, visualized here, recently discovered new potential water reservoirs on Mars.

NASA/JPL-California Institute of Technology

Just beneath Mars’ dry surface lies an icy wonderland. These deposits are insulated by an overlying layer of dust, but erosion or meteorite impacts could expose them to the watchful eye of Mars orbiters. A single icy deposit recently identified using data from the Mars Express spacecraft appears to contain enough water to cover the entire Martian surface with an ocean 1.5 to 2.7 meters deep.

It’s not just ice buried under the orange sand. There’s a controversial theory that there’s a huge lake beneath Earth’s Antarctic pole. It could just be wet silt or volcanic rock. But… New Research Using data from the InSight lander, researchers have uncovered the possibility of another reservoir of water near the Martian equator. InSight found this water, buried 11.5 to 20 kilometers underground, by sensing Martian earthquakes and measuring the speed at which seismic waves travel. The results revealed that the rocks through which the earthquakes travel appear to be saturated with water.

2. Frost the pole

Frost in a crater on the North Plains of Mars

NASA/JPL-Caltech/University of Arizona

Reaching buried water on Mars will be difficult. For future explorers, the more promising reservoirs are probably exposed on the surface. Mars has ice caps at both poles, just like Earth’s, and we’ve known about them for decades. Many of Mars’ craters also contain small ice sheets inside them, the only places on the Martian surface cold enough to hold ice.

However, at higher latitudes on Mars, the air is cooler and more moist, and temporary frosts can occur. On frigid Martian mornings, volcano peaks are also covered in frost, likely caused by water vapor in the atmosphere freezing.

3. Floating in the atmosphere

www.newscientist.com

Potential for a “liquid water ocean” beneath the surface of Mars

Using new data about the Martian crust collected by NASA’s InSight spacecraft, geophysicists from the University of California, San Diego and the University of California, Berkeley estimate that groundwater could cover the entire planet to a depth of one to two kilometers. Groundwater exists in tiny cracks and pores in rocks in the mid-crust, 11.5 to 20 kilometers below the surface.

A cross section of NASA’s InSight lander and the data it collected. Image courtesy of James Tuttle Keane / Aaron Rodriquez.

“Liquid water existed at least occasionally in Martian rivers, lakes, oceans, and aquifers during the Noachian and Hesperian periods more than 3 billion years ago,” said Dr Vashan Wright of the Scripps Institution of Oceanography at the University of California, San Diego, and his colleagues.

“During this time, Mars lost most of its atmosphere and therefore the ability to support liquid water on its surface for any sustained period of time.”

“Ancient surface water may have been incorporated into minerals, buried as ice, trapped as liquid in deep aquifers, or lost to space.”

For the study, Dr Wright and his colleagues used data collected by InSight during its four-year mission, which ends in 2022.

The lander collected information from the surface directly beneath it about variables such as the speed of Mars’ seismic waves, which allowed scientists to infer what materials exist beneath the surface.

The data was fed into a model based on mathematical theories of rock physics.

Based on this data, the researchers determined that the presence of liquid water in the Earth’s crust was the most plausible explanation.

“If we prove that there is a large reservoir of liquid water, it could give us insight into what the climate was or could be like at that time,” said Professor Michael Manga of the University of California, Berkeley.

“And water is essential for life as we know it. I don’t see why underground reservoirs wouldn’t be habitable environments. On Earth they certainly are. There is life in deep mines, there is life at the bottom of the ocean.”

“We still don’t have evidence of life on Mars, but we’ve identified places that could, at least in principle, support life.”

“A wealth of evidence, including rivers, deltas, lake deposits, and hydrologically altered rocks, supports the hypothesis that water once flowed on the planet’s surface.”

“But that wet period ended more than 3 billion years ago, when Mars lost its atmosphere.”

“Planetary scientists on Earth have sent many probes and landers to Mars to learn what happened to the Martian water (water frozen in the Martian polar ice caps does not explain the whole story), when this happened, and whether life exists or ever existed on Mars,” the authors said.

“The new findings indicate that much of the water has seeped into the crust rather than escaping into space.”

“The new paper analyzes the deeper crust and concludes that the available data are best explained by a water-saturated mid-crust beneath the InSight location.”

“Assuming the crust is similar across the planet, this mid-crustal zone should contain more water than would have filled the hypothetical ancient Martian ocean.”

of Survey results Appears in Proceedings of the National Academy of Sciences.

_____

Vashan Wright others2024. Liquid water exists in the central crust of Mars. PNAS 121 (35): e2409983121; doi: 10.1073/pnas.2409983121

Source: www.sci.news

Potential Ocean’s Worth of Water Likely Hidden Beneath Mars’ Surface, Study Finds

Mars A recent study indicates that the Earth may be hiding a global ocean beneath its surface, with cracks in rocks potentially holding enough water to form it.

The report, released on Monday, highlights NASA’s Mars rover InSight. To date, more than 1,300 earthquakes have been detected on Mars. This study was closed two years ago.

Scientists believe that the water lies about seven to 12 miles (11.5 to 20 kilometers) deep in Mars’ crust, possibly originating from the planet’s ancient surface water sources such as rivers, lakes, and oceans billions of years ago, according to Vashan Wright, the lead scientist at the Scripps Institution of Oceanography at the University of California, San Diego.

Despite the presence of water inside Mars, Wright noted that it does not necessarily mean that life exists there.

“However, our findings suggest the possibility of habitable environments,” he mentioned in an email.

The research team combined computer simulations with InSight data, including earthquake speeds, to suggest that groundwater is the most likely explanation. These results were published in the Proceedings of the National Academy of Sciences on Monday.

Wright remarked that if InSight’s observations near the equator of Mars at Elysium Planitia are representative of the entire planet, there could be enough groundwater to fill a terrestrial ocean approximately a mile (1 to 2 kilometers) deep.

Tools like drills will be required to verify the presence of water and search for signs of microbial life.

Despite the InSight lander no longer being in operation, scientists are still analyzing the data collected between 2018 and 2022 to gain more insights into Mars’ interior.

Over 3 billion years ago, Mars was mostly covered in water, but due to the thinning of its atmosphere, it lost its surface water, becoming the dry and dusty world we see today. It is believed by scientists that the ancient water either escaped into space or remains hidden underground.

Source: www.nbcnews.com

Is Elon Musk alienating potential Tesla customers with his rhetoric? | Automotive industry

pictureRon Musk has long been interested in right-wing politics and has enjoyed portraying himself as a contrarian showman. However, his recent political affiliations have raised doubts about Tesla, the electric-car giant he founded. How much further can he push before customers start abandoning his product?

A German pharmacy chain, Rothmann, was among the first to speak out this week. The family business announced that it would not expand its fleet of 34 Tesla cars after Musk publicly supported Donald Trump for US president.

Rothmann’s spokesperson, Raul Rothman, wrote, “Mr. Trump has consistently denied climate change, which contradicts Tesla’s mission to protect the environment by producing electric vehicles.”

Musk’s support for Trump was followed by controversial posts about far-right riots in the UK. He made remarks like “Civil war is inevitable,” which sparked criticism from politicians across the spectrum. Musk engaged with far-right figures, raising concerns among some consumers.

Some Tesla owners are now reevaluating their choice of vehicle due to Musk’s recent behavior.

Given the divisive nature of Mr. Musk’s comments and his apparent enjoyment of creating discord, we have decided to discontinue our relationship with Tesla.”

Tesla has been reached out to for comment.

In online forums, Tesla owners debate the impact of Musk’s politics on the brand. Some have created bumper stickers like “I bought this before I knew Elon was crazy.”

David Bach, a strategy and political economy professor at IMD, noted that Musk’s recent behavior sets him apart from other CEOs. Musk’s actions have garnered mixed reactions, especially in the UK.

Tesla’s sales in the UK account for a small portion of its global business. Musk’s involvement in US politics, particularly with Trump, could have significant repercussions for Tesla.

Despite Musk’s polarizing comments, some consumers still support Tesla. However, there are concerns about the potential impact on business.

Musk’s actions have already affected X and could impact SpaceX as well. Some industry insiders believe that Musk’s current path could eventually lead to a decline in Tesla’s sales.

Source: www.theguardian.com

Black holes that have the potential to outlast the universe

Black holes have the ability to die, but this process happens very slowly and in a rather normal manner.

Despite appearing empty, space is not entirely devoid of mass or energy. Within this space, there exist “quantum fields” that give definition to mass and energy. These fields do not necessarily have zero energy, allowing for the creation of pairs of “virtual particles” (typically particle and antiparticle pairs) that quickly eliminate each other.


Another common explanation is that near a black hole, one of these particles may vanish inside the black hole while the other escapes as “Hawking radiation.”

In order to maintain the total energy of a black hole, incoming particles must possess “negative energy” (hence “negative mass”) while escaping particles must have positive energy.

Hawking radiation is a result of gravity’s impact on space-time. Quantum fields within empty space adhere to the Heisenberg uncertainty principle, limiting our understanding of the energy of a quantum field or the duration for which we can attribute a specific energy to it.

Since gravitational fields influence the curvature of space-time and the flow of time in a given area, regions of space-time with varying gravitational curvatures struggle to agree on the energy of the quantum field.

The variance in vacuum energy within different points of a black hole’s gravitational field creates what are known as “virtual particles.”

As positive energy escapes from a black hole, the mass and energy of the black hole gradually diminish, causing a black hole that is not actively attracting new material to gradually shrink and ultimately vanish.

However, this process occurs over massive time scales. For instance, a black hole with the mass of the sun would take 1064 years to evaporate, far surpassing the age of the universe at 10 years old.

This article endeavors to answer Catrin Phelps of Winchester’s question, “Can black holes ever die?”

If you have any further inquiries, please direct them to the email address provided below. For additional information: or get in touch with us via Facebook, Twitter, or Instagram (please include your name and location).

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Source: www.sciencefocus.com

Potential for Creating Life on Mars with Reflective Iron Rods

Terraforming Mars would make it more similar to Earth, creating an environment capable of supporting life as we know it.

Detlef van Ravensweig/Science Photo Library

Releasing iron rods the size of glitter particles into the Martian atmosphere could raise the planet's temperature enough to melt water and support microbial life.

Making the Red Planet's surface habitable for Earth-like life – a process known as “terraforming” – will be a complex one, but a key part of it will be raising the surface temperature above the current median freezing point of -65°C (-85°F).

Some have suggested placing mirrors on the Martian surface or pumping methane into the atmosphere, but these ideas are difficult to implement because the necessary raw materials would need to be shipped from Earth.

now, Edwin Kite Researchers at the University of Chicago in Illinois found that a relatively tiny dust cloud (about 9 micrometers long and 160 nanometers wide) made from iron or aluminum rods mined from Martian rocks could warm Mars by about 30 degrees Celsius over the course of a few months to more than a decade, depending on how quickly the particles are released.

These rods, each about 9 micrometers long and 160 nanometers wide, are carried by winds from the surface into Mars' upper atmosphere, where they will remain for about 10 years, trapping heat from the surface and transmitting sunlight.

Kite and his colleagues modeled how the rods respond to light and fed that information into climate simulations, which showed that the increased temperature and pressure would be enough to support liquid water and possibly oxygen-producing bacteria in parts of Mars.

They also found that to achieve this warming, it would be enough to release the fuel rods at a rate fast enough to power about 30 garden sprinklers — a total of 700,000 cubic meters of metal per year, or about 1% of Earth's metal production.

“When we did the math, we found that the amount of man-made dust we needed would be surprisingly small — much less than we would need to create the same amount of warming with man-made greenhouse gases,” Kyte says.

While mining the Martian surface would still be difficult, Kite says this would be 5,000 times more efficient than any warming method proposed so far.

One of the big uncertainties in the simulations is how the tiny bars interact with water in the Martian atmosphere, which could have unexpected effects such as causing the water to collect around the dust and rain down back to the surface, reducing global warming.

It's an intriguing idea that might work if the particles remain in the atmosphere long enough, he said. Manoj Joshi researcher at the University of East Anglia in the U.K. But even if the amount of metal needed is small, he says it would still be an enormous amount of work to produce.

Joshi said there are also ethical questions about whether it's OK to alter the atmosphere of another planet: “Mars is so unexplored and we don't know much about it. Is it OK to alter a planet in this way?”

topic:

Source: www.newscientist.com

The Big 7 tech companies are questioning the potential of the AI boom – What’s driving the doubt? | Artificial Intelligence (AI)

It’s been a tough week for the Grand St. Seven, a group of technology stocks that have played a leading role in the U.S. stock market, buoyed by investor excitement about breakthroughs in artificial intelligence.

Last year, Microsoft, Amazon, Apple, chipmaker Nvidia, Google parent Alphabet, Facebook owner Meta and Elon Musk’s Tesla accounted for half of the S&P 500’s gains. But doubts about returns on AI investments, mixed quarterly earnings, investor attention shifting elsewhere and weak U.S. economic data have hurt the group over the past month.

Things came to a head this week when the shares of the seven companies entered a correction, with their combined share prices now down more than 10% from their peak on July 10.

Here we answer some questions about Seven and the AI boom.


Why did AI stocks fall?

First, there are concerns that the huge investments being made by Microsoft, Google and others in AI will pay off. These have been growing in recent months. Goldman Sachs analysts The memo was published In June, the Wall Street bank released a report titled “Gen AI: Too Much Spending, Too Little Reward?” which asked whether $1 trillion in investment in AI over the next few years “will ever pay off,” while an analysis by Sequoia Capital, an early investor in ChatGPT developer OpenAI, estimated that tech companies would need $600 billion in rewards to recoup their AI investments.

Gino said “The Magnificent Seven” is also hit by these concerns.

“There are clearly concerns about the return on the AI investments that they’re making,” he said, adding that big tech companies have “done a good job explaining” their AI strategies, at least in their most recent financial results.

Another factor at play is investor hope that the Federal Reserve, the U.S. central bank, may cut interest rates as soon as next month. The prospect of lower borrowing costs has boosted investors’ support for companies that could benefit, such as small businesses, banks and real estate companies. This is an example of “sector rotation,” in which investors move money between different parts of the stock market.

Concerns about the Big 7 are affecting the S&P 500, given that a small number of tech stocks make up much of the index’s value.

“Given the growing concentration of this group within U.S. stocks, this will have broader implications,” said Henry Allen, macro strategist at Deutsche Bank AG.Concerns about a weakening U.S. economy also hit global stock markets on Friday.


What happened to tech stocks this week?

As of Friday morning, the seven stocks were down 11.8% from last month’s record highs, but had been dipping in and out of correction territory — a drop of 10% or more from a recent high — in recent weeks amid growing doubts.

Quarterly earnings this week were mixed. Microsoft’s cloud-computing division, which plays a key role in helping companies train and run AI models, reported weaker-than-expected growth. Amazon, the other cloud-computing giant, also disappointed, as growth in its cloud business was offset by increased spending on AI-related infrastructure like data centers and chips.

But shares of Meta, the owner of advertising-dependent Facebook and Instagram, rose on Thursday as the company’s strong revenue growth offset promises of heavy investment in AI. Apple’s sales also beat expectations on Thursday.

“Expectations for the so-called ‘great seven’ group have perhaps become too high,” Dan Coatsworth, an analyst at investment platform AJ Bell, said in a note this week. “These companies’ success puts them out of reach in the eyes of investors, and any shortfall in greatness leaves them open to harsh criticism.”

A general perception that tech stocks may be overvalued is also playing a role: “Valuations have reached 20-year highs and they needed to come down and take a pause to digest some of the gains of the past 18 months,” says Angelo Gino, a technology analyst at CFRA Research.

The Financial Times reported on Friday that hedge fund Elliott Management said in a note to investors that AI is “overvalued” and that Nvidia, which has been a big beneficiary of the AI boom, is in a “bubble.”


Can we expect to see further advances in AI over the next 12 months?

Further breakthroughs are almost certain, which may reassure investors. The biggest players in the field have a clear roadmap, with the next generation of frontier models already underway to train, and new records are being set almost every month. Last week, Alphabet Inc.’s Google DeepMind announced that its system had set a new record at the International Mathematical Olympiad, a high school-level math competition. The announcement has observers wondering whether the company will be able to tackle long-unsolved problems in the near future.

The question for labs is whether these breakthroughs will generate enough revenue to cover the rapidly growing costs of achieving them: The cost of training cutting-edge AI has increased tenfold every year since the AI boom really began, raising questions about how even well-funded companies such as OpenAI, the Microsoft-backed startup behind ChatGPT, will cover those costs in the long run.


Is generative AI already benefiting the companies that use it?

In many companies, the most successful uses of generative AI (the term for AI tools that can create plausible text, voice, and images from simple prompts) have come from the bottom up: people who have effectively used tools like Microsoft’s Copilot or Anthropic’s Claude to figure out how to work more efficiently, or even eliminate time-consuming tasks from their day entirely. But at the enterprise level, clear success stories are few and far between. Whereas Nvidia got rich selling shovels in the gold rush, the best story from an AI user is Klarna, the buy now, pay later company, which announced in February that its OpenAI-powered assistant can: Resolved two-thirds of customer service requests In the first month.

Dario Maisto, a senior analyst at Forrester, said a lack of economically beneficial uses for generative AI is hindering investment.

“The challenge remains to translate this technology into real, tangible economic benefits,” he said.

Source: www.theguardian.com

Google claims that AI has the potential to enhance nearly 66% of jobs in the UK

Google states that nearly 66% of jobs in the UK could be “augmented” by AI, with only a small percentage of jobs at risk of complete elimination. The company emphasizes the importance of supporting workers to utilize AI technology to improve efficiency rather than fearing job loss.

Debbie Weinstein, managing director of Google UK, highlights the low adoption rate of AI tools in workplaces and emphasizes the need for people to feel confident and capable in using these technologies to unlock their full potential.

Research commissioned by Google from think tank Public First reveals that 61% of UK jobs will be significantly impacted by AI, with only 31% remaining unaffected by the technology. Certain industries like social care, transportation, and accommodation and food services, which involve complex physical labor, are less likely to be automated.

Public First estimates that only a few jobs will become obsolete due to AI, with the majority of jobs expected to be enhanced instead. Google has partnered with various organizations to introduce AI technologies in a way that enhances worker capabilities without replacing them.

The government is also supporting the adoption of AI across the economy to drive growth and provide new opportunities for workers. Minister for AI, Feriel Clarke MP, emphasizes the importance of AI skills training to help workers thrive in the changing job market.

Public First predicts that full adoption of AI over the next six years could bring significant economic benefits to the UK, with an annual growth rate of 2.6% driven by technology alone. Google claims that using generative AI could save the average UK worker 100 hours a year, marking the biggest improvement in productivity since the introduction of Google Search.

Despite some controversies surrounding AI tools like Gemini AI, Google continues to invest in AI products and features to enhance user experiences. The company aims to revamp Google search with AI Briefs, although this has faced criticism for potentially reducing traffic to publisher sites.

Source: www.theguardian.com

Potential Discovery: Understanding How the Placebo Effect Alleviates Pain

A slide showing part of a mouse brain

Stu Gray / Alamy

A newly identified brain pathway in mice may explain why placebos, or interventions that should have no therapeutic effect, can relieve pain, and the development of drugs that target this pathway could lead to safer alternatives to painkillers such as opioids.

If someone unknowingly takes a sugar pill instead of a painkiller, they still feel better. The placebo effect is a well-known phenomenon in which people's expectations reduce symptoms even in the absence of an effective treatment. “Our brain can solve the pain problem on its own, based on the expectation that a drug or treatment might work,” says Dr. Gregory Scherer At the University of North Carolina at Chapel Hill.

To understand how the brain does this, Scherer and his colleagues recreated the placebo effect in 10 mice using a cage with two chambers: one with a blazingly hot floor and the other with no floor. After three days, the mice learned to associate the second chamber with pain relief.

The researchers then injected molecules into the animals' brains that caused active neurons to light up when viewed under a microscope, and then returned the animals to their cages, but this time they heated both floors.

Although the two chambers were now equally hot, the mice still preferred the second chamber and showed less symptoms of pain, such as licking their paws, while they were there. They also showed more neuronal activity in the cingulate cortex, a brain region involved in processing pain, compared with nine mice that had not been conditioned to associate the second chamber with pain relief.

Further experiments revealed pathways connecting these pain-processing neurons to cells in the pontine nuclei and cerebellum, two brain regions not previously known to play a role in pain relief.

To confirm that this circuit relieved pain, the researchers used a technique called optogenetics, which switches cells on and off with light. This allowed them to activate the newly discovered neural pathway in another group of mice that were placed on a hot floor. On average, these mice took three times longer to lick their paws than mice that didn't have the circuit activated, indicating that they felt less pain.

If this neural pathway explains the placebo effect, “it could open up new strategies for drug development,” he said. Luana Colocca “If we had a drug that could activate the placebo effect, it would be an excellent strategy for pain management,” said University of Maryland researcher David L. Schneider, who was not involved in the study.

“An obvious caveat is that the placebo experience in humans is clearly much more complex. [than in animals]”The pain pathways are very similar to ours,” Scherer said, but because rodents and humans have very similar pain pathways, he believes these findings also apply to humans.

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Source: www.newscientist.com

The Evolution of Human Brains: The Potential Consequences for Our Future

No one doubts that Albert Einstein had a brilliant mind, but the Nobel Prize winner famous for his theories of special and general relativity wasn’t blessed with a big brain. “Jeremy DeSilva at Dartmouth College in New Hampshire.”

This seems surprising. Big brains are a defining feature of human anatomy, something we are proud of. Other species may be faster or stronger, but we thrive using the ingenuity that comes from our big brains. At least, that’s what we tell ourselves. Einstein’s brain suggests that the story is not so simple. And recent fossil discoveries bear this out. In the past two decades, we’ve learned that small-brained hominin species persisted on Earth long after species with larger brains emerged. Moreover, there is growing evidence that they were behaviorally sophisticated. For example, some of them made complex stone tools that could only have been made by humans with language.

These findings turn questions about the evolution of the human brain upside down: “Why would large brains be selected for when humans with small brains can survive in nature?” says DeSilva. Nervous tissue consumes a lot of energy, so large brains must have undoubtedly provided an advantage to the few species that evolved them. But what was the benefit?

The answer to this mystery is beginning to emerge. It appears that brain expansion began as an evolutionary accident that then led to changes that accelerated brain growth. Amazingly, the changes that drove this expansion also explain the recent 10 percent shrinkage of the human brain. What’s more, this suggests that our brains could shrink even further, potentially causing our demise.

There’s no denying that…

Source: www.newscientist.com

Why the potential hacking of satellites in orbit is a major cause for concern

Picture this: a hacker sitting at their laptop, frantically typing code as it flashes across the screen. Suddenly, they successfully hack into a satellite. Sounds like a scene from a James Bond movie, doesn’t it? But in reality, it poses a real threat.

Contrary to the dramatic portrayal in movies, hacking a satellite is much more complex than simply having a laptop and a strong internet connection. The issue of cybersecurity in space is becoming increasingly concerning as the number of operational satellites continues to grow.

By the end of 2022, there were 6,718 operational satellites orbiting the Earth, representing a significant increase from the previous year. With 10,206 objects in space, predominantly satellites, the space environment is rapidly expanding.

Satellites play crucial roles in GPS navigation, military surveillance, and banking systems, making them attractive targets for potential hackers. But despite their vulnerability, instances of successful hacks on satellites are rare. So, how can a satellite be hacked, and what are the potential consequences?

How can a satellite be hacked?

While space may seem like a distant realm filled with satellites in remote galaxies, most satellites actually orbit in low earth orbit (LEO), between 99 and 1,243 miles above Earth. Physically accessing a satellite remains a challenge, but there are various methods hackers can employ to compromise satellites without venturing into space.

According to Anuradha Dhamal Dey, a SpaceX space ecosystem manager at Satellite Applications Catapult, potential satellite hacking methods include physical attacks, cyber attacks, and the use of kinetic anti-satellite (ASAT) technology. These methods have raised concerns about the security of space-based systems.

ASAT refers to any means of destroying a satellite, with kinetic ASAT involving physical strikes on satellites, such as through ballistic missiles or drones. While kinetic ASAT attacks are unprecedented outside of testing scenarios, non-kinetic attacks using malware or viruses pose a theoretical threat to satellite security.

Despite these risks, no actual satellite hacks have occurred yet. In 2023, the US Air Force organized Hack the Sat event to test satellite vulnerabilities, with three teams successfully breaching a satellite’s security.

What will happen?

While satellite hacking remains theoretical, the potential consequences of a successful attack are significant. Space plays a vital role in various industries, from national security and defense to everyday services like food delivery and entertainment.

Source: www.sciencefocus.com

‘Refining Bridge Editing: A Potential Improvement Over CRISPR for DNA Modification’

Bridge editing physically links two DNA strands

Visual Science

A powerful DNA-editing mechanism discovered in bacteria has the potential to enable much larger genome modifications than are currently possible with CRISPR-based techniques, but it is not yet clear whether it would work in human cells.

Patrick Shue Researchers at the Ark Institute in California call their new genome editing system the “bridge editing” system because it physically links, or bridges, two strands of DNA. “Using this system, we can modify large parts of the genome,” says Su. Su's team has figured out how bacterial “parasitic” DNA sequences naturally replicate using this system and how it can be applied to genome editing.

“We're excited about the possibility of making much broader genome modifications that go far beyond what we can do today with CRISPR,” he says, “and we see this as an important step toward a broader vision for genome design.”

CRISPR gene editing has revolutionized biology since it was introduced in 2012. It is used for a variety of purposes, and the first CRISPR-based therapeutic was approved last year. However, the basic form of CRISPR, which uses the Cas9 protein, is gene disruption rather than gene editing.

A standard CRISPR Cas9 protein has two parts: one part binds to a guide RNA molecule and looks for DNA that matches a specific section of the guide RNA. Custom guide RNAs are easy to create, so CRISPR Cas9 can be “programmed” to look for any part of the genome.

The second part of CRISPR Cas9 is a cutter that cuts the DNA when Cas9 binds to the target site. Once the cell has repaired the damage, Cas9 cuts it again. This action continues until an error is made during repair, resulting in the intended mutation of the target site.

While being able to mutate specific sites is useful, biologists want to make more precise changes, so they are modifying CRISPR proteins to edit DNA directly rather than relying on cellular repair mechanisms. For example, base editors can change one DNA letter to another without cutting the DNA, while prime editors can convert an extra section of guide RNA into DNA and add it to the target site.

These improved versions of CRISPR have the potential to treat a wide range of diseases, with several clinical trials already underway, but to address some diseases, more sophisticated genome modifications are needed. Many teams around the world are working on ways to achieve this. Some have realized that the mechanism by which genetic parasites cut and paste from one part of the genome to another, called IS110 elements, has potential because, like CRISPR, it is RNA-guided, but Hsu's team is the first to fully understand how it works.

The bridge-editing system consists of a so-called recombinase protein that binds to a guide RNA, such as the CRISPR Cas9 protein. What's unique about this system is that the guide RNA specifies two DNA sequences to seek out, not just one, Hsu's team found.

One sequence specifies the target site in the genome to modify, similar to CRISPR, and the other specifies the DNA to change. Using this system, DNA sequences of virtually any length can be added, deleted, or inverted.

There are already ways to do this, but they typically require multiple steps and leave behind a piece of extra DNA called a scar. “Bridge editing leaves virtually no scar,” Hsu says. “It offers an unprecedented level of control in engineering the genome.”

This means that it could be used for more than just replacing faulty genes, he says: It could also be useful for completely remaking the genomes of plants and animals. “What we want to do is go from inserting individual genes to doing chromosome-scale genome engineering,” Su says.

“The findings reported are certainly exciting and the underlying biology is truly surprising.” Steven Tang Bridge editing is being done at Columbia University in New York, but so far it has only been demonstrated to work in bacterial cells or in test tubes. Tang says it remains to be seen whether and to what extent bridge editing will work in complex cells like humans. But even if bridge editing doesn't work in initial tests in human cells, it may be possible to modify the system to work over time.

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Source: www.newscientist.com

Research shows active hydrothermal systems on small ocean planets have the potential to sustain life

Ocean worlds are planetary bodies with liquid oceans, often beneath an icy shell or within rocky interiors. In our solar system, several moons of Jupiter and Saturn are ocean worlds. Some ocean worlds are thought to have hydrothermal circulation, where water, rocks, and heat combine to pump and expel fluids to the ocean floor. Hydrothermal circulation influences the chemical composition of the water and rocks of ocean worlds and may help life develop deep beneath the icy surface. In a new study, planetary researchers used computer simulations of hydrothermal circulation based on well-understood systems on Earth to measure the effects of low gravity at values appropriate for ocean worlds smaller than our home planet. Simulations of ocean worlds with (lower) gravity result in fluid circulation that is roughly similar to that which occurs above and below the ocean floor on Earth, but with some key differences. Low gravity reduces buoyancy, so fluids do not become lighter as they heat up, which reduces their flow rate. This increases the temperature of the circulating fluids, which could lead to more extensive chemical reactions, possibly including those necessary to support life.

This diagram shows how Cassini scientists think rocks and water at the bottom of Enceladus’ ocean interact to produce hydrogen gas. Image courtesy of NASA/JPL-Caltech/Southwest Research Institute.

Rock-heat-fluid systems were discovered on the Earth’s ocean floor in the 1970s, where scientists observed releases of fluids carrying heat, particles, and chemicals.

Many of the vents were surrounded by a novel ecosystem, including specialized bacterial mats, red and white tube worms and heat-sensing shrimp.

For the new study, Professor Andrew Fisher from the University of California, Santa Cruz, and his colleagues used a complex computer model based on the hydrothermal cycle that occurs on Earth.

After varying variables such as gravity, heat, rock properties and depth of fluid circulation, the researchers found that hydrothermal vents could persist under a wide range of conditions.

If these flows occurred on an ocean world like Jupiter’s moon Europa, they could increase the chances of life surviving there as well.

“This study suggests that extraterrestrial ocean worlds may have supported low-temperature (but not hot enough for life) hydrothermal systems on timescales similar to those it took for life to become established on Earth,” Prof Fischer said.

The ocean circulation system on which the researchers based their computer model was discovered on the 3.5-million-year-old seafloor of the northwest Pacific Ocean, east of the Juan de Fuca Ridge.

There, cold undersea water flows through an extinct volcano (seamount), travels about 30 miles (48.3 km) underground, and then flows out into the ocean through another seamount.

“As water flows, it picks up heat, it’s warmer than when it entered, and its chemistry changes dramatically,” says Kristin Dickerson, a doctoral student at the University of California, Santa Cruz.

“The flow from seamount to seamount is driven by buoyancy – as water warms it becomes less dense and as it cools it becomes more dense,” Prof Fischer added.

“The difference in density creates a difference in fluid pressure within the rock, and the system is sustained by the flow itself. So as long as there is enough heat supplied and the rock properties allow for sufficient fluid circulation, the system will keep running. We call this a hydrothermal siphon.”

“Hot vent systems are primarily driven by sub-sea volcanism, while the Earth’s ocean floor experiences large amounts of fluid flowing in and out at much cooler conditions, driven primarily by Earth’s background cooling.”

“The flow of water through low-temperature vents is equivalent to all the rivers and streams on Earth in terms of the volume of water released, and accounts for about a quarter of the Earth’s heat loss.”

“About every 500,000 years, the entire volume of ocean water is pumped up and out of the ocean floor.”

Many previous studies of the hydrothermal circulation on Europa and Enceladus have considered hotter fluids.

“Cartoons and other illustrations often depict undersea systems that are similar to Earth’s black smokers, where cooler currents could occur just as much or even more than they do on Earth,” said Dr Donna Blackman from the University of California, Santa Cruz.

The results show that in very low gravity, such as on the ocean floor of Enceladus, the circulation can continue at low to moderate temperatures for millions or billions of years.

This could help explain why small ocean planets can have long-lived fluid circulation systems beneath their seafloors despite limited heating: the inefficiency of heat extraction could extend their lifetimes considerably, potentially for the entire lifetime of the solar system.

Scientists acknowledge that it is uncertain when active hydrothermal systems will be directly observed on the ocean planet’s seafloor.

The distance from Earth and physical characteristics pose significant technical challenges for spacecraft missions.

“It is therefore essential to make the most of the available data, much of which is remotely collected, and to leverage the understanding gained from decades of detailed study of the analog Earth system,” the authors concluded.

their paper Published in Journal of Geophysical Research: Planets.

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A.T. Fisher others2024. Gravitational maintenance of hydrothermal circulation in relation to the ocean world. Journal of Geophysical Research: Planets 129(6):e2023JE008202; doi:10.1029/2023JE008202

Source: www.sci.news

Potential Lunar Conflict: The Moon World War looms on the horizon

The Moon, Earth’s steadfast companion that remains in orbit, has been a popular subject of discussion since the early days of space exploration. Missions have been planned, rovers have explored its surface, and even a flag has been planted there.

But why all the interest? The Moon is over 400,000 km away from Earth, a considerable distance to travel, and it poses many challenges as a potential habitat for humans, such as exposure to solar radiation.

However, the Moon offers other advantages. Being largely untouched, it presents opportunities for planetary research, scientific experiments, and notably, mining for valuable resources.

There is a growing interest in lunar exploration, raising the important question of lunar ownership. Philosopher and author AC Grayling addresses this topic in his new book, “Who owns the moon?”

SF: Why are we interested in going to the moon, and will it ever happen?

ACG: The Moon holds vast resources, making it a lucrative target for mining operations. Coupled with the rapid pace of technological advancements, the obstacles to lunar exploration are likely to be overcome. Significant investments are being made in this endeavor, indicating the potential benefits that could be derived.


While some argue that lunar exploration is not feasible, the lure of valuable resources like Helium-3 for clean nuclear fusion makes the Moon an attractive destination for mining activities.

SF: So who actually owns the moon?

The 1967 Outer Space Treaty, agreed upon by the United Nations, asserts that the Moon cannot be militarized or claimed for sovereignty or ownership. It is considered a shared resource belonging to all of humanity.

With various nations eyeing lunar exploration and exploitation, concerns about potential conflicts arise, highlighting the need for clearer regulations and agreements.

What are the next steps? Will the law be strengthened?

Efforts are being made to establish binding regulations, but the presence of multiple space agencies and rivalries between nations complicate the process. Initiatives like the Artemis Accords aim to set guidelines for responsible behavior in space.

However, the prospect of a new space race between major powers like the US, China, and Russia raises concerns about the potential for conflict and competition in space.

Can history give us any indication of what might happen?

The Antarctic Treaty serves as a model for international cooperation in preserving shared resources. However, challenges to extend the treaty’s scope and conflicting claims in Antarctica hint at the complexities of managing common territories.

Similar issues could arise in lunar exploration, especially with the potential for valuable mineral resources like Helium-3. The absence of clear regulations and the lack of a universal agreement on space governance present significant hurdles.

Is there an argument to leave the moon alone?

Given the Moon’s vast and barren nature, concerns about environmental impacts are minimal compared to Earth. Utilizing lunar resources for space exploration and sustainable practices could be more beneficial in the long run.

What’s the next step after the moon?

The Moon’s potential as a refueling station for Mars missions opens up new possibilities for further space exploration. As colonies on celestial bodies evolve, questions of independence and governance will arise, shaping the future of human presence in space.

In conclusion, the direction of space activities will determine whether they align with values upheld on Earth or devolve into profit-driven ventures. Clear regulations and international cooperation are essential to ensure a sustainable and equitable future in space.


About our expert, A.C. Grayling

AC Grayling is a philosopher and author of the book “Whose Moon is It?” He is also the founder of the New College of the Humanities and a respected figure in literary criticism and intellectual discourse.

Source: www.sciencefocus.com

Chatbots in China under scrutiny for potential censorship and bias, say geologists

There is concern among geologists regarding the development of the GeoGPT chatbot, supported by the International Union of Geological Sciences (IUGS). They worry about potential Chinese censorship or bias in the chatbot.

Targeting geoscientists and researchers, especially in the Southern Hemisphere, GeoGPT aims to enhance the understanding of geosciences by utilizing extensive data and research on the Earth’s history spanning billions of years.

This initiative is part of the Deeptime Digital Earth (DDE) program, established in 2019 and primarily funded by China to promote international scientific cooperation and help countries achieve the UN’s Sustainable Development Goals.

One component of GeoGPT’s AI technology is Qwen, a large-scale language model created by Chinese tech company Alibaba. Geologist and computer scientist Professor Paul Cleverley, who tested a pre-release version of the chatbot, highlighted concerns raised in an article in Geoscientist journal.

In response, DDE principals stated that GeoGPT also incorporates another language model, Meta’s Llama, and disputed claims of state censorship, emphasizing the chatbot’s focus on geoscientific information.

Although issues with GeoGPT have been mostly resolved, further enhancements are underway as the system is not yet released to the public. Notably, geoscience data can include commercially valuable information crucial for the green transition.

The potential influence of Chinese narratives on geoscience-related questions raised concerns during testing of Qwen, a component of GeoGPT’s AI, prompting discussions on data transparency and biases.

Future responses of GeoGPT to sensitive queries, especially those with geopolitical implications, remain uncertain pending further development and scrutiny of the chatbot.

Assurances from DDE indicate that GeoGPT will not be subject to censorship from any nation state and users will have the option to select between Qwen and Llama models.

While the development of GeoGPT under international research collaboration adds layers of transparency, concerns persist about the potential filtering of information and strategic implications related to mineral exploration.

As GeoGPT’s database remains under review for governance standards, access to the training data upon public release will be open for scrutiny to ensure accountability and transparency.

Despite the significant funding and logistical support from China, the collaborative nature of the DDE aims to foster scientific discoveries and knowledge sharing for the benefit of global scientific communities.

Source: www.theguardian.com

New GLP-1 medications offer potential for weight loss and improved health

Exciting developments are on the horizon in the world of obesity medications.

Pharmaceutical companies are racing to create new drugs, building on the success of existing medications like Novo Nordisk’s Ozempic and Wegovi, as well as Eli Lilly’s Maunjaro and Zepbound.

In addition to targeting diabetes and weight loss, some experimental drugs show promise in improving liver and heart function while reducing common side effects such as muscle loss seen with current treatments. Data on 27 GLP-1 drugs in development will be presented at the 2024 American Diabetes Association meeting in Orlando, Florida.

According to Marlon Pragnell, PhD, the ADA’s vice president of research and science, the pipeline now includes a variety of drug candidates in different stages of development, creating an exciting landscape of innovation.

While most of the data currently available comes from animal studies or early human trials, some drugs may be available in the United States over the counter within a few years, with FDA approval likely further down the line.

As the field of GLP-1 drugs continues to expand, there is hope for more affordable medications with fewer side effects to become available, offering new possibilities for patients.

Exploring Different Hormones for Weight Loss

GLP-1 drugs function by slowing down the digestive process and promoting a sense of fullness. In addition to GLP-1, emerging weight-loss drugs are examining the impact of another hormone called glucagon, which can mimic the effects of exercise.

One such drug, Pemvidutide from Maryland-based Altimmune, combines glucagon with GLP-1 to potentially enhance weight loss effects.

Results from a Phase 2 trial involving obese or overweight adults showed promising weight loss outcomes, paving the way for further research into the drug’s potential benefits.

Altimmune’s Chief Medical Officer, Dr. Scott Harris, highlighted the drug’s ability not only to aid in weight loss but also to provide additional health benefits for liver and heart function while preserving lean body mass.

Altimmune plans to move forward with Phase 3 trials and aims to introduce the drug in the U.S. by 2028.

Competition and Cost Considerations

Having a variety of weight-loss drugs available can help address shortages and potentially drive down costs over time. The high prices of current medications like Wegobee and Zepbound in the U.S. can pose financial challenges for many patients.

Different patients may respond differently to various treatments, as highlighted by Dr. Fatima Cody Stanford of Harvard Medical School. Having a range of options is crucial to tailor treatments to individual needs.

Stay Informed with the Latest News on Weight Loss Drugs

New developments in the pharmaceutical world present opportunities for improved treatment outcomes and potentially life-changing solutions for patients struggling with obesity.

For individuals like Danielle Griffin, who have not seen the desired results from current medications, the prospect of innovative drugs offers hope and excitement for the future.

Advancements in Metabolic Health

Companies like Eli Lilly are exploring new combinations of hormones to enhance the efficacy of weight-loss drugs. Retatortide, a new injectable medication from Lilly, shows promising results in weight loss and blood sugar control.

Additional studies on drugs like Mazduchid highlight the potential for improved metabolic status and weight loss outcomes, paving the way for new treatment options in the near future.

These ongoing developments underscore the dynamic landscape of obesity treatment, offering hope for a new generation of medications that could revolutionize the field and improve outcomes for patients.

The Future of Obesity Treatment

As research and development in the field of obesity medications continue to advance, there is optimism for more effective, affordable, and patient-friendly treatments to become available in the coming years.

With the potential for improved metabolic health, weight loss outcomes, and reduced side effects, the next wave of obesity treatments holds great promise for individuals struggling with obesity-related health issues.

The ongoing innovation in this field signifies a new era of possibilities in obesity treatment, offering hope for a healthier future for many individuals.

Source: www.nbcnews.com

Madigen: Potential for Central Asia’s First UNESCO Geopark with these Incredible Rocks

The Madigen Formation is one of the richest Triassic fossil beds in the world, but few people have ever heard of it.

geo explorers club

About 235 million years ago, in what is now Central Asia, a small reptile fell into a freshwater lake and settled in the soft mud at the bottom.Creatures – named longiskamaIt means “long scales” after the strange feather-like protrusions on its back. It probably lived in the nearby forest, along with many other interesting animals, including a flying reptile known as a flying reptile. Chalovipteryx and Giga Titana giant praying mantis-like insect.

as longiskama's body slowly rotted, gradually turning to stone, continents drifted away, lakes dried up and reformed again and again, and the landscape above changed. Later, in the 1960s, Soviet paleontologist Alexander Sharov discovered reptile fossils. scientifically spotlighted In this little-known corner of the Soviet Union.

Today, the region is located in southern Kyrgyzstan and is a dusty landscape of colorful rock outcrops and dry riverbeds, surrounded by the snow-capped peaks of the Turkestan Mountains. These rocks are the remains of layers of mud and silt that were deposited on the lake bed. longiskama This formation is called the Madigen Formation after a nearby village.Paleontologists recognize it as One of the richest Triassic fossil beds in the world and Lagerstätte –’s site A beautifully preserved specimen – But few others have heard of Madygen.

That's about to change. If all plans go well, this year the region will become the world's first global geopark.

Source: www.newscientist.com

Lessons from Uninhabitable Venus: Exploring the Potential for Extraterrestrial Life

Given the diversity and complexity of endogenous and extrinsic processes that contribute to the maintenance of habitable conditions over geological and biological timescales, it is unclear how rocky planets become habitable and their status. Fully understanding how it is maintained is a fundamental challenge for planetary scientists and astrobiologists. In the face of this challenge, it is essential to exploit the full range of atmospheric evolution data for rocky planets within the solar system. Although Venus represents an apparent fringe member of planetary habitability, its contribution to understanding the prevalence of long-term temperate surface conditions in large rocky worlds remains poorly recognized. Upcoming missions to Venus, including NASA's VERITAS and DAVINCI, and ESA's EnVision mission, will begin to crystallize this understanding.

Kane and Byrne describe Venus as an anchor point where planetary scientists can better understand the conditions that prevent life on exoplanets. Image credit: Kane & Byrne, doi: 10.1038/s41550-024-02228-5.

“We often assume that Earth is a model of habitability, but when we consider this planet in isolation, we don’t know where the boundaries and limits are. Venus gives us that. '' said Dr. Stephen Cain, an astrophysicist at the University of California, Riverside.

“Although they also feature a pressure cooker-like atmosphere that could flatten humans in an instant, Earth and Venus share some similarities.”

“They have roughly the same mass and radius. Given their proximity to the planet, it’s natural to wonder why Earth looked so different.”

Many scientists believe that solar flux, the amount of energy Venus receives from the sun, caused a runaway greenhouse effect that doomed Earth.

“If Earth receives 100% of the solar energy, Venus collects 191%. Many people think that’s why Venus looks different,” Dr. Kane said.

“But wait a minute. Venus doesn’t have a moon, but that gives Earth something like ocean tides and affects the amount of water here.”

In addition to some of the known differences, more NASA missions to Venus will also clarify some of the unknowns.

Planetary scientists have no idea how big its core is, how it arrived at its current relatively slow rotational speed, how its magnetic field has changed over time, or the chemistry of its lower atmosphere. i don’t know.

“Venus has no detectable magnetic field. That may be related to the size of its core,” Dr. Kane said.

“The size of the core also gives us information about how the planet cools. Earth has a mantle, and heat circulates through its core. What’s going on inside Venus? I don’t know.”

“The interior of a rocky planet also influences its atmosphere. That is the case for Earth, and our atmosphere is primarily the result of volcanic gas emissions.”

Schematic cross-section of Earth and Venus. Major internal and atmospheric components are shown to scale. Image credit: Kane & Byrne, doi: 10.1038/s41550-024-02228-5.

NASA is planning two missions to Venus (DAVINCI and VERITAS) for the end of this decade, and Dr. Cain is supporting both.

The DAVINCI mission will explore the acid-filled atmosphere and measure noble gases and other chemical elements.

“DAVINCI measures the atmosphere from top to bottom. This is extremely useful for building new climate models and predicting this type of atmosphere elsewhere, including on Earth, as the amount of carbon dioxide continues to increase. ,” Dr. Kane said.

Although the Veritas mission will not land on the surface, it will allow scientists to reconstruct detailed 3D terrain, which could reveal whether the planet has active plate tectonics or volcanoes.

“Currently, our global map is very incomplete. Understanding how active a surface is and understanding how it has changed over time are very different. We need both types of information,” Dr. Kane said.

Ultimately, Dr. Kane and his co-author, Dr. Paul Byrne of Washington University in St. Louis, advocate such a mission to Venus for two main reasons.

One is that with better data, we can use Venus to confirm that our inferences about life on distant planets are correct.

“The somber thing about searching for life elsewhere in the universe is that we will never have in-situ data on exoplanets. We will never go there, land on them, or measure them directly. I don’t intend to,” Dr. Kane said.

“If we think there is life on the surface of another planet, we may never realize we are wrong and end up dreaming of a planet without life.” I guess.”

“We can only get it right by understanding the Earth-sized planets we can visit. Venus gives us that chance.”

Another reason to study Venus is that it can predict what Earth’s future will be.

“One of the main reasons we study Venus is because of our sacred duty as stewards of this planet to protect its future,” Dr. Kane said.

“My hope is that by studying how Venus came to be today, we can learn lessons from it, especially if it had a benign past that is now in ruins. The question is when and how.”

of review paper It was published in the magazine natural astronomy.

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Stephen R. Cain and Paul K. Byrne. 2024. Venus as an anchor point for planetary habitability. Nat Astron 8, 417-424; doi: 10.1038/s41550-024-02228-5

Source: www.sci.news

More Energy Recovery Potential in Wind Turbines Modeled After Condor Wings

The curved tip of a wind turbine blade, or winglet, based on the shape of a condor wing

Kashayar Ranamai Vahanbali

A design change inspired by the wings of the Andean condor could increase the energy produced by wind turbines.

Different types of birds have upturned tips at the ends of their wings, which help maximize lift. Similar features, known as winglets, are commonly used on aircraft wings, but have not been tested on the giant turbine blades used to generate electricity.

Kashayar Ranamai Vahanbali Researchers at the University of Alberta in Canada say collecting experimental data on wind turbines with winglets is extremely difficult due to their size.

His team designed a winglet based on the Andean condor, the heaviest flying bird in the world. The Andean condor can travel vast distances, despite weighing up to 15 kg.

Computer simulations of airflow through the turbine showed that these winglets reduced drag and increased efficiency by an average of 10%.

“Another perspective is that the winglets allow the turbine to capture more wind energy with minimal losses. [resistance]” says Ranamayvahanbury.

Winglets can be retrofitted after a turbine is manufactured, he said, by slipping “sock-like” pieces onto the ends of the blades. Researchers are developing an experimental setup to test models of wind turbine winglets.

Peter Majewski, who recently retired from the University of South Australia, said the research results made sense from an engineering and aerodynamics perspective, but retrofitting existing wind turbines would be prohibitive in terms of downtime and cost. He said it might be realistic.

But for new turbine blades, adding winglets during the manufacturing process can lead to significant performance improvements, he says.

topic:

  • aerodynamics/
  • Renewable energy

Source: www.newscientist.com

A fresh perspective on tinnitus and hearing loss may offer potential for their reversal

Ten years ago, while working as a DJ in Liverpool, England, James Rand would often leave work hearing strange sounds he knew weren't real: high-pitched growls or low-pitched rumblings. . These tinnitus symptoms always went away by the time he woke up… and one day in 2017, they didn't go away.

Doctors confirmed that the sounds were probably caused by Rand's exposure to loud music for hours at a time. There was no cure, no way to get him used to it. “I thought I would never hear silence again,” he says. “He was incredibly depressed.”

But today, the outlook for tinnitus treatment is not so bleak. New research has developed a neurostimulator that reduces the volume of sounds. Additionally, there are several treatments in development that can even stop tinnitus completely. “For the first time, we are discussing potential treatments,” he says. Stéphane Maison at Harvard Medical School.

These insights also shed light on common causes of hearing loss. In fact, they suggest that the same treatments for tinnitus may also restore hearing in people who have become partially deaf due to aging. “The way we think about hearing loss has completely changed,” Maison says.

What is tinnitus?

Tinnitus is one of the most common long-term medical conditions. Affects up to a quarter of older adults. While the crying and rumbling sounds that Rand experiences are common, others may hear whistling, humming, clicking sounds, and even musical hallucinations. Sound can be annoying and distracting, and in some cases can cause depression and anxiety…

Source: www.newscientist.com

Cloud Seeding: An Explanation and its Potential Role in the Dubai Floods

Driver abandons car after rainstorm in Dubai, United Arab Emirates, April 17

Christopher Pike/Bloomberg/Getty

Record rainfall has hit the Arabian Peninsula this week, causing flooding in Dubai, Abu Dhabi and other coastal cities in the United Arab Emirates. The extreme weather sparked speculation on social media that the UAE’s long-standing cloud seeding program may have played a role. However, cloud seeding almost certainly does not have a significant impact on flooding.

How unusual was the recent rain in the Arabian Peninsula?

It was the most extreme event in the UAE since record-keeping began in 1949. according to to the state-run Emirates News Agency. From April 15th to 16th, some parts of the country received more than their normal annual rainfall in a 24-hour period. Heavy rains in desert regions are not uncommon, but they are not unheard of – as the UAE sees it. heavy rain and flooding For example, 2016.

A drainage system in a coastal city in the United Arab Emirates (UAE) has been overwhelmed by spills, causing flooding. Dramatic images of a plane driving through stagnant water at Dubai International Airport have been widely shared online.

In neighboring Oman, died in flash flood At least 18 people. Parts of Bahrain, Qatar and Saudi Arabia also experienced unusual rainfall.

What is cloud seeding? Did it affect extreme rain?

Cloud seeding is a way to increase precipitation, From about the 1940s. This involves spraying powders such as silver iodide onto clouds from airplanes or rockets, or burning them from stations on the ground. Droplets of supercooled water form around these particles and fall to the ground as rain or snow.

Since 2002, the UAE has maintained one of the largest cloud seeding programs in the world. Planes regularly fly cloud-seeding missions in an effort to increase freshwater resources in arid regions.

Meteorologists at the UAE’s National Center of Meteorology (NCM) have further fueled speculation that cloud formations may be responsible for the recent rains. Said bloomberg news That in the days before the storm, planes had spread clouds over the country. However, NCM later stated: statement That no seed was sown during the storm.

“We take the safety of our employees, pilots and aircraft very seriously,” the company said. “NCM does not conduct cloud seeding operations during extreme weather conditions.”

Even if cloud formation had occurred during the storm, it would have had at most a small effect on precipitation and would have been localized. The extent of rainfall across several countries and the generally limited influence of cloud species suggest that cloud occurrence almost certainly does not play a significant role. “There is no technology that can create or even significantly alter this type of rainfall event.” Maarten Ambaum at the University of Reading, UK statement.

He noted that cloud seeding would have little impact on clouds that were already predicted to bring rain to the region. And that assumes that cloud seeding is effective at all.

“Many claims of successful cloud seeding are false, scientifically flawed, or actually fraudulent,” he says. Andrew Dessler at Texas A&M University. “This makes most atmospheric scientists very skeptical about cloud formation.”

What weather factors were behind the rain?

The extreme precipitation was caused by large storms called mesoscale convective systems. Suzanne Gray Researchers at the University of Reading say this happens “when many individual thunderstorms coalesce to form a single large high-level cloud shield.”

Forecasters had predicted a high risk of flooding in the area for at least a week before the storm.Writing in progress XJeff Berardelli, a meteorologist at WFLA-TV in Florida, linked the storm to a blocking pattern created by a slow-moving jet stream.

Has climate change made rain worse?

Further analysis is needed to link this particular event to climate change, but climate change likely plays a role.

“These types of heavy rainfall events are likely to become more extreme with climate change, as a warming atmosphere retains more water vapor,” Ambaum said. Changes in temperature can also affect atmospheric circulation patterns in the form of changes in precipitation.

For example, recent study The same type of storm that caused this extreme rainfall has occurred in the region 95 times since 2000, with the most frequent occurrences on the Arabian Peninsula in March and April, researchers found. However, it has also been found that the duration of these storms has increased over the UAE since 2000, which may be linked to rising temperatures.

Alternative climate modeling study They predict that annual rainfall in the UAE will increase by 10 to 25 percent by mid-century, characterized by more intense precipitation events.

topic:

  • climate change/
  • Abnormal weather

Source: www.newscientist.com

Exploring the Potential of Graphene: A Revolutionary Material in Materials Science

Twenty years ago, scientists announced the creation of a new miracle substance that would revolutionize our lives. They named it graphene.

Graphene is made up of a single layer of carbon atoms arranged in a hexagonal pattern, making it one of the strongest materials ever produced. It is more resistant to electricity than copper and has excellent heat conductivity.

The potential applications of graphene seemed limitless, with predictions of ultra-fast processors, quicker battery charging, and stronger concrete. It was even proposed as a solution for potholes in roads.


Professor Andre Geim (left) and Professor Konstantin Novoselov from the University of Manchester discovered graphene. Photo: John Super/AP

The scientists behind the discovery, Andre Geim and Konstantin Novoselov, received the Nobel Prize in Physics in 2010 for their work. The National Graphene Institute was established at the University of Manchester.

Despite the initial hype, the graphene revolution has not materialized as expected. Challenges in scaling up production have hindered its widespread adoption.

Sir Colin Humphreys, a materials science professor at Queen Mary University of London, pointed out that the main issue lies in the difficulty of producing graphene on a large scale.

He explained that the original method of creating graphene was not conducive to mass production and that significant investments by companies like IBM, Samsung, and Intel have been made to develop scalable production methods.

Recent advancements in manufacturing techniques show promise for the resurgence of graphene technology. Companies like Paragraph are now producing graphene-based devices in large quantities.

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Graphene-based devices are being used for various applications, including sensors for detecting magnetic fields and differentiating between bacterial and viral infections.

Additionally, graphene devices are expected to be more energy-efficient than current technologies, offering a promising future for the material.

While the graphene revolution may have been delayed, it holds the potential to address pressing global challenges and significantly impact modern life.


Graphene “has the potential to make a real difference to modern life,” says Sir Colin Humphreys, professor of materials science.
Photo: AddMeshCube/Alamy

The hyped science failed to make the grade.

  • nuclear power “Our children will have immeasurably cheap electrical energy in their homes.” – Louis Strauss, then chairman of the U.S. Atomic Energy Commission, in 1954.

  • Sinclair C5 “This is the future of transportation” – promotional materials for the 1985 Sinclair C5 electric scooter/car. Sales in the first year were predicted to be 100,000 units, but only 5,000 units were sold. Project has been abandoned.

  • medical advances “The time has come to close the book on infectious diseases and declare that the war on epidemics has been won” – in the words of Dr. William H. Stewart, Surgeon General of the United States from 1965 to 1969.

Source: www.theguardian.com

The Future of Smart Textiles: Harnessing the Potential of Wearable Technology from the Human Body

From T-shirts with changing messages to carpets that can detect your position, the future of smart textiles seems to come straight out of a sci-fi novel.

Researchers now claim they have created a smart fiber that can achieve just that, without the need for a battery pack.

A team of Chinese researchers have developed textile-based electronics that utilize the human body as part of a circuit to harness electromagnetic energy from the environment.

This innovation could pave the way for a “body-bound” fiber electronics technology that functions without electronic chips or batteries and could be applied in various scenarios.

Co-author Chengyi Hou from Donghua University in Shanghai explained, “When electromagnetic energy passes through a fiber, it is converted into different forms of energy, including visible light or radio waves. Therefore, the fiber not only emits light but also produces an electrical signal when in contact with the human body.”

Hou highlighted that these radio signals are programmable by manipulating different aspects of the system, such as the fiber’s contact area with the body and its diameter.

The team stated that this method resolves a major challenge in integrating electronic systems into textiles, which is the necessity of rigid components.

Hou mentioned, “We have successfully achieved mass production of this new type of fiber electronics, which is as thin and soft as traditional fibers. The next step is to implement it.”

The team has created prototypes like a wearable cloth display with a cloth keyboard, intended for individuals with hearing impairments to aid in communication, as well as textile controllers for gaming.

Additionally, they developed a wireless tactile carpet that illuminates underfoot, providing emergency lighting at night and wirelessly transmitting signals to control household devices like lights.

Researchers have created a carpet that can glow underfoot and transmit signals that can be used to control switches in appliances such as lights. Photo: Yang Weifeng

Read more about the study here. The team assures that the fiber is constructed from three layers of inexpensive materials, making it durable, washable, and sweat-resistant.

An accompanying article suggests that this technology can also be utilized in robots, robotic prosthetics, and capturing haptic information to enhance human interactions and object recognition.

Dr. Luigi Occhipinti, a research director at the University of Cambridge specializing in smart electronics, biosystems, and AI, acknowledged the potential of this approach.

He stated, “By being constantly surrounded by various electromagnetic fields, we are developing innovative electronic textiles with skin sensors and unconventional electronics, powered uniquely through energy harvesting. This has the potential to unlock a new realm of self-powered wearable electronics for continuous health monitoring.”

Source: www.theguardian.com

Microsoft raises concerns about China’s potential disruption of US, South Korea, and India elections using AI technology

Following a dry run of Taiwan’s presidential election this year, China is anticipated to disrupt elections in the United States, South Korea, and India with artificial intelligence-generated content, as warned by Microsoft.

The tech giant predicts that Chinese state-backed cyber groups will target high-profile elections in 2024, with North Korea also getting involved, according to a report released by the company’s threat intelligence team.

“As voters in India, South Korea, and the United States participate in elections, Chinese cyber and influence actors, along with North Korean cyber attack groups, are expected to influence these elections,” Microsoft mentioned.



Microsoft stated that China will create and distribute AI-generated content through social media to benefit positions in high-profile elections.

Although the immediate impact of AI-generated content seems low in swaying audiences, China is increasingly experimenting with enhancing memes, videos, and audio, potentially being effective in the future.

During Taiwan’s presidential election in January, China attempted an AI-powered disinformation campaign for the first time to influence a foreign election, Microsoft reported.

The Beijing-backed group Storm 1376, also known as Spamoflage or Dragonbridge, heavily influenced Taiwan’s elections with AI-generated content spreading false information about candidates.

Chinese groups are also engaged in influencing operations in the United States, with Chinese government-backed actors using social media to probe divisive issues among American voters.

In a blog post, Microsoft stated, “This may be to collect intelligence and obtain accurate information on key voting demographics ahead of the US presidential election.”

The report coincides with a White House board’s announcement of a Chinese cyber operator infiltrating US officials’ email accounts due to errors made by Microsoft, as well as accusations of Chinese-backed hackers conducting cyberattacks targeting various entities in the US and UK.

Source: www.theguardian.com

Is the potential for more powerful electric bikes cause for concern over increased fire risk?

The UK Government has initiated a consultation to gather public and industry input on increasing the legal power of electric bike models from 250W to 500W in the UK. This move has sparked concerns in the fire protection community.

Electric bicycles utilize various types of batteries, with lithium-ion technology being the common choice. These batteries come in different shapes and sizes, such as cylindrical or box-shaped configurations.

Battery packs in electric bikes are composed of multiple cells connected in series and parallel to provide the necessary voltage and capacity. Incidents of fires linked to lithium-ion batteries are on the rise, posing risks to users of electric bikes and e-scooters.

Recent data disclosed in May 2023 by the Guardian newspaper revealed that defective electric bikes and e-scooters have caused injuries to 190 individuals and claimed eight lives in the UK. The London Fire Brigade noted a substantial increase in battery-related fires in 2023, with a rise of 78% compared to the previous year.

Potential causes of fires in lithium-ion batteries include mechanical or thermal shock, overcharging, and reactive materials interacting with each other, leading to heat generation and abnormal electrical behavior. Despite the benefits of higher wattage batteries in electric bikes, there are concerns about the increased risk of fires and other safety issues.

To mitigate the risk of battery fires, users are advised to avoid tampering with batteries, charge them within the recommended parameters, and store them in a safe environment away from flammable materials. Adherence to manufacturer guidelines and proper disposal of damaged batteries are crucial in preventing incidents of fires.

Source: www.sciencefocus.com

The Importance of Updating Outdated Software for U.S. Small Businesses: Avoiding Potential Losses

C
Poor and outdated technology is costing the United States enormous amounts of money.according to
recent columns The Wall Street Journal said it would cost more than $1.5 trillion to fix, with “cybersecurity and operational failures, failed development projects, and maintenance of outdated systems costing $2.41 trillion annually.” There is.


According to the magazine, this “technical debt” lurks beneath the shiny newness of “an accumulation of band-aids and outdated systems not intended for today's use,” all of which need updating. It is said to be extremely sensitive.

And I don't know that.

I've been dealing with this problem every day for the past 20 years. My life revolves around outdated systems, outdated software, and patched databases. My company sells customer relationship management (CRM) software primarily to small and medium-sized businesses. And look at the old technology they still have.

It's not uncommon to come across older versions of Microsoft Office. One of his companies I know is still running Office 97. I see companies using QuickBooks on desktop computers. Remember ACT and GoldMine for contact managers? Yes, they're still there. Great Plains? MAS90? Yes, there are still remnants of these ancient accounting systems in today's products manufactured by Microsoft and Sage.

It's not uncommon to encounter companies with internal networks running legacy client/server applications on Windows machines.Approximately 81% of companies
still writing paper checks to suppliers. My company's biggest competitor is not any other CRM software. Someone is walking away from a prehistoric, proprietary system built on top of his FileMaker Pro, which hasn't been updated since the system's creator passed away ten years ago.

Over the years, I have never faulted small business owners for not upgrading.

These people spent a lot of money implementing software systems back in the day. They'd have to come up with a pretty good reason to scrap it all and start fresh. Cloud? Better security? More integration? Maybe. But then again, wouldn't that money be better spent buying new equipment, repairing the warehouse roof, or medical care? And don't we hear about the mistakes made by ~? ?
microsoft and
Google And A.I.
“hallucination” And that
data breach Are the world's smartest people at the biggest technology companies that are supposed to work for them? Can we trust these companies and their shiny new applications? Why invite trouble?

Replacing or upgrading technology is one of the many decisions businesspeople have to make every year. They know the chaos it causes. And many of my clients shrug their shoulders and say it's not broken so why fix it?

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Understood. But now my feelings are starting to change. No, I'm not siding with big tech companies. It's about inheritance.

More than half of small business owners in this country are over 50 years old, and the baby boomers currently running companies will likely aim to take the next step in the not-too-distant future. They expect to make the most money from the business they have built over the past few decades. But the same people who saved money on technology upgrades to invest elsewhere will be shocked. why?

Because this is a world of big data and unless the technology is up to date, the price of your business will be greatly affected. This is not a technical issue. It's a matter of evaluation. Buyers will quickly discount the purchase price to cover the cost of having to upgrade or replace these older systems.

My advice to business owners looking to leave their companies within the next 10 years is that it's time to upgrade. Otherwise, “technical debt” will cost you dearly.

Source: www.theguardian.com

Unveiling the unexpected potential and serious risks of AI feigning empathy

It has been 100 days since the war in Gaza began, and it has become increasingly difficult to read the news. Her husband told me it might be time to talk to a therapist. Instead, on a cold winter morning, after fighting back tears as I read another tale of human tragedy, I turned to artificial intelligence.

“I’m pretty depressed about the state of the world,” I typed into ChatGPT. “It’s natural to feel overwhelmed,” the magazine responded, offering a list of practical advice, including limiting media exposure, focusing on the positive and practicing self-care.

I closed the chat. I was sure that I would benefit from doing all this, but at that moment I didn’t feel much better.

It may seem strange that an AI would even try to provide this kind of assistance. But millions of people have already turned to his ChatGPT, a professional therapy chatbot that provides convenient and inexpensive mental health support. Even doctors are said to be using AI to create more empathetic notes for patients.

Some experts say this is a boon. After all, AI may be able to express empathy more openly and tirelessly than humans, unhindered by shame or burnout. “We admire empathetic AI” by a group of psychological researchers I wrote recently.

But others are not so sure. Many people question the idea that AI can be empathetic and worry about the consequences if people seek emotional support from machines that can only pretend to care. Some even wonder if the rise of so-called empathic AI might change the way we think…

Source: www.newscientist.com

The potential damage to skin health from wearing makeup during exercise

Exercising while wearing foundation changes the properties of your skin.

One inch punch/Shutterstock

Wearing foundation while exercising can affect your skin health by changing the size of your pores and subsequently altering the release of sebum, which is responsible for keeping you healthy.

Lee Seok Ho The researchers at Texas A&M University in San Antonio recruited 43 college students, 20 men and 23 women. Participants first washed their faces with facial cleanser. The researchers then measured skin variables in different areas of the face, including pore size and sebum production.

A single layer of foundation was then applied to all participants’ faces, either on the forehead or cheeks, depending on the participant’s preference.

They then did a 20-minute moderate workout by running on a treadmill at 3 miles per hour (mph) for 5 minutes, 4 miles per hour for 10 minutes, and 5 miles per hour for 5 minutes.

After the training, the researchers repeated various skin measurements and found that areas with foundation had less sebum production than areas without makeup.

“This is a shining example of the negative effects of makeup during exercise,” the researchers wrote in their paper. “In this study, makeup use clogged pores and resulted in negative sebum scores.” The optimal amount of sebum is unknown, and too much can cause acne, while too little can cause skin irritation. To do.

Participants’ pore size also increased significantly in areas without foundation, but did not change significantly in areas with makeup. This suggests that this foundation may be inhibiting the natural enlargement of pores during exercise, preventing the release of sebum and sweat, which moisturize and cool the skin. The researchers did not assess whether these changes were related to skin problems.

Wearing foundation during exercise may not have a significant effect on most people who train for relatively short periods of time, but “we don’t know the effect on endurance-type athletes,” Lee said. say. The research team now wants to investigate the effects during longer exercise routines.

Shari Lipner Researchers at Weill Cornell Medicine in New York say the study’s split-face design is a good approach, but complicates comparisons because our skin characteristics vary across different parts of the face. Additionally, she says, the skin around the nose, mouth and eyes has a different thickness compared to the skin on the forehead and cheeks, so ideally these areas should have been studied as well.

topic:

Source: www.newscientist.com

The Sun-Fueled Black Hole: Potential to Shine as the Brightest Object in the Universe

CAPE CANAVERAL, Fla. — Researchers have identified a quasar with a black hole at its center that may be the most luminous object in the universe. This quasar is growing at an incredible rate, capable of consuming an amount equivalent to the sun in a single day.

The record-breaking quasar shines 500 trillion times brighter than the sun. Scientists reported in the journal Nature Astronomy that the black hole fueling this quasar is more than 17 billion times more massive than the sun.

Despite appearing as mere dots in images, scientists believe quasars to be formidable entities.

The disk of luminous gas and other material orbiting a quasar’s black hole is akin to a cosmic hurricane.

“This quasar is the most violent place in the universe as we know it,” said lead author Christian Wolff of the Australian National University.

The object, known as J0529-4351, was initially discovered by the European Southern Observatory in 1980 and misclassified as a star. It was not confirmed to be a quasar until last year, after telescope observations in Australia and the Atacama Desert in Chile.

“What’s interesting about this quasar is that it’s hiding in plain sight and was previously misclassified as a star,” said Priyamvada Natarajan of Yale University.

Further analysis revealed that the quasar consumes the equivalent of 370 suns a year, or one sun a day, and the black hole at its center has a mass between 17 billion and 19 billion times that of the sun. More observations are needed to understand its growth rate.

Quasars are located 12 billion light years away and have existed since the beginning of the universe. One light year is 5.8 trillion miles.

Source: www.nbcnews.com

Five asteroids narrowly miss Earth today, including one with the potential to cause widespread destruction

Today, not one, but five asteroids are hurtling past Earth, all at their closest approach.

The largest one was discovered just a few weeks ago. Potentially Dangerous 2024 BR4. Measuring between 140 and 300 meters in length, it is a sizable chunk of space rock. At its highest estimate, it would be about the size of an oil tanker, six Olympic-sized swimming pools, or as tall as New York City's Chrysler Building.

And just like the box of chocolates you might stuff your cheeks with, we have a few more surprises in store for you on the day. Dr. Darren Baskillan astronomer at the University of Sussex, said:

“On Wednesday, February 14, 2024, a total of five asteroids will pass Earth, all within 5 million kilometers.”

It may seem like a long way, but from an astronomical perspective, it's just a stone's throw away.

“The closest of these five is asteroid 2024 CU1, which is scheduled to pass about 52 percent further away than the Moon and is about 20 meters in diameter.”

In 2024, CU1 will be closest at 1:31 PM GMT (+/- 1 minute). However, it is only 20 meters in diameter, much smaller than the much talked about “city killer” called 2024 BR4.

How close will asteroid 2024 BR4 get?

Asteroid 2024 BR4, one of a group of asteroids that will fly past Earth today, will make its closest approach at a distance of 4.6 million km (2.86 million miles). In terms of AU, this is approximately 0.03 AU, well within the criteria for designation as a potentially hazardous object (see Meaning of a “Potentially Hazardous” Asteroid below).

(To convert kilometers per mile to AU, divide the distance in kilometers per mile by the distance in 1 AU of the same unit.)

Closest approach is expected to occur at 11:03 GMT today (±1 minute).

Will asteroid 2024 BR4 collide with Earth?

The Valentine's Day asteroid is hurtling through space at about 44,880 kilometers per hour (27,887 miles per hour), only slightly faster than the average speed recorded by Galileo during his six-year mission to Jupiter, but we… No need to worry. About influencing our heavenly oasis.

It passes us safely and poses no immediate threat to Earth.

“Asteroid 2024 BR4 will pass close to Earth 12 times further away than the Moon,” Baskill explains.

What do we know about Asteroid 2024 BR4?

Unfortunately, there are very few. In general, the larger the object, the brighter it is (the brighter the object, the lower the magnitude). NASA assigned asteroid 2024 BR4 a magnitude of 21.457.. It's not very bright.

However, we also need to know the object's albedo (surface reflectance), which is currently unknown. Current best estimates place the asteroid's size between 140 and 300 meters in diameter. But we know its trajectory with relative certainty. And today's visit will bring us the closest in 120 years to realizing BR4 in 2024.


Is Russia’s Space Weapon Nuclear and a Potential Threat?

Mysterious new weapon could threaten satellites in Earth orbit

Key Fame/Shutterstock

According to a series of reports, the US government has privately warned lawmakers and European allies that Russia is planning to launch a nuclear-capable space weapon.

The news comes after U.S. House Intelligence Committee Chairman Mike Turner announced: vague warning It cited a “grave national security threat” and asked US President Joe Biden to “declassify all information related to this threat” for more public discussion. Since then, news reports have revealed additional details about what Russia's mystery weapon is. Here's what we know so far:

Does this mean Russia aims to deploy nuclear missiles and bombs into space?

This point remains unclear.Report from ABC News and new york times The term “nuclear weapon” may mean a weapon capable of producing an explosion involving a fission or fusion reaction.If this is true, it would be a violation of the rules 1967 Outer Space TreatyIt prohibits signatories, including Russia and the United States, from placing nuclear weapons or other weapons of mass destruction in space.

Although a nuclear explosion in space would not directly harm people on Earth, it could destroy and disable multiple satellites.When the United States detonated a nuclear bomb in low Earth orbit during that period starfish prime In a 1962 experiment, the resulting radiation damaged or destroyed about a third of the satellites in low Earth orbit at the time.

However, there is another possibility that does not involve nuclear weapons.

What else does Russia have in its nuclear capabilities in space?

Russian space weapons may simply use nuclear power to power onboard systems. PBS News Hour U.S. officials said the Russian weapon was “probably nuclear-powered.”

Russia and the United States have used various forms of nuclear power in space for decades. One form includes nuclear fission reactors, such as those found in civilian nuclear power plants, which derive their power from an ongoing nuclear chain reaction.

The United States launched an experimental nuclear reactor into space in 1965, while Russia reportedly launched at least 34 nuclear reactors aboard satellites between 1967 and 1988. World Nuclear Association.

The United States, Russia, and other countries have also launched space missions using radioisotope systems. These use heat from the natural decay of radioactive materials as a power source, but they provide much less power than nuclear fission reactors.

What does this Russian space weapon actually do?

News reports agree that Russian weapons are designed to target satellites in space, rather than directly harming anyone or anything on the ground. However, if this weapon is able to knock satellites out of orbit, these objects could fall to the planet's surface and cause severe damage. If they blow away, the resulting cloud of space junk could threaten other satellites and even the International Space Station. This could even trigger a Kessler syndrome scenario, where a chain reaction of space debris gets out of control and makes it virtually impossible for satellites to survive in Earth orbit.

Various countries, including Russia, the United States, China, and India, have previously tested anti-satellite weapons (ASATs), which shoot missiles from Earth and shoot down objects in orbit. But countries have been much quieter about whether they have actually deployed ASAT weapons into space.

What does Russia say about the potential of this weapon?

A spokesperson for Russian President Vladimir Putin's government reportedly called the U.S. warning a “malicious hoax” aimed at pushing the U.S. Congress to pass legislation authorizing more military aid to Ukraine. Ta. Reuters. Since Russia launched a full-scale invasion of Ukraine in February 2022, the United States and Europe have supported Ukraine's military resistance against Russian forces.

Why does Russia need new anti-satellite weapons?

Satellites are important for both military and civilian applications that have a huge impact on modern life. They monitor the weather, power GPS systems, provide space-based surveillance, and enable communications. For example, SpaceX's Starlink satellite constellation has proven essential to the Ukrainian military in coordinating drone and artillery fire against Russian forces on the battlefield.

A U.S. official quoted by PBS NewsHour suggested that Russian space weapons have “electronic warfare capabilities to target U.S. satellites critical to U.S. military and civilian communications.”

According to some sources, Russia has spent years developing a space-based electronic warfare system that can jam communications signals to and from satellites. report This is by the Secure World Foundation, a space security organization based in Colorado.Victoria Samson at the Secure World Foundation Said Such a Russian space weapon could be powered by nuclear power.

So how dangerous is this new anti-satellite weapon?

The good news is that if this space weapon sabotages satellites rather than physically destroying them, it will not cause a catastrophic space debris scenario like Kessler syndrome. However, it can still be dangerous.

Space weapons that use electronic warfare to jam signals could effectively disable satellites. That could disrupt critical battlefield communications, render GPS guidance systems inoperable and obscure reconnaissance satellites, making it more difficult for the United States to coordinate military forces around the world.

topic:

Source: www.newscientist.com

Concerns Raised Over Potential Further Censorship of Pro-Palestinian Content in Meta’s Hate Speech Policy Review

The Guardian confirmed that Meta is considering expanding and “reconsidering” its hate speech policy regarding the term “Zionist.” On Friday, the company contacted and met with more than a dozen Arab, Islamic, and pro-Palestinian groups to discuss plans to review its policies to ensure that “Zionist” is not used as a substitute for Jewish or Israeli. An email seen by the Guardian revealed this information.

According to an email sent by Meta representatives to invited groups, the current policy allows the use of “Zionist” in political discussions as long as it does not refer to Jewish people in an inhumane or violent manner. The term will be removed if it is used explicitly on behalf of or on behalf of Israelis. The company is considering this review in response to recent posts reported by users and “stakeholders,” as reported by The Intercept.

Senator demands answers on reports of Meta censoring pro-Palestinian content

Another organization received an email from a Meta representative stating that the company’s current policy does not allow users to attack others based on protected characteristics and that a current understanding of language people use to refer to others is necessary. The email also mentioned that “Zionist” often refers to the ideology of an unprotected individual but can also refer to Jews and Israelis. The organizations participating in the discussions expressed concerns about the changes leading to further censorship of pro-Palestinian voices.

In addition, Meta gave examples of posts that would be removed, including a post calling Zionists rats. The company has been criticized for unfairly censoring Palestinian-related content, which raises concerns about the enforcement of these policies.

In response to a request for comment, Meta spokesperson Corey Chambliss shared a previous statement regarding the “increasing polarized public debate.” He added that Meta is considering whether and how it can expand its nuanced response to such language and will continue to consult with stakeholders to improve the policy. Policy discussions take place during high-stakes periods of conflict, and accurate information and its dissemination can have far-reaching effects.

More than 25,000 Palestinians have been killed since the attack on Gaza began in October 2023. Implementing a policy like this in the midst of a genocide is extremely problematic, and it may cause harm to the community, as stated by an official from the American Arab Anti-Discrimination Committee.

Source: www.theguardian.com

The Potential of Minecraft for Developing Adaptive AI

Minecraft is a game for humans, but it can also be useful for AI

Mine Craft

Mine Craft Not only is it the best-selling video game of all time, it could be the key to creating adaptive artificial intelligence models that can handle a variety of tasks just like humans.

stephen james and colleagues at the University of the Witwatersrand in South Africa developed a benchmark test in which. Mine Craft Measure the general intelligence of your AI model. MinePlanner evaluates AI's ability to ignore unimportant details when solving complex problems in multiple steps.

According to James, much AI training is “cheating” by giving the model all the data it needs to learn how to do a job, and nothing irrelevant. While this is a useful approach if you're writing software to perform a specific task, such as predicting the weather or folding proteins, it's not useful if you're trying to create artificial general intelligence (AGI).

James says that future AI models will need to tackle wicked problems, and he hopes MinePlanner will guide that research. The AI ​​working to solve in-game problems recognizes scenery, extraneous objects, and other details that are not necessarily needed to solve the problem and should be ignored. You need to investigate your surroundings and decide for yourself what is necessary and what is not.

MinePlanner consists of 15 construction problems, each with easy, medium, and hard settings, for a total of 45 tasks. The AI ​​may need to perform intermediate steps to complete each task. For example, building a series of stairs to place blocks at a certain height. This requires AI to narrow down the problem and plan ahead to achieve the goal.

Experiments with state-of-the-art planning AI models ENHSP and Fast Downward, open-source programs designed to process sequential operations in pursuit of an overall goal, show that both models successfully complete difficult problems. I couldn't do it. Fast Downward was only able to complete one medium problem and five easy problems, while ENHSP completed all but one easy problem and all but two medium problems. By completing all of the above tasks, they achieved slightly better results.

“You can't step in and tell a human designer exactly what to care about and what not to care about for every task that an AI needs to solve,” James said. say. “That's the problem we're trying to address.”

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Source: www.newscientist.com

The Potential Harmful Effects of Spiral Scratches on Contact Lenses

Contact lenses with a spiral design

Laurent Galinier

Lenses featuring a trippy spiral design could be an alternative to traditional multifocal lenses. It seems to produce clearer images than standard multifocal lenses, even in dimly lit areas.

The lens was created by the inventor Laurent Galinier.when bertrand simon He met Galinier through a scientific collaboration at the Institute of Optics Graduate School in France, and he immediately wanted to test lenses in the lab.

They are round lenses like traditional contact lenses, but the surface is carefully turned into a spiral using a lathe. This spiral shape changes the path that light rays take through the lens. That is, the lens does not have a single focal point, but several focal points, some closer to the lens and some farther from it.

It's unclear exactly how the spiral shape does this, but Simon said it appears to twist the light rays and create vortexes of light (like small tornadoes of light) that somehow influence each other. ing.

In the lab, Simon and his colleagues analyzed laser light passed through a spiral lens and simulated the process on a computer. In direct comparison with traditional multifocal lenses, the spiral lenses provided more clarity and detail when more light passed through them, and performed better in dim light conditions.

Therefore, spiral lenses may be suitable under various lighting conditions. For example, it could be useful for people who use multifocal lenses while driving at night, Simon said. He tried the spiral contact lenses himself and said that while the hard material was uncomfortable in contact with his eyes, it saved him the hassle of removing his glasses to look at his cell phone. With the spiral lens, I could see the screen clearly.

james wolfthorn According to researchers at Aston University in the UK, many people experience problems focusing on nearby objects, even if their distance vision is corrected. Innovations like spiral lenses are promising, but only clinical trials can prove how much of a difference new technology will actually make for people, he says.

Simon says it's possible to create a more compact camera by replacing part of the lens with a spiral lens version, but the team will first investigate the science behind spiral light. We would like to do further testing.

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Source: www.newscientist.com

The Formation and Potential Destruction of the Himalayas by Earth’s Tectonic Plates

Deep underground in the heart of Asia, two giant plates are colliding with each other. Violent, slow-motion collisions between the geological plates are continuously shaping the towering Himalayas. However, newly discovered research suggests that this ongoing tectonic collision is also dividing Tibet in half.

A group of Chinese and American scientists conducted a study of underground seismic waves from earthquakes in and around Tibet and analyzed the geochemical composition of gases in surface hot springs. They found evidence that the Indian plate may be behaving unexpectedly as it collides with the Eurasian plate.

This research, which has not yet undergone peer review, was presented at the American Geophysical Union’s annual meeting in December. The scientists theorize that as the Indian plate continues its thrust beneath the Eurasian plate, it may be splitting apart beneath Tibet, separating the eastern and western halves of the slab. This fissure could have significant implications for the stability of the region, increasing the risk of earthquakes and other hazards.

The findings of the study provide an interesting and plausible explanation for the dynamic activity in this region, according to Barbara Romanowitz, a professor at the University of California, Berkeley. She also suggests that this potential split in the Indian plate may create a zone of weakness that could lead to large earthquakes.

The study proposes that the lithospheric mantle, one of the hard parts of the Earth’s crust, are sloughing off, leaving the crust behind, causing controversy within the scientific community as to how the collision of the Indian and Eurasian plates would occur or what it would mean for the Earth.

The region where this collision is occurring is unique and serves as a natural laboratory for scientists to understand the process of continental collision in real time. It is compared to a game of hide-and-seek, providing a brief snapshot of a particular process of continental collision.

Source: www.nbcnews.com

The Potential of Marine Fungi: Harnessing Water Mushrooms to Combat Antibiotic Resistance and Pollution

Microscopic marine fungi are abundant, with approximately 2000 species discovered to date.

Dayarathne MC et al. (2020)

Take a walk along the coast almost anywhere in the world and you'll see colorful patches of life growing on rocks, seawalls, and driftwood. These are lichens, a mutualistic partnership between fungi and algae. In the UK, this may include brightly colored orange marine lichens and yellowish coastal sunburst lichens, as well as many other Drabber species.

Lichens are typically thought of as terrestrial organisms, and in fact, the majority grow inland on rocks, tree trunks, leaves, and soil. However, coastal organisms are not creatures that accidentally washed ashore from land; they are marine-adapted species found only on or in close proximity to shores. Until recently, they were considered to be outliers in the almost entirely terrestrial fungal kingdom. No more. “Fungi are present in every marine ecosystem we observe,” says Michael Cunliffe of the University of Plymouth in the UK.

Research on marine fungi is currently rapidly increasing, but their exact role and importance in marine ecosystems remains a mystery. Nevertheless, there are high hopes that it could save us from the two great scourges of the 21st century: antibiotic resistance and plastic pollution.

What are marine fungi?

The existence of marine fungi has been known for many years. The earliest descriptions were published in his mid-19th century to his early 20th century, but these were largely ignored by mainstream mycologists. Most of the species discovered are found on the roots of seaweed that live near the coast.

Source: www.newscientist.com

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