Gravitational waves result from colliding black holes
Victor de Schwanberg/Science Photography Library
Researching the universe can be enhanced by AI created by Google DeepMind. With an algorithm capable of diminishing unwanted noise by as much as 100 times, the Gravitational Wave Observatory (LIGO), equipped with laser interferometers, can identify specific black hole types that are affecting our separation.
LIGO aims to detect gravitational waves generated when entities like black holes spiral and collide. These waves traverse the universe at light speed, yet the spacetime fluctuations are minimal—10,000 times smaller than an atomic nucleus. Since its initial detection a decade ago, LIGO has recorded signals from nearly 100 black hole collisions.
The experiment comprises two U.S. observatories, each with two perpendicular arms measuring 4 km. A laser is directed down each arm and bounced off precise mirrors, where an interferometer compares the beams. As gravitational waves pass through, the lengths of the arms fluctuate slightly, and these changes are meticulously documented to help visualize the signals’ origins.
However, achieving such precision is challenging, as even distant ocean waves or clouds can interfere with measurements. This noise can overwhelm the signal, rendering some observations unfeasible. To counterbalance this noise and accurately adjust the mirrors and other equipment, numerous critical tweaks are essential.
Lana Adhikari from the California Institute of Technology in Pasadena stated that his team has collaborated with DeepMind to innovate new AI methods. He mentions that even automating these adjustments can sometimes introduce noise. “That control noise has puzzled us for decades. All aspects in this space are hindered,” Adhikari explains. “How can you stabilize a mirror without creating noise? If left uncontrolled, the mirror tends to oscillate unpredictably.”
Laura Nuttall from the University of Portsmouth, UK, was involved in manually executing these adjustments at LIGO. “Changing one element causes a cascading effect; one change leads to another,” she points out. “It feels like an endless cycle of fine-tuning.”
DeepMind’s new AI, known as Deep Loop Shaping, aims to minimize noise by making up to 100 adjustments to LIGO’s mirrors. The AI is trained via simulations before being implemented in real-world scenarios, focusing on achieving two main objectives: limiting the number of adjustments it performs. “Over time, as it repeatedly operates, it’s like conducting hundreds or thousands of trials in a simulation. The controller learns what strategies work and identifies the best approach,” says Jonas Buchli from DeepMind.
Alberto Vecchio from the University of Birmingham, UK, expressed enthusiasm for the AI’s role in LIGO but mentioned that many challenges remain. The AI currently operates effectively for only an hour under real conditions, necessitating longer-term validation. Additionally, it’s only been applied to one control aspect, while many hundreds, if not thousands, of factors could assist in stabilizing the mirrors.
“This is clearly an initial step, but it’s certainly a fascinating one. There’s considerable scope for significant advancement,” Vecchio remarked.
If similar enhancements could be replicated elsewhere, it’s possible to detect medium-sized black holes—those around 1,000 times the mass of our sun—a category that has yet to see confirmed observations. Improvements are typically seen with the low-frequency gravitational waves generated by large bodies, where noise can obscure the signals.
“We’ve observed black holes up to 100 solar masses and more than a million solar masses in galaxies. What’s out there in between?” Vecchio pondered. “There’s a perception that black holes exist across a spectrum of masses, yet clear experimental evidence remains elusive.”
Nuttall commented that this new methodology could enhance identification of known black hole types. “This appears quite promising,” she stated. “I’m thrilled about this development.”
These striking images capture the efforts of photographer Nicole Tung, who dedicated nine months to documenting the human and environmental toll of overfishing in Southeast Asia. Since the 1950s, fishing has rapidly evolved from a traditional craft into a global industry, primarily in developed nations. The rise in overfishing and illegal catch practices is alarming, driven by the increasing demand from a growing population.
Tung emphasizes the significance of the region as a vital part of the global fisheries market. Her project received funding from the €50,000 Kaminyak Photojournalism Award for fieldwork, which shifted her perspective on seafood consumption. Rather than suggesting complete abstention, she advocates for greater awareness and informed choices from consumers.
She expressed her distress over harrowing accounts from Indonesian fishermen, who detailed the violence and dreadful conditions they encounter at sea.
The image above illustrates a fisherman delivering a catch of tuna at General Santos fishport in the Philippines after a month at sea, including Bigger Tuna and Blue Marlin.
Thai dock worker
Nicole Tung
In other scenes, dock workers from Myanmar sort fish species being offloaded in Ranong, Thailand. Below, the indigenous Ulak Roy people and Thai villagers from Koh Lipe gather wood from nearby islands during a festival celebrating the end of the fishing and tourism season. They utilize the materials to construct ceremonial boats as offerings to their ancestors.
Indigenous Urak Lawoi people and Thai villagers sail their boats in Thailand
Nicole Tung
In this concluding image, a family of Filipino fishermen prepares bait for their fishing line in Quezon, Palawan, Philippines.
“Even trying to explain ‘space’ feels challenging…”
ShutterStock/FastMotion
One of the most challenging aspects of writing a book is the need for authors to seek out blurbs. These endorsements, prominently featured on book covers, can entice readers to make a purchase. Right now, I’m at this stage with The Edge of Spacetime, reaching out for letters of recommendation, asking people to read my work and share positive thoughts in return for something more than just my good intentions.
It’s a bit nerve-wracking, yet it can also be fascinating. Those whose endorsements get published were asked in a specific format—what prompted you to use “space-time” with a hyphen rather than “spacetime”?
This seems like a question of simple grammar, but there’s a deeper issue at play. When discussing space or time individually, we have an intuitive grasp of what we mean. The term “space-time” is somewhat newer to scientific discourse. Historically, many cultures have embraced a unified concept that doesn’t differentiate between space and time as distinct entities.
For me, as a science communicator, explaining this concept is quite challenging. Even articulating “space” is complex. I might say space is where movement occurs, but movement also happens within time. I could define space as the realm where things exist, but a similar statement can be made for time. We even pondered describing space as a geographical location, yet that sounds overly academic and abstract. Essentially, we are referring to a site of spatial dimensions.
To elucidate, there are three dimensions of space and one dimension of time, but time only flows in one direction.
However, as Albert Einstein famously asserted, these aren’t separate phenomena. Observers moving at varying speeds, especially as they approach the speed of light, may disagree on when certain events transpire. They may also hold differing views on the size of objects. To truly understand everything, we must quantify space-time rather than merely space or time. This perspective might not feel intuitive, but it is the most effective way to comprehend the mechanics of the universe.
In this regard, it’s worth considering whether space-time represents a confluence of two familiar phenomena or signifies the emergence of something entirely new. This is where the nuances of grammar reflect our scientific understanding, at least from my viewpoint.
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It’s worth considering whether space-time is a merger of two familiar phenomena or something new. “
My last name includes the very first hyphen I encountered. My parents chose to keep both surnames, so to me, Prescod Weinstein signifies both identities.
The hyphenated version of space-time can be interpreted as indicating that what we discuss encompasses both space and time. Conversely, removing the hyphen to form “spacetime” may suggest we are addressing an entirely distinct entity. It embodies attributes of both space and time while existing as a separate third entity.
Are we contemplating something that is both space and time (space-time), or are space and time merely approximations of a fundamentally different conception of space-time? I find myself somewhat ambivalent. In my earlier book, The Blurbriter, I noted this distinction without employing hyphens, thus raising the question of why I chose to make a switch this time around.
The straightforward answer is that the title of the new book appears in the introductory sections of classic cosmology texts. Large-Scale Structure of Space-Time by Stephen Hawking and Father George Ellis states in the very first chapter that solving the equations that describe the universe “in a sense, involves contemplating the edges of space-time.” Just two pages later, they posit that locations where equations deconstruct (like at the heart of a black hole) can be viewed as “representing part of the edge of space-time.”
My book includes chapters that elucidate the types of equations they reference and the role of boundaries and edges in physics. Since I was about to borrow this phrase for my book’s title, I felt compelled to adhere to their terminology.
This is a surface-level explanation. However, at a deeper level, I am unsure where I stand. Like my request for endorsements, I feel inclined to prefer “spacetime” without a hyphen. Yet, I’m also aware of how habitual language can be, given my repeated use of hyphens in the subtitles of my previous work. Scientifically, I lean toward the notion that “space-time” encompasses both space and time, asserting that it is an entirely different fourth dimension: space-time. This may seem like a complex perspective, but I desire to embrace both aspects simultaneously!
Chanda’s Week
What I’m reading
I’m quite excited about the new Charlie Jane Anders novel Lessons from Magic and Disaster.
What I’m seeing
I’ve just caught up with the sci-fi series Invasion, and it’s truly captivating.
What I’m working on
I have a new postdoctoral researcher joining my group.
Chanda Prescod-Weinstein is an associate professor of physics and astronomy at the University of New Hampshire. She is the author of Cosmos with Disabilities and her forthcoming book, Edges of Space-Time: Particles, Poetry, and the Dreams of the Universe.
Following the Cretaceous Mass Extinction, ancient penguin relatives rapidly diversified
Mark P. Witton/Science Photo Library
Four newly discovered fossil species in New Zealand demonstrate the significant diversity of early penguins, characterized by their long, dagger-like beaks for catching prey.
The latest findings provide “an unexpected insight into the early evolution of penguins,” states Gerald Mayle at the Senckenberg Research Institute in Germany.
The fossils were unearthed from the Waipara Greensand Formation in Canterbury, New Zealand, a region recognized for flourishing after the mass extinction that eradicated non-avian dinosaurs, preserving some of the early avian species that diversified.
“A notable aspect of ancient New Zealand is the lack of terrestrial predators, which enabled early penguins to lose their ability to fly,” explains Mayle. This absence of predators might also clarify why certain early penguins reached sizes as large as humans, he remarks.
In total, Mayr and colleagues detailed four new species, showcasing a remarkable variety of shapes and sizes. Many fossils reveal previously unknown skeletal characteristics; one specimen boasted an exceptionally long back toe, along with an incredibly intact skull and beak.
“Fossils with beaks that provide insight into avian diets are exceedingly rare among penguins from earlier epochs [23 million years ago],” says Tatsuro Ando, who was not part of the study at the Japanese Paleontology Museum.
Present-day penguins feature varied beak shapes tailored to their specific prey, which can include krill and small fish, as well as invertebrates like squid, Ando explains. While these beaks can be short, thick, or curved, they do not compare to those seen in early penguins.
“It appears that ancient penguins utilized their long beaks to grasp their prey,” says Mayle. After impaling the fish, they likely surfaced to toss it into the air and catch it, he adds.
Over a span of approximately 20 million years, penguins evolved to lose their elongated, slender beaks. This change was likely an adaptation to prolonged underwater periods. As they transitioned to a more aquatic lifestyle, their feeding strategies and beak structures also evolved.
The newfound fossils underscore the significance of New Zealand as a “cradle of penguin evolution,” remarked Mayle, indicating that the earliest penguins diversified and spread globally to regions including New Zealand, Antarctica, South Africa, and South America.
The 20th century was a vibrant era for future visions, yet the 21st century has not sparked the same enthusiasm. Sci-fi author William Gibson, known for his groundbreaking cyberpunk work Neuromancer, refers to this phenomenon as “Future fatigue”, suggesting we seldom mention the 22nd century.
This stagnation is partly due to the evolution of many iconic future concepts from the 20th century. For instance, plastic was once hailed as the material of the future. Although it has proven to be durable, versatile, and plentiful, its properties now pose significant environmental and health concerns.
Today’s predominant future imagery carries a legacy of historical influence. Themes such as space colonization, dystopian AI, and a yearning for an imaginary past persist, often shaped by the climate anxiety many people experience. The future begins to feel like a closed book rather than an open road.
Jean Louis Missica, former vice mayor of Paris, articulated it well in his writing: “When the future is bleak, people idealize past golden ages. Nostalgia becomes a refuge amid danger and a cocoon for anticipated decline.”
Another factor contributing to this stuck imagery is social media, which exposes users to a vast array of different time periods at once, fostering nostalgia and a continuous remixing of existing ideas.
However, new visions of the future have emerged this century. For example, the climate aspiration movement gained traction on Tumblr and blogs in the 2000s. Yet, as smartphones became our primary mode of communication, the collective imagination surrounding our vision of the future waned.
I reflect on the future of living, drawing from my experience that a cohesive vision can motivate individuals to drive change. Such visions serve as engines of inspiration and imagination. They enable us to envision the society we aspire to create and commit to working towards that future. Movements like Civil Rights have long recognized this. A unified future vision also manifests effectively in architecture, advertising, and television, with Star Trek inspiring engineers for decades.
As we transition from fossil fuels to renewable energy, we find ourselves in a transformative era. This period is daunting yet invigorating. Numerous hotspots of innovation are emerging, such as rooftop solar energy in Pakistan, where households and small businesses actively adopt renewable energy solutions, or the global initiatives like Transition Town, rethinking local economies and cultures.
Nevertheless, we lack a unified vision that integrates these innovations, embedding them within a social context and building pathways from the present to the future.
In my new book, I explore four visions for the future currently taking shape: DeGrowth, which reevaluates our economic roles; SolarPunk, which revitalizes cultural innovation; the Metaverse, which immerses us in a vibrant digital universe; and movements that encourage us to rethink our relationship with nature.
Yet, the future won’t stop evolving. We must cultivate and nurture more emerging visions, allowing them to take shape as we redefine our narrative of what the future could be.
Psychoanalysts Can Aid Couples in Clarifying Relationship Concerns
Carl Navarro Percesus/Getty Images
Labour of Love Stephen Grosz (UK: Chatto & Windus, Available Now; US: Random House, February 10, 2026)
Psychoanalysts, with their deep understanding of human emotions, might seem to enjoy relationships devoid of the tumult that often impacts our romantic endeavors.
However, in his compelling memoir, Labour of Love, Grosz delves into over 40 years of discussions about love with his patients, observing the intricate web involving four of his colleagues. At first, Susan and Paul appear to be a blissfully married couple, just like Kora and Martin, until it’s revealed that Paul and Kora have maintained a secret affair for two years.
The ensuing critique strikes at the very essence of their profession. “I’ve never fully grasped what it means to be a psychoanalyst,” Susan confides to Kora. “I possess empathy, I care for others, I establish boundaries, I perceive reality. Avoid taking your friend’s husband.” For Susan, psychoanalysis seems to focus on accountability and self-regulation. Kora, on the other hand, believes her journey is about achieving complete self-awareness. To her, psychoanalysis serves the purpose of intentional self-discovery.
Grosz reflects on these paradoxes, arriving at ambiguous conclusions. He suggests that while psychoanalysis may target both objectives, neither should be a primary aim. “It benefits the patient and enhances her well-being. However, these goals may obscure the hidden desire to restrict the patient’s freedom,” he states. Psychoanalysts enable their patients to gain insights into their minds, but how they utilize that understanding remains their own decision.
Skeptics might contend that psychoanalysis lacks scientific validity. After all, how can one measure the effectiveness of interventions on mental processes? Initially pioneered by Sigmund Freud, psychoanalysis employs informal dialogues to uncover unconscious dynamics, often involving extended discussions that may last for years, including in-depth explorations of childhood. This contrasts sharply with cognitive behavioral therapy (CBT), which utilizes specific exercises aimed at altering immediate thoughts and behaviors, such as more aggressive strategies to “reconstruct” experiences.
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Grosz has drawn comparisons to Anton Chekhov and Oliver Sacks. “
Nowadays, CBT is often the preferred initial treatment for various mental health issues, yet clinical trials indicate that psychoanalysis effectively enhances well-being. Labour of Love offers a captivating exploration of this process through the stories of Gross’s patients and acquaintances.
Take Sophie, for example. When Gross first meets her, she’s engaged, but despite her hopes for a future marriage, she hesitates to send out any invitations. She is plagued by haunting dreams about her parents’ demise. Together, they eventually trace this fear back to her parents and their loss, which occurred before Sophie was born. She dreads any changes that might separate her from them.
Often, individuals’ issues stem from a fear of losing their identity. “A crucial distinction exists between surrendering to something (or someone) and submitting to it,” Gross asserts. Submissions equate to transactions and involve relinquishing control, whereas mutual surrender fosters vitality, empowerment, and acceptance. In that space, love can flourish.
The journey to comprehend Labour of Love is not straightforward. As the title implies, understanding both ourselves and our beloved requires consistent effort.
Grosz is a compelling writer whose thoughtful narratives frequently illuminate the complexities of human experiences. A review of his earlier work, Researched Life, likened him to literary figures such as Anton Chekhov and Oliver Sacks. His storytelling shines particularly when illustrating the intertwined lives of fellow psychoanalysts. For instance, during Cola’s death, Paul connects deeply with Cola’s family while sitting shiva. In this poignant moment, he finds solace in Susan’s presence.
This scene encapsulates the contradictions inherent in love, as Grosz elaborates: “Susan and Paul loved, resented, married, and divorced. Yet, even during this challenging period, they remained a couple. Their love continued to evolve.”
David Robson is the author of The Law of Connection: 13 Social Strategies That Transform Your Life
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Dan Berman, International Brain Research Institute
The initial comprehensive activity map of the mammalian brain has unveiled groundbreaking revelations regarding decision-making processes.
For many years, neuroscientists aspired to capture neuronal activity throughout the brain at an individual level. However, challenges persist, including the limitations on the number of neurons an electrode can record, the number of electrodes deployable in a single brain, and the number of animals that a solitary lab can study.
To address these hurdles, a collaboration among 12 laboratories is underway, with each conducting identical experiments and recording duplicates to ensure consistency in collected data. This joint effort, tracking the activity of over 650,000 neurons, has resulted in the first comprehensive brain activity map related to complex behaviors.
“This research exemplifies a novel approach to addressing intricate inquiries in contemporary neuroscience,” stated Benedetto de Martino of University College London, who was not a part of this study. “Similar to CERN, which unites physicists to tackle profound issues in particle physics, this project will bring together global laboratories to confront challenges too expansive for individual teams.”
In each facility, mice were trained to maneuver a small LEGO steering wheel to direct a striped target towards the center of the display. The target was easily distinguishable when the stripes contrasted sharply. As contrast dwindled, the target nearly vanished, compelling the mice to rely on prior knowledge to respond accurately for a reward.
Bias was factored into the experiment, impacting the mice’s expectations about the target’s location. For instance, it could appear on either side of the screen. When the bias was inverted, the mice adjusted their expectations accordingly.
The resulting activity map indicates that decision-related processes are dispersed throughout the brain, rather than localized in one specific area. “Many assertions claimed, ‘this region is responsible for this function.’ However, our findings reveal that decision-making involves numerous regions collaborating through a consensus,” remarked team member Alexandre Pouget from the University of Geneva, Switzerland.
Furthermore, the findings support earlier research indicating that decision-related signals form long before an action is executed. Pouget noted that even prior to the commencement of individual experiments, signals linked to forthcoming decisions are evident. These signals accumulate when the target is presented, prompting the mice to move the wheels until a threshold is reached.
The second study reveals that beliefs regarding the target’s position are encoded very early in the brain’s activity. Researchers discovered that whether the signal emerged from the eye or journeyed to the thalamus, the brain’s relay center, advanced expectations regarding the target’s left or right positioning were already established.
This suggests that from the moment sensory information is processed by our brains, it is inherently influenced by knowledge, altering the conscious decision-making process unconsciously, according to Pouget. “While speculative, this may align with what we interpret as intuition,” he added.
Interestingly, the encoding not only captures recent sensory experiences but also seems to document the recent history of choices made. Lawrence Hunt from Oxford University pointed out, “This indicates that our actions and subjective experiences shape our perceptions, rather than the true objective reality.”
Does this imply our decisions are predestined? “The brain and its environment operate as a deterministic system. People often resist this idea, but it is accurate,” Pouget stated. “This means one can predict, to an extent, what actions will be taken before a decision is made. Nevertheless, when new information arises, expectations must be recalibrated, remaining unaware of how the surrounding world will evolve,” he explained.
Looking ahead, researchers are optimistic that the findings and collaborative methodologies will enhance the understanding of conditions like autism. A mouse model of autism suggests these animals struggle to update previous expectations with new information, according to Pouget, which resonates with our behaviors and perceptions.
Male ants of distinct species laid by the same mother: Messor ibericus (left) and Messor structor (right)
Jonathan Romiguier
In the clutches of the Iberian Harvester Ant queens, another male species, the Builder Harvester Ant, emerges. These males are responsible for siring all the workers in the colony.
“This assertion appears utterly unbelievable, akin to the impossible,” remarks Jonathan Romiguier from the University of Montpellier, France. Nonetheless, he has confirmed its validity.
Romiguier’s curiosity was piqued by the Iberian harvester ants (Messor ibericus) after he discovered that all the workers were hybrids. About half of their DNA aligned with that of the builder harvester ant (Messor structor).
The most plausible explanation is that the queen of M. ibericus mated with a male of M. structor. This occurrence is seen in other ant species. The reasons remain unclear, but two main theories have emerged. One is that hybrids of closely related species could benefit from what’s known as hybrid vigor, where various genes can compensate for each other’s deficiencies.
Another theory suggests this may address a peculiar challenge faced by M. ibericus and several other harvester ant species: whenever M. ibericus queens mate with males of their own species, all offspring become queens. This might stem from a genetic tendency to secure their lineage, but it becomes detrimental for colonies that need worker ants for survival. Breeding with another species may provide a solution.
However, M. ibericus colonies are widespread across various Mediterranean locales, unlike M. structor colonies, which are exclusive to Sicily. Nonetheless, Romiguier and his team encountered peculiar, hairless males of M. structor within an M. ibericus nest. So, where did they originate?
The genetic examination of these unusual males yielded perplexing insights. A tiny segment of the mitochondrial DNA—passed solely from the mother—indicated that these males derive from the M. ibericus queen.
This hinted that the eggs produced by the queen of M. ibericus could encompass males of a different species. To verify this theory, Romiguier brought several M. ibericus colonies into his lab. “Under laboratory conditions, it’s nearly impossible to find a male,” he comments. “We maintained about 50 colonies and observed one male for two years without success. Then, fortune smiled upon us.”
From three M. structor males born in the lab, the evidence was undeniable: the queen of M. ibericus produced males from both species. The only explanation for this phenomenon is that the queen ant cloned M. structor males using stored sperm in specialized organs called spermathecae. The resulting eggs were almost entirely devoid of M. ibericus DNA, except for its mitochondrial component.
This also clarifies the origin of M. structor sperm: by producing two types of males, the queen guarantees that her daughters who evolve into queens can mate with both male types. The females use M. ibericus sperm to generate new queens, while M. structor sperm is utilized for hybrid workers and new male ants.
There are notable instances from other species—including ants, mollusks, and stick insects—where female eggs are manipulated by male sperm from different species, leading to the elimination of egg DNA and the production of unrelated individuals. However, this scenario mainly benefits males. This is the sole known instance where both male and female offspring from distinct species rely on each other for reproduction.
“The queen of M. ibericus is entirely dependent on her cloned males. Without them, she cannot produce workers,” states Romiguier. Moreover, the clones of M. structor need the males of M. ibericus for rearing workers and sustaining their colonies—there is no sign that they mate exclusively within their species.
While these findings may seem far-fetched, they have garnered the support of other specialists. “The researchers conducted thorough investigations into these ants,” comments Nathan Law from the University of Sydney. “Their results robustly affirm their conclusions.”
He speculates that cloned males could accumulate harmful genetic mutations that may not be purged over time due to the lack of interbreeding with other strains. “Eventually, this system may start to decline, especially as environmental conditions shift.”
Romiguier agrees that this exceptional situation might eventually lead to collapse. Yet, at present, it appears that M. ibericus and M. structor have navigated their relationship with ingenious adaptability, propelling their expansion throughout the Mediterranean, while M. structor colonies have not established themselves elsewhere.
Insects and Ecosystem Expedition Safari: Sri Lanka
A voyage into the depths of Sri Lanka’s vast biodiversity through a unique entomology and ecosystem-centered expedition.
Icelandic geothermal power facilities engaged in the underground injection of carbon dioxide for extended storage
sigrg/carbfix
Recent studies indicate that the planet may exhaust its capacity for storing captured carbon dioxide within the next 200 years, revealing that our ability to retain CO.2 underground is significantly less than previously believed.
Government and industry advocates promote the underground storage of carbon dioxide as a viable solution to achieving net-zero emissions while still utilizing fossil fuels.
Previously estimated industry figures suggested a global geological storage capacity of about 14,000 Gigatonnes of CO.2. However, as noted by Jori Rogelj from Imperial College London, UK, this capacity was thought to be effectively limitless.
Through comprehensive analysis, Rogelj and his team discovered that the actual available storage space might be considerably lower. By assessing stable geological formations while excluding areas with significant risk factors, such as proximity to major urban centers, sensitive ecosystems, or regions prone to earthquakes, they concluded that only 1460 Gigatonnes of geological storage capacity is viable worldwide.
“From a situation where storage options appeared virtually boundless, we’ve transformed our perspective,” Rogelj explains. “The storage potential we can depend on requires careful management and represents a crucial asset,” he continues, emphasizing that the potential is now ten times more valuable than previously recognized.
Most climate projections indicate that adequate underground carbon storage is essential for the world to attain net-zero emissions. The extent of this storage relies fundamentally on reducing fossil fuel consumption. Researchers caution that if we continue to depend on geological storage to isolate significant emissions post-net zero, we could deplete carbon storage entirely by the year 2200.
Rogelj asserts that his findings suggest underground carbon storage should only be utilized as a last resort when all other options have been exhausted. He recommends relying on zero-emissions solutions whenever feasible, rather than capturing and storing emissions from fossil fuel power stations.
This strategy would preserve underground storage capacity for CO2 that could be utilized with technologies such as direct air capture (DAC), which extracts excess CO2 directly from the atmosphere. DACs, along with other “negative emissions” technologies, can potentially help the world achieve net negative emissions beyond reaching net zero, opening up pathways to effectively reverse climate change.
According to Rogelj and his colleagues, the 1460 Gigatonnes of accessible underground CO2 storage capacity could allow the world to counteract warming by as much as 0.7°C.
Nonetheless, Stuart Haszeldine from the University of Edinburgh warns that the actual usable geological storage capacity might be less than the industry’s 14,000 Gigatonnes estimate and suggests that these revised lower figures could still be overly optimistic.
He argues that the team’s approach to evaluating risk factors is “quite conservative,” pointing out that certain seismic regions, such as the North Sea, have been excluded from consideration but remain suitable for carbon isolation. “We understand enough about carbon storage and oil reserves. An oil field filled with oil, gas, or carbon dioxide can withstand quakes of magnitude 6 without any issues,” Haszeldine states.
He emphasizes that most analysts foresee carbon sequestration as an integral part of the transition away from fossil fuels. Therefore, he predicts that the volume of carbon injected underground yearly should diminish once net-zero emissions are achieved.
“[Carbon capture and storage] encompasses a wide range of climate pessimism and challenges, which have often been overlooked, explaining why we don’t really require a tremendous amount of joint CO2 storage capacity,” Haszeldine concludes.
It may be wise to keep your phone out of the bathroom
Ekaterina Demidova/Getty Images
Do you find yourself using your smartphone while on the toilet? If that’s the case, you might be spending more time there than anticipated, which could increase your risk of bleeding by nearly 50%.
“Our gastroenterologists consistently advise patients, ‘Limit your time in the bathroom,'” says Trisha Pasricha from Beth Israel Deaconess Medical Center in Boston, Massachusetts. “However, upon exploring the literature, I discovered substantial data backing this advice.”
Pasricha and her team are currently conducting their own study, asking 125 individuals scheduled for colonoscopy to complete a questionnaire regarding their bathroom habits, overall health, and physical activity. They then analyze the colonoscopy images to check for signs of bleeding, also referred to as a mass in the lower region.
“These conditions can be quite challenging for individuals to identify on their own,” Pasricha explains. “Sometimes they are internal and may not be felt, and what may be perceived externally doesn’t always correlate with actual bleeding.”
Among participants over 45, two-thirds reported using their smartphones in the bathroom. “If we surveyed college students, I suspect almost no one would skip bringing their phones to the restroom,” Pasricha remarked.
The study revealed that 37% of individuals who used smartphones in the bathroom averaged five or more minutes spent in there, whereas only 7% of non-users spent the same duration. Thus, phone users were about five times more likely to linger for five minutes or longer.
However, most participants seemed unaware of this, with only 5% acknowledging that smartphone usage extended their time spent in the bathroom. The data did not show any significant correlation between the participants’ gender and the time spent on the toilet.
After adjusting for age and physical activity levels, the research team concluded that smartphone use in the bathroom correlated with a 46% increase in bleeding risk. “It’s important to clarify that our study doesn’t establish a cause-and-effect relationship,” Pasricha noted. Moving forward, future research will involve interventions, asking some participants to refrain from using their phones while in the restroom.
The research also found no connection between tension and bleeding risk. This might seem surprising given common beliefs; however, the existing evidence is quite limited. In fact, some studies have indicated that the risk of bleeding correlates more with diarrhea rather than constipation.
Pasricha’s research suggests that the main risk factor is the prolonged time spent seated on the toilet. The consensus is that this position offers less pelvic support compared to sitting on a flat surface. “This leads to a passive rise in pressure affecting these muscles due to the lack of pelvic floor support,” she explained.
Lucinda Harris at the Mayo Clinic in Arizona agrees, noting that long durations in the bathroom can mimic the pressure experienced during pregnancy in the pelvic region.
If these findings hold true, the widespread use of smartphones might be contributing to increasing rates of bowel issues globally. Diagnosing such conditions can be tricky, so it remains unclear if the incidence rates are truly changing, Pasricha pointed out. Additionally, dietary changes could also be influencing these rates.
Pasricha advises keeping your smartphone outside the bathroom, although reading materials that aren’t designed to be addictive might be acceptable. “Consider reading things that promote moderation, and keep track of your time,” she suggested. Financial Times
Only 0.3% of the Earth’s land area needs solar panels to fulfill all energy requirements
VCG via Getty Images
Solar energy has been gaining traction for years, and it’s easy to see why. It represents one of the most economical ways to produce energy almost anywhere and stands as a vital measure against climate change.
However, there are skeptics. U.S. Energy Secretary Chris Wright asserts that solar energy cannot meet global energy demands. Many experts highlight that this claim is fundamentally misguided. Over time, sunlight—along with wind energy—offers the only reliable power source capable of satisfying escalating energy demands without harming the planet.
On September 2nd, Wright posted on social media platform x, stating, “Even if we covered the entire planet with solar panels, it would only generate 20% of the world’s energy. One of the greatest mistakes politicians make is equating electricity with energy!”
First and foremost, electricity is quantified based on the energy it delivers, making it practical to consider electricity as equivalent to energy.
Climate scientist Gavin Schmidt from NASA’s Goddard Space Research Institute remarked on Bluesky that the total energy content utilized by all fuels globally in 2024 was approximately 186,000 terawatt hours. He emphasized that the Earth receives 6,000 times that amount in energy each year.
Moreover, Schmidt noted that since 60% of fossil fuel energy is typically wasted in the conversion process to usable electricity, the Earth receives 18,000 times more energy than is needed to satisfy current energy consumption levels.
While existing solar panels only capture around 20% of available solar energy and can’t be installed everywhere, a 2021 report by Carbon Tracker estimated that merely 0.3% of the world’s land area (limited to land) is required to address current energy needs through solar energy alone. This footprint is smaller than that of existing fossil fuel infrastructure. In essence, the report indicates that solar and wind can provide over 100 times the current global energy demand.
We are fortunate, as the current reliance on fossil fuels is already contributing to hazardous climate change with fossil fuels alone supplying 100 times more energy than the planet can sustainably handle. But what about nuclear fusion? If it becomes a feasible option, would it surpass solar energy?
The answer is negative. Eric Chaisson from Harvard University anticipates minimal growth in global energy demand; however, the waste heat generated could potentially elevate global temperatures by 3°C within three centuries. This refers to waste heat from everyday activities like boiling a kettle or using a computer, which consumes the energy produced.
Solar energy—along with wind, tides, and waves—functions fundamentally as a source harnessed from the sun, rendering waste heat irrelevant. The energy we utilize, whether it ends up as waste heat or not, determines its practical value. In contrast, other energy sources, like nuclear fission, do not currently address waste heat management.
“[Carl] Sagan preached to me, and I now relay that message to students. Any planet must ultimately utilize the energy it possesses,” Chaisson remarked in an interview with New Scientist in 2012.
Though three centuries is a long time, the implications of waste heat are already significant. Studies indicate that maximum temperatures in Europe’s summers have increased by 0.4°C. By 2100, average annual temperatures in certain industrialized regions may rise by nearly 1°C due to waste heat—effects not currently considered in climate models.
Ultimately, the only technology that can sustainably harness solar and wind energy to meet global energy demands for centuries, without triggering catastrophic warming, is these renewable sources. The projections couldn’t be more misguided.
Plant-based and meat kibbles might both be deficient in crucial nutrients
Snizhana Halytska/Alamy
To ensure a balanced diet, vegetarian and vegan dog foods need specific adjustments.
Research indicates that meat-free dry kibble fulfills dogs’ protein and fat needs but is typically short on iodine and vitamin B. With the right supplements or improved commercial options, plant-based dog foods can maintain pets’ health while minimizing the ecological footprint of the pet food industry Rebecca Broseyk from the University of Nottingham, UK.
“Provided they get all necessary nutrients from their food, dogs will thrive,” she explains.
Many vegans and vegetarians who have dogs often grapple with the ethics of feeding meat to carnivorous pets David Gardner at the University of Nottingham. In light of this concern, manufacturers are beginning to offer plant-based options.
Organizations such as the European Federation of Pet Food Industry and the American Association for Feed Management are advocating for standardized assessments of commercial pet foods and additives to guarantee nutritional adequacy. Nonetheless, most pet foods globally lack thorough nutritional evaluations by independent experts, according to Gardner.
Brociek, Gardner, and their team examined 25 types of commercially available dry foods for healthy adult dogs, of which 19 were formulated with either meat or plants. Among these, two were labeled vegetarian and four were vegan.
Researchers assert that although marketed as nutritionally complete, none of the official dog dietary guidelines were entirely met. However, all foods did manage to provide appropriate levels of protein, fatty acids, and essential amino acids.
The majority, including five out of six plant-based options, fell short on iodine, although seaweed served as a beneficial remedy for these deficiencies.
The vitamins were generally sufficient, except for vitamin B, which was especially deficient in plant-based options. Dogs lacking vitamin B can experience skin, nerve, and digestive issues, suggesting that manufacturers should bolster their formulations, the researchers state.
The results indicate a need for oversight in dog food production across all types, not just those that are plant-based. Andrew Knight from Murdoch University, Australia, stresses, “Consumers expect that if a product claims to be nutritionally healthy, it should be accurate, but that’s often not the case.”
“A vegetarian diet can be beneficial if nutrients lacking in plant sources are adequately replaced, similar to the considerations for humans choosing vegetarian diets,” says Lucia Casini from the University of Pisa, Italy, who adds that pet owners should refrain from making their own plant-based meals for their pets.
Dogs have evolved to consume a variety of foods, so a well-rounded plant-based diet can fulfill their nutritional needs, which can also lower the environmental impact associated with meat production, including greenhouse gas emissions, according to Gardner.
“They are genuine omnivores,” he remarks. “As many Labrador owners (myself included) will attest, they will eat just about anything.”
While someone in their 70s didn’t serve in World War II, this statement holds truth, as even the oldest Scepter Agerians were born post-war. Yet, a cultural link persists between this demographic and the era of Vera Lynn and the Blitz.
When discussing parents and technology, similar misconceptions arise. The prevailing belief is that social media and the internet are a realm beyond the understanding of parents, prompting calls for national intervention to shield children from tech giants. This month, Australia plans to outline its forthcoming restrictions. However, the parents of today’s teens are increasingly digitally savvy, having grown up in the age of MySpace and Habbo Hotel. Why have we come to think that these individuals can’t comprehend how their kids engage with TikTok and Fortnite?
There are already straightforward methods for managing children’s online access, such as adjusting router configurations or mandating parental approval for app installations. Yet politicians seem to believe these tasks require advanced technical skills, resulting in overly broad restrictions. If you could customize your Facebook profile in college, fine-tuning some settings shouldn’t be beyond reach. Instead of asking everyone to verify their age and identity online, why not trust the judgment of parents?
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If you customized your Facebook page in university, you should be able to tweak a few settings “
Failing to adapt to generational shifts can lead to broader issues. Like veterans who narrowly focus on historical battles from the past, there’s a risk of misdirecting attention. While lawmakers clamp down on social media, they’re simultaneously rushing to embrace AI technologies that rely on sophisticated language models, which significantly affect today’s youth, leaving educators pondering how to create ChatGPT-proof assignments.
Rather than issuing outright bans, we should facilitate open discussions about emerging technologies, encompassing social media, AI, and their societal implications while engaging families in the conversation.
Recent research indicates that the ability to safely store carbon is significantly lower than earlier estimates, being only a tenth of what was initially predicted. This finding constraints its viability as a solution to the climate crisis.
New estimates, published in Nature, reveal that carbon capture could lower global warming by just 0.7°C, a stark contrast to the previously estimated 6°C.
Carbon Capture and Storage (CCS) involves capturing carbon dioxide (CO)2 from the environment or industrial processes, transporting it, and storing it deep underground to prevent greenhouse gas emissions.
The study cautions that many areas once considered suitable for CCS may pose significant risks. Concerns such as leaks, seismic activity, and water contamination could render numerous potential sites unsafe.
The researchers conducted an extensive analysis of local mapping areas for viable carbon storage locations. Their findings suggest that, in reality, CCS can store only about 146 billion tonnes of CO.2, approximately 10 times less than previously thought.
“Carbon storage is often framed as a solution to the climate crisis,” stated the lead author, Matthew Guido, a senior researcher at IIASA and the University of Maryland, USA. “Our findings indicate that its effectiveness is limited.”
“With current trends hinting at a potential rise of up to 3°C this century, even maximizing the available geological storage won’t suffice to limit warming to 2°C.”
Co-author Jori Rogelgi, a senior researcher and director at the Grantham Institute, emphasized that carbon storage should not be perceived as an endless solution for climate preservation.
“Instead, geological storage sites should be viewed as a precious resource that must be managed responsibly to ensure a safe climate future for humanity,” he remarked. “It should be employed to halt and counteract global warming rather than wastefully offset ongoing, preventable CO.2 emissions.”
Trees naturally absorb carbon, while carbon storage technology responsibly hides carbon deep underground – Credit: A. Martin UW Photos
The study also suggests that nations like the US, Russia, China, Brazil, and Australia, as major fossil fuel producers, might benefit from utilizing depleted oil and gas fields for carbon storage.
“This issue transcends mere technology,” remarked co-author Siddharth Joshi, a research scholar at IIASA. “It encompasses concepts of transgenerational and national justice.”
“Countries with the highest historical emissions should lead in utilizing this resource wisely as they hold the most practical carbon storage options.”
Experts not involved in this research are currently debating the accuracy of the paper’s figures and their implications for the future of carbon storage as astrategy to mitigate the climate crisis.
However, Professor Carrie Leah, a climate scientist at Cardiff University who was not part of the study, stated that the finite nature of carbon storage should redirect focus towards reducing fossil fuel usage.
“There is no solitary solution to climate mitigation,” Leah noted. “It’s akin to a pie comprised of multiple slices.
“This study illustrates that the CCS portion of the pie is significantly smaller than previously believed, highlighting the urgent need to address the larger slices of fossil fuel reduction.”
The latest study presents paleoenvironmental models indicating how tidal dynamics played a crucial role in the early evolution of Sumerian agriculture and sociopolitical intricacies.
Cylinder seal impression from the Uruk era circa 3100 BC. Image credit: Louvre Museum.
The earliest known network of city-states, intricately linked by common cultural practices and economic ties, emerged in southern Mesopotamia approximately 5,000 years ago.
The prosperity of this urban center, collectively referred to as Schmer, was fundamentally based on agriculture, supported by extensive irrigation systems.
The urbanization of Schmah, following the long-standing rural Ubaid culture, was part of a process that began at least prior to the millennium during the Uruk period (6,000-5,200 years ago).
The concurrent rise in population, innovation, and professional specialization during this time led to the formation of a state system with a complex economy, interlinking urban centers with their rural surroundings.
This “Sumerian takeoff” could not have happened in the challenging, arid tropical region between the Arabian and Iranian deserts without access to the perennial freshwater provided by the Euphrates and Tigris rivers.
However, questions remain about how, and when, labor-intensive large-scale irrigation became prevalent in the area, and how the abundance of water transformed into social prosperity.
“Our findings indicate that Sumer was literally built upon the rhythm of water, culturally,” states Dr. Lviv Giosan, a researcher at Woods Hole Marine Facilities.
“The cyclical tidal patterns and the morphodynamics of deltas—how landscapes evolve over time due to dynamic processes—were intricately woven into Sumerian mythology, innovation, and daily life.”
This research reveals that between 7,000 to 5,000 years ago, the Persian Gulf was expanding inland, with tides pushing freshwater into the lower Tigris and Euphrates twice daily.
Scholars propose that early communities harnessed this reliable hydrology through short canals to irrigate crops and cultivate dates, allowing for high-yield farming without the need for vast infrastructure.
As the river created a delta at the bay’s head, tidal access to the interior was obstructed.
The subsequent loss of tidal influence may have sparked ecological and economic crises, necessitating a significant social response.
The extensive efforts for irrigation and flood management that followed ultimately characterized Schmer’s golden age.
Dr. Reed Goodman, a researcher at Clemson University, remarked:
“The Mesopotamian delta was distinct. Its constantly shifting land spurred some of the earliest intensive agriculture in history and led to ambitious social experiments, driven by that restless land.”
In addition to environmental factors, this study also investigates the cultural impact of this aquatic foundation, linking Mesopotamia to the Sumerian pantheon’s flood myth.
“The key conclusions of this research highlight what we discovered in Ragash,” notes Dr. Holly Pittman, director of the Ragash Archaeology Project at the Penn Museum.
“Rapid environmental changes fueled inequality, political integration, and the ideology of the world’s first urban societies.”
Leveraging ancient environmental and landscape data, new samples from historic Ragash archaeological sites, and detailed satellite imagery, the authors reconstructed what Sumerian coasts may have looked like long ago and envisioned how its inhabitants adapted to their ever-changing environment.
“Our work underscores both the opportunities and risks associated with social transformation in response to significant environmental crises,” Dr. Giosan added.
“It is always fascinating to uncover genuine history hidden within mythology, and interdisciplinary research like ours plays a crucial role in revealing it.”
Daily vaccinations for hepatitis B are administered worldwide
Mehmet Salih Guler / Getty Images
The hepatitis B vaccine not only prevents infection but also appears to lower the chances of developing diabetes.
In most countries, infants receive this vaccine routinely, typically as part of a three-dose series. In the US, it was incorporated into vaccination schedules in 1991. By 2018, around 30% of adults were fully vaccinated.
However, earlier studies didn’t investigate whether vaccination could lower diabetes risk in individuals who were not infected with hepatitis B.
To address this gap, Nhu-Quynh Phan from Taipei Medical University in Taiwan and her team examined health data from over 580,000 people across the US, Europe, Africa, Latin America, the Middle East, and Asia-Pacific. These records averaged almost four years for each individual, covering the period from 2005 to 2023.
Participants aged 18 to 90 had no types of diabetes and were not infected with hepatitis B. About half were vaccinated, determined by measuring virus-specific antibodies in their blood.
The study revealed that diabetes prevalence among vaccinated individuals was 15% lower than in the unvaccinated group, with most cases being type 2 diabetes, the most prevalent form. The findings will be shared at the upcoming annual meeting of the Diabetes Association in Vienna, Austria.
This observational study also indicated a dose-response correlation. Participants with higher levels of hepatitis B-specific antibodies were less likely to develop diabetes compared to those with lower levels. Variations in antibody levels might correlate with the number of vaccinations received, timing of immunization, or individual immune responses.
No participants were purposefully infected with hepatitis B, suggesting that vaccination not only wards off the virus but may also lower diabetes risk, Fan notes. One explanation could be that vaccines help alleviate chronic inflammation damaging the liver and pancreas, which produce hormones like insulin regulate blood sugar levels.
Nonetheless, researchers cannot dismiss the theory that some protective benefits of vaccines might stem from their role in preventing infections, she adds. They are keen to investigate credible pathways and how mouse models can elucidate distinctions between diabetes types, Fan states.
Vaccinated individuals might also engage in healthier lifestyle choices, such as maintaining a nutritious diet and staying active. “Those likely to get vaccinated often exhibit greater awareness of health,” states Albert Osterhouse from the University of Veterinary Medicine in Hanover, Germany.
The research team considered factors including participants’ age, gender, and lifestyle choices like smoking, along with conditions such as obesity and hypertension. However, Osterhouse emphasizes the difficulty in ruling out the impact of these variables.
In a departure from conventional solid glass cores, the innovative optical fibers now incorporate an air core encased in precisely crafted glass microstructures to guide light. This advancement boosts transmission speeds by 45%, enabling greater data transfer over longer distances before amplification is required.
Petrovich et al. We report microstructured optical waveguides with unprecedented transmission bandwidth and attenuation. Image credit: Gemini AI.
Optical fibers in telecommunications have typically relied on solid silica glass constructs, and despite extensive refinements, their signal loss remains a critical challenge.
This results in about half of the light traveling through the fiber being lost after approximately 20 km, necessitating the use of optical amplifiers for extended distance communication, such as intercontinental terrestrial and undersea connections.
Minimizing signal loss can be achieved within a limited spectrum of wavelengths. This has constrained the data capacity in optical communications over recent decades.
Francesco Poletti and his team from the University of Southampton developed a new type of fiber optic featuring a hollow air core surrounded by intricately designed thin silica rings to effectively guide light.
Laboratory tests revealed that these fibers exhibit an optical loss of 0.091 decibels per kilometer at the commonly utilized optical wavelengths in communications.
Consequently, optical signals with appropriate wavelengths can travel approximately 50% farther before needing amplification.
This configuration offers a broader transmission window (the range of wavelengths where light propagates with minimal signal loss and distortion) than previous fiber optic technologies.
While this novel optical fiber may demonstrate lower losses due to the use of larger air cores, further investigation is necessary to validate these findings.
“We anticipate that advancements in manufacturing, geometric consistency, and reduced levels of absorbent gases in the core will solidify these new fibers as essential wave guiding technologies,” Reservers remarked.
“This breakthrough could pave the way for the next major advancement in data communication.”
Their study will be published in the journal Nature Photonics.
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M. Petrovich et al. Broadband optical fiber with attenuation of less than 0.1 decibels per kilometer. Nature Photonics Published online on September 1, 2025. doi:10.1038/s41566-025-01747-5
Researchers from CA ‘Foscari University have discovered Indigotin, a blue secondary compound also known as indigo, on a non-nanoparticle ground stone tool unearthed from the Zuziana Cave at the foot of the Caucasus in Georgia. Indigotin forms through reactions with atmospheric oxygen and natural glycoside precursors from leaves of the Isatis Tinctoria. This indicates that the plant was deliberately processed as far back as 34,000 years ago, despite its non-educational applications.
Five pebbles from Zugiana Cave, Georgia. Image credit: Longo et al., doi: 10.1371/journal.pone.0321262.
Modern humans first appeared in archaeological records approximately 300,000 years ago in Africa.
Much of the evidence regarding their cognitive and technical skills is derived from the limited existence of stone artifacts and the remains of animals, as these endure far longer in the archaeological record compared to plant materials.
As a result, Paleolithic narratives predominantly emphasize animal hunting and the production of stone tools.
The so-called “majority,” particularly plants that lack significant mentions, especially those increasingly shown to be utilized for food, cordage, weaving, and medicine, create incomplete accounts.
This underscores the need to identify and illustrate the roles of plants in an array of activities, many of which may still be undiscovered.
“It’s not solely about viewing plants as food resources; that’s common. We emphasize their involvement in complex processes. It possibly involves transforming perishable materials for use at various stages of Homo sapiens 34,000 years ago.”
“While the identification of elusive plant residues not typically highlighted in traditional research continually improves, our multi-analytical approach unveils fresh perspectives on the technical and cultural sophistication of Upper Paleolithic tools, designed to skillfully exploit the vast resources of plants and fully acknowledge their significance.”
In their investigation, researchers examined stone tools dating back 34,000 years, discovered in Zugiana Cave, Georgia.
They identified signs of mechanical processing of soft, wet materials consistent with plant matter such as leaves.
Employing an array of microscopic techniques (both optical and confocal), blue residues (occasionally fibrous) alongside starch grains were unexpectedly revealed.
These residues were particularly prevalent in the areas of the tools that displayed significant wear.
To ascertain the blue residues’ nature, scientists used advanced microscopy techniques, specifically Raman and FTIR spectroscopy.
These analyses confirmed the existence of indigotin chromophores in several samples.
“Once the molecules responsible for the blue coloration were identified, new questions arose. How and why were these residues associated with the tool’s working surface?” the author remarked.
They subsequently investigated the porosity of the stone, a crucial factor for trapping and retaining biological residues.
Both microscopic fragments of the archaeological tool and larger samples of experimental replicas underwent analysis using Micro-CT tomography.
This analysis confirmed the presence of pores capable of holding trace biological remnants.
Consequently, the team devised a series of replication experiments.
Initially, raw rock materials resembling those used by prehistoric inhabitants of Zuziana were sourced.
The pebbles were collected by Nino Jakeli from the Nikrisi River, located just beneath the cave.
Following this, controlled experiments were conducted, mechanically treating a range of plants, including fiber sources (such as bast fiber) and potentially indigotin-yielding species.
“We employed a rigorous approach to pollution control and biomolecular analysis to provide insights into contemporary human behaviors and the technical and ecological knowledge likely prioritized during the Upper Paleolithic era,” the researchers stated.
“Whether this plant remains serve medicinal purposes or have other uses presents a new perspective on the intriguing potential for diverse plant utilization.”
Survey results have been published online in the journal PLOS 1.
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L. Longo et al. 2025. Direct evidence of treatment of Isatis Tinctoria L., non-nutritional factories, 32-34,000 years ago. PLOS 1 20(5): E0321262; doi: 10.1371/journal.pone.0321262
Appendages of arthropods serve various functions, including feeding, locomotion, and reproduction. Fossils dating back to the Cambrian period (539-487 million years ago) provide remarkable details of extinct arthropod appendages, enhancing our understanding of their anatomy and ecological roles. However, due to the limited number of fossils and often incomplete preservation, studies on appendage functions typically depend on idealized reconstructions. This new research focuses on the paleontological species Olenoides serratus, a prolific trilobite from the Cambrian Burgess Shale, noteworthy for its numerous well-preserved specimens featuring soft tissue that allow for a detailed analysis of appendage functionality.
Olenoides serratus from Burgess Shale. Image credit: Losso et al., doi: 10.1186/s12915-025-02335-3.
Situated in British Columbia, Canada, the Burgess Shale is renowned for its exceptional fossil preservation, including soft tissues such as limbs and internal organs.
While trilobites are common in fossil records, their soft limbs are seldom preserved due to their hard exoskeleton, leading to a limited understanding of these structures.
The trilobite species Olenoides serratus offers a unique chance to investigate these appendages further.
Harvard paleontologist Sarah Ross and her team examined 156 limbs from 28 fossil specimens of Olenoides serratus to reconstruct the precise movements and functions of these ancient arthropod appendages, shedding light on one of the earliest successful aquatic animals.
“Understanding the behavior and movement of fossils poses challenges, as we cannot observe their activities like we do with living organisms,” stated Dr. Ross.
“Instead, we meticulously analyzed the morphology of numerous specimens while also utilizing modern analogues to infer how these ancient creatures lived.”
The researchers also assessed the range of motion of the legs of living horseshoe crab species Limulus polyphemus.
“Arthropods possess articulated legs composed of multiple segments that can flex upwards or downwards,” they noted.
“The range of motion is influenced by the specific directional capabilities of each joint.”
“This range, combined with the limbs’ shape and segment configuration, determines how the animal utilizes its appendages for walking, grasping, and burrowing.”
Horseshoe crabs, commonly found along the eastern coast of North America, are compared with trilobites due to their analogous behaviors.
“Despite their close relation to spiders and scorpions, horseshoe crabs are part of a different branch of the arthropod tree, whereas trilobite relationships remain ambiguous.”
The comparison arises from both animals’ adaptation of articulated limbs for navigating the seafloor.
However, the findings revealed that their similarities were minimal.
In contrast to horseshoe crabs, characterized by specialized limb joints for bending and expanding—facilitating feeding and protection—Olenoides serratus exhibited a simpler yet highly functional limb structure.
“We found that the limbs of Olenoides serratus had minimal extension, primarily far from the body,” Dr. Ross explained.
“Their limbs functioned differently than those of horseshoe crabs. Olenoides serratus could walk, dig, bring food to their mouths, and even elevate their bodies above the seafloor.”
To realize these findings, the scientists constructed advanced 3D digital models based on hundreds of fossil images captured from various angles.
Since trilobite limbs are often crushed and flattened, reconstructing them in three dimensions presents a significant challenge.
“We depend on exceptionally well-preserved specimens, comparing limb structures from multiple angles while leveraging related fossils to fill in any missing details,” said Professor Javier Ortega-Hernandez of Harvard University.
The team correlated the morphology of trace fossils to the movements of the limbs.
“The different movements of Olenoides serratus could create trace fossils with varying depths,” Dr. Ross elaborated.
“They were capable of raising their bodies on deposits, allowing them to traverse obstacles and navigate efficiently through swift currents.”
Remarkably, the researchers found that males possessed specialized appendages for mating, and each leg featured gills for respiration.
The findings were published in the journal BMC Biology on August 4th, 2025.
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Loss et al., 2025. Quantification of leg mobility in Burgess Shale Olenoides serratus reveals the functional differences between trilobite and Xiphosuran appendages. BMC Biol 23, 238; doi:10.1186/s12915-025-02335-3
Archaeologists from the Israeli Ancient Bureau (IAA) have discovered historical agricultural archaeological sites at the KH site, located in Kahru Chatta of central Israel.
Mosaic floors in the building of KH’s archaeological site. Israeli Kahufrata. Image credit: Israeli Ancient Bureau.
“The grandeur of the discovered structures, the exquisite quality of the mosaic floors, and the remarkable agricultural facilities indicate the significant wealth and prosperity of the local Samaritan community over time.”
“The Kh. KafrHatta site is noted as the birthplace of Menander, the Samaritan magician, a precursor to the Gnostics and a successor to Simon Magus, regarded as one of the first converts to Christianity.”
In one of the structures, archaeologists uncovered a stunning mosaic floor adorned with intricate geometric patterns and representations of plants.
“Alongside the central medallion, the acanthus leaves are interwoven with distinctive motifs of fruits and vegetables, including grapes, dates, watermelons, artichokes, and asparagus,” they noted.
“At the doorway of this room, a partially preserved Greek inscription wishes good fortune to the building’s owner!”
“The name of the owner was prevalent in the Samaritan community.”
In the northern area of the estate, researchers discovered olive presses, large storage buildings, and Mikube (public bathing facilities).
“The close proximity of the oil press to Mikube likely facilitated the production of high-quality olive oil,” they mentioned.
“The olive press was meticulously designed, comprising two wings.”
“The Northern Wing featured a major production area, while the Southern Wing included auxiliary facilities.”
“Within the production area, two screw presses and a large basin for crushed olives were found.”
“This type of olive press is more characteristic of the Jerusalem region and the Jewish Shephela, making it less common in Samaria,” explained Dr. Nagorsky.
“Over the years, the estate has experienced significant transformations.”
“The opulence and grandeur of the structures have been supplanted by oil production and agricultural infrastructure.”
“New walls damaged the mosaic floors, incorporating grand capitals and pillars into the updated structures.”
The team suggests these changes are connected to the Samaritan uprisings during Byzantine rule, which occurred in the 5th and 6th centuries, against Byzantine emperors who enforced restrictive laws on non-Christian communities.
“What makes this site particularly fascinating is that, unlike other Samaritan locations that were destroyed during these rebellions, the Kahru Kasim estate has continued to be used, preserving the Samaritan identity.
“It is a captivating site that illustrates the historical contrast between the era of prosperity and the decline of the Samaritan community,” remarked Dr. Nagorsky.
“Its longevity and remarkable findings enable us to reconstruct its history across centuries, enhancing our understanding of this ancient population.”
Illustration of rapamycin (red), a drug that inhibits proteins known as MTOR (blue)
Science Photo Library/Alamy
The anti-aging benefits of rapamycin may be related, at least in part, to its ability to prevent DNA damage in immune cells.
Initially created as an immunosuppressant for organ transplant patients, rapamycin blocks the function of the MTOR protein, which is crucial for cell growth and division. Studies suggest that low doses can extend the lifespan of various organisms, including the mouse, potentially by disrupting processes associated with aging, such as inflammation, intracellular breakdown, and decline in mitochondrial function.
Recent research by Lynn Cox and colleagues at Oxford University has demonstrated that rapamycin also appears to prevent DNA damage in certain types of immune cells. DNA damage is one of the key factors contributing to aging in our immune system, accelerating the aging process throughout the body.
The researchers conducted experiments with human T cells, a type of white blood cell responsible for fighting infections. When T cells were exposed to an antibiotic named zeocin alongside rapamycin, significant DNA damage occurred.
Results showed that rapamycin lowered DNA damage and tripled cell survival rates compared to T cells exposed to zeocin alone.
The researchers found no indication that the observed effects were due to other actions of rapamycin, such as preventing cell failure. “We consistently observe this effect regardless of whether rapamycin is administered prior to, during, or post-injury,” noted team member Ghada Arsare at Oxford University.
The rapid response suggests a direct impact. “The effect is very swift, indicating it influences the DNA damage response and accumulation. The lesions observed last about four hours, so it’s unlikely that there are downstream effects impacting other processes,” explained Cox.
According to Matt Kaeberlein from Washington University in Seattle, the findings support the notion that rapamycin can directly protect DNA, but “this is not the critical mechanism.” Researchers aim to explore rapamycin-induced alterations in RNA and proteins produced in immune cells.
In a separate part of the study, nine men aged 50 to 80 were assigned to receive either 1 milligram of rapamycin or a placebo daily. Blood tests conducted eight weeks later revealed that T cells from men taking rapamycin exhibited less DNA damage. Furthermore, neither group experienced a decrease in overall white blood cell counts, indicating that rapamycin does not negatively impact immune functionality. “Our findings confirm that low doses are safe, which is crucial,” stated Cox.
Mitigating DNA damage in the immune system may provide a pathway for reducing overall aging, according to Cox. Arsare highlighted the potential for rapamycin to be used preventively, such as for astronauts exposed to cosmic radiation.
“Rapamycin is particularly promising in addressing aging-related issues where DNA damage is a significant factor, such as skin aging,” noted Kaeberlein. Referring to a study, he added that local use of rapamycin reduces aging markers in human skin. However, he cautioned against generalizing results to other types of damage, such as radiation, given that Cox’s team used antibiotics to create DNA damage.
Zahida Sultanova from the University of East Anglia emphasized the necessity for trials involving women and individuals across various age groups, as the placebo-controlled experiments were limited to older men. Evidence from non-human animal studies indicates that rapamycin may have sex-specific and age-specific effects.
Nasal sprays available over-the-counter, historically noted for their safety and efficacy in treating seasonal allergies, could be perceived in a new light following clinical trial results released on Tuesday.
The antihistamine azelastine has been observed to have antiviral properties against various respiratory infections, including Influenza, RSV, and viruses responsible for COVID, according to a growing body of research.
Researchers from Saarland University Hospital in Germany conducted a study involving 450 adults, predominantly in their early 30s. One group of 227 participants used a nasal spray three times daily, while the other 223 received a placebo spray under the same regimen.
Throughout nearly two months, all participants underwent COVID rapid testing twice weekly. The results indicated that the incidence of symptomatic infections was 2.2% in the azelastine group, markedly lower than the 6.7% infection rate in the placebo group.
Furthermore, azelastine seemed to diminish the incidence of other symptomatic respiratory infections, as highlighted in a study published in JAMA Internal Medicine.
While researchers remain uncertain about the exact mechanism by which azelastine limits infections, they hypothesize that it may bind to the virus in the nasal mucosa.
Another possibility is that azelastine interacts with the ACE2 receptor, the primary entry point for COVID viruses into human cells, thereby preventing their attachment.
“Our findings imply that azelastine could serve as a scalable and commercially viable preventive measure against COVID, especially in high-risk scenarios such as crowded indoor events and travel,” the researchers noted.
However, the study had limitations, including that all participants were relatively young and healthy, according to the researchers.
Valz emphasized that azelastine should not replace vaccination and further research is essential before considering it as a standard precautionary measure for the public, particularly for vulnerable groups.
Dr. William Messer, associate professor at Oregon Health & Science University, found the results “rationally convincing” in terms of risk reduction, but pointed out the intensive regimen of daily sprays in the trial.
He questioned whether wearing a mask might be a simpler approach to preventing COVID infection.
“Masks can be inconvenient and bothersome, yet may be easier to adhere to than remembering to use three nasal sprays daily,” Messer remarked.
Nevertheless, he added, “I do not discourage anyone who wishes to try it.”
Other researchers are seeking more data to ascertain the effectiveness of nasal sprays in high-risk populations, such as the elderly and immunocompromised individuals who require additional preventive measures.
Dr. Peter Chin-Hong, a professor at UCSF Health specializing in Infectious Diseases, speculated that azelastine could serve as an additional COVID-blocking tool for individuals already using nasal sprays for seasonal allergies, although he believes the evidence is insufficient for broader recommendations.
“While the potential is promising, I believe now is not the appropriate time to recommend it as a COVID preventative,” he stated in an email. “For those over 65, I continue to advocate for vaccination as the primary defense against COVID.”
Nonetheless, Chin-Hong highlighted that the trial results underscore the importance of targeting the nasal mucosa in developing future vaccines against COVID and other respiratory viruses as a more effective means of infection prevention.
“Current COVID vaccines have not proven to be highly effective in preventing infection,” he remarked. “There is a need for more mucosal vaccines for respiratory viruses. While flu vaccines are widely used, ongoing efforts are being made to create mucosal vaccines for coronaviruses, necessitating continued advocacy for federal support and prioritization for these initiatives.”
Scrap vehicles are composed of various metal alloys, posing recycling challenges.
Mark Hill/Alamy
Innovative recycling methods for metals extracted from scrap cars can potentially eliminate millions of tons of waste annually while decreasing carbon emissions associated with the production of new aluminum.
Historically, a significant portion of scrap aluminum from cars has been repurposed into lower-grade cast alloys for engine blocks in traditional combustion engines. Yet, as the auto industry shifts towards electric vehicles, this low-grade metal no longer has utility.
Without effective strategies, there is a risk of generating millions of additional tons of carbon dioxide by accumulating “mountains” of unusable scrap and increasing the production of virgin aluminum for new vehicle manufacturing, warns Stephen Pogatcher from Leven University in Austria.
“As engine blocks become obsolete with electrification, we lack current paths for scrap utilization,” he cautions. “This constrains our recycling capabilities.”
Pogatscher and his team have developed a novel approach for recycling metals from scrap vehicles, which could convert approximately 7-9 million tons of waste annually into high-quality aluminum alloys suitable for various components of new cars.
The key lies in generating new products by harnessing a variety of alloy materials sourced from scrap vehicles, he elaborates.
Typically, when a car is discarded, its materials—plastic, fabric, steel, and aluminum—are processed separately. Moreover, as many as 40 different aluminum alloys are extracted from each vehicle across various recycling streams. Any non-separable components tend to blend into the engine block, associated with combustion engines.
The innovative recycling method pioneered by Pogatscher’s team involves melting all the scrap aluminum from the car simultaneously.
This results in a block of highly brittle material that resembles a metal ceramic, according to Pogatscher. Interestingly, the team found that reheating this block at approximately 500°C for 24 hours can restructure the metal, enhancing its strength and toughness. “Ultimately, it offers improved mechanical properties compared to conventional alloys,” he notes.
The team asserts that this new material rivals traditional automotive alloys, featuring “impressive” strength and versatility for fabricating various car components, including chassis and frames. Pogatscher emphasizes that it can be produced using standard industrial practices and has the potential for rapid scalability. While he recognizes the challenges in mainstream adoption of new alloys within the conservative manufacturing sector, discussions with industry partners regarding process development are already underway.
Jeffrey Scamans at Brunel University in London finds the concept “very intriguing,” but he stresses that further validation is essential, particularly to ensure the new alloy meets the stringent testing requirements for automotive applications.
He also cautions that achieving consistent high-quality alloys may be difficult since vehicles are discarded in a varied manner, not according to specific types. “It’s challenging to envision how to collect individual alloy compositions practically,” he remarks. “Scaling from laboratory experiments to full-scale metal production is notoriously complex.”
Mark Schlesinger at the Missouri University of Science and Technology states that commercial production must delineate and manage the composition of the new alloy. “Randomly mixing scrap in the furnace won’t yield acceptable results,” he says. “This necessitates precise scrap chemistry assessments, which subsequently raises handling costs.”
If you’ve recently browsed fitness content on platforms like Instagram, Facebook, or TikTok, you might have encountered influencers who have used steroids. A recent global meta-analysis suggests that steroid usage among gym-goers varies from 6% to a shocking 29% across different countries.
This statistic might come as a shock. According to Timothy Piatkovski from Griffith University, the landscape of steroid use has evolved over the last decade. Many fitness influencers now present themselves as knowledgeable figures, openly discussing their drug use and advising followers on steroid usage.
“Regrettably, the level of medical knowledge and judgment varies significantly among these influencers,” states Piatkowski.
Influencers’ perceptions of health risks differ greatly, he observes. While some acknowledge the dangers of steroid use, asserting that risks can be managed sensibly, others are more reckless, promoting drugs like trenbolone, which is typically used to prevent muscle wastage in livestock, branding themselves as “Trenfluencers.”
Millions may question whether these substances are actually safe, or if influencers are leading them into perilous situations. What is the truth regarding the dangers associated with steroids? Is there a safer way to use them?
Piatkowski notes that research on the long-term health consequences of steroids is sparse. This is largely due to the mismatch between doses and usage patterns studied by researchers and those employed by actual users. He and his colleagues seek to bridge this gap by collaborating closely with steroid users to create more relevant and realistic studies.
However, this mismatch has already led to some influencers losing faith in mainstream scientific and medical perspectives, prompting users to seek advice from fitness and bodybuilding forums instead. These social media channels have become a major contributor to both the support network and the marketplace in the surge of steroid usage.
Users now have quick access to a range of substances that can be obtained illicitly. This includes oral anabolic steroids known as SARMs (selective androgen receptor modulators) and synthetic human growth hormone, naturally produced by the pituitary gland during adolescence. Collectively, they improve physique and performance, but their mechanisms can vary significantly.
One of the most prevalent substances is anabolic steroids, potent synthetic derivatives of testosterone. A 2022 study estimated that around half a million men and boys in the UK used them for non-medical purposes in the previous year.
Understanding Steroids
To determine whether steroids are safe, one must first grasp their effects on the body. Anabolic androgen steroids work by interacting with hormonal receptors that promote male sexual traits, particularly in muscle and bone tissues. “They aid in muscle growth and are vital for bone development; they guide boys through puberty and literally transform them into men,” explains Channa Jayasena from Imperial College London.
The desired result is evident: a bigger, stronger physique in a shorter timeframe. Medically, some of these substances are prescribed to treat conditions like muscle wasting associated with HIV. At lower doses, investigations suggest that steroids can be well tolerated. However, this is not a strategy commonly employed outside clinical settings.
Non-medical steroid use rarely mimics regulated clinical trials. Many users resort to “stacking” various drugs and alternate between cycles to allow bodily recovery, adopting practices like the “blast and cruise” regimen. Although these methods lack comprehensive scientific scrutiny, influencers often tout them as ways to minimize health risks or achieve effective muscle growth. This could explain why many users turn to influencers and online forums instead of healthcare professionals for advice.
The Risks of Unregulated Use
The temptation to test various drug combinations or follow cycling protocols stems from the belief that such strategies mitigate the adverse effects of anabolic steroids. The best-documented side effect is cardiovascular complications. Anabolic steroids are known to lower levels of high-density lipoproteins, or “good” cholesterol, while raising blood pressure and increasing low-density lipoproteins, known as “bad” cholesterol. This can thicken the heart muscle, potentially leading to cardiomyopathy—severe heart dysfunction and a lethal condition, as noted by Jayasena.
A Danish population study revealed that anabolic steroid users were three times more likely to die than other males during the study’s duration. “It’s akin to cocaine,” asserts Jayasena. Cardiovascular disease and cancer emerged as the most prevalent natural causes of death among these individuals.
Increased risk of heart disease and stroke is a well-known consequence of prolonged anabolic steroid use
3dmedisphere/shutterstock
Beyond cardiovascular matters, Jayasena highlights that the psychosocial implications of steroid use are significant and well-documented. The term “Roid Rage” encompasses various mental issues including aggression, mania, and mental illness—particularly among individuals consuming high doses. “When observing why steroid users have fatal outcomes, one notes three primary causes: cardiomyopathy, suicide, and aggression,” he notes, suggesting a possible correlation between steroid use and heightened tendencies toward criminal behavior.
This relationship remains contentious, as it’s challenging to differentiate the effects of steroid use from other contributing factors like recreational drug usage or pre-existing mental health issues. Nonetheless, it indicates that discontinuing steroid use may precipitate depression and suicidal thoughts. “The mind becomes lethargic,” explains Jayasena. “The recovery period can extend over months, sometimes even years.”
Research led by Jayasena revealed that nearly 30% of men who ceased steroid use experienced suicidal thoughts and major depression, possibly due to lingering steroid residues in brain areas responsible for emotional regulation. Additional studies indicate that steroids can impair kidney function and elevate cancer risks, although the data is less conclusive and heavily reliant on isolated medical case reports.
Several investigations have demonstrated that some of these health concerns might be reversible. For instance, the liver appears adept at self-repair and can manage lower clinical doses of certain steroids. Conversely, effects like high cholesterol and hypertension can be reversible post-steroid cessation; in contrast, others may require long-term or costly interventions to address, such as mood disorders and infertility.
The most severe repercussions of steroid use tend to be the hardest to treat. Structural alterations in the heart, along with research indicating lasting blood flow impairments to vital organs, is a concern that may linger long after users cease taking steroids.
Seeking “Safer” Steroids
Given the extensive and complex list of potential harms, many users experiment with steroid protocols aimed at risk reduction. This includes altering doses, timing, or combining them with other substances. However, there is a dearth of research examining the safety of these “protocols,” asserts Piatkowski.
One of Jayasena’s studies indicated that post-cycle therapy, where users take medications to restore natural testosterone production following steroid cycles, significantly lowered the risk of suicidal thoughts. Piatkowski’s research compares high-dose cycles and gradual tapering, identifying that those following a Blast Cruise approach reported fewer adverse health effects once they stopped using.
High-quality, controlled studies evaluating the effects of recreational steroid use are sparse, often characterized by small sample sizes or case reports that complicate the establishment of causal relationships. The evidence supporting specific protocols is also thin, particularly as patterns of steroid use evolve more rapidly than researchers can track.
Anabolic steroids are commonly injected into the subcutaneous fat layer located between the skin and muscle.
ole_cnx/istockphoto/getty images
“Further longitudinal and cohort studies are essential,” Piatkowski asserts. Such studies track individuals’ health and wellbeing over time, ultimately clarifying real risks and potentially providing strategies for risk mitigation. Nevertheless, in the absence of robust evidence, healthcare providers often struggle to offer guidance to steroid users.
Greg James, a clinician at Kratos Medical in Cardiff, UK, mentions that he provides private health and blood testing services. Some patients even inquire about combining steroids with GLP-1 drugs that suppress appetite, as well as other peptides that regulate hunger. “They ask me if these peptides are safe,” James notes. “And I respond that I cannot confirm their safety due to the lack of long-term data.”
Researchers like Piatkowski are beginning to directly engage with users in realistic settings, navigating the challenges posed by inadequate clinical data and rapidly changing user behaviors. Rather than viewing users as patients or outliers, this method considers them as valuable sources of real-life experience, contributing to the development of more relevant and realistic research.
A recent study conducted by Piatkowski and collaborators examined steroid samples from users, revealing that over 20% were contaminated with toxic substances such as lead, arsenic, and mercury. More than half were incorrectly administered, meaning users may have been taking far more potent agents intended for livestock use.
Another study involving interviews with diverse steroid users identified trenbolone as having the most negative consequences, particularly for psychological and social health. This suggests that focusing on trenbolone as a distinct harmful substance, along with targeted screening and intervention strategies, could be more effective for harm reduction compared to broad-ranging methods.
Fitness influencers are frequently regarded as authorities who provide guidance on anabolic steroid use to their followers.
Kritchanut Onmang/Alamy
This open and collaborative methodology in drug research mirrors approaches seen in other recreational drug strategies, like psychedelic research. By engaging with real users, insight can be gained not only into harm reduction techniques but also previously unrecognized medicinal applications.
They may also collaborate with influencers and users to promote safer behaviors, rather than outright condemning drug usage, Piatkowski emphasizes. “Enhancing knowledge within these communities and legalizing information is crucial. It’s an ongoing experimental endeavor. The more we stimulate this discussion, the more we can advance the field.”
In 1964, a San Diego high school student named Randy Gardner participated in a Science Fair Project by staying awake for an astounding 11 days.
By the second day of the experiment, Gardner began to experience memory lapses. By the seventh day, he suffered from intense hallucinations, and by the 11th day, he exhibited inconsistencies, paranoia, and muscular tremors.
Fortunately, the 17-year-old fully recovered without any lasting effects. No one has surpassed this record since then, as noted in the Guinness Record Book. Due to health concerns, sleep deprivation records were discontinued in 1997.
However, cognitive decline can occur without an 11-day deprivation; even a few nights of poor sleep can lead to diminished functioning, memory recall, and emotional regulation.
Now, let’s explore the science behind sleep and its impact on brain performance.
What happens to your brain while you’re sleeping?
Photo credit: Getty
During sleep, our brains engage in essential repairs and various tasks, including removing waste and detoxifying itself.
Short-term memories are organized, long-term memories in the neocortex are solidified, and REM sleep plays a crucial role in problem-solving and emotional regulation.
But it’s not just all activity; there are restorative phases during non-REM sleep stages 1, 2, and 3, which slow the heartbeat, relax the muscles, and reduce brain wave activity—with brief bursts during stage 2.
In REM sleep, brain activity intensifies, resembling the state of wakefulness. The amygdala and hippocampus are highly active, aiding in memory processing and emotion regulation. This dream phase supports creative thinking when you wake up.
Brain impacts of poor sleep
Lack of sleep or poor sleep quality can impact your brain’s performance in several ways.
The prefrontal cortex, responsible for decision-making and problem-solving, becomes less effective. This leads to reduced attention, cognitive flexibility, and working memory.
An overactive amygdala can hinder the emotional contextualization of information, and difficulties in storing information in the cortex weaken memory integration.
Other short-term effects of inadequate sleep include: • Impaired judgment • Slowed reaction times • Declined risk assessment
When sleep deprivation becomes normal
For individuals with chronic sleep disorders, these short-term consequences are part of their everyday reality.
Moreover, chronic sleep deprivation has serious ramifications. Research conducted by the National Medical Library reveals a link between chronic sleep deprivation and Alzheimer’s disease.
“Studies indicate that sleep performs essential housekeeping, such as clearing potentially harmful beta-amyloid proteins,” states the Sleep Foundation.
“In Alzheimer’s disease, the aggregation of beta-amyloid leads to cognitive decline. Even one night of sleep deprivation can increase the accumulation of beta-amyloid in the brain.”
According to one study, individuals with sleep disorders have a significantly elevated risk of developing Alzheimer’s, with an estimated 15% of cases linked to lack of sleep.
Maintaining brain health and cognitive function heavily relies on regular, quality sleep, making it essential to optimize your sleep environment.
Optimizing sleep quality
Hästens, a bed maker based in Sweden, recognizes the vital importance of quality sleep. Since 1852, Hästens has crafted handmade beds in the Swedish town of Kaepi, taking up to 600 hours and using only natural materials.
“A good night’s sleep will enhance your performance,” notes Hästens. “In today’s fast-paced world, sleep may feel like a luxury, but from a medical standpoint, it’s crucial for a strong immune system and overall health.”
Explore the full range of Hästens beds and accessories, and learn more about the benefits of quality sleep here.
Local Hästens Sleep Spa bed tests can be booked online www.hastens.com or at your nearest certified retailer.
When you mention buying a used car to most people, they tend to shy away. Some roll their eyes, claiming they want to avoid risks.
However, there are others who argue that it was the best decision they ever made. I count myself among them.
Having driven electric vehicles (EVs) daily for 15 years, owning seven different models, and covering 170,000 miles with just one set of batteries, I’ve gained valuable insights. Remarkably, I’ve faced no issues during those miles.
My only repair bill came recently. For my Tesla Model 3, the cost to replace the front control arm bushes was £375. I’ve owned it for five years and clocked 50,000 miles.
Driving Made Easier
Purchasing a used EV carries far less risk compared to a pre-owned combustion engine vehicle. An EV drivetrain consists of roughly 20 moving parts, unlike the endless list of potential issues in gasoline or diesel vehicles—think clutches, gearboxes, fuel pumps, and exhaust systems.
Numerous studies confirm that EVs degrade less quickly than their combustion counterparts.
For routine maintenance on your EV, you’ll primarily need to replace the cabin filter, change the brake fluid every three years, and rotate the tires. This is due to the limited number of friction-based components.
Understanding the mechanical simplicity of EVs helps identify key maintenance areas to watch for.
The most significant concern for used EV buyers is the battery. Luckily, extensive data shows that lithium-ion batteries have low failure rates.
Most EVs come with an 8-year, 100,000-mile battery warranty. If the capacity dips below 70%, the manufacturer will replace it at no cost. I drove one EV 250,000 miles with its original battery pack before it exited warranty.
Some EVs even show original battery packs functioning well beyond 300,000 miles.
Today, experts agree that EV batteries may even outlast the car chassis.
According to Consumer Reports, average battery packs have a lifespan of approximately 200,000 miles, while Geotab Research showed only a 10% loss in capacity among 10,000 EVs over ten years.
In contrast, combustion engines tend to lose efficiency due to wear and tear after just ten years.
read more:
What to Look For
Dealers now offer State of Health (SOH) certificates for batteries, and many EVs come with software allowing owners to check the SOH themselves. For instance, I checked my Tesla at 50,000 miles and found it still had 93% capacity.
When buying from a dealer, request a SOH certificate, or verify battery capacity in private sales. A capacity around 90% suggests minimal cell degradation, indicating plenty of useful life left.
However, some models have had issues. Early Nissan Leafs had battery cooling problems, resulting in a faster loss of range and capacity than other EVs.
Initial Renault Zoes faced battery management issues, while older electric smart vehicles can be challenging to maintain. Similarly, the earliest BMW i3 models showed reliability glitches, as noted by What Car. The concerns also extend to the MG4 and Vauxhall Corsa E.
The consensus is to be cautious with earlier EV models.
Though there’s no official count of private charging points in the UK, the charging point mapping app ZAPMAP estimates over 1 million locations. Photo credit: Alamy
Battery technology has evolved, providing better software, extended ranges, and faster charging times.
Some EVs feature Chademo plugs, which are being phased out in many regions. Adapters are available to convert these to the universally used CCS charging system.
Choosing EVs from 2017 onward generally means accessing more advanced technology.
Hybrid batteries tend to wear out faster due to frequent charging cycles, leading to premature failures.
Hybrids are also less reliable compared to purely electric EVs. This is compounded by the dual powertrains of gasoline engines and batteries.
Additionally, maintaining hybrids can be costlier. Their electric ranges typically fall between 20-40 miles for plug-in hybrids, while mild and full hybrids rely primarily on gasoline engines and aren’t true EVs.
Some EVs have encountered problems with charging port flaps, ports, and cables, although these issues are relatively rare.
Make sure to test the charging port and flap functionality prior to finalizing a purchase. Monitor the central screen for charging alerts and connection failures.
Before you arrive, ensure the seller has charged the battery to 100% and check the displayed range against the manufacturer’s estimate. If it’s significantly lower, reconsider the purchase.
While most EVs experience range reductions in cold weather, a warm ambient temperature should yield a range close to official numbers. EVs equipped with heat pumps show improved low-temperature performance.
Although 12-volt batteries in some EVs (similar to combustion vehicles) may lose charge over time, it’s advisable to replace the auxiliary battery every three years. This can impact how effectively the main battery charges, potentially triggering software issues.
Beyond electrical concerns, inspect for suspension wear in the front control arms and bushes. If you notice any rattling or creaking, inquire about it; the EV should operate smoothly and quietly.
Currently, a robust global dataset confirms that EVs are generally more reliable than gasoline or diesel vehicles.
Lastly, before buying, consider investing in a home charging unit (if space permits) to facilitate convenient charging at home.
This allows for an average full charge cost of under £15, translating to about 3p per mile. Even with a second-hand EV, this is significantly more economical than traditional filling stations for petrol and diesel vehicles.
Using the Widefield Camera 3 (WFC3) mounted on the NASA/ESA Hubble Space Telescope, astronomers have captured a breathtaking new image of the Spiral Galaxy NGC 7456.
This Hubble image showcases NGC 7456, a spiral galaxy located 51 million light-years away in the constellation of Grus. Image credits: NASA/ESA/Hubble/D. Thilker.
NGC 7456 was discovered by British astronomer John Herschel on September 4, 1834.
This galaxy is approximately 51 million light-years from Earth, in the constellation Grus.
Also referred to as ESO 346-26, IRAS 22594-3950, or LEDA 70304, it spans a diameter of 117,100 light-years.
The NGC 7456 belongs to the LDC 1547 Galaxy Group, which includes 16 large galaxies.
“In Hubble’s image, one can observe the intricate, swirling arms of this galaxy in exquisite detail, complemented by a dark, diffuse mass of dust,” remarked an astronomer from Webb.
“The bright pink regions signify gas-rich areas where new stars are emerging, illuminating the surrounding clouds, as this gas emits transmitted red light.”
“The Hubble program has been gathering these data to study stellar activity, tracking new star-forming clouds, hydrogen, star clusters, and gaining insights into galaxy evolution over time,” they further explained.
“With its capability to capture visible ultraviolet and some infrared light, Hubble isn’t the only observatory focused on NGC 7456.”
“ESA’s XMM-Newton satellite has imaged X-rays from galaxies multiple times and discovered what is known as a hyper-luminous X-ray source.”
“These compact objects emit significantly more powerful X-rays than one would expect for their size.”
“We are still investigating what drives these extreme objects. NGC 7456 contributes several examples to this research.”
“Additionally, the area surrounding the galaxy’s supermassive black hole is incredibly bright and energetic, making NGC 7456 an active galaxy.”
“Whether viewed in visible light or X-rays, there’s always something intriguing about this galaxy, whether focusing on its core or its outer regions.”
Based on data gathered by the sensors aboard the US Department of Defense Space Test Program Satellite 6 (STP-SAT6), we discovered a direct correlation between the frequency of electrical discharges on a spacecraft and the electron density in its environment.
STP-SAT6. Image credit: Northrop Grumman.
Spacecraft environmental discharges (SEDs) are short-lived electrical failures that may harm sensitive onboard electronics and communication systems.
While researchers have acknowledged the presence of SEDs for some time, the relationship between spatial environments and their electrons remains unclear.
“To explore this, we required two sensors on the same spacecraft: one to monitor electron quantity and activity, and another to detect radio frequency signals,” explained Dr. Amitabh Nag, a researcher at Los Alamos National Laboratory.
SEDs arise from variations in surface charging, typically due to the accumulation of electrons on the surfaces of orbiting spacecraft.
This process differs from static electricity on Earth. For instance, when someone walks across a carpet and discharges static after touching a door handle, a buildup of energy occurs. Likewise, when a spacecraft’s energy storage reaches a critical voltage, it results in an electrical discharge in space.
The STP-SAT6 is fitted with both sensors, allowing a unique opportunity for researchers to analyze both radio frequency and electronic activity simultaneously.
“We managed to assess the speed of SEDs as reported by the radio frequency sensors and compare it with the electronic particle activity within specific voltage ranges,” Dr. Nag noted.
“Our findings indicated that the peak of SEDs coincides with the peak of electronic activity.”
The authors analyzed data from two sensors over a year-long period, identifying heightened electronic activity during 270 high-speed SED occurrences and numerous episodes.
In roughly three-quarters of instances, the peak in electronic activity occurred 24-45 minutes before the SED event.
This delay implies that the buildup of charge from low-energy electrons plays a crucial role in preparing the spacecraft for electrostatic discharge.
“We noted that as electronic activity increases, the spacecraft begins to gather charges, especially in the 7.9-12.2 keV range,” Dr. Nag added.
“This process continues until a tipping point is reached, resulting in an SED.”
“Such lead time presents an opportunity for potential forecasting tools to reduce risks.”
“Future missions could include real-time monitoring of low-energy electrons to predict and react to charging events before they disrupt operations.”
The results will be published in the journal Advances in Space Research.
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Amitabag et al. 2025. Radio frequency transients correlated with electronic flux installed in STP-SAT6. Advances in Space Research 76 (6): 3692-3699; doi: 10.1016/j.asr.2025.07.026
Named Huashanosaurus Qini, this new dinosaur species is estimated to be about 12 m (39 feet) in length.
It existed in the Cantonese Autonomous Region of present-day China approximately 200 to 162 million years ago.
“The Jurassic sauropods are notably abundant in China, particularly in regions like Yunnan, Sichuan, and Xinjiang, with fewer known areas such as Ganshu, Ningxia, Anhui, Tibet, and Gitsou.”
“In Guangzhou, the record of Jurassic dinosaur fossils is limited compared to those from the Cretaceous period.”
Two specimens of Huashanosaurus Qini, including partial skeletons, were collected from Huqiu Quarry, part of The King’s Formation, located east of Guangzhou in southern China.
The site also yielded some bone fish scales, teeth (likely from Scalpidotes sp.), incomplete plesiosaur teeth, and fragmentary dinosaur bones.
“There is an ongoing debate regarding the geological age of the Prince Formation,” remarked the paleontologists.
“Initially thought to be early Jurassic, the formation has limited paleontological evidence.”
“Scientists are considering it to date from early to mid-Jurassic due to the presence of larger species from this era.”
The team indicates that Huashanosaurus Qini is a member of eusauropoda, a derived group of sauropod dinosaurs.
“This marks Guangzhou’s second eusauropod discovery,” the researcher noted.
“The first eusauropod described, Jingia dongxingensis, was excavated from the late Jurassic Dung Xing Formation.”
The discovery of Huashanosaurus Qini adds valuable information to the understanding of the evolutionary diversification of eusauropod dinosaurs.
“Huashanosaurus Qini is positioned more basally than early Jurassic forms like Balcanodon, Tazoudasaurus, and Goncyanosaurus, as well as early to mid-Jurassic representatives such as Barapasaurus,” stated the scientist.
“It is generally accepted that the main radiation of eusauropods occurred towards the end of the early Jurassic and the early Jurassic intervals.”
“From this perspective, the discovery of Huashanosaurus Qini provides further evidence for early to mid-King’s age.”
Survey results have been published in the journal Acta Geologica Sinica.
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Jinyou Mo et al. 2025. A new eusauropod dinosaur from the Jurassic Prince Formation in lower and central Nieming County in Guangzhou, southern China. Acta Geologica Sinica 99(4): 909-924; doi: 10.1111/1755-6724.15331
Consider the idea of sustainable cuisine. While humble lentils may come to mind, is it feasible to indulge in luxurious options while remaining eco-conscious? Bivalves like oysters, mussels, scallops, and clams possess inherent green credentials thanks to their ability to purify polluted waters. Recent research indicates they might also help sequester carbon. Could agricultural bivalves emerge as the pinnacle of sustainable food?
Food production contributes to around a third of global greenhouse gas emissions, making it crucial to identify options that mitigate this damage. In seafood, aquaculture is generally more sustainable than wild fishing; however, farmed fish rely on wild fish for part of their diet. Recent studies reveal that the reliance on wild fish for aquaculture feed is often underestimated. Additionally, fish farms can create significant waste issues from fish excrement and uneaten feed.
A notable advantage of bivalves is their minimal need for supplemental feed. As filter feeders, they consume tiny nutrient particles suspended in seawater and plankton. With most coastal waters currently suffering from nutrient overload due to nitrogen and phosphorus runoff, harvesting cultivated bivalves can help alleviate this excess and purify the waters as a byproduct of their production.
Conversely, harvesting wild bivalves poses ecological threats. For instance, overfishing of wild scallops can damage delicate marine ecosystems like seafans, corals, and sponges. However, comparison shows that farmed bivalves come with significantly fewer drawbacks, especially when compared to rainforest destruction for beef production.
But there’s more to explore. In recent years, various studies have suggested that agricultural bivalves can sequester carbon, potentially allowing farms to earn carbon credits as an additional revenue stream.
Yet, Fabrice Pernett from Brest University in France remains skeptical. A review of over 50 studies has left him unconvinced. Many of these studies are based on theoretical models that assume the formation of calcium carbonate shells absorbs CO.2 from the sea.
However, this phenomenon holds true only over geological timescales. Over shorter periods—critical when addressing climate change—the carbon cycle shows carbonate formation often releases CO.2.
Moreover, the common practice of incinerating waste shells frequently leads to even more CO.2 being released into the atmosphere instead of returning carbon to the ocean to mitigate CO.2 emissions. Similarly, carbon from the flesh of seafood also gets released as CO.2 following consumption.
Some researchers are now claiming that organic matter deposited under bivalves represents a significant carbon sink.
This latest assertion builds upon oyster research conducted within five large enclosures. However, Pernett cautions that similar studies feature shortcomings, such as CO.2 measurements being conducted only during the day and summer months when photosynthesis peaks.
The research team argues this limitation does not influence the findings. “The budget suggests that carbon accumulation and sequestration exceed carbon extracted in shells,” asserts Shuang-lin Dong from China Maritime University. Nevertheless, Pernett is still unconvinced. “Current evidence indicates that bivalve farming releases CO.2 overall,” he remarks.
However, don’t cancel your reservation at your favorite oyster bar just yet. Although bivalve farming may be a carbon emitter, the emissions are relatively low—around 1.4 kilograms of CO.2 per kilogram of edible weight based on 2021 research. This figures significantly lower than that of wheat or corn, all while requiring less land and freshwater.
“Indeed, agricultural bivalves rank among the greenest food sources,” states Pernett. A culinary delight.
Exercise doesn’t need to be lengthy to yield substantial rewards
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If you’re skipping exercise due to time constraints, integrating just a few short bursts of activity—like 5 to 6 active sessions of 10 seconds each—can greatly impact your health. A US study revealed that individuals engaging in over a minute of intense activity daily had a significantly lower mortality risk over the next six years compared to those who were inactive.
Currently, only about 15% of adults participate in regular exercise, according to Emmanuel Stamatakis from the University of Sydney, Australia. “The majority of the adult population struggles with including regular exercise into their routine, whether due to a lack of interest or difficulty.”
To further investigate, Stamatakis and his team studied the health benefits associated with incidental exercise, which can occur through activities like walking downhill, playfully engaging with children, and carrying heavy objects. They monitored participants for one week as part of a larger health study, assessing their activity levels and examining mortality risks in the following year.
In 2023, findings from the UK Biobank study involving tens of thousands of participants indicated that those with approximately 4.4 minutes of daily active time were 38% less likely to die from any cause in the next seven to eight years compared to non-exercisers.
Additionally, the research included results from 3,300 individuals in the US NHANES study. “This group, on average, is significantly overweight and less active,” remarks Stamatakis.
This group only required 1.1 minutes of intense activity daily to lower their overall mortality risk by 38% over the subsequent six years.
This demonstrates that this less active US group experienced similar relative benefits with just 1.1 and 4.4 minutes of activity found in the fitter UK group; however, it doesn’t imply they reached the same health status. Participants in the US study generally had lower fitness levels to start with and were at a higher baseline risk of mortality.
“This observation may indicate a more sedentary, higher-risk demographic that benefits considerably from minor increases in activity, and I concur,” states Carlos Celis Morales from the University of Glasgow, UK. “This phenomenon is known as the ceiling effect; those with high fitness levels have diminished potential for further improvement, while individuals with lower fitness levels have significant room for enhancement.”
The findings further support the notion that even small amounts of intense, unintentional movement can yield substantial health benefits. However, Stamatakis cautions that causation hasn’t been firmly established yet. “While it seems logical that health benefits might exist,” he notes. “This type of study cannot definitively prove causality.”
His research team is planning future studies to provide stronger evidence that observed health improvements stem from increased incidental exercise. “Our long-term objective is to discover methods to incorporate more activity into people’s everyday lives without requiring trips to the gym,” Stamatakis expresses.
Sheet Web Spider Psechrus Clavis is known to utilize the coloration and web of its own body as visual cues to effectively capture and consume insects. Interestingly, it doesn’t immediately eat the male fireflies, referred to as Daifan Lampaloid; instead, these spiders retain them on the web, allowing the fireflies to continue emitting bioluminescent signals for up to an hour. This observation has raised intriguing questions among a research team from Tunghai University, the University of New South Wales, the Sydney Institute of Technology, and the National Museum of Natural Sciences in Taiwan.
Sheet web spider with fireflies caught in the web. Image credit: Tunghai University Spider.
Researcher I-Min TSO and colleagues at Tunghai University documented Psechrus Clavis retaining fireflies on the web while these insects continued to emit bioluminescent light for up to an hour.
They noted that the spiders periodically check for the captured fireflies.
Fascinated by this peculiar behavior, the researchers designed an experiment to see if it serves as a hunting strategy.
The experiment involved placing firefly-like LEDs on the actual sheet spider web, using other webs as controls.
The results indicated that the web with LEDs attracted three times as many prey compared to the control web.
This figure increased to ten times more prey when actual fireflies were visible.
The findings affirm that the presence of captured fireflies enhances the spider’s hunting success.
Researchers also discovered that the majority of captured fireflies are male and likely mistaken for potential mates.
“Our findings underscore the previously unrecognized interaction where Firefly Signals, intended for sexual communication, also benefit spiders,” remarked Dr. TSO.
“This study provides new insights into how sit-and-wait predators can adapt to attract prey, revealing the intricate complexities of predator-prey interactions.”
“This behavior may have evolved in sheet web spiders as a way to avoid the energy costs associated with producing their own bioluminescence, similar to anglerfish.”
“Instead, spiders can leverage the allure of their prey’s glow to attract their own targets.”
Video recordings taken during the experiments show sheet web spiders employing various tactics when interacting with different prey species.
The spider swiftly consumes a moth caught in the web but takes its time with the trapped fireflies.
“The varying treatment of prey suggests that spiders may use specific cues to differentiate between prey species and adjust their responses accordingly,” explained Dr. TSO.
“We hypothesize that the bioluminescent signals of fireflies help spiders to fine-tune their handling behavior towards different types of prey.”
This study was published in Journal of Animal Ecology.
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Ho Yin Yip et al. Visual seduction through bioluminescence of prey seduces waiting predators. Journal of Animal Ecology Published online on August 27th, 2025. doi:10.1111/1365-2656.70102
A recent study discovered that engaging in high-ventilation breathing exercises while listening to music is linked to experiencing blissful states and diminishing negative emotions. This practice is also associated with increased blood flow to brain areas responsible for processing emotions.
Kartar et al. We propose that circuits supporting the integration of mutual acceptoral expressions and the processing of emotional memory are potential neurobiological substrates for HVB-induced ASCs. Image credit: Ram Jain.
The use of breathing exercises as a method for alleviating psychological distress is rapidly gaining traction. Breathing techniques that enhance ventilation rate or depth in conjunction with music can lead to altered states of consciousness (ASC) akin to those induced by psychedelic substances.
High ventilation breathing (HVB) may present fewer legal and ethical challenges for widespread use in clinical settings, offering a non-pharmaceutical alternative.
Nevertheless, the neurobiological mechanisms and subjective experiences linked to ASCs resulting from HVB have not been thoroughly explored.
To address this knowledge deficiency, Dr. Amy Amra Kartal from the University of Sussex and her team characterized ASCs triggered by HVB conducted by experienced practitioners, analyzing self-reported data from 15 participants online, and 8 to 19 individuals in a lab setting.
Their study included 20-30 minute sessions of uninterrupted circular breathing paired with music, followed by various surveys within 30 minutes post-session.
Findings indicated that the intensity of ASCs from HVB correlates with cardiovascular sympathetic activation and shows signs of a potential stress response, evidenced by decreased heart rate variability.
Moreover, HVB-induced ASCs were related to a significant reduction in blood flow to specific brain areas, including the left surgery and posterior island, which are involved in representing the body’s internal state, including respiration.
Interestingly, despite an overall reduction in cerebral blood flow during HVB, there were increases noted in the right amygdala and anterior hippocampus—regions pertinent to emotional memory processing.
These alterations in blood flow bear a resemblance to psychedelic experiences, suggesting that such changes may underlie the beneficial effects of this breathing technique.
Throughout all experimental conditions, participants reported a decrease in fear and negative emotions without experiencing side effects.
In various participant settings, HVB indeed reinforced the marine infinity (OBN)-controlled ASC, a concept introduced by Freud in 1920, encapsulating a range of experiences such as spiritual insights, feelings of bliss, positive emotional shifts, and a sense of unity.
OBN is regarded as a fundamental element of ASCs generated by psychedelic substances like psilocybin.
The researchers emphasize that their findings are pioneering and exploratory, advocating for future studies with larger sample sizes and control groups to discern the effects of music on brain activity.
Despite certain limitations, these results offer valuable insights into HVB and its potential therapeutic applications.
“Our research represents the first use of neuroimaging to map the neurophysiological changes occurring during respiratory work,” the team stated.
“Key findings indicate that breathing exercises elicit profound psychedelic states.”
“We believe these conditions are tied to shifts in function in specific brain areas involved in self-awareness, fear, and emotional memory processing.”
“We discovered that deeper alterations in blood flow in certain brain regions correspond to stronger sensations of unity, bliss, and emotional release referred to as ‘marine boundaries.’ ”
Survey results published online in the journal on August 27, 2025 PLOS 1.
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Kartar et al. 2025. Neurobiological substrates of altered states of consciousness induced by high ventilator respiratory practices with music. PLOS 1 20(8): E0329411; doi: 10.1371/journal.pone.0329411
Cancer arises from the proliferation of abnormal, uncontrolled cells that create dense masses, known as Solid Tumors. These cancer cells possess unique surface markers called antigens that can be identified by immune cells. A crucial component of our immune system, T cells, carry a protective protein known as FASL, which aids in destroying cancer cells. When T cells encounter cancer antigens, they become activated and initiate an attack on the tumor.
One form of immunotherapy, referred to as chimeric antigen receptor T cell therapy or CAR-T therapy, involves reprogramming a patient’s T cells to recognize cancer cell antigens. However, CAR-T therapy often struggles with solid tumors due to the dense, hostile environment within these tumors, which obstructs immune cells from infiltrating and functioning effectively.
Another significant hurdle that clinicians encounter when treating solid tumors is their heterogeneous composition of various cancer cell types. Some of these cells exhibit antigens recognizable by CAR-T cells, while others do not, complicating the design of CAR-T therapies that can target all tumor cells without harming healthy cells. Solid tumors also produce the protein Plasmin, which further impairs the immune system’s ability to break down FASL and eliminate cancer cells.
Researchers from the University of California, Davis investigated whether shielding FASL from plasmin could preserve its cancer-killing capabilities and enhance the efficacy of CAR-T therapy. They found that the human FASL protein contains a unique amino acid compared to other primates, making it more susceptible to degradation by plasmin. Their observations suggested that when FASL was cleaved, it lost its ability to kill tumor cells. However, after injecting an antibody that prevents plasmin from cleaving FASL, it remained intact and preserved its cancer-killing function.
Since directly studying cell behavior in the human body poses challenges, scientists culture tumor cells and cell lines in Petri dishes under controlled laboratory environments. To gain insights into plasmin’s role, the team examined ovarian cancer cell lines obtained from patients, discovering that CAR-T resistant cancer cells exhibited high plasmin activity.
They noted that combining ovarian cancer cells with elevated plasmin levels with normal cells displaying surface FASL diminished FASL levels in the normal cells. When they added FASL-protecting antibodies, CAR-T cells effectively eliminated not only the targeted cancer cells but also nearby cancer cells lacking the specific target antigen. These findings indicated that plasmin can cleave FASL in T cells and undermine CAR-T therapy, suggesting that safeguarding FASL may enhance CAR-T treatment’s effectiveness.
To assess whether tumor-generated plasmin can deactivate human FASL in more natural settings, researchers examined its function in live tumors within an active immune system. They implanted ovarian, mammary, and colorectal tumor cell lines from mice into genetically matched mice to elicit a natural immune response. When human FASL protein was directly injected into mouse tumors, the cancer cells remained intact. In contrast, injecting a drug that inhibits plasmin resulted in cancer cell death. Additionally, administering FASL-protecting antibodies also led to the elimination of cancer cells.
As a final experiment, the team aimed to determine whether activated T cells from the mice’s immune systems could penetrate the tumors and kill cancer cells. They implanted mice with both plasmin-positive and plasmin-negative tumors, treating both with drugs to enhance immune cell activity and boost FASL production.
They discovered that in tumors with low plasmin levels, mouse immune cells expressed high amounts of FASL on their surfaces, while in tumors with elevated plasmin levels, FASL was significantly reduced. Once again, injecting FASL-protected antibodies into these tumors increased FASL levels. The researchers concluded that plasmin can diminish the immune system’s ability to eliminate cancer cells by depleting FASL from immune cells.
In summary, the team found that tumors exploit plasmin to break down the protective protein FASL, evading immune system attacks. Based on their findings, they proposed that plasmin inhibitors or FASL-protected antibodies could augment the effectiveness of immunotherapy in treating cancer.
The narrative of Earth is one of transformation. Over 4.5 billion years, our planet has evolved from a scorching mass of molten rock and poisonous gases into a temperate and vibrant habitat teeming with diverse life forms. This evolution was punctuated by pauses, restarts, and cataclysmic events, as the intricate biogeochemical processes shaped the most extraordinary phases in Earth’s history.
Our understanding of this vast tale is largely thanks to rocks. They preserve the chronology of events that contributed to the surface’s stratification through various deposits. This intricate ordering is understood through hierarchies, and the scientific discipline dedicated to interpreting them is known as stratigraphy.
In Strata: A Story from Deep Time, journalist Laura Poppick delves into this nuanced science of rock interpretation, offering insights on how planets respond to and recover from periods of upheaval. “Through these layers, we glimpse ancient versions of our planet, gaining contextual awareness as we traverse through the present,” she observes.
Poppick highlights several transformative periods in Earth’s history, selecting four key episodes. The first examines the development of oxygen-rich atmospheres, tracking the evolution of photosynthesizing microorganisms and significant oxidative events that led to mass extinctions around 2.4 billion years ago.
The second segment discusses “Snowball Earth,” a period approximately 720 million years ago when many regions are believed to have frozen over. Following this, she explores the advent of mud and the subsequent rise of vegetation. Finally, the Mesozoic era, dominated by dinosaurs, records atmospheric carbon dioxide levels much higher than today’s due to volcanic activity, offering a framework to understand planetary responses to climate shifts.
“
Sedimentary rocks maintain a distinct layer system that clearly records the events that have shaped our planet’s surface. “
Throughout each episode, Poppick introduces geologists working to unravel the numerous unanswered questions regarding the timing and causes of these changes. She visits significant geological sites, from Newfoundland to the Australian Outback, where one can observe the strata that articulate these narratives.
The recurring theme emphasizes the importance of paying attention to rocks. To an untrained observer, they may appear ordinary; however, Poppick reminds us that “a trained eye discerns physical and chemical indicators—proxies—that reveal the characteristics of our planet during the formation of these rocks.” She underscores the value of geologists’ expertise.
This book is a remarkable attempt to make stratigraphy engaging. At times, it falters, and Poppick’s fragmented writing style led me to lose the thread of the narrative.
Her comparisons of geological transformations to human-centric changes sometimes felt uneasy. For instance, she likens the Mesozoic greenhouse climate to modern carbon emissions, though the historical era’s temperatures were so extreme that such analogies may be misleading, even at optimistic emission projections.
Another limitation lies in the currently incomplete nature of geoscience. Some of the pivotal questions raised by Poppick—including the true cause of Snowball Earth—remain unresolved or are subject to debate among different factions. By the end, I was left with a sense of uncertainty about what can be definitively stated. Yet, that unpredictability might be intrinsic to geology itself. “Nothing is immutable in stone as our understanding of geology continues to evolve, just like the rocks,” Poppick states.
Nevertheless, the book effectively captures the grandeur of the story embedded in rocks. It does so particularly well by showing how seemingly mundane observations about rocks can lead directly to profound insights into Earth’s history. Such revelations illuminate the stratigraphic process as Poppick examines overlooked outcrops, encouraging us to perceive the rocks in our surroundings with renewed appreciation.
“Hierarchies are, in many ways, love letters from a maturing Earth,” she argues. This book abundantly reveals the reasons to uncover the secrets they hold.
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Following the successful testing of techniques using solar group spacecraft, it may soon be possible to forecast significant solar storms capable of disrupting Earth’s electronics by more than half a day in advance.
The Sun periodically emits powerful plasma bursts known as coronal mass ejections (CMEs), which create strong magnetic fields that can harm electronics on our planet. While satellites and telescopes do monitor CME indicators, their predictions depend on the magnetic field within each CME, making it challenging to identify which emissions will be hazardous.
One of the most reliable instruments for assessing these magnetic fields is found in satellites positioned in gravity-stable orbits around the Earth, known as Lagrange Points. Though these satellites are positioned hundreds of thousands of kilometers away, they exist at only about 1% of the distance to the Sun, which contributes to their ability to provide warnings about the intensity of a CME within an hour of its impact.
Now, Emma Davis from Glaz and her colleagues at Austria’s Space Meteorological Office have discovered a method utilizing the European Space Agency’s solar orbiter to issue earlier alerts. “Solar Orbiters are primarily a scientific mission and not specifically designed for this purpose,” Davis explains. “This is an added benefit from unforeseen alignments during a CME event.”
On March 17th and 23rd of this year, two sets of CMEs were heading toward Earth while the solar orbiter was positioned between our planet and the Sun. Davis and her team leveraged the spacecraft’s magnetic field and solar wind speed measurements to model the internal magnetic architecture of each CME and anticipate the severity of the geomagnetic storms they would induce. Remarkably, the entire forecasting process required less than five minutes, allowing predictions 7 and 15 hours before the events reached Earth.
Davis noted that their predictions closely aligned with the actual geomagnetic strengths observed, which she found remarkable considering the dynamic changes the CME’s magnetic fields undergo as they approach Earth. “The fortunate aspect was that not many unexpected events occurred, and these CMEs behaved rather predictably,” she adds.
She cautions that upcoming storms may not follow the same predictable patterns and that determining the exact arrival time of these storms remains challenging, with uncertainties lasting several hours.
Nevertheless, she underscores the importance of real-time measurements once a CME departs from the Sun. Chris Scott from the University of Reading, UK, who was not part of this research, noted, “It provides an early indication of the potential configuration of the magnetic fields within each eruption.”
However, data from these two events alone are insufficient for fine-tuning predictive models, and further observations are essential before establishing reliable, specialized solar storm monitoring missions near the Sun, Scott concludes.
Astronomy’s Global Capital: Chile
Explore Chile’s astronomical wonders. Visit some of the world’s leading observatories and gaze upon a star-studded sky that boasts some of the clearest views on the planet.
In Mason Coyle’s exile, a human crew arrives on Mars
Shutterstock/Gorodenkoff
This month brings new releases from renowned authors like Cixin Liu, Stephen Baxter, and John Scalzi. I’m particularly interested in Ian McEwan’s journey into a submerged world of 2119 in Salt Crop. The tale chronicles the downfall of Mason Coil within a fledgling Martian colony, while also capturing my attention is the time-travel noir from the talented Nicholas Binge.
This month, I’m taking a classic route in the New Scientist Book Club with Ursula K. Le Guin’s 1974 masterpiece, The Dispossessed. Join us in reading and see how it stands against today’s best science fiction. But let’s not forget about September 2025…
Literary authors are turning to sci-fi—this isn’t unprecedented (who could forget the 2010s’ Solar?). In his latest, we’re taken back to 2014, reflecting on great poems never to be heard again. Fast-forward to 2119, as lowland Britain finds itself submerged. Scholar Tom Metcalfe delves into early 21st century archives, uncovering the myriad opportunities of the past. He discovers a clue that might lead to “the great lost poem”…
For fans of The Three-Body Problem, Cixin Liu presents a collection of short stories exploring first contact, artificial intelligence, and cosmic dread. With 32 stories included, expect explorations of devoured planets and interstellar crafts.
Three Body Problem adaptation in 2024
Ed Miller/Netflix
The hearth serves as the “celestial birthplace” of countless planets, where humanity has flourished for millennia. As an unknown foe covets the wealth of this realm, Commander Ula Breen strategizes to unite diverse forces and retaliate. Will she uncover humanity’s original purpose for coming here?
In a future where coastal cities are submerged and oceans teem with mutated fish, we follow Sailor Skipper, the youngest of three sisters who make a life by collecting and selling ocean plastic. When she receives a mysterious call for help from her oldest sister, Nora, who seeks a remedy for failing crops, she and another sister, Carmen, embark on a perilous journey across the sea. Kitasei, the author of Deep Sky and Stardust Grey, delivers an astonishing tale.
In a time-travel murder investigation, detective Julia Togrimsen (what a name!) returns from retirement to solve the case of a billionaire she once infiltrated. However, she discovers two bodies—both belonging to billionaire Bruno Donaldson. We loved Binge’s previous sci-fi thriller, Dissolution, and anticipate this next offering.
This marks Scalzi’s seventh installment in the Old Man’s War series. After a decade of peace in interstellar space, humanity faces the threat of war from the most advanced alien species yet. Caught in the tumult, bureaucrat Gretchen Trujillo receives a covert mission that could reshape the future for both humans and aliens.
I am captivated by the cover and premise of this new novel from the late author of William (which I enjoyed). Set in 2030, this tale reveals a human crew preparing the first Martian colony, only to discover a half-destroyed base. They must question three robots dispatched four years earlier, one of which is still missing…
In a desolate lab in the desert, Kinsey and her team unearth bizarre specimens in the sand. Breaking quarantine to bring one inside, they soon realize it seeks a new host.
This intriguing blend of horror, science fiction, and fantasy captures my attention. Set against a backdrop of ecological dread, Kinsey excavates two ancient bodies found in Somerset Fen, while also exploring “her own wildness,” alongside archaebotanist Nell.
The decommissioning of Palmer has played a significant role in contributing to sea level rise, particularly as certain regions of Antarctica face limited access, raising concerns among scientists regarding potential ice sheet collapses.
In a statement to NBC News, the National Science Foundation (NSF) announced plans to streamline resources by consolidating McMurdo, Amunsense Cott South Paul, and Palmer Station, with the goal of maintaining three research stations operating throughout the year in Antarctica.
A spokesperson for the U.S. Antarctic Program (USAP) mentioned that they aim to “maintain an active and influential presence in Antarctica while facilitating cutting-edge research in biology and glaciology.”
The NSF was the first to propose the termination of the lease this spring, following the Trump administration’s proposed budget cuts of 55%. Scientists expressed their disappointment that Congress initiated the process of abolishing the ship before finalizing its budget.
“Oceanologist Karos Moffat, an associate professor at the University of Delaware, discussed the budgets that have made advancements in both Senate and House appropriations committees.
The NSF is exploring alternative vessels to take on some of Palmer’s responsibilities and plans to return the vessel to its owner, Edison Chowest, a marine transport company based in Louisiana.
In 2024, the NSF finalized the charter of another Antarctic vessel, RV Laurence M. Gould, which has been upgraded to operate in sea ice, rather than utilizing icebreakers. This reduces the options available for enhancing research in polar oceanography and supporting Palmer Station, an annual base on the Antarctic Peninsula that previously depended on two ships.
The NSF mentioned on Friday that there are “alternatives” available to support and resupply Palmer Station, including commercial options.
Measuring 308 feet, the Palmer, named after a 19th-century seal captain, commenced its service in 1992, exploring various regions of Antarctica. The vessel accommodates approximately 22 crew members and can host around 45 scientists.
No other U.S. research vessels can fulfill all the missions that this polar icebreaker is designed for. The vessel is crucial for studying Antarctic ecology, the Southern Ocean carbon cycle, and monitoring the rate at which ice shelves recede and melt, ultimately influencing sea level rise.
Julia S. Werner of the University of Houston, second from the right, friend of Nathaniel B. Palmer.Courtesy Julia S. Werner
While satellites offer valuable data on the dynamics of ice sheet growth and reduction, the primary research on these changes relies on subsurface measurements.
Without such data, U.S. scientists will lack critical insights into the major ice sheets of the Southern Ocean, which are key to predicting future flooding risks in U.S. coastal cities. For instance, researchers highlight that other U.S. vessels are not suitable for safely accessing the notorious Swaitonga glacier, often referred to as the “end of the Apocalyptic Glacier.”
Researchers frequently describe the West Ku as a cork for a bottle that could rapidly drain the West Antarctic ice sheet, serving as a protective barrier against its collapse into the Amundsen Sea. This could result in a sea level rise exceeding 10 feet over a span of hundreds of thousands of years.
By the year 2100, the likelihood of such a collapse could elevate sea levels significantly beyond the 1-3 feet previously anticipated, as indicated in recent reports by the Intergovernmental Panel.
This disintegration could also alter ocean circulation patterns, affecting how quickly the ocean absorbs carbon, which remains an active area of research. Several studies suggest that current Earth temperatures may have surpassed the threshold for collapse, although further investigation is necessary.
Current shifts in mass and stability are influenced by factors occurring hundreds or thousands of feet beneath the water’s surface, necessitating optimal access through robotic instruments.
“To grasp the drastic changes occurring, it’s essential to be at the edge of the ice where it interacts with the ocean,” Werner explained. “And that’s precisely what this boat allows us to do.”
Scientists typically travel to Palmer every two years, using the data collected over the course of a month or more to advance their laboratory research.
The information gathered aboard the vessel is invaluable, enabling scientists to study ice comprehensively for over a decade, adding vital icebreakers to the U.S. science fleet and alleviating the longstanding backlog of researchers seeking fieldwork opportunities at Palmer.
Olson noted that the wreck lies in shallow waters approximately 20 feet deep. He observed that the bottom of the hull is mostly intact, while the ship’s sides are cut and flattened like fillets.
Tamara Thomsen, a maritime archaeologist at the State Historical Preservation Office of the Historical Society, dedicated several weeks to scrutinizing newspaper clippings, archival insurance records, and a database of port registrations, which is comparable to vehicle registrations.
Thomsen and her team also undertook diving missions to identify specific characteristics of the wreck.
Based on the ship’s exterior and its general wreckage location, the Historical Society confirmed that Olson had unearthed the long-lost remains of the Frank D. Barker.
“What’s fascinating about this wreck is that it’s all there,” Thomsen remarked. “It spreads across the bottom like a puzzle piece that you can visualize and reorganize.”
The 137-foot Frank D. Barker was constructed from wood in 1867 by veteran shipbuilder Simon G. Johnson in Clayton, New York. This canaler is specially designed for operation in the Great Lakes, as Thomsen explained. It was built to navigate the Welland Canal, which includes a series of locks that permit ships to bypass Niagara Falls, in addition to a combination of natural and modified waterways.
The Frank D. Barker primarily transported grain from the ports of Milwaukee and Chicago to Lake Ontario, and on westward voyages, it typically carried coal from Lake Erie’s ports to the Midwest, fueling factories and industries.
In 1887, the Frank D. Barker sailed from Manistee, Michigan, to Escanaba, Michigan, to load a cargo of iron ore. Unfortunately, the ship’s captain and crew strayed off course due to inclement weather and fog.
Ultimately, the vessel ran aground and was stranded by blown limestone on Spider Island. Multiple attempts to salvage the ship in October 1887 and again in August, September, and October of 1888 were unsuccessful.
“They finally concluded that they couldn’t retrieve it from where it was stuck and decided to abandon the ship,” Thomsen explained.
According to the Wisconsin Historical Society, the estimated loss of the ship was around $8,000 at the time, which translates to over $250,000 today.
Rediscovering the Frank D. Barker after 138 years is a momentous occasion for Door County, but it holds personal significance for Olson as well.
After informing the state’s historic preservation office about the findings, Olson chose to delve deeper into the exploration.
“When I think about my six-year-old son snorkeling on a shipwreck for the first time,” he shared.
Nearly two months following the devastating July 4 flood in Texas, which claimed over 130 lives, D-Texas Rep. Lloyd Doggett continues to seek clarity on fundamental issues related to the federal response.
What emergency personnel were deployed by the National Weather Service on the night of the flood? How effectively did the agency prepare for the storm? And how did vacancies in critical local National Weather Service positions, like warning adjustment meteorologists, impact the situation?
In four letters sent to the National Oceanic and Atmospheric Administration, along with a fifth from the Commerce Department, Rep. Doggett requested records that could shed light on the events of July 4th.
“I have yet to receive any written response,” Doggett expressed, accusing the agency of evasion.
This push for transparency highlights the lack of public accountability regarding that day’s events. Shortly after the flood, an internal meteorologist indicated that the National Weather Service provided a timely warning, citing the constraints of their forecasting technology during flash flooding.
However, it remains unclear how effectively the agency communicated with emergency managers and other ground stakeholders when risks became evident. A former NWS meteorologist commented on the difficulties faced when their forecasts are compromised by staff shortages or overwhelming workloads.
Lloyd Doggett at the U.S. Capitol in 2024. Tom Williams/CQ-Roll Call, Inc via Getty Images File
“If there’s nothing to conceal, and if Trump’s budget cuts haven’t impacted weather services, then they need to create logs,” Doggett remarked regarding the records he seeks. “Drawing public attention to this issue may be the only way to prompt a response from the administration.”
Neither NOAA nor the Commerce Department has responded to requests for comment.
Doggett wrote his initial letter to NOAA on May 20, prior to the flood, raising concerns about staffing levels in the Austin/San Antonio weather office. This office is responsible for forecasts and communications in areas that faced significant impacts from the July storm.
“The 22% vacancy rate in the local NWS jeopardizes the timeliness of forecasts and alerts that communities depend on,” Doggett stated, inquiring about how the agency would address staff shortages and fulfill their operational roles.
Following the flood disaster, Doggett subsequently contacted NOAA on July 8 with 15 more questions about their responses. He reported having a video conference with agency director Ken Graham on July 11.
In a letter sent after their July 11 meeting and a follow-up on July 24, Doggett requested call logs, chat logs, radar archives, and shift logs from the agency.
“He mentioned that providing these was straightforward,” Doggett noted, recalling Graham’s remarks during the Zoom call. “I’ve been following up since then, but there’s been no satisfactory explanation.”
The agency is permitted to respond at its discretion to queries from Congress members overseeing it. Interpretation of the Department of Justice Law. Nonetheless, agencies often voluntarily address congressional inquiries.
Doggett has persistently contacted NOAA via phone and text, and in a letter to Commerce Secretary Howard Luttonick on August 27, he accused the Secretary of suppressing responses that he believes NOAA was ready to provide.
“I recommend that responses to my inquiries be prepared, but these have been withheld by your office,” Doggett wrote. “There’s no documentation demonstrating NWS’s preparation, communication, or response—perhaps indicating that some aspects of this tragedy are being concealed.”
Doggett mentioned that four children from Austin lost their lives in the floods and has called for an investigation similar to those conducted by the National Transportation Safety Board after significant disasters.
“If 27 children perish in a plane crash, the NTSB conducts a thorough investigation of all involved parties at state, federal, and local levels,” Doggett remarked.
NBC News has submitted multiple Freedom of Information Act (FOIA) requests to NOAA seeking records from NWS. Some of these requests might yield records that address Doggett’s inquiries, but thus far, there has been no response.
According to the Commerce Department’s Public Records website, one of the requested chat logs and communications between forecasters is currently “assigned for processing.” The agency indicated that information regarding staff cuts and recruitment will be managed in batches alongside other similar requests related to the Texas flood.
“We aim to provide a provisional release by early September, with additional releases occurring periodically through the end of the year,” wrote Julia Swanson, FOIA Coordinator, in an August 18 status update. “To effectively allocate limited staff resources, all other FOIA requests are temporarily set aside to prioritize addressing flood-related inquiries in Texas.”
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